Publications
Selected publications
- Pathogenic <i>Neisseria</i> Bind the Complement Protein CFHR5 <i>via</i> Outer Membrane Porins. (Journal article - 2022)
- Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis. (Journal article - 2021)
- Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility. (Journal article - 2014)
2024
Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design.
Jones, R. A., Ramirez-Bencomo, F., Whiting, G., Fang, M., Lavender, H., Kurzyp, K., . . . Tang, C. M. (2024). Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design.. PLoS pathogens, 20(11), e1012688. doi:10.1371/journal.ppat.1012688
2023
Meningococcal factor H-binding protein: implications for disease susceptibility, virulence, and vaccines.
Yee, W. -X., Barnes, G., Lavender, H., & Tang, C. M. (2023). Meningococcal factor H-binding protein: implications for disease susceptibility, virulence, and vaccines.. Trends in microbiology, 31(8), 805-815. doi:10.1016/j.tim.2023.02.011
2022
Pathogenic <i>Neisseria</i> Bind the Complement Protein CFHR5 <i>via</i> Outer Membrane Porins.
Yee, W. -X., Tang, C. M., & Lavender, H. (2022). Pathogenic <i>Neisseria</i> Bind the Complement Protein CFHR5 <i>via</i> Outer Membrane Porins.. Infection and immunity, 90(10), e0037722. doi:10.1128/iai.00377-22
2021
Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis.
Earle, S. G., Lobanovska, M., Lavender, H., Tang, C., Exley, R. M., Ramos-Sevillano, E., . . . Maiden, M. C. J. (2021). Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis.. PLoS pathogens, 17(10), e1009992. doi:10.1371/journal.ppat.1009992
Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup C <i>Neisseria meningitidis</i> isolate from cerebrospinal fluid of a patient with invasive meningococcal disease.
Facchetti, A., Wheeler, J. X., Vipond, C., Whiting, G., Lavender, H., Feavers, I. M., . . . Maharjan, S. (2021). Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup C <i>Neisseria meningitidis</i> isolate from cerebrospinal fluid of a patient with invasive meningococcal disease.. Access microbiology, 3(9), 000255. doi:10.1099/acmi.0.000255
2019
Versatile Electrochemical Sensing Platform for Bacteria.
Kuss, S., Couto, R. A. S., Evans, R. M., Lavender, H., Tang, C. C., & Compton, R. G. (2019). Versatile Electrochemical Sensing Platform for Bacteria.. Analytical chemistry, 91(7), 4317-4322. doi:10.1021/acs.analchem.9b00326
2017
Neisseria cinerea Expresses a Functional Factor H Binding Protein Which Is Recognized by Immune Responses Elicited by Meningococcal Vaccines.
Lavender, H., Poncin, K., & Tang, C. M. (2017). Neisseria cinerea Expresses a Functional Factor H Binding Protein Which Is Recognized by Immune Responses Elicited by Meningococcal Vaccines.. Infection and immunity, 85(10), e00305-e00317. doi:10.1128/iai.00305-17
2016
Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis.
Barnwal, R. P., Loh, E., Godin, K. S., Yip, J., Lavender, H., Tang, C. M., & Varani, G. (2016). Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis.. Nucleic acids research, 44(19), 9426-9437. doi:10.1093/nar/gkw584
Thermoregulation of Meningococcal fHbp, an Important Virulence Factor and Vaccine Antigen, Is Mediated by Anti-ribosomal Binding Site Sequences in the Open Reading Frame.
Loh, E., Lavender, H., Tan, F., Tracy, A., & Tang, C. M. (2016). Thermoregulation of Meningococcal fHbp, an Important Virulence Factor and Vaccine Antigen, Is Mediated by Anti-ribosomal Binding Site Sequences in the Open Reading Frame.. PLoS pathogens, 12(8), e1005794. doi:10.1371/journal.ppat.1005794
2014
Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility.
Caesar, J. J. E., Lavender, H., Ward, P. N., Exley, R. M., Eaton, J., Chittock, E., . . . Lea, S. M. (2014). Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility.. eLife, 3. doi:10.7554/elife.04008
2013
Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein.
Jongerius, I., Lavender, H., Tan, L., Ruivo, N., Exley, R. M., Caesar, J. J. E., . . . Tang, C. M. (2013). Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein.. PLoS pathogens, 9(8), e1003528. doi:10.1371/journal.ppat.1003528
2012
NF-κB regulates MICA gene transcription in endothelial cell through a genetically inhibitable control site.
Lin, D., Lavender, H., Soilleux, E. J., & O'Callaghan, C. A. (2012). NF-κB regulates MICA gene transcription in endothelial cell through a genetically inhibitable control site.. The Journal of biological chemistry, 287(6), 4299-4310. doi:10.1074/jbc.m111.282152
Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts.
Bertram, S., Heurich, A., Lavender, H., Gierer, S., Danisch, S., Perin, P., . . . Soilleux, E. J. (2012). Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts.. PloS one, 7(4), e35876. doi:10.1371/journal.pone.0035876
2011
Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease.
Bertram, S., Glowacka, I., Müller, M. A., Lavender, H., Gnirss, K., Nehlmeier, I., . . . Pöhlmann, S. (2011). Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease.. Journal of virology, 85(24), 13363-13372. doi:10.1128/jvi.05300-11