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Helen Clough

Dr Helen Clough
PhD. MSc.

Contact

H.E.Clough@liverpool.ac.uk

+44 (0)151 794 6170

Publications

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2024

2023

Comparison of statistical approaches to predicting norovirus laboratory reports before and during COVID-19: insights to inform public health surveillance.

Ondrikova, N., Clough, H., Douglas, A., Vivancos, R., Itturiza-Gomara, M., Cunliffe, N., & Harris, J. P. (2023). Comparison of statistical approaches to predicting norovirus laboratory reports before and during COVID-19: insights to inform public health surveillance.. Scientific reports, 13(1), 21457. doi:10.1038/s41598-023-48069-6

DOI
10.1038/s41598-023-48069-6
Journal article

Pint of Science festival - "What's in a number? Making sense of risk".

Clough, H. (2023, May 24). Pint of Science festival - "What's in a number? Making sense of risk". [Science public engagement festival - presentation]. Tempest on Tithebarn, Liverpool.

Performance

Understanding the impact of local funding cuts on environmental health and regulatory services and gastrointestinal infection outcomes: a longitudinal ecological study protocol

Murrell, L., Clough, H., Gibb, R., Zhang, X., Green, M., Chattaway, M., . . . Hungerford, D. (2023). Understanding the impact of local funding cuts on environmental health and regulatory services and gastrointestinal infection outcomes: a longitudinal ecological study protocol. doi:10.3310/nihropenres.13426.1

DOI
10.3310/nihropenres.13426.1
Journal article

2022

Predicting Norovirus in England Using Existing and Emerging Syndromic Data: Infodemiology Study (Preprint)

DOI
10.2196/preprints.37540
Preprint

2021

Differential impact of the COVID-19 pandemic on laboratory reporting of norovirus and <i>Campylobacter</i> in England: A modelling approach

Ondrikova, N., Clough, H. E., Douglas, A., Iturriza-Gomara, M., Larkin, L., Vivancos, R., . . . Cunliffe, N. A. (2021). Differential impact of the COVID-19 pandemic on laboratory reporting of norovirus and <i>Campylobacter</i> in England: A modelling approach. PLOS ONE, 16(8). doi:10.1371/journal.pone.0256638

DOI
10.1371/journal.pone.0256638
Journal article

2020

Coronavirus: patterns of illness and death mainly mirror what was already happening before the pandemic

McIntyre, K., Clough, H., Thaxton, G., Harris, J., & Rushton, J. (2020). Coronavirus: patterns of illness and death mainly mirror what was already happening before the pandemic. Retrieved from https://theconversation.com/

Internet publication

<i>Fasciola hepatica</i> in UK horses

Howell, A. K., Malalana, F., Beesley, N. J., Hodgkinson, J. E., Rhodes, H., Sekiya, M., . . . Williams, D. J. L. (2020). <i>Fasciola hepatica</i> in UK horses. EQUINE VETERINARY JOURNAL, 52(2), 194-199. doi:10.1111/evj.13149

DOI
10.1111/evj.13149
Journal article

2019

2018

Erratum for Graham-Brown et al., “Dairy Heifers Naturally Exposed to Fasciola hepatica Develop a Type 2 Immune Response and Concomitant Suppression of Leukocyte Proliferation”

Graham-Brown, J., Hartley, C., Clough, H., Kadioglu, A., Baylis, M., & Williams, D. J. L. (2018). Erratum for Graham-Brown et al., “Dairy Heifers Naturally Exposed to Fasciola hepatica Develop a Type 2 Immune Response and Concomitant Suppression of Leukocyte Proliferation”. Infection and Immunity, 86(6). doi:10.1128/IAI.00247-18

DOI
10.1128/IAI.00247-18
Journal article

Dairy heifers naturally exposed to Fasciola hepatica develop a type-2 immune response and concomitant suppression of leukocyte proliferation.

Graham-Brown, J., Hartley, C., Clough, H., Kadioglu, A., Baylis, M., & Williams, D. J. L. (2018). Dairy heifers naturally exposed to Fasciola hepatica develop a type-2 immune response and concomitant suppression of leukocyte proliferation.. Infection and Immunity, 86(1). doi:10.1128/iai.00607-17

DOI
10.1128/iai.00607-17
Journal article

2017

Study on the impact of liver fluke infection on the welfare of horses

Howell, A., Williams, D., Malalana, F., Archer, D., Hodgkinson, J., & Clough, H. (2017). Study on the impact of liver fluke infection on the welfare of horses. VETERINARY RECORD, 180(12). doi:10.1136/vr.j1405

DOI
10.1136/vr.j1405
Journal article

2015

2014

Effect of climate on performance parameters in outdoor pig herds in East Anglia

Bell, H., Clough, H. E., & Jones, P. H. (2014). Effect of climate on performance parameters in outdoor pig herds in East Anglia.

Journal article

2013

Semi-stochastic models for <i>Salmonella</i> infection within finishing pig units in the UK

Berriman, A. D. C., Clancy, D., Clough, H. E., & Christley, R. M. (2013). Semi-stochastic models for <i>Salmonella</i> infection within finishing pig units in the UK. MATHEMATICAL BIOSCIENCES, 245(2), 148-156. doi:10.1016/j.mbs.2013.06.004

DOI
10.1016/j.mbs.2013.06.004
Journal article

Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of <i>Salmonella</i> in UK Pig Herds

Berriman, A. D. C., Clancy, D., Clough, H. E., Armstrong, D., & Christley, R. M. (2013). Effectiveness of Simulated Interventions in Reducing the Estimated Prevalence of <i>Salmonella</i> in UK Pig Herds. PLOS ONE, 8(6). doi:10.1371/journal.pone.0066054

DOI
10.1371/journal.pone.0066054
Journal article

2012

Spatial and temporal patterns in antimicrobial resistance of Salmonella Typhimurium in cattle in England and Wales.

Cox, R., Su, T., Clough, H., Woodward, M. J., & Sherlock, C. (2012). Spatial and temporal patterns in antimicrobial resistance of Salmonella Typhimurium in cattle in England and Wales.. Epidemiology and infection, 140(11), 2062-2073. doi:10.1017/s0950268811002755

DOI
10.1017/s0950268811002755
Journal article

2011

The prevalence of antimicrobial-resistant <i>Escherichia coli</i> in sympatric wild rodents varies by season and host

Williams, N. J., Sherlock, C., Jones, T. R., Clough, H. E., Telfer, S. E., Begon, M., . . . Bennett, M. (2011). The prevalence of antimicrobial-resistant <i>Escherichia coli</i> in sympatric wild rodents varies by season and host. JOURNAL OF APPLIED MICROBIOLOGY, 110(4), 962-970. doi:10.1111/j.1365-2672.2011.04952.x

DOI
10.1111/j.1365-2672.2011.04952.x
Journal article

2010

Analysis of meat juice ELISA results and questionnaire data to investigate farm-level risk factors for Salmonella infection in UK pigs.

Smith, R. P., Clough, H. E., & Cook, A. J. C. (2010). Analysis of meat juice ELISA results and questionnaire data to investigate farm-level risk factors for Salmonella infection in UK pigs.. Zoonoses and public health, 57 Suppl 1, 39-48. doi:10.1111/j.1863-2378.2010.01362.x

DOI
10.1111/j.1863-2378.2010.01362.x
Journal article

2009

Case studies in Bayesian microbial risk assessments

Kennedy, M. C., Clough, H. E., & Turner, J. (2009). Case studies in Bayesian microbial risk assessments. ENVIRONMENTAL HEALTH, 8. doi:10.1186/1476-069X-8-S1-S19

DOI
10.1186/1476-069X-8-S1-S19
Journal article

Review of diffusion models for the social amplification of risk of food-borne zoonoses

Mehers, J. P., Clough, H. E., & Christley, R. M. (2009). Review of diffusion models for the social amplification of risk of food-borne zoonoses. In SAFETY, RELIABILITY AND RISK ANALYSIS: THEORY, METHODS AND APPLICATIONS, VOLS 1-4 (pp. 2317-2324). Retrieved from https://www.webofscience.com/

Conference Paper

Spatial and spatio-temporal analysis of Salmonella infection in dairy herds in England and Wales.

Fenton, S. E., Clough, H. E., Diggle, P. J., Evans, S. J., Davison, H. C., Vink, W. D., & French, N. P. (2009). Spatial and spatio-temporal analysis of Salmonella infection in dairy herds in England and Wales.. Epidemiology and infection, 137(6), 847-857. doi:10.1017/s0950268808001349

DOI
10.1017/s0950268808001349
Journal article

Quantifying exposure to Vero-cytotoxigenic <i>Escherichia coli</i> O157 in milk sold as pasteurized: A model-based approach

Clough, H. E., Clancy, D., & French, N. P. (2009). Quantifying exposure to Vero-cytotoxigenic <i>Escherichia coli</i> O157 in milk sold as pasteurized: A model-based approach. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 131(2-3), 95-105. doi:10.1016/j.ijfoodmicro.2008.12.036

DOI
10.1016/j.ijfoodmicro.2008.12.036
Journal article

Antimicrobial use in companion animal and equine practice

Hughes, L., Dawson, S., Clegg, P., Pinchbeck, G., Nuttall, T., Clough, H., & Williams, N. J. (2009). Antimicrobial use in companion animal and equine practice. VETERINARY RECORD, 164(19), 604. doi:10.1136/vr.164.19.604

DOI
10.1136/vr.164.19.604
Journal article

Evidence from the UK Zoonoses Action Plan in favour of localised anomalies of Salmonella infection on United Kingdom pig farms.

Clough, H. E., Fenton, S. E., French, N. P., Miller, A. J., & Cook, A. J. C. (2009). Evidence from the UK Zoonoses Action Plan in favour of localised anomalies of Salmonella infection on United Kingdom pig farms.. Preventive veterinary medicine, 89(1-2), 67-74. doi:10.1016/j.prevetmed.2009.01.008

DOI
10.1016/j.prevetmed.2009.01.008
Journal article

Bayesian Approaches in Microbial Risk Assessment

Oakley, J. E., & Clough, H. E. (2009). Bayesian Approaches in Microbial Risk Assessment. In A. O'Hagan, & M. West (Eds.), Handbook of Applied Bayesian Analysis (pp. 15). Oxford: Oxford University Press.

Chapter

Review of diffusion models for the social amplification of risk of food-borne zonooses

Mehers, J. P., Clough, H. E., & Christley, R. M. (2009). Review of diffusion models for the social amplification of risk of food-borne zonooses. Safety, reliability and risk analysis: theory, methods and applications, 1-4(2317-2).

Journal article

2007

Ecological differences and coexistence in a guild of microparasites: Bartonella in wild rodents

Telfer, S., Clough, H. E., Birtles, R. J., Bennett, M., Carslake, D., Helyar, S., & Begon, M. (2007). Ecological differences and coexistence in a guild of microparasites: Bartonella in wild rodents. Ecology, 88(7), 1841-1849.

Journal article

Ecological differences and coexistence in a guild of microparasites:: <i>Bartonella</i> in wild rodents

Telfer, S., Clough, H. E., Birtles, R. J., Bennett, M., Carslake, D., Helyar, S., & Begon, M. (2007). Ecological differences and coexistence in a guild of microparasites:: <i>Bartonella</i> in wild rodents. ECOLOGY, 88(7), 1841-1849. doi:10.1890/06-1004.1

DOI
10.1890/06-1004.1
Journal article

ZAP: The role of routine surveillance data in understanding the geography and timing of Salmonella on UK pig farms.

Clough, H., Sanderson, J., Brown, P., Miller, A., & Cook, A. J. C. (n.d.). ZAP: The role of routine surveillance data in understanding the geography and timing of Salmonella on UK pig farms.. In International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork (pp. 69-72). Iowa State University, Digital Press. doi:10.31274/safepork-180809-94

DOI
10.31274/safepork-180809-94
Conference Paper

2006

Vero-cytotoxigenic <i>Escherichia coli</i> O157 in pasteurized milk containers at the point of retail:: A qualitative approach to exposure assessment

Clough, H. E., Clancy, D., & French, N. P. (2006). Vero-cytotoxigenic <i>Escherichia coli</i> O157 in pasteurized milk containers at the point of retail:: A qualitative approach to exposure assessment. RISK ANALYSIS, 26(5), 1291-1309. doi:10.1111/j.1539-6924.2006.00825.x

DOI
10.1111/j.1539-6924.2006.00825.x
Journal article

Scientific Report on Animal health and welfare risks associated with the import of wild birds other than poultry into the European Union

Various. (2006). Scientific Report on Animal health and welfare risks associated with the import of wild birds other than poultry into the European Union. Parma: EFSA.

Report

Strain-typing Transmissible Spongiform Encephalopathies Using Replicated Spatial Data

Webster, S., Diggle, P. J., Clough, H. E., Green, R. B., & French, N. P. (n.d.). Strain-typing Transmissible Spongiform Encephalopathies Using Replicated Spatial Data. In Lecture Notes in Statistics (pp. 197-214). Springer-Verlag. doi:10.1007/0-387-31144-0_11

DOI
10.1007/0-387-31144-0_11
Chapter

Strain-typing Transmissible Spongiform Encephalopathies using replicated spatial data

Webster, S., Diggle, P. J., Clough, H. E., Green, R. B., & French, N. P. (2006). Strain-typing Transmissible Spongiform Encephalopathies using replicated spatial data. In A. J. Baddeley, P. Gregori, J. Mateu, R. Stoica, & D. Stoyan (Eds.), Case studies in spatial point process models (pp. 320). London: Springer Verlag.

Chapter

2005

Prevalence and genetic diversity of <i>Campylobacter</i> spp. in environmental water samples from a 100-square-kilometer predominantly dairy farming area

Kemp, R., Leatherbarrow, A. J. H., Williams, L. J., Hart, C. A., Clough, H. E., Turner, J., . . . French, N. P. (2005). Prevalence and genetic diversity of <i>Campylobacter</i> spp. in environmental water samples from a 100-square-kilometer predominantly dairy farming area. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(4), 1876-1882. doi:10.1128/AEM.71.4.1876-1882.2005

DOI
10.1128/AEM.71.4.1876-1882.2005
Journal article

Quantifying uncertainty associated with microbial count data: A Bayesian approach

Clough, H. E., Clancy, D., O'Neill, P. D., Robinson, S. E., & French, N. P. (2005). Quantifying uncertainty associated with microbial count data: A Bayesian approach. BIOMETRICS, 61(2), 610-616. doi:10.1111/j.1541-0420.2005.030903.x

DOI
10.1111/j.1541-0420.2005.030903.x
Journal article

2004

Frequency and spatial distribution of environmental <i>Campylobacter</i> spp.

Brown, P. E., Christensen, O. F., Clough, H. E., Diggle, P. J., Hart, C. A., Hazel, S., . . . French, N. P. (2004). Frequency and spatial distribution of environmental <i>Campylobacter</i> spp.. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(11), 6501-6511. doi:10.1128/AEM.70.11.6501-6511.2004

DOI
10.1128/AEM.70.11.6501-6511.2004
Journal article

It Shouldn't Happen to a Statistician

Clough, H., & Brown, P. (2004). It Shouldn't Happen to a Statistician. Significance, 1(3), 118-120. doi:10.1111/j.1740-9713.2004.00044.x

DOI
10.1111/j.1740-9713.2004.00044.x
Journal article

Frequency and spatial distribution of environmental Campylobacter spp.

Brown, P. E., Christensen, O. F., Clough, H. E., Diggle, P. J., Hart, C. A., Hazel, S., . . . French, N. P. (2004). Frequency and spatial distribution of environmental Campylobacter spp.. Applied and. Environmental Microbiology, 70(11), 6501-6511. doi:10.1128/AEM.70.11.6501¿6511.2004

DOI
10.1128/AEM.70.11.6501¿6511.2004
Journal article

2003

Bayesian methods for estimating pathogen prevalence within groups of animals from faecal-pat sampling (vol 58, pg 145, 2003)

Clough, H. E., Clancy, D., O'Neill, P. D., & French, N. P. (2003). Bayesian methods for estimating pathogen prevalence within groups of animals from faecal-pat sampling (vol 58, pg 145, 2003). PREVENTIVE VETERINARY MEDICINE, 60(2), 193. doi:10.1016/S0167-5877(03)00124-7

DOI
10.1016/S0167-5877(03)00124-7
Journal article

Bayesian methods for estimating pathogen prevalence within groups of animals from faecal-pat sampling

Clough, H. E., Clancy, D., O'Neill, P. D., & French, N. P. (2003). Bayesian methods for estimating pathogen prevalence within groups of animals from faecal-pat sampling. PREVENTIVE VETERINARY MEDICINE, 58(3-4), 145-169. doi:10.1016/S0167-5877(03)00050-3

DOI
10.1016/S0167-5877(03)00050-3
Journal article

Bayesian methods for estimating pathogen prevalence within groups of animals from faecal-pat sampling.

Clough, H. E., Clancy, D., O'Neill, P. D., & French, N. P. (2003). Bayesian methods for estimating pathogen prevalence within groups of animals from faecal-pat sampling.. Preventive veterinary medicine, 58(3-4), 145-169. doi:10.1016/s0167-5877(03)00050-3

DOI
10.1016/s0167-5877(03)00050-3
Journal article

2002

Statistical issues in the assessment of the evidence for an interaction between factors in epilepsy trials

Williamson, P. R., Clough, H. E., Hutton, J. L., Marson, A. G., & Chadwick, D. W. (2002). Statistical issues in the assessment of the evidence for an interaction between factors in epilepsy trials. STATISTICS IN MEDICINE, 21(18), 2613-2622. doi:10.1002/sim.1044

DOI
10.1002/sim.1044
Journal article

Carbamazepine versus valproate monotherapy for epilepsy: A meta-analysis

Marson, A. G., Williamson, P. R., Clough, H., Hutton, J. L., & Chadwick, D. W. (2002). Carbamazepine versus valproate monotherapy for epilepsy: A meta-analysis. EPILEPSIA, 43(5), 505-513. doi:10.1046/j.1528-1157.2002.20801.x

DOI
10.1046/j.1528-1157.2002.20801.x
Journal article

107. Persistence ofE. coli O157 on a Cheshire dairy farm

Robinson, S. E., Wright, J., French, N. P., Williams, N. J., Leatherbarrow, H., Sutherst, J., . . . Diggle, P. J. (2002). 107. Persistence ofE. coli O157 on a Cheshire dairy farm. Research in Veterinary Science, 72, 39. doi:10.1016/s0034-5288(02)90111-6

DOI
10.1016/s0034-5288(02)90111-6
Journal article

Carbamazepine versus phenytoin monotherapy for epilepsy.

Tudur Smith, C., Marson, A. G., Clough, H. E., & Williamson, P. R. (2002). Carbamazepine versus phenytoin monotherapy for epilepsy.. The Cochrane database of systematic reviews, (2), CD001911. doi:10.1002/14651858.cd001911

DOI
10.1002/14651858.cd001911
Journal article

2001

Carbamazepine versus valproate monotherapy for epilepsy

Marson, A. G., Williamson, P. R., Hutton, J. L., Clough, H. E., & Chadwick, D. W. (2001). Carbamazepine versus valproate monotherapy for epilepsy. Praxis, 90(37), 1595.

Journal article

2000

A comparison between parametric and non-parametric approaches to the analysis of replicated spatial point patterns

Diggle, P. J., Mateu, J., & Clough, H. E. (2000). A comparison between parametric and non-parametric approaches to the analysis of replicated spatial point patterns. Advances in Applied Probability, 32(02), 331-343. doi:10.1017/s0001867800009952

DOI
10.1017/s0001867800009952
Journal article

A comparison between parametric and non-parametric approaches to the analysis of replicated spatial point patterns

Diggle, P. J., Mateu, J., & Clough, H. E. (2000). A comparison between parametric and non-parametric approaches to the analysis of replicated spatial point patterns. Advances in Applied Probability, 32(2), 331-343. doi:10.1239/aap/1013540166

DOI
10.1239/aap/1013540166
Journal article

Carbamazepine versus valproate monotherapy for epilepsy.

Marson, A. G., Williamson, P. R., Hutton, J. L., Clough, H. E., & Chadwick, D. W. (2000). Carbamazepine versus valproate monotherapy for epilepsy.. The Cochrane database of systematic reviews, (3), CD001030. doi:10.1002/14651858.cd001030

DOI
10.1002/14651858.cd001030
Journal article

1998

Statistical Analysis of Replicated Spatial Point Patterns

Wilson, H. E. (1998). Statistical Analysis of Replicated Spatial Point Patterns. (PhD Thesis, The University of Lancaster).

Thesis / Dissertation

1996

Variations in price elasticities

George, J., Mercer, A., & Wilson, H. (1996). Variations in price elasticities. European Journal of Operational Research, 88(1), 13-22.

Journal article