Publications
Selected publications
- Kalanchoe PPC1 Is Essential for Crassulacean Acid Metabolism and the Regulation of Core Circadian Clock and Guard Cell Signaling Genes([CC-BY]) (Journal article - 2020)
- Phosphorylation of Phosphoenolpyruvate Carboxylase Is Essential for Maximal and Sustained Dark CO2 Fixation and Core Circadian Clock Operation in the Obligate Crassulacean Acid Metabolism Species Kalanchoe fedtschenkoi (Journal article - 2017)
- C4 and crassulacean acid metabolism within a single leaf: deciphering key components behind a rare photosynthetic adaptation. (Journal article - 2020)
- Emerging model systems for functional genomics analysis of Crassulacean acid metabolism (Journal article - 2016)
- Transgenic perturbation of the decarboxylation phase of Crassulacean acid metabolism alters physiology and metabolism but has only a small effect on growth (Journal article - 2015)
- CAM guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate. (Journal article - 2020)
- Stomatal Responses to Light, CO<sub>2</sub>, and Mesophyll Tissue in <i>Vicia faba</i> and <i>Kalanchoe fedtschenkoi</i> (Journal article - 2021)
- A matter of time: regulatory events behind the synchronization of C-4 and crassulacean acid metabolism in Portulaca oleracea (Journal article - 2022)
- The Kalanchoe genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism (Journal article - 2017)
- A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world (Journal article - 2015)
2024
Regulation of Crassulacean Acid Metabolism at the protein level in the CAM plant Kalanchoë laxiflora
2023
The starch-deficient plastidic PHOSPHOGLUCOMUTASE mutant of the constitutive crassulacean acid metabolism (CAM) species Kalanchoe fedtschenkoi impacts diel regulation and timing of stomatal CO<sub>2</sub> responsiveness
Hurtado-Castano, N., Atkins, E., Barnes, J., Boxall, S. F., Dever, L. V., Knerova, J., . . . Borland, A. M. (2023). The starch-deficient plastidic PHOSPHOGLUCOMUTASE mutant of the constitutive crassulacean acid metabolism (CAM) species Kalanchoe fedtschenkoi impacts diel regulation and timing of stomatal CO<sub>2</sub> responsiveness. ANNALS OF BOTANY. doi:10.1093/aob/mcad017
The Calvin-Benson-Bassham cycle in C<sub>4</sub> and Crassulacean acid metabolism species.
Ludwig, M., Hartwell, J., Raines, C. A., & Simkin, A. J. (2023). The Calvin-Benson-Bassham cycle in C<sub>4</sub> and Crassulacean acid metabolism species.. Seminars in cell & developmental biology, S1084-9521(23)00151-9. doi:10.1016/j.semcdb.2023.07.013
Producing fast and active Rubisco in tobacco to enhance photosynthesis
Chen, T., Riaz, S., Davey, P., Zhao, Z., Sun, Y., Dykes, G., . . . Liu, L. (n.d.). Producing fast and active Rubisco in tobacco to enhance photosynthesis. The Plant Cell. doi:10.1093/plcell/koac348
2022
A matter of time: regulatory events behind the synchronization of C-4 and crassulacean acid metabolism in Portulaca oleracea
Ferrari, R. C., Kawabata, A. B., Ferreira, S. S., Hartwell, J., & Freschi, L. (2022). A matter of time: regulatory events behind the synchronization of C-4 and crassulacean acid metabolism in Portulaca oleracea. JOURNAL OF EXPERIMENTAL BOTANY, 73(14), 4867-4885. doi:10.1093/jxb/erac163
2021
Down-Regulation of Phosphoenolpyruvate Carboxylase Kinase in Grapevine Cell Cultures and Leaves Is Linked to Enhanced Resveratrol Biosynthesis
Hurtado-Gaitan, E., Selles-Marchart, S., Hartwell, J., Martinez-Esteso, M. J., & Bru-Martinez, R. (2021). Down-Regulation of Phosphoenolpyruvate Carboxylase Kinase in Grapevine Cell Cultures and Leaves Is Linked to Enhanced Resveratrol Biosynthesis. BIOMOLECULES, 11(11). doi:10.3390/biom11111641
Stomatal Responses to Light, CO<sub>2</sub>, and Mesophyll Tissue in <i>Vicia faba</i> and <i>Kalanchoe fedtschenkoi</i>
Santos, M. G., Davey, P. A., Hofmann, T. A., Borland, A., Hartwell, J., & Lawson, T. (2021). Stomatal Responses to Light, CO<sub>2</sub>, and Mesophyll Tissue in <i>Vicia faba</i> and <i>Kalanchoe fedtschenkoi</i>. FRONTIERS IN PLANT SCIENCE, 12. doi:10.3389/fpls.2021.740534
Phosphorolytic degradation of leaf starch via plastidic α-glucan phosphorylase leads to optimized plant growth and water use efficiency over the diel phases of Crassulacean acid metabolism
Ceusters, N., Ceusters, J., Hurtado-Castano, N., Dever, L. V., Boxall, S. F., Knerova, J., . . . Borland, A. M. (2021). Phosphorolytic degradation of leaf starch via plastidic α-glucan phosphorylase leads to optimized plant growth and water use efficiency over the diel phases of Crassulacean acid metabolism. JOURNAL OF EXPERIMENTAL BOTANY, 72(12), 4419-4434. doi:10.1093/jxb/erab132
2020
Developing Portulaca oleracea as a model system for functional genomics analysis of C4/CAM photosynthesis
Callegari Ferrari, R., Pires Bittencourt, P., Yumi Nagumo, P., Silva Oliveira, W., Aurineide Rodrigues, M., Hartwell, J., & Freschi, L. (2020). Developing Portulaca oleracea as a model system for functional genomics analysis of C4/CAM photosynthesis. Functional Plant Biology. doi:10.1071/fp20202
CAM guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate.
Lefoulon, C., Boxall, S. F., Hartwell, J., & Blatt, M. R. (2020). Crassulacean acid metabolism guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate. NEW PHYTOLOGIST, 227(6), 1847-1857. doi:10.1111/nph.16640
Exploring C<sub>4</sub>-CAM plasticity within the <i>Portulaca oleracea</i> complex
Ferrari, R. C., Cruz, B. C., Gastaldi, V. D., Storl, T., Ferrari, E. C., Boxall, S. F., . . . Freschi, L. (2020). Exploring C<sub>4</sub>-CAM plasticity within the <i>Portulaca oleracea</i> complex. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-71012-y
Kalanchoe PPC1 Is Essential for Crassulacean Acid Metabolism and the Regulation of Core Circadian Clock and Guard Cell Signaling Genes([CC-BY])
Boxall, S. F., Kadu, N., Dever, L. V., Knerova, J., Waller, J. L., Gould, P. J. D., & Hartwell, J. (2020). Kalanchoe PPC1 Is Essential for Crassulacean Acid Metabolism and the Regulation of Core Circadian Clock and Guard Cell Signaling Genes([CC-BY]). The Plant Cell, 32(4), 1136-1160. doi:10.1105/tpc.19.00481
C4 and crassulacean acid metabolism within a single leaf: deciphering key components behind a rare photosynthetic adaptation.
Ferrari, R. C., Bittencourt, P. P., Rodrigues, M. A., Moreno-Villena, J. J., Alves, F. R. R., Gastaldi, V. D., . . . Freschi, L. (2020). C4 and crassulacean acid metabolism within a single leaf: deciphering key components behind a rare photosynthetic adaptation.. The New Phytologist, 225(4), 1699-1714. doi:10.1111/nph.16265
2019
Silencing PHOSPHOENOLPYRUVATE CARBOXYLASE1 in the Obligate Crassulacean Acid Metabolism Species Kalanchoë laxiflora causes Reversion to C3-like Metabolism and Amplifies Rhythmicity in a Subset of Core Circadian Clock Genes
Boxall, S., Kadu, N., Dever, L., Kneřová, J., Waller, J., Gould, P., & Hartwell, J. (2019). Silencing<i>PHOSPHOENOLPYRUVATE CARBOXYLASE1</i>in the Obligate Crassulacean Acid Metabolism Species<i>Kalanchoë laxiflora</i>causes Reversion to C<sub>3</sub>-like Metabolism and Amplifies Rhythmicity in a Subset of Core Circadian Clock Genes. doi:10.1101/684050
2018
The Circadian Clock in<scp>CAM</scp>Plants
Hartwell, J. (n.d.). The Circadian Clock in<scp>CAM</scp>Plants. In Unknown Book (pp. 211-236). Wiley. doi:10.1002/9781119312994.apr0214
2017
The Kalanchoe genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism
Yang, X., Hu, R., Yin, H., Jenkins, J., Shu, S., Tang, H., . . . Tuskan, G. A. (2017). The Kalanchoe genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism. NATURE COMMUNICATIONS, 8. doi:10.1038/s41467-017-01491-7
Phosphorylation of Phosphoenolpyruvate Carboxylase Is Essential for Maximal and Sustained Dark CO2 Fixation and Core Circadian Clock Operation in the Obligate Crassulacean Acid Metabolism Species Kalanchoe fedtschenkoi
Boxall, S. F., Dever, L. V., Knerova, J., Gould, P. D., & Hartwell, J. (2017). Phosphorylation of Phosphoenolpyruvate Carboxylase Is Essential for Maximal and Sustained Dark CO2 Fixation and Core Circadian Clock Operation in the Obligate Crassulacean Acid Metabolism Species Kalanchoe fedtschenkoi. PLANT CELL, 29(10), 2519-2536. doi:10.1105/tpc.17.00301
2016
Emerging model systems for functional genomics analysis of Crassulacean acid metabolism
Hartwell, J., Dever, L. V., & Boxall, S. F. (2016). Emerging model systems for functional genomics analysis of Crassulacean acid metabolism. CURRENT OPINION IN PLANT BIOLOGY, 31, 100-108. doi:10.1016/j.pbi.2016.03.019
2015
Climate-resilient agroforestry: physiological responses to climate change and engineering of crassulacean acid metabolism (CAM) as a mitigation strategy
Borland, A. M., Wullschleger, S. D., Weston, D. J., Hartwell, J., Tuskan, G. A., Yang, X., & Cushman, J. C. (2015). Climate-resilient agroforestry: physiological responses to climate change and engineering of crassulacean acid metabolism (CAM) as a mitigation strategy. PLANT CELL AND ENVIRONMENT, 38(9), 1833-1849. doi:10.1111/pce.12479
A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world
Yang, X., Cushman, J. C., Borland, A. M., Edwards, E. J., Wullschleger, S. D., Tuskan, G. A., . . . Holtum, J. A. M. (2015). A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world. NEW PHYTOLOGIST, 207(3), 491-504. doi:10.1111/nph.13393
A comparison of high-throughput techniques for assaying circadian rhythms in plants
Tindall, A. J., Waller, J., Greenwood, M., Gould, P. D., Hartwell, J., & Hall, A. (2015). A comparison of high-throughput techniques for assaying circadian rhythms in plants. PLANT METHODS, 11. doi:10.1186/s13007-015-0071-9
Transgenic perturbation of the decarboxylation phase of Crassulacean acid metabolism alters physiology and metabolism but has only a small effect on growth
Dever, L., Boxall, S., Knerova, J., & Hartwell, J. (2015). Transgenic perturbation of the decarboxylation phase of Crassulacean acid metabolism alters physiology and metabolism but has only a small effect on growth. Plant Physiology, 167(1), 44-59. doi:10.1104/pp.114.251827
2014
Engineering crassulacean acid metabolism to improve water-use efficiency
Borland, A. M., Hartwell, J., Weston, D. J., Schlauch, K. A., Tschaplinski, T. J., Tuskan, G. A., . . . Cushman, J. C. (2014). Engineering crassulacean acid metabolism to improve water-use efficiency. TRENDS IN PLANT SCIENCE, 19(5), 327-338. doi:10.1016/j.tplants.2014.01.006
2013
Parallel Recruitment of Multiple Genes into C<sub>4</sub> Photosynthesis
Christin, P. -A., Boxall, S. F., Gregory, R., Edwards, E. J., Hartwell, J., & Osborne, C. P. (2013). Parallel Recruitment of Multiple Genes into C<sub>4</sub> Photosynthesis. GENOME BIOLOGY AND EVOLUTION, 5(11), 2174-2187. doi:10.1093/gbe/evt168
2012
Adaptive Evolution of C<sub>4</sub> Photosynthesis through Recurrent Lateral Gene Transfer
Christin, P. -A., Edwards, E. J., Besnard, G., Boxall, S. F., Gregory, R., Kellogg, E. A., . . . Osborne, C. P. (2012). Adaptive Evolution of C<sub>4</sub> Photosynthesis through Recurrent Lateral Gene Transfer. CURRENT BIOLOGY, 22(5), 445-449. doi:10.1016/j.cub.2012.01.054
2011
Proteomic and transcriptomic analysis reveals evidence for the basis of salt sensitivity in Thai jasmine rice (<i>Oryza sativa</i> L. cv. KDML 105)
Jankangram, W., Thammasirirak, S., Jones, M. G., Hartwell, J., & Theerakulpisut, P. (2011). Proteomic and transcriptomic analysis reveals evidence for the basis of salt sensitivity in Thai jasmine rice (<i>Oryza sativa</i> L. cv. KDML 105). AFRICAN JOURNAL OF BIOTECHNOLOGY, 10(72), 16157-16166. doi:10.5897/AJB11.1559
2010
The Origins of C<sub>4</sub> Grasslands: Integrating Evolutionary and Ecosystem Science
Edwards, E. J., Osborne, C. P., Stroemberg, C. A. E., Smith, S. A., Bond, W. J., Christin, P. -A., . . . Tipple, B. (2010). The Origins of C<sub>4</sub> Grasslands: Integrating Evolutionary and Ecosystem Science. SCIENCE, 328(5978), 587-591. doi:10.1126/science.1177216
Characterisation of the Circadian Clock in Barley and its Effect on Fitness and Yield
Cotter, S., Hall, A., Hartwell, J., & Salem, R. (2010). Characterisation of the Circadian Clock in Barley and its Effect on Fitness and Yield. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 46, S16. Retrieved from https://www.webofscience.com/
2009
Distinct patterns of control and expression amongst members of the PEP carboxylase kinase gene family in C<sub>4</sub> plants (vol 48, pg 43, 2006)
Shenton, M., Fontaine, V., Hartwell, J., Marsh, J. T., Jenkins, G. I., & Nimmo, H. G. (2009). Distinct patterns of control and expression amongst members of the PEP carboxylase kinase gene family in C<sub>4</sub> plants (vol 48, pg 43, 2006). PLANT JOURNAL, 59(1), 192. doi:10.1111/j.1365-313X.2009.03858.x
Exploiting the potential of plants with crassulacean acid metabolism for bioenergy production on marginal lands
Borland, A. M., Griffiths, H., Hartwell, J., & Smith, J. A. C. (2009). Exploiting the potential of plants with crassulacean acid metabolism for bioenergy production on marginal lands. JOURNAL OF EXPERIMENTAL BOTANY, 60(10), 2879-2896. doi:10.1093/jxb/erp118
Delayed fluorescence as a universal tool for the measurement of circadian rhythms in higher plants
Gould, P. D., Diaz, P., Hogben, C., Kusakina, J., Salem, R., Hartwell, J., & Hall, A. (2009). Delayed fluorescence as a universal tool for the measurement of circadian rhythms in higher plants. PLANT JOURNAL, 58(5), 893-901. doi:10.1111/j.1365-313X.2009.03819.x
Ecological implications of plants' ability to tell the time
Resco, V., Hartwell, J., & Hall, A. (2009). Ecological implications of plants' ability to tell the time. ECOLOGY LETTERS, 12(6), 583-592. doi:10.1111/j.1461-0248.2009.01295.x
2008
Investigating effects of temperature on the circadian clock in plants
Kusakina, J., Hartwell, J., & Hall, A. (2008). Investigating effects of temperature on the circadian clock in plants. In COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY Vol. 150 (pp. S154). doi:10.1016/j.cbpa.2008.04.397
Molecular dissection of the circadian clock output pathway that mediates the temporal coordination of Crassulacean acid metabolism
Meszter, R., Boxall, S., Jones, M., & Hartwell, J. (2008). Molecular dissection of the circadian clock output pathway that mediates the temporal coordination of Crassulacean acid metabolism. In COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY Vol. 150 (pp. S153). doi:10.1016/j.cbpa.2008.04.394
The critical role of the <i>Arabidopsis</i> circadian clock at high temperature
Costa, N., Hartwell, J., & Hall, A. (2008). The critical role of the <i>Arabidopsis</i> circadian clock at high temperature. Retrieved from https://www.webofscience.com/
2007
The circadian clock in CAM plants
Hartwell, J. (2005). The circadian clock in CAM plants. In ENDOGENOUS PLANT RHYTHMS (Vol. 21, pp. 211-236). Retrieved from https://www.webofscience.com/
2006
Distinct patterns of control and expression amongst members of the PEP carboxylase kinase gene family in C<sub>4</sub> plants
Shenton, M., Fontaine, V., Hartwell, J., Marsh, J. T., Jenkins, G. I., & Nimmo, H. G. (2006). Distinct patterns of control and expression amongst members of the PEP carboxylase kinase gene family in C<sub>4</sub> plants. PLANT JOURNAL, 48(1), 45-53. doi:10.1111/j.1365-313X.2006.02850.x
Circadian control of isoprene emissions from oil palm (<i>Elaeis guineensis</i>)
Wilkinson, M. J., Owen, S. M., Possell, M., Hartwell, J., Gould, P., Hall, A., . . . Hewitt, C. N. (2006). Circadian control of isoprene emissions from oil palm (<i>Elaeis guineensis</i>). PLANT JOURNAL, 47(6), 960-968. doi:10.1111/j.1365-313X.2006.02847.x
2005
The co-ordination of central plant metabolism by the circadian clock.
Hartwell, J. (2005). The co-ordination of central plant metabolism by the circadian clock.. Biochemical Society transactions, 33(Pt 5), 945-948. doi:10.1042/bst20050945
Conservation and divergence of circadian clock operation in a stress-inducible crassulacean acid metabolism species reveals clock compensation against stress
Boxall, S. F., Foster, J. M., Bohnert, H. J., Cushman, J. C., Nimmo, H. G., & Hartwell, J. (2005). Conservation and divergence of circadian clock operation in a stress-inducible crassulacean acid metabolism species reveals clock compensation against stress. PLANT PHYSIOLOGY, 137(3), 969-982. doi:10.1104/pp.104.054577
2003
Structure and expression of phospho<i>enol</i>pyruvate carboxylase kinase genes in solanaceae.: A novel gene exhibits alternative splicing
Marsh, J. T., Sullivan, S., Hartwell, J., & Nimmo, H. O. (2003). Structure and expression of phospho<i>enol</i>pyruvate carboxylase kinase genes in solanaceae.: A novel gene exhibits alternative splicing. PLANT PHYSIOLOGY, 133(4), 2021-2028. doi:10.1104/pp.103.030775
2002
Probing the circadian control of phosphoenolpyruvate carboxylase kinase expression in <i>Kalanchoe fedtschenkoi</i>
Hartwell, J., Nimmo, G. A., Wilkins, M. B., Jenkins, G. I., & Nimmo, H. G. (2002). Probing the circadian control of phosphoenolpyruvate carboxylase kinase expression in <i>Kalanchoe fedtschenkoi</i>. FUNCTIONAL PLANT BIOLOGY, 29(6), 663-668. doi:10.1071/PP01208
<i>Arabidopsis thaliana</i> contains two phosphoenolpyruvate carboxylase kinase genes with different expression patterns
Fontaine, V., Hartwell, J., Jenkins, G. I., & Nimmo, H. G. (2002). <i>Arabidopsis thaliana</i> contains two phosphoenolpyruvate carboxylase kinase genes with different expression patterns. PLANT CELL AND ENVIRONMENT, 25(1), 115-122. doi:10.1046/j.0016-8025.2001.00805.x
2001
PEP carboxylase kinase is a novel protein kinase controlled at the level of expression
Nimmo, H. G., Fontaine, V., Hartwell, J., Jenkins, G. I., Nimmo, G. A., & Wilkins, M. B. (2001). PEP carboxylase kinase is a novel protein kinase controlled at the level of expression. NEW PHYTOLOGIST, 151(1), 91-97. doi:10.1046/j.1469-8137.2001.00155.x
1999
Metabolite control overrides circadian regulation of phospho<i>enol</i>pyruvate carboxylase kinase and CO<sub>2</sub> fixation in Crassulacean acid metabolism
Borland, A. M., Hartwell, J., Jenkins, G. I., Wilkins, M. B., & Nimmo, H. G. (1999). Metabolite control overrides circadian regulation of phospho<i>enol</i>pyruvate carboxylase kinase and CO<sub>2</sub> fixation in Crassulacean acid metabolism. PLANT PHYSIOLOGY, 121(3), 889-896. doi:10.1104/pp.121.3.889
Phosphoenolpyruvate carboxylase kinase is a novel protein kinase regulated at the level of expression
Hartwell, J., Gill, A., Nimmo, G. A., Wilkins, M. B., Jenkins, G. I., & Nimmo, H. G. (1999). Phosphoenolpyruvate carboxylase kinase is a novel protein kinase regulated at the level of expression. The Plant Journal, 20(3), 333-342. doi:10.1046/j.1365-313x.1999.00609.x
Phosphoenolpyruvate carboxylase kinase is a novel protein kinase regulated at the level of expression
Hartwell, J., Gill, A., Nimmo, G. A., Wilkins, M. B., Jenkins, G. L., & Nimmo, H. G. (1999). Phosphoenolpyruvate carboxylase kinase is a novel protein kinase regulated at the level of expression. PLANT JOURNAL, 20(3), 333-342. doi:10.1046/j.1365-313X.1999.t01-1-00609.x
The light induction of maize phosphoenolpyruvate carboxylase kinase translatable mRNA requires transcription but not translation
Hartwell, J., Jenkins, G. I., Wilkins, M. B., & Nimmo, H. G. (1999). The light induction of maize phosphoenolpyruvate carboxylase kinase translatable mRNA requires transcription but not translation. PLANT CELL AND ENVIRONMENT, 22(7), 883-889. doi:10.1046/j.1365-3040.1999.00455.x
1996
Higher plant phosphoenolpyruvate carboxylase kinase is regulated at the level of translatable mRNA in response to light or a circadian rhythm
Hartwell, J., Smith, L. H., Wilkins, M. B., Jenkins, G. I., & Nimmo, H. G. (1996). Higher plant phosphoenolpyruvate carboxylase kinase is regulated at the level of translatable mRNA in response to light or a circadian rhythm. PLANT JOURNAL, 10(6), 1071-1078. doi:10.1046/j.1365-313X.1996.10061071.x
Recycling of carbon in the oxidative pentose phosphate pathway in non-photosynthetic plastids
Hartwell, J., Bowsher, C. G., & Emes, M. J. (1996). Recycling of carbon in the oxidative pentose phosphate pathway in non-photosynthetic plastids. PLANTA, 200(1), 107-112. Retrieved from https://www.webofscience.com/
1995
Molecular phylogenetics of Lilianae
Chase, M. W., Duvall, M. R., Hills, H. G., Conran, J. G., Cox, A. V., Eguiarte, L. E., . . . Hoot, S. (1995). Molecular phylogenetics of Lilianae. In P. J. Rudall, P. J. Cribb, D. F. Cutler, & C. J. Humphries (Eds.), Monocotyledons: systematics and evolution (pp. 109-137). London, UK: Royal Botanics Gardens, Kew.
Undated
Functional genomics of Crassulacean acid metabolism in the monocot biomass feedstock crop Agave sisalana
Bupphada, P. (n.d.). Functional genomics of Crassulacean acid metabolism in the monocot biomass feedstock crop Agave sisalana. (PhD Thesis, University of Liverpool).