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Publications

Selected publications

  1. T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study (Journal article - 2022)
  2. In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A) (Conference Paper - 2018)
  3. Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life (Journal article - 2014)
  4. Circulating Histone Levels Correlate with the Severity of COVID-19 and the Extent of Coagulation Activation and Inflammation (Conference Paper - 2020)
  5. Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells (Journal article - 2019)
  6. Circulating histones play a central role in COVID-19-associated coagulopathy and mortality (Journal article - 2021)
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2022

T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study

Angyal, A., Longet, S., Moore, S. C., Payne, R. P., Harding, A., Tipton, T., . . . de, S. T. I. (2022). T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study. LANCET MICROBE, 3(1), E21-E31. doi:10.1016/S2666-5247(21)00275-5

DOI
10.1016/S2666-5247(21)00275-5
Journal article

2021

2020

Circulating Histone Levels Correlate with the Severity of COVID-19 and the Extent of Coagulation Activation and Inflammation

Shaw, R. J., Austin, J., Taylor, J., Dutt, T., Wang, G., Abrams, S. T., & Toh, C. H. (2020). Circulating Histone Levels Correlate with the Severity of COVID-19 and the Extent of Coagulation Activation and Inflammation. In BLOOD Vol. 136. doi:10.1182/blood-2020-142344

DOI
10.1182/blood-2020-142344
Conference Paper

The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development

Cheng, Z., Abrams, S. T., Austin, J., Toh, J., Wang, S. S., Wang, Z., . . . Wang, G. (2020). The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development. MEDIATORS OF INFLAMMATION, 2020. doi:10.1155/2020/7418342

DOI
10.1155/2020/7418342
Journal article

2019

Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells

Austin, J. A., Jenkins, R. E., Austin, G. M., Glenn, M. A., Dunn, K., Scott, L., . . . Clark, R. E. (2019). Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells. BIOCHEMICAL JOURNAL, 476, 2255-2269. doi:10.1042/BCJ20190121

DOI
10.1042/BCJ20190121
Journal article

CIP2A alters energy metabolism in CML cells, thus contributing to TKI resistance

Austin, J. A., Austin, G., Glenn, M., Dunn, K., Scott, L., Lucas, C., & Clark, R. (2019). CIP2A alters energy metabolism in CML cells, thus contributing to TKI resistance. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 185 (pp. 54). Retrieved from https://www.webofscience.com/

Conference Paper

CIP2A regulates PP2A by altering the profile of PP2A B subunits

Austin, J., Austin, G., Holcroft, A., Scott, L., Clark, R., & Lucas, C. (2019). CIP2A regulates PP2A by altering the profile of PP2A B subunits. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 185 (pp. 10-11). Retrieved from https://www.webofscience.com/

Conference Paper

2018

In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A)

Austin, J. A., Lucas, C. M., Jenkins, R. E., Dunn, K., Scott, L. J., Glenn, M. A., . . . Clark, R. E. (2018). In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A). In BRITISH JOURNAL OF HAEMATOLOGY Vol. 181 (pp. 52-53). Retrieved from https://www.webofscience.com/

Conference Paper

2016

Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography

Miller, R. L., Guimond, S. E., Shivkumar, M., Blocksidge, J., Austin, J. A., Leary, J. A., & Turnbull, J. E. (2016). Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography. Analytical Chemistry, 88(23), 11542-11550. doi:10.1021/acs.analchem.6b02801

DOI
10.1021/acs.analchem.6b02801
Journal article

THE ADVERSE EFFECTS OF CANCEROUS INHIBITOR OF PROTEIN PHOSPHATASE 2A, ARE LINKED WITH REDUCTION OF FUNCTIONAL B56GAMMA, A REGULATORY SUBUNIT OF PROTEIN PHOSPHATASE 2A, IN CHRONIC MYELOID LEUKAEMIA

Austin, J. A., Lucas, C. M., Scott, L., Holcroft, A., Wang, L., & Clark, R. E. (2016). THE ADVERSE EFFECTS OF CANCEROUS INHIBITOR OF PROTEIN PHOSPHATASE 2A, ARE LINKED WITH REDUCTION OF FUNCTIONAL B56GAMMA, A REGULATORY SUBUNIT OF PROTEIN PHOSPHATASE 2A, IN CHRONIC MYELOID LEUKAEMIA. In HAEMATOLOGICA Vol. 101 (pp. 182). Retrieved from https://www.webofscience.com/

Conference Paper

2014

Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life

Austin, J. A., Wright, G. S. A., Watanabe, S., Grossmann, J. G., Antonyuk, S. V., Yamanaka, K., & Hasnain. (2014). Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life. Proceedings of the National Academy of Sciences of the United States of America, 111(11), 4309-4314. doi:10.1073/pnas.1317317111

DOI
10.1073/pnas.1317317111
Journal article

Undated

Sustained T Cell Immunity, Protection and Boosting Using Extended Dosing Intervals of BNT162b2 mRNA Vaccine

Payne, R. P., Longet, S., Austin, J. A., Skelly, D., Dejnirattisai, W., Adele, S., . . . Consortium, T. P. I. T. C. H. (n.d.). Sustained T Cell Immunity, Protection and Boosting Using Extended Dosing Intervals of BNT162b2 mRNA Vaccine.

Journal article