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Research

Research Interest 1

Transepithelial signalling

Research grants

Four year PhD Programme (2008)

WELLCOME TRUST (UK)

October 2008 - December 2012

The endocrinology of the upper gastrointestinal tract.

MEDICAL RESEARCH COUNCIL

October 2003 - September 2008

Gut-brain signalling in man: modulation of the cholecystokinin-vagus nerve pathway.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

May 2003 - September 2006

Nutrient modulation of vagal afferent signalling.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

September 2006 - August 2009

Nanoscale characterisation of cell surface signalling domains.

ROYAL SOCIETY

October 2003 - September 2008

Investigation of the genetic regulation of apoptosis in the stomach, with particular reference to the development of gastric atrophy.

WELLCOME TRUST (UK)

September 2002 - December 2007

Gut-Brain Signalling: Roles of Lipid, Cholecystokinin and the Vagus Nerve in Man.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

October 1999 - October 2002

Role of MMP-7 in the pathogenesis of gastric cancer.

NORTH WEST CANCER RESEARCH FUND

November 2003 - November 2006

Myofibroblast control of oesophageal squamous cancer invasion: role of chemerin

NORTH WEST CANCER RESEARCH FUND, NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

February 2015 - December 2018

The role of the vagus nerve in nutrient signalling from the gut to the brain.

MEDICAL RESEARCH COUNCIL

March 2002 - February 2004

The neuroendocrinology of the upper gastrointestinal tract

MEDICAL RESEARCH COUNCIL

October 1998 - September 2003

The role of Reg and its putative receptor EXTL3 in the gastric epithelium.

WELLCOME TRUST (UK)

October 1999 - September 2003

Wellcome Trust 3 year PhD - cellular and molecular physiology

WELLCOME TRUST (UK)

October 2010 - September 2013

Cellular biology of the gastrointestinal tract and pancreas in health and disease.

MEDICAL RESEARCH COUNCIL

January 2005 - December 2009

Cellular Biology of the Gastrointestinal Tract and Pancreas in Health and Disease.

MEDICAL RESEARCH COUNCIL

January 2000 - December 2004

Four year PhD Programme in Cellular and Molecular Physiology.

WELLCOME TRUST (UK)

October 2003 - September 2007

Identification of molecular mechanisms involved in the signalling of NMDA receptors to Ras.

WELLCOME TRUST (UK)

October 2001 - September 2006

Bridging and accelerating the translation of novel scientific findings for health and wealth gain

MEDICAL RESEARCH COUNCIL

March 2014 - August 2015

Actions of cholecystokinin on vagal afferent neurons

WELLCOME TRUST (UK)

December 2009 - January 2013

Mechanisms of promotion of colorectal carcinogenesis by the non-amidated precursors of gastrin in vitro and in vivo.

NORTH WEST CANCER RESEARCH FUND

January 2001 - August 2004

Modulation of gut-brain signalling: CCK effects on nodose ganglion neurones.

WELLCOME TRUST (UK)

October 2002 - September 2006

Four year PhD Programme in Cellular and Molecular Physiology.

WELLCOME TRUST (UK)

October 2000 - November 2004

Quantitative high-throughput proteomics for biomedical research.

MEDICAL RESEARCH COUNCIL

March 2005 - March 2008

Application of automated, high-content, live-cell, fluorescence imaging in multidisciplinary studies of epithelial, neuronal and stem cell function.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

April 2007 - March 2008

Intracellular and extracellular regulation of epithelial cell function in the gastrointestinal tract and pancreas.

WELLCOME TRUST (UK)

April 2000 - September 2003

    Research collaborations

    Professor David Thompson

    The University of Manchester

    Continuous collaboration since 1995 on gut-brain signalling, mostly supported by BBSRC

    Profs Dockray, Varro and Dimaline

    Profs Dockray, Varro, and Dimaline

    Collaboration on role of gastrin in gastrointestinal physiology