Publications
2025
Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,000 individuals.
Gonçalves, R., Blaauwendraad, S., Avraam, D., Beneíto, A., Charles, M. -A., Elhakeem, A., . . . Jaddoe, V. W. V. (2025). Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,000 individuals.. The Lancet regional health. Europe, 52, 101247. doi:10.1016/j.lanepe.2025.101247
Prevalence of Obesity Among Elementary School Children in Cyprus: The National COSI Program.
Markidou, E., Economidou, E. C., Avraam, D., Hassapidou, M., Hadjiminas, J. M., & Soteriades, E. S. (2025). Prevalence of Obesity Among Elementary School Children in Cyprus: The National COSI Program.. Nutrients, 17(7), 1213. doi:10.3390/nu17071213
The impact of contact-network structure on important epidemiological quantities of infectious disease transmission and the identification of the extremes.
Avraam, D., & Hadjichrysanthou, C. (2025). The impact of contact-network structure on important epidemiological quantities of infectious disease transmission and the identification of the extremes.. Journal of Theoretical Biology, 599. doi:10.1016/j.jtbi.2024.112010
dsTidyverse: An implementation of Tidyverse within the DataSHIELD ecosystem
Is maternal diabetes during pregnancy associated with neurodevelopmental, cognitive and behavioural outcomes in children? Insights from individual participant data meta-analysis in ten birth cohorts.
Pretorius, R. A., Avraam, D., Guxens, M., Julvez, J., Harris, J. R., Nader, J. T., . . . Huang, R. -C. (2025). Is maternal diabetes during pregnancy associated with neurodevelopmental, cognitive and behavioural outcomes in children? Insights from individual participant data meta-analysis in ten birth cohorts.. BMC pediatrics, 25(1), 76. doi:10.1186/s12887-024-05365-y
2024
DataSHIELD: mitigating disclosure risk in a multi-site federated analysis platform
Avraam, D., Wilson, R. C., Aguirre Chan, N., Banerjee, S., Bishop, T. R. P., Butters, O., . . . Burton, P. (2024). DataSHIELD: mitigating disclosure risk in a multi-site federated analysis platform. Bioinformatics Advances, 5(1). doi:10.1093/bioadv/vbaf046
MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD.
Cadman, T., Slofstra, M. K., van der Geest, M. A., Avraam, D., Bishop, T. R. P., de Boer, T., . . . Swertz, M. (2024). MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD.. Bioinformatics (Oxford, England), 41(1), btae726. doi:10.1093/bioinformatics/btae726
Federated privacy-protected meta- and mega-omics data analysis in multi-center studies with a fully open-source analytic platform.
Escriba-Montagut, X., Marcon, Y., Anguita-Ruiz, A., Avraam, D., Urquiza, J., Morgan, A. S., . . . Gonzalez, J. R. (2024). Federated privacy-protected meta- and mega-omics data analysis in multi-center studies with a fully open-source analytic platform.. PLoS computational biology, 20(12), e1012626. doi:10.1371/journal.pcbi.1012626
MOLGENIS Armadillo: a lightweight server for federated analysis using DataSHIELD
Social inequalities in child mental health trajectories: a longitudinal study using birth cohort data 12 countries.
Cadman, T., Avraam, D., Carson, J., Elhakeem, A., Grote, V., Guerlich, K., . . . Strandberg-Larsen, K. (2024). Social inequalities in child mental health trajectories: a longitudinal study using birth cohort data 12 countries.. BMC public health, 24(1), 2930. doi:10.1186/s12889-024-20291-5
Psychosocial Factors in Evidence-based Management Interventions and Policymaking: The COPSOQ III Greek Validation Study
Early childcare arrangements and children's internalizing and externalizing symptoms: an individual participant data meta-analysis of six prospective birth cohorts in Europe.
Barry, K. M., Avraam, D., Cadman, T., Elhakeem, A., El Marroun, H., Jansen, P. W., . . . Melchior, M. (2024). Early childcare arrangements and children's internalizing and externalizing symptoms: an individual participant data meta-analysis of six prospective birth cohorts in Europe.. The Lancet regional health. Europe, 45, 101036. doi:10.1016/j.lanepe.2024.101036
Late Breaking Abstract - Prediction of asthma in early-life: an individual participant data meta-analysis of 135,000 European and Australian children.
Karramass, T., Avraam, D., Van Klaveren, D., Ballester, F., Barros, H., Corpeleijn, E., . . . Duijts, L. (2024). Late Breaking Abstract - Prediction of asthma in early-life: an individual participant data meta-analysis of 135,000 European and Australian children.. In Paediatric asthma and allergy (pp. PA1343). European Respiratory Society. doi:10.1183/13993003.congress-2024.pa1343
Psychosocial Factors in Evidence-based Management Interventions and Policymaking: The COPSOQ III Greek Validation Study
Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes: An individual-participant data meta-analysis of >35.000 European children.
Fernandes, A., Avraam, D., Cadman, T., Dadvand, P., Guxens, M., Binter, A. -C., . . . Vrijheid, M. (2024). Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes: An individual-participant data meta-analysis of >35.000 European children.. Environment international, 190, 108853. doi:10.1016/j.envint.2024.108853
OP05 Understanding social inequalities in childhood asthma: quantifying the mediating role of modifiable early-life risk factors in seven birth cohorts in the EU Child cohort network
Pinot de Moira, A., Aurup, A. V., Avraam, D., Zugna, D., Jensen, A. K. G., Welten, M., . . . Elhakeem, A. (2024). OP05 Understanding social inequalities in childhood asthma: quantifying the mediating role of modifiable early-life risk factors in seven birth cohorts in the EU Child cohort network. In SSM Annual Scientific Meeting (pp. A3.1-A3). BMJ Publishing Group Ltd. doi:10.1136/jech-2024-ssmabstracts.5
Psychosocial Factors in Evidence-based Management Interventions and Policymaking: The COPSOQ III Greek Validation Study
Stress and anxiety during pregnancy and length of gestation: a federated study using data from five Canadian and European birth cohorts.
Bergeron, J., Avraam, D., Calas, L., Fraser, W., Harris, J. R., Heude, B., . . . Andersen, A. -M. N. (2024). Stress and anxiety during pregnancy and length of gestation: a federated study using data from five Canadian and European birth cohorts.. European journal of epidemiology, 39(7), 773-783. doi:10.1007/s10654-024-01126-4
Associations of Maternal Educational Level, Proximity to Green Space During Pregnancy, and Gestational Diabetes With Body Mass Index From Infancy to Early Adulthood: A Proof-of-Concept Federated Analysis in 18 Birth Cohorts.
Cadman, T., Elhakeem, A., Vinther, J. L., Avraam, D., Carrasco, P., Calas, L., . . . Lawlor, D. (2024). Associations of Maternal Educational Level, Proximity to Green Space During Pregnancy, and Gestational Diabetes With Body Mass Index From Infancy to Early Adulthood: A Proof-of-Concept Federated Analysis in 18 Birth Cohorts.. American journal of epidemiology, 193(5), 753-763. doi:10.1093/aje/kwad206
Leadership and Job satisfaction among Physicians in the Public Health Sector of Cyprus
Addressing Thalassaemia Management from Patients' Perspectives: An International Collaborative Assessment.
Economidou, E. C., Angastiniotis, M., Avraam, D., Soteriades, E. S., & Eleftheriou, A. (2024). Addressing Thalassaemia Management from Patients' Perspectives: An International Collaborative Assessment.. Medicina (Kaunas, Lithuania), 60(4), 650. doi:10.3390/medicina60040650
Non-parental childcare attendance prior to school entry and children’s internalising and externalising symptoms: an individual participant data meta-analysis of six child cohort studies (EU Child Cohort Network)
Addressing Thalassaemia Management from a Patients’ Perspective: an International Collaborative Assessment
Sleep duration in preschool age and later behavioral and cognitive outcomes: an individual participant data meta-analysis in five European cohorts.
Guerlich, K., Avraam, D., Cadman, T., Calas, L., Charles, M. -A., Elhakeem, A., . . . Plancoulaine, S. (2024). Sleep duration in preschool age and later behavioral and cognitive outcomes: an individual participant data meta-analysis in five European cohorts.. European child & adolescent psychiatry, 33(1), 167-177. doi:10.1007/s00787-023-02149-0
2023
Lifestyle patterns in European preschoolers: Associations with socio-demographic factors and body mass index.
Descarpentrie, A., Calas, L., Cornet, M., Heude, B., Charles, M. -A., Avraam, D., . . . Lioret, S. (2023). Lifestyle patterns in European preschoolers: Associations with socio-demographic factors and body mass index.. Pediatric obesity, 18(12), e13079. doi:10.1111/ijpo.13079
Leadership and Intention to Leave Among Public Health Sector Physicians in Cyprus: A National Cross-Sectional Study.
Gregoriou, I., Economidou, E. C., Avraam, D., Soteriades, E. S., Papastavrou, E., Charalambous, A., . . . Merkouris, A. (2023). Leadership and Intention to Leave Among Public Health Sector Physicians in Cyprus: A National Cross-Sectional Study.. In Studies in health technology and informatics Vol. 305 (pp. 89-92). doi:10.3233/shti230431
Neglecting complex network structures underestimates delays in a large-capital project
Ellinas, C., Avraam, D., & Nicolaides, C. (2023). Neglecting complex network structures underestimates delays in a large-capital project. Journal of Physics: Complexity, 4(2), 02LT01. doi:10.1088/2632-072x/accef0
Correction: Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies.
Vinther, J. L., Cadman, T., Avraam, D., Ekstrøm, C. T., Sørensen, T. I. A., Elhakeem, A., . . . Nybo Andersen, A. -M. (2023). Correction: Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies.. PLoS medicine, 20(4), e1004232. doi:10.1371/journal.pmed.1004232
Software Application Profile: ShinyDataSHIELD—an R Shiny application to perform federated non-disclosive data analysis in multicohort studies
Escribà-Montagut, X., Marcon, Y., Avraam, D., Banerjee, S., Bishop, T. R. P., Burton, P., & González, J. R. (2023). Software Application Profile: ShinyDataSHIELD—an R Shiny application to perform federated non-disclosive data analysis in multicohort studies. International Journal of Epidemiology, 52(1), 315-320. doi:10.1093/ije/dyac201
Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies.
Vinther, J. L., Cadman, T., Avraam, D., Ekstrøm, C. T., I A Sørensen, T., Elhakeem, A., . . . Nybo Andersen, A. -M. (2023). Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies.. PLoS medicine, 20(1), e1004036. doi:10.1371/journal.pmed.1004036
2022
Exposure to natural environments during pregnancy and birth outcomes in 11 European birth cohorts.
Torres Toda, M., Avraam, D., James Cadman, T., Fossati, S., de Castro, M., Dedele, A., . . . Dadvand, P. (2022). Exposure to natural environments during pregnancy and birth outcomes in 11 European birth cohorts.. Environment international, 170, 107648. doi:10.1016/j.envint.2022.107648
Ambient air pollution and body-mass index from infancy to later childhood in 10 European birth cohorts
Fossati, S., Marquez, S., Avraam, D., Cadman, T., Haakma, S., Andrusaityte, S., . . . Vrijheid, M. (2022). Ambient air pollution and body-mass index from infancy to later childhood in 10 European birth cohorts. ISEE Conference Abstracts, 2022(1). doi:10.1289/isee.2022.p-0493
Associations of maternal education, area deprivation, proximity to greenspace during pregnancy and gestational diabetes with Body Mass Index from early childhood to early adulthood: A proof-of-concept federated analysis in seventeen birth cohorts
Associations of early-life pet ownership with asthma and allergic sensitization: A meta-analysis of more than 77,000 children from the EU Child Cohort Network.
Pinot de Moira, A., Strandberg-Larsen, K., Bishop, T., Pedersen, M., Avraam, D., Cadman, T., . . . Nybo Andersen, A. -M. (2022). Associations of early-life pet ownership with asthma and allergic sensitization: A meta-analysis of more than 77,000 children from the EU Child Cohort Network.. The Journal of allergy and clinical immunology, 150(1), 82-92. doi:10.1016/j.jaci.2022.01.023
dsSurvival: Privacy preserving survival models for federated individual patient meta-analysis in DataSHIELD.
Banerjee, S., Sofack, G. N., Papakonstantinou, T., Avraam, D., Burton, P., Zöller, D., & Bishop, T. R. P. (2022). dsSurvival: Privacy preserving survival models for federated individual patient meta-analysis in DataSHIELD.. BMC research notes, 15(1), 197. doi:10.1186/s13104-022-06085-1
Mortality in Cyprus Over the Period 2016-2021.
Avraam, D., Economidou, E. C., Kountouras, J., Doulberis, M., & Soteriades, E. S. (2022). Mortality in Cyprus Over the Period 2016-2021.. Cureus, 14(4), e24325. doi:10.7759/cureus.24325
A deterministic approach for protecting privacy in sensitive personal data
Avraam, D., Jones, E., & Burton, P. (2022). A deterministic approach for protecting privacy in sensitive personal data. BMC MEDICAL INFORMATICS AND DECISION MAKING, 22(1). doi:10.1186/s12911-022-01754-4
dsSurvival: Privacy preserving survival models for federated individual patient meta-analysis in DataSHIELD
2021
Privacy preserving data visualizations
Avraam, D., Wilson, R., Butters, O., Burton, T., Nicolaides, C., Jones, E., . . . Burton, P. (2021). Privacy preserving data visualizations. EPJ DATA SCIENCE, 10(1). doi:10.1140/epjds/s13688-020-00257-4
The network limits of infectious disease control via occupation-based targeting.
Avraam, D., Obradovich, N., Pescetelli, N., Cebrian, M., & Rutherford, A. (2021). The network limits of infectious disease control via occupation-based targeting.. Scientific reports, 11(1), 22855. doi:10.1038/s41598-021-02226-x
Advancing tools for human early lifecourse exposome research and translation (ATHLETE)
Vrijheid, M., Basagana, X., Gonzalez, J. R., Jaddoe, V. W. V., Jensen, G., Keun, H. C., . . . Slama, R. (2021). Advancing tools for human early lifecourse exposome research and translation (ATHLETE). ENVIRONMENTAL EPIDEMIOLOGY, 5(5). doi:10.1097/EE9.0000000000000166
Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies.
Pinart, M., Jeran, S., Boeing, H., Stelmach-Mardas, M., Standl, M., Schulz, H., . . . Nimptsch, K. (2021). Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies.. The Journal of nutrition, 151(8), 2317-2329. doi:10.1093/jn/nxab077
A Deterministic Approach for Protecting Privacy in Sensitive Personal Data
The Network Limits of Infectious Disease Control via Occupation-Based Targeting
Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD
Marcon, Y., Bishop, T., Avraam, D., Escriba-Montagut, X., Ryser-Welch, P., Wheater, S., . . . Gonzalez, J. R. (2021). Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD. PLOS COMPUTATIONAL BIOLOGY, 17(3). doi:10.1371/journal.pcbi.1008880
2020
Pet ownership and allergic sensitisation and asthma in childhood: findings from the EU Child Cohort Network
Pinot de Moira, A., Strandberg-Larsen, K., Van Meel, E., Mensink-Bout, R., Popovic, M., Cadman, T., . . . Duijts, L. (2020). Pet ownership and allergic sensitisation and asthma in childhood: findings from the EU Child Cohort Network. In Epidemiology (pp. 435). European Respiratory Society. doi:10.1183/13993003.congress-2020.435
Hand-Hygiene Mitigation Strategies Against Global Disease Spreading through the Air Transportation Network
Nicolaides, C., Avraam, D., Cueto-Felgueroso, L., Gonzalez, M. C., & Juanes, R. (2020). Hand-Hygiene Mitigation Strategies Against Global Disease Spreading through the Air Transportation Network. RISK ANALYSIS, 40(4), 723-740. doi:10.1111/risa.13438
Breaking barriers for women in science
2019
Hand-hygiene mitigation strategies against global disease spreading through the air transportation network
2018
A software package for the application of probabilistic anonymisation to sensitive individual-level data: a proof of principle with an example from the ALSPAC birth cohort study
Avraam, D., Boyd, A., Goldstein, H., & Burton, P. (2018). A software package for the application of probabilistic anonymisation to sensitive individual-level data: a proof of principle with an example from the ALSPAC birth cohort study. LONGITUDINAL AND LIFE COURSE STUDIES, 9(4), 433-446. doi:10.14301/llcs.v9i4.478
2017
Universal statistics of epithelial tissue topology
Universal statistics of epithelial tissue topology
Abdullah, A., Avraam, D., Chepizhko, O., Vaccari, T., Zapperi, S., Porta, C. A. M. L., & Vasiev, B. (2017). Universal statistics of epithelial tissue topology. Retrieved from http://arxiv.org/abs/1710.08527v1
DataSHIELD – New Directions and Dimensions
Wilson, R. C., Butters, O. W., Avraam, D., Baker, J., Tedds, J. A., Turner, A., . . . Burton, P. R. (2017). DataSHIELD – New Directions and Dimensions. Data Science Journal, 16. doi:10.5334/dsj-2017-021
Privacy protected graphical functionality in DataSHIELD
Avraam, D., Gaye, A., Isaeva, J., Burton, T., Wilson, R., Turner, A., & Burton, P. (n.d.). Privacy protected graphical functionality in DataSHIELD. International Journal of Population Data Science, 1(1). doi:10.23889/ijpds.v1i1.296
Privacy protected text analysis in DataSHIELD
Wilson, R., Butters, O., Avraam, D., Turner, A., & Burton, P. (n.d.). Privacy protected text analysis in DataSHIELD. International Journal of Population Data Science, 1(1). doi:10.23889/ijpds.v1i1.289
Synthetic ALSPAC longitudinal datasets for the Big Data VR project.
Avraam, D., Wilson, R. C., & Burton, P. (2017). Synthetic ALSPAC longitudinal datasets for the Big Data VR project.. Wellcome open research, 2, 74. doi:10.12688/wellcomeopenres.12441.1
2016
On the heterogeneity of human populations as reflected by mortality dynamics
Avraam, D., Arnold, S., Vasieva, O., & Vasiev, B. (2016). On the heterogeneity of human populations as reflected by mortality dynamics. AGING-US, 8(11), 3045-3064. doi:10.18632/aging.101112
2015
Mathematical Study of Mortality Dynamics in Heterogeneous Population Composed of Subpopulations Following the Exponential Law
Arnold (-Gaille), S., Vasiev, B., Avraam, D., & de Magalhaes, J. P. (2015). Mathematical Study of Mortality Dynamics in Heterogeneous Population Composed of Subpopulations Following the Exponential Law.
2014
Time-evolution of age-dependent mortality patterns in mathematical model of heterogeneous human population
Avraam, D., Arnold-Gaille, S., Jones, D., & Vasiev, B. (2014). Time-evolution of age-dependent mortality patterns in mathematical model of heterogeneous human population. Experimental Gerontology, 60, 18-30. doi:10.1016/j.exger.2014.09.006
2013
A mathematical model of mortality dynamics across the lifespan combining heterogeneity and stochastic effects
Avraam, D., de Magalhaes, J. P., & Vasiev, B. (2013). A mathematical model of mortality dynamics across the lifespan combining heterogeneity and stochastic effects. EXPERIMENTAL GERONTOLOGY, 48(8), 801-811. doi:10.1016/j.exger.2013.05.054
Undated
Modelling mortality dynamics in heterogeneous human populations
Avraam, D. (n.d.). Modelling mortality dynamics in heterogeneous human populations. (PhD Thesis, University of Liverpool).
Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven Birth Cohorts in the EU Child Cohort Network
Pinot de Moira, A., Aurup, A. V., Avraam, D., Zugna, D., Jensen, A. K. G., Welten, M., . . . Andersen, A. -M. N. (n.d.). Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven Birth Cohorts in the EU Child Cohort Network.