Publications
2024
A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance
Maldonado, H., Dreger, M., Bedgood, L., Kyriakou, T., Wolanska, K., Rigby, M., . . . Morgan, M. (n.d.). A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance. Science Advances. Retrieved from https://doi.org/10.1126/sciadv.adk9944
Author Correction: Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function.
Maldonado, H., Savage, B. D., Barker, H. R., May, U., Vähätupa, M., Badiani, R. K., . . . Järvinen, T. A. H. (2024). Author Correction: Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function.. Nature communications, 15(1), 234. doi:10.1038/s41467-023-44574-4
2023
Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function
Maldonado, H., Savage, B. D., Barker, H. R., May, U., Vähätupa, M., Badiani, R. K., . . . Järvinen*, T. A. H. (2023). Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function. Nature Communications.
A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance
A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance
CSK-mediated signalling by integrins in cancer
Maldonado, H., & Leyton, L. (2023). CSK-mediated signalling by integrins in cancer. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 11. doi:10.3389/fcell.2023.1214787
2022
Exposure to the pro-inflammatory prostaglandin E2 disrupts E-cadherin/Caveolin1-mediated tumor suppression to favor Caveolin-1 enhanced migration, invasion and metastasis of melanoma cells
Lobos-Gonzalez, L., Orostica, L., Natalia, D., Rojas, V. M., Campos, A., Farfan, N., . . . Quest, A. F. (2022). Exposure to the pro-inflammatory prostaglandin E2 disrupts E-cadherin/Caveolin1-mediated tumor suppression to favor Caveolin-1 enhanced migration, invasion and metastasis of melanoma cells. In FEBS OPEN BIO Vol. 12 (pp. 95). Retrieved from https://www.webofscience.com/
2021
Soluble Thy-1 Reverses Established Lung Fibrosis in a Progressive Model
Hagood, J. S., Maldonado, H., Rivier, L., & Myers, G. (2021). Soluble Thy-1 Reverses Established Lung Fibrosis in a Progressive Model. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 203. Retrieved from https://www.webofscience.com/
Cooperative signaling between integrins and growth factor receptors in fibrosis
Maldonado, H., & Hagood, J. S. (2021). Cooperative signaling between integrins and growth factor receptors in fibrosis. JOURNAL OF MOLECULAR MEDICINE-JMM, 99(2), 213-224. doi:10.1007/s00109-020-02026-2
2020
Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells
Valdivia, A., Cardenas, A., Brenet, M., Maldonado, H., Kong, M., Diaz, J., . . . Leyton, L. (2020). Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells. CELL COMMUNICATION AND SIGNALING, 18(1). doi:10.1186/s12964-020-00629-3
2019
RAB8A and RAP1B cooperate to control integrin trafficking and function during angiogenic processes
Wolanska, K. I., Maldonado, H., George, A. V., Rusilowicz, E. V., Newman, D., Hammond, D., & Morgan, M. R. (2019). RAB8A and RAP1B cooperate to control integrin trafficking and function during angiogenic processes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A42). Retrieved from https://www.webofscience.com/
2018
Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk
Paul, N., Thomas, J., Maldonado, H., Wolanska, K., Koper, E., Humphries, J., . . . Morgan, M. (2018). Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk. doi:10.1101/405043
Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion
Thomas, J. R., Moore, K. M., Sproat, C., Mo, S., Wolanska, K. I., Maldonado, H., . . . Morgan, M. R. (2019). Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 100(4), A39. Retrieved from https://www.webofscience.com/
Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion
Thomas, J., Moore, K., Sproat, C., Maldonado-Lorca, H., Mo, S., Haider, S., . . . Morgan, M. (2018). Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion. doi:10.1101/407908
2017
Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells
Diaz-Valdivia, N. I., Calderon, C. C., Diaz, J. E., Lobos-Gonzalez, L., Sepulveda, H., Ortiz, R. J., . . . Quest, A. F. G. (2017). Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells. ONCOTARGET, 8(67), 111943-111965. doi:10.18632/oncotarget.22955
Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway
Maldonado, H., Calderon, C., Burgos-Bravo, F., Kobler, O., Zuschratter, W., Ramirez, O., . . . Leyton, L. (2017). Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1864(2), 243-254. doi:10.1016/j.bbamcr.2016.11.006
2014
Signaling Pathways Involved in Neuron-Astrocyte Adhesion and Migration
Cardenas, A., Kong, M., Alvarez, A., Maldonado, H., & Leyton, L. (2014). Signaling Pathways Involved in Neuron-Astrocyte Adhesion and Migration. CURRENT MOLECULAR MEDICINE, 14(2), 275-290. doi:10.2174/1566524014666140128113311
Anti-neoplastic drugs at sub lethal doses augment caveolin-1 expression and caveolin-1 dependent migration and invasion of cancer cells.
Diaz, N., Calderon, C., Diaz, J., Maldonado, H., Castillo, J., Ortiz, R., . . . Quest, A. (2014). Anti-neoplastic drugs at sub lethal doses augment caveolin-1 expression and caveolin-1 dependent migration and invasion of cancer cells.. In MOLECULAR BIOLOGY OF THE CELL Vol. 25. Retrieved from https://www.webofscience.com/
Csk-Binding-Protein mediates Thy-1 signaling and neurite retraction caused by astrocyte αvβ3 integrin in neuronal cultures.
Maldonado, H., Leyton, L., Quest, A., & Herrera-Molina, R. (2014). Csk-Binding-Protein mediates Thy-1 signaling and neurite retraction caused by astrocyte αvβ3 integrin in neuronal cultures.. In MOLECULAR BIOLOGY OF THE CELL Vol. 25. Retrieved from https://www.webofscience.com/
2012
Astrocytic α<sub>V</sub>β<sub>3</sub> Integrin Inhibits Neurite Outgrowth and Promotes Retraction of Neuronal Processes by Clustering Thy-1
Herrera-Molina, R., Frischknecht, R., Maldonado, H., Seidenbecher, C. I., Gundelfinger, E. D., Hetz, C., . . . Leyton, L. (2012). Astrocytic α<sub>V</sub>β<sub>3</sub> Integrin Inhibits Neurite Outgrowth and Promotes Retraction of Neuronal Processes by Clustering Thy-1. PLOS ONE, 7(3). doi:10.1371/journal.pone.0034295
2011
Inhibition of Cyclin-Dependent Kinase 5 but Not of Glycogen Synthase Kinase 3-β Prevents Neurite Retraction and Tau Hyperphosphorylation Caused by Secretable Products of Human T-Cell Leukemia Virus Type I-Infected Lymphocytes
Maldonado, H., Ramirez, E., Utreras, E., Pando, M. E., Kettlun, A. M., Chiong, M., . . . Valenzuela, M. A. (2011). Inhibition of Cyclin-Dependent Kinase 5 but Not of Glycogen Synthase Kinase 3-β Prevents Neurite Retraction and Tau Hyperphosphorylation Caused by Secretable Products of Human T-Cell Leukemia Virus Type I-Infected Lymphocytes. JOURNAL OF NEUROSCIENCE RESEARCH, 89(9), 1489-1498. doi:10.1002/jnr.22678
2009
Comparative Study of CSF Neurofilaments in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis and Other Neurological Disorders
Alberti, C., Gonzalez, J., Maldonado, H., Medina, F., Barriga, A., Garcia, L., . . . Valenzuela, M. (2009). Comparative Study of CSF Neurofilaments in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis and Other Neurological Disorders. AIDS RESEARCH AND HUMAN RETROVIRUSES, 25(8), 803-809. doi:10.1089/aid.2008.0262
2008
Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: An <i>in vitro</i> model of HTLV-I-induced disease
Maldonado, H., Ortiz-Riano, E., Krause, B., Barriga, A., Medina, F., Pando, M. E., . . . Antonieta Valenzuela, M. (2008). Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: An <i>in vitro</i> model of HTLV-I-induced disease. BIOLOGICAL RESEARCH, 41(3), 239-252. Retrieved from https://www.webofscience.com/