Publications
Selected publications
- Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids (Journal article - 2018)
- Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids (Journal article - 2017)
- Brachyury cooperates with Wnt/beta-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells (Journal article - 2014)
- Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells (Journal article - 2014)
- Gastruloids develop the three body axes in the absence of extraembryonic tissues and spatially localised signalling (Journal article - 2017)
2024
SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesis.
Barter, M. J., Turner, D. A., Rice, S. J., Hines, M., Lin, H., Falconer, A. M. D., . . . Wilkinson, D. J. (2024). SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesis.. Matrix biology : journal of the International Society for Matrix Biology, S0945-053X(24)00095-7. doi:10.1016/j.matbio.2024.07.004
Human extravillous trophoblast organoids are permissive to human cytomegalovirus infection due to limited production of interferon type III
Radziun, K., Nevels, M., Turner, D. A., Kadioglu, A., & Yang, M. (2024). Human extravillous trophoblast organoids are permissive to human cytomegalovirus infection due to limited production of interferon type III. Placenta, 154, e3. doi:10.1016/j.placenta.2024.07.060
Three-dimensional stem cell models of mammalian gastrulation
Turner, D. A., & Martinez Arias, A. (2024). Three-dimensional stem cell models of mammalian gastrulation. BioEssays. doi:10.1002/bies.202400123
SERPINA3 (ALPHA-1 ANTICHYMOTRYPSIN) IS ESSENTIAL FOR EXTRACELLULAR MATRIX PRODUCTION DURING CARTILAGE FORMATION AND REGULATES THE CHONDROGENIC TRANSCRIPTION FACTOR SOX9
Barter, M. J., Turner, D. A., Rice, S. J., Hines, M., Lin, H., Falconer, A. M., . . . WILKINSON, D. J. (2024). SERPINA3 (ALPHA-1 ANTICHYMOTRYPSIN) IS ESSENTIAL FOR EXTRACELLULAR MATRIX PRODUCTION DURING CARTILAGE FORMATION AND REGULATES THE CHONDROGENIC TRANSCRIPTION FACTOR SOX9. Osteoarthritis and Cartilage, 32, S389. doi:10.1016/j.joca.2024.02.568
2023
Modifying gastruloids to dissect mechanisms of tissue-specific induction.
Turner, D. A., & Nichols, J. (2023). Modifying gastruloids to dissect mechanisms of tissue-specific induction.. Current opinion in genetics & development, 83, 102130. doi:10.1016/j.gde.2023.102130
Novel 3D in vitro human placenta-on-a-chip model derived using human trophoblast stem cells differentiated towards syncytiotrophoblasts and extravillous trophoblasts to mimic both villi and implantation sides of the placenta.
Radziun, K., Sharp, A., Aye, I., Turner, D., Kadioglu, A., & Yang, M. (2023). NOVEL 3D IN VITRO HUMAN PLACENTA-ON-A-CHIP MODEL DERIVED USING HUMAN TROPHOBLAST STEM CELLS DIFFERENTIATED TOWARDS SYNCYTIOTROPHOBLASTS AND EXTRAVILLOUS TROPHOBLASTS TO MIMIC BOTH VILLI AND IMPLANTATION SIDES OF THE PLACENTA. In PLACENTA Vol. 140 (pp. E27-E28). Retrieved from https://www.webofscience.com/
RNA binding protein HUR regulate osteoclast induction capacity of MG63 cells
Fu, S., Turner, D., & Tew, S. (2023). RNA binding protein HUR regulate osteoclast induction capacity of MG63 cells. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A5-A6). Retrieved from https://www.webofscience.com/
2021
Sculpting with stem cells: how models of embryo development take shape
Veenvliet, J. V., Lenne, P. -F., Turner, D. A., Nachman, I., & Trivedi, V. (2021). Sculpting with stem cells: how models of embryo development take shape. DEVELOPMENT, 148(24). doi:10.1242/dev.192914
Gastruloids: Embryonic Organoids from Mouse Embryonic Stem Cells to Study Patterning and Development in Early Mammalian Embryos
Anlas, K., Baillie-Benson, P., Arató, K., Turner, D., & Trivedi, V. (n.d.). Gastruloids: Embryonic Organoids from Mouse Embryonic Stem Cells to Study Patterning and Development in Early Mammalian Embryos. Methods in Molecular Biology, 2258, 131-147. doi:10.1007/978-1-0716-1174-6_10
2018
Generating Gastruloids from Mouse Embryonic Stem Cells
Beccari, L., Girgin, M., Turner, D. A., Baillie-Johnson, P., Cossy, A. -C., Beccari, L., . . . Martinez Arias, A. (n.d.). Generating Gastruloids from Mouse Embryonic Stem Cells. Protocol Exchange. doi:10.1038/protex.2018.094
Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids
Beccari, L., Moris, N., Girgin, M., Turner, D. A., Baillie-Johnson, P., Cossy, A. -C., . . . Martinez Arias, A. (2018). Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids. Nature, 562(7726), 272-276. doi:10.1038/s41586-018-0578-0
2017
Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids
Turner, D. A., Girgin, M., Alonso-Crisostomo, L., Trivedi, V., Baillie-Johnson, P., Glodowski, C. R., . . . Arias, A. M. (2017). Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids. DEVELOPMENT, 144(21), 3894-3906. doi:10.1242/dev.150391
From organoids to Gastruloids
Turner, D. A. (2017). From organoids to Gastruloids. Biologist, 64(5), 14-19. Retrieved from https://thebiologist.rsb.org.uk/
Gastruloids develop the three body axes in the absence of extraembryonic tissues and spatially localised signalling
Turner, D. A., Alonso-Crisostomo, L., Girgin, M., Baillie-Johnson, P., Glodowski, C. R., Hayward, P. C., . . . Martinez Arias, A. (2017). <i>Gastruloids</i> develop the three body axes in the absence of extraembryonic tissues and spatially localised signalling. doi:10.1101/104539
2016
Interactions between Nodal and Wnt signalling Drive Robust Symmetry-Breaking and Axial Organisation in<i>Gastruloids</i>(Embryonic Organoids)
Turner, D. A., Glodowski, C. R., Alonso-Crisostomo, L., Baillie-Johnson, P., Hayward, P. C., Collignon, J., . . . Martinez Arias, A. (2016). Interactions between Nodal and Wnt signalling Drive Robust Symmetry-Breaking and Axial Organisation in<i>Gastruloids</i>(Embryonic Organoids). doi:10.1101/051722
Organoids and the genetically encoded self-assembly of embryonic stem cells
Turner, D. A., Baillie-Johnson, P., & Arias, A. M. (2016). Organoids and the genetically encoded self-assembly of embryonic stem cells. BIOESSAYS, 38(2), 181-191. doi:10.1002/bies.201500111
2015
Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour <em>In Vitro</em>
Baillie-Johnson, P., van den Brink, S. C., Balayo, T., Turner, D. A., & Martinez Arias, A. (n.d.). Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour <em>In Vitro</em>. Journal of Visualized Experiments, (105). doi:10.3791/53252-v
Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro.
Baillie-Johnson, P., van den Brink, S. C., Balayo, T., Turner, D. A., & Martinez Arias, A. (2015). Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro.. Journal of visualized experiments : JoVE, (105). doi:10.3791/53252
2014
Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells
van den Brink, S. C., Baillie-Johnson, P., Balayo, T., Hadjantonakis, A. -K., Nowotschin, S., Turner, D. A., & Arias, A. M. (2014). Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells. DEVELOPMENT, 141(22), 4231-4242. doi:10.1242/dev.113001
Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells
Turner, D. A., Hayward, P. C., Baillie-Johnson, P., Rue, P., Broome, R., Faunes, F., & Arias, A. M. (2014). Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells. Development, 141(22), 4243-4253. doi:10.1242/dev.112979
Brachyury cooperates with Wnt/beta-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells
Turner, D. A., Rue, P., Mackenzie, J. P., Davies, E., & Arias, A. M. (2014). Brachyury cooperates with Wnt/beta-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells. BMC BIOLOGY, 12. doi:10.1186/s12915-014-0063-7
An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells
Turner, D. A., Trott, J., Hayward, P., Rue, P., & Arias, A. M. (2014). An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells. BIOLOGY OPEN, 3(7), 614-626. doi:10.1242/bio.20148409
Generation of Aggregates of Mouse ES Cells that Show Symmetry Breaking, Polarisation and Emergent Collective Behaviour<i>in vitro</i>
Brachyury cooperates with Wnt/β-Catenin signalling to elicit Primitive Streak like behaviour in differentiating mouse ES cells.
2013
An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells
2010
An Investigation into the Dynamics of NF-kappaB Following Physiological Levels of Cytokine Stimulation in Single Living Cells
Turner, D. (2010, September). An Investigation into the Dynamics of NF-kappaB Following Physiological Levels of Cytokine Stimulation in Single Living Cells.
Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells
Turner, D. A., Paszek, P., Woodcock, D. J., Nelson, D. E., Horton, C. A., Wang, Y., . . . Harper, C. V. (2010). Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells. JOURNAL OF CELL SCIENCE, 123(16), 2834-2843. doi:10.1242/jcs.069641
2009
Information management for high content live cell imaging
Jameson, D., Turner, D. A., Ankers, J., Kennedy, S., Ryan, S., Swainston, N., . . . Paton, N. W. (2009). Information management for high content live cell imaging. BMC BIOINFORMATICS, 10. doi:10.1186/1471-2105-10-226