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Ian O'Neil

Dr Ian O'Neil
BSc ARCS PhD DIC

Contact

Ion@liverpool.ac.uk

+44 (0)151 794 1134

Publications

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2018

2017

2016

Tripodal Tris-N-oxides: Synthesis and Hydrogen Bonding Capabilities

Nixon, G., Billington, H., Kalindjian, S., Steiner, A., & O'Neil, I. (2016). Tripodal Tris-N-oxides: Synthesis and Hydrogen Bonding Capabilities. Synlett, 27(01), 141-145. doi:10.1055/s-0035-1560533

DOI
10.1055/s-0035-1560533
Journal article

2014

The synthesis and structure of chiral enamine N-oxides

O'Neil, I. A., McConville, M., Zhou, K., Brooke, C., Robertson, C. M., & Berry, N. G. (2014). The synthesis and structure of chiral enamine N-oxides. Chemical Communications, 50(55), 7336-7339. doi:10.1039/c3cc47928e

DOI
10.1039/c3cc47928e
Journal article

Selective trioxolane based bifunctional molecular linkers for covalent heme surface functionalisation

McConville, M., Bradley, D. F., Zhou, K., Schiffrin, D., & O'Neil, I. A. (2014). Selective trioxolane based bifunctional molecular linkers for covalent heme surface functionalisation. Chemical Communications, 50(2), 186-188. doi:10.1039/C3CC46041J

DOI
10.1039/C3CC46041J
Journal article

2012

2009

The synthesis of functionalised peptides using α-lithio quinuclidine N-oxide (Li-QNO)

O’Neil, I. A., & Bhamra, I. (2009). The synthesis of functionalised peptides using α-lithio quinuclidine N-oxide (Li-QNO). Tetrahedron Letters, 50(26), 3635-3638. doi:10.1016/j.tetlet.2009.03.105

DOI
10.1016/j.tetlet.2009.03.105
Journal article

2008

Directed lithiation on the quinuclidine ring system: the synthesis of 2,3-difunctionalised quinuclidines

O’Neil, I. A., Hitchin, J., Bhamra, I., Chorlton, A. P., & Tapolczay, D. J. (2008). Directed lithiation on the quinuclidine ring system: the synthesis of 2,3-difunctionalised quinuclidines. Tetrahedron Letters, 49(52), 7416-7418. doi:10.1016/j.tetlet.2008.10.064

DOI
10.1016/j.tetlet.2008.10.064
Journal article

A Concise Synthesis of Highly Functionalised 4-Thiosugar Derivatives

O'Neil, I. A., Southern, J. M., & Kearns, P. (2008). A Concise Synthesis of Highly Functionalised 4-Thiosugar Derivatives. Synlett, 2158-2160.

Journal article

2007

Lithiated Quinuclidine N-Oxide

O'Neil, I. (2007). Lithiated Quinuclidine N-Oxide.

Patent

The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy

Ellis, G. L., O'Neil, I. A., Ramos, V. E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy. TETRAHEDRON LETTERS, 48(10), 1687-1690. doi:10.1016/j.tetlet.2007.01.046

DOI
10.1016/j.tetlet.2007.01.046
Journal article

The synthesis of functionalised chiral bicyclic lactam and lactone N-oxides using a tandem Cope elimination/reverse Cope elimination protocol

Ellis, G. L., O'Neil, I. A., Ramos, V. E., Cleator, E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The synthesis of functionalised chiral bicyclic lactam and lactone N-oxides using a tandem Cope elimination/reverse Cope elimination protocol. TETRAHEDRON LETTERS, 48(10), 1683-1686. doi:10.1016/j.tetlet.2007.01.045

DOI
10.1016/j.tetlet.2007.01.045
Journal article

The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy

Ellis, G. L., O’Neil, I. A., Ramos, V. E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The diastereoselective synthesis of functionalised spirocyclic lactams and lactones using a Cope elimination/intramolecular nitrone cycloaddition strategy. Tetrahedron Letters, 48(10), 1687-1690. doi:10.1016/j.tetlet.2007.01.046

DOI
10.1016/j.tetlet.2007.01.046
Journal article

Syntheses of 2′-C-amidoalkyl and 2′-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA

Brennan, L., Cosstick, R., O'Neil, I. A., & Van Aerschot, A. (2007). Syntheses of 2′-C-amidoalkyl and 2′-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA. Tetrahedron, 63(3), 577-585. doi:10.1016/j.tet.2006.11.024

DOI
10.1016/j.tet.2006.11.024
Journal article

Synthesis of 2'-C-amidoalkyl and 2'-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA

Brennan, L., Cosstick, R., O'Neil, I. A., & Van Aerschot, A. (2007). Synthesis of 2'-C-amidoalkyl and 2'-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA. Tetrahedron, 63, 577-585.

Journal article

Synthesis of Highly Functionalised Morpholine Amine N-Oxides from Ephedrine and Pseudoephedrine Utilising the Reverse-Cope Elimination

O'Neil, I. A., & Henry, N. (2007). Synthesis of Highly Functionalised Morpholine Amine N-Oxides from Ephedrine and Pseudoephedrine Utilising the Reverse-Cope Elimination. Tetrahedron Letters, 48, 1691-1694.

Journal article

The Synthesis of Functionalised Chiral Bicyclic Lactam and Lactone N-Oxides using a Tandem Cope Elimination/Reverse-Cope Elimination Protocol

O'Neil, I., Ellis, G. L., Ramos, V. E., Kalindjian, S. B., Chorlton, A. P., & Tapolczay, D. J. (2007). The Synthesis of Functionalised Chiral Bicyclic Lactam and Lactone N-Oxides using a Tandem Cope Elimination/Reverse-Cope Elimination Protocol. Tetrahedron Letters, 48, 1683-1686.

Journal article

2006

Alpha-lithio quinuclidine N-oxide (Li-QNO): a new base for synthetic chemistry.

O'Neil, I. A., Bhamra, I., & Gibbons, P. D. (2006). Alpha-lithio quinuclidine N-oxide (Li-QNO): a new base for synthetic chemistry.. Chemical communications (Cambridge, England), (43), 4545-4547. doi:10.1039/b610533e

DOI
10.1039/b610533e
Journal article

Alpha-Lithio-Quinuclidine-N-Oxide (Li-QNO): A New Base for Synthetic Chemistry

O'Neil, I. A., Bhamra, I., & Gibbons, P. D. (2006). Alpha-Lithio-Quinuclidine-N-Oxide (Li-QNO): A New Base for Synthetic Chemistry. J. Chem. Soc., Chem. Commun, 4545-4547.

Journal article

2004

The diastereoselective synthesis of functionalised isoxazolidines using a Cope elimination/intramolecular nitrone cycloaddition strategy

O'Neil, I. A., Ramos, V. E., Ellis, G. L., Cleator, E., Chorlton, A. P., Tapolczay, D. J., & Kalindjian, S. B. (2004). The diastereoselective synthesis of functionalised isoxazolidines using a Cope elimination/intramolecular nitrone cycloaddition strategy. Tetrahedron Letters, 45(18), 3659-3661. doi:10.1016/j.tetlet.2004.03.041

DOI
10.1016/j.tetlet.2004.03.041
Journal article

The synthesis of chiral functionalised morpholine N-oxides using a tandem Cope elimination/reverse-Cope elimination protocol

O'Neil, I. A., Cleator, E., Elena Ramos, V., Chorlton, A. P., & Tapolczay, D. J. (2004). The synthesis of chiral functionalised morpholine N-oxides using a tandem Cope elimination/reverse-Cope elimination protocol. Tetrahedron Letters, 45(18), 3655-3658. doi:10.1016/j.tetlet.2004.03.040

DOI
10.1016/j.tetlet.2004.03.040
Journal article

Synthesis and transcription studies on 5'-triphosphates derived from 2'-C-branched-uridines: 2'-homouridine-5'-triphosphate is a substrate for T7 RNA polymerase.

Pavey, J. B. J., Lawrence, A. J., O'Neil, I. A., Vortler, S., & Cosstick, R. (2004). Synthesis and transcription studies on 5'-triphosphates derived from 2'-C-branched-uridines: 2'-homouridine-5'-triphosphate is a substrate for T7 RNA polymerase.. Organic & biomolecular chemistry, 2(6), 869-875. doi:10.1039/b314348a

DOI
10.1039/b314348a
Journal article

Synthesis of phosphorothioamidites derived from 3'-thio-3'-deoxythymidine and 3'-thio-2',3'-dideoxycytidine and the automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage.

Sabbagh, G., Fettes, K. J., Gosain, R., O'Neil, I. A., & Cosstick, R. (2004). Synthesis of phosphorothioamidites derived from 3'-thio-3'-deoxythymidine and 3'-thio-2',3'-dideoxycytidine and the automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage.. Nucleic acids research, 32(2), 495-501. doi:10.1093/nar/gkh189

DOI
10.1093/nar/gkh189
Journal article

Organometallics Zn, Cd, Hg, Cu, Ag, Au

O'Neil, I. A. (Ed.) (2004). Organometallics Zn, Cd, Hg, Cu, Ag, Au (Vol. 3). Stuttgart: Thieme.

Book

Preparation and reactions of Iminophosphoranes and their Synthetic Applications in the Aza-Wittig Reaction

O'Neil, I. A., & Southern, J. M. (2004). Preparation and reactions of Iminophosphoranes and their Synthetic Applications in the Aza-Wittig Reaction. In P. J. Murphy (Ed.), Organophosphorus Reagents (pp. 151-168). Oxford: Oxford University Press.

Chapter

2003

Isoquine and related amodiaquine analogues: A new generation of improved 4-aminoquinoline antimalarials

O'Neill, P. M., Mukhtar, A., Stocks, P. A., Randle, L. E., Hindley, S., Ward, S. A., . . . Park, B. K. (2003). Isoquine and related amodiaquine analogues: A new generation of improved 4-aminoquinoline antimalarials. JOURNAL OF MEDICINAL CHEMISTRY, 46(23), 4933-4945. doi:10.1021/jm030796n

DOI
10.1021/jm030796n
Journal article

Kinetics of electron transfer at Pt nanostructured film electrodes

Horswell, S. L., O'Neil, I. A., & Schiffrin, D. J. (2003). Kinetics of electron transfer at Pt nanostructured film electrodes. JOURNAL OF PHYSICAL CHEMISTRY B, 107(20), 4844-4854. doi:10.1021/jp0340257

DOI
10.1021/jp0340257
Journal article

Studies on 2'-alpha-C-carboxyalkyl nucleosides and their application to a stereocontrolled nucleobase exchange process.

Fehring, V., Knights, S., Chan, M. -Y., O'Neil, I. A., & Cosstick, R. (2003). Studies on 2'-alpha-C-carboxyalkyl nucleosides and their application to a stereocontrolled nucleobase exchange process.. Organic & biomolecular chemistry, 1(1), 123-128. doi:10.1039/b208786n

DOI
10.1039/b208786n
Journal article

2002

Probing the effect of a 3'-S-phosphorothiolate link on the conformation of a DNA:RNA hybrid; implications for antisense drug design.

Beevers, A. P. G., Fettes, K. J., O'Neil, I. A., Roberts, S. M., Arnold, J. R. P., Cosstick, R., & Fisher, J. (2002). Probing the effect of a 3'-S-phosphorothiolate link on the conformation of a DNA:RNA hybrid; implications for antisense drug design.. Chemical communications (Cambridge, England), (14), 1458-1459. doi:10.1039/b203582k

DOI
10.1039/b203582k
Journal article

2001

A convenient synthesis of secondary hydroxylamines

O'Neil, I. A., Cleator, E., & Tapolczay, D. J. (2001). A convenient synthesis of secondary hydroxylamines. Tetrahedron Letters, 42(46), 8247-8249. doi:10.1016/s0040-4039(01)01745-2

DOI
10.1016/s0040-4039(01)01745-2
Journal article

The stereospecific addition of hydroxylamines to α,β-unsaturated sulfones, nitriles and nitro compounds

O'Neil, I. A., Cleator, E., Southern, J. M., Bickley, J. F., & Tapolczay, D. J. (2001). The stereospecific addition of hydroxylamines to α,β-unsaturated sulfones, nitriles and nitro compounds. Tetrahedron Letters, 42(46), 8251-8254. doi:10.1016/s0040-4039(01)01746-4

DOI
10.1016/s0040-4039(01)01746-4
Journal article

The synthesis of β-N-tosylamino hydroxylamines via the ring opening of N-tosylaziridines and their use in reverse Cope cyclisations

O'Neil, I. A., Woolley, J. C., Southern, J. M., & Hobbs, H. (2001). The synthesis of β-N-tosylamino hydroxylamines via the ring opening of N-tosylaziridines and their use in reverse Cope cyclisations. Tetrahedron Letters, 42(46), 8243-8245. doi:10.1016/s0040-4039(01)01744-0

DOI
10.1016/s0040-4039(01)01744-0
Journal article

Novel macrocycles derived from nucleosides.

Calcerrada-Muñoz, N., O'Neil, I., & Cosstick, R. (2001). Novel macrocycles derived from nucleosides.. Nucleosides, nucleotides & nucleic acids, 20(4-7), 1347-1350. doi:10.1081/ncn-100002552

DOI
10.1081/ncn-100002552
Journal article

Potential modulated infrared reflectance spectroscopy of Pt-diisocyanide nanostructured electrodes

Horswell, S. L., O'Neil, I. A., & Schiffrin, D. J. (2001). Potential modulated infrared reflectance spectroscopy of Pt-diisocyanide nanostructured electrodes. JOURNAL OF PHYSICAL CHEMISTRY B, 105(5), 941-947. doi:10.1021/jp002661o

DOI
10.1021/jp002661o
Journal article

Solid-Phase Synthesis of Oligodeoxynucleotides Containing

Fettes, K. J., Roberts, S. M., O'Neil, I. A., & Cosstick, R. (2001). Solid-Phase Synthesis of Oligodeoxynucleotides Containing. Nucleosides and Nucleotides, 20, 1351-1354.

Journal article

Solid-phase synthesis of oligodeoxynucleotides containing 3'-S-phosphorothiolate linkages

Fettes, K., Roberts, S. M., O'Neil, I. A., & Cosstick, R. (2001). Solid-phase synthesis of oligodeoxynucleotides containing 3'-S-phosphorothiolate linkages. Nucleosides and Nucleotides, 20, 1351-1354.

Journal article

2000

A novel stereo-controlled nucleobase exchange process for the synthesis of 2′-C-branched nucleosides

Fehring, V., Chan, M. Y., O’Neil, I. A., & Cosstick, R. (2000). A novel stereo-controlled nucleobase exchange process for the synthesis of 2′-C-branched nucleosides. Journal of the Chemical Society, Perkin Transactions 1, (19), 3185-3187. doi:10.1039/b007099h

DOI
10.1039/b007099h
Journal article

The Synthesis and Functionalisation of Quinuclidine Enamine N-Oxide

O'Neil, I. A., Lai, J. Y. Q., & Wynn, D. (2000). The Synthesis and Functionalisation of Quinuclidine Enamine N-Oxide. Tetrahedron Letters, 41, 271-274.

Journal article

The Synthesis of Chiral Functionalised Piperidines Using a Reverse-Cope Cyclisation: The Effect of Solvent on Diastereoselectivity

O'Neil, I. A., Cleator, E., Southern, J. M., Hone, N., & Tapolczay, D. J. (2000). The Synthesis of Chiral Functionalised Piperidines Using a Reverse-Cope Cyclisation: The Effect of Solvent on Diastereoselectivity. Synlett, 695-697.

Journal article

The Synthesis of Chiral Polyhydroxylated Pyrrolidines Using a Reverse-Cope Cyclisation

The Synthesis of Chiral Polyhydroxylated Pyrrolidines Using a Reverse-Cope Cyclisation (2000). Synlett, 2000(10), 1408-1410. doi:10.1055/s-2000-7638

DOI
10.1055/s-2000-7638
Journal article

1999

Alkyl isocyanide-derivatized platinum nanoparticles

Horswell, S. L., Kiely, C. J., O'Neil, I. A., & Schiffrin, D. J. (1999). Alkyl isocyanide-derivatized platinum nanoparticles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 121(23), 5573-5574. doi:10.1021/ja984284n

DOI
10.1021/ja984284n
Journal article

Isolation and Chromatographic Purification of Reaction Products from alpha-Amino Acids,

O'Neil, I. A. (1999). Isolation and Chromatographic Purification of Reaction Products from alpha-Amino Acids,. In G. C. Barrett (Ed.), Amino Acid Derivatives (pp. 253-259). Oxford: Oxford University Press.

Chapter

Quinuclidine N-oxide: a potential replacement for HMPA

O’Neil, I. A., Wynn, D., & Lai, J. Y. Q. (1999). Quinuclidine N-oxide: a potential replacement for HMPA. Chemical Communications, (1), 59-60. doi:10.1039/a808779b

DOI
10.1039/a808779b
Journal article

Synthesis and duplex stability of oligodeoxyribonucleotides containing a 2′→5′-amide linkage

Chan, M. -Y., Fairhurst, R. A., Collingwood, S. P., Fisher, J., Arnold, J. R. P., Cosstick, R., & O’Neil, I. A. (1999). Synthesis and duplex stability of oligodeoxyribonucleotides containing a 2′→5′-amide linkage. Journal of the Chemical Society, Perkin Transactions 1, (3), 315-320. doi:10.1039/a808505f

DOI
10.1039/a808505f
Journal article

1998

The synthesis of functionalised β-hydroxyhydroxylamines via the ring opening of epoxides and their use in reverse Cope cyclisations

O'Neil, I. A., & Southern, J. M. (1998). The synthesis of functionalised β-hydroxyhydroxylamines via the ring opening of epoxides and their use in reverse Cope cyclisations. Tetrahedron Letters, 39(49), 9089-9092. doi:10.1016/s0040-4039(98)02001-2

DOI
10.1016/s0040-4039(98)02001-2
Journal article

Conformationally defined piperazine bis(<i>N-</i>oxides) bearing amino acid derived side chains

O'Neil, I. A., Potter, A. J., Southern, J. M., Steiner, A., & Barkley, J. V. (1998). Conformationally defined piperazine bis(<i>N-</i>oxides) bearing amino acid derived side chains. CHEMICAL COMMUNICATIONS, (22), 2511-2512. doi:10.1039/a806901h

DOI
10.1039/a806901h
Journal article

The synthesis of a novel 2′,3′-cyclic phosphate derived from 2′-homouridine

Pavey, J. B. J., Cosstick, R., & O'Neil, I. A. (1998). The synthesis of a novel 2′,3′-cyclic phosphate derived from 2′-homouridine. Tetrahedron Letters, 39(48), 8923-8924. doi:10.1016/s0040-4039(98)01952-2

DOI
10.1016/s0040-4039(98)01952-2
Journal article

DPPE: A convenient replacement for triphynylphosphine in the staudinger and Mitsunobu reactions

O'Neil, I. A., Thompson, S., Murray, C. L., & Kalindjian, S. B. (1998). DPPE: A convenient replacement for triphynylphosphine in the staudinger and Mitsunobu reactions. Tetrahedron Letters, 39(42), 7787-7790. doi:10.1016/s0040-4039(98)01702-x

DOI
10.1016/s0040-4039(98)01702-x
Journal article

The synthesis of 2′-homouridine, its incorporation into a dinucleoside monophosphate and hydrolytic behaviour of the dimer

Pavey, J. B. J., Lawrence, A. J., Potter, A. J., Cosstick, R., & O'Neil, I. A. (1998). The synthesis of 2′-homouridine, its incorporation into a dinucleoside monophosphate and hydrolytic behaviour of the dimer. Tetrahedron Letters, 39(38), 6967-6970. doi:10.1016/s0040-4039(98)01478-6

DOI
10.1016/s0040-4039(98)01478-6
Journal article

Simple Azetidine N-Oxides: Synthesis, Structure and Reactivity

O'Neil, I. A., & Potter, A. J. (1998). Simple Azetidine N-Oxides: Synthesis, Structure and Reactivity. J. Chem. Soc., Chem. Commun, 1487-1488.

Journal article

1997

A New Tin Mediated Pummerer Synthesis of Vinyl Stannanes

O'Neil, I., & Southern, J. (1997). A New Tin Mediated Pummerer Synthesis of Vinyl Stannanes. Synlett, 1997(10), 1165-1166. doi:10.1055/s-1997-987

DOI
10.1055/s-1997-987
Journal article

The highly stereoselective formation of pipecolic acid N-oxide and related derivatives

O'Neil, I. A., & Potter, A. J. (1997). The highly stereoselective formation of pipecolic acid N-oxide and related derivatives. Tetrahedron Letters, 38(32), 5731-5734. doi:10.1016/s0040-4039(97)01258-6

DOI
10.1016/s0040-4039(97)01258-6
Journal article

Homochiral Amine Oxides in the Enantioselective Reduction of Ketones

O'Neil, I., Turner, C., & Kalindjian, S. (1997). Homochiral Amine Oxides in the Enantioselective Reduction of Ketones. Synlett, 1997(7), 777-780. doi:10.1055/s-1997-5770

DOI
10.1055/s-1997-5770
Journal article

The synthesis of a novel benzodiazocine via an intramolecular Staudinger/aza-Wittig cyclization

O'Neil, I. A., Murray, C. L., Potter, A. J., & Kalindjian, S. B. (1997). The synthesis of a novel benzodiazocine via an intramolecular Staudinger/aza-Wittig cyclization. Tetrahedron Letters, 38(20), 3609-3610. doi:10.1016/s0040-4039(97)00680-1

DOI
10.1016/s0040-4039(97)00680-1
Journal article

"99Tcm-L,L-Ethylenedicysteine (EC) for ERPF: A Suitable Alternative

Noonan, E. C., Stringer, R., Maltby, P., Aldersey-Williams, B., O'Neil, I. A., & Turner, C. D. (1997). "99Tcm-L,L-Ethylenedicysteine (EC) for ERPF: A Suitable Alternative. Nuclear Medicine Communications, 18, 300-303.

Journal article

Synthesis, structure and reactions of uridine 2′-C,3′-O-γ-butyrolactone: versatile intermediate for the synthesis of 2′-C-branched nucleosides

Lawrence, A. J., Pavey, J. B. J., Chan, M. -Y., Fairhurst, R. A., Collingwood, S. P., Fisher, J., . . . O’Neil, I. A. (1997). Synthesis, structure and reactions of uridine 2′-C,3′-O-γ-butyrolactone: versatile intermediate for the synthesis of 2′-C-branched nucleosides. Journal of the Chemical Society, Perkin Transactions 1, (18), 2761-2768. doi:10.1039/a702088k

DOI
10.1039/a702088k
Journal article

The Synthesis of Functionalized Pyrrolo-[2,1-<i>c</i>][1,4]-Benzodiazepines

O'Neil, I., Murray, C., Hunter, R., Kalindjian, S., & Jenkins, T. (n.d.). The Synthesis of Functionalized Pyrrolo-[2,1-<i>c</i>][1,4]-Benzodiazepines. Synlett, 1(01), 75-78. doi:10.1055/s-1997-693

DOI
10.1055/s-1997-693
Journal article

The synthesis of 2'-C-functionalised nucleosides for incorporation into catalytic RNA

Lawrence, A. J., Pavey, J. B. J., ONeil, I. A., & Cosstick, R. (1997). The synthesis of 2'-C-functionalised nucleosides for incorporation into catalytic RNA. Nucleosides and Nucleotides, 16(7-9), 497-1501.

Journal article

1996

Synthesis and Properties of 2‘-Deoxy-2‘-α-<i>C</i>-branched Nucleosides and Nucleotides

Lawrence, A. J., Pavey, J. B. J., Cosstick, R., & O'Neil, I. A. (1996). Synthesis and Properties of 2‘-Deoxy-2‘-α-<i>C</i>-branched Nucleosides and Nucleotides. The Journal of Organic Chemistry, 61(26), 9213-9222. doi:10.1021/jo9614607

DOI
10.1021/jo9614607
Journal article

The total synthesis of (±)-trichoviridin

Baldwin, J. E., Adlington, R. M., O'Neil, I. A., Russell, A. T., & Smith, M. L. (n.d.). The total synthesis of (±)-trichoviridin. Chem. Commun., (1), 41-42. doi:10.1039/cc9960000041

DOI
10.1039/cc9960000041
Journal article

1995

A New Approach to the Synthesis of 4-Thio-1,2-Dideoxyribose

O’Neil, I. A., Hamilton, K. M., & Miller, J. A. (1995). A New Approach to the Synthesis of 4-Thio-1,2-Dideoxyribose. Synlett, 1995(10), 1053-1054. doi:10.1055/s-1995-5165

DOI
10.1055/s-1995-5165
Journal article

Homochiral Proline N-Oxides as Conformational Constraints in Peptide Like Molecules

O’Neil, I. A., Miller, N. D., Barkley, J. V., Low, C. M. R., & Kalindjian, S. B. (1995). Homochiral Proline N-Oxides as Conformational Constraints in Peptide Like Molecules. Synlett, 1995(06), 619-621. doi:10.1055/s-1995-5026

DOI
10.1055/s-1995-5026
Journal article

The Synthesis of Proline Derived Homochiral Amine Oxides

O’Neil, I. A., Miller, N. D., Barkley, J. V., Low, C. M. R., & Kalindjian, S. B. (1995). The Synthesis of Proline Derived Homochiral Amine Oxides. Synlett, 1995(06), 617-618. doi:10.1055/s-1995-5027

DOI
10.1055/s-1995-5027
Journal article

A Convenient Synthesis of 5-Substituted-2,3-Dihydrothiophenes

O’Neil, I. A., Hamilton, K. M., Miller, J. A., & Young, R. J. (1995). A Convenient Synthesis of 5-Substituted-2,3-Dihydrothiophenes. Synlett, 1995(02), 151-152. doi:10.1055/s-1995-4895

DOI
10.1055/s-1995-4895
Journal article

Synthesis of Functionalized 2'-C-Branched Nucleosides via their gamma-Butyrolactones

Lawrence, A. J., Pavey, J. B. J., O'Neil, I. A., & Cosstick, R. (1995). Synthesis of Functionalized 2'-C-Branched Nucleosides via their gamma-Butyrolactones. Tetrahedron Letters, 36(35), 6341-6343.

Journal article

The Synthesis of Isocyanides

O'Neil, I. A. (1995). The Synthesis of Isocyanides. In G. Pattenden, A. Katritzky, O. Meth Cohn, & C. W. Rees (Eds.), Comprehensive Functional Group Transformations (Vol. 3, pp. 693-726). Oxford: Pergamon Press.

Chapter

1993

The Novel Use of Proline Derived Amine Oxides in Controlling Amide Conformation

O'Neil, I. A., Miller, N. D., Peake, J., Barkley, J. V., Low, C. M. R., & Kalindjian, S. B. (1993). The Novel Use of Proline Derived Amine Oxides in Controlling Amide Conformation. Synlett, 1993(07), 515-518. doi:10.1055/s-1993-22513

DOI
10.1055/s-1993-22513
Journal article

1992

A Novel Method for the Coupling of Nucleoside Bases with Tetramethylene Sulphoxide

O'Neil, I., & Hamilton, K. (n.d.). A Novel Method for the Coupling of Nucleoside Bases with Tetramethylene Sulphoxide. Synlett, 1992(10), 791-792. doi:10.1055/s-1992-21491

DOI
10.1055/s-1992-21491
Journal article

1991

Isonitrin A: Revision of the Structure and Total Synthesis in Racemic Form

Baldwin, J. E., O'Neil, I. A., & Russell, A. T. (1991). Isonitrin A: Revision of the Structure and Total Synthesis in Racemic Form. Synlett, 1991(08), 551-552. doi:10.1055/s-1991-20792

DOI
10.1055/s-1991-20792
Journal article

Reverse Phase Flash Chromatography: A Convenient Method for the Large Scale Separation of Polar Compounds

O'Neil, I. A. (1991). Reverse Phase Flash Chromatography: A Convenient Method for the Large Scale Separation of Polar Compounds. Synlett, 1991(09), 661-662. doi:10.1055/s-1991-20833

DOI
10.1055/s-1991-20833
Journal article

1990

A new and mild procedure for the preparation of vinyl formamides from thiooximes

Baldwin, J. E., Aldous, D. J., & O'Neil, I. A. (1990). A new and mild procedure for the preparation of vinyl formamides from thiooximes. Tetrahedron Letters, 31(14), 2051-2054. doi:10.1016/s0040-4039(00)88913-3

DOI
10.1016/s0040-4039(00)88913-3
Journal article

The preparation of epoxy isonitriles (isocyanooxiranes)

Baldwin, J. E., & O'Neil, I. A. (1990). The preparation of epoxy isonitriles (isocyanooxiranes). Tetrahedron Letters, 31(14), 2047-2050. doi:10.1016/s0040-4039(00)88912-1

DOI
10.1016/s0040-4039(00)88912-1
Journal article

Trifluoromethanesulfonic Anhydride, a Superior Reagent for the Conversion of Formamides to Isonitriles

Baldwin, J. E., & O'Neil, I. A. (1990). Trifluoromethanesulfonic Anhydride, a Superior Reagent for the Conversion of Formamides to Isonitriles. Synlett, 1990(10), 603-604. doi:10.1055/s-1990-21181

DOI
10.1055/s-1990-21181
Journal article

1989

The Total Synthesis of (±)-lsonitrin B (Deoxytrichoviridin)

Baldwin, J., Aldous, D., Chan, C., Harwood, L., O'Neil, I., & Peach, J. (1989). The Total Synthesis of (±)-lsonitrin B (Deoxytrichoviridin). Synlett, 1989(1), 9-14. doi:10.1055/s-1989-34691

DOI
10.1055/s-1989-34691
Journal article

The ring opening of aziridine-2-carboxylate esters with organometallic reagents

Baldwin, J. E., Adlington, R. M., O'Neil, I. A., Schofield, C., Spivey, A. C., & Sweeney, J. B. (1989). The ring opening of aziridine-2-carboxylate esters with organometallic reagents. Journal of the Chemical Society, Chemical Communications, (23), 1852. doi:10.1039/c39890001852

DOI
10.1039/c39890001852
Journal article

1988

Tristrimethylsilylation of phenol and related reactions

Barrett, A. G. M., & O'Neil, I. A. (1988). Tristrimethylsilylation of phenol and related reactions. The Journal of Organic Chemistry, 53(8), 1815-1817. doi:10.1021/jo00243a044

DOI
10.1021/jo00243a044
Journal article

Reactions of a glycidyl radical equivalent with 2-functionalised allyl stannanes

Baldwin, J. E., Adlington, R. M., Lowe, C., O'Neil, I. A., Sanders, G. L., Schofield, C. J., & Sweeney, J. B. (1988). Reactions of a glycidyl radical equivalent with 2-functionalised allyl stannanes. Journal of the Chemical Society, Chemical Communications, (15), 1030. doi:10.1039/c39880001030

DOI
10.1039/c39880001030
Journal article

1986

Ultrasonic formation and reactions of sodium phenylselenide

Ley, S. V., O'Neil, L. A., & Low, C. M. R. (1986). Ultrasonic formation and reactions of sodium phenylselenide. Tetrahedron, 42(19), 5363-5368. doi:10.1016/s0040-4020(01)82086-x

DOI
10.1016/s0040-4020(01)82086-x
Journal article

1984

Preparation and reactions of 4-(trimethylsilyl)indole

Dauzonne, D., O'Neil, I. A., & Renaud, A. (1984). Preparation and reactions of 4-(trimethylsilyl)indole. The Journal of Organic Chemistry, 49(23), 4409-4415. doi:10.1021/jo00197a016

DOI
10.1021/jo00197a016
Journal article