Skip to main content

Publications

What type of publication do you want to show?

2024

2023

Airway metabolic profiling during <i>Streptococcus pneumoniae</i> infection identifies branched chain amino acids as signatures of upper airway colonisation

Green, A. E., Pottenger, S., Monshi, M. S., Barton, T. E., Phelan, M., & Neill, D. R. (2023). Airway metabolic profiling during <i>Streptococcus pneumoniae</i> infection identifies branched chain amino acids as signatures of upper airway colonisation. PLOS PATHOGENS, 19(9). doi:10.1371/journal.ppat.1011630

DOI
10.1371/journal.ppat.1011630
Journal article

Identification of two distinct phylogenomic lineages and model strains for the understudied cystic fibrosis lung pathogen <i>Burkholderia multivorans</i>.

Parfitt, K. M., Green, A. E., Connor, T. R., Neill, D. R., & Mahenthiralingam, E. (2023). Identification of two distinct phylogenomic lineages and model strains for the understudied cystic fibrosis lung pathogen <i>Burkholderia multivorans</i>.. Microbiology (Reading, England), 169(8). doi:10.1099/mic.0.001366

DOI
10.1099/mic.0.001366
Journal article

Identification of two distinct phylogenomic lineages and model strains for the understudied cystic fibrosis lung pathogen<i>Burkholderia multivorans</i>

DOI
10.1101/2023.01.03.522605
Preprint

2022

2021

<i>Pseudomonas aeruginosa</i> utilises host-derived polyamines to facilitate antimicrobial tolerance

DOI
10.1101/2021.12.15.472801
Preprint

2020

Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease

Shears, R. K., Jacques, L. C., Naylor, G., Miyashita, L., Shadia, K., Lebre, F., . . . Kadioglu, A. (2020). Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease. Journal of Allergy and Clinical Immunology, 145(4), 1272-1284.e6. doi:10.1016/j.jaci.2019.11.039

DOI
10.1016/j.jaci.2019.11.039
Journal article

2019

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival

Subramanian, K., Neill, D. R., Malak, H., Spelmink, L., Khandaker, S., Marchiori, G., . . . Henriques-Normark, B. (2019). Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival. Nature Microbiology, 4(1), 62-70. doi:10.1038/s41564-018-0280-x

DOI
10.1038/s41564-018-0280-x
Journal article

Pneumolysin interaction with the mannose receptor promotes pneumococcal invasion of the airways by blocking inflammatory responses

Subramanian, K., Neill, D. R., Malak, H. A., Spelmink, L., Khandaker, S., Marchiori, G. D. L., . . . Henriques-Normark, B. (2019). Pneumolysin interaction with the mannose receptor promotes pneumococcal invasion of the airways by blocking inflammatory responses. In SCANDINAVIAN JOURNAL OF IMMUNOLOGY Vol. 90. Retrieved from https://www.webofscience.com/

Conference Paper

2018

2017

2016

Pneumococcal Biology, Diversity, Evolution and Host Responses to Infection

Neill, D. R., Yang, M., & Kadioglu, A. (2016). Pneumococcal Biology, Diversity, Evolution and Host Responses to Infection. In ENCYCLOPEDIA OF IMMUNOBIOLOGY, VOL 4: IMMUNITY TO PATHOGENS AND TUMORS (pp. 60-65). doi:10.1016/B978-0-12-374279-7.13019-X

DOI
10.1016/B978-0-12-374279-7.13019-X
Chapter

2015

Ca²⁺-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins.

Wolfmeier, H., Schoenauer, R., Atanassoff, A. P., Neill, D. R., Kadioglu, A., Draeger, A., & Babiychuk, E. B. (2015). Ca²⁺-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins.. Biochimica et biophysica acta, 1853(9), 2045-2054. doi:10.1016/j.bbamcr.2014.09.005

DOI
10.1016/j.bbamcr.2014.09.005
Journal article

Pneumolysin

Neill, D. R., Mitchell, T. J., & Kadioglu, A. (2015). Pneumolysin. In Streptococcus Pneumoniae (pp. 257-275). Elsevier. doi:10.1016/b978-0-12-410530-0.00014-4

DOI
10.1016/b978-0-12-410530-0.00014-4
Chapter

2014

Pseudomonas aeruginosa adaptation in the nasopharyngeal reservoir leads to migration and persistence in the lungs.

Fothergill, J. L., Neill, D. R., Loman, N., Winstanley, C., & Kadioglu, A. (2014). Pseudomonas aeruginosa adaptation in the nasopharyngeal reservoir leads to migration and persistence in the lungs.. Nature Communications, 5, 9 pages. doi:10.1038/ncomms5780

DOI
10.1038/ncomms5780
Journal article

Ca<SUP>2+</SUP>-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins

Wolfmeier, H., Schoenauer, R., Atanassoff, A. P., Neill, D. R., Kadioglu, A., Draeger, A., & Babiychuk, E. B. (2015). Ca<SUP>2+</SUP>-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1853(9), 2045-2054. doi:10.1016/j.bbamcr.2014.09.005

DOI
10.1016/j.bbamcr.2014.09.005
Journal article

THE B LYMPHOCYTE DIFFERENTIATION FACTOR (BAFF) IS EXPRESSED IN THE AIRWAYS OF CHILDREN WITH CF AND IN LUNGS OF MICE INFECTED WITH PSEUDOMONAS AERUGINOSA

Neill, D. R., Saint, G. L., Bricio-Moreno, L., Fothergill, J., Southern, K. W., Winstanley, C., . . . Flanagan, B. F. (2014). THE B LYMPHOCYTE DIFFERENTIATION FACTOR (BAFF) IS EXPRESSED IN THE AIRWAYS OF CHILDREN WITH CF AND IN LUNGS OF MICE INFECTED WITH PSEUDOMONAS AERUGINOSA. PLoS One, 9(5). doi:10.1371/journal.pone.0095892.

DOI
10.1371/journal.pone.0095892.
Journal article

Density and duration of pneumococcal carriage is maintained by transforming growth factor β1 and T regulatory cells.

Neill, D., Coward, W. R., Gritzfeld, J., Richards, L., Garcia-Garcia, F. J., Dotor, J., . . . Kadioglu, A. (2014). Density and duration of pneumococcal carriage is maintained by transforming growth factor β1 and T regulatory cells.. American journal of respiratory and critical care medicine, 189(10), 1250-1259. doi:10.1164/rccm.201401-0128OC

DOI
10.1164/rccm.201401-0128OC
Journal article

The Pneumococcal Polysaccharide Capsule and Pneumolysin Differentially Affect CXCL8 and IL-6 Release from Cells of the Upper and Lower Respiratory Tract

Kueng, E., Coward, W. R., Neill, D. R., Malak, H. A., Muehlemann, K., Kadioglu, A., . . . Hathaway, L. J. (2014). The Pneumococcal Polysaccharide Capsule and Pneumolysin Differentially Affect CXCL8 and IL-6 Release from Cells of the Upper and Lower Respiratory Tract. PLOS ONE, 9(3). doi:10.1371/journal.pone.0092355

DOI
10.1371/journal.pone.0092355
Journal article

A new protective role for S100A9 in regulation of neutrophil recruitment during invasive pneumococcal pneumonia

De Filippo, K., Neill, D. R., Mathies, M., Bangert, M., McNeill, E., Kadioglu, A., & Hogg, N. (2014). A new protective role for S100A9 in regulation of neutrophil recruitment during invasive pneumococcal pneumonia. FASEB JOURNAL, 28(8), 3600-3608. doi:10.1096/fj.13-247460

DOI
10.1096/fj.13-247460
Journal article

2013

IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction

Barlow, J. L., Peel, S., Fox, J., Panova, V., Hardman, C. S., Camelo, A., . . . McKenzie, A. N. J. (2013). IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 132(4), 933-941. doi:10.1016/j.jaci.2013.05.012

DOI
10.1016/j.jaci.2013.05.012
Journal article

Nasopharyngeal carriage with Streptococcus pneumoniae augments the immunizing effect of pneumolysin toxoid B

Neill, D. R., Smeaton, S., Bangert, M., & Kadioglu, A. (2013). Nasopharyngeal carriage with Streptococcus pneumoniae augments the immunizing effect of pneumolysin toxoid B. Journal of Allergy and Clinical Immunology, 131(5), 1433-1435.e1. doi:10.1016/j.jaci.2012.11.004

DOI
10.1016/j.jaci.2012.11.004
Journal article

Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults

Ferreira, D. M., Neill, D. R., Bangert, M., Gritzfeld, J. F., Green, N., Wright, A. K. A., . . . Gordon, S. B. (2013). Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187(8), 855-864. doi:10.1164/rccm.201212-2277OC

DOI
10.1164/rccm.201212-2277OC
Journal article

<i>Spir2</i>; a novel QTL on chromosome 4 contributes to susceptibility to pneumococcal infection in mice

Wisby, L., Fernandes, V. E., Neill, D. R., Kadioglu, A., Andrew, P. W., & Denny, P. (2013). <i>Spir2</i>; a novel QTL on chromosome 4 contributes to susceptibility to pneumococcal infection in mice. BMC GENOMICS, 14. doi:10.1186/1471-2164-14-242

DOI
10.1186/1471-2164-14-242
Journal article

Nasopharyngeal carriage with <i>Streptococcus pneumoniae</i> augments the immunizing effect of pneumolysin toxoid B

Neill, D. R., Smeaton, S., Bangert, M., & Kadioglu, A. (2013). Nasopharyngeal carriage with <i>Streptococcus pneumoniae</i> augments the immunizing effect of pneumolysin toxoid B. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 131(5), 1433-+. doi:10.1016/j.jaci.2012.11.004

DOI
10.1016/j.jaci.2012.11.004
Journal article

Nasopharyngeal carriage with Streptococcus pneumoniae augments the immunizing effect of pneumolysin toxoid B

Neill, D. R., Smeaton, S., Bangert, M., & Kadioglu, A. (2013). Nasopharyngeal carriage with Streptococcus pneumoniae augments the immunizing effect of pneumolysin toxoid B. Journal of Allergy and Clinical Immunology, 131(5), 1433-1435. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/23260752

Journal article

TGFb and T regulatory cells mediate nasopharyngeal carriage of Streptococcus pneumoniae

Neill, D. R., Coward, W. R., Gritzfeld, J. F., Richards, L., Gordon, S. B., & Kadioglu, A. (2013). TGFb and T regulatory cells mediate nasopharyngeal carriage of Streptococcus pneumoniae. In IMMUNOLOGY Vol. 140 (pp. 101). Retrieved from https://www.webofscience.com/

Conference Paper

2012

Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.

Bricio-Moreno, L., Chaguza, C., Yahya, R., Shears, R. K., Cornick, J. E., Hokamp, K., . . . Kadioglu, A. (2012). Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.. mBio, 11(6). doi:10.1093/infdis/jis223

DOI
10.1093/infdis/jis223
Journal article

T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice

Neill, D. R., Fernandes, V. E., Wisby, L., Haynes, A. R., Ferreira, D. M., Laher, A., . . . Andrew, P. W. (2012). T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice. PLOS PATHOGENS, 8(4). doi:10.1371/journal.ppat.1002660

DOI
10.1371/journal.ppat.1002660
Journal article

Transcription factor RORα is critical for nuocyte development

Wong, S. H., Walker, J. A., Jolin, H. E., Drynan, L. F., Hams, E., Camelo, A., . . . McKenzie, A. N. J. (2012). Transcription factor RORα is critical for nuocyte development. NATURE IMMUNOLOGY, 13(3), 229-U43. doi:10.1038/ni.2208

DOI
10.1038/ni.2208
Journal article

Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13

Camelo, A., Barlow, J. L., Drynan, L. F., Neill, D. R., Ballantyne, S. J., Wong, S. H., . . . McKenzie, A. N. J. (2012). Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13. JOURNAL OF GASTROENTEROLOGY, 47(11), 1198-1211. doi:10.1007/s00535-012-0591-2

DOI
10.1007/s00535-012-0591-2
Journal article

2011

Novel Immunogenic Peptides Elicit Systemic Anaphylaxis in Mice: Implications for Peptide Vaccines

Smith, C. M., Bradding, P., Neill, D. R., Baxendale, H., Felici, F., & Andrew, P. W. (2011). Novel Immunogenic Peptides Elicit Systemic Anaphylaxis in Mice: Implications for Peptide Vaccines. JOURNAL OF IMMUNOLOGY, 187(3), 1201-1206. doi:10.4049/jimmunol.1002152

DOI
10.4049/jimmunol.1002152
Journal article

Nuocytes and beyond: new insights into helminth expulsion

Neill, D. R., & McKenzie, A. N. J. (2011). Nuocytes and beyond: new insights into helminth expulsion. TRENDS IN PARASITOLOGY, 27(5), 214-221. doi:10.1016/j.pt.2011.01.001

DOI
10.1016/j.pt.2011.01.001
Journal article

2010

T<sub>H</sub>9: the latest addition to the expanding repertoire of IL-25 targets

Neill, D. R., & McKenzie, A. N. J. (2010). T<sub>H</sub>9: the latest addition to the expanding repertoire of IL-25 targets. IMMUNOLOGY AND CELL BIOLOGY, 88(5), 502-504. doi:10.1038/icb.2010.43

DOI
10.1038/icb.2010.43
Journal article

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Neill, D. R., Wong, S. H., Bellosi, A., Flynn, R. J., Daly, M., Langford, T. K. A., . . . McKenzie, A. N. J. (2010). Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. NATURE, 464(7293), 1367-13U9. doi:10.1038/nature08900

DOI
10.1038/nature08900
Journal article