Research
David’s research interests are in the field of maternal infection and immunity, the problem of recurrent miscarriage and global maternal health. His research seeks to improve the care of women during pregnancy and childbirth in low income countries include clinical trials, evidence synthesis, implementation research and policymaking. He has a specific interest in the prevention and management of maternal infection and sepsis in low resource settings. He has completed important multi-country clinical trials such as the AIMS (antibiotics in miscarriage surgery trial) published in the NEJM, and has an ongoing portfolio of studies in Malawi, Uganda and Pakistan.
Research grants
NIHR Global Health Research Group on Improving Quality of Maternal Healthcare in Africa
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
August 2022 - July 2026
PReparing for Optimal Phase III/IV maTErnal Group B StreptococCal vaccine Trials in Africa (PROTECT) (PROTECT)
UK RESEARCH AND INNOVATION
January 2024 - February 2027
Towards innovative management of maternal sepsis to tackle antimicrobial resistance in maternity care
UK HEALTH SECURITY AGENCY - UKHSA (UK)
January 2024 - March 2024
Strategies to reduce vertical transmission of multi-drug resistant pathogens (NeoVT-AMR)
MEDICAL RESEARCH COUNCIL
May 2020 - September 2022
Trained Immunity in BCG vaccinated children
SILICON VALLEY COMMUNITY FOUNDATION (USA)
October 2021 - April 2025
Stopping mothers dying from sepsis in Africa
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2021 - January 2026
An International World Health Organisation Collaboration to Implement and Evaluate at Scale the Active Prevention and Treatment of Maternal Sepsis (APT-Sepsis)
MEDICAL RESEARCH COUNCIL
February 2021 - October 2025