Publications
Selected publications
- T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study (Journal article - 2022)
- In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A) (Conference Paper - 2018)
- Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life (Journal article - 2014)
- Circulating Histone Levels Correlate with the Severity of COVID-19 and the Extent of Coagulation Activation and Inflammation (Conference Paper - 2020)
- Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells (Journal article - 2019)
- Circulating histones play a central role in COVID-19-associated coagulopathy and mortality (Journal article - 2021)
2022
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway (vol 7, pg 1161, 2022)
Willett, B. J., Grove, J., MacLean, O. A., Wilkie, C., De Lorenzo, G., Furnon, W., . . . Thomson, E. C. (2022). SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway (vol 7, pg 1161, 2022). NATURE MICROBIOLOGY, 7(10), 1709. doi:10.1038/s41564-022-01241-6
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Willett, B. J., Grove, J., MacLean, O. A., Wilkie, C., De Lorenzo, G., Furnon, W., . . . Thomson, E. C. (2022). SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. NATURE MICROBIOLOGY, 7(8), 1161-+. doi:10.1038/s41564-022-01143-7
T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study
Angyal, A., Longet, S., Moore, S. C., Payne, R. P., Harding, A., Tipton, T., . . . de, S. T. I. (2022). T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study. LANCET MICROBE, 3(1), E21-E31. doi:10.1016/S2666-5247(21)00275-5
2021
Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine
Payne, R. P., Longet, S., Austin, J. A., Skelly, D. T., Dejnirattisai, W., Adele, S., . . . Dunachie, S. (2021). Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine. CELL, 184(23), 5699-+. doi:10.1016/j.cell.2021.10.011
Circulating histones play a central role in COVID-19-associated coagulopathy and mortality
Shaw, R. J., Abrams, S. T., Austin, J., Taylor, J. M., Lane, S., Dutt, T., . . . Toh, C. -H. (2021). Circulating histones play a central role in COVID-19-associated coagulopathy and mortality. HAEMATOLOGICA, 106(9), 2493-2498. doi:10.3324/haematol.2021.278492
2020
Circulating Histone Levels Correlate with the Severity of COVID-19 and the Extent of Coagulation Activation and Inflammation
Shaw, R. J., Austin, J., Taylor, J., Dutt, T., Wang, G., Abrams, S. T., & Toh, C. H. (2020). Circulating Histone Levels Correlate with the Severity of COVID-19 and the Extent of Coagulation Activation and Inflammation. In BLOOD Vol. 136. doi:10.1182/blood-2020-142344
The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development
Cheng, Z., Abrams, S. T., Austin, J., Toh, J., Wang, S. S., Wang, Z., . . . Wang, G. (2020). The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development. MEDIATORS OF INFLAMMATION, 2020. doi:10.1155/2020/7418342
2019
Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells
Austin, J. A., Jenkins, R. E., Austin, G. M., Glenn, M. A., Dunn, K., Scott, L., . . . Clark, R. E. (2019). Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells. BIOCHEMICAL JOURNAL, 476, 2255-2269. doi:10.1042/BCJ20190121
CIP2A alters energy metabolism in CML cells, thus contributing to TKI resistance
Austin, J. A., Austin, G., Glenn, M., Dunn, K., Scott, L., Lucas, C., & Clark, R. (2019). CIP2A alters energy metabolism in CML cells, thus contributing to TKI resistance. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 185 (pp. 54). Retrieved from https://www.webofscience.com/
CIP2A regulates PP2A by altering the profile of PP2A B subunits
Austin, J., Austin, G., Holcroft, A., Scott, L., Clark, R., & Lucas, C. (2019). CIP2A regulates PP2A by altering the profile of PP2A B subunits. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 185 (pp. 10-11). Retrieved from https://www.webofscience.com/
2018
In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A)
Austin, J. A., Lucas, C. M., Jenkins, R. E., Dunn, K., Scott, L. J., Glenn, M. A., . . . Clark, R. E. (2018). In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A). In BRITISH JOURNAL OF HAEMATOLOGY Vol. 181 (pp. 52-53). Retrieved from https://www.webofscience.com/
2016
Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography
Miller, R. L., Guimond, S. E., Shivkumar, M., Blocksidge, J., Austin, J. A., Leary, J. A., & Turnbull, J. E. (2016). Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography. Analytical Chemistry, 88(23), 11542-11550. doi:10.1021/acs.analchem.6b02801
THE ADVERSE EFFECTS OF CANCEROUS INHIBITOR OF PROTEIN PHOSPHATASE 2A, ARE LINKED WITH REDUCTION OF FUNCTIONAL B56GAMMA, A REGULATORY SUBUNIT OF PROTEIN PHOSPHATASE 2A, IN CHRONIC MYELOID LEUKAEMIA
Austin, J. A., Lucas, C. M., Scott, L., Holcroft, A., Wang, L., & Clark, R. E. (2016). THE ADVERSE EFFECTS OF CANCEROUS INHIBITOR OF PROTEIN PHOSPHATASE 2A, ARE LINKED WITH REDUCTION OF FUNCTIONAL B56GAMMA, A REGULATORY SUBUNIT OF PROTEIN PHOSPHATASE 2A, IN CHRONIC MYELOID LEUKAEMIA. In HAEMATOLOGICA Vol. 101 (pp. 182). Retrieved from https://www.webofscience.com/
2014
Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life
Austin, J. A., Wright, G. S. A., Watanabe, S., Grossmann, J. G., Antonyuk, S. V., Yamanaka, K., & Hasnain. (2014). Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life. Proceedings of the National Academy of Sciences of the United States of America, 111(11), 4309-4314. doi:10.1073/pnas.1317317111
Undated
Sustained T Cell Immunity, Protection and Boosting Using Extended Dosing Intervals of BNT162b2 mRNA Vaccine
Payne, R. P., Longet, S., Austin, J. A., Skelly, D., Dejnirattisai, W., Adele, S., . . . Consortium, T. P. I. T. C. H. (n.d.). Sustained T Cell Immunity, Protection and Boosting Using Extended Dosing Intervals of BNT162b2 mRNA Vaccine.