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2024

2023

Monitoring Phenotype Heterogeneity at the Single-Cell Level within <i>Bacillus</i> Populations Producing Poly-3-hydroxybutyrate by Label-Free Super-resolution Infrared Imaging.

Lima, C., Muhamadali, H., & Goodacre, R. (2023). Monitoring Phenotype Heterogeneity at the Single-Cell Level within <i>Bacillus</i> Populations Producing Poly-3-hydroxybutyrate by Label-Free Super-resolution Infrared Imaging.. Analytical chemistry, 95(48), 17733-17740. doi:10.1021/acs.analchem.3c03595

DOI
10.1021/acs.analchem.3c03595
Journal article

Metabolomics of <i>Escherichia coli</i> for Disclosing Novel Metabolic Engineering Strategies for Enhancing Hydrogen and Ethanol Production

Valle, A., de la Calle, M. E., Muhamadali, H., Hollywood, K. A., Xu, Y., Lloyd, J. R., . . . Bolivar, J. (2023). Metabolomics of <i>Escherichia coli</i> for Disclosing Novel Metabolic Engineering Strategies for Enhancing Hydrogen and Ethanol Production. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(14). doi:10.3390/ijms241411619

DOI
10.3390/ijms241411619
Journal article

Unlocking the secrets of the microbiome: exploring the dynamic microbial interplay with humans through metabolomics and their manipulation for synthetic biology applications.

Muhamadali, H., Winder, C. L., Dunn, W. B., & Goodacre, R. (2023). Unlocking the secrets of the microbiome: exploring the dynamic microbial interplay with humans through metabolomics and their manipulation for synthetic biology applications.. The Biochemical journal, 480(12), 891-908. doi:10.1042/bcj20210534

DOI
10.1042/bcj20210534
Journal article

Optical photothermal infrared spectroscopy: A novel solution for rapid identification of antimicrobial resistance at the single-cell level <i>via</i> deuterium isotope labeling

Shams, S., Lima, C., Xu, Y., Ahmed, S., Goodacre, R., & Muhamadali, H. (2023). Optical photothermal infrared spectroscopy: A novel solution for rapid identification of antimicrobial resistance at the single-cell level <i>via</i> deuterium isotope labeling. FRONTIERS IN MICROBIOLOGY, 14. doi:10.3389/fmicb.2023.1077106

DOI
10.3389/fmicb.2023.1077106
Journal article

2022

2021

Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy

Kansiz, M., Spadea, A., Nallala, J., Lima, C., Muhamadali, H., Denbigh, J., . . . Klementieva, O. (2021). Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy. In G. J. Simpson, J. -X. Cheng, & W. Min (Eds.), Advanced Chemical Microscopy for Life Science and Translational Medicine 2021 (pp. 10). SPIE. doi:10.1117/12.2578662

DOI
10.1117/12.2578662
Conference Paper

2020

Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence

DOI
10.1101/2020.06.04.131862
Preprint

Surface Enhanced Raman Spectroscopy for Quantitative Analysis: Results of a Large-Scale European Multi-Instrument Interlaboratory Study

Fornasaro, S., Alsamad, F., Baia, M., Batista de Carvalho, L. A. E., Beleites, C., Byrne, H. J., . . . Bonifacio, A. (2020). Surface Enhanced Raman Spectroscopy for Quantitative Analysis: Results of a Large-Scale European Multi-Instrument Interlaboratory Study. ANALYTICAL CHEMISTRY, 92(5), 4053-4064. doi:10.1021/acs.analchem.9b05658

DOI
10.1021/acs.analchem.9b05658
Journal article

A microbiome and metabolomic signature of phases of cutaneous healing identified by profiling sequential acute wounds of human skin: An exploratory study

Ashrafi, M., Xu, Y., Muhamadali, H., White, I., Wilkinson, M., Hollywood, K., . . . Bayat, A. (2020). A microbiome and metabolomic signature of phases of cutaneous healing identified by profiling sequential acute wounds of human skin: An exploratory study. PLOS ONE, 15(2). doi:10.1371/journal.pone.0229545

DOI
10.1371/journal.pone.0229545
Journal article

2019

2018

Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins

Morra, R., Del Carratore, F., Muhamadali, H., Horga, L. G., Halliwell, S., Goodacre, R., . . . Dixon, N. (2018). Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins. MBIO, 9(1). doi:10.1128/mBio.02118-17

DOI
10.1128/mBio.02118-17
Journal article

Headspace volatile organic compounds from bacteria implicated in ventilator-associated pneumonia analysed by TD-GC/MS

Lawal, O., Muhamadali, H., Ahmed, W. M., White, I. R., Nijsen, T. M. E., Goodacre, R., & Fowler, S. J. (2018). Headspace volatile organic compounds from bacteria implicated in ventilator-associated pneumonia analysed by TD-GC/MS. JOURNAL OF BREATH RESEARCH, 12(2). doi:10.1088/1752-7163/aa8efc

DOI
10.1088/1752-7163/aa8efc
Journal article

Omics Methods For the Detection of Foodborne Pathogens

Ellis, D. I., Muhamadali, H., Chisanga, M., & Goodacre, R. (2019). Omics Methods For the Detection of Foodborne Pathogens. In Encyclopedia of Food Chemistry (pp. 364-370). Elsevier. doi:10.1016/b978-0-08-100596-5.21793-9

DOI
10.1016/b978-0-08-100596-5.21793-9
Chapter

2017

Towards improved quantitative analysis using surface-enhanced Raman scattering incorporating internal isotope labelling

Subaihi, A., Xu, Y., Muhamadali, H., Mutter, S. T., Blanch, E. W., Ellis, D. I., & Goodacre, R. (2017). Towards improved quantitative analysis using surface-enhanced Raman scattering incorporating internal isotope labelling. ANALYTICAL METHODS, 9(47), 6636-6644. doi:10.1039/c7ay02527k

DOI
10.1039/c7ay02527k
Journal article

SERS in biology/biomedical SERS: general discussion

Baumberg, J., Bell, S., Bonifacio, A., Chikkaraddy, R., Chisanga, M., Corsetti, S., . . . Wuytens, P. (2017). SERS in biology/biomedical SERS: general discussion. FARADAY DISCUSSIONS, 205, 429-456. doi:10.1039/c7fd90089a

DOI
10.1039/c7fd90089a
Journal article

Ultrasensitive and towards single molecule SERS: general discussion

Aizpurua, J., Arnolds, H., Baumberg, J., Bruzas, I., Chikkaraddy, R., Chisanga, M., . . . Willner, M. (2017). Ultrasensitive and towards single molecule SERS: general discussion. FARADAY DISCUSSIONS, 205, 291-330. doi:10.1039/C7FD90088K

DOI
10.1039/C7FD90088K
Journal article

Quantitative Online Liquid Chromatography Surface-Enhanced Raman Scattering (LC-SERS) of Methotrexate and its Major Metabolites

Subaihi, A., Trivedi, D. K., Hollywood, K. A., Bluett, J., Xu, Y., Muhamadali, H., . . . Goodacre, R. (2017). Quantitative Online Liquid Chromatography Surface-Enhanced Raman Scattering (LC-SERS) of Methotrexate and its Major Metabolites. ANALYTICAL CHEMISTRY, 89(12), 6702-6709. doi:10.1021/acs.analchem.7b00916

DOI
10.1021/acs.analchem.7b00916
Journal article

Quantitative detection of codeine in human plasma using surface-enhanced Raman scattering <i>via</i> adaptation of the isotopic labelling principle

Subaihi, A., Muhamadali, H., Mutter, S. T., Blanch, E., Ellis, D. I., & Goodacre, R. (2017). Quantitative detection of codeine in human plasma using surface-enhanced Raman scattering <i>via</i> adaptation of the isotopic labelling principle. ANALYST, 142(7), 1099-1105. doi:10.1039/c7an00193b

DOI
10.1039/c7an00193b
Journal article

2016

Rapid, Accurate, and Quantitative Detection of Propranolol in Multiple Human Biofluids via Surface-Enhanced Raman Scattering

Subaihi, A., Almanqur, L., Muhamadali, H., AlMasoud, N., Ellis, D. I., Trivedi, D. K., . . . Goodacre, R. (2016). Rapid, Accurate, and Quantitative Detection of Propranolol in Multiple Human Biofluids via Surface-Enhanced Raman Scattering. ANALYTICAL CHEMISTRY, 88(22), 10884-10892. doi:10.1021/acs.analchem.6b02041

DOI
10.1021/acs.analchem.6b02041
Journal article

Partial Least Squares with Structured Output for Modelling the Metabolomics Data Obtained from Complex Experimental Designs: A Study into the Y-Block Coding

Xu, Y., Muhamadali, H., Sayqal, A., Dixon, N., & Goodacre, R. (2016). Partial Least Squares with Structured Output for Modelling the Metabolomics Data Obtained from Complex Experimental Designs: A Study into the Y-Block Coding. METABOLITES, 6(4). doi:10.3390/metabo6040038

DOI
10.3390/metabo6040038
Journal article

Reverse and Multiple Stable Isotope Probing to Study Bacterial Metabolism and Interactions at the Single Cell Level

Wang, Y., Song, Y., Tao, Y., Muhamadali, H., Goodacre, R., Zhou, N. -Y., . . . Huang, W. E. (2016). Reverse and Multiple Stable Isotope Probing to Study Bacterial Metabolism and Interactions at the Single Cell Level. ANALYTICAL CHEMISTRY, 88(19), 9443-9450. doi:10.1021/acs.analchem.6b01602

DOI
10.1021/acs.analchem.6b01602
Journal article

Rapid, accurate, and comparative differentiation of clinically and industrially relevant microorganisms <i>via</i> multiple vibrational spectroscopic fingerprinting

Muhamadali, H., Subaihi, A., Mohammadtaheri, M., Xu, Y., Ellis, D. I., Ramanathan, R., . . . Goodacre, R. (2016). Rapid, accurate, and comparative differentiation of clinically and industrially relevant microorganisms <i>via</i> multiple vibrational spectroscopic fingerprinting. ANALYST, 141(17), 5127-5136. doi:10.1039/c6an00883f

DOI
10.1039/c6an00883f
Journal article

A flavour of omics approaches for the detection of food fraud

Ellis, D. I., Muhamadali, H., Allen, D. P., Elliott, C. T., & Goodacre, R. (2016). A flavour of omics approaches for the detection of food fraud. CURRENT OPINION IN FOOD SCIENCE, 10, 7-15. doi:10.1016/j.cofs.2016.07.002

DOI
10.1016/j.cofs.2016.07.002
Journal article

Rapid, high-throughput, and quantitative determination of orange juice adulteration by Fourier-transform infrared spectroscopy

Ellis, D. I., Ellis, J., Muhamadali, H., Xu, Y., Horn, A. B., & Goodacre, R. (2016). Rapid, high-throughput, and quantitative determination of orange juice adulteration by Fourier-transform infrared spectroscopy. ANALYTICAL METHODS, 8(28), 5581-5586. doi:10.1039/c6ay01480a

DOI
10.1039/c6ay01480a
Journal article

Metabolic analysis of the response of <i>Pseudomonas putida</i> DOT-T1E strains to toluene using Fourier transform infrared spectroscopy and gas chromatography mass spectrometry

Sayqal, A., Xu, Y., Trivedi, D. K., AlMasoud, N., Ellis, D. I., Muhamadali, H., . . . Goodacre, R. (2016). Metabolic analysis of the response of <i>Pseudomonas putida</i> DOT-T1E strains to toluene using Fourier transform infrared spectroscopy and gas chromatography mass spectrometry. METABOLOMICS, 12(7). doi:10.1007/s11306-016-1054-1

DOI
10.1007/s11306-016-1054-1
Journal article

Chicken, beams, and <i>Campylobacter</i>: rapid differentiation of foodborne bacteria via vibrational spectroscopy and MALDI-mass spectrometry

Muhamadali, H., Weaver, D., Subaihi, A., AlMasoud, N., Trivedi, D. K., Ellis, D. I., . . . Goodacre, R. (2016). Chicken, beams, and <i>Campylobacter</i>: rapid differentiation of foodborne bacteria via vibrational spectroscopy and MALDI-mass spectrometry. ANALYST, 141(1), 111-122. doi:10.1039/c5an01945a

DOI
10.1039/c5an01945a
Journal article

Metabolomic analysis of riboswitch containing <i>E-coli</i> recombinant expression system

Muhamadali, H., Xu, Y., Morra, R., Trivedi, D. K., Rattray, N. J. W., Dixon, N., & Goodacre, R. (2016). Metabolomic analysis of riboswitch containing <i>E-coli</i> recombinant expression system. MOLECULAR BIOSYSTEMS, 12(2), 350-361. doi:10.1039/c5mb00624d

DOI
10.1039/c5mb00624d
Journal article

2015

Point-and-shoot: rapid quantitative detection methods for on-site food fraud analysis - moving out of the laboratory and into the food supply chain

Ellis, D. I., Muhamadali, H., Haughey, S. A., Elliott, C. T., & Goodacre, R. (2015). Point-and-shoot: rapid quantitative detection methods for on-site food fraud analysis - moving out of the laboratory and into the food supply chain. ANALYTICAL METHODS, 7(22), 9401-9414. doi:10.1039/c5ay02048d

DOI
10.1039/c5ay02048d
Journal article

A systematic analysis of TCA <i>Escherichia coli</i> mutants reveals suitable genetic backgrounds for enhanced hydrogen and ethanol production using glycerol as main carbon source

Valle, A., Cabrera, G., Muhamadali, H., Trivedi, D. K., Ratray, N. J. W., Goodacre, R., . . . Bolivar, J. (2015). A systematic analysis of TCA <i>Escherichia coli</i> mutants reveals suitable genetic backgrounds for enhanced hydrogen and ethanol production using glycerol as main carbon source. BIOTECHNOLOGY JOURNAL, 10(11), 1750-1761. doi:10.1002/biot.201500005

DOI
10.1002/biot.201500005
Journal article

Metabolomics investigation of recombinant mTNFα production in <i>Streptomyces lividans</i>

Muhamadali, H., Xu, Y., Ellis, D. I., Trivedi, D. K., Rattray, N. J. W., Bernaerts, K., & Goodacre, R. (2015). Metabolomics investigation of recombinant mTNFα production in <i>Streptomyces lividans</i>. MICROBIAL CELL FACTORIES, 14. doi:10.1186/s12934-015-0350-1

DOI
10.1186/s12934-015-0350-1
Journal article

A tutorial review: Metabolomics and partial least squares-discriminant analysis - a marriage of convenience or a shotgun wedding

Gromski, P. S., Muhamadali, H., Ellis, D. I., Xu, Y., Correa, E., Turner, M. L., & Goodacre, R. (2015). A tutorial review: Metabolomics and partial least squares-discriminant analysis - a marriage of convenience or a shotgun wedding. ANALYTICA CHIMICA ACTA, 879, 10-23. doi:10.1016/j.aca.2015.02.012

DOI
10.1016/j.aca.2015.02.012
Journal article

Scale-up of the production of highly reactive biogenic magnetite nanoparticles using <i>Geobacter sulfurreducens</i>

Byrne, J. M., Muhamadali, H., Coker, V. S., Cooper, J., & Lloyd, J. R. (2015). Scale-up of the production of highly reactive biogenic magnetite nanoparticles using <i>Geobacter sulfurreducens</i>. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 12(107). doi:10.1098/rsif.2015.0240

DOI
10.1098/rsif.2015.0240
Journal article

Metabolic Profiling of <i>Geobacter sulfurreducens</i> during Industrial Bioprocess Scale-Up

Muhamadali, H., Xu, Y., Ellis, D. I., Allwood, J. W., Rattray, N. J. W., Correa, E., . . . Goodacre, R. (2015). Metabolic Profiling of <i>Geobacter sulfurreducens</i> during Industrial Bioprocess Scale-Up. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81(10), 3288-3298. doi:10.1128/AEM.00294-15

DOI
10.1128/AEM.00294-15
Journal article

Combining Raman and FT-IR Spectroscopy with Quantitative Isotopic Labeling for Differentiation of E. coli Cells at Community and Single Cell Levels

Muhamadali, H., Chisanga, M., Subaihi, A., & Goodacre, R. (2015). Combining Raman and FT-IR Spectroscopy with Quantitative Isotopic Labeling for Differentiation of E. coli Cells at Community and Single Cell Levels. Analytical Chemistry, 87(8), 4578-4586. doi:10.1021/acs.analchem.5b00892

DOI
10.1021/acs.analchem.5b00892
Journal article