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2023

Prevalence of Potentially Clinically Significant Drug-Drug Interactions With Antiretrovirals Against HIV Over Three Decades: A Systematic Review of the Literature

Hodge, D., Hodel, E. M., Hughes, E., Hazenberg, P., Granana Castillo, S., Gibbons, S., . . . Khoo, S. (2023). Prevalence of Potentially Clinically Significant Drug-Drug Interactions With Antiretrovirals Against HIV Over Three Decades: A Systematic Review of the Literature. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 92(2), 97-105. doi:10.1097/QAI.0000000000003122

DOI
10.1097/QAI.0000000000003122
Journal article

2022

Recommendations for the Management of Drug-Drug Interactions Between the COVID-19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications

Marzolini, C., Kuritzkes, D. R., Marra, F., Boyle, A., Gibbons, S., Flexner, C., . . . Khoo, S. (2022). Recommendations for the Management of Drug-Drug Interactions Between the COVID-19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications. CLINICAL PHARMACOLOGY & THERAPEUTICS, 112(6), 1191-1200. doi:10.1002/cpt.2646

DOI
10.1002/cpt.2646
Journal article

Prescribing Nirmatrelvir-Ritonavir: How to Recognize and Manage Drug-Drug Interactions

Marzolini, C., Kuritzkes, D. R., Marra, F., Boyle, A., Gibbons, S., Flexner, C., . . . Khoo, S. (2022). Prescribing Nirmatrelvir-Ritonavir: How to Recognize and Manage Drug-Drug Interactions. ANNALS OF INTERNAL MEDICINE, 175(5), 744-+. doi:10.7326/M22-0281

DOI
10.7326/M22-0281
Journal article

Fluvoxamine for the treatment of COVID-19

Marzolini, C., Marra, F., Boyle, A., Khoo, S., & Back, D. J. (2022). Fluvoxamine for the treatment of COVID-19. LANCET GLOBAL HEALTH, 10(3), E331. Retrieved from https://www.webofscience.com/

Journal article

2021

The intersection of drug interactions and adverse reactions in contemporary antiretroviral therapy.

Nhean, S., Tseng, A., & Back, D. (2021). The intersection of drug interactions and adverse reactions in contemporary antiretroviral therapy.. Current opinion in HIV and AIDS, 16(6), 292-302. doi:10.1097/coh.0000000000000701

DOI
10.1097/coh.0000000000000701
Journal article

Prescribing in COVID-19 patients: Should we take into account inflammation?

Marzolini, C., Battegay, M., Sendi, P., & Back, D. J. (2021). Prescribing in COVID-19 patients: Should we take into account inflammation?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(3), 719-721. doi:10.1111/bcp.14524

DOI
10.1111/bcp.14524
Journal article

2020

Safety perspectives on presently considered drugs for the treatment of COVID‐19

Penman, S. L., Kiy, R. T., Jensen, R. L., Beoku‐Betts, C., Alfirevic, A., Back, D., . . . Chadwick, A. E. (n.d.). Safety perspectives on presently considered drugs for the treatment of COVID‐19. British Journal of Pharmacology. doi:10.1111/bph.15204

DOI
10.1111/bph.15204
Journal article

Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect

Stader, F., Khoo, S., Stoeckle, M., Back, D., Hirsch, H. H., Battegay, M., & Marzolini, C. (2020). Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75(10), 3084-3086. doi:10.1093/jac/dkaa253

DOI
10.1093/jac/dkaa253
Journal article

Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.

Arshad, U., Pertinez, H., Box, H., Tatham, L., Rajoli, R. K., Curley, P., . . . Owen, A. (2020). Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.. Clinical pharmacology and therapeutics. doi:10.1002/cpt.1909

DOI
10.1002/cpt.1909
Journal article

Drug–drug interactions with direct‐acting antivirals: when do we need to care?

Marra, F., & Back, D. (2020). Drug–drug interactions with direct‐acting antivirals: when do we need to care?. In Unknown Book (pp. 86-93). Wiley. doi:10.1002/9781119533481.ch15

DOI
10.1002/9781119533481.ch15
Chapter

2019

Real-world safety and effectiveness of ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in hepatitis C virus genotype 1-and 4-infected patients with diverse comorbidities and comedications: A pooled analysis of post-marketing observational studies from 13 countries

Ferenci, P., Bourgeois, S., Buggisch, P., Norris, S., Curescu, M., Larrey, D., . . . Flisiak, R. (2019). Real-world safety and effectiveness of ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in hepatitis C virus genotype 1-and 4-infected patients with diverse comorbidities and comedications: A pooled analysis of post-marketing observational studies from 13 countries. JOURNAL OF VIRAL HEPATITIS, 26(6), 685-696. doi:10.1111/jvh.13080

DOI
10.1111/jvh.13080
Journal article

Predicting Drug-Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling

Rajoli, R. K. R., Curley, P., Chiong, J., Back, D., Flexner, C., Owen, A., & Siccardi, M. (2019). Predicting Drug-Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling. JOURNAL OF INFECTIOUS DISEASES, 219(11), 1735-1742. doi:10.1093/infdis/jiy726

DOI
10.1093/infdis/jiy726
Journal article

Successful HCV treatment of patients on contraindicated anti-epileptic drugs: Role of drug level monitoring

van Seyen, M., Smolders, E. J., van Wijngaarden, P., Drenth, J. P. H., Wouthuyzen-Bakker, M., de Knegt, R. J., . . . Burger, D. M. (2019). Successful HCV treatment of patients on contraindicated anti-epileptic drugs: Role of drug level monitoring. JOURNAL OF HEPATOLOGY, 70(3), 552-554. doi:10.1016/j.jhep.2018.10.010

DOI
10.1016/j.jhep.2018.10.010
Journal article

Antiretroviral drug-drug interactions in an era of polypharmacy

Back, D. (2019). Antiretroviral drug-drug interactions in an era of polypharmacy. GERMS, 9(3), 123-124. doi:10.18683/germs.2019.1166.

DOI
10.18683/germs.2019.1166.
Journal article

2018

Widespread use of herbal medicines by people living with human immunodeficiency virus and contamination of herbal medicines with antiretrovirals in Nigeria.

Gini, J., Amara, A., Penchala, S. D., Back, D. J., Else, L., Egan, D., . . . Khoo, S. H. (2018). Widespread use of herbal medicines by people living with human immunodeficiency virus and contamination of herbal medicines with antiretrovirals in Nigeria.. International journal of STD & AIDS, 956462418809749. doi:10.1177/0956462418809749

DOI
10.1177/0956462418809749
Journal article

Clinical impact of pharmacokinetic interactions between the HCV protease inhibitor simeprevir and frequently used concomitant medications

Marra, F., zu Siederdissen, C. H., Khoo, S., Back, D., Schlag, M., Ouwerkerk-Mahadevan, S., . . . Cornberg, M. (2018). Clinical impact of pharmacokinetic interactions between the HCV protease inhibitor simeprevir and frequently used concomitant medications. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 84(5), 961-971. doi:10.1111/bcp.13519

DOI
10.1111/bcp.13519
Journal article

Development, validation and utilization of a highly sensitive LC-MS/MS method for quantification of levonorgestrel released from a subdermal implant in human plasma

Cirrincione, L. R., Penchala, S. D., Scarsi, K. K., Podany, A. T., Winchester, L. C., Back, D. J., . . . Else, L. J. (2018). Development, validation and utilization of a highly sensitive LC-MS/MS method for quantification of levonorgestrel released from a subdermal implant in human plasma. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1084, 106-112. doi:10.1016/j.jchromb.2018.03.023

DOI
10.1016/j.jchromb.2018.03.023
Journal article

Kidney Diseases Associated with Human Immunodeficiency Virus Infection

Back, D. J. (2018). Kidney Diseases Associated with Human Immunodeficiency Virus Infection. NEW ENGLAND JOURNAL OF MEDICINE, 378(17), 1654-+. Retrieved from https://www.webofscience.com/

Journal article

Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug–drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART

Roberts, O., Rajoli, R. K. R., Back, D. J., Owen, A., Darin, K. M., Fletcher, C. V., . . . Siccardi, M. (2018). Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug–drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART. Journal of Antimicrobial Chemotherapy, 73(4), 1004-1012. doi:10.1093/jac/dkx515

DOI
10.1093/jac/dkx515
Journal article

Pharmacokinetics and pharmacodynamics of the nucleoside sparing dual regimen containing rilpivirine plus darunavir/ritonavir in treatment-naïve HIV-1-infected individuals.

Jackson, A., Else, L., Higgs, C., Karolia, Z., Khoo, S., Back, D., . . . Boffito, M. (2018). Pharmacokinetics and pharmacodynamics of the nucleoside sparing dual regimen containing rilpivirine plus darunavir/ritonavir in treatment-naive HIV-1-infected individuals. HIV CLINICAL TRIALS, 19(1), 31-37. doi:10.1080/15284336.2017.1408928

DOI
10.1080/15284336.2017.1408928
Journal article

2017

A Call for a Consortium for Optimal Management of Drug-Drug Interactions in Patient Care

Burger, D. M., Smolders, E. J., Schapiro, J., Drenth, J. P. H., & Back, D. J. (2017). A Call for a Consortium for Optimal Management of Drug-Drug Interactions in Patient Care. CLINICAL PHARMACOLOGY & THERAPEUTICS, 102(3), 391-394. doi:10.1002/cpt.648

DOI
10.1002/cpt.648
Journal article

The Effect of Gene Variants on Levonorgestrel Pharmacokinetics When Combined With Antiretroviral Therapy Containing Efavirenz or Nevirapine

Neary, M., Lamorde, M., Olagunju, A., Darin, K. M., Merry, C., Byakika-Kibwika, P., . . . Scarsi, K. K. (2017). The Effect of Gene Variants on Levonorgestrel Pharmacokinetics When Combined With Antiretroviral Therapy Containing Efavirenz or Nevirapine. CLINICAL PHARMACOLOGY & THERAPEUTICS, 102(3), 529-536. doi:10.1002/cpt.667

DOI
10.1002/cpt.667
Journal article

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes

Marzolini, C., Rajoli, R., Battegay, M., Elzi, L., Back, D., & Siccardi, M. (2017). Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes. CLINICAL PHARMACOKINETICS, 56(4), 409-420. doi:10.1007/s40262-016-0447-7

DOI
10.1007/s40262-016-0447-7
Journal article

Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection

Seden, K., Gibbons, S., Marzolini, C., Schapiro, J. M., Burger, D. M., Back, D. J., & Khoo, S. H. (2017). Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection. PLOS ONE, 12(3). doi:10.1371/journal.pone.0173509

DOI
10.1371/journal.pone.0173509
Journal article

Use of a physiologically based pharmacokinetic model to simulate drug–drug interactions between antineoplastic and antiretroviral drugs

Molto, J., Rajoli, R., Back, D. J., Valle, M., Miranda, C., Owen, A., . . . Siccardi, M. (2017). Use of a physiologically based pharmacokinetic model to simulate drug–drug interactions between antineoplastic and antiretroviral drugs. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 72(3), 805-811. doi:10.1093/jac/dkw485

DOI
10.1093/jac/dkw485
Journal article

2-Drug regimens in HIV treatment: pharmacological considerations.

Back, D. (2017). 2-Drug regimens in HIV treatment: pharmacological considerations.. Germs, 7(3), 113-114. doi:10.18683/germs.2017.1115

DOI
10.18683/germs.2017.1115
Journal article

Comparison of Dried Blood Spots Versus Conventional Plasma Collection for the Characterization of Efavirenz Pharmacokinetics in a Large-Scale Global Clinical Trial-The ENCORE1 Study

Amara, A. B., Else, L. J., Carey, D., Khoo, S., Back, D. J., Amin, J., . . . Puls, R. L. (2017). Comparison of Dried Blood Spots Versus Conventional Plasma Collection for the Characterization of Efavirenz Pharmacokinetics in a Large-Scale Global Clinical Trial-The ENCORE1 Study. THERAPEUTIC DRUG MONITORING, 39(6), 654-658. doi:10.1097/FTD.0000000000000448

DOI
10.1097/FTD.0000000000000448
Journal article

2016

Challenges in treating patients with inflammatory bowel disease and concurrent viral hepatitis infection.

Degasperi, E., Caprioli, F., El Sherif, O., Back, D., Colombo, M., & Aghemo, A. (2016). Challenges in treating patients with inflammatory bowel disease and concurrent viral hepatitis infection.. Expert review of gastroenterology & hepatology, 10(12), 1373-1383. doi:10.1080/17474124.2016.1246181

DOI
10.1080/17474124.2016.1246181
Journal article

Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment

McGowan, I., Dezzutti, C. S., Siegel, A., Engstrom, J., Nikiforov, A., Duffill, K., . . . Cranston, R. D. (2016). Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment. LANCET HIV, 3(12), E569-E578. doi:10.1016/S2352-3018(16)30113-8

DOI
10.1016/S2352-3018(16)30113-8
Journal article

Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis.

Fox, J., Tiraboschi, J. M., Herrera, C., Else, L., Egan, D., Dickinson, L., . . . Boffito, M. (2016). Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis.. Journal of acquired immune deficiency syndromes (1999), 73(3), 252-257. doi:10.1097/qai.0000000000001108

DOI
10.1097/qai.0000000000001108
Journal article

Efavirenz and Metabolites in Cerebrospinal Fluid: Relationship with CYP2B6 c.516G -> T Genotype and Perturbed Blood-Brain Barrier Due to Tuberculous Meningitis

Nightingale, S., Chau, T. T. H., Fisher, M., Nelson, M., Winston, A., Else, L., . . . Grp, P. -V. S. (2016). Efavirenz and Metabolites in Cerebrospinal Fluid: Relationship with CYP2B6 c.516G -> T Genotype and Perturbed Blood-Brain Barrier Due to Tuberculous Meningitis. Antimicrobial Agents and Chemotherapy, 60(8), 4511-4518. doi:10.1128/AAC.00280-16

DOI
10.1128/AAC.00280-16
Journal article

Pregnancy affects nevirapine pharmacokinetics: evidence from a <i>CYP2B6</i> genotype-guided observational study

Olagunju, A., Bolaji, O., Neary, M., Back, D., Khoo, S., & Owen, A. (2016). Pregnancy affects nevirapine pharmacokinetics: evidence from a <i>CYP2B6</i> genotype-guided observational study. PHARMACOGENETICS AND GENOMICS, 26(8), 381-389. doi:10.1097/FPC.0000000000000227

DOI
10.1097/FPC.0000000000000227
Journal article

The development and application of a novel LC-MS/MS method for the measurement of Dolutegravir, Elvitegravir and Cobicistat in human plasma

Penchala, S. D., Fawcett, S., Else, L., Egan, D., Amara, A., Elliot, E., . . . Khoo, S. (2016). The development and application of a novel LC-MS/MS method for the measurement of Dolutegravir, Elvitegravir and Cobicistat in human plasma. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1027, 174-180. doi:10.1016/j.jchromb.2016.05.040

DOI
10.1016/j.jchromb.2016.05.040
Journal article

Cobicistat versus ritonavir boosting and differences in the drug-drug interaction profiles with co-medications

Marzolini, C., Gibbons, S., Khoo, S., & Back, D. (2016). Cobicistat versus ritonavir boosting and differences in the drug-drug interaction profiles with co-medications. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71(7), 1755-1758. doi:10.1093/jac/dkw032

DOI
10.1093/jac/dkw032
Journal article

Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naive HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study

Dickinson, L., Amin, J., Else, L., Boffito, M., Egan, D., Owen, A., . . . Puls, R. (2016). Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naive HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study. CLINICAL PHARMACOKINETICS, 55(7), 861-873. doi:10.1007/s40262-015-0360-5

DOI
10.1007/s40262-015-0360-5
Journal article

Distinct Pharmacodynamic Activity of Rilpivirine in Ectocervical and Colonic Explant Tissue

Dezzutti, C. S., Else, L. J., Yandura, S. E., Shetler, C., Russo, J., Back, D. J., & McGowan, I. (2016). Distinct Pharmacodynamic Activity of Rilpivirine in Ectocervical and Colonic Explant Tissue. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 60(5), 2765-2770. doi:10.1128/AAC.00167-16

DOI
10.1128/AAC.00167-16
Journal article

Dolutegravir and elvitegravir plasma concentrations following cessation of drug intake

Elliot, E., Amara, A., Jackson, A., Moyle, G., Else, L., Khoo, S., . . . Boffito, M. (2016). Dolutegravir and elvitegravir plasma concentrations following cessation of drug intake. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71(4), 1031-1036. doi:10.1093/jac/dkv425

DOI
10.1093/jac/dkv425
Journal article

Simulation of the impact of rifampicin on once-daily darunavir/ritonavir pharmacokinetics and dose adjustment strategies: a population pharmacokinetic approach

Dickinson, L., Winston, A., Boffito, M., Khoo, S., Back, D., & Siccardi, M. (2016). Simulation of the impact of rifampicin on once-daily darunavir/ritonavir pharmacokinetics and dose adjustment strategies: a population pharmacokinetic approach. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71(4), 1041-1045. doi:10.1093/jac/dkv439

DOI
10.1093/jac/dkv439
Journal article

Selection of Rilpivirine-Resistant HIV-1 in a Seroconverter From the SSAT 040 Trial Who Received the 300-mg Dose of Long-Acting Rilpivirine (TMC278LA).

Penrose, K. J., Parikh, U. M., Hamanishi, K. A., Else, L., Back, D., Boffito, M., . . . Mellors, J. W. (2016). Selection of Rilpivirine-Resistant HIV-1 in a Seroconverter From the SSAT 040 Trial Who Received the 300-mg Dose of Long-Acting Rilpivirine (TMC278LA).. The Journal of infectious diseases, 213(6), 1013-1017. doi:10.1093/infdis/jiv528

DOI
10.1093/infdis/jiv528
Journal article

Unintended Pregnancies Observed With Combined Use of the Levonorgestrel Contraceptive Implant and Efavirenz-based Antiretroviral Therapy: A Three-Arm Pharmacokinetic Evaluation Over 48 Weeks

Scarsi, K. K., Darin, K. M., Nakalema, S., Back, D. J., Byakika-Kibwika, P., Else, L. J., . . . Lamorde, M. (2016). Unintended Pregnancies Observed With Combined Use of the Levonorgestrel Contraceptive Implant and Efavirenz-based Antiretroviral Therapy: A Three-Arm Pharmacokinetic Evaluation Over 48 Weeks. CLINICAL INFECTIOUS DISEASES, 62(6), 675-682. doi:10.1093/cid/civ1001

DOI
10.1093/cid/civ1001
Journal article

Drug-Drug Interactions With Novel All Oral Interferon-Free Antiviral Agents in a Large Real-World Cohort

Siederdissen, C. H. Z., Maasoumy, B., Marra, F., Deterding, K., Port, K., Manns, M. P., . . . Wedemeyer, H. (2016). Drug-Drug Interactions With Novel All Oral Interferon-Free Antiviral Agents in a Large Real-World Cohort. CLINICAL INFECTIOUS DISEASES, 62(5), 561-567. doi:10.1093/cid/civ973

DOI
10.1093/cid/civ973
Journal article

Tenofovir Disoproxil Fumarate Fails to Prevent HIV Acquisition or the Establishment of a Viral Reservoir: Two Case Reports

Fox, J., Brady, M., Alexander, H., Davies, O., Robinson, N., Pace, M., . . . Frater, J. (2016). Tenofovir Disoproxil Fumarate Fails to Prevent HIV Acquisition or the Establishment of a Viral Reservoir: Two Case Reports. INFECTIOUS DISEASES AND THERAPY, 5(1), 65-71. doi:10.1007/s40121-015-0102-x

DOI
10.1007/s40121-015-0102-x
Journal article

Effect of CYP2B6 variants on levonorgestrel pharmacokinetics when combined with efavirenz based antiretroviral therapy.

Neary, M. G., Lamorde, M., Olagunju, A., Darin, K., Merry, C., Byakika-Kibwika, P., . . . Scarsi, K. (n.d.). Effect of CYP2B6 variants on levonorgestrel pharmacokinetics when combined with efavirenz based antiretroviral therapy.. In CROI. Boston, MA, USA.

Conference Paper

Interaction of Darunavir/Ritonavir and Darunavir/Cobicistat With Rifampicin In Vitro

Roberts, O., Back, D., Khoo, S., Owen, A., & Siccardi, M. (2016). Interaction of Darunavir/Ritonavir and Darunavir/Cobicistat With Rifampicin In Vitro. In CROI. Boston, USA.

Conference Paper

Effect of nondisclosure of HIV status in sexual health clinics on unlinked anonymous HIV prevalence estimates in England, 2005-2009

Savage, E. J., Lowndes, C. M., Sullivan, A. K., Back, D. J., Else, L. J., Murphy, G., & Gill, O. N. (2016). Effect of nondisclosure of HIV status in sexual health clinics on unlinked anonymous HIV prevalence estimates in England, 2005-2009. AIDS, 30(1), 145-149. doi:10.1097/QAD.0000000000000868

DOI
10.1097/QAD.0000000000000868
Journal article

2015

Physiologically Based Pharmacokinetic Modelling to Inform Development of Intramuscular Long-Acting Nanoformulations for HIV

Rajoli, R. K. R., Back, D. J., Rannard, S., Meyers, C. L. F., Flexner, C., Owen, A., & Siccardi, M. (2015). Physiologically Based Pharmacokinetic Modelling to Inform Development of Intramuscular Long-Acting Nanoformulations for HIV. CLINICAL PHARMACOKINETICS, 54(6), 639-650. doi:10.1007/s40262-014-0227-1

DOI
10.1007/s40262-014-0227-1
Journal article

Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, Uganda

Seden, K., Merry, C., Hewson, R., Siccardi, M., Lamorde, M., Byakika-Kibwika, P., . . . Khoo, S. H. (2015). Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, Uganda. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(12), 3317-3322. doi:10.1093/jac/dkv259

DOI
10.1093/jac/dkv259
Journal article

Reply to "Debilitating fatigue as a treatment indication in chronic hepatitis C".

Pawlotsky, J. -M., Aghemo, A., Back, D., Dusheiko, G., Forns, X., Puoti, M., . . . EASL Recommendations on Treatment of Hepatitis C 2015 panel. (2015). Reply to "Debilitating fatigue as a treatment indication in chronic hepatitis C".. Journal of hepatology, 63(6), 1535-1536. doi:10.1016/j.jhep.2015.09.004

DOI
10.1016/j.jhep.2015.09.004
Journal article

Predicting Utility of Long-Acting Injectables in Paediatric Patients With PBPK Models

Rajoli, R. K. R., Siccardi, M., Owen, A., Back, D., & Rannard, S. (2016, February 22). Predicting Utility of Long-Acting Injectables in Paediatric Patients With PBPK Models. In Conference on Retroviral and Opportunistic Infections. Boston, MA. Retrieved from http://www.croiconference.org/

Conference Paper

Interaction Between Amiodarone and Sofosbuvir-based Treatment for Hepatitis C Virus Infection: Potential Mechanisms and Lessons to be Learned

Back, D. J., & Burger, D. M. (2015). Interaction Between Amiodarone and Sofosbuvir-based Treatment for Hepatitis C Virus Infection: Potential Mechanisms and Lessons to be Learned. GASTROENTEROLOGY, 149(6), 1315-1317. doi:10.1053/j.gastro.2015.09.031

DOI
10.1053/j.gastro.2015.09.031
Journal article

Twenty years of boosting antiretroviral agents: where are we today?

Boffito, M., Back, D., & Gatell, J. M. (2015). Twenty years of boosting antiretroviral agents: where are we today?. AIDS (London, England), 29(17), 2229-2233. doi:10.1097/qad.0000000000000800

DOI
10.1097/qad.0000000000000800
Journal article

Single oral dose of maraviroc does not prevent ex-vivo HIV infection of rectal mucosa in HIV-1 negative human volunteers.

Coll, J., Moltó, J., Boix, J., Gómez-Mora, E., Else, L., García, E., . . . Cabrera, C. (2015). Single oral dose of maraviroc does not prevent ex-vivo HIV infection of rectal mucosa in HIV-1 negative human volunteers.. AIDS (London, England), 29(16), 2149-2154. doi:10.1097/qad.0000000000000769

DOI
10.1097/qad.0000000000000769
Journal article

Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation

Dickinson, L., Yapa, H. M., Jackson, A., Moyle, G., Else, L., Amara, A., . . . Boffito, M. (2015). Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59(10), 6080-6086. doi:10.1128/AAC.01441-15

DOI
10.1128/AAC.01441-15
Journal article

Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast-milk spots

Olagunju, A., Amara, A., Waitt, C., Else, L., Penchala, S. D., Bolaji, O., . . . Khoo, S. (2015). Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast-milk spots. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(10), 2816-2822. doi:10.1093/jac/dkv174

DOI
10.1093/jac/dkv174
Journal article

Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naïve HIV-Infected Patients: Results of the ENCORE1 Study.

Dickinson, L., Amin, J., Else, L., Boffito, M., Egan, D., Owen, A., . . . Puls, R. (2015). Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naïve HIV-Infected Patients: Results of the ENCORE1 Study.. Clinical pharmacology and therapeutics, 98(4), 406-416. doi:10.1002/cpt.156

DOI
10.1002/cpt.156
Journal article

Drug Interactions of Hepatitis C Direct-Acting Antivirals in the HIV-Infected Person

El-Sherif, O., & Back, D. (2015). Drug Interactions of Hepatitis C Direct-Acting Antivirals in the HIV-Infected Person. CURRENT HIV/AIDS REPORTS, 12(3), 336-343. doi:10.1007/s11904-015-0277-5

DOI
10.1007/s11904-015-0277-5
Journal article

Increasing use of 'party drugs' in people living with HIV on antiretrovirals: a concern for patient safety

Bracchi, M., Stuart, D., Castles, R., Khoo, S., Back, D., & Boffito, M. (2015). Increasing use of 'party drugs' in people living with HIV on antiretrovirals: a concern for patient safety. AIDS, 29(13), 1585-1592. doi:10.1097/QAD.0000000000000786

DOI
10.1097/QAD.0000000000000786
Journal article

Breast Milk Pharmacokinetics of Efavirenz and Breastfed Infants' Exposure in Genetically Defined Subgroups of Mother-Infant Pairs: An Observational Study

Olagunju, A., Bolaji, O., Amara, A., Waitt, C., Else, L., Adejuyigbe, E., . . . Owen, A. (2015). Breast Milk Pharmacokinetics of Efavirenz and Breastfed Infants' Exposure in Genetically Defined Subgroups of Mother-Infant Pairs: An Observational Study. Clin Infect Dis, 61(3), 453-463. doi:10.1093/cid/civ317

DOI
10.1093/cid/civ317
Journal article

EASL Recommendations on Treatment of Hepatitis C 2015.

European Association for Study of Liver. (2015). EASL Recommendations on Treatment of Hepatitis C 2015.. Journal of hepatology, 63(1), 199-236. doi:10.1016/j.jhep.2015.03.025

DOI
10.1016/j.jhep.2015.03.025
Journal article

Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naive HIV-Infected Patients: Results of the ENCORE1 Study

Dickinson, L., Amin, J., Else, L., Boffito, M., Egan, D., Owen, A., . . . R Puls, O. B. O. T. E. S. G. (2015). Pharmacokinetic and Pharmacodynamic Comparison of Once-Daily Efavirenz (400 mg vs. 600 mg) in Treatment-Naive HIV-Infected Patients: Results of the ENCORE1 Study. Clin Pharmacol Ther, 98(4), 406-416.

Journal article

A Phase I study to assess the safety, tolerability and pharmacokinetic profile of boceprevir and sildenafil when dosed separately and together, in healthy male volunteers

Mora-Peris, B., Else, L., Goldmeier, D., Mears, A., Weston, R., Cooke, G., . . . Winston, A. (2015). A Phase I study to assess the safety, tolerability and pharmacokinetic profile of boceprevir and sildenafil when dosed separately and together, in healthy male volunteers. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(6), 1812-1815. doi:10.1093/jac/dkv035

DOI
10.1093/jac/dkv035
Journal article

Antiviral activity and CSF concentrations of 600/100 mg of darunavir/ritonavir once daily in HIV-1 patients with plasma viral suppression.

Di Yacovo, M. S., Moltó, J., Ferrer, E., Curran, A., Else, L., Gisslén, M., . . . Podzamczer, D. (2015). Antiviral activity and CSF concentrations of 600/100 mg of darunavir/ritonavir once daily in HIV-1 patients with plasma viral suppression.. The Journal of antimicrobial chemotherapy, 70(5), 1513-1516. doi:10.1093/jac/dku558

DOI
10.1093/jac/dku558
Journal article

Pharmacogenetics of Pregnancy-Induced Changes in Efavirenz Pharmacokinetics

Olagunju, A., Bolaji, O., Amara, A., Else, L., Okafor, O., Adejuyigbe, E., . . . Owen, A. (2015). Pharmacogenetics of Pregnancy-Induced Changes in Efavirenz Pharmacokinetics. CLINICAL PHARMACOLOGY & THERAPEUTICS, 97(3), 298-306. doi:10.1002/cpt.43

DOI
10.1002/cpt.43
Journal article

Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS

Olagunju, A., Bolaji, O. O., Amara, A., Waitt, C., Else, L., Soyinka, J., . . . Khoo, S. (2015). Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(2), 555-561. doi:10.1093/jac/dku420

DOI
10.1093/jac/dku420
Journal article

Effect of intermittent rifampicin on the pharmacokinetics and safety of raltegravir

Reynolds, H. E., Chrdle, A., Egan, D., Chaponda, M., Else, L., Chiong, J., . . . Khoo, S. H. (2015). Effect of intermittent rifampicin on the pharmacokinetics and safety of raltegravir. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(2), 550-554. doi:10.1093/jac/dku376

DOI
10.1093/jac/dku376
Journal article

The pharmacokinetic profile of raltegravircontaining antiretroviral therapy in HIV-infected individuals over 60 years of age

Vera, J. H., Jackson, A., Dickinson, L., Else, L., Barber, T., Mora-Peris, B., . . . Winston, A. (2015). The pharmacokinetic profile of raltegravircontaining antiretroviral therapy in HIV-infected individuals over 60 years of age. HIV CLINICAL TRIALS, 16(1), 39-42. doi:10.1179/1528433614Z.0000000006

DOI
10.1179/1528433614Z.0000000006
Journal article

The pharmacokinetic profile of raltegravir-containing antiretroviral therapy in HIV-infected individuals over 60 years of age.

Vera, J. H., Jackson, A., Dickinson, L., Else, L., Barber, T., Mora-Peris, B., . . . Winston, A. (2015). The pharmacokinetic profile of raltegravir-containing antiretroviral therapy in HIV-infected individuals over 60 years of age.. HIV clinical trials, 16(1), 39-42.

Journal article

Steady-state pharmacokinetics of rilpivirine under different meal conditions in HIV-1-infected Ugandan adults

Lamorde, M., Walimbwa, S., Byakika-Kibwika, P., Katwere, M., Mukisa, L., Sempa, J. B., . . . Merry, C. (2015). Steady-state pharmacokinetics of rilpivirine under different meal conditions in HIV-1-infected Ugandan adults. J Antimicrob Chemother, 70(5), 1482-1486.

Journal article

Switching safely: pharmacokinetics, efficacy and safety of switching efavirenz to maraviroc twice daily in patients on suppressive antiretroviral therapy.

Waters, L., Jackson, A., Else, L., Rockwood, N., Newell, S., Back, D., . . . Boffito, M. (2015). Switching safely: pharmacokinetics, efficacy and safety of switching efavirenz to maraviroc twice daily in patients on suppressive antiretroviral therapy.. Antiviral therapy, 20(2), 157-163. doi:10.3851/imp2817

DOI
10.3851/imp2817
Journal article

Use of In Vitro to In Vivo Extrapolation to Predict the Optimal Strategy for Patients Switching from Efavirenz to Maraviroc or Nevirapine

Schipani, A., Back, D., Owen, A., Davies, G., Khoo, S., & Siccardi, M. (2015). Use of In Vitro to In Vivo Extrapolation to Predict the Optimal Strategy for Patients Switching from Efavirenz to Maraviroc or Nevirapine. CLINICAL PHARMACOKINETICS, 54(1), 107-116. doi:10.1007/s40262-014-0184-8

DOI
10.1007/s40262-014-0184-8
Journal article

2014

Antiretroviral drugs for prevention of mother-to-child transmission: pharmacologic considerations for a public health approach

Lamorde, M., Schapiro, J. M., Burger, D., & Back, D. J. (2014). Antiretroviral drugs for prevention of mother-to-child transmission: pharmacologic considerations for a public health approach. AIDS, 28(17), 2551-2563. doi:10.1097/QAD.0000000000000439

DOI
10.1097/QAD.0000000000000439
Journal article

Efavirenz- but not nevirapine-based antiretroviral therapy decreases exposure to the levonorgestrel released from a sub-dermal contraceptive implant

Scarsi, K., Lamorde, M., Darin, K., Dilly Penchala, S., Else, L., Nakalema, S., . . . Back, D. (2014). Efavirenz- but not nevirapine-based antiretroviral therapy decreases exposure to the levonorgestrel released from a sub-dermal contraceptive implant. J Int AIDS Soc, 17(4 Supp), 19484.

Journal article

Simulation of the impact of rifampicin on darunavir/ritonavir PK and dose adjustment strategies in HIV‐infected patients: a population PK approach

Dickinson, L., Winston, A., Boffito, M., Khoo, S., Back, D., & Siccardi, M. (2014). Simulation of the impact of rifampicin on darunavir/ritonavir PK and dose adjustment strategies in HIV‐infected patients: a population PK approach. Journal of the International AIDS Society, 17(4S3). doi:10.7448/ias.17.4.19586

DOI
10.7448/ias.17.4.19586
Journal article

Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy

Else, L. J., Jackson, V., Brennan, M., Back, D. J., Khoo, S. H., Coulter-Smith, S., & Lambert, J. S. (2014). Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy. HIV MEDICINE, 15(10), 604-610. doi:10.1111/hiv.12164

DOI
10.1111/hiv.12164
Journal article

No pharmacokinetic interaction between raltegravir and amlodipine: importance for co-prescribing in ageing HIV-infected individuals

Singh, G. J., Jackson, A., D'Avolio, A., Else, L., De Nicolo, A., Bonora, S., . . . Boffito, M. (2014). No pharmacokinetic interaction between raltegravir and amlodipine: importance for co-prescribing in ageing HIV-infected individuals. AIDS, 28(13), 1993-1995. doi:10.1097/QAD.0000000000000356

DOI
10.1097/QAD.0000000000000356
Journal article

Pharmacokinetics of the co-administration of boceprevir and St John's wort to male and female healthy volunteers.

Jackson, A., D'Avolio, A., Moyle, G., Bonora, S., Di Perri, G., Else, L., . . . Boffito, M. (2014). Pharmacokinetics of the co-administration of boceprevir and St John's wort to male and female healthy volunteers.. The Journal of antimicrobial chemotherapy, 69(7), 1911-1915. doi:10.1093/jac/dku060

DOI
10.1093/jac/dku060
Journal article

Rilpivirine exposure in plasma and sanctuary site compartments after switching from nevirapine-containing combined antiretroviral therapy

Mora-Peris, B., Watson, V., Vera, J. H., Weston, R., Waldman, A. D., Kaye, S., . . . Winston, A. (2014). Rilpivirine exposure in plasma and sanctuary site compartments after switching from nevirapine-containing combined antiretroviral therapy. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 69(6), 1642-1647. doi:10.1093/jac/dku018

DOI
10.1093/jac/dku018
Journal article

Abacavir forms novel cross-linking abacavir protein adducts in patients

Meng, X., Lawrenson, A. S., Berry, N. G., Maggs, J. L., French, N. S., Back, D. J., . . . Park, B. K. (2014). Abacavir forms novel cross-linking abacavir protein adducts in patients. Chemical Research in Toxicology, 27(04), 524-535. doi:10.1021/tx400406p

DOI
10.1021/tx400406p
Journal article

<i>CYP3A4</i>*22 (c.522-191 C&gt;T; rs35599367) is associated with lopinavir pharmacokinetics in HIV-positive adults

Olagunju, A., Schipani, A., Siccardi, M., Egan, D., Khoo, S., Back, D., & Owen, A. (2014). <i>CYP3A4</i>*22 (c.522-191 C&gt;T; rs35599367) is associated with lopinavir pharmacokinetics in HIV-positive adults. PHARMACOGENETICS AND GENOMICS, 24(9), 459-463. doi:10.1097/FPC.0000000000000073

DOI
10.1097/FPC.0000000000000073
Journal article

A Compartmental Pharmacokinetic Evaluation of Long-Acting Rilpivirine in HIV-Negative Volunteers for Pre-Exposure Prophylaxis

Jackson, A. G. A., Else, L. J., Mesquita, P. M. M., Egan, D., Back, D. J., Karolia, Z., . . . Boffito, M. (2014). A Compartmental Pharmacokinetic Evaluation of Long-Acting Rilpivirine in HIV-Negative Volunteers for Pre-Exposure Prophylaxis. CLINICAL PHARMACOLOGY & THERAPEUTICS, 96(3), 314-323. doi:10.1038/clpt.2014.118

DOI
10.1038/clpt.2014.118
Journal article

Quantification of rilpivirine in human plasma, cervicovaginal fluid, rectal fluid and genital/rectal mucosal tissues using liquid chromatography-tandem mass spectrometry

Else, L. J., Tjia, J., Jackson, A., Penchala, S. D., Egan, D., Boffito, M., . . . Back, D. J. (2014). Quantification of rilpivirine in human plasma, cervicovaginal fluid, rectal fluid and genital/rectal mucosal tissues using liquid chromatography-tandem mass spectrometry. BIOANALYSIS, 6(14), 1907-1921. doi:10.4155/BIO.14.59

DOI
10.4155/BIO.14.59
Journal article

Should the dose of tenofovir be reduced to 200-250 mg/day, when combined with protease inhibitors?

Hill, A., Khoo, S., Back, D., Pozniak, A., & Boffito, M. (2014). Should the dose of tenofovir be reduced to 200-250 mg/day, when combined with protease inhibitors?. J Int AIDS Soc, 17(4 Supp), 19583.

Journal article

Simulation of the impact of rifampicin on darunavir/ritonavir PK and dose adjustment strategies in HIV-infected patients: a population PK approach

Dickinson, L., Winston, A., Boffito, M., Khoo, S., Back, D., & Siccardi, M. (2014). Simulation of the impact of rifampicin on darunavir/ritonavir PK and dose adjustment strategies in HIV-infected patients: a population PK approach. J Int AIDS Soc, 17(4 Supp), 19586.

Journal article

2013

Induction of Influx and Efflux Transporters and Cytochrome P450 3A4 in Primary Human Hepatocytes by Rifampin, Rifabutin, and Rifapentine

Williamson, B., Dooley, K. E., Zhang, Y., Back, D. J., & Owen, A. (2013). Induction of Influx and Efflux Transporters and Cytochrome P450 3A4 in Primary Human Hepatocytes by Rifampin, Rifabutin, and Rifapentine. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 57(12), 6366-6369. doi:10.1128/AAC.01124-13

DOI
10.1128/AAC.01124-13
Journal article

Drug-drug interactions in HIV therapy: is it all clear?

Burger, D., & Back, D. (2013). Drug-drug interactions in HIV therapy: is it all clear?. Antiviral therapy, 18(5), 649-650. doi:10.3851/imp2688

DOI
10.3851/imp2688
Journal article

Interactions between tenofovir and nevirapine in CD4+T cells and monocyte-derived macrophages restrict their intracellular accumulation

Liptrott, N. J., Curley, P., Moss, D., Back, D. J., Khoo, S. H., & Owen, A. (2013). Interactions between tenofovir and nevirapine in CD4+T cells and monocyte-derived macrophages restrict their intracellular accumulation. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 68(11), 2545-2549. doi:10.1093/jac/dkt225

DOI
10.1093/jac/dkt225
Journal article

Rilpivirine Inhibits Drug Transporters ABCB1, SLC22A1, and SLC22A2 <i>In Vitro</i>

Moss, D. M., Liptrott, N. J., Curley, P., Siccardi, M., Back, D. J., & Owen, A. (2013). Rilpivirine Inhibits Drug Transporters ABCB1, SLC22A1, and SLC22A2 <i>In Vitro</i>. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 57(11), 5612-5618. doi:10.1128/AAC.01421-13

DOI
10.1128/AAC.01421-13
Journal article

The importance of drug-drug interactions in the DAA era.

Back, D., & Else, L. (2013). The importance of drug-drug interactions in the DAA era.. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 45 Suppl 5, S343-S348. doi:10.1016/j.dld.2013.07.008

DOI
10.1016/j.dld.2013.07.008
Journal article

Validation of an electrospray ionisation LC-MS/MS method for quantitative analysis of telaprevir and its R-diastereomer

Penchala, S. D., Tjia, J., El Sherif, O., Back, D. J., Khoo, S. H., & Else, L. J. (2013). Validation of an electrospray ionisation LC-MS/MS method for quantitative analysis of telaprevir and its R-diastereomer. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 932, 100-110. doi:10.1016/j.jchromb.2013.06.013

DOI
10.1016/j.jchromb.2013.06.013
Journal article

Virological efficacy in cerebrospinal fluid and neurocognitive status in patients with long-term monotherapy based on lopinavir/ritonavir: an exploratory study.

Santos, J. R., Muñoz-Moreno, J. A., Moltó, J., Prats, A., Curran, A., Domingo, P., . . . Clotet, B. (2013). Virological efficacy in cerebrospinal fluid and neurocognitive status in patients with long-term monotherapy based on lopinavir/ritonavir: an exploratory study.. PloS one, 8(7), e70201. doi:10.1371/journal.pone.0070201

DOI
10.1371/journal.pone.0070201
Journal article

Predicting intestinal absorption of raltegravir using a population-based ADME simulation

Moss, D. M., Siccardi, M., Back, D. J., & Owen, A. (2013). Predicting intestinal absorption of raltegravir using a population-based ADME simulation. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 68(7), 1627-1634. doi:10.1093/jac/dkt084

DOI
10.1093/jac/dkt084
Journal article

Prediction of drug-drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach

Siccardi, M., Marzolini, C., Seden, K., Almond, L., Kirov, A., Khoo, S., . . . Back, D. (2013). Prediction of drug-drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach. CLINICAL PHARMACOKINETICS, 52(7), 583-592. doi:10.1007/s40262-013-0056-7

DOI
10.1007/s40262-013-0056-7
Journal article

Effects of age on antiretroviral plasma drug concentration in HIV-infected subjects undergoing routine therapeutic drug monitoring.

Winston, A., Jose, S., Gibbons, S., Back, D., Stohr, W., Post, F., . . . UK Collaborative HIV Cohort Study. (2013). Effects of age on antiretroviral plasma drug concentration in HIV-infected subjects undergoing routine therapeutic drug monitoring.. The Journal of antimicrobial chemotherapy, 68(6), 1354-1359. doi:10.1093/jac/dkt029

DOI
10.1093/jac/dkt029
Journal article

Pharmacokinetic profile and safety of 150 mg of maraviroc dosed with 800/100 mg of darunavir/ritonavir all once daily, with and without nucleoside analogues, in HIV-infected subjects.

Mora-Peris, B., Croucher, A., Else, L. J., Vera, J. H., Khoo, S., Scullard, G., . . . Winston, A. (2013). Pharmacokinetic profile and safety of 150 mg of maraviroc dosed with 800/100 mg of darunavir/ritonavir all once daily, with and without nucleoside analogues, in HIV-infected subjects.. The Journal of antimicrobial chemotherapy, 68(6), 1348-1353. doi:10.1093/jac/dkt006

DOI
10.1093/jac/dkt006
Journal article

Detection of Drug Bioactivation in Vivo: Mechanism of Nevirapine-Albumin Conjugate Formation in Patients

Meng, X., Howarth, A., Earnshaw, C. J., Jenkins, R. E., French, N. S., Back, D. J., . . . Park, B. K. (2013). Detection of Drug Bioactivation in Vivo: Mechanism of Nevirapine-Albumin Conjugate Formation in Patients. CHEMICAL RESEARCH IN TOXICOLOGY, 26(4), 575-583. doi:10.1021/tx4000107

DOI
10.1021/tx4000107
Journal article

Clinical management of drug-drug interactions in HCV therapy: challenges and solutions.

Burger, D., Back, D., Buggisch, P., Buti, M., Craxí, A., Foster, G., . . . Zeuzem, S. (2013). Clinical management of drug-drug interactions in HCV therapy: challenges and solutions.. Journal of hepatology, 58(4), 792-800. doi:10.1016/j.jhep.2012.10.027

DOI
10.1016/j.jhep.2012.10.027
Journal article

Rilpivirine concentrations in seminal plasma in HIV infected patients

Watson, V., Mora-Peris, B., Tjia, J., Vera, J. H., Weston, R., Khoo, S., . . . Winston, A. (2013). Rilpivirine concentrations in seminal plasma in HIV infected patients. Poster session presented at the meeting of 14th International Workshop on Clinical Pharmacology of HIV Therapy. Netherlands.

Poster

Lower artemether, dihydroartemisinin and lumefantrine concentrations during rifampicin-based tuberculosis treatment

Lamorde, M., Byakika-Kibwika, P., Mayito, J., Nabukeera, L., Ryan, M., Hanpithakpong, W., . . . Merry, C. (2013). Lower artemether, dihydroartemisinin and lumefantrine concentrations during rifampicin-based tuberculosis treatment. AIDS, 27(6), 961-965. doi:10.1097/QAD.0b013e32835cae3b

DOI
10.1097/QAD.0b013e32835cae3b
Journal article

Drug-drug interactions between antiretrovirals and drugs used in the management of neglected tropical diseases: important considerations in the WHO 2020 Roadmap and London Declaration on Neglected Tropical Diseases.

Seden, K., Khoo, S., Back, D., Prevatt, N., Lamorde, M., Byakika-Kibwika, P., . . . Merry, C. (2013). Drug-drug interactions between antiretrovirals and drugs used in the management of neglected tropical diseases: important considerations in the WHO 2020 Roadmap and London Declaration on Neglected Tropical Diseases.. AIDS (London, England), 27(5), 675-686. doi:10.1097/qad.0b013e32835ca9b4

DOI
10.1097/qad.0b013e32835ca9b4
Journal article

Non-disclosure of HIV status in UK sexual health clinics-a pilot study to identify non-disclosure within a national unlinked anonymous seroprevalence survey

Sullivan, A. K., Savage, E. J., Lowndes, C. M., Paul, G., Murphy, G., Carne, S., . . . Gill, O. N. (2013). Non-disclosure of HIV status in UK sexual health clinics-a pilot study to identify non-disclosure within a national unlinked anonymous seroprevalence survey. SEXUALLY TRANSMITTED INFECTIONS, 89(2), 120-121. doi:10.1136/sextrans-2012-050801

DOI
10.1136/sextrans-2012-050801
Journal article

Tenofovir, Emtricitabine Intracellular and Plasma, and Efavirenz Plasma Concentration Decay Following Drug Intake Cessation: Implications for HIV Treatment and Prevention

Jackson, A., Moyle, G., Watson, V., Tjia, J., Ammara, A., Back, D., . . . Boffito, M. (2013). Tenofovir, Emtricitabine Intracellular and Plasma, and Efavirenz Plasma Concentration Decay Following Drug Intake Cessation: Implications for HIV Treatment and Prevention. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 62(3), 275-281. doi:10.1097/QAI.0b013e3182829bd0

DOI
10.1097/QAI.0b013e3182829bd0
Journal article

Tenofovir, emtricitabine intracellular and plasma, and efavirenz plasma concentration decay following drug intake cessation: implications for HIV treatment and prevention

Jackson, A., Moyle, G., Watson, V., Tjia, J., Amara, A., Back, D., . . . Boffito, M. (2013). Tenofovir, emtricitabine intracellular and plasma, and efavirenz plasma concentration decay following drug intake cessation: implications for HIV treatment and prevention. JAIDS: Journal of Acquired Immune Deficiency Syndromes, 62(3), 275-281. doi:10.1097/QAI.0b013e3182829bd0

DOI
10.1097/QAI.0b013e3182829bd0
Journal article

Global patient safety and antiretroviral drug-drug interactions in the resource-limited setting.

Seden, K., Khoo, S. H., Back, D., Byakika-Kibwika, P., Lamorde, M., Ryan, M., & Merry, C. (2013). Global patient safety and antiretroviral drug-drug interactions in the resource-limited setting.. The Journal of antimicrobial chemotherapy, 68(1), 1-3. doi:10.1093/jac/dks346

DOI
10.1093/jac/dks346
Journal article

Prediction of Etravirine Pharmacogenetics using a Physiologically Based Pharmacokinetic approach

Siccardi, M., Olagunju, A., Curley, P., Hobson, J., Khoo, S., Back, D., & Owen, A. (2013). Prediction of Etravirine Pharmacogenetics using a Physiologically Based Pharmacokinetic approach. In 20th Conference on Retroviruses and Opportunistic Infections. Atlanta, USA.

Conference Paper

Simultaneous Population Pharmacokinetic Modelling of Atazanavir and Ritonavir in HIV-Infected Adults and Assessment of Different Dose Reduction Strategies

Schipani, A., Dickinson, L., Boffito, M., Austin, R., Owen, A., Back, D., . . . Davies, G. (2013). Simultaneous Population Pharmacokinetic Modelling of Atazanavir and Ritonavir in HIV-Infected Adults and Assessment of Different Dose Reduction Strategies. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 62(1), 60-66. doi:10.1097/QAI.0b013e3182737231

DOI
10.1097/QAI.0b013e3182737231
Journal article

Utilising In Vitro-In Vivo extrapolation to investigate efavirenz penetration into the central nervous system

Curley, P., Martin, P., Liptrott, N., Back, D., Owen, A., & Siccardi, M. (2013). Utilising In Vitro-In Vivo extrapolation to investigate efavirenz penetration into the central nervous system. Poster session presented at the meeting of 14th International Workshop on Clinical Pharmacology of HIV Therapy. Netherlands.

Poster

2012

Efavirenz in an obese HIV-infected patient - a report and an <i>in vitro</i>-<i>in vivo</i> extrapolation model indicate risk of underdosing

de Roche, M., Siccardi, M., Stoeckle, M., Livio, F., Back, D., Battegay, M., & Marzolini, C. (2012). Efavirenz in an obese HIV-infected patient - a report and an <i>in vitro</i>-<i>in vivo</i> extrapolation model indicate risk of underdosing. ANTIVIRAL THERAPY, 17(7), 1381-1384. doi:10.3851/IMP2107

DOI
10.3851/IMP2107
Journal article

Development and validation of a LC‐MS/MS assay to quantify intracellular tenofovir‐diphosphate (TFV‐DP) and emtricitabine‐triphosphate (FTC‐TP)

Watson, V., Else, L., Tjia, J., Khoo, S., & Back, D. (2012). Development and validation of a LC‐MS/MS assay to quantify intracellular tenofovir‐diphosphate (TFV‐DP) and emtricitabine‐triphosphate (FTC‐TP). Journal of the International AIDS Society, 15(S4), 1. doi:10.7448/ias.15.6.18336

DOI
10.7448/ias.15.6.18336
Journal article

Anti-retroviral drugs do not facilitate hepatitis C virus (HCV) infection in vitro.

Sandmann, L., Wilson, M., Back, D., Wedemeyer, H., Manns, M. P., Steinmann, E., . . . Ciesek, S. (2012). Anti-retroviral drugs do not facilitate hepatitis C virus (HCV) infection in vitro.. Antiviral research, 96(1), 51-58. doi:10.1016/j.antiviral.2012.07.005

DOI
10.1016/j.antiviral.2012.07.005
Journal article

Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an <i>In Vitro</i>-<i>In Vivo</i> Extrapolation Model

Siccardi, M., Almond, L., Schipani, A., Csajka, C., Marzolini, C., Wyen, C., . . . Back, D. (2012). Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an <i>In Vitro</i>-<i>In Vivo</i> Extrapolation Model. CLINICAL PHARMACOLOGY & THERAPEUTICS, 92(4), 494-502. doi:10.1038/clpt.2012.61

DOI
10.1038/clpt.2012.61
Journal article

Estimation of the effect of <i>SLCO1B1</i> polymorphisms on lopinavir plasma concentration in HIV-infected adults

Schipani, A., Egan, D., Dickinson, L., Davies, G., Boffito, M., Youle, M., . . . Owen, A. (2012). Estimation of the effect of <i>SLCO1B1</i> polymorphisms on lopinavir plasma concentration in HIV-infected adults. ANTIVIRAL THERAPY, 17(5), 861-868. doi:10.3851/IMP2095

DOI
10.3851/IMP2095
Journal article

Efavirenz pharmacokinetics in cerebrospinal fluid and plasma over a 24-hour dosing interval

Yilmaz, A., Watson, V., Dickinson, L., & Back, D. (2012). Efavirenz pharmacokinetics in cerebrospinal fluid and plasma over a 24-hour dosing interval. Antimicrobial Agents and Chemotherapy, 56(9), 4583-4585.

Journal article

Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults.

Byakika-Kibwika, P., Lamorde, M., Mayito, J., Nabukeera, L., Namakula, R., Mayanja-Kizza, H., . . . Merry, C. (2012). Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults.. The Journal of antimicrobial chemotherapy, 67(9), 2213-2221. doi:10.1093/jac/dks207

DOI
10.1093/jac/dks207
Journal article

Steady-state pharmacokinetics of lopinavir plus ritonavir when administered under different meal conditions in HIV-infected Ugandan adults.

Lamorde, M., Byakika-Kibwika, P., Boffito, M., Nabukeera, L., Mayito, J., Ogwal-Okeng, J., . . . Merry, C. (2012). Steady-state pharmacokinetics of lopinavir plus ritonavir when administered under different meal conditions in HIV-infected Ugandan adults.. Journal of acquired immune deficiency syndromes (1999), 60(3), 295-298. doi:10.1097/qai.0b013e3182567a35

DOI
10.1097/qai.0b013e3182567a35
Journal article

Divalent Metals and pH Alter Raltegravir Disposition <i>In Vitro</i>

Moss, D. M., Siccardi, M., Murphy, M., Piperakis, M. M., Khoo, S. H., Back, D. J., & Owen, A. (2012). Divalent Metals and pH Alter Raltegravir Disposition <i>In Vitro</i>. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56(6), 3020-3026. doi:10.1128/AAC.06407-11

DOI
10.1128/AAC.06407-11
Journal article

Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults.

Byakika-Kibwika, P., Lamorde, M., Okaba-Kayom, V., Mayanja-Kizza, H., Katabira, E., Hanpithakpong, W., . . . Merry, C. (2012). Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults.. The Journal of antimicrobial chemotherapy, 67(5), 1217-1223. doi:10.1093/jac/dkr596

DOI
10.1093/jac/dkr596
Journal article

Development and validation of a LC-MS/MS assay to quantify 10 anti-retroviral (ARV) drugs in cerebral spinal fluid (CSF)

Watson, V., Tjia, J., Szwandt, S., Else, L., Khoo, S., & Back, D. (2012). Development and validation of a LC-MS/MS assay to quantify 10 anti-retroviral (ARV) drugs in cerebral spinal fluid (CSF). Poster session presented at the meeting of 13th International Workshop on Clinical Pharmacology of HIV Therapy. Barcelona, Spain.

Poster

Intrapatient and Interpatient Pharmacokinetic Variability of Raltegravir in the Clinical Setting

Siccardi, M., D'Avolio, A., Rodriguez-Novoa, S., Cuenca, L., Simiele, M., Baietto, L., . . . Di Perri, G. (2012). Intrapatient and Interpatient Pharmacokinetic Variability of Raltegravir in the Clinical Setting. THERAPEUTIC DRUG MONITORING, 34(2), 232-235. doi:10.1097/FTD.0b013e31824aa50a

DOI
10.1097/FTD.0b013e31824aa50a
Journal article

Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies

Taylor, S., Jayasuriya, A., Fisher, M., Allan, S., Wilkins, E., Gilleran, G., . . . Smit, E. (2012). Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies. Journal of Antimicrobial Chemotherapy, 67(3), 675-680. doi:10.1093/jac/dkr491

DOI
10.1093/jac/dkr491
Journal article

Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies

Taylor, S., Jayasuriya, A., Fisher, M., Allan, S., Wilkins, E., Gilleran, G., . . . Smit, E. (2012). Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 67(3), 675-680. doi:10.1093/jac/dkr491

DOI
10.1093/jac/dkr491
Journal article

Pharmacokinetics of Lamivudine and Lamivudine-Triphosphate after Administration of 300 Milligrams and 150 Milligrams Once Daily to Healthy Volunteers: Results of the ENCORE 2 Study

Else, L. J., Jackson, A., Puls, R., Hill, A., Fahey, P., Lin, E., . . . Boffito, M. (2012). Pharmacokinetics of Lamivudine and Lamivudine-Triphosphate after Administration of 300 Milligrams and 150 Milligrams Once Daily to Healthy Volunteers: Results of the ENCORE 2 Study. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56(3), 1427-1433. doi:10.1128/AAC.05599-11

DOI
10.1128/AAC.05599-11
Journal article

Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study

Else, L., Jackson, A., Puls, R., Hill, A., Fahey, P., Lin, E., . . . Boffito, M. (2012). Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study. Antimicrobial Agents and Chemotherapy, 56(3), 1427-1433.

Journal article

Improved Oral Bioavailability of Lopinavir in Melt-Extruded Tablet Formulation Reduces Impact of Third Trimester on Lopinavir Plasma Concentrations

Else, L. J., Douglas, M., Dickinson, L., Back, D. J., Khoo, S. H., & Taylor, G. P. (2012). Improved Oral Bioavailability of Lopinavir in Melt-Extruded Tablet Formulation Reduces Impact of Third Trimester on Lopinavir Plasma Concentrations. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56(2), 816-824. doi:10.1128/AAC.05186-11

DOI
10.1128/AAC.05186-11
Journal article

Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations.

Else, L., Douglas, M., Dickinson, L., Back, D., Khoo, S., & Taylor, G. P. (2012). Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations.. Antimicrobial agents and chemotherapy, 56(2), 816-824.

Journal article

Pharmacokinetics of abacavir and its anabolite carbovir triphosphate without and with darunavir/ritonavir or raltegravir in HIV-infected subjects.

Jackson, A., Moyle, G., Dickinson, L., Back, D., Khoo, S., Taylor, J., . . . Boffito, M. (2012). Pharmacokinetics of abacavir and its anabolite carbovir triphosphate without and with darunavir/ritonavir or raltegravir in HIV-infected subjects.. Antiviral therapy, 17(1), 19-24. doi:10.3851/imp1910

DOI
10.3851/imp1910
Journal article

Alterations in cerebrospinal fluid chemokines are associated with maraviroc exposure and in vivo metabolites measurable by magnetic resonance spectroscopy.

Vera, J. H., Garvey, L. J., Allsop, J. M., Kaye, S., McClure, M. O., Back, D., . . . Winston, A. (2012). Alterations in cerebrospinal fluid chemokines are associated with maraviroc exposure and in vivo metabolites measurable by magnetic resonance spectroscopy.. HIV clinical trials, 13(4), 222-227. doi:10.1310/hct1304-222

DOI
10.1310/hct1304-222
Journal article

Association of <i>ABCC10</i> polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS

Liptrott, N. J., Pushpakom, S., Wyen, C., Faetkenheuer, G., Hoffmann, C., Mauss, S., . . . Owen, A. (2012). Association of <i>ABCC10</i> polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS. PHARMACOGENETICS AND GENOMICS, 22(1), 10-19. doi:10.1097/FPC.0b013e32834dd82e

DOI
10.1097/FPC.0b013e32834dd82e
Journal article

Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS

Liptrott, N. J., Pushpakom, S., Wyen, C., Fätkenheuer, G., Hoffmann, C., Mauss, S., . . . Owen, A. (2012). Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS. Pharmacogenetics and Genomics, 22(1), 10-19. doi:10.1097/fpc.0b013e32834dd82e

DOI
10.1097/fpc.0b013e32834dd82e
Journal article

CNS effects of a CCR5 inhibitor in HIV-infected subjects: a pharmacokinetic and cerebral metabolite study.

Garvey, L., Nelson, M., Latch, N., Erlwein, O. W., Allsop, J. M., Mitchell, A., . . . Winston, A. (2012). CNS effects of a CCR5 inhibitor in HIV-infected subjects: a pharmacokinetic and cerebral metabolite study.. The Journal of antimicrobial chemotherapy, 67(1), 206-212. doi:10.1093/jac/dkr427

DOI
10.1093/jac/dkr427
Journal article

Divalent metals and pH alter raltegravir disposition in vitro.

Moss, D. M., Siccardi, M., Murphy, M., Piperakis, M. M., Khoo, S. H., Back, D. J., & Owen, A. (2012). Divalent metals and pH alter raltegravir disposition in vitro.. Antimicrobial Agents and Chemotherapy.

Journal article

Efavirenz pharmacokinetics in cerebrospinal fluid and plasma over a 24-hour dosing interval.

Yilmaz, A., Watson, V., Dickinson, L., & Back, D. (2012). Efavirenz pharmacokinetics in cerebrospinal fluid and plasma over a 24-hour dosing interval.. Antimicrobial Agents and Chemotherapy, 56, 4583-4585.

Journal article

Effect of Food on the Steady-State Pharmacokinetics of Tenofovir and Emtricitabine plus Efavirenz in Ugandan Adults

Lamorde, M., Byakika-Kibwika, P., Tamale, W. S., Kiweewa, F., Ryan, M., Amara, A., . . . Merry, C. (2012). Effect of Food on the Steady-State Pharmacokinetics of Tenofovir and Emtricitabine plus Efavirenz in Ugandan Adults. AIDS Research and Treatment, 2012, 1-6. doi:10.1155/2012/105980

DOI
10.1155/2012/105980
Journal article

Estimation of the effect of SLCO1B1 polymorphisms on lopinavir plasma concentration in HIV-infected adults

Schipani, A., Egan, D., Dickinson, L., Davies, G., Boffito, M., Youle, M., . . . Owen, A. (2012). Estimation of the effect of SLCO1B1 polymorphisms on lopinavir plasma concentration in HIV-infected adults. Antiviral Therapy, 17(5), 861-868.

Journal article

Global patient safety and antiretroviral drug-drug interactions in the resource-limited setting

Seden, K., Khoo, S. H., Back, D., Byakika-Kibwika, P., Lamorde, M., Ryan, M., & Merry, C. (2012). Global patient safety and antiretroviral drug-drug interactions in the resource-limited setting. Journal of Antimicrobial Chemotherapy.

Journal article

Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations.

Else, L. J., Douglas, M., Dickinson, L., Back, D. J., Khoo, S. H., & Taylor, G. P. (2012). Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations.. Antimicrobial Agents and Chemotherapy, 56, 816-824.

Journal article

Pharmacokinetics of Abacavir and its Anabolite Carbovir Triphosphate without and with Darunavir/ Ritonavir or Raltegravir in HIV-Infected Subjects

Jackson, A., Moyle, G., Dickinson, L., Back, D., Khoo, S., Taylor, J., . . . Boffito, M. (2012). Pharmacokinetics of Abacavir and its Anabolite Carbovir Triphosphate without and with Darunavir/ Ritonavir or Raltegravir in HIV-Infected Subjects. Antiviral Therapy, 17(1), 19-24. doi:10.3851/imp1910

DOI
10.3851/imp1910
Journal article

Pharmacokinetics of abacavir and its anabolite carbovir triphosphate without and with darunavir/ritonavir or raltegravir in HIV-infected subjects.

Jackson, A., Moyle, G., Dickinson, L., Back, D., Khoo, S., Taylor, J., . . . Boffito, M. (2012). Pharmacokinetics of abacavir and its anabolite carbovir triphosphate without and with darunavir/ritonavir or raltegravir in HIV-infected subjects.. Antiviral Therapy., 17, 19-24.

Journal article

Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study

Else, L., Jackson, A., Puls, R., Hill, A., Fahey, P., Lin, E., . . . Boffito, M. (2012). Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study. Antimicrob Agents Chemother, 56(3), 1427-1433.

Journal article

Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study.

Else, L. J., Jackson, A., Puls, R., Hill, A., Fahey, P., Lin, E., . . . Boffito, M. (2012). Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study.. Antimicrobial Agents and Chemotherapy, 56, 1427-1433.

Journal article

Simultaneous population pharmacokinetic modelling of atazanavir and ritonavir in HIV-infected adults and assessment of different dose reduction strategies

Schipani, A., Dickinson, L., Boffito, M., Austin, R., Owen, A., Back, D., . . . Davies, G. (2012). Simultaneous population pharmacokinetic modelling of atazanavir and ritonavir in HIV-infected adults and assessment of different dose reduction strategies. Journal of Acquired Immune Deficiency Syndrome.

Journal article

2011

Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid)

Else, L. J., Taylor, S., Back, D. J., & Khoo, S. H. (2011). Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid). ANTIVIRAL THERAPY, 16(8), 1139-1147. doi:10.3851/IMP1918

DOI
10.3851/IMP1918
Journal article

Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract

Else, L. J., Taylor, S., Back, D. J., & Khoo, S. H. (2011). Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract. ANTIVIRAL THERAPY, 16(8), 1149-1167. doi:10.3851/IMP1919

DOI
10.3851/IMP1919
Journal article

IFN-γ 874A&gt;T Genotype Is Associated With Higher CCR5 Expression in Peripheral Blood Mononuclear Cells From HIV plus Patients

Liptrott, N. J., Egan, D., Back, D. J., & Owen, A. (2011). IFN-γ 874A&gt;T Genotype Is Associated With Higher CCR5 Expression in Peripheral Blood Mononuclear Cells From HIV plus Patients. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 58(5), 442-445. doi:10.1097/QAI.0b013e318236441c

DOI
10.1097/QAI.0b013e318236441c
Journal article

Plasma and Intracellular Pharmacokinetics of Darunavir/Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals

Jackson, A., Watson, V., Back, D., Khoo, S., Liptrott, N., Egan, D., . . . Boffito, M. (2011). Plasma and Intracellular Pharmacokinetics of Darunavir/Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 58(5), 450-457. doi:10.1097/QAI.0b013e3182364c67

DOI
10.1097/QAI.0b013e3182364c67
Journal article

Plasma and Intracellular Pharmacokinetics of Darunavir/Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals

Jackson, A., Watson, V., Back, D., Khoo, S., Liptrott, N., Egan, D., . . . Boffito, M. (2011). Plasma and Intracellular Pharmacokinetics of Darunavir/Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals. JAIDS Journal of Acquired Immune Deficiency Syndromes, 58(5), 450-457. doi:10.1097/qai.0b013e3182364c67

DOI
10.1097/qai.0b013e3182364c67
Journal article

Should we switch to a 50-mg boosting dose of ritonavir for selected protease inhibitors?

Hill, A., Khoo, S., Boffito, M., & Back, D. (2011). Should we switch to a 50-mg boosting dose of ritonavir for selected protease inhibitors?. Journal of acquired immune deficiency syndromes (1999), 58(5), e137-e138. doi:10.1097/qai.0b013e318237ccae

DOI
10.1097/qai.0b013e318237ccae
Journal article

Challenges and opportunities for hepatitis C drug development in HIV-hepatitis C virus-co-infected patients.

Soriano, V., Sherman, K. E., Rockstroh, J., Dieterich, D., Back, D., Sulkowski, M., & Peters, M. (2011). Challenges and opportunities for hepatitis C drug development in HIV-hepatitis C virus-co-infected patients.. AIDS (London, England), 25(18), 2197-2208. doi:10.1097/qad.0b013e32834bbb90

DOI
10.1097/qad.0b013e32834bbb90
Journal article

Directly acting antivirals for hepatitis C and antiretrovirals: potential for drug-drug interactions.

Seden, K., & Back, D. (2011). Directly acting antivirals for hepatitis C and antiretrovirals: potential for drug-drug interactions.. Current opinion in HIV and AIDS, 6(6), 514-526. doi:10.1097/coh.0b013e32834b54dc

DOI
10.1097/coh.0b013e32834b54dc
Journal article

Cytochrome P450 2B6 (<i>CYP2B6</i>) and constitutive androstane receptor (<i>CAR</i>) polymorphisms are associated with early discontinuation of efavirenz-containing regimens

Wyen, C., Hendra, H., Siccardi, M., Platten, M., Jaeger, H., Harrer, T., . . . Owen, A. (2011). Cytochrome P450 2B6 (<i>CYP2B6</i>) and constitutive androstane receptor (<i>CAR</i>) polymorphisms are associated with early discontinuation of efavirenz-containing regimens. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 66(9), 2092-2098. doi:10.1093/jac/dkr272

DOI
10.1093/jac/dkr272
Journal article

Pharmacokinetics of Once-Daily Darunavir-Ritonavir and Atazanavir-Ritonavir over 72 Hours following Drug Cessation

Boffito, M., Jackson, A., Amara, A., Back, D., Khoo, S., Higgs, C., . . . Moyle, G. (2011). Pharmacokinetics of Once-Daily Darunavir-Ritonavir and Atazanavir-Ritonavir over 72 Hours following Drug Cessation. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55(9), 4218-4223. doi:10.1128/AAC.01747-10

DOI
10.1128/AAC.01747-10
Journal article

Genetic Variants of <i>ABCC10</i>, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction

Pushpakom, S. P., Liptrott, N. J., Rodriguez-Novoa, S., Labarga, P., Soriano, V., Albalater, M., . . . Owen, A. (2011). Genetic Variants of <i>ABCC10</i>, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction. JOURNAL OF INFECTIOUS DISEASES, 204(1), 145-153. doi:10.1093/infdis/jir215

DOI
10.1093/infdis/jir215
Journal article

Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction

Pushpakom, S. P., Liptrott, N. J., Rodríguez-Nóvoa, S., Labarga, P., Soriano, V., Albalater, M., . . . Owen, A. (2011). Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction. The Journal of Infectious Diseases, 204(1), 145-153. doi:10.1093/infdis/jir215

DOI
10.1093/infdis/jir215
Journal article

Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals

Schipani, A., Wyen, C., Mahungu, T., Hendra, H., Egan, D., Siccardi, M., . . . Back, D. J. (2011). Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 66(6), 1332-1339. doi:10.1093/jac/dkr087

DOI
10.1093/jac/dkr087
Journal article

Pharmacokinetic and safety profile of raltegravir and ribavirin, when dosed separately and together, in healthy volunteers.

Ashby, J., Garvey, L., Erlwein, O. W., Lamba, H., Weston, R., Legg, K., . . . Winston, A. (2011). Pharmacokinetic and safety profile of raltegravir and ribavirin, when dosed separately and together, in healthy volunteers.. The Journal of antimicrobial chemotherapy, 66(6), 1340-1345. doi:10.1093/jac/dkr093

DOI
10.1093/jac/dkr093
Journal article

Sequential Population Pharmacokinetic Modeling of Lopinavir and Ritonavir in Healthy Volunteers and Assessment of Different Dosing Strategies

Dickinson, L., Boffito, M., Back, D., Else, L., von Hentig, N., Davies, G., . . . Aarons, L. (2011). Sequential Population Pharmacokinetic Modeling of Lopinavir and Ritonavir in Healthy Volunteers and Assessment of Different Dosing Strategies. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55(6), 2775-2782. doi:10.1128/AAC.00887-10

DOI
10.1128/AAC.00887-10
Journal article

Cardiac Conduction Safety during Coadministration of Artemether-Lumefantrine and Lopinavir/Ritonavir in HIV-Infected Ugandan Adults.

Byakika-Kibwika, P., Lamorde, M., Lwabi, P., Nyakoojo, W. B., Okaba-Kayom, V., Mayanja-Kizza, H., . . . Merry, C. (2011). Cardiac Conduction Safety during Coadministration of Artemether-Lumefantrine and Lopinavir/Ritonavir in HIV-Infected Ugandan Adults.. Chemotherapy research and practice, 2011, 393976. doi:10.1155/2011/393976

DOI
10.1155/2011/393976
Journal article

Investigating variability in reported intracellular raltegravir concentrations: contribution of PBMC isolation methodology

Watson, V., Liptrott, N., Egan, D., Dickinson, L., Tjia, J., Reynolds, H., . . . Back, D. (2011). Investigating variability in reported intracellular raltegravir concentrations: contribution of PBMC isolation methodology. Poster session presented at the meeting of 12th International Workshop on Clinical Pharmacology of HIV Therapy. Miami, USA.

Poster

Pharmacokinetics and safety of the co-administration of the antiretroviral raltegravir and the lipid-lowering drug ezetimibe in healthy volunteers.

Jackson, A., D'Avolio, A., Watson, V., Bonora, S., Back, D., Taylor, J., . . . Boffito, M. (2011). Pharmacokinetics and safety of the co-administration of the antiretroviral raltegravir and the lipid-lowering drug ezetimibe in healthy volunteers.. The Journal of antimicrobial chemotherapy, 66(4), 885-889. doi:10.1093/jac/dkq546

DOI
10.1093/jac/dkq546
Journal article

Total and unbound lopinavir concentrations in the female genital tract of HIV-1 infected women during pregnancy

Else, L. J., Lyons, F., O'Shea, S., Costello, S., Mullen, J., Lechelt, M., . . . de Ruiter, A. (2011). Total and unbound lopinavir concentrations in the female genital tract of HIV-1 infected women during pregnancy. AIDS, 25(5), 722-725. doi:10.1097/QAD.0b013e3283445700

DOI
10.1097/QAD.0b013e3283445700
Journal article

Total and unbound lopinavir concentrations in the female genital tract of HIV-1 infected women during pregnancy.

Else, L., Lyons, F., O'shea, S., Costello, S., Mullen, J., Lechelt, M., . . . de Ruiter, A. (2011). Total and unbound lopinavir concentrations in the female genital tract of HIV-1 infected women during pregnancy.. AIDS, 25(5), 722-725.

Journal article

Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers.

Jackson, A., Hill, A., Puls, R., Else, L., Amin, J., Back, D., . . . Boffito, M. (2011). Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers.. The Journal of antimicrobial chemotherapy, 66(3), 635-640. doi:10.1093/jac/dkq468

DOI
10.1093/jac/dkq468
Journal article

Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

Lambert, J. S., Else, L. J., Jackson, V., Breiden, J., Gibbons, S., Dickinson, L., . . . Khoo, S. H. (2011). Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy. HIV MEDICINE, 12(3), 166-173. doi:10.1111/j.1468-1293.2010.00865.x

DOI
10.1111/j.1468-1293.2010.00865.x
Journal article

Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

Lambert, J. S., Else, L. J., Jackson, V., Breiden, J., Gibbons, S., Dickinson, L., . . . Khoo, S. H. (2011). Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy. HIV Medicine, 12(3), 166-173. doi:10.1111/j.1468-1293.2010.00865.x

DOI
10.1111/j.1468-1293.2010.00865.x
Journal article

Prevalence of Potential Drug-Drug Interactions Involving Antiretroviral Drugs in a Large Kenyan Cohort

Kigen, G., Kimaiyo, S., Nyandiko, W., Faragher, B., Sang, E., Jakait, B., . . . Khoo, S. H. (2011). Prevalence of Potential Drug-Drug Interactions Involving Antiretroviral Drugs in a Large Kenyan Cohort. PLOS ONE, 6(2). doi:10.1371/journal.pone.0016800

DOI
10.1371/journal.pone.0016800
Journal article

Raltegravir Is a Substrate for SLC22A6: a Putative Mechanism for the Interaction between Raltegravir and Tenofovir

Moss, D. M., Kwan, W. S., Liptrott, N. J., Smith, D. L., Siccardi, M., Khoo, S. H., . . . Owen, A. (2011). Raltegravir Is a Substrate for SLC22A6: a Putative Mechanism for the Interaction between Raltegravir and Tenofovir. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55(2), 879-887. doi:10.1128/AAC.00623-10

DOI
10.1128/AAC.00623-10
Journal article

. Pharmacokinetics and safety of the co-administration of the antiretroviral raltegravir and the lipid-lowering drug ezetimibe in healthy volunteers

Jackson, A., D'Avolio, A., Watson, V., Bonora, S., Back, D., Taylor, J., . . . Boffito, M. (2011). . Pharmacokinetics and safety of the co-administration of the antiretroviral raltegravir and the lipid-lowering drug ezetimibe in healthy volunteers. Journal of Antimicrobial Chemotherapy, 66, 885-889.

Journal article

. Pharmacokinetic and safety profile of raltegravir and ribavirin when dosed separately and together in healthy volunteers

Ashby, J., Garvey, L., Erlwein, O. W., Lamba, H., Weston, R., Legg, K., . . . Winston, A. (2011). . Pharmacokinetic and safety profile of raltegravir and ribavirin when dosed separately and together in healthy volunteers. Journal of Antimicrobial Chemotherapy, 66, 1340-1345.

Journal article

Adipogenic gene variants in patients with HIV-associated lipodystrophy

Pushpakom, S. P., Owen, A., Vilar, F. J., Castro, H., Dunn, D. T., Back, D. J., & Pirmohamed, M. (2011). Adipogenic gene variants in patients with HIV-associated lipodystrophy. PHARMACOGENETICS AND GENOMICS, 21(2), 76-83. doi:10.1097/FPC.0b013e328342a917

DOI
10.1097/FPC.0b013e328342a917
Journal article

Ageing with HIV: medication use and risk for potential drug-drug interactions.

Marzolini, C., Back, D., Weber, R., Furrer, H., Cavassini, M., Calmy, A., . . . Swiss HIV Cohort Study Members. (2011). Ageing with HIV: medication use and risk for potential drug-drug interactions.. The Journal of antimicrobial chemotherapy, 66(9), 2107-2111. doi:10.1093/jac/dkr248

DOI
10.1093/jac/dkr248
Journal article

Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS.

Liptrott, N. J., Pushpakom, S., Wyen, C., Fatkenheur, G., Hoffmann, C., Mauss, S., . . . Owen, A. (2011). Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS.. Pharmacogenetics and genomics.

Journal article

Directly acting antivirals for hepatitis C and antiretrovirals: potential for drug-drug interactions.

Seden, K., & Back, D. (2011). Directly acting antivirals for hepatitis C and antiretrovirals: potential for drug-drug interactions.. Current Opinion in HIV and AIDS, 6, 514-526.

Journal article

Nevirapine pharmacokinetics when initiated at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin.

Lamorde, M., Byakika-Kibwika, P., Okaba-Kayom, V., Ryan, M., Coakley, P., Boffito, M., . . . Merry, C. (2011). Nevirapine pharmacokinetics when initiated at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin.. The Journal of antimicrobial chemotherapy, 66(1), 180-183. doi:10.1093/jac/dkq411

DOI
10.1093/jac/dkq411
Journal article

Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers.

Jackson, A., Hill, A., Puls, R., Else, L., Amin, J., Back, D., . . . Boffito, M. (2011). Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers.. Journal of Antimicrobial Chemotherapy., 66, 635-640.

Journal article

Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).

Else, L. J., Taylor, S., Back, D. J., & Khoo, S. H. (2011). Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).. Antiviral Therapy, 16, 1139-1147.

Journal article

Pharmacokinetics of darunavir/ritonavir and atazanavir/ritonavir once daily over 72 hours following drug cessation

Boffito, M., Jackson, A., Amara, A., Back, D., Khoo, S., Higgs, C., . . . Moyle, G. (2011). Pharmacokinetics of darunavir/ritonavir and atazanavir/ritonavir once daily over 72 hours following drug cessation. Antimicrobial Agents and Chemotherapy, 55, 4218-4223.

Journal article

Plasma and Intracellular (Peripheral Blood Mononuclear Cells) Pharmacokinetics of Once-Daily Raltegravir (800 Milligrams) in HIV-Infected Patients

Molto, J., Valle, M., Back, D., Cedeno, S., Watson, V., Liptrott, N., . . . Clotet, B. (2011). Plasma and Intracellular (Peripheral Blood Mononuclear Cells) Pharmacokinetics of Once-Daily Raltegravir (800 Milligrams) in HIV-Infected Patients. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 55(1), 72-75. doi:10.1128/AAC.00789-10

DOI
10.1128/AAC.00789-10
Journal article

Plasma and intracellular (PBMCs) pharmacokinetics of once-daily raltegravir (800 mg) in HIV-infected patients.

Molto, J., Valle, M., Back, D., Cedeno, S., Watson, V., Liptrott, N., . . . Clotet, B. (2011). Plasma and intracellular (PBMCs) pharmacokinetics of once-daily raltegravir (800 mg) in HIV-infected patients.. Antimicrobial Agents & Chemotherapy, 55, 72-75.

Journal article

Plasma and intracellular pharmacokinetics of darunavir/ritonavir once daily and raltegravir once and twice daily in HIV-infected individuals

Jackson, A., Watson, V., Back, D., Khoo, S., Liptrott, N., Egan, D., . . . Boffito, M. (2011). Plasma and intracellular pharmacokinetics of darunavir/ritonavir once daily and raltegravir once and twice daily in HIV-infected individuals. of Acquired Immune Deficiency Syndrome, 58, 450-457.

Journal article

Sequential population pharmacokinetic modelling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies.

Dickinson, L., Boffito, M., Back, D., Else, L., von Hentig, N., Davies, G., . . . Aarons, L. (2011). Sequential population pharmacokinetic modelling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies.. Antimicrob Agents & Chemotherapy, 55, 2775-2782.

Journal article

Total and unbound lopinavir concentrations in the female genital tract of HIV-1 infected women during pregnancy

Else, L. J., Lyons, F., O'Shea, S., Costello, S., Mullen, J., Lechelt, M., . . . de Ruiter, A. (2011). Total and unbound lopinavir concentrations in the female genital tract of HIV-1 infected women during pregnancy. AIDS, 25, 722-725.

Journal article

2010

Grapefruit-Drug Interactions

Seden, K., Dickinson, L., Khoo, S., & Back, D. (2010). Grapefruit-Drug Interactions. Drugs, 70(18), 2373-2407. doi:10.2165/11585250-000000000-00000

DOI
10.2165/11585250-000000000-00000
Journal article

Grapefruit-drug interactions.

Seden, K., Dickinson, L., Khoo, S., & Back, D. (2010). Grapefruit-drug interactions.. Drugs, 70(18), 2373-2407. doi:10.2165/11585250-000000000-00000

DOI
10.2165/11585250-000000000-00000
Journal article

Effect of boosted fosamprenavir or lopinavir-based combinations on whole-body insulin sensitivity and lipids in treatment-naive HIV-type-1-positive men

Randell, P. A., Jackson, A. G., Boffito, M., Back, D. J., Tjia, J. F., Taylor, J., . . . Moyle, G. J. (2010). Effect of boosted fosamprenavir or lopinavir-based combinations on whole-body insulin sensitivity and lipids in treatment-naive HIV-type-1-positive men. ANTIVIRAL THERAPY, 15(8), 1125-1132. doi:10.3851/IMP1675

DOI
10.3851/IMP1675
Journal article

Maraviroc is a substrate for OATP1B1 <i>in vitro</i> and maraviroc plasma concentrations are influenced by SLCO1B1 521 T&gt;C polymorphism

Siccardi, M., D'Avolio, A., Nozza, S., Simiele, M., Baietto, L., Stefani, F. R., . . . Owen, A. (2010). Maraviroc is a substrate for OATP1B1 <i>in vitro</i> and maraviroc plasma concentrations are influenced by SLCO1B1 521 T&gt;C polymorphism. PHARMACOGENETICS AND GENOMICS, 20(12), 759-765. doi:10.1097/FPC.0b013e3283402efb

DOI
10.1097/FPC.0b013e3283402efb
Journal article

Pharmacokinetic evaluation of etravirine

Dickinson, L., Khoo, S., & Back, D. (2010). Pharmacokinetic evaluation of etravirine. Expert Opinion on Drug Metabolism &amp; Toxicology, 6(12), 1575-1585. doi:10.1517/17425255.2010.535811

DOI
10.1517/17425255.2010.535811
Journal article

Pharmacokinetic evaluation of etravirine.

Dickinson, L., Khoo, S., & Back, D. (2010). Pharmacokinetic evaluation of etravirine.. Expert opinion on drug metabolism & toxicology, 6(12), 1575-1585. doi:10.1517/17425255.2010.535811

DOI
10.1517/17425255.2010.535811
Journal article

Pharmacokinetic evaluation of etravirine.

Dickinson, L., Khoo, S., & Back, D. (2010). Pharmacokinetic evaluation of etravirine.. Expert opinion on drug metabolism & toxicology, 6(12), 1575-1585.

Journal article

Population Pharmacokinetic Modeling of the Association between 63396C→T Pregnane X Receptor Polymorphism and Unboosted Atazanavir Clearance

Schipani, A., Siccardi, M., D'Avolio, A., Baietto, L., Simiele, M., Bonora, S., . . . Owen, A. (2010). Population Pharmacokinetic Modeling of the Association between 63396C→T Pregnane X Receptor Polymorphism and Unboosted Atazanavir Clearance. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(12), 5242-5250. doi:10.1128/AAC.00781-10

DOI
10.1128/AAC.00781-10
Journal article

Population Pharmacokinetic Modeling of the Association between 63396C→T Pregnane X Receptor Polymorphism and Unboosted Atazanavir Clearance

Schipani, A., Siccardi, M., D'Avolio, A., Baietto, L., Simiele, M., Bonora, S., . . . Owen, A. (2010). Population Pharmacokinetic Modeling of the Association between 63396C→T Pregnane X Receptor Polymorphism and Unboosted Atazanavir Clearance. Antimicrobial Agents and Chemotherapy, 54(12), 5242-5250. doi:10.1128/aac.00781-10

DOI
10.1128/aac.00781-10
Journal article

Suboptimal Nevirapine Steady-State Pharmacokinetics During Intrapartum Compared With Postpartum in HIV-1-Seropositive Ugandan Women

Lamorde, M., Byakika-Kibwika, P., Okaba-Kayom, V., Flaherty, J. P., Boffito, M., Namakula, R., . . . Scarsi, K. K. (2010). Suboptimal Nevirapine Steady-State Pharmacokinetics During Intrapartum Compared With Postpartum in HIV-1-Seropositive Ugandan Women. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 55(3), 345-350. doi:10.1097/QAI.0b013e3181e9871b

DOI
10.1097/QAI.0b013e3181e9871b
Journal article

Darunavir concentrations exceed the protein-corrected EC<sub>50</sub> for wild-type HIV in the semen of HIV-1-infected men

Taylor, S., Jayasuriya, A. N., Berry, A., Gilleran, G., Dufty, N. E., Else, L., . . . Smit, E. J. (2010). Darunavir concentrations exceed the protein-corrected EC<sub>50</sub> for wild-type HIV in the semen of HIV-1-infected men. AIDS, 24(16), 2574-2577. doi:10.1097/QAD.0b013e32833ead18

DOI
10.1097/QAD.0b013e32833ead18
Journal article

Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds

Else, L., Watson, V., Tjia, J., Hughes, A., Siccardi, M., Khoo, S., & Back, D. (2010). Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 878(19), 1455-1465. doi:10.1016/j.jchromb.2010.03.036

DOI
10.1016/j.jchromb.2010.03.036
Journal article

Recognition of Risk for Clinically Significant Drug Interactions among HIV-Infected Patients Receiving Antiretroviral Therapy

Evans-Jones, J. G., Cottle, L. E., Back, D. J., Gibbons, S., Beeching, N. J., Carey, P. B., & Khoo, S. H. (2010). Recognition of Risk for Clinically Significant Drug Interactions among HIV-Infected Patients Receiving Antiretroviral Therapy. CLINICAL INFECTIOUS DISEASES, 50(10), 1419-1421. doi:10.1086/652149

DOI
10.1086/652149
Journal article

The effects of a nucleoside-sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1-infected patients.

Garvey, L., Latch, N., Erlwein, O. W., Mackie, N. E., Walsh, J., Scullard, G., . . . Winston, A. (2010). The effects of a nucleoside-sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1-infected patients.. Antiviral therapy, 15(2), 213-218. doi:10.3851/imp1517

DOI
10.3851/imp1517
Journal article

New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals.

Seden, K., Back, D., & Khoo, S. (2010). New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals.. The Journal of antimicrobial chemotherapy, 65(6), 1079-1085. doi:10.1093/jac/dkq086

DOI
10.1093/jac/dkq086
Journal article

Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes

Janneh, O., Bray, P. G., Jones, E., Wyen, C., Chiba, P., Back, D. J., & Khoo, S. H. (2010). Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 65(5), 906-916. doi:10.1093/jac/dkq082

DOI
10.1093/jac/dkq082
Journal article

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by <i>SLCO1B1</i> polymorphisms

Hartkoorn, R. C., San Kwan, W., Shallcross, V., Chaikan, A., Liptrott, N., Egan, D., . . . Owen, A. (2010). HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by <i>SLCO1B1</i> polymorphisms. PHARMACOGENETICS AND GENOMICS, 20(2), 112-120. doi:10.1097/FPC.0b013e328335b02d

DOI
10.1097/FPC.0b013e328335b02d
Journal article

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms

Hartkoorn, R. C., Kwan, W. S., Shallcross, V., Chaikan, A., Liptrott, N., Egan, D., . . . Owen, A. (2010). HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms. Pharmacogenetics and Genomics, 20(2), 112-120. doi:10.1097/fpc.0b013e328335b02d

DOI
10.1097/fpc.0b013e328335b02d
Journal article

Association of ABCC10 Polymorphisms with Nevirapine Plasma Concentrations in the German Competence Network for HIV/AIDS

Liptrott, N. J., Pushpakom, S., Wyen, C., Rockstroh, J., Mauss, S., Knechten, H., . . . Owen, A. (2010). Association of ABCC10 Polymorphisms with Nevirapine Plasma Concentrations in the German Competence Network for HIV/AIDS. In 17th Conference on Retroviruses and Opportunistic Infections (pp. 286). San Francisco: Conference on Retroviruses and Opportunistic Infections.

Conference Paper

Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 cells and primary human lymphocytes

Janneh, O., Bray, P. G., Jones, E., Wyen, C., Chiba, P., Back, D. J., & Khoo, S. H. (2010). Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 cells and primary human lymphocytes. Journal of Antimicrobial Chemotherapy, 65, 906-916.

Journal article

Darunavir concentrations exfeed the protein-corrected EC50 for wild-type HIV in the semen of HIV-1 infected men

Taylor, S., Jayasuriya, A. N., Berry, A., Gilleran, G., Dufty, N. E., Else, L., . . . Smit, E. J. (2010). Darunavir concentrations exfeed the protein-corrected EC50 for wild-type HIV in the semen of HIV-1 infected men. AIDS, 24, 2583-2587.

Journal article

Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells

Martin, P., Riley, R., Thompson, P., Williams, D., Back, D., & Owen, A. (2010). Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells. ACTA PHARMACOLOGICA SINICA, 31(1), 51-65. doi:10.1038/aps.2009.187

DOI
10.1038/aps.2009.187
Journal article

Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells

Martin, P., Riley, R., Thompson, P., Williams, D., Back, D., & Owen, A. (2010). Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells. Acta Pharmacologica, 31, 51-65.

Journal article

Genetic Variants of ABCC10 Are Associated with Kidney Tubular Dysfunction in Patients Treated with Tenofovir-containing Regimens

Pushpakom, S., Liptrott, N. J., Rodríguez-Nóvoa, S., Labarga, P., Soriano, V., Albalater, M., . . . Owen, A. (2010). Genetic Variants of ABCC10 Are Associated with Kidney Tubular Dysfunction in Patients Treated with Tenofovir-containing Regimens. In 17th Conference on Retroviruses and Opportunistic Infections (pp. 352). San Francisco: Conference on Retroviruses and Opportunistic Infections.

Conference Paper

Grapefruit juice drug interactions

Seden, K., Dickinson, L., Khoo, S., & Back, D. (2010). Grapefruit juice drug interactions. Drugs, 70(18), 2373-2407.

Journal article

Investigation of low-dose ritonavir on human peripheral blood mononuclear cells using gene expression whole genome microarrays.

Yilmaz, S., Boffito, M., Collot-Teixeira, S., De Lorenzo, F., Waters, L., Fletcher, C., . . . McGregor, J. L. (2010). Investigation of low-dose ritonavir on human peripheral blood mononuclear cells using gene expression whole genome microarrays.. Genomics, 96(1), 57-65. doi:10.1016/j.ygeno.2010.03.011

DOI
10.1016/j.ygeno.2010.03.011
Journal article

Nevirapine pharmacokinetics when inititate at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin

Lamorde, M., Byakika-Kbwika, P., Okaba-Kayom, V., Ryan, M., Coakley, P., Boffito, M., . . . Merry, C. (2010). Nevirapine pharmacokinetics when inititate at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin. Journal of Antimicrobial Chemotherapy, 66, 180-183.

Journal article

Pharmacokinetic evaluation of etravirine

Dickinson, L., Khoo, S., & Back, D. (2010). Pharmacokinetic evaluation of etravirine. Expert Opinion in Drug Metabolism & Toxicology, 6, 1575-1585.

Journal article

Pharmacokinetics and drug-drug interactions of antiretrovirals: an update.

Dickinson, L., Khoo, S., & Back, D. (2010). Pharmacokinetics and drug-drug interactions of antiretrovirals: an update.. Antiviral research, 85(1), 176-189.

Journal article

Pharmacokinetics and drug-drug interactions of antiretrovirals: an update.

Dickinson, L., Khoo, S., & Back, D. (2010). Pharmacokinetics and drug-drug interactions of antiretrovirals: an update.. Antiviral research, 85(1), 176-189. doi:10.1016/j.antiviral.2009.07.017

DOI
10.1016/j.antiviral.2009.07.017
Journal article

Pharmacokinetics and drug–drug interactions of antiretrovirals: An update

Dickinson, L., Khoo, S., & Back, D. (2010). Pharmacokinetics and drug–drug interactions of antiretrovirals: An update. Antiviral Research, 85(1), 176-189. doi:10.1016/j.antiviral.2009.07.017

DOI
10.1016/j.antiviral.2009.07.017
Journal article

Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers

Jackson, A., Hill, A., Puls, R., Else, L., Amin, J., Back, D., . . . Boffito, M. (2010). Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers. Journal of Antimicrobial Chemotherapy.

Journal article

Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers.

Jackson, A., Hill, A., Puls, R., Else, L., Amin, J., Back, D., . . . Boffito, M. (2010). Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers.. J Antimicrob Chemother..

Journal article

Plasma and intracellular (PBMCs) pharmacokinetics of once-daily raltegravir (800 mg) in HIV-infected patients

Molto, J., Valle, M., Back, D., Cedeno, S., Watson, V., Liptrott, N., . . . Clotet, B. (2010). Plasma and intracellular (PBMCs) pharmacokinetics of once-daily raltegravir (800 mg) in HIV-infected patients. Antimicrobial Agents & Chemotherapy.

Journal article

Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study.

Marzolini, C., Elzi, L., Gibbons, S., Weber, R., Fux, C., Furrer, H., . . . Swiss HIV Cohort Study. (2010). Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study.. Antiviral therapy, 15(3), 413-423. doi:10.3851/imp1540

DOI
10.3851/imp1540
Journal article

Raltegraivr is a substrate for SLC22A6: A putative mechanism for the interaction between raltegravir and tenofovir

Moss, D. M., Kwan, W. S., Liptortt, N. J., Smith, D. L., Siccardi, M., Khoo, S. H., . . . Owen, A. (2010). Raltegraivr is a substrate for SLC22A6: A putative mechanism for the interaction between raltegravir and tenofovir. Antimicrob Agents & Chemotherapy.

Journal article

Raltegravir Is a Substrate for the Influx Transporters OAT1 and PEPT1 and the Efflux Transporter Pgp, but Is Not Transported by OATP1A2, OATP1B1, OATP1B3, OCT1, NTCP, or PEPT2

Moss, D., Kwan, W., Liptrott, N., Siccardi, M., Anstee, D., Khoo, S., . . . Owen, A. (2010). Raltegravir Is a Substrate for the Influx Transporters OAT1 and PEPT1 and the Efflux Transporter Pgp, but Is Not Transported by OATP1A2, OATP1B1, OATP1B3, OCT1, NTCP, or PEPT2. In 17th Conference on Retroviruses and Opportunistic Infections (pp. 293). San Francisco: Conference on Retroviruses and Opportunistic Infections.

Conference Paper

Raltegravir is a substrate for SLC22A6: A putative mechanism for the interaction between raltegravir and tenofovir

Moss, D. M., Kwan, W. S., Liptrott, N. J., Smith, D. L., Siccardi, M., Khoo, S. H., . . . Owen, A. (2010). Raltegravir is a substrate for SLC22A6: A putative mechanism for the interaction between raltegravir and tenofovir. Antimicrob Agents Chemother, 55(2), 879-887.

Journal article

Suboptimal nevirapine steady-state pharmacokinetics during intrapartum compared with postpartum in HIV-1 seropositive Ugandan women

Lamorde, M., Byakika-Kibwika, P., Okaba-Kayom, V., Flaherty, J. P., Boffito, M., Namakula, R., . . . Scarsi, K. K. (2010). Suboptimal nevirapine steady-state pharmacokinetics during intrapartum compared with postpartum in HIV-1 seropositive Ugandan women. Journal of Acquired Immune Deficiency Syndrome, 55, 345-350.

Journal article

Swiss Cohort Study. Prevelance of codedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study

Marzolini, C., Elzi, L., Gibbons, S., Weber, R., Fux, C., Furer, H., . . . Battegay, M. (2010). Swiss Cohort Study. Prevelance of codedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study. Antiviral Therapy, 15, 413-423.

Journal article

The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes

Janneh, O., Owen, A., Bray, P. G., Back, D. J., & Pirmohamed, M. (2010). The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes. British Journal of Pharmacology, 159, 484-493.

Journal article

The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes

Janneh, O., Owen, A., Bray, P. G., Back, D. J., & Pirmohamed, M. (2010). The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes. BRITISH JOURNAL OF PHARMACOLOGY, 159(2), 484-493. doi:10.1111/j.1476-5381.2009.00552.x

DOI
10.1111/j.1476-5381.2009.00552.x
Journal article

The effects of a nucleoside sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1 infected patients

Garvey, L., Latch, N., Erlwein, O. W., Mackie, N. E., Walsh, J., Scullard, G., . . . Winston, A. (2010). The effects of a nucleoside sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1 infected patients. Antiviral Therapy, 15, 213-218.

Journal article

The effects of a nucleoside-sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1-infected patients.

Garvey, L., Latch, N., Erlwein, O. W., Mackie, N. E., Walsh, J., Scullard, G., . . . Winston, A. (2010). The effects of a nucleoside-sparing antiretroviral regimen on the pharmacokinetics of ritonavir-boosted darunavir in HIV type-1-infected patients.. Antiviral therapy, 15(2), 213-218.

Journal article

Validation of a rapid and sensitive high-performance liquid chromatography-tandme mass spectrometry (HPLC-MS/MS) assay for the simulataneous determination of existing and new antiretroviral compounds

Else, L., Watson, V., Tjia, J., Hughes, A., Siccardi, M., Khoo, S., & Back, D. (2010). Validation of a rapid and sensitive high-performance liquid chromatography-tandme mass spectrometry (HPLC-MS/MS) assay for the simulataneous determination of existing and new antiretroviral compounds. Journal of Chromatogr B Analytical Technology Biomedical Life Sciences, 878, 1455-1465.

Journal article

2009

P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir

Janneh, O., Anwar, T., Jungbauer, C., Kopp, S., Khoo, S. H., Back, D. J., & Chiba, P. (2009). P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir. ANTIVIRAL THERAPY, 14(7), 965-974. doi:10.3851/IMP1399

DOI
10.3851/IMP1399
Journal article

Pharmacokinetics of nevirapine in HIV-infected children with and without malnutrition receiving divided adult fixed-dose combination tablets.

Pollock, L., Else, L., Poerksen, G., Molyneux, E., Moons, P., Walker, S., . . . Khoo, S. (2009). Pharmacokinetics of nevirapine in HIV-infected children with and without malnutrition receiving divided adult fixed-dose combination tablets.. The Journal of antimicrobial chemotherapy, 64(6), 1251-1259. doi:10.1093/jac/dkp358

DOI
10.1093/jac/dkp358
Journal article

Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes

Janneh, O., Chandler, B., Hartkoorn, R., Kwan, W. S., Jenkinson, C., Evans, S., . . . Khoo, S. (2009). Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes. J Antimicrob Chemother, 64(5), 1002-1007.

Journal article

Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes

Janneh, O., Chandler, B., Hartkoorn, R., Kwan, W. S., Jenkinson, C., Evans, S., . . . Khoo, S. H. (2009). Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 64(5), 1002-1007. doi:10.1093/jac/dkp335

DOI
10.1093/jac/dkp335
Journal article

Cytochrome P450 2B6 516G-->T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population

Mahungu, T., Smith, C., Turner, F., Egan, D., Youle, M., Johnson, M., . . . Owen, A. (2009). Cytochrome P450 2B6 516G-->T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population. HIV Med, 10(5), 310-317.

Journal article

Pharmacokinetics and safety of etravirine administered once or twice daily after 2 weeks treatment with efavirenz in healthy volunteers.

Boffito, M., Jackson, A., Lamorde, M., Back, D., Watson, V., Taylor, J., . . . Pozniak, A. (2009). Pharmacokinetics and safety of etravirine administered once or twice daily after 2 weeks treatment with efavirenz in healthy volunteers.. Journal of acquired immune deficiency syndromes (1999), 52(2), 222-227. doi:10.1097/qai.0b013e3181b061d0

DOI
10.1097/qai.0b013e3181b061d0
Journal article

Maraviroc: pharmacokinetics and drug interactions

Abel, S., Back, D. J., & Vourvahis, M. (2009). Maraviroc: pharmacokinetics and drug interactions. ANTIVIRAL THERAPY, 14(5), 607-618. Retrieved from https://www.webofscience.com/

Journal article

Intracellular 'boosting' of darunavir using known transport inhibitors in primary PBMC

Kwan, W. S., Janneh, O., Hartkoorn, R., Chandler, B., Khoo, S., Back, D., & Owen, A. (2009). Intracellular 'boosting' of darunavir using known transport inhibitors in primary PBMC. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 68(3), 375-380. doi:10.1111/j.1365-2125.2009.03462.x

DOI
10.1111/j.1365-2125.2009.03462.x
Journal article

Intracellular 'boosting' of darunavir using known transport inhibitors in primary PBMC

Kwan, W. S., Janneh, O., Hartkoorn, R., Chandler, B., Khoo, S., Back, D., & Owen, A. (2009). Intracellular 'boosting' of darunavir using known transport inhibitors in primary PBMC. Br J Clin Pharmacol, 68(3), 375-380.

Journal article

The Relationships of ABCB1 3435C&gt;T and CYP2B6 516G&gt;T With High-Density Lipoprotein Cholesterol in HIV-Infected Patients Receiving Efavirenz

Mahungu, T. W., Nair, D., Smith, C. J., Egan, D., Youle, M., Johnson, M. A., . . . Owen, A. (2009). The Relationships of ABCB1 3435C&gt;T and CYP2B6 516G&gt;T With High-Density Lipoprotein Cholesterol in HIV-Infected Patients Receiving Efavirenz. CLINICAL PHARMACOLOGY & THERAPEUTICS, 86(2), 204-211. doi:10.1038/clpt.2009.78

DOI
10.1038/clpt.2009.78
Journal article

Antiretroviral drug interactions: often unrecognized, frequently unavoidable, sometimes unmanageable.

Seden, K., Back, D., & Khoo, S. (2009). Antiretroviral drug interactions: often unrecognized, frequently unavoidable, sometimes unmanageable.. The Journal of antimicrobial chemotherapy, 64(1), 5-8. doi:10.1093/jac/dkp152

DOI
10.1093/jac/dkp152
Journal article

Etravirine plasma levels in a patient with decompensated liver disease.

Aboud, M., Castelino, S., Back, D., & Kulasegaram, R. (2009). Etravirine plasma levels in a patient with decompensated liver disease.. AIDS (London, England), 23(10), 1293-1295. doi:10.1097/qad.0b013e32832c9fb6

DOI
10.1097/qad.0b013e32832c9fb6
Journal article

Predictors of Kidney Tubular Dysfunction in HIV-Infected Patients Treated with Tenofovir: A Pharmacogenetic Study

Rodriguez-Novoa, S., Labarga, P., Soriano, V., Egan, D., Albalater, M., Morello, J., . . . Owen, A. (2009). Predictors of Kidney Tubular Dysfunction in HIV-Infected Patients Treated with Tenofovir: A Pharmacogenetic Study. CLINICAL INFECTIOUS DISEASES, 48(11), E108-E116. doi:10.1086/598507

DOI
10.1086/598507
Journal article

Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers

Dickinson, L., Boffito, M., Back, D., Waters, L., Else, L., Davies, G., . . . Aarons, L. (2009). Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 63(6), 1233-1243. doi:10.1093/jac/dkp102

DOI
10.1093/jac/dkp102
Journal article

Integrase as a Novel Target for the Inhibition of Human Immunodeficiency Virus Type 1 Infection: Current Status and Future Perspectives

Vandekerckhove, L. P. R., Christ, F., Debyser, Z., Owen, A., Back, D., Voet, A., . . . Vogelaers, D. (2009). Integrase as a Novel Target for the Inhibition of Human Immunodeficiency Virus Type 1 Infection: Current Status and Future Perspectives. In ANTIVIRAL RESEARCH: STRATEGIES IN ANTIVIRAL DRUG DISCOVERY (pp. 71-+). Retrieved from https://www.webofscience.com/

Chapter

Cytochrome P450 2B6 516G→T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population

Mahungu, T. W., Smith, C. J., Turner, F., Egan, D., Youle, M., Johnson, M. A., . . . Owen, A. (2009). Cytochrome P450 2B6 516G→T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population. HIV MEDICINE, 10(5), 310-317. doi:10.1111/j.1468-1293.2008.00689.x

DOI
10.1111/j.1468-1293.2008.00689.x
Journal article

Impact of different low-dose ritonavir regimens on lipids, CD36, and adipophilin expression.

Collot-Teixeira, S., De Lorenzo, F., Waters, L., Fletcher, C., Back, D., Mandalia, S., . . . Boffito, M. (2009). Impact of different low-dose ritonavir regimens on lipids, CD36, and adipophilin expression.. Clinical pharmacology and therapeutics, 85(4), 375-378. doi:10.1038/clpt.2008.243

DOI
10.1038/clpt.2008.243
Journal article

The impact of pharmacogenetics on HIV therapy

Mahungu, T. W., Johnson, M. A., Owen, A., & Back, D. J. (2009). The impact of pharmacogenetics on HIV therapy. INTERNATIONAL JOURNAL OF STD & AIDS, 20(3), 145-151. doi:10.1258/ijsa.2008.008369

DOI
10.1258/ijsa.2008.008369
Journal article

The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC

Liptrott, N. J., Penny, M., Bray, P. G., Sathish, J., Khoo, S. H., Back, D. J., & Owen, A. (2009). The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC. British Journal of Pharmacology, 156(3), 497-508. doi:10.1111/j.1476-5381.2008.00050.x

DOI
10.1111/j.1476-5381.2008.00050.x
Journal article

The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC

Liptrott, N. J., Penny, M., Bray, P. G., Sathish, J., Khoo, S. H., Back, D. J., & Owen, A. (2009). The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC. BRITISH JOURNAL OF PHARMACOLOGY, 156(3), 497-508. doi:10.1111/j.1476-5381.2008.00050.x

DOI
10.1111/j.1476-5381.2008.00050.x
Journal article

Differences in the pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons

Dickinson, L., Khoo, S., & Back, D. (2009). Differences in the pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons. Current Opinion in HIV & AIDS, (in pr.

Journal article

Drug-Drug Interactions Involving Antiretrovirals

Seden, K., Back, D. J., & Khoo, S. H. (2009). Drug-Drug Interactions Involving Antiretrovirals. Journal of Antimicrobial Chemotherapy, (in pr.

Journal article

Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: a pharmacogenetic study

Rodriguez-Novoa, S., Labarga, P., Soriano, V., Egan, D., Albalater, M., Morello, J., . . . Owen, A. (2009). Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: a pharmacogenetic study. Clin Infect Dis, 48(11), e108-e116.

Journal article

2008

Detection of ABCC2, CYP2B6 and CYP3A4 in human peripheral blood mononuclear cells using flow cytometry

Liprott, N. J., Khoo, S. H., Back, D. J., & Owen, A. (2008). Detection of ABCC2, CYP2B6 and CYP3A4 in human peripheral blood mononuclear cells using flow cytometry. JOURNAL OF IMMUNOLOGICAL METHODS, 339(2), 270-274. doi:10.1016/j.jim.2008.09.010

DOI
10.1016/j.jim.2008.09.010
Journal article

Pharmacokinetics of atazanavir/ritonavir once daily and lopinavir/ritonavir twice and once daily over 72 h following drug cessation.

Boffito, M., Else, L., Back, D., Taylor, J., Khoo, S., Sousa, M., . . . Moyle, G. (2008). Pharmacokinetics of atazanavir/ritonavir once daily and lopinavir/ritonavir twice and once daily over 72 h following drug cessation.. Antiviral therapy, 13(7), 901-907. doi:10.1177/135965350801300702

DOI
10.1177/135965350801300702
Journal article

Population pharmacokinetics of ritonavir-boosted saquinavir regimens in HIV-infected individuals.

Dickinson, L., Boffito, M., Back, D., Khoo, S., Pozniak, A. L., Mugyenyi, P., . . . Aarons, L. J. (2008). Population pharmacokinetics of ritonavir-boosted saquinavir regimens in HIV-infected individuals.. The Journal of antimicrobial chemotherapy, 62(6), 1344-1355.

Journal article

Population pharmacokinetics of ritonavir-boosted saquinavir regimens in HIV-infected individuals

Dickinson, L., Boffito, M., Back, D. J., Khoo, S. H., Pozniak, A. L., Mugyenyi, P., . . . Aarons, L. J. (2008). Population pharmacokinetics of ritonavir-boosted saquinavir regimens in HIV-infected individuals. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 62(6), 1344-1355. doi:10.1093/jac/dkn399

DOI
10.1093/jac/dkn399
Journal article

Association of a single-nucleotide polymorphism in the pregnane X receptor (<i>PXR</i> 63396C→T) with reduced concentrations of unboosted atazanavir

Siccardi, M., D'Avolio, A., Baietto, L., Gibbons, S., Sciandra, M., Colucci, D., . . . Owen, A. (2008). Association of a single-nucleotide polymorphism in the pregnane X receptor (<i>PXR</i> 63396C→T) with reduced concentrations of unboosted atazanavir. CLINICAL INFECTIOUS DISEASES, 47(9), 1222-1225. doi:10.1086/592304

DOI
10.1086/592304
Journal article

Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir

Janneh, O., Hartkoorn, R. C., Jones, E., Owen, A., Ward, S. A., Davey, R., . . . Khoo, S. H. (2008). Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir. BRITISH JOURNAL OF PHARMACOLOGY, 155(6), 875-883. doi:10.1038/bjp.2008.320

DOI
10.1038/bjp.2008.320
Journal article

Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients.

Moltó, J., Santos, J. R., Pérez-Alvarez, N., Cedeño, S., Miranda, C., Khoo, S., . . . Clotet, B. (2008). Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients.. Antimicrobial agents and chemotherapy, 52(11), 3928-3932. doi:10.1128/aac.00520-08

DOI
10.1128/aac.00520-08
Journal article

Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP

Sankatsing, S. U. C., Prins, J. M., Yong, S. -L. L., Roelofsen, J., van Kuilenburg, A. B. P., Kewn, S., . . . ten Berge, I. J. M. (2008). Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP. TRANSPLANT INTERNATIONAL, 21(11), 1066-1071. doi:10.1111/j.1432-2277.2008.00739.x

DOI
10.1111/j.1432-2277.2008.00739.x
Journal article

Steady-state pharmacokinetic comparison of generic and branded formulations of stavudine, lamivudine and nevirapine in HIV-infected Ugandan adults.

Byakika-Kibwika, P., Lamorde, M., Kalemeera, F., D'Avolio, A., Mauro, S., Di Perri, G., . . . Merry, C. (2008). Steady-state pharmacokinetic comparison of generic and branded formulations of stavudine, lamivudine and nevirapine in HIV-infected Ugandan adults.. The Journal of antimicrobial chemotherapy, 62(5), 1113-1117. doi:10.1093/jac/dkn290

DOI
10.1093/jac/dkn290
Journal article

HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options

Mallewa, J. E., Wilkins, E., Vilar, J., Mallewa, M., Doran, D., Back, D., & Pirmohamed, M. (2008). HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 62(4), 648-660. doi:10.1093/jac/dkn251

DOI
10.1093/jac/dkn251
Journal article

Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication.

Stöhr, W., Back, D., Dunn, D., Sabin, C., Winston, A., Gilson, R., . . . UK CHIC Study. (2008). Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication.. Antiviral therapy, 13(5), 675-685. doi:10.1177/135965350801300507

DOI
10.1177/135965350801300507
Journal article

Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes

Jones, S. P., Waitt, C., Sutton, R., Back, D. J., & Pirmohamed, M. (2008). Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes. AIDS, 22(11), 1293-1298. doi:10.1097/QAD.0b013e3283021a4f

DOI
10.1097/QAD.0b013e3283021a4f
Journal article

Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes

Jones, S. P., Waitt, C., Sutton, R., Back, D. J., & Pirmohamed, M. (2008). Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes. AIDS, 22(11), 1293-1298. doi:10.1097/qad.0b013e3283021a4f

DOI
10.1097/qad.0b013e3283021a4f
Journal article

Pharmacokinetic analysis to assess forgiveness of boosted saquinavir regimens for missed or late dosing

Dickinson, L., Boffito, M., Khoo, S. H., Schutz, M., Aarons, L. J., Pozniak, A. L., & Back, D. J. (n.d.). Pharmacokinetic analysis to assess forgiveness of boosted saquinavir regimens for missed or late dosing. Journal of Antimicrobial Chemotherapy, 62(1), 161-167. doi:10.1093/jac/dkn187

DOI
10.1093/jac/dkn187
Journal article

Pharmacokinetic analysis to assess forgiveness of boosted saquinavir regimens for missed or late dosing

Dickinson, L., Boffito, M., Khoo, S. H., Schutz, M., Aarons, L. J., Pozniak, A. L., & Back, D. J. (2008). Pharmacokinetic analysis to assess forgiveness of boosted saquinavir regimens for missed or late dosing. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 62(1), 161-167. doi:10.1093/jac/dkn187

DOI
10.1093/jac/dkn187
Journal article

Lopinavir/ritonavir pharmacokinetics in HIV/HCV-coinfected patients with or without cirrhosis.

Micheli, V., Regazzi, M., Dickinson, L., Meraviglia, P., Villani, P., Khoo, S., . . . Cargnel, A. (2008). Lopinavir/ritonavir pharmacokinetics in HIV/HCV-coinfected patients with or without cirrhosis.. Therapeutic drug monitoring, 30(3), 306-313.

Journal article

Lopinavir/ritonavir pharmacokinetics in HN/HCV-coinfected patients with or without cirrhosis

Micheli, V., Regazzi, M., Dickinson, L., Meraviglia, P., Villani, P., Khoo, S. H., . . . Cargnel, A. (2008). Lopinavir/ritonavir pharmacokinetics in HN/HCV-coinfected patients with or without cirrhosis. THERAPEUTIC DRUG MONITORING, 30(3), 306-313.

Journal article

Lopinavir/ritonavir pharmacokinetics in HN/HCV-coinfected patients with or without cirrhosis

Micheli, V., Regazzi, M., Dickinson, L., Meraviglia, P., Villani, P., Khoo, S. H., . . . Cargnel, A. (2008). Lopinavir/ritonavir pharmacokinetics in HN/HCV-coinfected patients with or without cirrhosis. THERAPEUTIC DRUG MONITORING, 30(3), 306-313. doi:10.1097/FTD.0b013e318177209e

DOI
10.1097/FTD.0b013e318177209e
Journal article

Pharmacokinetics and Safety of Saquinavir/Ritonavir and Omeprazole in HIV-infected Subjects

Singh, K., Dickinson, L., Chaikan, A., Back, D., Fletcher, C., Pozniak, A., . . . Boffito, M. (2008). Pharmacokinetics and Safety of Saquinavir/Ritonavir and Omeprazole in HIV-infected Subjects. Clinical Pharmacology &amp; Therapeutics, 83(6), 867-872. doi:10.1038/sj.clpt.6100375

DOI
10.1038/sj.clpt.6100375
Journal article

Pharmacokinetics and safety of saquinavir/ritonavir and omeprazole in HIV-infected subjects.

Singh, K., Dickinson, L., Chaikan, A., Back, D., Fletcher, C., Pozniak, A., . . . Boffito, M. (2008). Pharmacokinetics and safety of saquinavir/ritonavir and omeprazole in HIV-infected subjects.. Clinical pharmacology and therapeutics, 83(6), 867-872. doi:10.1038/sj.clpt.6100375

DOI
10.1038/sj.clpt.6100375
Journal article

Pharmacokinetics and safety of saquinavir/ritonavir and omeprazole in HIV-infected subjects.

Singh, K., Dickinson, L., Chaikan, A., Back, D., Fletcher, C., Pozniak, A., . . . Boffito, M. (2008). Pharmacokinetics and safety of saquinavir/ritonavir and omeprazole in HIV-infected subjects.. Clinical pharmacology and therapeutics, 83(6), 867-872.

Journal article

Influence of Environmental Chemicals on Drug Therapy in Humans: Studies with Contraceptive Steroids

Breckenridge, A. M., Back, D. J., Cross, K., Crawford, F., MacIver, M., L'E Orme, M., . . . Smith, E. (1980). Influence of Environmental Chemicals on Drug Therapy in Humans: Studies with Contraceptive Steroids. In Unknown Book (pp. 289-306). Wiley. doi:10.1002/9780470720592.ch16

DOI
10.1002/9780470720592.ch16
Chapter

Differences in the pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons.

Dickinson, L., Khoo, S., & Back, D. (2008). Differences in the pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons.. Current opinion in HIV and AIDS, 3(3), 296-305. doi:10.1097/coh.0b013e3282f82bf1

DOI
10.1097/coh.0b013e3282f82bf1
Journal article

Darunavir: pharmacokinetics and drug interactions.

Back, D., Sekar, V., & Hoetelmans, R. M. W. (2008). Darunavir: pharmacokinetics and drug interactions.. Antiviral therapy, 13(1), 1-13. doi:10.1177/135965350801300101

DOI
10.1177/135965350801300101
Journal article

Impact of <i>CYP2B6</i> 983T&gt;C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

Wyen, C., Hendra, H., Vogel, M., Hoffmann, C., Knechten, H., Brockmeyer, N. H., . . . Owen, A. (2008). Impact of <i>CYP2B6</i> 983T&gt;C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 61(4), 914-918. doi:10.1093/jac/dkn029

DOI
10.1093/jac/dkn029
Journal article

Response to 'communicating information about drug interactions'

Back, D. J., & Gibbons, S. E. (2008). Response to 'communicating information about drug interactions'. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 65(4), 617-618. doi:10.1111/j.1365-2125.2007.03043.x

DOI
10.1111/j.1365-2125.2007.03043.x
Journal article

Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells

Martin, P., Riley, R., Back, D. J., & Owen, A. (2008). Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. BRITISH JOURNAL OF PHARMACOLOGY, 153(4), 805-819. doi:10.1038/sj.bjp.0707601

DOI
10.1038/sj.bjp.0707601
Journal article

Differences in pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons.

Dickinson, L., Khoo, S., & Back, D. (2008). Differences in pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons.. Current Opinion in HIV & AIDS, 3, 296-305.

Journal article

Factors Influencing Efavirenz and Nevirapine Plasma Concentration: Effect of Ethnicity, Weight, and Co-Medication

Stöhr, W., Back, D., Dunn, D., Sabin, C., Winston, A., Gilson, R., . . . Khoo, S. (2008). Factors Influencing Efavirenz and Nevirapine Plasma Concentration: Effect of Ethnicity, Weight, and Co-Medication. Antiviral Therapy, 13(5), 675-685.

Journal article

Pharmacokinetics of atazanavir/ritonavir once daily and lopinavir/ritonavir twice and once daily over 72 h following drug cessation

Back, D., Else, L., Khoo, S., Boffito, M., Taylor, J., Sousa, M., . . . Moyle, G. (2008). Pharmacokinetics of atazanavir/ritonavir once daily and lopinavir/ritonavir twice and once daily over 72 h following drug cessation. ANTIVIRAL THERAPY, 13(7), 901-907.

Journal article

2007

Detection and quantification of minority HIV isolates harbouring the D30N mutation by real-time PCR amplification

Detsika, M. G., Chandler, B., Khoo, S. H., Winstanley, C., Cane, P., Back, D. J., & Owen, A. (2007). Detection and quantification of minority HIV isolates harbouring the D30N mutation by real-time PCR amplification. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 60(4), 881-884. doi:10.1093/jac/dkm281

DOI
10.1093/jac/dkm281
Journal article

A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin

Hartkoorn, R. C., Khoo, S., Back, D. J., Tjia, J. F., Waitt, C. J., Chaponda, M., . . . Ward, S. A. (2007). A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 857(1), 76-82. doi:10.1016/j.jchromb.2007.07.005

DOI
10.1016/j.jchromb.2007.07.005
Journal article

Factors impacting the expression of membrane-bound proteins in lymphocytes from HIV-positive subjects

Chandler, B., Detsika, M., Khoo, S. H., Williams, J., Back, D. J., & Owen, A. (2007). Factors impacting the expression of membrane-bound proteins in lymphocytes from HIV-positive subjects. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 60(3), 685-689. doi:10.1093/jac/dkm230

DOI
10.1093/jac/dkm230
Journal article

Stopping antiretroviral therapy.

Taylor, S., Boffito, M., Khoo, S., Smit, E., & Back, D. (2007). Stopping antiretroviral therapy.. AIDS (London, England), 21(13), 1673-1682. doi:10.1097/qad.0b013e3281c61394

DOI
10.1097/qad.0b013e3281c61394
Journal article

Abacavir plasma pharmacokinetics in the absence and presence of atazanavir/ritonavir or lopinavir/ritonavir and vice versa in HIV-infected patients.

Waters, L. J., Moyle, G., Bonora, S., D'Avolio, A., Else, L., Mandalia, S., . . . Boffito, M. (2007). Abacavir plasma pharmacokinetics in the absence and presence of atazanavir/ritonavir or lopinavir/ritonavir and vice versa in HIV-infected patients.. Antiviral therapy, 12(5), 825-830. doi:10.1177/135965350701200510

DOI
10.1177/135965350701200510
Journal article

Effect of transporter modulation on the emergence of nelfinavir resistance <i>in vitro</i>

Chandler, B., Detsika, M., Owen, A., Evans, S., Hartkoorn, R. C., Cane, P. A., . . . Khoo, S. H. (2007). Effect of transporter modulation on the emergence of nelfinavir resistance <i>in vitro</i>. ANTIVIRAL THERAPY, 12(5), 831-834. Retrieved from https://www.webofscience.com/

Journal article

Limited-sampling strategy for the prediction of boosted hard-gel saquinavir exposure at a dosage of 1000/100 mg twice daily in human immunodeficiency virus-infected individuals.

Dickinson, L., Back, D., Pozniak, A., Khoo, S., & Boffito, M. (2007). Limited-sampling strategy for the prediction of boosted hard-gel saquinavir exposure at a dosage of 1000/100 mg twice daily in human immunodeficiency virus-infected individuals.. Therapeutic drug monitoring, 29(3), 361-367.

Journal article

Limited-sampling strategy for the prediction of boosted hard-gel saquinavir exposure at a dosage of 1000/100 mg twice daily in human immunodeficiency virus-infected individuals.

Dickinson, L., Back, D., Pozniak, A., Khoo, S., & Boffito, M. (2007). Limited-sampling strategy for the prediction of boosted hard-gel saquinavir exposure at a dosage of 1000/100 mg twice daily in human immunodeficiency virus-infected individuals.. Therapeutic drug monitoring, 29(3), 361-367. doi:10.1097/ftd.0b013e3180683b25

DOI
10.1097/ftd.0b013e3180683b25
Journal article

Response to 'Nifedipine-Iopinavir/ritonavir severe interaction: a case report'

Back, D. J., & Gibbons, S. E. (2007). Response to 'Nifedipine-Iopinavir/ritonavir severe interaction: a case report'. AIDS, 21(9), 1226-1227. doi:10.1097/QAD.0b013e32811ebf8e

DOI
10.1097/QAD.0b013e32811ebf8e
Journal article

Combining resistance and pharmacology for optimum patient care

Khoo, S. H., Winston, A., & Back, D. J. (2007). Combining resistance and pharmacology for optimum patient care. CURRENT OPINION IN HIV AND AIDS, 2(3), 157-168. doi:10.1097/COH.0b013e3280f31d27

DOI
10.1097/COH.0b013e3280f31d27
Journal article

Differential drug susceptibility of intracellular and extracellular tuberculosis, and the impact of P-glycoprotein

Hartkoorn, R. C., Chandler, B., Owen, A., Ward, S. A., Squire, S. B., Back, D. J., & Khoo, S. H. (2007). Differential drug susceptibility of intracellular and extracellular tuberculosis, and the impact of P-glycoprotein. TUBERCULOSIS, 87(3), 248-255. doi:10.1016/j.tube.2006.12.001

DOI
10.1016/j.tube.2006.12.001
Journal article

Limited-sampling strategy for the prediction of boosted hard-gel saquinavir exposure at a dosage of 1000/100 mg twice daily in human immunodeficiency virus-infected individuals.

Dickinson, L., Back, D., Pozniak, A., Khoo, S., & Boffito, M. (2007). Limited-sampling strategy for the prediction of boosted hard-gel saquinavir exposure at a dosage of 1000/100 mg twice daily in human immunodeficiency virus-infected individuals.. Ther Drug Monitoring, 29(3), 361-367.

Journal article

Nifedipine-lopinavir/ritonavir severe interaction:a case report.

Back, D. J., & Gibbons, S. E. (2007). Nifedipine-lopinavir/ritonavir severe interaction:a case report.. AIDS, 21(9), 1226-1227.

Journal article

2006

Influence of atazanavir 200 mg on the intracellular and plasma pharmacokinetics of saquinavir and ritonavir 1600/100 mg administered once daily in HIV-infected patients.

Ford, J., Boffito, M., Maitland, D., Hill, A., Back, D., Khoo, S., . . . Pozniak, A. (2006). Influence of atazanavir 200 mg on the intracellular and plasma pharmacokinetics of saquinavir and ritonavir 1600/100 mg administered once daily in HIV-infected patients.. The Journal of antimicrobial chemotherapy, 58(5), 1009-1016. doi:10.1093/jac/dkl379

DOI
10.1093/jac/dkl379
Journal article

Down regulation of multidrug resistance protein-1 expression in patients with early rheumatoid arthritis exposed to methotrexate as a first disease-modifying antirheumatic drug

Hider, S. L., Owen, A., Hartkoorn, R., Khoo, S., Back, D., Silman, A. J., & Bruce, I. N. (2006). Down regulation of multidrug resistance protein-1 expression in patients with early rheumatoid arthritis exposed to methotrexate as a first disease-modifying antirheumatic drug. ANNALS OF THE RHEUMATIC DISEASES, 65(10), 1390-1393. doi:10.1136/ard.2005.049189

DOI
10.1136/ard.2005.049189
Journal article

Pharmacogenetics of HIV therapy

Owen, A., Pirmohamed, M., Khoo, S. H., & Back, D. J. (2006). Pharmacogenetics of HIV therapy. PHARMACOGENETICS AND GENOMICS, 16(10), 693-703. doi:10.1097/01.fpc.0000236338.41799.57

DOI
10.1097/01.fpc.0000236338.41799.57
Journal article

Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV Type 1-infected individuals administered different atazanavir doses.

Boffito, M., Maitland, D., Dickinson, L., Back, D., Hill, A., Fletcher, C., . . . Pozniak, A. (2006). Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV Type 1-infected individuals administered different atazanavir doses.. AIDS research and human retroviruses, 22(8), 749-756.

Journal article

Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV Type 1-infected individuals administered different atazanavir doses.

Boffito, M., Maitland, D., Dickinson, L., Back, D., Hill, A., Fletcher, C., . . . Pozniak, A. (2006). Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV Type 1-infected individuals administered different atazanavir doses.. AIDS research and human retroviruses, 22(8), 749-756. doi:10.1089/aid.2006.22.749

DOI
10.1089/aid.2006.22.749
Journal article

Effect of omeprazole on the pharmacokinetics of saquinavir-500 mg formulation with ritonavir in healthy male and female volunteers.

Winston, A., Back, D., Fletcher, C., Robinson, L., Unsworth, J., Tolowinska, I., . . . Boffito, M. (2006). Effect of omeprazole on the pharmacokinetics of saquinavir-500 mg formulation with ritonavir in healthy male and female volunteers.. AIDS (London, England), 20(10), 1401-1406. doi:10.1097/01.aids.0000233573.41597.8a

DOI
10.1097/01.aids.0000233573.41597.8a
Journal article

An update on therapeutic drug monitoring for antiretroviral drugs.

Back, D., Gibbons, S., & Khoo, S. (2006). An update on therapeutic drug monitoring for antiretroviral drugs.. Therapeutic drug monitoring, 28(3), 468-473. doi:10.1097/01.ftd.0000211825.57984.41

DOI
10.1097/01.ftd.0000211825.57984.41
Journal article

Different methods to calculate the inhibitory quotient of boosted single protease inhibitors and their association with virological response.

Winston, A., Patel, N., Back, D., Khoo, S., Bulbeck, S., Mandalia, S., . . . Boffito, M. (2006). Different methods to calculate the inhibitory quotient of boosted single protease inhibitors and their association with virological response.. Journal of acquired immune deficiency syndromes (1999), 41(5), 675-676. doi:10.1097/01.qui.0000209910.27997.d9

DOI
10.1097/01.qui.0000209910.27997.d9
Journal article

Pharmacologic optimization of protease inhibitors and nonnucleoside reverse transcriptase inhibitors (POPIN) - A randomized controlled trial of therapeutic drug monitoring and adherence support

Khoo, S. H., Lloyd, J., Dalton, M., Bonington, A., Hart, E., Gibbons, S., . . . Back, D. J. (2006). Pharmacologic optimization of protease inhibitors and nonnucleoside reverse transcriptase inhibitors (POPIN) - A randomized controlled trial of therapeutic drug monitoring and adherence support. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 41(4), 461-467. doi:10.1097/01.qai.0000218345.65434.21

DOI
10.1097/01.qai.0000218345.65434.21
Journal article

Population pharmacokinetics of efavirenz in an unselected cohort of HIV-1-infected individuals

Back, D. J., Owen, A., & Khoo, S. H. (2006). Population pharmacokinetics of efavirenz in an unselected cohort of HIV-1-infected individuals. CLINICAL PHARMACOKINETICS, 45(2), 213-214. doi:10.2165/00003088-200645020-00006

DOI
10.2165/00003088-200645020-00006
Journal article

Drug-drug interactions that matter.

Back, D. J. (2006). Drug-drug interactions that matter.. Topics in HIV medicine : a publication of the International AIDS Society, USA, 14(2), 88-92.

Journal article

Effect of omeprazole on the pharmacokinetics of saquinavir-500 mg formulation with ritonavir in healthy male and female volunteers

Winston, A., Back, D., Fletcher, C., Robinson, L., Unsworth, J., Tolowinska, I., . . . Boffito, M. (2006). Effect of omeprazole on the pharmacokinetics of saquinavir-500 mg formulation with ritonavir in healthy male and female volunteers. AIDS, 20(10), 401-406.

Journal article

Pharmacokinetics of reverse transcriptase inhibitors

Hoggard, P., Kewn, S., Khoo, S., & Back, D. (2006). Pharmacokinetics of reverse transcriptase inhibitors. In G. Skowron, & R. Ogden (Eds.), Reverse Transcriptase Inhibitors in HIV/AIDS Therapy (pp. xxx). Totowa, New Jersey: Humana Press.

Chapter

Pharmacological Optimization of PIs and NNRTIs (POPIN)- a randomised controlled trial of therapeutic drug monitoring and adherence support.

Khoo, S. H., Lloyd, J., Dalton, M., Bonington, A., Hart, E., Gibbons, S., . . . Back, D. J. (2006). Pharmacological Optimization of PIs and NNRTIs (POPIN)- a randomised controlled trial of therapeutic drug monitoring and adherence support.. J Acquir Immune Defic Syndr, 41(4), 461-467.

Journal article

2005

Simultaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

Dickinson, L., Robinson, L., Tjia, J., Khoo, S., & Back, D. (2005). Simultaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir in human plasma by high-performance liquid chromatography-tandem mass spectrometry.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 829(1-2), 82-90.

Journal article

Simultaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

Dickinson, L., Robinson, L., Tjia, J., Khoo, S., & Back, D. (2005). Simultaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir in human plasma by high-performance liquid chromatography-tandem mass spectrometry.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 829(1-2), 82-90. doi:10.1016/j.jchromb.2005.09.032

DOI
10.1016/j.jchromb.2005.09.032
Journal article

Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudineand zidovudine-containing regimens

Jones, S. P., Qazi, N., Morelese, J., Lebrecht, D., Sutinen, J., Yki-Járvinen, H., . . . Moyle, G. J. (2005). Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudineand zidovudine-containing regimens. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 40(5), 565-572. doi:10.1097/01.qai.0000187443.30838.3e

DOI
10.1097/01.qai.0000187443.30838.3e
Journal article

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP

Janneh, O., Owen, A., Chandler, B., Hartkoorn, R. C., Hart, C. A., Bray, P. G., . . . Khoo, S. H. (2005). Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP. AIDS, 19(18), 2097-2102. doi:10.1097/01.aids.0000194793.36175.40

DOI
10.1097/01.aids.0000194793.36175.40
Journal article

Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study.

Rodriguez-Torres, M., Torriani, F. J., Soriano, V., Borucki, M. J., Lissen, E., Sulkowski, M., . . . Back, D. (2005). Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study.. Antimicrobial agents and chemotherapy, 49(10), 3997-4008. doi:10.1128/aac.49.10.3997-4008.2005

DOI
10.1128/aac.49.10.3997-4008.2005
Journal article

Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals

Almond, L. M., Hoggard, P. G., Edirisinghe, D., Khoo, S. H., & Back, D. J. (2005). Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 56(4), 738-744. doi:10.1093/jac/dki308

DOI
10.1093/jac/dki308
Journal article

In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine

Owen, A., Janneh, O., Hartkoorn, R. C., Chandler, B., Bray, P. G., Martin, P., . . . Back, D. J. (2005). In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 314(3), 1202-1209. doi:10.1124/jpet.105.086272

DOI
10.1124/jpet.105.086272
Journal article

In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine.

Owen, A., Janneh, O., Hartkoorn, R. C., Chandler, B., Bray, P. G., Martin, P., . . . Back, D. J. (2005). In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine.. The Journal of pharmacology and experimental therapeutics, 314(3), 1202-1209. doi:10.1124/jpet.105.086272

DOI
10.1124/jpet.105.086272
Journal article

Altered adipokine response in murine 3T3-F442A adipocytes treated with protease inhibitors and nucleoside reverse transcriptase inhibitors

Jones, S. P., Janneh, O., Back, D. J., & Pirmohamed, M. (2005). Altered adipokine response in murine 3T3-F442A adipocytes treated with protease inhibitors and nucleoside reverse transcriptase inhibitors. ANTIVIRAL THERAPY, 10(2), 207-213. Retrieved from https://www.webofscience.com/

Journal article

Current status and future prospects of therapeutic drug monitoring and applied clinical pharmacology in antiretroviral therapy.

Boffito, M., Acosta, E., Burger, D., Fletcher, C. V., Flexner, C., Garaffo, R., . . . Back, D. (2005). Current status and future prospects of therapeutic drug monitoring and applied clinical pharmacology in antiretroviral therapy.. Antiviral therapy, 10(3), 375-392. doi:10.1177/135965350501000307

DOI
10.1177/135965350501000307
Journal article

Therapeutic drug monitoring and drug-drug interactions involving antiretroviral drugs.

Boffito, M., Acosta, E., Burger, D., Fletcher, C. V., Flexner, C., Garaffo, R., . . . Back, D. (2005). Therapeutic drug monitoring and drug-drug interactions involving antiretroviral drugs.. Antiviral therapy, 10(4), 469-477. doi:10.1177/135965350501000413

DOI
10.1177/135965350501000413
Journal article

Intracellular and plasma pharmacokinetics of nevirapine in human immunodeficiency virus-infected individuals

Almond, L. M., Edirisinghe, D., Dalton, M., Bonington, A., Back, D. J., & Khoo, S. H. (2005). Intracellular and plasma pharmacokinetics of nevirapine in human immunodeficiency virus-infected individuals. CLINICAL PHARMACOLOGY & THERAPEUTICS, 78(2), 132-142. doi:10.1016/j.clpt.2005.04.004

DOI
10.1016/j.clpt.2005.04.004
Journal article

The pharmacology of antiretroviral nucleoside and nucleotide reverse transcriptase inhibitors - Implications for once-daily dosing

Back, D. J., Burger, D. M., Flexner, C. W., & Gerber, J. G. (2005). The pharmacology of antiretroviral nucleoside and nucleotide reverse transcriptase inhibitors - Implications for once-daily dosing. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 39, S1-S23. doi:10.1097/01.qai.0000168882.67942.3f

DOI
10.1097/01.qai.0000168882.67942.3f
Journal article

The potential for interactions between antimalarial and antiretroviral drugs

Khoo, S., Back, D., & Winstanley, P. (2005). The potential for interactions between antimalarial and antiretroviral drugs. AIDS, 19(10), 995-1005.

Journal article

The potential for interactions between antimalarial and antiretroviral drugs.

Khoo, S., Back, D., & Winstanley, P. (2005). The potential for interactions between antimalarial and antiretroviral drugs.. AIDS (London, England), 19(10), 995-1005. doi:10.1097/01.aids.0000174445.40379.e0

DOI
10.1097/01.aids.0000174445.40379.e0
Journal article

The implications of P-glycoprotein in HIV: friend or foe?

Owen, A., Chandler, B., & Back, D. J. (2005). The implications of P-glycoprotein in HIV: friend or foe?. FUNDAMENTAL & CLINICAL PHARMACOLOGY, 19(3), 283-296. doi:10.1111/j.1472-8206.2005.00324.x

DOI
10.1111/j.1472-8206.2005.00324.x
Journal article

Boosted saquinavir hard gel formulation exposure in HIV-infected subjects: ritonavir 100 mg once daily versus twice daily.

Boffito, M., Maitland, D., Dickinson, L., Back, D., Hill, A., Fletcher, C., . . . Pozniak, A. (2005). Boosted saquinavir hard gel formulation exposure in HIV-infected subjects: ritonavir 100 mg once daily versus twice daily.. The Journal of antimicrobial chemotherapy, 55(4), 542-545. doi:10.1093/jac/dki043

DOI
10.1093/jac/dki043
Journal article

Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine- and zidovudine-containing regimens

Jones, S. P., Qazi, N., Morelese, J., Lebrecht, D., Sutinen, J., Yki-Jarvinen, H., . . . Moyle, G. J. (2005). Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine- and zidovudine-containing regimens. Journal of Acquired Immune Deficiency Syndromes, 40, 562-572.

Journal article

Drug efflux transporters in rheumatoid arthritis: comment on the article by Kremer.

Hider, S. L., Hoggard, P., Khoo, S., Back, D., & Bruce, I. N. (2005). Drug efflux transporters in rheumatoid arthritis: comment on the article by Kremer.. Arthritis and rheumatism, 52(2), 670. doi:10.1002/art.20770

DOI
10.1002/art.20770
Journal article

In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine

Owen, A., Janneh, O., Hartkoorn, R. C., Chandler, B., Bray, P. G., Martin, P., . . . Back, D. J. (2005). In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine. J Pharmacol Exp Ther, 314(3), 1202-1209.

Journal article

Intracellular accumulation of human immunodeficiency virus protease inhibitors

Boffito, M., Acosta, E., Burger, D., Fletcher, C. V., Flexner, C., Garaffo, R., . . . Back, D. (2005). Intracellular accumulation of human immunodeficiency virus protease inhibitors. Antiviral Therapy, 10, 3228-3235. doi:10.1128/AAC.46.10.3228-3235.2002

DOI
10.1128/AAC.46.10.3228-3235.2002
Journal article

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP

Janneh, O., Owen, A., Chandler, B., Hartkoorn, R. C., Hart, C. A., Bray, P. G., . . . Khoo, S. (2005). Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP. AIDS, 19(18), 2097-2102.

Journal article

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP.

Janneh, O., Owen, A., Chandler, B., Hartkoorn, R. C., Hart, C. A., Bray, P. G., . . . Khoo, S. H. (2005). Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP.. AIDS, 19(18), 2097-2102. Retrieved from http://gateway.ut.ovid.com/

Journal article

Pharmacokinetics of saquinavir hard gel/ritonavir (1000/100 mg twice daily) when administered with tenofovir diproxil fumarate in HIV-1-infected subjects.

Boffito, M., Back, D., Stainsby-Tron, M., Hill, A., Di Perri, G., Moyle, G., . . . Pozniak, A. (2005). Pharmacokinetics of saquinavir hard gel/ritonavir (1000/100 mg twice daily) when administered with tenofovir diproxil fumarate in HIV-1-infected subjects.. British journal of clinical pharmacology, 59(1), 38-42. doi:10.1111/j.1365-2125.2004.02240.x

DOI
10.1111/j.1365-2125.2004.02240.x
Journal article

Similtaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir in human plasma by high performance liquid chromatography-tandem mass spectrometry.

Dickinson, L., Robinson, L., Tjia, J., Khoo, S. H., & Back, D. (2005). Similtaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir in human plasma by high performance liquid chromatography-tandem mass spectrometry.. J Chromatogr B, 831, 258-266.

Journal article

2004

A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients

Perucca, E., Hedges, A., Makki, K. A., Ruprah, M., Wilson, J. F., Richens, A., & Back, D. (2004). A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. British Journal of Clinical Pharmacology, 58(7 SPEC. ISS.).

Journal article

Lipodystrophy in patients with HIV-1 infection:: effect of stopping protease inhibitors on TNF-α and TNF-receptor levels, and on metabolic parameters

Maher, B., Lloyd, J., Wilkins, E. G. L., Fraser, W. D., Back, D., Park, B. K., & Pirmohamed, M. (2004). Lipodystrophy in patients with HIV-1 infection:: effect of stopping protease inhibitors on TNF-α and TNF-receptor levels, and on metabolic parameters. ANTIVIRAL THERAPY, 9(6), 879-887. Retrieved from https://www.webofscience.com/

Journal article

Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4

Owen, A., Chandler, B., Bray, P. G., Ward, S. A., Hart, C. A., Back, D. J., & Khoo, S. H. (2004). Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4. JOURNAL OF VIROLOGY, 78(21), 12022-12029. doi:10.1128/JVI.78.21.12022-12029.2004

DOI
10.1128/JVI.78.21.12022-12029.2004
Journal article

Steady-State Pharmacokinetics of Saquinavir Hard-Gel/Ritonavir/Fosamprenavir in HIV-1???Infected Patients

Boffito, M., Dickinson, L., Hill, A., Back, D., Moyle, G., Nelson, M., . . . Pozniak, A. (2004). Steady-State Pharmacokinetics of Saquinavir Hard-Gel/Ritonavir/Fosamprenavir in HIV-1???Infected Patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 37(3), 1376-1384. doi:10.1097/01.qai.0000136060.65716.1a

DOI
10.1097/01.qai.0000136060.65716.1a
Journal article

Steady-State pharmacokinetics of saquinavir hard-gel/ritonavir/fosamprenavir in HIV-1-infected patients.

Boffito, M., Dickinson, L., Hill, A., Back, D., Moyle, G., Nelson, M., . . . Pozniak, A. (2004). Steady-State pharmacokinetics of saquinavir hard-gel/ritonavir/fosamprenavir in HIV-1-infected patients.. Journal of acquired immune deficiency syndromes (1999), 37(3), 1376-1384. doi:10.1097/01.qai.0000136060.65716.1a

DOI
10.1097/01.qai.0000136060.65716.1a
Journal article

Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and on intracellular nucleoside triphosphate pools

Sankatsing, S. U. C., Hoggard, P. G., Huitema, A. D. R., Sparidans, R. W., Kewn, S., Crommentuyn, K. M. L., . . . Prins, J. M. (2004). Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and on intracellular nucleoside triphosphate pools. CLINICAL PHARMACOKINETICS, 43(12), 823-832. doi:10.2165/00003088-200443120-00004

DOI
10.2165/00003088-200443120-00004
Journal article

Expression of pregnane-X-receptor transcript in peripheral blood mononuclear cells and correlation with MDR1 mRNA

Owen, A., Chandler, B., Back, D. J., & Khoo, S. H. (2004). Expression of pregnane-X-receptor transcript in peripheral blood mononuclear cells and correlation with MDR1 mRNA. ANTIVIRAL THERAPY, 9(5), 819-821. Retrieved from https://www.webofscience.com/

Journal article

Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen

Isaac, A., Taylor, S., Cane, P., Smit, E., Gihbons, S. E., White, D. J., . . . Back, D. J. (2004). Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 54(2), 498-502. doi:10.1093/jac/dkh357

DOI
10.1093/jac/dkh357
Journal article

Intracellular and plasma pharmacokinetics of saquinavir-ritonavir, administered at 1,600/100 milligrams once daily in human immunodeficiency virus-infected patients.

Ford, J., Boffito, M., Wildfire, A., Hill, A., Back, D., Khoo, S., . . . Pozniak, A. (2004). Intracellular and plasma pharmacokinetics of saquinavir-ritonavir, administered at 1,600/100 milligrams once daily in human immunodeficiency virus-infected patients.. Antimicrobial agents and chemotherapy, 48(7), 2388-2393. doi:10.1128/aac.48.7.2388-2393.2004

DOI
10.1128/aac.48.7.2388-2393.2004
Journal article

The relationship between nevirapine plasma concentrations and abnormal liver function tests

Almond, L. M., Boffito, M., Hoggard, P. G., Bonora, S., Raiteri, R., Reynolds, H. E., . . . Di Perri, G. (2004). The relationship between nevirapine plasma concentrations and abnormal liver function tests. AIDS RESEARCH AND HUMAN RETROVIRUSES, 20(7), 716-722. doi:10.1089/0889222041524670

DOI
10.1089/0889222041524670
Journal article

Pharmacokinetics of once-daily saquinavir/ritonavir in HIV-infected subjects: comparison with the standard twice-daily regimen.

Boffito, M., Dickinson, L., Hill, A., Back, D., Moyle, G., Nelson, M., . . . Pozniak, A. (2004). Pharmacokinetics of once-daily saquinavir/ritonavir in HIV-infected subjects: comparison with the standard twice-daily regimen.. Antiviral therapy, 9(3), 423-429.

Journal article

Pharmacokinetics of once-daily saquinavir/ritonavir in HIV-infected subjects: comparison with the standard twice-daily regimen.

Boffito, M., Dickinson, L., Hill, A., Back, D., Moyle, G., Nelson, M., . . . Pozniak, A. (2004). Pharmacokinetics of once-daily saquinavir/ritonavir in HIV-infected subjects: comparison with the standard twice-daily regimen.. Antiviral therapy, 9(3), 423-429. doi:10.1177/135965350400900315

DOI
10.1177/135965350400900315
Journal article

Clinical implications of stopping nevirapine-based antiretroviral therapy: relative pharmacokinetics and avoidance of drug resistance.

Mackie, N. E., Fidler, S., Tamm, N., Clarke, J. R., Back, D., Weber, J. N., & Taylor, G. P. (2004). Clinical implications of stopping nevirapine-based antiretroviral therapy: relative pharmacokinetics and avoidance of drug resistance.. HIV medicine, 5(3), 180-184. doi:10.1111/j.1468-1293.2004.00208.x

DOI
10.1111/j.1468-1293.2004.00208.x
Journal article

Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals?

Winston, A., Pozniak, A., Smith, N., Fletcher, C., Mandalia, S., Parmar, D., . . . Nelson, M. (2004). Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals?. AIDS (London, England), 18(3), 572-574. doi:10.1097/00002030-200402200-00029

DOI
10.1097/00002030-200402200-00029
Journal article

Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients.

Hennessy, M., Clarke, S., Spiers, J. P., Kelleher, D., Mulcahy, F., Hoggard, P., . . . Barry, M. (2004). Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients.. Antiviral therapy, 9(1), 115-122. doi:10.1177/135965350400900103

DOI
10.1177/135965350400900103
Journal article

Intracellular and plasma pharmacokinetics of nelfinavir and M8 in HIV-infected patients: relationship with P-glycoprotein expression

Ford, J., Cornforth, D., Hoggard, P. G., Cuthbertson, Z., Meaden, E. R., Williams, I., . . . Khoo, S. H. (2004). Intracellular and plasma pharmacokinetics of nelfinavir and M8 in HIV-infected patients: relationship with P-glycoprotein expression. ANTIVIRAL THERAPY, 9(1), 77-84. Retrieved from https://www.webofscience.com/

Journal article

Lopinavir protein binding in vivo through the 12-hour dosing interval

Boffito, M., Hoggard, P. G., Lindup, W. E., Bonora, S., Sinicco, A., Khoo, S. H., . . . Back, D. J. (2004). Lopinavir protein binding in vivo through the 12-hour dosing interval. THERAPEUTIC DRUG MONITORING, 26(1), 35-39. doi:10.1097/00007691-200402000-00008

DOI
10.1097/00007691-200402000-00008
Journal article

Expression of pregnane-X-receptor transcript in peripheral blood mononuclear cells and correlation with MDR1 mRNA.

Owen, A., Chandler, B., Back, D. J., & Khoo, S. H. (2004). Expression of pregnane-X-receptor transcript in peripheral blood mononuclear cells and correlation with MDR1 mRNA.. Antiviral Therapy, 9(5), 819-821.

Journal article

Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4

Owen, A., Chandler, B., Bray, P. G., Ward, S. A., Hart, C. A., Back, D., & Khoo, S. (2004). Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4. J Virol, 78(21), 12022-12029.

Journal article

Intracellular and plasma pharmacokinetics of nelfinavir and M8 in HIV-infected patients: relationship with P-glycoprotein expression.

Ford, J., Cornforth, D., Hoggard, P. G., Cutherbertson, Z., Meaden, E. R., Williams, I., . . . Khoo, S. H. (2004). Intracellular and plasma pharmacokinetics of nelfinavir and M8 in HIV-infected patients: relationship with P-glycoprotein expression.. Antiviral Therapy, 9(1), 77-84.

Journal article

Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen

Isaac, A., Taylor, S., Cane, P., Smit, E., Gibbons, S., White, D. J., . . . Back, D. (2004). Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen. J Antimicrob Chemother, 54(2), 498-502.

Journal article

Pharmacokinetics of once-daily saquinavir/ritonavir in HIV-infected subjects: comparison with the standard twice-daily regimen.

Boffito, M., Dicckinson, L., Hill, A., Back, D., Moyle, G., Nelson, M., . . . Pozniak, A. (2004). Pharmacokinetics of once-daily saquinavir/ritonavir in HIV-infected subjects: comparison with the standard twice-daily regimen.. Antiviral Therapy, 9(3), 423-429.

Journal article

Pharmacology update: drug-drug interactions and ethnic and sex differences.

Back, D. J., Dickinson, L., Canta, F., & Khoo, S. (2004). Pharmacology update: drug-drug interactions and ethnic and sex differences.. HIV/AIDS Annual Update 2004.

Journal article

Steady-state pharmacokinetics of saquinavair hard-gel/ritonavir/fosamprenavir in HIV-1-infected patients.

Boffito, M., Dickinson, L., Hill, A., Back, D., Moyle, G., Nelson, M., . . . Pozniak, A. (2004). Steady-state pharmacokinetics of saquinavair hard-gel/ritonavir/fosamprenavir in HIV-1-infected patients.. Journal of Acquired Immune Deficiency Syndrome., 37(3), 1376-1384.

Journal article

The intracellular pharmacology of antiretroviral protease inhibitors

Ford, J., Khoo, S. H., & Back, D. J. (2004). The intracellular pharmacology of antiretroviral protease inhibitors. Journal of Antimicrobial Chemotherapy.

Journal article

2003

Treating Advanced HIV Infection

Boffito, M., Bonora, S., Sinicco, A., Raiteri, R., Milia, M. G., Khoo, S. H., . . . Di Perri, G. (2003). Treating Advanced HIV Infection. JAIDS Journal of Acquired Immune Deficiency Syndromes, 34(3), 344-345. doi:10.1097/00126334-200311010-00014

DOI
10.1097/00126334-200311010-00014
Journal article

Treating advanced HIV infection

Boffito, M., Bonora, S., Sinicco, A., Raiteri, R., Milia, M. G., Khoo, S. H., . . . Di Perri, G. (2003). Treating advanced HIV infection. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 34(3), 344-345. doi:10.1097/00126334-200311010-00014

DOI
10.1097/00126334-200311010-00014
Journal article

Expression of P-glycoprotein, multidrug-resistance proteins 1 and 2 in CEM, CEM<sub>VBL</sub>, CEM<sub>E1000</sub>, MDCKII<sub>MRP1</sub> and MDCKII<sub>MRP2</sub> cell lines

Owen, A., Hartkoorn, R. C., Khoo, S., & Back, D. (2003). Expression of P-glycoprotein, multidrug-resistance proteins 1 and 2 in CEM, CEM<sub>VBL</sub>, CEM<sub>E1000</sub>, MDCKII<sub>MRP1</sub> and MDCKII<sub>MRP2</sub> cell lines. AIDS, 17(15), 2276-2278. doi:10.1097/00002030-200310170-00024

DOI
10.1097/00002030-200310170-00024
Journal article

Intracellular disposition and metabolic effects of zidovudine, stavudine and four protease inhibitors in cultured adipocytes

Janneh, O., Haggard, P., Tjia, J. F., Jones, S. P., Khoo, S. H., Maher, B., . . . Pirmohamed, M. (2003). Intracellular disposition and metabolic effects of zidovudine, stavudine and four protease inhibitors in cultured adipocytes. ANTIVIRAL THERAPY, 8(5), 417-426. Retrieved from https://www.webofscience.com/

Journal article

Ketoconazole and lopinavir/ritonavir coadministration: Boosting beyond boosting

Boffito, M., Bonora, S., Sales, P., Dal Conte, I., Sinicco, A., Hoggard, P. G., . . . Di Perri, G. (2003). Ketoconazole and lopinavir/ritonavir coadministration: Boosting beyond boosting. AIDS RESEARCH AND HUMAN RETROVIRUSES, 19(10), 941-942. doi:10.1089/088922203322493148

DOI
10.1089/088922203322493148
Journal article

Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression

Ford, J., Meaden, E. R., Hoggard, P. G., Dalton, M., Newton, P., Williams, I., . . . Back, D. J. (2003). Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 52(3), 354-358. doi:10.1093/jac/dkg381

DOI
10.1093/jac/dkg381
Journal article

Pharmacokinetic drug interactions with nevirapine.

Back, D., Gibbons, S., & Khoo, S. (2003). Pharmacokinetic drug interactions with nevirapine.. Journal of acquired immune deficiency syndromes (1999), 34 Suppl 1, S8-14. doi:10.1097/00126334-200309011-00003

DOI
10.1097/00126334-200309011-00003
Journal article

Protein binding in antiretroviral therapies

Boffito, M., Back, D. J., Blaschke, T. F., Rowland, M., Bertz, R. J., Gerber, J. G., & Miller, V. (2003). Protein binding in antiretroviral therapies. AIDS RESEARCH AND HUMAN RETROVIRUSES, 19(9), 825-835. doi:10.1089/088922203769232629

DOI
10.1089/088922203769232629
Journal article

The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on P-glycoprotein expression in peripheral blood mononuclear cells in vitro

Chandler, B., Almond, L., Ford, J., Owen, A., Hoggard, P., Khoo, S., & Back, D. (2003). The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on P-glycoprotein expression in peripheral blood mononuclear cells in vitro. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 33(5), 551-556. doi:10.1097/00126334-200308150-00001

DOI
10.1097/00126334-200308150-00001
Journal article

A longitudinal study of maternal dose response to low molecular weight heparin in pregnancy

Sephton, V., Farquharson, R. G., Topping, J., Quenby, S. M., Cowan, C., Back, D. J., & Toh, C. H. (2003). A longitudinal study of maternal dose response to low molecular weight heparin in pregnancy. OBSTETRICS AND GYNECOLOGY, 101(6), 1307-1311. doi:10.1016/S0029-7844(03)00340-5

DOI
10.1016/S0029-7844(03)00340-5
Journal article

Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics.

Hennessy, M., Clarke, S., Spiers, J. P., Mulcahy, F., Kelleher, D., Meadon, E., . . . Barry, M. (2003). Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics.. Antiviral therapy, 8(3), 191-198.

Journal article

Intra-individual variability in lopinavir plasma trough concentrations supports therapeutic drug monitoring

Boffito, M., Back, D. J., Hoggard, P. G., Caci, A., Bonora, S., Raiteri, R., . . . Di Perri, G. (2003). Intra-individual variability in lopinavir plasma trough concentrations supports therapeutic drug monitoring. AIDS, 17(7), 1107-1108. doi:10.1097/00002030-200305020-00029

DOI
10.1097/00002030-200305020-00029
Journal article

The role of clinical pharmacology in optimizing antiretroviral therapy

Back, D. J., & Khoo, S. H. (2003). The role of clinical pharmacology in optimizing antiretroviral therapy. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 55(5), 473-476. doi:10.1046/j.1365-2125.2003.01843.x

DOI
10.1046/j.1365-2125.2003.01843.x
Journal article

A simplified approach to determining P-glycoprotein expression in peripheral blood mononuclear cell subsets

Ford, J., Hoggard, P. G., Owen, A., Khoo, S. H., & Back, D. J. (2003). A simplified approach to determining P-glycoprotein expression in peripheral blood mononuclear cell subsets. JOURNAL OF IMMUNOLOGICAL METHODS, 274(1-2), 129-137. doi:10.1016/S0022-1759(02)00509-4

DOI
10.1016/S0022-1759(02)00509-4
Journal article

Differential expression of human immunodeficiency virus coreceptors, by CEM, CEM<sub>VBL</sub>, and CEM E<sub>1000</sub> cells

Owen, A., Chandler, B., Ford, J., Khoo, S., & Back, D. (2003). Differential expression of human immunodeficiency virus coreceptors, by CEM, CEM<sub>VBL</sub>, and CEM E<sub>1000</sub> cells. JOURNAL OF INFECTIOUS DISEASES, 187(5), 874-875. doi:10.1086/367902

DOI
10.1086/367902
Journal article

Lopinavir/ritonavir absorption in a gastrectomized patient.

Boffito, M., Lucchini, A., Maiello, A., Dal Conte, I., Hoggard, P. G., Back, D. J., & Di Perri, G. (2003). Lopinavir/ritonavir absorption in a gastrectomized patient.. AIDS (London, England), 17(1), 136-137. doi:10.1097/00002030-200301030-00023

DOI
10.1097/00002030-200301030-00023
Journal article

Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients

Kewn, S., Wang, L. H., Hoggard, P. G., Rousseau, F., Hart, R., MacNeela, J. P., . . . Back, D. J. (2003). Enzymatic assay for measurement of intracellular DXG triphosphate concentrations in peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected patients. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 47(1), 255-261. doi:10.1128/AAC.47.1.255-261.2003

DOI
10.1128/AAC.47.1.255-261.2003
Journal article

Intracellular disposition and metabolic effects of zidovudine, stavudine and four protease inhibitors in cultured adipocytes

Janneh, O., Hoggard, P. G., Tjia, J. F., Jones, S. P., Khoo, S. H., Maher, B., . . . Pirmohamed, M. (2003). Intracellular disposition and metabolic effects of zidovudine, stavudine and four protease inhibitors in cultured adipocytes. Antivir Ther, 8(5), 417-426. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/14640389

Journal article

Intracellular disposition and metabolic effects of zidovudine, stavudine, and four protease inhibitors in cultured adipocytes

Janneh, O., Hoggard, P. G., Tjia, J. F., Jones, S. P., Khoo, S. H., Maher, B., . . . Pirmohamed, M. (2003). Intracellular disposition and metabolic effects of zidovudine, stavudine, and four protease inhibitors in cultured adipocytes. Antiviral Therapy, 8(5), 417-426.

Journal article

Intracellular indinavir pharmacokinetics in HIV-infected patients; comparison with plasma pharmacokinetics.

Hennessy, M., Clarke, S., Spiers, J. P., Mulcahy, F., Kelleher, D., Meaden, E., . . . Barry, M. (2003). Intracellular indinavir pharmacokinetics in HIV-infected patients; comparison with plasma pharmacokinetics.. Antiviral Therapy, 8, 191-198.

Journal article

Lopinavir/ritonavir absorption in a gastrectomized patient

Boffito, M., Lucchini, A., Maiello, A., Dal Conte, I., Hoggard, P. G., Back, D. J., & Di Perri, G. (2003). Lopinavir/ritonavir absorption in a gastrectomized patient. AIDS, 17(1), 136-137. doi:10.1097/00002030-200301030-00023

DOI
10.1097/00002030-200301030-00023
Journal article

Pharmacokinetic drug interactions with nevirapine

Back, D., Gibbons, S., & Khoo, S. (2003). Pharmacokinetic drug interactions with nevirapine. J Acquir Immune Defic Syndr, 34 Sup, S8-S14. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/14562853

Journal article

The relationship between nevirapine plasma concentrations and abnormal liver function tests.

Almond, L. M., Boffito, M., Hoggard, P. G., Bonora, S., Raiteri, R., Reynolds, H. E., . . . diPerri, G. (2003). The relationship between nevirapine plasma concentrations and abnormal liver function tests.. AIDS Research and Human Retroviruses, 20, 716-720.

Journal article

2002

Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea

Hoggard, P. G., Kewn, S., Maherbe, A., Wood, R., Almond, L. M., Sales, S. D., . . . Khoo, S. H. (2002). Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea. AIDS, 16(18), 2439-2446. doi:10.1097/00002030-200212060-00009

DOI
10.1097/00002030-200212060-00009
Journal article

Pharmacokinetics of saquinavir co-administered with cimetidine

Boffito, M., Carriero, P., Trentini, L., Raiteri, R., Bonora, S., Sinicco, A., . . . Di Perri, G. (2002). Pharmacokinetics of saquinavir co-administered with cimetidine. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 50(6), 1081-1084. doi:10.1093/jac/dkf232

DOI
10.1093/jac/dkf232
Journal article

Lopinavir measurement in pleural effusion in a human immunodeficiency virus type 1-infected patient with Kaposi's sarcoma

Boffito, M., Hoggard, P. G., Back, D. J., Bonora, S., Maiello, S., Maiello, A., . . . Di Perri, G. (2002). Lopinavir measurement in pleural effusion in a human immunodeficiency virus type 1-infected patient with Kaposi's sarcoma. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 46(11), 3684-3685. doi:10.1128/AAC.46.11.3684-3685.2002

DOI
10.1128/AAC.46.11.3684-3685.2002
Journal article

Clinical use of lopinavir/ritonavir in a salvage therapy setting: pharmacokinetics and pharmacodynamics

Boffito, M., Arnaudo, I., Raiteri, R., Bonora, S., Sinicco, A., Di Garbo, A., . . . Di Perri, G. (2002). Clinical use of lopinavir/ritonavir in a salvage therapy setting: pharmacokinetics and pharmacodynamics. AIDS, 16(15), 2081-2083. doi:10.1097/00002030-200210180-00015

DOI
10.1097/00002030-200210180-00015
Journal article

Intracellular accumulation of human immunodeficiency virus protease inhibitors

Khoo, S. H., Hoggard, P. G., Williams, I., Meaden, E. R., Newton, P., Wilkins, E. G., . . . Back, D. J. (2002). Intracellular accumulation of human immunodeficiency virus protease inhibitors. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 46(10), 3228-3235. doi:10.1128/AAC.46.10.3228-3235.2002

DOI
10.1128/AAC.46.10.3228-3235.2002
Journal article

P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals

Meaden, E. R., Hoggard, P. G., Newton, P., Tjia, J. F., Aldam, D., Cornforth, D., . . . Khoo, S. H. (2002). P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 50(4), 583-588. doi:10.1093/jac/dkf161

DOI
10.1093/jac/dkf161
Journal article

Simultaneous determination of rifampicin and efavirenz in plasma.

Boffito, M., Tija, J., Reynolds, H. E., Hoggard, P. G., Bonora, S., Di Perri, G., & Back, D. J. (2002). Simultaneous determination of rifampicin and efavirenz in plasma.. Therapeutic drug monitoring, 24(5), 670-674. doi:10.1097/00007691-200210000-00015

DOI
10.1097/00007691-200210000-00015
Journal article

The unbound percentage of saquinavir and indinavir remains constant throughout the dosing interval in HIV positive subjects

Boffito, M., Hoggard, P. G., Reynolds, H. E., Bonora, S., Meaden, E. R., Sinicco, A., . . . Back, D. J. (2002). The unbound percentage of saquinavir and indinavir remains constant throughout the dosing interval in HIV positive subjects. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 54(3), 262-268. doi:10.1046/j.1365-2125.2002.01663.x

DOI
10.1046/j.1365-2125.2002.01663.x
Journal article

The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA.

Margolis, D. M., Kewn, S., Coull, J. J., Ylisastigui, L., Turner, D., Wise, H., . . . Back, D. (2002). The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA.. Journal of acquired immune deficiency syndromes (1999), 31(1), 45-49. doi:10.1097/00126334-200209010-00006

DOI
10.1097/00126334-200209010-00006
Journal article

Pharmacokinetic evaluation of indinavir and indinavir/ritonavir-containing antiretroviral regimens in a clinical setting

Boffito, M., Bonora, S., Raiteri, R., Reynolds, H. E., Hoggard, P. G., Sinicco, A., . . . Di Perri, G. (2002). Pharmacokinetic evaluation of indinavir and indinavir/ritonavir-containing antiretroviral regimens in a clinical setting. THERAPEUTIC DRUG MONITORING, 24(4), 574-576. doi:10.1097/00007691-200208000-00021

DOI
10.1097/00007691-200208000-00021
Journal article

Therapeutic drug monitoring.

Back, D., Khoo, S., & Gibbons, S. (2002). Therapeutic drug monitoring.. Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002), 1(3), 84-85. doi:10.1177/154510970200100301

DOI
10.1177/154510970200100301
Journal article

α<sub>1</sub>-acid glycoprotein levels in human immunodeficiency virus-infected subjects on antiretroviral regimens

Boffito, M., Sciole, K., Raiteri, R., Bonora, S., Hoggard, P. G., Back, D. J., & Di Perri, G. (2002). α<sub>1</sub>-acid glycoprotein levels in human immunodeficiency virus-infected subjects on antiretroviral regimens. DRUG METABOLISM AND DISPOSITION, 30(7), 859-860. doi:10.1124/dmd.30.7.859

DOI
10.1124/dmd.30.7.859
Journal article

Multidrug resistance and response to antiretroviral treatment.

Dietrich, C. G., Geier, A., Matern, S., & Gartung, C. (2002). Multidrug resistance and response to antiretroviral treatment.. Lancet (London, England), 359(9323), 2114. doi:10.1016/s0140-6736(02)08921-3

DOI
10.1016/s0140-6736(02)08921-3
Journal article

Intracellular carbovir triphosphate levels in patients taking abacavir once a day.

Harris, M., Back, D., Kewn, S., Jutha, S., Marina, R., & Montaner, J. S. G. (2002). Intracellular carbovir triphosphate levels in patients taking abacavir once a day.. AIDS (London, England), 16(8), 1196-1197. doi:10.1097/00002030-200205240-00021

DOI
10.1097/00002030-200205240-00021
Journal article

Therapeutic drug monitoring in HIV infection: current status and future directions.

Back, D., Gatti, G., Fletcher, C., Garaffo, R., Haubrich, R., Hoetelmans, R., . . . Perno, C. -F. (2002). Therapeutic drug monitoring in HIV infection: current status and future directions.. AIDS (London, England), 16 Suppl 1, S5-37. doi:10.1097/00002030-200203001-00002

DOI
10.1097/00002030-200203001-00002
Journal article

Absence of opioid withdrawal symptoms in patients receiving methadone and the protease inhibitor lopinavir-ritonavir

Clarke, S., Mulcahy, F., Bergin, C., Reynolds, H., Boyle, N., Barry, M., & Back, D. J. (2002). Absence of opioid withdrawal symptoms in patients receiving methadone and the protease inhibitor lopinavir-ritonavir. CLINICAL INFECTIOUS DISEASES, 34(8), 1143-1145. doi:10.1086/339541

DOI
10.1086/339541
Journal article

Determination of P-gp and MRP1 expression and function in peripheral blood mononuclear cells in vivo

Meaden, E. R., Hoggard, P. G., Khoo, S. H., & Back, D. J. (2002). Determination of P-gp and MRP1 expression and function in peripheral blood mononuclear cells in vivo. JOURNAL OF IMMUNOLOGICAL METHODS, 262(1-2), 159-165. doi:10.1016/S0022-1759(02)00020-0

DOI
10.1016/S0022-1759(02)00020-0
Journal article

Undefined duration of opiate withdrawal induced by efavirenz in drug users with HIV infection and undergoing chronic methadone treatment

Boffito, M., Rossati, A., Reynolds, H. E., Hoggard, P. G., Back, D. J., & Di Perri, G. (2002). Undefined duration of opiate withdrawal induced by efavirenz in drug users with HIV infection and undergoing chronic methadone treatment. AIDS RESEARCH AND HUMAN RETROVIRUSES, 18(5), 341-342. doi:10.1089/088922202753519115

DOI
10.1089/088922202753519115
Journal article

Erratum: Antiretroviral drug concentrations in semen of HIV-infected men: Differential penetration of indinavir, ritonavir and saquinavir (Journal of Antimicrobial Chemotherapy (2001) vol. 48 (351-354))

Taylor, S., Back, D. J., Drake, S. M., Workman, J., Reynolds, H., Gibbons, S. E., . . . Pillay, D. (2002). Erratum: Antiretroviral drug concentrations in semen of HIV-infected men: Differential penetration of indinavir, ritonavir and saquinavir (Journal of Antimicrobial Chemotherapy (2001) vol. 48 (351-354)). Journal of Antimicrobial Chemotherapy, 49(1), 227.

Journal article

CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir <i>in vitro</i>

Eagling, V. A., Wiltshire, H., Whitcombe, I. W. A., & Back, D. J. (2002). CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir <i>in vitro</i>. XENOBIOTICA, 32(1), 1-17. doi:10.1080/00498250110085845

DOI
10.1080/00498250110085845
Journal article

Development of enzymatic assays for quantification of intracellular lamivudine and carbovir triphosphate levels in peripheral blood mononuclear cells from human immunodeficiency virus-infected patients

Kewn, S., Hoggard, P. G., Sales, S. D., Jones, K., Maher, B., Khoo, S. H., & Back, D. J. (2002). Development of enzymatic assays for quantification of intracellular lamivudine and carbovir triphosphate levels in peripheral blood mononuclear cells from human immunodeficiency virus-infected patients. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 46(1), 135-143. doi:10.1128/AAC.46.1.135-143.2002

DOI
10.1128/AAC.46.1.135-143.2002
Journal article

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

Fellay, J., Marzolini, C., Meaden, E. R., Back, D. J., Buclin, T., Chave, J. P., . . . Telenti, A. (2002). Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. LANCET, 359(9300), 30-36. doi:10.1016/S0140-6736(02)07276-8

DOI
10.1016/S0140-6736(02)07276-8
Journal article

Intracellular accumulation of human immunodeficiency virus protease inhibitors

Khoo, S., Hoggard, P. G., Williams, I., Meaden, E. R., Newton, P., Wilkins, E. G., . . . Back, D. (2002). Intracellular accumulation of human immunodeficiency virus protease inhibitors. Antimicrob Agents Chemother, 46(10), 3228-3235.

Journal article

Intracellular pharmacology of nucleoside analogues and protease inhibitors: role of transporter molecules

Hoggard, P. G., & Back, D. J. (2002). Intracellular pharmacology of nucleoside analogues and protease inhibitors: role of transporter molecules. CURRENT OPINION IN INFECTIOUS DISEASES, 15(1), 3-8. doi:10.1097/00001432-200202000-00002

DOI
10.1097/00001432-200202000-00002
Journal article

Observations of HIV-1 genotypic drug resistance in a trial of four reverse transcriptase inhibitors (Quattro Trial).

Observations of HIV-1 genotypic drug resistance in a trial of four reverse transcriptase inhibitors (Quattro Trial). (2002). Antiviral therapy, 7(1), 11-20.

Journal article

Therapeutic Drug Monitoring in HIV infection:current status and future directions.

Back, D. J., Gatti, G., Fletcher, C., Garaffo, R., Haubrich, R., Hoetelmans, R., . . . Perno, C. F. (2002). Therapeutic Drug Monitoring in HIV infection:current status and future directions.. AIDS, 16(Suppl), S1-S35.

Journal article

Therapeutic drug monitoring

Back, D., Khoo, S., & Gibbons, S. (2002). Therapeutic drug monitoring. J Int Assoc Physicians AIDS Care (Chic), 1(3), 84-85.

Journal article

2001

Principles and practice of HIV-protease inhibitor pharmacoenhancement.

Moyle, G. J., & Back, D. (2001). Principles and practice of HIV-protease inhibitor pharmacoenhancement.. HIV medicine, 2(2), 105-113. doi:10.1046/j.1468-1293.2001.00063.x

DOI
10.1046/j.1468-1293.2001.00063.x
Journal article

Therapeutic drug monitoring as a tool in treating HIV infection

Khoo, S. H., Gibbons, S. E., & Back, D. J. (2001). Therapeutic drug monitoring as a tool in treating HIV infection. AIDS, 15, S171-S181. doi:10.1097/00002030-200100005-00021

DOI
10.1097/00002030-200100005-00021
Journal article

Zidovudine phosphorylation and mitochondrial toxicity <i>in vitro</i>

Sales, S. D., Hoggard, P. G., Sunderland, D., Khoo, S., Hart, C. A., & Back, D. J. (2001). Zidovudine phosphorylation and mitochondrial toxicity <i>in vitro</i>. TOXICOLOGY AND APPLIED PHARMACOLOGY, 177(1), 54-58. doi:10.1006/taap.2001.9288

DOI
10.1006/taap.2001.9288
Journal article

Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users

Clarke, S. M., Mulcahy, F. M., Tjia, J., Reynolds, H. E., Gibbons, S. E., Barry, M. G., & Back, D. J. (2001). Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users. CLINICAL INFECTIOUS DISEASES, 33(9), 1595-1597. doi:10.1086/322519

DOI
10.1086/322519
Journal article

Penetration of efavirenz into the male genital tract: drug concentrations and antiviral activity in semen and blood of HIV-1-infected men

Taylor, S., Reynolds, H., Sabin, C. A., Drake, S. M., White, D. J., Back, D. J., & Pillay, D. (2001). Penetration of efavirenz into the male genital tract: drug concentrations and antiviral activity in semen and blood of HIV-1-infected men. AIDS, 15(15), 2051-2053. doi:10.1097/00002030-200110190-00022

DOI
10.1097/00002030-200110190-00022
Journal article

Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients

Meaden, E. R., Hoggard, P. G., Maher, B., Khoo, S. H., & Back, D. J. (2001). Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients. AIDS RESEARCH AND HUMAN RETROVIRUSES, 17(14), 1329-1332. doi:10.1089/08892220152596588

DOI
10.1089/08892220152596588
Journal article

P-glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

Jones, K., Bray, P. G., Khoo, S. H., Davey, R. A., Meaden, E. R., Ward, S. A., & Back, D. J. (2001). P-glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?. AIDS, 15(11), 1353-1358. doi:10.1097/00002030-200107270-00004

DOI
10.1097/00002030-200107270-00004
Journal article

The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz

Clarke, S. M., Mulcahy, F. M., Tjia, J., Reynolds, H. E., Gibbons, S. E., Barry, M. G., & Back, D. J. (2001). The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 51(3), 213-217. doi:10.1046/j.1365-2125.2001.00342.x

DOI
10.1046/j.1365-2125.2001.00342.x
Journal article

The role of therapeutic drug monitoring in treatment of HIV infection

Back, D. J., Khoo, S. H., Gibbons, S. E., & Merry, C. (2001). The role of therapeutic drug monitoring in treatment of HIV infection. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 51(4), 301-308. doi:10.1046/j.1365-2125.2001.01380.x

DOI
10.1046/j.1365-2125.2001.01380.x
Journal article

Differences in the intracellular accumulation of HIV protease inhibitors <i>in vitro</i> and the effect of active transport

Jones, K., Hoggard, P. G., Sales, S. D., Khoo, S., Davey, R., & Back, D. J. (2001). Differences in the intracellular accumulation of HIV protease inhibitors <i>in vitro</i> and the effect of active transport. AIDS, 15(6), 675-681. doi:10.1097/00002030-200104130-00002

DOI
10.1097/00002030-200104130-00002
Journal article

Zidovudine phosphorylation determined sequentially over 12 months in human immunodeficiency virus-infected patients with or without previous exposure to antiretroviral agents

Hoggard, P. G., Lloyd, J., Khoo, S. H., Barry, M. G., Dann, L., Gibbons, S. E., . . . Back, D. J. (2001). Zidovudine phosphorylation determined sequentially over 12 months in human immunodeficiency virus-infected patients with or without previous exposure to antiretroviral agents. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 45(3), 976-980. doi:10.1128/AAC.35.3.976-980.2001

DOI
10.1128/AAC.35.3.976-980.2001
Journal article

Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir

Holladay, J. W., Dewey, M. J., Michniak, B. B., Wiltshire, H., Halberg, D. L., Weigl, P., . . . Back, D. J. (2001). Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir. DRUG METABOLISM AND DISPOSITION, 29(3), 299-303. Retrieved from https://www.webofscience.com/

Journal article

Effect of α<sub>1</sub>-acid glycoprotein on the intracellular accumulation of the HIV protease inhibitors saquinavir, ritonavir and indinavir <i>in vitro</i>

Jones, K., Hoggard, P. G., Khoo, S., Maher, B., & Back, D. J. (2001). Effect of α<sub>1</sub>-acid glycoprotein on the intracellular accumulation of the HIV protease inhibitors saquinavir, ritonavir and indinavir <i>in vitro</i>. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 51(1), 99-102. doi:10.1046/j.1365-2125.2001.01324.x

DOI
10.1046/j.1365-2125.2001.01324.x
Journal article

Influence of prior exposure to zidovudine on stavudine phosphorylation in vivo and ex vivo

Hoggard, P. G., Sales, S. D., Phiboonbanakit, D., Lloyd, J., Maher, B. A., Khoo, S. H., . . . Back, D. J. (2001). Influence of prior exposure to zidovudine on stavudine phosphorylation in vivo and ex vivo. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 45(2), 577-582. doi:10.1128/AAC.45.2.577-582.2001

DOI
10.1128/AAC.45.2.577-582.2001
Journal article

The pharmacogenomics of HIV therapy.

Pirmohamed, M., & Back, D. J. (2001). The pharmacogenomics of HIV therapy.. The pharmacogenomics journal, 1(4), 243-253. doi:10.1038/sj.tpj.6500069

DOI
10.1038/sj.tpj.6500069
Journal article

Therapeutic drug monitoring of anti-HIV drugs

Back, D. J., Khoo, S. H., Gibbons, S. E., Reynolds, H., Tjia, J. F., & Merry, C. (2001). Therapeutic drug monitoring of anti-HIV drugs. OPTIMAL DOSE IDENTIFICATION, 1220, 145-160. doi:10.1016/S0531-5131(01)00294-1

DOI
10.1016/S0531-5131(01)00294-1
Journal article

2000

The intracellular activation of lamivudine (3TC) and determination of 2′-deoxycytidine-5′-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells

Kewn, S., Hoggard, P. G., Sales, S. D., Johnson, M. A., & Back, D. J. (2000). The intracellular activation of lamivudine (3TC) and determination of 2′-deoxycytidine-5′-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 50(6), 597-604. Retrieved from https://www.webofscience.com/

Journal article

Untitled - Commentary

Back, D. J. (2000). Untitled - Commentary. In Unknown Book (Vol. 50, pp. 85). doi:10.1046/j.1365-2125.2000.00246.x

DOI
10.1046/j.1365-2125.2000.00246.x
Chapter

Pharmacokinetics of zidovudine phosphorylation in human immunodeficiency virus-positive Thai patients and healthy volunteers

Wattanagoon, Y., Bangchang, K. N., Hoggard, P. G., Khoo, S. H., Gibbons, S. E., Phiboonbhanakit, D., . . . Back, D. J. (2000). Pharmacokinetics of zidovudine phosphorylation in human immunodeficiency virus-positive Thai patients and healthy volunteers. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 44(7), 1986-1989. doi:10.1128/AAC.44.7.1986-1989.2000

DOI
10.1128/AAC.44.7.1986-1989.2000
Journal article

Pharmacological implications of lengthened in-utero exposure to nevirapine.

Taylor, G. P., Lyall, E. G., Back, D., Ward, C., & Tudor-Williams, G. (2000). Pharmacological implications of lengthened in-utero exposure to nevirapine.. Lancet (London, England), 355(9221), 2134-2135. doi:10.1016/s0140-6736(00)02383-7

DOI
10.1016/s0140-6736(00)02383-7
Journal article

Pharmacokinetics of nelfinavir and nevirapine in a patient with end-stage renal failure on continuous ambulatory peritoneal dialysis.

Taylor, S., Little, J., Halifax, K., Drake, S., & Back, D. (2000). Pharmacokinetics of nelfinavir and nevirapine in a patient with end-stage renal failure on continuous ambulatory peritoneal dialysis.. The Journal of antimicrobial chemotherapy, 45(5), 716-717. doi:10.1093/jac/45.5.716

DOI
10.1093/jac/45.5.716
Journal article

Therapeutic drug monitoring of antiretrovirals in human immunodeficiency virus infection

Back, D. J., Khoo, S. H., Gibbons, S. E., Barry, M. G., & Merry, C. (2000). Therapeutic drug monitoring of antiretrovirals in human immunodeficiency virus infection. THERAPEUTIC DRUG MONITORING, 22(1), 122-126. doi:10.1097/00007691-200002000-00026

DOI
10.1097/00007691-200002000-00026
Journal article

Correlation between intracellular pharmacological activation of nucleoside analogues and HIV suppression <i>in vitro</i>

Hoggard, P. G., Sales, S. D., Kewn, S., Sunderland, D., Khoo, S. H., Hart, C. A., & Back, D. J. (2000). Correlation between intracellular pharmacological activation of nucleoside analogues and HIV suppression <i>in vitro</i>. ANTIVIRAL CHEMISTRY & CHEMOTHERAPY, 11(6), 353-358. doi:10.1177/095632020001100601

DOI
10.1177/095632020001100601
Journal article

Current uses and future hopes for clinical pharmacology in the management of HIV infection.

Back, D., Khoo, S., Maher, B., & Gibbons, S. (2000). Current uses and future hopes for clinical pharmacology in the management of HIV infection.. HIV medicine, 1 Suppl 2, 12-17. doi:10.1046/j.1468-1293.2000.00001.x

DOI
10.1046/j.1468-1293.2000.00001.x
Journal article

Re: 'Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir'.

Back, D. J. (2000). Re: 'Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir'.. British journal of clinical pharmacology, 50(2), 85. doi:10.1046/j.1365-2125.2000.00246.x

DOI
10.1046/j.1365-2125.2000.00246.x
Journal article

1999

Effect of tuberculosis therapy on nevirapine trough plasma concentrations

Dean, G. L., Back, D. J., & de Ruiter, A. (1999). Effect of tuberculosis therapy on nevirapine trough plasma concentrations. AIDS, 13(17), 2489-2490. doi:10.1097/00002030-199912030-00029

DOI
10.1097/00002030-199912030-00029
Journal article

The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1.

Moore, K. H., Barrett, J. E., Shaw, S., Pakes, G. E., Churchus, R., Kapoor, A., . . . Back, D. (1999). The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1.. AIDS (London, England), 13(16), 2239-2250. doi:10.1097/00002030-199911120-00006

DOI
10.1097/00002030-199911120-00006
Journal article

Interaction of sildenafil and indinavir when co-administered to HIV-positive patients

Merry, C., Barry, M. G., Ryan, M., Tjia, J. F., Hennessy, M., Eagling, V. A., . . . Back, D. J. (1999). Interaction of sildenafil and indinavir when co-administered to HIV-positive patients. AIDS, 13(15), F101-F107. Retrieved from https://www.webofscience.com/

Journal article

Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-I protease inhibitor saquinavir by grapefruit juice components

Eagling, V. A., Profit, L., & Back, D. J. (1999). Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-I protease inhibitor saquinavir by grapefruit juice components. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 48(4), 543-552. Retrieved from https://www.webofscience.com/

Journal article

Pharmacological issues relating to viral resistance

Back, D. J. (1999). Pharmacological issues relating to viral resistance. In INFECTION Vol. 27 (pp. S42-S44). doi:10.1007/BF02561671

DOI
10.1007/BF02561671
Conference Paper

Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors

Profit, L., Eagling, V. A., & Back, D. J. (1999). Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. AIDS, 13(13), 1623-1627. doi:10.1097/00002030-199909100-00004

DOI
10.1097/00002030-199909100-00004
Journal article

The rabbit study: Ritonavir and saquinavir in combination in saquinavir-experienced and previously untreated patients

Churchill, D. R., Pym, A. S., Galpin, S., Foxall, R., Stainsby, C., Clarke, J. R., . . . Weber, J. N. (1999). The rabbit study: Ritonavir and saquinavir in combination in saquinavir-experienced and previously untreated patients. AIDS RESEARCH AND HUMAN RETROVIRUSES, 15(13), 1181-1189. doi:10.1089/088922299310278

DOI
10.1089/088922299310278
Journal article

Hydroxyurea-induced neurotoxicity in HIV disease.

Barry, M., Clarke, S., Mulcahy, F., & Back, D. (1999). Hydroxyurea-induced neurotoxicity in HIV disease.. AIDS (London, England), 13(12), 1592-1594. doi:10.1097/00002030-199908200-00028

DOI
10.1097/00002030-199908200-00028
Journal article

Intracellular activation of 2′,3′-dideoxyinosine and drug interactions <i>in vitro</i>

Kewn, S., Hoggard, P. G., Henry-Mowatt, J. S., Veal, G. J., Sales, S. D., Barry, M. G., & Back, D. J. (1999). Intracellular activation of 2′,3′-dideoxyinosine and drug interactions <i>in vitro</i>. AIDS RESEARCH AND HUMAN RETROVIRUSES, 15(9), 793-802. doi:10.1089/088922299310692

DOI
10.1089/088922299310692
Journal article

Preclinical and <i>in vitro</i> assessment of the potential of D0870, an antifungal agent, for producing clinical drug interactions

McKillop, D., Back, D. J., McCormick, A. D., Evans, J. A., & Tjia, J. (1999). Preclinical and <i>in vitro</i> assessment of the potential of D0870, an antifungal agent, for producing clinical drug interactions. XENOBIOTICA, 29(4), 395-408. doi:10.1080/004982599238579

DOI
10.1080/004982599238579
Journal article

Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection.

Barry, M., Mulcahy, F., Merry, C., Gibbons, S., & Back, D. (1999). Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection.. Clinical pharmacokinetics, 36(4), 289-304. doi:10.2165/00003088-199936040-00004

DOI
10.2165/00003088-199936040-00004
Journal article

Poor penetration of the male genital tract by HIV-1 protease inhibitors

Taylor, S., Back, D. J., Workman, J., Drake, S. M., White, D. J., Choudhury, B., . . . Pillay, D. (1999). Poor penetration of the male genital tract by HIV-1 protease inhibitors. AIDS, 13(7), 859-860. doi:10.1097/00002030-199905070-00017

DOI
10.1097/00002030-199905070-00017
Journal article

The effect of genetic polymorphisms in CYP2C9 on sulphamethoxazole <i>N</i>-hydroxylation

Gill, H. J., Tjia, J. F., Kitteringham, N. R., Pirmohamed, M., Back, D. J., & Park, B. K. (1999). The effect of genetic polymorphisms in CYP2C9 on sulphamethoxazole <i>N</i>-hydroxylation. PHARMACOGENETICS, 9(1), 43-53. doi:10.1097/00008571-199902000-00007

DOI
10.1097/00008571-199902000-00007
Journal article

1998

Effect of ribavirin on zidovudine efficacy and toxicity <i>in vitro</i>:: A concentration-dependent interaction

Sim, S. M., Hoggard, P. G., Sales, S. D., Phiboonbanakit, D., Hart, C. A., & Back, D. J. (1998). Effect of ribavirin on zidovudine efficacy and toxicity <i>in vitro</i>:: A concentration-dependent interaction. AIDS RESEARCH AND HUMAN RETROVIRUSES, 14(18), 1661-1667. doi:10.1089/aid.1998.14.1661

DOI
10.1089/aid.1998.14.1661
Journal article

Nelfinavir and nevirapine interaction?

Mulcahy, F., Barry, M., Merry, C., & Back, D. (1998). Nelfinavir and nevirapine interaction?. AIDS (London, England), 12(17), 2361.

Journal article

The role of CYP2C in the <i>in vitro</i> bioactivation of the contraceptive steroid desogestrel

Gentile, D. M., Verhoeven, C. H. J., Shimada, T., & Back, D. J. (1998). The role of CYP2C in the <i>in vitro</i> bioactivation of the contraceptive steroid desogestrel. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 287(3), 975-982. Retrieved from https://www.webofscience.com/

Journal article

Hyperlipidaemia following treatment with protease inhibitors in patients with HIV-I infection

Churchill, D. R., Pym, A. S., Babiker, A. G., Back, D. J., & Weber, J. N. (1998). Hyperlipidaemia following treatment with protease inhibitors in patients with HIV-I infection. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 46(5), 518-519. Retrieved from https://www.webofscience.com/

Journal article

The pharmacokinetics of combination therapy with nelfinavir plus nevirapine

Merry, C., Barry, M. G., Mulcahy, F., Ryan, M., Tjia, J. F., Halifax, K. L., . . . Back, D. J. (1998). The pharmacokinetics of combination therapy with nelfinavir plus nevirapine. AIDS, 12(10), 1163-1167. doi:10.1097/00002030-199810000-00008

DOI
10.1097/00002030-199810000-00008
Journal article

Variability in trough plasma saquinavir concentrations in HIV patients - a case for therapeutic drug monitoring

Barry, M. G., Merry, C., Lloyd, J., Halifax, K., Carey, P., Mulcahy, F., & Back, D. J. (1998). Variability in trough plasma saquinavir concentrations in HIV patients - a case for therapeutic drug monitoring. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 45(5), 501-502. Retrieved from https://www.webofscience.com/

Journal article

Antiretroviral therapy for patients with HIV disease

Barry, M., Mulcahy, F., & Back, D. J. (1998). Antiretroviral therapy for patients with HIV disease. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 45(3), 221-228. doi:10.1046/j.1365-2125.1998.00673.x

DOI
10.1046/j.1365-2125.1998.00673.x
Journal article

Ritonavir pharmacokinetics alone and in combination with saquinavir in HIV-infected patients

Merry, C., Barry, M. G., Mulcahy, F., Tjia, J. F., Halifax, K. L., Heavey, J., . . . Back, D. J. (1998). Ritonavir pharmacokinetics alone and in combination with saquinavir in HIV-infected patients. AIDS, 12(3), 325-327. Retrieved from https://www.webofscience.com/

Journal article

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

Eagling, V. A., Tjia, J. F., & Back, D. J. (1998). Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 45(2), 107-114. doi:10.1046/j.1365-2125.1998.00679.x

DOI
10.1046/j.1365-2125.1998.00679.x
Journal article

Effect of protease inhibitors on nucleoside analogue phosphorylation <i>in vitro</i>

Hoggard, P. G., Manion, V., Barry, M. G., & Back, D. J. (1998). Effect of protease inhibitors on nucleoside analogue phosphorylation <i>in vitro</i>. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 45(2), 164-167. doi:10.1046/j.1365-2125.1998.00660.x

DOI
10.1046/j.1365-2125.1998.00660.x
Journal article

Editorial

Editorial (1998). British Journal of Clinical Pharmacology, 45(2), 93. doi:10.1046/j.1365-2125.1998.00675.x

DOI
10.1046/j.1365-2125.1998.00675.x
Journal article

1997

Lack of effect of sibutramine an the efficacy of oral contraceptive steroids in healthy women

Back, D. J., Fearn, R., Oliver, S., Stott, D. A., & Wynne, R. D. (1997). Lack of effect of sibutramine an the efficacy of oral contraceptive steroids in healthy women. International Journal of Pharmaceutical Medicine, 11(2), 71-76.

Journal article

In vitro metabolism of dexamethasone (DEX) in human liver and kidney: The involvement of CYP3A4 and CYP17 (17,20 LYASE) and molecular modelling studies

Tomlinson, E. S., Lewis, D. F. V., Maggs, J. L., Kroemer, H. K., Park, B. K., & Back, D. J. (1997). In vitro metabolism of dexamethasone (DEX) in human liver and kidney: The involvement of CYP3A4 and CYP17 (17,20 LYASE) and molecular modelling studies. BIOCHEMICAL PHARMACOLOGY, 54(5), 605-611. doi:10.1016/S0006-2952(97)00166-4

DOI
10.1016/S0006-2952(97)00166-4
Journal article

Lamivudine (3TC) phosphorylation and drug interactions in vitro

Kewn, S., Veal, G. J., Hoggard, P. G., Barry, M. G., & Back, D. J. (1997). Lamivudine (3TC) phosphorylation and drug interactions in vitro. BIOCHEMICAL PHARMACOLOGY, 54(5), 589-595. doi:10.1016/S0006-2952(97)00189-5

DOI
10.1016/S0006-2952(97)00189-5
Journal article

Dexamethasone metabolism in vitro: Species differences

Tomlinson, E. S., Maggs, J. L., Park, B. K., & Back, D. J. (1997). Dexamethasone metabolism in vitro: Species differences. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 62(4), 345-352. doi:10.1016/S0960-0760(97)00038-1

DOI
10.1016/S0960-0760(97)00038-1
Journal article

In vitro screening of nucleoside analog combinations for potential use in anti-HIV therapy

Veal, G. J., Barry, M. G., Khoo, S. H., & Back, D. J. (1997). In vitro screening of nucleoside analog combinations for potential use in anti-HIV therapy. AIDS RESEARCH AND HUMAN RETROVIRUSES, 13(6), 481-484. doi:10.1089/aid.1997.13.481

DOI
10.1089/aid.1997.13.481
Journal article

Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients

Merry, C., Barry, M. G., Mulcahy, F., Ryan, M., Heavey, J., Tjia, J. F., . . . Back, D. J. (1997). Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients. AIDS, 11(4), F29-F33. doi:10.1097/00002030-199704000-00001

DOI
10.1097/00002030-199704000-00001
Journal article

Saquinavir interaction with midazolam: pharmacokinetic considerations when prescribing protease inhibitors for patients with HIV disease.

Merry, C., Mulcahy, F., Barry, M., Gibbons, S., & Back, D. (1997). Saquinavir interaction with midazolam: pharmacokinetic considerations when prescribing protease inhibitors for patients with HIV disease.. AIDS (London, England), 11(2), 268-269.

Journal article

Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

Eagling, V. A., Back, D. J., & Barry, M. G. (1997). Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 44(2), 190-194. doi:10.1046/j.1365-2125.1997.00644.x

DOI
10.1046/j.1365-2125.1997.00644.x
Journal article

Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro

Hoggard, P. G., Kewn, S., Barry, M. G., Khoo, S. H., & Back, D. J. (1997). Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 41(6), 1231-1236. doi:10.1128/AAC.41.6.1231

DOI
10.1128/AAC.41.6.1231
Journal article

Erratum: 'Lack of effect of sibutramine on the efficacy of oral contraceptive steroids in healthy women' (International Journal of Pharmaceutical Medicine (1997) 11 (71-76))

Back, D. J., Fearn, R., Stott, D. A., & Wynne, R. D. (1997). Erratum: 'Lack of effect of sibutramine on the efficacy of oral contraceptive steroids in healthy women' (International Journal of Pharmaceutical Medicine (1997) 11 (71-76)). International Journal of Pharmaceutical Medicine, 11(4), 244.

Journal article

Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations.

Barry, M., Gibbons, S., Back, D., & Mulcahy, F. (1997). Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations.. Clinical pharmacokinetics, 32(3), 194-209. doi:10.2165/00003088-199732030-00003

DOI
10.2165/00003088-199732030-00003
Journal article

Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients

Merry, C., Barry, M. G., Mulcahy, F., Halifax, K. L., & Back, D. J. (1997). Saquinavir pharmacokinetics alone and in combination with nelfinavir in HIV-infected patients. AIDS, 11(15), F117-F120. doi:10.1097/00002030-199715000-00001

DOI
10.1097/00002030-199715000-00001
Journal article

1996

Intracellular metabolism of zidovudine and stavudine in combination.

Hoggard, P., Khoo, S., Barry, M., & Back, D. (1996). Intracellular metabolism of zidovudine and stavudine in combination.. The Journal of infectious diseases, 174(3), 671-672. doi:10.1093/infdis/174.3.671

DOI
10.1093/infdis/174.3.671
Journal article

Lack of association between schizophrenia and the CYP2D6 gene polymorphisms

Pirmohamed, M., Wild, M. J., Kitteringham, N. R., OBrien, K., Buchan, I. E., Back, D. J., & Park, B. K. (1996). Lack of association between schizophrenia and the CYP2D6 gene polymorphisms. AMERICAN JOURNAL OF MEDICAL GENETICS, 67(2), 236-237. doi:10.1002/ajmg.1320670205

DOI
10.1002/ajmg.1320670205
Journal article

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

Gentile, D. M., Tomlinson, E. S., Maggs, J. L., Park, B. K., & Back, D. J. (1996). Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 277(1), 105-112. Retrieved from https://www.webofscience.com/

Journal article

Theophylline metabolism in human liver microsomes: Inhibition studies

Tjia, J. F., Colbert, J., & Back, D. J. (1996). Theophylline metabolism in human liver microsomes: Inhibition studies. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 276(3), 912-917. Retrieved from https://www.webofscience.com/

Journal article

Dexamethasone metabolism in vitro: Species differences in 6-hydroxylation

Tomlinson, E. S., Maggs, J. L., Park, B. K., & Back, D. J. (1996). Dexamethasone metabolism in vitro: Species differences in 6-hydroxylation. British Journal of Clinical Pharmacology, 41(5).

Journal article

How important is the pharmacokinetics issue for the pharmacodynamic diversity of oral contraceptives?

Back, D. J. (1996). How important is the pharmacokinetics issue for the pharmacodynamic diversity of oral contraceptives?. Gynecological Endocrinology, 10(sup2), 31-34. doi:10.3109/09513599609045624

DOI
10.3109/09513599609045624
Journal article

Impaired absorption of zidovudine in patients with AIDS-related small intestinal disease.

Kapembwa, M. S., Fleming, S. C., Orr, M., Wells, C., Bland, M., Back, D., & Griffin, G. E. (1996). Impaired absorption of zidovudine in patients with AIDS-related small intestinal disease.. AIDS (London, England), 10(13), 1509-1514. doi:10.1097/00002030-199611000-00008

DOI
10.1097/00002030-199611000-00008
Journal article

Interaction between lamivudine (3TC) and other nucleoside analogues for intracellular phosphorylation

Veal, G. J., Hoggard, P. G., Barry, M. G., Khoo, S., & Back, D. J. (1996). Interaction between lamivudine (3TC) and other nucleoside analogues for intracellular phosphorylation. AIDS, 10(5), 546-548. doi:10.1097/00002030-199605000-00016

DOI
10.1097/00002030-199605000-00016
Journal article

The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites

Barry, M. G., Khoo, S. H., Veal, G. J., Hoggard, P. G., Gibbons, S. E., Wilkins, E. G. L., . . . Back, D. J. (1996). The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites. AIDS, 10(12), 1361-1367. doi:10.1097/00002030-199610000-00008

DOI
10.1097/00002030-199610000-00008
Journal article

1995

EFFECT OF AZOLES ON THE GLUCURONIDATION OF ZIDOVUDINE BY HUMAN LIVER UDP-GLUCURONOSYLTRANSFERASE

ASGARI, M., & BACK, D. J. (1995). EFFECT OF AZOLES ON THE GLUCURONIDATION OF ZIDOVUDINE BY HUMAN LIVER UDP-GLUCURONOSYLTRANSFERASE. JOURNAL OF INFECTIOUS DISEASES, 172(6), 1634-1635. doi:10.1093/infdis/172.6.1634

DOI
10.1093/infdis/172.6.1634
Journal article

PARACETAMOL DISPOSITION IN THAI PATIENTS DURING AND AFTER TREATMENT OF FALCIPARUM-MALARIA

ISMAIL, S., BANGCHANG, K. N., KARBWANG, J., BACK, D. J., & EDWARDS, G. (1995). PARACETAMOL DISPOSITION IN THAI PATIENTS DURING AND AFTER TREATMENT OF FALCIPARUM-MALARIA. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 48(1), 65-69. Retrieved from https://www.webofscience.com/

Journal article

DRUG-INTERACTIONS WITH ZIDOVUDINE PHOSPHORYLATION IN-VITRO

HOGGARD, P. G., VEAL, G. J., WILD, M. J., BARRY, M. G., & BACK, D. J. (1995). DRUG-INTERACTIONS WITH ZIDOVUDINE PHOSPHORYLATION IN-VITRO. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 39(6), 1376-1378. doi:10.1128/AAC.39.6.1376

DOI
10.1128/AAC.39.6.1376
Journal article

INFLUENCE OF HIGH-DOSES OF VITAMIN-C ON THE BIOAVAILABILITY AND THE SERUM-PROTEIN BINDING OF LEVONORGESTREL IN WOMEN USING A COMBINATION ORAL-CONTRACEPTIVE

KUHNZ, W., LOUTON, T., HUMPEL, M., BACK, D. J., & ZAMAH, N. M. (1995). INFLUENCE OF HIGH-DOSES OF VITAMIN-C ON THE BIOAVAILABILITY AND THE SERUM-PROTEIN BINDING OF LEVONORGESTREL IN WOMEN USING A COMBINATION ORAL-CONTRACEPTIVE. CONTRACEPTION, 51(2), 111-116. doi:10.1016/0010-7824(94)00016-P

DOI
10.1016/0010-7824(94)00016-P
Journal article

Metabolism of zidovudine

Veal, G. J., & Back, D. J. (1995). Metabolism of zidovudine. GENERAL PHARMACOLOGY, 26(7), 1469-1475. doi:10.1016/0306-3623(95)00047-X

DOI
10.1016/0306-3623(95)00047-X
Journal article

Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in children with HIV infection.

Gibb, D., Barry, M., Ormesher, S., Nokes, L., Seefried, M., Giaquinto, C., & Back, D. (1995). Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in children with HIV infection.. British journal of clinical pharmacology, 39(5), 527-530. doi:10.1111/j.1365-2125.1995.tb04490.x

DOI
10.1111/j.1365-2125.1995.tb04490.x
Journal article

ZALCITABINE (DDC) PHOSPHORYLATION AND DRUG-INTERACTIONS

VEAL, G. J., BARRY, M. G., & BACK, D. J. (1995). ZALCITABINE (DDC) PHOSPHORYLATION AND DRUG-INTERACTIONS. ANTIVIRAL CHEMISTRY & CHEMOTHERAPY, 6(6), 379-384. doi:10.1177/095632029500600605

DOI
10.1177/095632029500600605
Journal article

ZIDOVUDINE THERAPY IN HIV-INFECTION - WHICH PATIENTS SHOULD BE TREATED AND WHEN

BARRY, M. G., BACK, D. J., & BRECKENRIDGE, A. M. (1995). ZIDOVUDINE THERAPY IN HIV-INFECTION - WHICH PATIENTS SHOULD BE TREATED AND WHEN. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 40(2), 107-110. doi:10.1111/j.1365-2125.1995.tb05765.x

DOI
10.1111/j.1365-2125.1995.tb05765.x
Journal article

1994

An evaluation of the interaction between tiagabine and oral contraceptives in female volunteers

Mengel, H. B., Houston, A., & Back, D. J. (1994). An evaluation of the interaction between tiagabine and oral contraceptives in female volunteers. Journal of Pharmaceutical Medicine, 4(3), 141-150.

Journal article

THE METABOLISM OF ZIDOVUDINE BY HUMAN LIVER-MICROSOMES IN-VITRO - FORMATION OF 3'-AMINO-3'-DEOXYTHYMIDINE

EAGLING, V. A., HOWE, J. L., BARRY, M. J., & BACK, D. J. (1994). THE METABOLISM OF ZIDOVUDINE BY HUMAN LIVER-MICROSOMES IN-VITRO - FORMATION OF 3'-AMINO-3'-DEOXYTHYMIDINE. BIOCHEMICAL PHARMACOLOGY, 48(2), 267-276. doi:10.1016/0006-2952(94)90097-3

DOI
10.1016/0006-2952(94)90097-3
Journal article

PHARMACOKINETICS OF MEFLOQUINE ALONE OR IN COMBINATION WITH ARTESUNATE

KARBWANG, J., BANGCHANG, K. N., THANAVIBUL, A., BACK, D. J., BUNNAG, D., & HARINASUTA, T. (1994). PHARMACOKINETICS OF MEFLOQUINE ALONE OR IN COMBINATION WITH ARTESUNATE. BULLETIN OF THE WORLD HEALTH ORGANIZATION, 72(1), 83-87. Retrieved from https://www.webofscience.com/

Journal article

EFFECT OF MALARIA INFECTION ON THE PHARMACOKINETICS OF PARACETAMOL IN RAT

ISMAIL, S., KOKWARO, G. O., BACK, D. J., & EDWARDS, G. (1994). EFFECT OF MALARIA INFECTION ON THE PHARMACOKINETICS OF PARACETAMOL IN RAT. XENOBIOTICA, 24(6), 527-533. doi:10.3109/00498259409043255

DOI
10.3109/00498259409043255
Journal article

EFFECTS OF DIDEOXYINOSINE AND DIDEOXYCYTIDINE ON THE INTRACELLULAR PHOSPHORYLATION OF ZIDOVUDINE IN HUMAN MONONUCLEAR-CELLS

VEAL, G. J., WILD, M. J., BARRY, M. G., & BACK, D. J. (1994). EFFECTS OF DIDEOXYINOSINE AND DIDEOXYCYTIDINE ON THE INTRACELLULAR PHOSPHORYLATION OF ZIDOVUDINE IN HUMAN MONONUCLEAR-CELLS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 38(4), 323-328. doi:10.1111/j.1365-2125.1994.tb04361.x

DOI
10.1111/j.1365-2125.1994.tb04361.x
Journal article

PHARMACOKINETICS OF ZIDOVUDINE AND DIDEOXYINOSINE ALONE AND IN COMBINATION IN PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME

BARRY, M., HOWE, J. L., ORMESHER, S., BACK, D. J., BRECKENRIDGE, A. M., BERGIN, C., . . . NYE, F. (1994). PHARMACOKINETICS OF ZIDOVUDINE AND DIDEOXYINOSINE ALONE AND IN COMBINATION IN PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 37(5), 421-426. doi:10.1111/j.1365-2125.1994.tb05708.x

DOI
10.1111/j.1365-2125.1994.tb05708.x
Journal article

PHARMACOKINETICS OF ZIDOVUDINE IN CHILDREN WITH SYMPTOMATIC HIV-INFECTION

BARRY, M., HOWE, J. L., BACK, D. J., HAN, I., & GIBB, D. (1994). PHARMACOKINETICS OF ZIDOVUDINE IN CHILDREN WITH SYMPTOMATIC HIV-INFECTION. DRUG INVESTIGATION, 7(3), 143-147. doi:10.1007/BF03258466

DOI
10.1007/BF03258466
Journal article

ZIDOVUDINE PHARMACOKINETICS IN ZIDOVUDINE-INDUCED BONE-MARROW TOXICITY

BARRY, M., HOWE, J. L., BACK, D. J., SWART, A. M., BRECKENRIDGE, A. M., WELLER, I. V. D., . . . NYE, F. (1994). ZIDOVUDINE PHARMACOKINETICS IN ZIDOVUDINE-INDUCED BONE-MARROW TOXICITY. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 37(1), 7-12. doi:10.1111/j.1365-2125.1994.tb04231.x

DOI
10.1111/j.1365-2125.1994.tb04231.x
Journal article

ZIDOVUDINE PHOSPHORYLATION IN HIV-INFECTED PATIENTS AND SERONEGATIVE VOLUNTEERS

BARRY, M., WILD, M., VEAL, G., BACK, D., BRECKENRIDGE, A., FOX, R., . . . TIMMINS, D. (1994). ZIDOVUDINE PHOSPHORYLATION IN HIV-INFECTED PATIENTS AND SERONEGATIVE VOLUNTEERS. AIDS, 8(8), F1-F5. doi:10.1097/00002030-199408000-00002

DOI
10.1097/00002030-199408000-00002
Journal article

1993

Pharmacokinetics and protein binding of 3-ketodesogestrel and gestodene in the serum of women during 6 cycles of treatment with two low dose oral contraceptives.

Back, D. J., Power, J., Winkler, U., Schindler, A. E., Daume, E., Simon, A., . . . Hammerstein, J. (1993). Pharmacokinetics and protein binding of 3-ketodesogestrel and gestodene in the serum of women during 6 cycles of treatment with two low dose oral contraceptives.. Advances in contraception : the official journal of the Society for the Advancement of Contraception, 9(4), 319-330. doi:10.1007/bf01983210

DOI
10.1007/bf01983210
Journal article

EFFECT OF CHLORMETHIAZOLE ON HEPATIC MONOOXYGENASES ACTIVITY INVIVO

MONIG, H., BACK, D. J., HEIDEMANN, H. T., OHNHAUS, E. E., BROCKMANN, B., & SCHULTE, H. M. (1993). EFFECT OF CHLORMETHIAZOLE ON HEPATIC MONOOXYGENASES ACTIVITY INVIVO. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 44(2), 203-204. doi:10.1007/BF00315482

DOI
10.1007/BF00315482
Journal article

ABSENCE OF AN EFFECT OF HIGH VITAMIN-C DOSAGE ON THE SYSTEMIC AVAILABILITY OF ETHINYL ESTRADIOL IN WOMEN USING A COMBINATION ORAL-CONTRACEPTIVE

ZAMAH, N. M., HUMPEL, M., KUHNZ, W., LOUTON, T., RAFFERTY, J., & BACK, D. J. (1993). ABSENCE OF AN EFFECT OF HIGH VITAMIN-C DOSAGE ON THE SYSTEMIC AVAILABILITY OF ETHINYL ESTRADIOL IN WOMEN USING A COMBINATION ORAL-CONTRACEPTIVE. CONTRACEPTION, 48(4), 377-391. doi:10.1016/0010-7824(93)90083-J

DOI
10.1016/0010-7824(93)90083-J
Journal article

CORTISOL METABOLISM BY HUMAN LIVER IN-VITRO .4. METABOLISM OF 9-ALPHA-FLUOROCORTISOL BY HUMAN LIVER-MICROSOMES AND CYTOSOL

ABEL, S. M., BACK, D. J., MAGGS, J. L., & PARK, B. K. (1993). CORTISOL METABOLISM BY HUMAN LIVER IN-VITRO .4. METABOLISM OF 9-ALPHA-FLUOROCORTISOL BY HUMAN LIVER-MICROSOMES AND CYTOSOL. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 46(6), 833-839. doi:10.1016/0960-0760(93)90326-R

DOI
10.1016/0960-0760(93)90326-R
Journal article

CORTISOL METABOLISM IN-VITRO .3. INHIBITION OF MICROSOMAL 6-BETA-HYDROXYLASE AND CYTOSOLIC 4-ENE-REDUCTASE

ABEL, S. M., & BACK, D. J. (1993). CORTISOL METABOLISM IN-VITRO .3. INHIBITION OF MICROSOMAL 6-BETA-HYDROXYLASE AND CYTOSOLIC 4-ENE-REDUCTASE. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 46(6), 827-832. doi:10.1016/0960-0760(93)90325-Q

DOI
10.1016/0960-0760(93)90325-Q
Journal article

CORTISOL METABOLISM INVITRO .2. SPECIES-DIFFERENCE

ABEL, S. M., BACK, D. J., MAGGS, J. L., & PARK, B. K. (1993). CORTISOL METABOLISM INVITRO .2. SPECIES-DIFFERENCE. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 45(5), 445-453. doi:10.1016/0960-0760(93)90013-M

DOI
10.1016/0960-0760(93)90013-M
Journal article

EFFECT OF ETRETINATE ON CYCLOSPORINE METABOLISM INVITRO

WEBBER, I. R., & BACK, D. J. (1993). EFFECT OF ETRETINATE ON CYCLOSPORINE METABOLISM INVITRO. BRITISH JOURNAL OF DERMATOLOGY, 128(1), 42-44. doi:10.1111/j.1365-2133.1993.tb00145.x

DOI
10.1111/j.1365-2133.1993.tb00145.x
Journal article

INFLUENCE OF GESTODENE AND DESOGESTREL AS COMPONENTS OF LOW-DOSE ORAL-CONTRACEPTIVES ON THE PHARMACOKINETICS OF ETHINYL ESTRADIOL (EE2), ON SERUM CBG AND ON URINARY CORTISOL AND 6-BETA-HYDROXYCORTISOL

HAMMERSTEIN, J., DAUME, E., SIMON, A., WINKLER, U. H., SCHINDLER, A. E., BACK, D. J., . . . NEISS, A. (1993). INFLUENCE OF GESTODENE AND DESOGESTREL AS COMPONENTS OF LOW-DOSE ORAL-CONTRACEPTIVES ON THE PHARMACOKINETICS OF ETHINYL ESTRADIOL (EE2), ON SERUM CBG AND ON URINARY CORTISOL AND 6-BETA-HYDROXYCORTISOL. CONTRACEPTION, 47(3), 263-281. doi:10.1016/0010-7824(93)90043-7

DOI
10.1016/0010-7824(93)90043-7
Journal article

METABOLISM OF DIDANOSINE (DDI) BY ERYTHROCYTES - PHARMACOKINETIC IMPLICATIONS

BARRY, M., BACK, D., ORMESHER, S., BEECHING, N., & NYE, F. (1993). METABOLISM OF DIDANOSINE (DDI) BY ERYTHROCYTES - PHARMACOKINETIC IMPLICATIONS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 36(1), 87-88. doi:10.1111/j.1365-2125.1993.tb05899.x

DOI
10.1111/j.1365-2125.1993.tb05899.x
Journal article

METABOLISM OF GESTODENE IN HUMAN LIVER CYTOSOL AND MICROSOMES IN-VITRO

WARD, S., & BACK, D. J. (1993). METABOLISM OF GESTODENE IN HUMAN LIVER CYTOSOL AND MICROSOMES IN-VITRO. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 46(2), 235-243. doi:10.1016/0960-0760(93)90299-C

DOI
10.1016/0960-0760(93)90299-C
Journal article

METABOLISM OF THE ORAL-CONTRACEPTIVE STEROIDS ETHYNYLESTRADIOL, NORGESTIMATE AND 3-KETODESOGESTREL BY A HUMAN ENDOMETRIAL CANCER CELL-LINE (HEC-1A) AND ENDOMETRIAL TISSUE INVITRO

WILD, M. J., RUDLAND, P. S., & BACK, D. J. (1993). METABOLISM OF THE ORAL-CONTRACEPTIVE STEROIDS ETHYNYLESTRADIOL, NORGESTIMATE AND 3-KETODESOGESTREL BY A HUMAN ENDOMETRIAL CANCER CELL-LINE (HEC-1A) AND ENDOMETRIAL TISSUE INVITRO. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 45(5), 407-420. doi:10.1016/0960-0760(93)90010-T

DOI
10.1016/0960-0760(93)90010-T
Journal article

Radioimmunological analysis of ethinylestradiol in human serum. Validation of the method and comparison with a gas chromatographic/mass spectrometric assay.

Kuhnz, W., Louton, T., Back, D. J., & Michaelis, K. (1993). Radioimmunological analysis of ethinylestradiol in human serum. Validation of the method and comparison with a gas chromatographic/mass spectrometric assay.. Arzneimittel-Forschung, 43(1), 16-21.

Journal article

THE EFFECTS OF INDOMETHACIN AND NAPROXEN ON ZIDOVUDINE PHARMACOKINETICS

BARRY, M., HOWE, J., BACK, D., BRECKENRIDGE, A., BRETTLE, R., MITCHELL, R., . . . NYE, F. J. (1993). THE EFFECTS OF INDOMETHACIN AND NAPROXEN ON ZIDOVUDINE PHARMACOKINETICS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 36(1), 82-85. doi:10.1111/j.1365-2125.1993.tb05898.x

DOI
10.1111/j.1365-2125.1993.tb05898.x
Journal article

1992

THE EFFECT OF MALARIA INFECTION ON 3'-AZIDO-3'-DEOXYTHYMIDINE AND PARACETAMOL GLUCURONIDATION IN RAT-LIVER MICROSOMES

ISMAIL, S., BACK, D. J., & EDWARDS, G. (1992). THE EFFECT OF MALARIA INFECTION ON 3'-AZIDO-3'-DEOXYTHYMIDINE AND PARACETAMOL GLUCURONIDATION IN RAT-LIVER MICROSOMES. BIOCHEMICAL PHARMACOLOGY, 44(9), 1879-1882. doi:10.1016/0006-2952(92)90084-V

DOI
10.1016/0006-2952(92)90084-V
Journal article

EFFECT OF TETRACYCLINE ON MEFLOQUINE PHARMACOKINETICS IN THAI MALES

KARBWANG, J., BANGCHANG, K. N., BACK, D. J., BUNNAG, D., & ROONEY, W. (1992). EFFECT OF TETRACYCLINE ON MEFLOQUINE PHARMACOKINETICS IN THAI MALES. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 43(5), 567-569. doi:10.1007/BF02285105

DOI
10.1007/BF02285105
Journal article

PRIMAQUINE METABOLISM BY HUMAN LIVER-MICROSOMES - EFFECT OF OTHER ANTIMALARIAL-DRUGS

BANGCHANG, K. N., KARBWANG, J., & BACK, D. J. (1992). PRIMAQUINE METABOLISM BY HUMAN LIVER-MICROSOMES - EFFECT OF OTHER ANTIMALARIAL-DRUGS. BIOCHEMICAL PHARMACOLOGY, 44(3), 587-590. doi:10.1016/0006-2952(92)90453-P

DOI
10.1016/0006-2952(92)90453-P
Journal article

Loss of taste and terbinafine.

Back, D. (1992). Loss of taste and terbinafine.. Lancet (London, England), 340(8813), 252. doi:10.1016/0140-6736(92)90528-b

DOI
10.1016/0140-6736(92)90528-b
Journal article

MEFLOQUINE METABOLISM BY HUMAN LIVER-MICROSOMES - EFFECT OF OTHER ANTIMALARIAL-DRUGS

BANGCHANG, K. N., KARBWANG, J., & BACK, D. J. (1992). MEFLOQUINE METABOLISM BY HUMAN LIVER-MICROSOMES - EFFECT OF OTHER ANTIMALARIAL-DRUGS. BIOCHEMICAL PHARMACOLOGY, 43(9), 1957-1961. doi:10.1016/0006-2952(92)90638-Y

DOI
10.1016/0006-2952(92)90638-Y
Journal article

PHARMACOKINETICS OF MEFLOQUINE IN THE PRESENCE OF PRIMAQUINE

KARBWANG, J., BANGCHANG, K. N., THANAVIBUL, A., BACK, D. J., & BUNNAG, D. (1992). PHARMACOKINETICS OF MEFLOQUINE IN THE PRESENCE OF PRIMAQUINE. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 42(5), 559-560. doi:10.1007/BF00314870

DOI
10.1007/BF00314870
Journal article

INVITRO INHIBITION STUDIES OF THE GLUCURONIDATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE CATALYZED BY HUMAN LIVER UDP-GLUCURONOSYL TRANSFERASE

MACLEOD, R., EAGLING, V. A., SIM, S. M., & BACK, D. J. (1992). INVITRO INHIBITION STUDIES OF THE GLUCURONIDATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE CATALYZED BY HUMAN LIVER UDP-GLUCURONOSYL TRANSFERASE. BIOCHEMICAL PHARMACOLOGY, 43(2), 382-386. doi:10.1016/0006-2952(92)90303-Z

DOI
10.1016/0006-2952(92)90303-Z
Journal article

RELATIVE EXPRESSION OF CYTOCHROME P450 ISOENZYMES IN HUMAN LIVER AND ASSOCIATION WITH THE METABOLISM OF DRUGS AND XENOBIOTICS

FORRESTER, L. M., HENDERSON, C. J., GLANCEY, M. J., BACK, D. J., PARK, B. K., BALL, S. E., . . . WOLF, C. R. (1992). RELATIVE EXPRESSION OF CYTOCHROME P450 ISOENZYMES IN HUMAN LIVER AND ASSOCIATION WITH THE METABOLISM OF DRUGS AND XENOBIOTICS. BIOCHEMICAL JOURNAL, 281, 359-368. doi:10.1042/bj2810359

DOI
10.1042/bj2810359
Journal article

AZOLES, ALLYLAMINES AND DRUG-METABOLISM

BACK, D. J., TJIA, J. F., & ABEL, S. M. (1992). AZOLES, ALLYLAMINES AND DRUG-METABOLISM. BRITISH JOURNAL OF DERMATOLOGY, 126, 14-18. doi:10.1111/j.1365-2133.1992.tb00003.x

DOI
10.1111/j.1365-2133.1992.tb00003.x
Journal article

Bacterial and hepatic metabolism of zidovudine (AZT) to the toxic catabolite 3'-amino-3'-deoxythymidine (AMT)

Howe, J. L., Back, D. J., Eagling, V., & Hart, C. A. (1992). Bacterial and hepatic metabolism of zidovudine (AZT) to the toxic catabolite 3'-amino-3'-deoxythymidine (AMT). In British Journal of Clinical Pharmacology Vol. 34.

Conference Paper

CORTISOL METABOLISM BY HUMAN LIVER INVITRO .1. METABOLITE IDENTIFICATION AND INTERINDIVIDUAL VARIABILITY

ABEL, S. M., MAGGS, J. L., BACK, D. J., & PARK, B. K. (1992). CORTISOL METABOLISM BY HUMAN LIVER INVITRO .1. METABOLITE IDENTIFICATION AND INTERINDIVIDUAL VARIABILITY. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 43(7), 713-719. doi:10.1016/0960-0760(92)90297-V

DOI
10.1016/0960-0760(92)90297-V
Journal article

CYCLOSPORINE METABOLISM BY HUMAN GASTROINTESTINAL MUCOSAL MICROSOMES

WEBBER, I. R., PETERS, W. H. M., & BACK, D. J. (1992). CYCLOSPORINE METABOLISM BY HUMAN GASTROINTESTINAL MUCOSAL MICROSOMES. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 33(6), 661-664. doi:10.1111/j.1365-2125.1992.tb04098.x

DOI
10.1111/j.1365-2125.1992.tb04098.x
Journal article

Cortisol metabolism by human liver in vitro

Abel, S. M., Maggs, J. L., Back, D. J., Newby, S., Colbert, J., & Park, B. K. (1992). Cortisol metabolism by human liver in vitro. In British Journal of Clinical Pharmacology Vol. 33.

Conference Paper

EXTRAHEPATIC METABOLISM OF ZIDOVUDINE

HOWE, J. L., BACK, D. J., & COLBERT, J. (1992). EXTRAHEPATIC METABOLISM OF ZIDOVUDINE. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 33(2), 190-192. doi:10.1111/j.1365-2125.1992.tb04024.x

DOI
10.1111/j.1365-2125.1992.tb04024.x
Journal article

METABOLISM OF 2',3'-DIDEOXYINOSINE (DDI) IN HUMAN BLOOD

BACK, D. J., ORMESHER, S., TJIA, J. F., & MACLEOD, R. (1992). METABOLISM OF 2',3'-DIDEOXYINOSINE (DDI) IN HUMAN BLOOD. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 33(3), 319-322. doi:10.1111/j.1365-2125.1992.tb04043.x

DOI
10.1111/j.1365-2125.1992.tb04043.x
Journal article

Metabolism of contraceptive steroids by human endometrial tissue and an endometrial cancer cell-line (HEC-1A) in vitro

Wild, M. J., Back, D. J., & Rudland, P. S. (1992). Metabolism of contraceptive steroids by human endometrial tissue and an endometrial cancer cell-line (HEC-1A) in vitro. In British Journal of Clinical Pharmacology Vol. 33.

Conference Paper

Metabolism of the oral contraceptive steroid gestodene by human liver in vitro

Ward, S., & Back, D. J. (1992). Metabolism of the oral contraceptive steroid gestodene by human liver in vitro. In British Journal of Clinical Pharmacology Vol. 34.

Conference Paper

Pharmacokinetics and serum protein binding of 3-keto-desogestrel in women during three cycles of treatment with a low-dose combination oral contraceptive.

Kuhnz, W., al-Yacoub, G., Power, J., Ormesher, S. E., Back, D. J., & Jütting, G. (1992). Pharmacokinetics and serum protein binding of 3-keto-desogestrel in women during three cycles of treatment with a low-dose combination oral contraceptive.. Arzneimittel-Forschung, 42(9), 1142-1146.

Journal article

Pharmacokinetics and serum protein binding of gestodene and 3-keto-desogestrel in women after single oral administration of two different contraceptive formulations.

Kuhnz, W., Schütt, B., Power, J., & Back, D. J. (1992). Pharmacokinetics and serum protein binding of gestodene and 3-keto-desogestrel in women after single oral administration of two different contraceptive formulations.. Arzneimittel-Forschung, 42(9), 1139-1141.

Journal article

Species differences in the in vitro metabolism of cortisol

Abel, S. M., Back, D. J., Maggs, J. L., & Park, B. K. (1992). Species differences in the in vitro metabolism of cortisol. In British Journal of Clinical Pharmacology Vol. 34.

Conference Paper

The in-vitro mucosal conjugation of ethinyloestradiol and the bioavailability of oral contraceptive steroids in patients with treated and untreated coeliac disease.

Grimmer, S. F., Back, D. J., Orme, M. L., Tjia, J. F., Gilmore, I. T., & Ellis, A. (1992). The in-vitro mucosal conjugation of ethinyloestradiol and the bioavailability of oral contraceptive steroids in patients with treated and untreated coeliac disease.. Alimentary pharmacology & therapeutics, 6(1), 79-85. doi:10.1111/j.1365-2036.1992.tb00547.x

DOI
10.1111/j.1365-2036.1992.tb00547.x
Journal article

1991

EFFECT OF AMPICILLIN ON MEFLOQUINE PHARMACOKINETICS IN THAI MALES

KARBWANG, J., BANGCHANG, K. N., BACK, D. J., & BUNNAG, D. (1991). EFFECT OF AMPICILLIN ON MEFLOQUINE PHARMACOKINETICS IN THAI MALES. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 40(6), 631-633. Retrieved from https://www.webofscience.com/

Journal article

UNINTENDED PREGNANCIES AND CONTRACEPTIVE USE

ORME, M., & BACK, D. J. (1991). UNINTENDED PREGNANCIES AND CONTRACEPTIVE USE. BRITISH MEDICAL JOURNAL, 302(6779), 789. Retrieved from https://www.webofscience.com/

Journal article

COMPARATIVE EFFECTS OF THE ANTIMYCOTIC DRUGS KETOCONAZOLE, FLUCONAZOLE, ITRACONAZOLE AND TERBINAFINE ON THE METABOLISM OF CYCLOSPORINE BY HUMAN LIVER-MICROSOMES

BACK, D. J., & TJIA, J. F. (1991). COMPARATIVE EFFECTS OF THE ANTIMYCOTIC DRUGS KETOCONAZOLE, FLUCONAZOLE, ITRACONAZOLE AND TERBINAFINE ON THE METABOLISM OF CYCLOSPORINE BY HUMAN LIVER-MICROSOMES. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 32(5), 624-626. doi:10.1111/j.1365-2125.1991.tb03963.x

DOI
10.1111/j.1365-2125.1991.tb03963.x
Journal article

CYCLOSPORINE METABOLISM BY THE GASTROINTESTINAL MUCOSA

TJIA, J. F., WEBBER, I. R., & BACK, D. J. (1991). CYCLOSPORINE METABOLISM BY THE GASTROINTESTINAL MUCOSA. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 31(3), 344-346. doi:10.1111/j.1365-2125.1991.tb05540.x

DOI
10.1111/j.1365-2125.1991.tb05540.x
Journal article

Concentration of ethinyl estradiol in the serum of 31 young women following a treatment period of 3 months with two low-dose oral contraceptives in an intraindividual cross-over design.

Kuhnz, W., Back, D., Power, J., Schütt, B., & Louton, T. (1991). Concentration of ethinyl estradiol in the serum of 31 young women following a treatment period of 3 months with two low-dose oral contraceptives in an intraindividual cross-over design.. Hormone research, 36(1-2), 63-69. doi:10.1159/000182110

DOI
10.1159/000182110
Journal article

EFFECT OF THE PROGESTOGENS, GESTODENE, 3-KETO DESOGESTREL, LEVONORGESTREL, NORETHISTERONE AND NORGESTIMATE ON THE OXIDATION OF ETHINYLESTRADIOL AND OTHER SUBSTRATES BY HUMAN LIVER-MICROSOMES

BACK, D. J., HOULGRAVE, R., TJIA, J. F., WARD, S., & ORME, M. L. (1991). EFFECT OF THE PROGESTOGENS, GESTODENE, 3-KETO DESOGESTREL, LEVONORGESTREL, NORETHISTERONE AND NORGESTIMATE ON THE OXIDATION OF ETHINYLESTRADIOL AND OTHER SUBSTRATES BY HUMAN LIVER-MICROSOMES. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 38(2), 219-225. doi:10.1016/0960-0760(91)90129-S

DOI
10.1016/0960-0760(91)90129-S
Journal article

METABOLISM OF NORGESTIMATE BY HUMAN GASTROINTESTINAL MUCOSA AND LIVER-MICROSOMES INVITRO

MADDEN, S., & BACK, D. J. (1991). METABOLISM OF NORGESTIMATE BY HUMAN GASTROINTESTINAL MUCOSA AND LIVER-MICROSOMES INVITRO. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 38(4), 497-503. doi:10.1016/0960-0760(91)90338-6

DOI
10.1016/0960-0760(91)90338-6
Journal article

METABOLISM OF THE ORAL-CONTRACEPTIVE STEROIDS ETHYNYLESTRADIOL AND NORGESTIMATE BY NORMAL (HUMA-7) AND MALIGNANT (MCF-7 AND ZR-75-1) HUMAN BREAST CELLS IN CULTURE

WILD, M. J., RUDLAND, P. S., & BACK, D. J. (1991). METABOLISM OF THE ORAL-CONTRACEPTIVE STEROIDS ETHYNYLESTRADIOL AND NORGESTIMATE BY NORMAL (HUMA-7) AND MALIGNANT (MCF-7 AND ZR-75-1) HUMAN BREAST CELLS IN CULTURE. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 39(4), 535-543. doi:10.1016/0960-0760(91)90248-4

DOI
10.1016/0960-0760(91)90248-4
Journal article

Oral contraceptive steroids--pharmacological issues of interest to the prescribing physician.

Orme, M., & Back, D. J. (1991). Oral contraceptive steroids--pharmacological issues of interest to the prescribing physician.. Advances in contraception : the official journal of the Society for the Advancement of Contraception, 7(4), 325-331. doi:10.1007/bf02340178

DOI
10.1007/bf02340178
Journal article

THE EFFECT OF METOCLOPRAMIDE ON MEFLOQUINE PHARMACOKINETICS

BANGCHANG, K. N., KARBWANG, J., BUNNAG, D., HARINASUTA, T., & BACK, D. J. (1991). THE EFFECT OF METOCLOPRAMIDE ON MEFLOQUINE PHARMACOKINETICS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 32(5), 640-641. Retrieved from https://www.webofscience.com/

Journal article

THE EFFECT OF VARIOUS DRUGS ON THE GLUCURONIDATION OF ZIDOVUDINE (AZIDOTHYMIDINE, AZT) BY HUMAN LIVER-MICROSOMES

SIM, S. M., BACK, D. J., & BRECKENRIDGE, A. M. (1991). THE EFFECT OF VARIOUS DRUGS ON THE GLUCURONIDATION OF ZIDOVUDINE (AZIDOTHYMIDINE, AZT) BY HUMAN LIVER-MICROSOMES. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 32(1), 17-21. doi:10.1111/j.1365-2125.1991.tb05607.x

DOI
10.1111/j.1365-2125.1991.tb05607.x
Journal article

THE LACK OF INTERACTION BETWEEN TEMAFLOXACIN AND COMBINED ORAL-CONTRACEPTIVE STEROIDS

BACK, D. J., TJIA, J., MARTIN, C., MILLAR, E., MANT, T., MORRISON, P., & ORME, M. (1991). THE LACK OF INTERACTION BETWEEN TEMAFLOXACIN AND COMBINED ORAL-CONTRACEPTIVE STEROIDS. CONTRACEPTION, 43(4), 317-323. doi:10.1016/0010-7824(91)90070-V

DOI
10.1016/0010-7824(91)90070-V
Journal article

THE PHARMACOKINETICS OF ETHYNYLESTRADIOL IN THE PRESENCE AND ABSENCE OF GESTODENE AND DESOGESTREL

ORME, M., BACK, D. J., WARD, S., & GREEN, S. (1991). THE PHARMACOKINETICS OF ETHYNYLESTRADIOL IN THE PRESENCE AND ABSENCE OF GESTODENE AND DESOGESTREL. CONTRACEPTION, 43(4), 305-316. doi:10.1016/0010-7824(91)90069-R

DOI
10.1016/0010-7824(91)90069-R
Journal article

The interaction between clarithromycin and combined oral-contraceptive steroids

Back, D. J., Tjia, J., Martin, C., Millar, E., Salmon, P., & Orme, M. (1991). The interaction between clarithromycin and combined oral-contraceptive steroids. Journal of Pharmaceutical Medicine, 1(2), 81-87.

Journal article

The lack of interaction between clarithromycin and oral contraceptive steroids

Orme, M., Back, D. J., Tjia, J., Martin, C., Millar, E., & Salmon, P. (1991). The lack of interaction between clarithromycin and oral contraceptive steroids. In British Journal of Clinical Pharmacology Vol. 31.

Conference Paper

The lack of interaction between temafloxacin and oral contraceptive steroids

Orme, M., Back, D. J., Tjia, J., Martin, C., Millar, E., Mant, T., & Morrison, P. (1991). The lack of interaction between temafloxacin and oral contraceptive steroids. In British Journal of Clinical Pharmacology Vol. 31.

Conference Paper

1990

PHARMACOKINETICS OF MEFLOQUINE IN COMBINATION WITH SULFADOXINE PYRIMETHAMINE AND PRIMAQUINE IN MALE THAI PATIENTS WITH FALCIPARUM-MALARIA

KARBWANG, J., BACK, D. J., BUNNAG, D., & BRECKENRIDGE, A. M. (1990). PHARMACOKINETICS OF MEFLOQUINE IN COMBINATION WITH SULFADOXINE PYRIMETHAMINE AND PRIMAQUINE IN MALE THAI PATIENTS WITH FALCIPARUM-MALARIA. BULLETIN OF THE WORLD HEALTH ORGANIZATION, 68(5), 633-638. Retrieved from https://www.webofscience.com/

Journal article

DIFFERENCES IN THE CYTOCHROME-P-450 ISOENZYMES INVOLVED IN THE 2-HYDROXYLATION OF ESTRADIOL AND 17-ALPHA-ETHINYLESTRADIOL - RELATIVE ACTIVITIES OF RAT AND HUMAN LIVER-ENZYMES

BALL, S. E., FORRESTER, L. M., WOLF, C. R., & BACK, D. J. (1990). DIFFERENCES IN THE CYTOCHROME-P-450 ISOENZYMES INVOLVED IN THE 2-HYDROXYLATION OF ESTRADIOL AND 17-ALPHA-ETHINYLESTRADIOL - RELATIVE ACTIVITIES OF RAT AND HUMAN LIVER-ENZYMES. BIOCHEMICAL JOURNAL, 267(1), 221-226. doi:10.1042/bj2670221

DOI
10.1042/bj2670221
Journal article

Azoles and allylamines: the clinical implications of interaction with cytochrome P-450 enzymes

Back, D., & Tija, J. (1990). Azoles and allylamines: the clinical implications of interaction with cytochrome P-450 enzymes. Journal of Dermatological Treatment, 1(sup2), 11-13. doi:10.3109/09546639009089023

DOI
10.3109/09546639009089023
Journal article

Factors affecting the enterohepatic circulation of oral contraceptive steroids.

Orme, M. L., & Back, D. J. (1990). Factors affecting the enterohepatic circulation of oral contraceptive steroids.. American journal of obstetrics and gynecology, 163(6 Pt 2), 2146-2152. doi:10.1016/0002-9378(90)90555-l

DOI
10.1016/0002-9378(90)90555-l
Journal article

Gastrointestinal metabolism of contraceptive steroids.

Back, D. J., Madden, S., & Orme, M. L. (1990). Gastrointestinal metabolism of contraceptive steroids.. American journal of obstetrics and gynecology, 163(6 Pt 2), 2138-2145. doi:10.1016/0002-9378(90)90554-k

DOI
10.1016/0002-9378(90)90554-k
Journal article

METABOLISM OF THE CONTRACEPTIVE STEROID DESOGESTREL BY HUMAN LIVER INVITRO

MADDEN, S., BACK, D. J., & ORME, M. L. (1990). METABOLISM OF THE CONTRACEPTIVE STEROID DESOGESTREL BY HUMAN LIVER INVITRO. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 35(2), 281-288. doi:10.1016/0022-4731(90)90285-Z

DOI
10.1016/0022-4731(90)90285-Z
Journal article

PHARMACOKINETIC DRUG-INTERACTIONS WITH ORAL-CONTRACEPTIVES

BACK, D. J., & ORME, M. L. E. (1990). PHARMACOKINETIC DRUG-INTERACTIONS WITH ORAL-CONTRACEPTIVES. CLINICAL PHARMACOKINETICS, 18(6), 472-484. doi:10.2165/00003088-199018060-00004

DOI
10.2165/00003088-199018060-00004
Journal article

THE INTERACTION OF PHENYTOIN AND CARBAMAZEPINE WITH COMBINED ORAL-CONTRACEPTIVE STEROIDS

CRAWFORD, P., CHADWICK, D. J., MARTIN, C., TJIA, J., BACK, D. J., & ORME, M. (1990). THE INTERACTION OF PHENYTOIN AND CARBAMAZEPINE WITH COMBINED ORAL-CONTRACEPTIVE STEROIDS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 30(6), 892-896. doi:10.1111/j.1365-2125.1990.tb05457.x

DOI
10.1111/j.1365-2125.1990.tb05457.x
Journal article

THE INTERACTION OF PHENYTOIN AND CARBAMAZEPINE WITH ORAL-CONTRACEPTIVE STEROIDS

ORME, M., BACK, D. J., CHADWICK, D. J., CRAWFORD, P., MARTIN, C., & TJIA, J. (1990). THE INTERACTION OF PHENYTOIN AND CARBAMAZEPINE WITH ORAL-CONTRACEPTIVE STEROIDS. In EUROPEAN JOURNAL OF PHARMACOLOGY Vol. 183 (pp. 1029-1030). doi:10.1016/0014-2999(90)92884-L

DOI
10.1016/0014-2999(90)92884-L
Conference Paper

1989

INHIBITION OF ESTROGEN 2-HYDROXYLASE ACTIVITY OF HUMAN-LIVER MICROSOMES BY CIMETIDINE INVITRO - EFFECT OF PREINCUBATION

WILD, M. J., & BACK, D. J. (1989). INHIBITION OF ESTROGEN 2-HYDROXYLASE ACTIVITY OF HUMAN-LIVER MICROSOMES BY CIMETIDINE INVITRO - EFFECT OF PREINCUBATION. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 28(6), P744-P745. Retrieved from https://www.webofscience.com/

Journal article

Cyclosporin metabolites and neurotoxicity.

Trull, A. K., Tan, K. K., Roberts, N. B., Tjia, J. F., & Back, D. J. (1989). Cyclosporin metabolites and neurotoxicity.. Lancet (London, England), 2(8660), 448. doi:10.1016/s0140-6736(89)90626-0

DOI
10.1016/s0140-6736(89)90626-0
Journal article

CALCIUM-CHANNEL ANTAGONISTS AND CYCLOSPORINE METABOLISM - INVITRO STUDIES WITH HUMAN-LIVER MICROSOMES

TJIA, J. F., BACK, D. J., & BRECKENRIDGE, A. M. (1989). CALCIUM-CHANNEL ANTAGONISTS AND CYCLOSPORINE METABOLISM - INVITRO STUDIES WITH HUMAN-LIVER MICROSOMES. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 28(3), 362-365. doi:10.1111/j.1365-2125.1989.tb05439.x

DOI
10.1111/j.1365-2125.1989.tb05439.x
Journal article

COMPARATIVE EFFECTS OF 2 ANTIMYCOTIC AGENTS, KETOCONAZOLE AND TERBINAFINE ON THE METABOLISM OF TOLBUTAMIDE, ETHINYLESTRADIOL, CYCLOSPORINE AND ETHOXYCOUMARIN BY HUMAN-LIVER MICROSOMES INVITRO

BACK, D. J., STEVENSON, P., & TJIA, J. F. (1989). COMPARATIVE EFFECTS OF 2 ANTIMYCOTIC AGENTS, KETOCONAZOLE AND TERBINAFINE ON THE METABOLISM OF TOLBUTAMIDE, ETHINYLESTRADIOL, CYCLOSPORINE AND ETHOXYCOUMARIN BY HUMAN-LIVER MICROSOMES INVITRO. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 28(2), 166-170. doi:10.1111/j.1365-2125.1989.tb05410.x

DOI
10.1111/j.1365-2125.1989.tb05410.x
Journal article

GENETIC-FACTORS INFLUENCING THE METABOLISM OF TOLBUTAMIDE

BACK, D. J., & ORME, M. L. (1989). GENETIC-FACTORS INFLUENCING THE METABOLISM OF TOLBUTAMIDE. PHARMACOLOGY & THERAPEUTICS, 44(2), 147-155. doi:10.1016/0163-7258(89)90064-8

DOI
10.1016/0163-7258(89)90064-8
Journal article

INTERINDIVIDUAL VARIATION IN THE METABOLISM OF ETHYNYLESTRADIOL

ORME, M. L., BACK, D. J., & BALL, S. (1989). INTERINDIVIDUAL VARIATION IN THE METABOLISM OF ETHYNYLESTRADIOL. PHARMACOLOGY & THERAPEUTICS, 43(2), 251-260. doi:10.1016/0163-7258(89)90121-6

DOI
10.1016/0163-7258(89)90121-6
Journal article

Intestinal metabolism of contraceptive steroids in man

Back, D. J., Orme 'E., M. L., & Rogers, S. M. (1989). Intestinal metabolism of contraceptive steroids in man. Progress in Pharmacology and Clinical Pharmacology, 7(2), 289-297.

Journal article

METABOLISM OF THE CONTRACEPTIVE STEROID DESOGESTREL BY THE INTESTINAL-MUCOSA

MADDEN, S., BACK, D. J., MARTIN, C. A., & ORME, M. L. E. (1989). METABOLISM OF THE CONTRACEPTIVE STEROID DESOGESTREL BY THE INTESTINAL-MUCOSA. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 27(3), 295-299. doi:10.1111/j.1365-2125.1989.tb05368.x

DOI
10.1111/j.1365-2125.1989.tb05368.x
Journal article

METABOLISM OF THE CONTRACEPTIVE STEROID NORGESTIMATE BY HUMAN GUT AND LIVER INVITRO

MADDEN, S., & BACK, D. J. (1989). METABOLISM OF THE CONTRACEPTIVE STEROID NORGESTIMATE BY HUMAN GUT AND LIVER INVITRO. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 28(6), P743-P744. Retrieved from https://www.webofscience.com/

Journal article

The use of Ussing chambers for the study of intestinal metabolism in vitro

Rogers, S. M., & Back, D. J. (1989). The use of Ussing chambers for the study of intestinal metabolism in vitro. Progress in Pharmacology and Clinical Pharmacology, 7(2), 43-53.

Journal article

1988

EFFECT OF ORAL-CONTRACEPTIVE STEROIDS ON THE CLINICAL COURSE OF MALARIA INFECTION AND ON THE PHARMACOKINETICS OF MEFLOQUINE IN THAI WOMEN

KARBWANG, J., LOOAREESUWAN, S., BACK, D. J., MIGASANA, S., BUNNAG, D., & BRECKENRIDGE, A. M. (1988). EFFECT OF ORAL-CONTRACEPTIVE STEROIDS ON THE CLINICAL COURSE OF MALARIA INFECTION AND ON THE PHARMACOKINETICS OF MEFLOQUINE IN THAI WOMEN. BULLETIN OF THE WORLD HEALTH ORGANIZATION, 66(6), 763-767. Retrieved from https://www.webofscience.com/

Journal article

SULFATION AND GLUCURONIDATION OF PARACETAMOL IN HUMAN-LIVER - ASSAY CONDITIONS

PACIFICI, G. M., BACK, D. J., & ORME, M. L. (1988). SULFATION AND GLUCURONIDATION OF PARACETAMOL IN HUMAN-LIVER - ASSAY CONDITIONS. BIOCHEMICAL PHARMACOLOGY, 37(22), 4405-4407. doi:10.1016/0006-2952(88)90624-7

DOI
10.1016/0006-2952(88)90624-7
Journal article

A COMPARISON OF THE PHARMACOKINETICS OF MEFLOQUINE IN HEALTHY THAI VOLUNTEERS AND IN THAI PATIENTS WITH FALCIPARUM-MALARIA

KARBWANG, J., BACK, D. J., BUNNAG, D., & BRECKENRIDGE, A. M. (1988). A COMPARISON OF THE PHARMACOKINETICS OF MEFLOQUINE IN HEALTHY THAI VOLUNTEERS AND IN THAI PATIENTS WITH FALCIPARUM-MALARIA. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 35(6), 677-680. doi:10.1007/BF00637607

DOI
10.1007/BF00637607
Journal article

SELECTIVE-INHIBITION OF DRUG OXIDATION AFTER SIMULTANEOUS ADMINISTRATION OF 2 PROBE DRUGS, ANTIPYRINE AND TOLBUTAMIDE

BACK, D. J., TJIA, J., MONIG, H., OHNHAUS, E. E., & PARK, B. K. (1988). SELECTIVE-INHIBITION OF DRUG OXIDATION AFTER SIMULTANEOUS ADMINISTRATION OF 2 PROBE DRUGS, ANTIPYRINE AND TOLBUTAMIDE. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 34(2), 157-163. doi:10.1007/BF00614553

DOI
10.1007/BF00614553
Journal article

CHARACTERIZATION AND INHIBITION OF ESTROGEN 2-HYDROXYLASE ACTIVITY IN HUMAN-LIVER MICROSOMES

BALL, S., BACK, D. J., & ORME, M. L. E. (1988). CHARACTERIZATION AND INHIBITION OF ESTROGEN 2-HYDROXYLASE ACTIVITY IN HUMAN-LIVER MICROSOMES. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 25(5), P643-P644. Retrieved from https://www.webofscience.com/

Journal article

EVALUATION OF COMMITTEE ON SAFETY OF MEDICINES YELLOW CARD REPORTS ON ORAL CONTRACEPTIVE DRUG INTERACTIONS WITH ANTI-CONVULSANTS AND ANTIBIOTICS

BACK, D. J., GRIMMER, S. F. M., ORME, M. L. E., PROUDLOVE, C., MANN, R. D., & BRECKENRIDGE, A. M. (1988). EVALUATION OF COMMITTEE ON SAFETY OF MEDICINES YELLOW CARD REPORTS ON ORAL CONTRACEPTIVE DRUG INTERACTIONS WITH ANTI-CONVULSANTS AND ANTIBIOTICS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 25(5), 527-532. doi:10.1111/j.1365-2125.1988.tb03341.x

DOI
10.1111/j.1365-2125.1988.tb03341.x
Journal article

Inhibition of tolbutamide metabolism by antimalarial drugs.

Karbwang, J., Back, D. J., Bunnag, D., & Breckenridge, A. M. (1988). Inhibition of tolbutamide metabolism by antimalarial drugs.. The Southeast Asian journal of tropical medicine and public health, 19(2), 235-241.

Journal article

PRE-SYSTEMIC METABOLISM OF THE ORAL-CONTRACEPTIVE STEROID DESOGESTREL

BACK, D. J., MADDEN, S., & MARTIN, C. A. (1988). PRE-SYSTEMIC METABOLISM OF THE ORAL-CONTRACEPTIVE STEROID DESOGESTREL. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 25(5), P675-P676. Retrieved from https://www.webofscience.com/

Journal article

SULFATION AND GLUCURONIDATION OF ETHINYLESTRADIOL IN HUMAN-LIVER INVITRO

PACIFICI, G. M., & BACK, D. J. (1988). SULFATION AND GLUCURONIDATION OF ETHINYLESTRADIOL IN HUMAN-LIVER INVITRO. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 31(3), 345-349. doi:10.1016/0022-4731(88)90360-3

DOI
10.1016/0022-4731(88)90360-3
Journal article

1987

Inhibition of theophylline metabolism by interferon.

Winstanley, P. A., Back, D. J., & Breckenridge, A. M. (1987). Inhibition of theophylline metabolism by interferon.. Lancet (London, England), 2(8571), 1340. doi:10.1016/s0140-6736(87)91240-2

DOI
10.1016/s0140-6736(87)91240-2
Journal article

SINGLE DOSE PRIMAQUINE HAS NO EFFECT ON PARACETAMOL CLEARANCE

BACK, D. J., & TJIA, J. F. (1987). SINGLE DOSE PRIMAQUINE HAS NO EFFECT ON PARACETAMOL CLEARANCE. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 32(2), 203-205. doi:10.1007/BF00542197

DOI
10.1007/BF00542197
Journal article

THE PHARMACOKINETICS OF MEFLOQUINE WHEN GIVEN ALONE OR IN COMBINATION WITH SULFADOXINE AND PYRIMETHAMINE IN THAI MALE AND FEMALE SUBJECTS

KARBWANG, J., BUNNAG, D., BRECKENRIDGE, A. M., & BACK, D. J. (1987). THE PHARMACOKINETICS OF MEFLOQUINE WHEN GIVEN ALONE OR IN COMBINATION WITH SULFADOXINE AND PYRIMETHAMINE IN THAI MALE AND FEMALE SUBJECTS. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 32(2), 173-177. doi:10.1007/BF00542191

DOI
10.1007/BF00542191
Journal article

COMPARATIVE PHARMACOKINETICS OF LEVONORGESTREL AND ETHINYLESTRADIOL FOLLOWING INTRAVENOUS, ORAL AND VAGINAL ADMINISTRATION

BACK, D. J., GRIMMER, S. F. M., ROGERS, S., STEVENSON, P. J., & ORME, M. L. B. (1987). COMPARATIVE PHARMACOKINETICS OF LEVONORGESTREL AND ETHINYLESTRADIOL FOLLOWING INTRAVENOUS, ORAL AND VAGINAL ADMINISTRATION. CONTRACEPTION, 36(4), 471-479. doi:10.1016/0010-7824(87)90095-3

DOI
10.1016/0010-7824(87)90095-3
Journal article

INTESTINAL METABOLISM OF ETHINYLESTRADIOL AND PARACETAMOL INVITRO - STUDIES USING USSING CHAMBERS

ROGERS, S. M., BACK, D. J., & ORME, M. L. (1987). INTESTINAL METABOLISM OF ETHINYLESTRADIOL AND PARACETAMOL INVITRO - STUDIES USING USSING CHAMBERS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 23(6), 727-734. doi:10.1111/j.1365-2125.1987.tb03108.x

DOI
10.1111/j.1365-2125.1987.tb03108.x
Journal article

PARACETAMOL INTERACTION WITH ORAL-CONTRACEPTIVE STEROIDS - INCREASED PLASMA-CONCENTRATIONS OF ETHINYLESTRADIOL

ROGERS, S. M., BACK, D. J., STEVENSON, P. J., GRIMMER, S. F. M., & ORME, M. L. (1987). PARACETAMOL INTERACTION WITH ORAL-CONTRACEPTIVE STEROIDS - INCREASED PLASMA-CONCENTRATIONS OF ETHINYLESTRADIOL. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 23(6), 721-725. doi:10.1111/j.1365-2125.1987.tb03107.x

DOI
10.1111/j.1365-2125.1987.tb03107.x
Journal article

PHARMACOKINETICS OF CONTRACEPTIVE STEROIDS IN PATIENTS WITH CYSTIC-FIBROSIS

STEAD, R. J., GRIMMER, S. F. M., ROGERS, S. M., BACK, D. J., ORME, M. L. E., HODSON, M. E., & BATTEN, J. C. (1987). PHARMACOKINETICS OF CONTRACEPTIVE STEROIDS IN PATIENTS WITH CYSTIC-FIBROSIS. THORAX, 42(1), 59-64. doi:10.1136/thx.42.1.59

DOI
10.1136/thx.42.1.59
Journal article

PLASMA AND WHOLE-BLOOD MEFLOQUINE CONCENTRATIONS DURING TREATMENT OF CHLOROQUINE-RESISTANT FALCIPARUM-MALARIA WITH THE COMBINATION MEFLOQUINE-SULFADOXINE-PYRIMETHAMINE

KARBWANG, J., LOOAREESUWAN, S., PHILLIPS, R. E., WATTANAGOON, Y., MOLYNEUX, M. E., NAGACHINTA, B., . . . WARRELL, D. A. (1987). PLASMA AND WHOLE-BLOOD MEFLOQUINE CONCENTRATIONS DURING TREATMENT OF CHLOROQUINE-RESISTANT FALCIPARUM-MALARIA WITH THE COMBINATION MEFLOQUINE-SULFADOXINE-PYRIMETHAMINE. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 23(4), 477-481. doi:10.1111/j.1365-2125.1987.tb03079.x

DOI
10.1111/j.1365-2125.1987.tb03079.x
Journal article

PLASMA-CONCENTRATIONS OF 3-KETO-DESOGESTREL AFTER ORAL-ADMINISTRATION OF DESOGESTREL AND INTRAVENOUS ADMINISTRATION OF 3-KETO-DESOGESTREL

BACK, D. J., GRIMMER, S. F. M., SHENOY, N., & ORME, M. L. E. (1987). PLASMA-CONCENTRATIONS OF 3-KETO-DESOGESTREL AFTER ORAL-ADMINISTRATION OF DESOGESTREL AND INTRAVENOUS ADMINISTRATION OF 3-KETO-DESOGESTREL. CONTRACEPTION, 35(6), 619-626. doi:10.1016/S0010-7824(87)80021-5

DOI
10.1016/S0010-7824(87)80021-5
Journal article

Review: first-pass metabolism by the gastrointestinal mucosa.

Back, D. J., & Rogers, S. M. (1987). Review: first-pass metabolism by the gastrointestinal mucosa.. Alimentary pharmacology & therapeutics, 1(5), 339-357. doi:10.1111/j.1365-2036.1987.tb00634.x

DOI
10.1111/j.1365-2036.1987.tb00634.x
Journal article

THE METABOLISM OF 17 ALPHA-ETHINYLESTRADIOL BY HUMAN-LIVER MICROSOMES - FORMATION OF CATECHOL AND CHEMICALLY REACTIVE METABOLITES

PURBA, H. S., MAGGS, J. L., ORME, M. L. E., BACK, D. J., & PARK, B. K. (1987). THE METABOLISM OF 17 ALPHA-ETHINYLESTRADIOL BY HUMAN-LIVER MICROSOMES - FORMATION OF CATECHOL AND CHEMICALLY REACTIVE METABOLITES. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 23(4), 447-453. doi:10.1111/j.1365-2125.1987.tb03074.x

DOI
10.1111/j.1365-2125.1987.tb03074.x
Journal article

THE RELATIVE BIOAVAILABILITY OF LEVONORGESTREL AND ETHINYLESTRADIOL WHEN ADMINISTERED IN TABLET AND CAPSULE FORM

BACK, D. J., KILLICK, S. R., STEVENSON, P. J., SHENOY, N., ELSTEIN, M., & COHEN, M. (1987). THE RELATIVE BIOAVAILABILITY OF LEVONORGESTREL AND ETHINYLESTRADIOL WHEN ADMINISTERED IN TABLET AND CAPSULE FORM. CONTRACEPTION, 36(3), 321-326. doi:10.1016/0010-7824(87)90102-8

DOI
10.1016/0010-7824(87)90102-8
Journal article

TOLBUTAMIDE 4-HYDROXYLASE ACTIVITY OF HUMAN-LIVER MICROSOMES - EFFECT OF INHIBITORS

PURBA, H. S., BACK, D. J., & ORME, M. L. (1987). TOLBUTAMIDE 4-HYDROXYLASE ACTIVITY OF HUMAN-LIVER MICROSOMES - EFFECT OF INHIBITORS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 24(2), 230-234. doi:10.1111/j.1365-2125.1987.tb03167.x

DOI
10.1111/j.1365-2125.1987.tb03167.x
Journal article

1986

USE OF ORAL-CONTRACEPTIVES BY WOMEN WITH EPILEPSY

ORME, M., BACK, D. J., & GUILLEBAUD, J. (1986). USE OF ORAL-CONTRACEPTIVES BY WOMEN WITH EPILEPSY. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 256(21), 2962. doi:10.1001/jama.1986.03380210057019

DOI
10.1001/jama.1986.03380210057019
Journal article

INHIBITION OF ETHINYLESTRADIOL AND TOLBUTAMIDE METABOLISM BY QUINOLINE DERIVATIVES INVITRO

RIVIERE, J. H., & BACK, D. J. (1986). INHIBITION OF ETHINYLESTRADIOL AND TOLBUTAMIDE METABOLISM BY QUINOLINE DERIVATIVES INVITRO. CHEMICO-BIOLOGICAL INTERACTIONS, 59(3), 301-308. doi:10.1016/S0009-2797(86)80075-8

DOI
10.1016/S0009-2797(86)80075-8
Journal article

DRUG-INTERACTIONS BETWEEN ORAL-CONTRACEPTIVE STEROIDS AND ANTIBIOTICS

ORME, M. L., & BACK, D. J. (1986). DRUG-INTERACTIONS BETWEEN ORAL-CONTRACEPTIVE STEROIDS AND ANTIBIOTICS. BRITISH DENTAL JOURNAL, 160(5), 169-170. doi:10.1038/sj.bdj.4805798

DOI
10.1038/sj.bdj.4805798
Journal article

CONTRACEPTIVE STEROID CONCENTRATIONS IN WOMEN WITH EARLY ACTIVE SCHISTOSOMIASIS - LACK OF EFFECT OF ANTISCHISTOSOMAL DRUGS

ELRAGHY, I., BACK, D. J., OSMAN, F., ORME, M. L., & FATHALLA, M. (1986). CONTRACEPTIVE STEROID CONCENTRATIONS IN WOMEN WITH EARLY ACTIVE SCHISTOSOMIASIS - LACK OF EFFECT OF ANTISCHISTOSOMAL DRUGS. CONTRACEPTION, 33(4), 373-377. doi:10.1016/0010-7824(86)90099-5

DOI
10.1016/0010-7824(86)90099-5
Journal article

INHIBITION OF ESTROGEN 2-HYDROXYLASE

PURBA, H. S., BACK, D. J., & BRECKENRIDGE, A. M. (1986). INHIBITION OF ESTROGEN 2-HYDROXYLASE. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 24(5), 1091-1093. doi:10.1016/0022-4731(86)90365-1

DOI
10.1016/0022-4731(86)90365-1
Journal article

INTERACTIONS BETWEEN ORAL-CONTRACEPTIVE STEROIDS AND BROAD-SPECTRUM ANTIBIOTICS

ORME, M. L., & BACK, D. J. (1986). INTERACTIONS BETWEEN ORAL-CONTRACEPTIVE STEROIDS AND BROAD-SPECTRUM ANTIBIOTICS. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 11(4), 327-331. doi:10.1111/j.1365-2230.1986.tb00471.x

DOI
10.1111/j.1365-2230.1986.tb00471.x
Journal article

INTESTINAL-ABSORPTION OF ESTRONE, ESTRONE GLUCURONIDE AND ESTRONE SULFATE IN THE RAT INSITU .2. STUDIES WITH THE DOLUISIO TECHNIQUE

SIM, S. M., & BACK, D. J. (1986). INTESTINAL-ABSORPTION OF ESTRONE, ESTRONE GLUCURONIDE AND ESTRONE SULFATE IN THE RAT INSITU .2. STUDIES WITH THE DOLUISIO TECHNIQUE. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 24(5), 1085-1089. Retrieved from https://www.webofscience.com/

Journal article

PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS IN EGYPTIAN WOMEN - STUDIES WITH OVRAL, NORDETTE AND NORMINEST

ELRAGHY, I., BACK, D. J., MAKERAM, M., SALEM, H., OSMAN, F., FATHALLA, M., & ORME, M. L. (1986). PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS IN EGYPTIAN WOMEN - STUDIES WITH OVRAL, NORDETTE AND NORMINEST. CONTRACEPTION, 33(4), 379-384. doi:10.1016/0010-7824(86)90100-9

DOI
10.1016/0010-7824(86)90100-9
Journal article

THE BIOAVAILABILITY OF ETHINYLESTRADIOL AND LEVONORGESTREL IN PATIENTS WITH AN ILEOSTOMY

GRIMMER, S. F. M., BACK, D. J., ORME, M. L., COWIE, A., GILMORE, I., & TJIA, J. (1986). THE BIOAVAILABILITY OF ETHINYLESTRADIOL AND LEVONORGESTREL IN PATIENTS WITH AN ILEOSTOMY. CONTRACEPTION, 33(1), 51-59. doi:10.1016/0010-7824(86)90032-6

DOI
10.1016/0010-7824(86)90032-6
Journal article

THE LACK OF EFFECT OF SODIUM VALPROATE ON THE PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS

CRAWFORD, P., CHADWICK, D., CLELAND, P., TJIA, J., COWIE, A., BACK, D. J., & ORME, M. L. (1986). THE LACK OF EFFECT OF SODIUM VALPROATE ON THE PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS. CONTRACEPTION, 33(1), 23-29. doi:10.1016/0010-7824(86)90028-4

DOI
10.1016/0010-7824(86)90028-4
Journal article

1985

EFFECT OF MEFLOQUINE ON HEPATIC DRUG-METABOLISM IN THE RAT - COMPARATIVE-STUDY WITH PRIMAQUINE

RIVIERE, J. H., & BACK, D. J. (1985). EFFECT OF MEFLOQUINE ON HEPATIC DRUG-METABOLISM IN THE RAT - COMPARATIVE-STUDY WITH PRIMAQUINE. BIOCHEMICAL PHARMACOLOGY, 34(4), 567-571. doi:10.1016/0006-2952(85)90191-1

DOI
10.1016/0006-2952(85)90191-1
Journal article

A NON-CHROMATOGRAPHIC RADIOIMMUNOASSAY FOR 3-OXO DESOGESTREL

SHAW, M. A., BACK, D. J., COWIE, A. M., & ORME, M. C. L. (1985). A NON-CHROMATOGRAPHIC RADIOIMMUNOASSAY FOR 3-OXO DESOGESTREL. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 22(1), 111-113. doi:10.1016/0022-4731(85)90149-9

DOI
10.1016/0022-4731(85)90149-9
Journal article

INHIBITION OF TOLBUTAMIDE METABOLISM BY SUBSTITUTED IMIDAZOLE DRUGS INVIVO - EVIDENCE FOR A STRUCTURE-ACTIVITY RELATIONSHIP

BACK, D. J., & TJIA, J. F. (1985). INHIBITION OF TOLBUTAMIDE METABOLISM BY SUBSTITUTED IMIDAZOLE DRUGS INVIVO - EVIDENCE FOR A STRUCTURE-ACTIVITY RELATIONSHIP. BRITISH JOURNAL OF PHARMACOLOGY, 85(1), 121-126. doi:10.1111/j.1476-5381.1985.tb08838.x

DOI
10.1111/j.1476-5381.1985.tb08838.x
Journal article

INTESTINAL-ABSORPTION OF ESTRONE, ESTRONE GLUCURONIDE AND ESTRONE SULFATE IN THE RAT INSITU .1. IMPORTANCE OF HYDROLYTIC ENZYMES ON CONJUGATE ABSORPTION

SIM, S. M., & BACK, D. J. (1985). INTESTINAL-ABSORPTION OF ESTRONE, ESTRONE GLUCURONIDE AND ESTRONE SULFATE IN THE RAT INSITU .1. IMPORTANCE OF HYDROLYTIC ENZYMES ON CONJUGATE ABSORPTION. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 22(6), 781-788. Retrieved from https://www.webofscience.com/

Journal article

LACK OF EFFECT OF HIGHLY PURIFIED SUBUNIT INFLUENZA VACCINATION ON THEOPHYLLINE METABOLISM

WINSTANLEY, P. A., TJIA, J., BACK, D. J., HOBSON, D., & BRECKENRIDGE, A. M. (1985). LACK OF EFFECT OF HIGHLY PURIFIED SUBUNIT INFLUENZA VACCINATION ON THEOPHYLLINE METABOLISM. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 20(1), 47-53. doi:10.1111/j.1365-2125.1985.tb02797.x

DOI
10.1111/j.1365-2125.1985.tb02797.x
Journal article

NORETHISTERONE CONCENTRATION IN BREAST-MILK AND INFANT AND MATERNAL PLASMA DURING ETHYNODIOL DIACETATE ADMINISTRATION

COOKE, I. D., BACK, D. J., & SHROFF, N. E. (1985). NORETHISTERONE CONCENTRATION IN BREAST-MILK AND INFANT AND MATERNAL PLASMA DURING ETHYNODIOL DIACETATE ADMINISTRATION. CONTRACEPTION, 31(6), 611-621. doi:10.1016/0010-7824(85)90061-7

DOI
10.1016/0010-7824(85)90061-7
Journal article

THE EFFECT OF SOME BENZIMIDAZOLES ON THE DISPOSITION OF ANTIPYRINE AND TOLBUTAMIDE FROM THE RAT ISOLATED PERFUSED LIVER

WARD, S. A., MIHALY, G. W., TJIA, J. F., & BACK, D. J. (1985). THE EFFECT OF SOME BENZIMIDAZOLES ON THE DISPOSITION OF ANTIPYRINE AND TOLBUTAMIDE FROM THE RAT ISOLATED PERFUSED LIVER. JOURNAL OF PHARMACY AND PHARMACOLOGY, 37(1), 62-64. doi:10.1111/j.2042-7158.1985.tb04934.x

DOI
10.1111/j.2042-7158.1985.tb04934.x
Journal article

THE PHARMACOKINETICS OF ANTIPYRINE IN PATIENTS WITH GRADED SEVERITY OF SCHISTOSOMIASIS

ELRAGHY, I., BACK, D. J., OSMAN, F., NAFEH, M. A., & ORME, M. L. (1985). THE PHARMACOKINETICS OF ANTIPYRINE IN PATIENTS WITH GRADED SEVERITY OF SCHISTOSOMIASIS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 20(4), 313-316. doi:10.1111/j.1365-2125.1985.tb05069.x

DOI
10.1111/j.1365-2125.1985.tb05069.x
Journal article

THE PHARMACOKINETICS OF MEFLOQUINE IN MAN - LACK OF EFFECT OF MEFLOQUINE ON ANTIPYRINE METABOLISM

RIVIERE, J. H., BACK, D. J., BRECKENRIDGE, A. M., & HOWELLS, R. E. (1985). THE PHARMACOKINETICS OF MEFLOQUINE IN MAN - LACK OF EFFECT OF MEFLOQUINE ON ANTIPYRINE METABOLISM. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 20(5), 469-474. doi:10.1111/j.1365-2125.1985.tb05099.x

DOI
10.1111/j.1365-2125.1985.tb05099.x
Journal article

1984

Isotretinoin and contraception.

Orme, M., Back, D. J., Shaw, M. A., Allen, W. L., Tjia, J., Cunliffe, W. J., & Jones, D. H. (1984). Isotretinoin and contraception.. Lancet (London, England), 2(8405), 752-753. doi:10.1016/s0140-6736(84)92659-x

DOI
10.1016/s0140-6736(84)92659-x
Journal article

AN INVESTIGATION OF THE EFFECTS OF PHENOBARBITONE ON THE PHARMACOKINETICS OF NORETHINDRONE IN THE RAT USING LIVER PERFUSION AND EVERTED GUT SACS

BACK, D. J., MACNEE, C. M., ORME, M. L., ROWE, P. H., & SMITH, E. (1984). AN INVESTIGATION OF THE EFFECTS OF PHENOBARBITONE ON THE PHARMACOKINETICS OF NORETHINDRONE IN THE RAT USING LIVER PERFUSION AND EVERTED GUT SACS. BIOCHEMICAL PHARMACOLOGY, 33(10), 1595-1600. doi:10.1016/0006-2952(84)90279-X

DOI
10.1016/0006-2952(84)90279-X
Journal article

OVERESTIMATION OF LOW PROGESTERONE CONCENTRATIONS BY A COMMERCIAL RADIOIMMUNOASSAY KIT

ALLEN, W. L., BACK, D. J., & SHAW, M. A. (1984). OVERESTIMATION OF LOW PROGESTERONE CONCENTRATIONS BY A COMMERCIAL RADIOIMMUNOASSAY KIT. CLINICAL CHEMISTRY, 30(3), 495-496. Retrieved from https://www.webofscience.com/

Journal article

DRUG-METABOLISM AND TROPICAL DISEASE

BRECKENRIDGE, A., AWADZI, K., BACK, D. J., EDWARDS, G., GILLES, H., ORME, M., & WARD, S. (1984). DRUG-METABOLISM AND TROPICAL DISEASE. BIOCHEMICAL SOCIETY TRANSACTIONS, 12(1), 90-95. doi:10.1042/bst0120090

DOI
10.1042/bst0120090
Journal article

Pharmacokinetic and "potency" of contraceptive steroids.

Back, D. J., Breckenridge, A., Orme, M., & Shaw, M. A. (1984). Pharmacokinetic and "potency" of contraceptive steroids.. Lancet (London, England), 1(8369), 171. doi:10.1016/s0140-6736(84)90113-2

DOI
10.1016/s0140-6736(84)90113-2
Journal article

2-HYDROXYLATION OF ETHINYLESTRADIOL IN RELATION TO THE OXIDATION OF SPARTEINE AND ANTIPYRINE

BACK, D. J., MAGGS, J. L., PURBA, H. S., NEWBY, S., & PARK, B. K. (1984). 2-HYDROXYLATION OF ETHINYLESTRADIOL IN RELATION TO THE OXIDATION OF SPARTEINE AND ANTIPYRINE. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 18(4), 603-607. doi:10.1111/j.1365-2125.1984.tb02511.x

DOI
10.1111/j.1365-2125.1984.tb02511.x
Journal article

DISTRIBUTION OF ESTRONE SULFATASE ACTIVITY IN THE INTESTINE OF GERMFREE AND CONVENTIONAL RATS

HUIJGHEBAERT, S. M., SIM, S. M., BACK, D. J., & EYSSEN, H. J. (1984). DISTRIBUTION OF ESTRONE SULFATASE ACTIVITY IN THE INTESTINE OF GERMFREE AND CONVENTIONAL RATS. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 20(5), 1175-1179. doi:10.1016/0022-4731(84)90363-7

DOI
10.1016/0022-4731(84)90363-7
Journal article

INHIBITION OF HEPATIC-MICROSOMAL ENZYMES BY GOSSYPOL IN THE RAT

MA, X. N., & BACK, D. J. (1984). INHIBITION OF HEPATIC-MICROSOMAL ENZYMES BY GOSSYPOL IN THE RAT. CONTRACEPTION, 30(1), 89-97. Retrieved from https://www.webofscience.com/

Journal article

INTERINDIVIDUAL VARIABILITY IN ORAL-CONTRACEPTIVE DISPOSITION

BACK, D. J., & ORME, M. L. (1984). INTERINDIVIDUAL VARIABILITY IN ORAL-CONTRACEPTIVE DISPOSITION. TRENDS IN PHARMACOLOGICAL SCIENCES, 5(11), 480-483. doi:10.1016/0165-6147(84)90514-5

DOI
10.1016/0165-6147(84)90514-5
Journal article

PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS FOLLOWING THE ADMINISTRATION OF THE ANTIMALARIAL-DRUGS PRIMAQUINE AND CHLOROQUINE

BACK, D. J., BRECKENRIDGE, A. M., GRIMMER, S. F. M., ORME, M. L. E., & PURBA, H. S. (1984). PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS FOLLOWING THE ADMINISTRATION OF THE ANTIMALARIAL-DRUGS PRIMAQUINE AND CHLOROQUINE. CONTRACEPTION, 30(3), 289-295. doi:10.1016/0010-7824(84)90092-1

DOI
10.1016/0010-7824(84)90092-1
Journal article

TOLBUTAMIDE AS A MODEL-DRUG FOR THE STUDY OF ENZYME-INDUCTION AND ENZYME-INHIBITION IN THE RAT

BACK, D. J., SUTCLIFFE, F., & TJIA, J. F. (1984). TOLBUTAMIDE AS A MODEL-DRUG FOR THE STUDY OF ENZYME-INDUCTION AND ENZYME-INHIBITION IN THE RAT. BRITISH JOURNAL OF PHARMACOLOGY, 81(3), 557-562. doi:10.1111/j.1476-5381.1984.tb10109.x

DOI
10.1111/j.1476-5381.1984.tb10109.x
Journal article

1983

POTENTIAL PROBLEMS WITH AQUEOUS STEROID SOLUTIONS

SIM, S. M., BACK, D. J., & TJIA, J. F. (1983). POTENTIAL PROBLEMS WITH AQUEOUS STEROID SOLUTIONS. JOURNAL OF PHARMACY AND PHARMACOLOGY, 35(3), 200. doi:10.1111/j.2042-7158.1983.tb04312.x

DOI
10.1111/j.2042-7158.1983.tb04312.x
Journal article

Drug interactions with oral contraceptive steroids.

Back, D. J., Breckenridge, A. M., & Orme, M. L. (1983). Drug interactions with oral contraceptive steroids.. IPPF medical bulletin, 17(1), 1-2.

Journal article

INHIBITION OF DRUG-METABOLISM BY THE ANTI-MALARIAL DRUGS CHLOROQUINE AND PRIMAQUINE IN THE RAT

BACK, D. J., PURBA, H. S., STAIGER, C., ORME, M. L., & BRECKENRIDGE, A. M. (1983). INHIBITION OF DRUG-METABOLISM BY THE ANTI-MALARIAL DRUGS CHLOROQUINE AND PRIMAQUINE IN THE RAT. BIOCHEMICAL PHARMACOLOGY, 32(2), 257-263. doi:10.1016/0006-2952(83)90553-1

DOI
10.1016/0006-2952(83)90553-1
Journal article

ADSORPTION OF PREGNANEDIOL 3-ALPHA-GLUCURONIDE BY PLASTICS AND GLASS

SHAW, M. A., & BACK, D. J. (1983). ADSORPTION OF PREGNANEDIOL 3-ALPHA-GLUCURONIDE BY PLASTICS AND GLASS. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 19(5), 1681-1682. doi:10.1016/0022-4731(83)90391-6

DOI
10.1016/0022-4731(83)90391-6
Journal article

CLINICAL PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS

ORME, M. L., BACK, D. J., & BRECKENRIDGE, A. M. (1983). CLINICAL PHARMACOKINETICS OF ORAL-CONTRACEPTIVE STEROIDS. CLINICAL PHARMACOKINETICS, 8(2), 95-136. doi:10.2165/00003088-198308020-00001

DOI
10.2165/00003088-198308020-00001
Journal article

EFFECT OF CHLOROQUINE AND PRIMAQUINE ON ANTIPYRINE METABOLISM

BACK, D. J., PURBA, H. S., PARK, B. K., WARD, S. A., & ORME, M. L. (1983). EFFECT OF CHLOROQUINE AND PRIMAQUINE ON ANTIPYRINE METABOLISM. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 16(5), 497-502. doi:10.1111/j.1365-2125.1983.tb02206.x

DOI
10.1111/j.1365-2125.1983.tb02206.x
Journal article

GASTROINTESTINAL ABSORPTION OF ESTRONE SULFATE IN GERMFREE AND CONVENTIONAL RATS

SIM, S. M., HUIJGHEBAERT, S., BACK, D. J., & EYSSEN, H. J. (1983). GASTROINTESTINAL ABSORPTION OF ESTRONE SULFATE IN GERMFREE AND CONVENTIONAL RATS. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 18(4), 499-503. Retrieved from https://www.webofscience.com/

Journal article

ORAL-CONTRACEPTIVES AND ASCORBIC-ACID METABOLISM

BACK, D. J., & EORME, M. L. (1983). ORAL-CONTRACEPTIVES AND ASCORBIC-ACID METABOLISM. AMERICAN JOURNAL OF CLINICAL NUTRITION, 37(2), 330. doi:10.1093/ajcn/37.2.330

DOI
10.1093/ajcn/37.2.330
Journal article

Potential problems with aqueous steroid solutions.

Sim, S. M., Back, D. J., & Tjia, J. F. (1983). Potential problems with aqueous steroid solutions.. The Journal of pharmacy and pharmacology, 35(3), 200. doi:10.1111/j.2042-7158.1983.tb04312.x

DOI
10.1111/j.2042-7158.1983.tb04312.x
Journal article

Sulphaphenazole and drug oxidation in man.

Back, D. B., Park, B. K., Tjia, J. F., & Newby, S. N. (1983). Sulphaphenazole and drug oxidation in man.. British journal of clinical pharmacology, 16(4), 460-461. doi:10.1111/j.1365-2125.1983.tb02199.x

DOI
10.1111/j.1365-2125.1983.tb02199.x
Journal article

THE EFFECT OF CO-TRIMOXAZOLE ON ORAL-CONTRACEPTIVE STEROIDS IN WOMEN

GRIMMER, S. F. M., ALLEN, W. L., BACK, D. J., BRECKENRIDGE, A. M., ORME, M., & TJIA, J. (1983). THE EFFECT OF CO-TRIMOXAZOLE ON ORAL-CONTRACEPTIVE STEROIDS IN WOMEN. CONTRACEPTION, 28(1), 53-59. doi:10.1016/S0010-7824(83)80005-5

DOI
10.1016/S0010-7824(83)80005-5
Journal article

URINARY CONCENTRATIONS OF STEROID GLUCURONIDES IN WOMEN TAKING ORAL-CONTRACEPTIVES

SHAW, M. A., BACK, D. J., AIRD, S. A., GRIMMER, S. F. M., & ORME, M. C. L. (1983). URINARY CONCENTRATIONS OF STEROID GLUCURONIDES IN WOMEN TAKING ORAL-CONTRACEPTIVES. CONTRACEPTION, 28(1), 69-75. doi:10.1016/S0010-7824(83)80007-9

DOI
10.1016/S0010-7824(83)80007-9
Journal article

1982

AN ANTIBIOTIC INTERACTION WITH ETHINYLESTRADIOL IN THE RAT AND RABBIT

BACK, D. J., BRECKENRIDGE, A. M., CROSS, K. J., ORME, M. L., & THOMAS, E. (1982). AN ANTIBIOTIC INTERACTION WITH ETHINYLESTRADIOL IN THE RAT AND RABBIT. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 16(3), 407-413. doi:10.1016/0022-4731(82)90053-X

DOI
10.1016/0022-4731(82)90053-X
Journal article

INTERACTION BETWEEN ETHINYLESTRADIOL AND ASCORBIC-ACID

BACK, D. J., BRECKENRIDGE, A. M., MACIVER, M., ORME, M. L., PURBA, H., & ROWE, P. H. (1982). INTERACTION BETWEEN ETHINYLESTRADIOL AND ASCORBIC-ACID. CONTRACEPTION FERTILITE SEXUALITE, 10(9), 547-549. Retrieved from https://www.webofscience.com/

Journal article

ORAL-CONTRACEPTIVE STEROID PLASMA-CONCENTRATIONS IN SMOKERS AND NON SMOKERS

CRAWFORD, F. E., BACK, D. J., ORME, M. L. E., & BRECKENRIDGE, A. M. (1982). ORAL-CONTRACEPTIVE STEROID PLASMA-CONCENTRATIONS IN SMOKERS AND NON SMOKERS. CONTRACEPTION FERTILITE SEXUALITE, 10(3), 143-148. Retrieved from https://www.webofscience.com/

Journal article

THE EFFECTS OF AMPICILLIN ON ORAL-CONTRACEPTIVE STEROIDS IN WOMEN

BACK, D. J., BRECKENRIDGE, A. M., MACIVER, M., ORME, M., ROWE, P. H., STAIGER, C., . . . TJIA, J. (1982). THE EFFECTS OF AMPICILLIN ON ORAL-CONTRACEPTIVE STEROIDS IN WOMEN. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 14(1), 43-48. doi:10.1111/j.1365-2125.1982.tb04932.x

DOI
10.1111/j.1365-2125.1982.tb04932.x
Journal article

THE ENZYME INDUCING EFFECT OF RIFAMPICIN IN THE RHESUS-MONKEY AND ITS LACK OF INTERACTION WITH ORAL-CONTRACEPTIVE STEROIDS

BACK, D. J., BARKFELDT, J. O., BRECKENRIDGE, A. M., ODLIND, V., ORME, M., PARK, B. K., . . . VICTOR, A. (1982). THE ENZYME INDUCING EFFECT OF RIFAMPICIN IN THE RHESUS-MONKEY AND ITS LACK OF INTERACTION WITH ORAL-CONTRACEPTIVE STEROIDS. CONTRACEPTION, 25(3), 307-316. doi:10.1016/0010-7824(82)90054-3

DOI
10.1016/0010-7824(82)90054-3
Journal article

THE GUT WALL METABOLISM OF ETHINYLESTRADIOL AND ITS CONTRIBUTION TO THE PRE-SYSTEMIC METABOLISM OF ETHINYLESTRADIOL IN HUMANS

BACK, D. J., BRECKENRIDGE, A. M., MACIVER, M., ORME, M., PURBA, H. S., ROWE, P. H., & TAYLOR, I. (1982). THE GUT WALL METABOLISM OF ETHINYLESTRADIOL AND ITS CONTRIBUTION TO THE PRE-SYSTEMIC METABOLISM OF ETHINYLESTRADIOL IN HUMANS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 13(3), 325-330. doi:10.1111/j.1365-2125.1982.tb01382.x

DOI
10.1111/j.1365-2125.1982.tb01382.x
Journal article

1981

INTERACTION OF ETHINYLESTRADIOL WITH ASCORBIC-ACID - REPLY

BACK, D. J., BRECKENRIDGE, A. M., & ORME, M. L. E. (1981). INTERACTION OF ETHINYLESTRADIOL WITH ASCORBIC-ACID - REPLY. BRITISH MEDICAL JOURNAL, 282(6281), 2057. doi:10.1136/bmj.282.6281.2057-a

DOI
10.1136/bmj.282.6281.2057-a
Journal article

ORAL-CONTRACEPTIVE STEROID PLASMA-CONCENTRATIONS IN SMOKERS AND NON-SMOKERS

CRAWFORD, F. E., BACK, D. J., ORME, M. L. E., & BRECKENRIDGE, A. M. (1981). ORAL-CONTRACEPTIVE STEROID PLASMA-CONCENTRATIONS IN SMOKERS AND NON-SMOKERS. BRITISH MEDICAL JOURNAL, 282(6279), 1829-1830. doi:10.1136/bmj.282.6279.1829

DOI
10.1136/bmj.282.6279.1829
Journal article

INTERACTION OF ETHINYLESTRADIOL WITH ASCORBIC-ACID IN MAN

BACK, D. J., BRECKENRIDGE, A. M., MACIVER, M., ORME, M. L., PURBA, H., & ROWE, P. H. (1981). INTERACTION OF ETHINYLESTRADIOL WITH ASCORBIC-ACID IN MAN. BRITISH MEDICAL JOURNAL, 282(6275), 1516. doi:10.1136/bmj.282.6275.1516

DOI
10.1136/bmj.282.6275.1516
Journal article

ABSORPTION OF ESTRONE SULFATE FROM THE GASTROINTESTINAL-TRACT OF THE RAT

BACK, D. J., CHAPMAN, C. R., MAY, S. A., & ROWE, P. H. (1981). ABSORPTION OF ESTRONE SULFATE FROM THE GASTROINTESTINAL-TRACT OF THE RAT. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 14(4), 347-356. doi:10.1016/0022-4731(81)90153-9

DOI
10.1016/0022-4731(81)90153-9
Journal article

INTERINDIVIDUAL VARIATION AND DRUG-INTERACTIONS WITH HORMONAL STEROID-CONTRACEPTIVES

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., MACIVER, M., ORME, M. L. E., & ROWE, P. H. (1981). INTERINDIVIDUAL VARIATION AND DRUG-INTERACTIONS WITH HORMONAL STEROID-CONTRACEPTIVES. DRUGS, 21(1), 46-61. doi:10.2165/00003495-198121010-00003

DOI
10.2165/00003495-198121010-00003
Journal article

INTESTINAL-ABSORPTION OF ESTRONE SULFATE IN THE RAT

BACK, D. J., BRECKENRIDGE, A. M., CHAPMAN, C. R., CRAWFORD, F. E., ORME, M. L., & ROWE, P. H. (1981). INTESTINAL-ABSORPTION OF ESTRONE SULFATE IN THE RAT. BRITISH JOURNAL OF PHARMACOLOGY, 72(3), P541. Retrieved from https://www.webofscience.com/

Journal article

METABOLISM OF NORETHISTERONE OENANTHATE INVITRO

BACK, D. J., BRECKENRIDGE, A. M., CHAPMAN, C. R., CRAWFORD, F. E., ORME, M. L., & ROWE, P. H. (1981). METABOLISM OF NORETHISTERONE OENANTHATE INVITRO. BRITISH JOURNAL OF PHARMACOLOGY, 72(3), P538. Retrieved from https://www.webofscience.com/

Journal article

STUDIES ON THE ENZYMATIC CLEAVAGE OF NORETHISTERONE OENANTHATE

BACK, D. J., BRECKENRIDGE, A. M., CHAPMAN, C. R., CRAWFORD, F. E., OLSEN, K. A., ORME, M. L. E., & ROWE, P. H. (1981). STUDIES ON THE ENZYMATIC CLEAVAGE OF NORETHISTERONE OENANTHATE. CONTRACEPTION, 23(2), 125-132. doi:10.1016/0010-7824(81)90098-6

DOI
10.1016/0010-7824(81)90098-6
Journal article

THE EFFECT OF CIGARETTE-SMOKING ON PLASMA-CONCENTRATIONS OF ORAL-CONTRACEPTIVE STEROIDS

CRAWFORD, F. E., BACK, D. J., ORME, M. L., & BRECKENRIDGE, A. M. (1981). THE EFFECT OF CIGARETTE-SMOKING ON PLASMA-CONCENTRATIONS OF ORAL-CONTRACEPTIVE STEROIDS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 11(4), P438-P439. Retrieved from https://www.webofscience.com/

Journal article

THE INVITRO METABOLISM OF ETHINYLESTRADIOL, MESTRANOL AND LEVONORGESTREL BY HUMAN JEJUNAL MUCOSA

BACK, D. J., BATES, M., BRECKENRIDGE, A. M., ELLIS, A., HALL, J. M., MACIVER, M., . . . ROWE, P. H. (1981). THE INVITRO METABOLISM OF ETHINYLESTRADIOL, MESTRANOL AND LEVONORGESTREL BY HUMAN JEJUNAL MUCOSA. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 11(3), 275-278. doi:10.1111/j.1365-2125.1981.tb00534.x

DOI
10.1111/j.1365-2125.1981.tb00534.x
Journal article

THE PHARMACOKINETICS OF ESTRONE SULFATE IN THE RAT

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., GILES, M., ORME, M. L. E., & ROWE, P. H. (1981). THE PHARMACOKINETICS OF ESTRONE SULFATE IN THE RAT. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 14(10), 1045-1047. doi:10.1016/0022-4731(81)90214-4

DOI
10.1016/0022-4731(81)90214-4
Journal article

THE PHARMACOKINETICS OF LEVONORGESTREL AND ETHYNYLESTRADIOL IN WOMEN - STUDIES WITH OVRAN AND OVRANETTE

BACK, D. J., BATES, M., BRECKENRIDGE, A. M., HALL, J. M., MACIVER, M., ORME, M. L. E., . . . ROWE, P. H. (1981). THE PHARMACOKINETICS OF LEVONORGESTREL AND ETHYNYLESTRADIOL IN WOMEN - STUDIES WITH OVRAN AND OVRANETTE. CONTRACEPTION, 23(3), 229-239. doi:10.1016/0010-7824(81)90045-7

DOI
10.1016/0010-7824(81)90045-7
Journal article

1980

Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids.

Breckenridge, A. M., Back, D. J., Cross, K., Crawford, F., MacIver, M., Orme, M. L., . . . Smith, E. (1980). Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids.. Ciba Foundation symposium, 76, 289-306. doi:10.1002/9780470720592.ch16

DOI
10.1002/9780470720592.ch16
Journal article

INTERACTION OF ANTIBIOTICS WITH ETHINYLESTRADIOL IN THE RAT AND RABBIT

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., CROSS, K. J., ORME, M. L. E., & ROWE, P. H. (1980). INTERACTION OF ANTIBIOTICS WITH ETHINYLESTRADIOL IN THE RAT AND RABBIT. BRITISH JOURNAL OF PHARMACOLOGY, 68(1), P118. Retrieved from https://www.webofscience.com/

Journal article

Clinical pharmacology of oral contraceptive steroids: drug interactions

Back, D. J., Breckenridge, A. M., Orme, M., & Rowe, P. H. (1980). Clinical pharmacology of oral contraceptive steroids: drug interactions. Journal of Obstetrics and Gynaecology, 1(2), 126-138. doi:10.3109/01443618009067363

DOI
10.3109/01443618009067363
Journal article

EFFECT OF ORAL-CONTRACEPTIVE STEROIDS AND ENZYME INDUCING DRUGS ON SEX-HORMONE BINDING GLOBULIN CAPACITY IN WOMEN

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., MACIVER, M., ORME, M. L. E., PERUCCA, E., . . . SMITH, E. (1980). EFFECT OF ORAL-CONTRACEPTIVE STEROIDS AND ENZYME INDUCING DRUGS ON SEX-HORMONE BINDING GLOBULIN CAPACITY IN WOMEN. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 9(1), P115. doi:10.1111/j.1365-2125.1980.tb04817.x

DOI
10.1111/j.1365-2125.1980.tb04817.x
Journal article

EFFECT OF RIFAMPICIN ON THE PHARMACOKINETICS OF ETHYNYLESTRADIOL IN WOMEN

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., HALL, J. M., MACIVER, M., ORME, M. L. E., . . . WATTS, M. J. (1980). EFFECT OF RIFAMPICIN ON THE PHARMACOKINETICS OF ETHYNYLESTRADIOL IN WOMEN. CONTRACEPTION, 21(2), 135-143. doi:10.1016/0010-7824(80)90125-0

DOI
10.1016/0010-7824(80)90125-0
Journal article

INVITRO METABOLISM OF ETHINYLESTRADIOL, LEVONORGESTREL AND MESTRANOL BY HUMAN JEJUNAL MUCOSA

BACK, D. J., BATES, M., BRECKENRIDGE, A. M., CRAWFORD, F. E., ELLIS, A., HALL, J. M., . . . ROWE, P. H. (1980). INVITRO METABOLISM OF ETHINYLESTRADIOL, LEVONORGESTREL AND MESTRANOL BY HUMAN JEJUNAL MUCOSA. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 9 (pp. P281-P282). doi:10.1111/j.1365-2125.1980.tb04841.x

DOI
10.1111/j.1365-2125.1980.tb04841.x
Conference Paper

PHARMACOKINETICS OF A LARGE (3 MG) ORAL DOSE OF ETHYNYLESTRADIOL IN WOMEN

BACK, D. J., BOLT, H. M., BRECKENRIDGE, A. M., CRAWFORD, F. E., ORME, M. L. E., ROWE, P. H., & SCHINDLER, A. E. (1980). PHARMACOKINETICS OF A LARGE (3 MG) ORAL DOSE OF ETHYNYLESTRADIOL IN WOMEN. CONTRACEPTION, 21(2), 145-153. doi:10.1016/0010-7824(80)90126-2

DOI
10.1016/0010-7824(80)90126-2
Journal article

PHENOBARBITONE INTERACTION WITH ORAL-CONTRACEPTIVE STEROIDS IN THE RABBIT AND RAT

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., ORME, M. L., & ROWE, P. H. (1980). PHENOBARBITONE INTERACTION WITH ORAL-CONTRACEPTIVE STEROIDS IN THE RABBIT AND RAT. BRITISH JOURNAL OF PHARMACOLOGY, 69(3), 441-452. doi:10.1111/j.1476-5381.1980.tb07033.x

DOI
10.1111/j.1476-5381.1980.tb07033.x
Journal article

REDUCTION OF THE ENTEROHEPATIC CIRCULATION OF NORETHISTERONE BY ANTIBIOTICS IN THE RAT - CORRELATION WITH CHANGES IN THE GUT FLORA

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., CROSS, K. J., ORME, M. L. E., PERCIVAL, A., & ROWE, P. H. (1980). REDUCTION OF THE ENTEROHEPATIC CIRCULATION OF NORETHISTERONE BY ANTIBIOTICS IN THE RAT - CORRELATION WITH CHANGES IN THE GUT FLORA. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 13(1), 95-100. doi:10.1016/0022-4731(80)90118-1

DOI
10.1016/0022-4731(80)90118-1
Journal article

THE INTERACTION OF PHENOBARBITAL AND OTHER ANTICONVULSANTS WITH ORAL-CONTRACEPTIVE STEROID-THERAPY

BACK, D. J., BATES, M., BOWDEN, A., BRECKENRIDGE, A. M., HALL, M. J., JONES, H., . . . SMITH, E. (1980). THE INTERACTION OF PHENOBARBITAL AND OTHER ANTICONVULSANTS WITH ORAL-CONTRACEPTIVE STEROID-THERAPY. CONTRACEPTION, 22(5), 495-503. doi:10.1016/0010-7824(80)90102-X

DOI
10.1016/0010-7824(80)90102-X
Journal article

1979

PHARMACOKINETICS OF ETHINYLESTRADIOL IN WOMEN

BACK, D. J., BOLT, H. M., BRECKENRIDGE, A. M., CRAWFORD, F. E., MACIVER, M., ORME, M. L. E., . . . SMITH, E. (1979). PHARMACOKINETICS OF ETHINYLESTRADIOL IN WOMEN. BRITISH JOURNAL OF PHARMACOLOGY, 66(3), P441-P442. Retrieved from https://www.webofscience.com/

Journal article

EFFECT OF RIFAMPICIN ON NORETHISTERONE PHARMACOKINETICS

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F., MACIVER, M., ORME, M. L., PARK, B. K., . . . SMITH, E. (1979). EFFECT OF RIFAMPICIN ON NORETHISTERONE PHARMACOKINETICS. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 15(3), 193-197. doi:10.1007/BF00563105

DOI
10.1007/BF00563105
Journal article

EFFECT OF RIFAMPICIN ON LIVER BLOOD-FLOW, MICROSOMAL-ENZYME ACTIVITY AND BILE-FLOW IN THE RAT

BACK, D. J., CROSS, K. J., HILEY, C. R., & YATES, M. S. (1979). EFFECT OF RIFAMPICIN ON LIVER BLOOD-FLOW, MICROSOMAL-ENZYME ACTIVITY AND BILE-FLOW IN THE RAT. BIOCHEMICAL PHARMACOLOGY, 28(8), 1293-1296. doi:10.1016/0006-2952(79)90427-1

DOI
10.1016/0006-2952(79)90427-1
Journal article

THERAPY WITH ORAL-CONTRACEPTIVE STEROIDS AND ANTIBIOTICS

LEORME, M., & BACK, D. J. (1979). THERAPY WITH ORAL-CONTRACEPTIVE STEROIDS AND ANTIBIOTICS. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 5(2), 124-126. doi:10.1093/jac/5.2.124

DOI
10.1093/jac/5.2.124
Journal article

EFFECTS OF PHENOBARBITONE ON HEPATIC MICROSOMAL-ENZYME ACTIVITY AND LIVER BLOOD-FLOW IN SPONTANEOUSLY HYPERTENSIVE RATS

YATES, M. S., HILEY, C. R., & BACK, D. J. (1979). EFFECTS OF PHENOBARBITONE ON HEPATIC MICROSOMAL-ENZYME ACTIVITY AND LIVER BLOOD-FLOW IN SPONTANEOUSLY HYPERTENSIVE RATS. LIFE SCIENCES, 24(6), 535-540. doi:10.1016/0024-3205(79)90175-9

DOI
10.1016/0024-3205(79)90175-9
Journal article

INTERACTIONS BETWEEN ORAL-CONTRACEPTIVES AND OTHER DRUGS

BRECKENRIDGE, A. M., BACK, D. J., & ORME, M. (1979). INTERACTIONS BETWEEN ORAL-CONTRACEPTIVES AND OTHER DRUGS. PHARMACOLOGY & THERAPEUTICS, 7(3), 617-626. doi:10.1016/0163-7258(79)90044-5

DOI
10.1016/0163-7258(79)90044-5
Journal article

INVESTIGATION OF THE PHARMACOKINETICS OF ETHYNYLESTRADIOL IN WOMEN USING RADIOIMMUNOASSAY

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., MACIVER, M., ORME, M. L. E., ROWE, P. H., & WATTS, M. J. (1979). INVESTIGATION OF THE PHARMACOKINETICS OF ETHYNYLESTRADIOL IN WOMEN USING RADIOIMMUNOASSAY. CONTRACEPTION, 20(3), 263-273. doi:10.1016/0010-7824(79)90098-2

DOI
10.1016/0010-7824(79)90098-2
Journal article

PLASMA XA INHIBITORY ACTIVITIES AND PLASMA-CONCENTRATIONS OF NORGESTREL AND ETHINYLESTRADIOL IN WOMEN ON ORAL-CONTRACEPTIVE STEROIDS

BACK, D. J., BATES, M., BURKE, M. W., BRECKENRIDGE, A. M., CRAWFORD, F. E., MACIVER, M., . . . WEBSTER, S. (1979). PLASMA XA INHIBITORY ACTIVITIES AND PLASMA-CONCENTRATIONS OF NORGESTREL AND ETHINYLESTRADIOL IN WOMEN ON ORAL-CONTRACEPTIVE STEROIDS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 8(5), 505-506. doi:10.1111/j.1365-2125.1979.tb01034.x

DOI
10.1111/j.1365-2125.1979.tb01034.x
Journal article

1978

Drug interactions with oral contraceptives.

Back, D. J., & Breckenridge, A. M. (1978). Drug interactions with oral contraceptives.. IPPF medical bulletin, 12(4), 1-2.

Journal article

First-pass effect of norethindrone in rabbits and rats.

Back, D. J., Breckenridge, A. M., Crawford, F. E., Orme, M. L., Rowe, P. H., & Smith, E. (1978). First-pass effect of norethindrone in rabbits and rats.. The Journal of pharmacology and experimental therapeutics, 207(2), 555-565.

Journal article

REDUCTION OF ENTEROHEPATIC CIRCULATION OF NORETHISTERONE BY ANTIBIOTICS IN RAT

BACK, D. J., BRECKENRIDGE, A. M., CROSS, K. J., ORME, M. L., PERCIVAL, A., & ROWE, P. H. (1978). REDUCTION OF ENTEROHEPATIC CIRCULATION OF NORETHISTERONE BY ANTIBIOTICS IN RAT. BRITISH JOURNAL OF PHARMACOLOGY, 64(3), P401. Retrieved from https://www.webofscience.com/

Journal article

BILIARY-EXCRETION OF SYNTHETIC SEX STEROIDS IN HETEROZYGOUS AND HOMOZYGOUS GUNN RATS

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., CROSS, K. J., ORME, M. L., ROWE, P. H., . . . TODD, K. (1978). BILIARY-EXCRETION OF SYNTHETIC SEX STEROIDS IN HETEROZYGOUS AND HOMOZYGOUS GUNN RATS. LIFE SCIENCES, 23(10), 1053-1056. doi:10.1016/0024-3205(78)90666-5

DOI
10.1016/0024-3205(78)90666-5
Journal article

EFFECT OF URETHANE AND PENTOBARBITAL ANESTHESIA AND HEPATIC PORTAL-VEIN CATHETERIZATION ON LIVER BLOOD-FLOW IN RAT

HILEY, C. R., YATES, M. S., & BACK, D. J. (1978). EFFECT OF URETHANE AND PENTOBARBITAL ANESTHESIA AND HEPATIC PORTAL-VEIN CATHETERIZATION ON LIVER BLOOD-FLOW IN RAT. EXPERIENTIA, 34(8), 1061-1062. doi:10.1007/BF01915348

DOI
10.1007/BF01915348
Journal article

INTERACTION OF ANTIBIOTICS WITH SYNTHETIC STEROIDS IN RAT

BACK, D. J., BRECKENRIDGE, A. M., CHALLINER, M., CRAWFORD, F. E., ORME, M. L. E., ROWE, P. H., & SMITH, E. (1978). INTERACTION OF ANTIBIOTICS WITH SYNTHETIC STEROIDS IN RAT. BRITISH JOURNAL OF PHARMACOLOGY, 62(3), P441. Retrieved from https://www.webofscience.com/

Journal article

DIFFERENTIAL EFFECTS OF HEPATIC MICROSOMAL-ENZYME INDUCING AGENTS ON LIVER BLOOD-FLOW

YATES, M. S., HILEY, C. R., ROBERTS, P. J., BACK, D. J., & CRAWFORD, F. E. (1978). DIFFERENTIAL EFFECTS OF HEPATIC MICROSOMAL-ENZYME INDUCING AGENTS ON LIVER BLOOD-FLOW. BIOCHEMICAL PHARMACOLOGY, 27(22), 2617-2621. doi:10.1016/0006-2952(78)90336-2

DOI
10.1016/0006-2952(78)90336-2
Journal article

EFFECT OF ANTIBIOTICS ON ENTEROHEPATIC CIRCULATION OF ETHINYLESTRADIOL AND NORETHISTERONE IN RAT

BACK, D. J., BRECKENRIDGE, A. M., CHALLINER, M., CRAWFORD, F. E., ORME, M. L., ROWE, P. H., & SMITH, E. (1978). EFFECT OF ANTIBIOTICS ON ENTEROHEPATIC CIRCULATION OF ETHINYLESTRADIOL AND NORETHISTERONE IN RAT. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 9(6), 527-531. doi:10.1016/0022-4731(78)90118-8

DOI
10.1016/0022-4731(78)90118-8
Journal article

ETHYNYLESTRADIOL AND NORETHINDRONE METABOLISM BY EVERTED SACS OF RAT ILEUM

BACK, D. J., BATES, M. W., BRECKENRIDGE, A. M., CRAWFORD, F. E., ORME, M. L. E., ROWE, P. H., . . . SMITH, E. (1978). ETHYNYLESTRADIOL AND NORETHINDRONE METABOLISM BY EVERTED SACS OF RAT ILEUM. CONTRACEPTION, 18(2), 127-135. doi:10.1016/0010-7824(78)90088-4

DOI
10.1016/0010-7824(78)90088-4
Journal article

KINETICS OF NORETHINDRONE IN WOMEN .1. RADIOIMMUNOASSAY AND CONCENTRATIONS DURING MULTIPLE DOSING

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., MCIVER, M., ORME, M. L. E., PARK, B. K., . . . SMITH, E. (1978). KINETICS OF NORETHINDRONE IN WOMEN .1. RADIOIMMUNOASSAY AND CONCENTRATIONS DURING MULTIPLE DOSING. CLINICAL PHARMACOLOGY & THERAPEUTICS, 24(4), 439-447. Retrieved from https://www.webofscience.com/

Journal article

KINETICS OF NORETHINDRONE IN WOMEN .2. SINGLE-DOSE KINETICS

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., MCIVER, M., ORME, M. L. E., ROWE, P. H., & SMITH, E. (1978). KINETICS OF NORETHINDRONE IN WOMEN .2. SINGLE-DOSE KINETICS. CLINICAL PHARMACOLOGY & THERAPEUTICS, 24(4), 448-453. Retrieved from https://www.webofscience.com/

Journal article

METABOLISM OF NORETHISTERONE AND ETHINYLESTRADIOL BY RAT GUT WALL

BACK, D. J., BATES, M. W., BRECKENRIDGE, A. M., CRAWFORD, F. E., ORME, M. L. E., ROWE, P. H., . . . SMITH, E. (1978). METABOLISM OF NORETHISTERONE AND ETHINYLESTRADIOL BY RAT GUT WALL. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 9(9), 823. doi:10.1016/0022-4731(78)90751-3

DOI
10.1016/0022-4731(78)90751-3
Journal article

PHARMACOKINETICS OF TRITIATED ETHINYLESTRADIOL IN RABBIT

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., ORME, M. L. E., ROWE, P. H., SLOAN, T. P., & SMITH, E. (1978). PHARMACOKINETICS OF TRITIATED ETHINYLESTRADIOL IN RABBIT. STEROIDS, 32(4), 423-433. doi:10.1016/0039-128X(78)90056-9

DOI
10.1016/0039-128X(78)90056-9
Journal article

PLASMA ETHINYLESTRADIOL CONCENTRATION IN RABBITS AND WOMEN

BACK, D. J., BRECKENRIDGE, A. M., CRAWFORD, F. E., ORME, M. L. E., ROWE, P. H., SLOAN, T. P., & SMITH, E. (1978). PLASMA ETHINYLESTRADIOL CONCENTRATION IN RABBITS AND WOMEN. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 9(9), 863. doi:10.1016/0022-4731(78)90942-1

DOI
10.1016/0022-4731(78)90942-1
Journal article

1977

PHARMACOKINETICS OF NORETHISTERONE IN RABBIT AND RAT AFTER SYSTEMIC AND ORAL-ADMINISTRATION - EFFECT OF PHENOBARBITONE

BACK, D. J., BRECKENRIDGE, A. M., GAY, F. E., ORME, M. L., ROWE, P. H., & SMITH, E. (1977). PHARMACOKINETICS OF NORETHISTERONE IN RABBIT AND RAT AFTER SYSTEMIC AND ORAL-ADMINISTRATION - EFFECT OF PHENOBARBITONE. BRITISH JOURNAL OF PHARMACOLOGY, 60(2), 279. Retrieved from https://www.webofscience.com/

Journal article

LSD - DISTRIBUTION OF [LSD[H-3] IN REPRODUCTIVE-SYSTEM OF MALE RAT AND PLACENTAL-TRANSFER IN FEMALE RAT

BACK, D. J., & SINGH, J. K. G. (1977). LSD - DISTRIBUTION OF [LSD[H-3] IN REPRODUCTIVE-SYSTEM OF MALE RAT AND PLACENTAL-TRANSFER IN FEMALE RAT. EXPERIENTIA, 33(4), 501-502. doi:10.1007/BF01922236

DOI
10.1007/BF01922236
Journal article

SOME EFFECTS OF CYPROTERONE AND CYPROTERONE-ACETATE ON REPRODUCTIVE PHYSIOLOGY OF MALE RAT

BACK, D. J., GLOVER, T. D., SHENTON, J. C., & BOYD, G. P. (1977). SOME EFFECTS OF CYPROTERONE AND CYPROTERONE-ACETATE ON REPRODUCTIVE PHYSIOLOGY OF MALE RAT. JOURNAL OF REPRODUCTION AND FERTILITY, 49(2), 237-243. Retrieved from https://www.webofscience.com/

Journal article

Drug interactions with oral contraceptive steroids

Back, D. J., & L'E Orme, M. (1977). Drug interactions with oral contraceptive steroids. Prescribers' Journal, 17(6), 137-142.

Journal article

INFLUENCE OF .A. ROUTE OF ADMINISTRATION AND .B. PHENOBARBITONE ON PHARMACOKINETICS OF NORETHISTERONE IN RABBIT AND RAT

BACK, D. J., BRECKENRIDGE, A. M., GAY, F. E., ORME, M. L., PARK, B. K., ROWE, P. H., & SMITH, E. (1977). INFLUENCE OF .A. ROUTE OF ADMINISTRATION AND .B. PHENOBARBITONE ON PHARMACOKINETICS OF NORETHISTERONE IN RABBIT AND RAT. ACTA ENDOCRINOLOGICA, 85, 67. Retrieved from https://www.webofscience.com/

Journal article

PHARMACOKINETICS OF NORETHISTERONE DURING SINGLE AND MULTIPLE DOSING IN WOMEN AND CHANGES CAUSED BY RIFAMPICIN

BACK, D. J., BRECKENRIDGE, A. M., GAY, F. E., ORME, M. L. E., PARK, B. K., ROWE, P. H., & SMITH, E. (1977). PHARMACOKINETICS OF NORETHISTERONE DURING SINGLE AND MULTIPLE DOSING IN WOMEN AND CHANGES CAUSED BY RIFAMPICIN. ACTA ENDOCRINOLOGICA, 85, 149. Retrieved from https://www.webofscience.com/

Journal article

PHARMACOKINETICS OF NORETHISTERONE IN WOMEN

BACK, D. J., BRECKENRIDGE, A. M., GAY, F. E., MCIVER, M., ORME, M. L., PARK, B. K., . . . SMITH, E. (1977). PHARMACOKINETICS OF NORETHISTERONE IN WOMEN. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 4(6), P729-P730. Retrieved from https://www.webofscience.com/

Journal article

1976

BILIARY-EXCRETION OF [H-3] LYSERGIC-ACID DIETHYLAMIDE IN WISTAR AND GUNN RATS

BACK, D. J., & SINGH, J. K. G. (1976). BILIARY-EXCRETION OF [H-3] LYSERGIC-ACID DIETHYLAMIDE IN WISTAR AND GUNN RATS. EXPERIENTIA, 32(5), 616-617. doi:10.1007/BF01990195

DOI
10.1007/BF01990195
Journal article

RELEASE OF MICROQUANTITIES OF CYPROTERONE-ACETATE FROM SUBCUTANEOUS SILASTIC CAPSULES - FAILURE TO PRODUCE AN ANTIFERTILITY EFFECT

BACK, D. J., & SHENTON, J. C. (1976). RELEASE OF MICROQUANTITIES OF CYPROTERONE-ACETATE FROM SUBCUTANEOUS SILASTIC CAPSULES - FAILURE TO PRODUCE AN ANTIFERTILITY EFFECT. CONTRACEPTION, 14(1), 17-24. doi:10.1016/S0010-7824(76)80004-2

DOI
10.1016/S0010-7824(76)80004-2
Journal article

1975

EFFECTS OF ALPHA-CHLOROHYDRIN ON COMPOSITION OF RAT AND RABBIT EPIDIDYMAL PLASMA - POSSIBLE EXPLANATION OF SPECIES-DIFFERENCE

BACK, D. J., GLOVER, T. D., SHENTON, J. C., & BOYD, G. P. (1975). EFFECTS OF ALPHA-CHLOROHYDRIN ON COMPOSITION OF RAT AND RABBIT EPIDIDYMAL PLASMA - POSSIBLE EXPLANATION OF SPECIES-DIFFERENCE. JOURNAL OF REPRODUCTION AND FERTILITY, 45(1), 117-128. Retrieved from https://www.webofscience.com/

Journal article

COMPARISON OF COMPOSITION OF EPIDIDYMAL PLASMA FROM CAUDA EPIDIDYMIDIS OF RAT, HAMSTER AND GUINEA-PIG

BACK, D. J., & SHENTON, J. C. (1975). COMPARISON OF COMPOSITION OF EPIDIDYMAL PLASMA FROM CAUDA EPIDIDYMIDIS OF RAT, HAMSTER AND GUINEA-PIG. EXPERIENTIA, 31(4), 464-465. doi:10.1007/BF02026381

DOI
10.1007/BF02026381
Journal article

PRESENCE OF METABOLITES OF H-3-TESTOSTERONE IN LUMEN OF CAUDA EPIDIDYMIDIS OF RAT

BACK, D. J. (1975). PRESENCE OF METABOLITES OF H-3-TESTOSTERONE IN LUMEN OF CAUDA EPIDIDYMIDIS OF RAT. STEROIDS, 25(3), 413-420. doi:10.1016/0039-128X(75)90097-5

DOI
10.1016/0039-128X(75)90097-5
Journal article

1974

The composition of epididymal plasma from the cauda epididymidis of the rat.

Back, D. J., Shenton, J. C., & Glover, T. D. (1974). The composition of epididymal plasma from the cauda epididymidis of the rat.. Journal of reproduction and fertility, 40(1), 211-214. doi:10.1530/jrf.0.0400211

DOI
10.1530/jrf.0.0400211
Journal article

The pharmacokinetics of (14C)-edrophonium in normal wistar rats and homozygous Gunn rats with ligated renal pedicles.

Back, D. J., & Calvey, T. N. (1974). The pharmacokinetics of (14C)-edrophonium in normal wistar rats and homozygous Gunn rats with ligated renal pedicles.. British journal of pharmacology, 51(1), 61-65. doi:10.1111/j.1476-5381.1974.tb09632.x

DOI
10.1111/j.1476-5381.1974.tb09632.x
Journal article

1973

Proceedings: The passage of (3H) testosterone into the cauda epididymidis of the rat.

Back, D. J. (1973). Proceedings: The passage of (3H) testosterone into the cauda epididymidis of the rat.. Journal of reproduction and fertility, 35(3), 586-587. doi:10.1530/jrf.0.0350586

DOI
10.1530/jrf.0.0350586
Journal article

Biliary excretion of 14 C-edrophonium and its glucuronide metabolite in Gunn rats.

Calvey, T. N., & Back, D. J. (1973). Biliary excretion of 14 C-edrophonium and its glucuronide metabolite in Gunn rats.. Archives internationales de pharmacodynamie et de therapie, 201(1), 147-153.

Journal article

1972

The influence of secretin on the elimination of 14 C-endrophonium in bile.

Back, D. J., & Calvey, T. N. (1972). The influence of secretin on the elimination of 14 C-endrophonium in bile.. Experientia, 28(11), 1332-1334. doi:10.1007/bf01965328

DOI
10.1007/bf01965328
Journal article

Excretion of 14 C-edrophonium and its metabolites in bile: role of the liver cell and the peribiliary vascular plexus.

Back, D. J., & Calvey, T. N. (1972). Excretion of 14 C-edrophonium and its metabolites in bile: role of the liver cell and the peribiliary vascular plexus.. British journal of pharmacology, 44(3), 534-543. doi:10.1111/j.1476-5381.1972.tb07290.x

DOI
10.1111/j.1476-5381.1972.tb07290.x
Journal article

The removal of 14 C-edrophonium from the circulation.

Back, D. J., & Calvey, T. N. (1972). The removal of 14 C-edrophonium from the circulation.. British journal of pharmacology, 46(2), 355-357. doi:10.1111/j.1476-5381.1972.tb06882.x

DOI
10.1111/j.1476-5381.1972.tb06882.x
Journal article

1971

Infusion of secretin into the hepatic arterial circulation of the rat.

Back, D. J., & Calvey, T. N. (1971). Infusion of secretin into the hepatic arterial circulation of the rat.. The Journal of physiology, 219(2), 14P.

Journal article

The influence of secretion on the elimination of drugs in bile.

Back, D. J., & Calvey, T. N. (1971). The influence of secretion on the elimination of drugs in bile.. The Journal of physiology, 219(2), 13P.

Journal article

Biliary excretion of (14C) edrophonium and its glucuronide conjugate.

Calvey, T. N., & Back, D. J. (1971). Biliary excretion of (14C) edrophonium and its glucuronide conjugate.. The Journal of pharmacy and pharmacology, 23(8), 642-643. doi:10.1111/j.2042-7158.1971.tb08738.x

DOI
10.1111/j.2042-7158.1971.tb08738.x
Journal article

The effect of organic anions on the biliary excretion of tri (14C) methyl-(3-hydroxyphenyl) ammonium O-glucuronide.

Calvey, T. N., & Back, D. J. (1971). The effect of organic anions on the biliary excretion of tri (14C) methyl-(3-hydroxyphenyl) ammonium O-glucuronide.. The Biochemical journal, 121(3), 41P-42P. doi:10.1042/bj1210041pb

DOI
10.1042/bj1210041pb
Journal article

The effect of bile pigments on the excretion of 14C-trimophonium glucuronide.

Calvey, T. N., & Back, D. J. (1971). The effect of bile pigments on the excretion of 14C-trimophonium glucuronide.. European journal of pharmacology, 13(2), 262-265. doi:10.1016/0014-2999(71)90159-2

DOI
10.1016/0014-2999(71)90159-2
Journal article