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Professor Dan Hawcutt
BSc (Hons), MB ChB (Hons), MD, MRCPCH

Reader in Paediatric Clinical Pharmacology
Women's & Children's Health
Part of
Institute of Life Course & Medical Sciences
Faculty of Health and Life Sciences

Contact

D.Hawcutt@liverpool.ac.uk

+44 (0)151 228 4811 Ext. 2441

Publications

Selected publications

  1. Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study (Journal article - 2018)
  2. Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia. (Journal article - 2023)
  3. Factors Associated With Diabetic Ketoacidosis at Onset of Type 1 Diabetes Among Pediatric Patients: A Systematic Review. (Journal article - 2022)
  4. Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital (Journal article - 2022)
  5. Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium (Journal article - 2017)
  6. 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. (Journal article - 2018)
  7. <i>TPMT</i>, <i>COMT</i> and <i>ACYP2</i> genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity (Journal article - 2017)
  8. Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment (Journal article - 2016)
  9. Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression (Journal article - 2023)
  10. The readability of parent information leaflets in paediatric studies (Journal article - 2023)
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2024

Urine metabolomics signature reveals novel determinants of adrenal suppression in children taking inhaled corticosteroids to control asthma symptoms.

Tran, D. T., Chen, Y., Zheng, Y., Hecker, J., Hawcutt, D. B., Pirmohamed, M., . . . Dahlin, A. (2024). Urine metabolomics signature reveals novel determinants of adrenal suppression in children taking inhaled corticosteroids to control asthma symptoms.. Immunity, inflammation and disease, 12(7), e1315. doi:10.1002/iid3.1315

DOI
10.1002/iid3.1315
Journal article

Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.

Michael, B. D., Dunai, C., Needham, E. J., Tharmaratnam, K., Williams, R., Huang, Y., . . . Menon, D. K. (2024). Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.. Nature communications, 15(1), 2918. doi:10.1038/s41467-024-47320-6

DOI
10.1038/s41467-024-47320-6
Journal article

Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.

RECOVERY Collaborative Group. (2024). Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.. The Lancet. Child & adolescent health, S2352-4642(23)00316-4. doi:10.1016/s2352-4642(23)00316-4

DOI
10.1016/s2352-4642(23)00316-4
Journal article

2023

Diurnal salivary cortisol and cortisone concentrations in girls with Turner syndrome and healthy controls: a preliminary report.

Jones, L., Park, J., Dliso, S., Hawcutt, D., Shantsila, A., Lip, G. Y. H., & Blair, J. C. (2023). Diurnal salivary cortisol and cortisone concentrations in girls with Turner syndrome and healthy controls: a preliminary report.. Archives of disease in childhood, archdischild-2023-326270. doi:10.1136/archdischild-2023-326270

DOI
10.1136/archdischild-2023-326270
Journal article

Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.

LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators., Adhikari, N. K. J., Hashmi, M., Tirupakuzhi Vijayaraghavan, B. K., Haniffa, R., Beane, A., . . . Lamontagne, F. (2023). Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.. JAMA, 330(18), 1745-1759. doi:10.1001/jama.2023.21407

DOI
10.1001/jama.2023.21407
Journal article

Participant perceptions and experiences of a novel community-based respiratory longitudinal sampling method in Liverpool, UK: A mixed methods feasibility study.

German, E. L., Nabwera, H. M., Robinson, R., Shiham, F., Liatsikos, K., Parry, C. M., . . . Nikolaou, E. (2023). Participant perceptions and experiences of a novel community-based respiratory longitudinal sampling method in Liverpool, UK: A mixed methods feasibility study.. PloS one, 18(11), e0294133. doi:10.1371/journal.pone.0294133

DOI
10.1371/journal.pone.0294133
Journal article

Real time mapping of particulate matter (PM) concentrations and paediatric asthma emergency department (ED) visits

Holden, K., Lee, A., King, C., Olajide, O., Hawcutt, D., Higham, J., & Sinha, I. (2023). Real time mapping of particulate matter (PM) concentrations and paediatric asthma emergency department (ED) visits. In Paediatric asthma and allergy (pp. PA1621). European Respiratory Society. doi:10.1183/13993003.congress-2023.pa1621

DOI
10.1183/13993003.congress-2023.pa1621
Conference Paper

Use of air purifiers in homes to improve asthma outcomes for children: a pilot study protocol

Holden, K., Lee, A., Hawcutt, D., & Sinha, I. (2023). Use of air purifiers in homes to improve asthma outcomes for children: a pilot study protocol. In Paediatric asthma and allergy (pp. PA5370). European Respiratory Society. doi:10.1183/13993003.congress-2023.pa5370

DOI
10.1183/13993003.congress-2023.pa5370
Conference Paper

27 Risk factors of augmented renal clearance in critically ill children using iohexol clearance for renal function assessment

Thatparan, T., Marro, J., & Hawcutt, D. (2023). What domains related to medicines were measured in studies of burden of care for paediatric patients? A systematic review. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A10). doi:10.1136/archdischild-2023-ESDPPP.27

DOI
10.1136/archdischild-2023-ESDPPP.27
Conference Paper

POINT PREVALENCE STUDY OF PAEDIATRIC POLYPHARMACY

Moss, J., Rashed, A., Jensen, J., Wilson, J., Walker, L., & Hawcutt, D. (2023). POINT PREVALENCE STUDY OF PAEDIATRIC POLYPHARMACY. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A8). doi:10.1136/archdischild-2023-ESDPPP.25

DOI
10.1136/archdischild-2023-ESDPPP.25
Conference Paper

Participant perceptions and experiences of a novel community-based pilot respiratory longitudinal sampling method in Liverpool, UK

DOI
10.1101/2023.05.18.23289716
Preprint

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

Horby, P. W., Emberson, J. R., Basnyat, B., Campbell, M., Peto, L., Pessoa-Amorim, G., . . . Landray, M. J. (2023). Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 401(10387), 1499-1507. doi:10.1016/S0140-6736(23)00510-X

DOI
10.1016/S0140-6736(23)00510-X
Journal article

Nirsevimab for Prevention of RSV in Term and Late-Preterm Infants.

Muller, W. J., Madhi, S. A., Seoane Nuñez, B., Baca Cots, M., Bosheva, M., Dagan, R., . . . MELODY Study Group. (2023). Nirsevimab for Prevention of RSV in Term and Late-Preterm Infants.. The New England journal of medicine, 388(16), 1533-1534. doi:10.1056/nejmc2214773

DOI
10.1056/nejmc2214773
Journal article

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19 A Randomized Clinical Trial

Lawler, P. R., Derde, L. P. G., van de Veerdonk, F. L., McVerry, B. J., Huang, D. T., Berry, L. R., . . . Webb, S. A. (2023). Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19 A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 329(14), 1183-1196. doi:10.1001/jama.2023.4480

DOI
10.1001/jama.2023.4480
Journal article

Implementation of a centralized pharmacovigilance system in academic pan-European clinical trials: Experience from EU-Response and conect4children consortia.

Terzić, V., Levoyer, L., Figarella, M., Bigagli, E., Mercier, N., De Gastines, L., . . . c4c safety group. (2023). Implementation of a centralized pharmacovigilance system in academic pan-European clinical trials: Experience from EU-Response and conect4children consortia.. British journal of clinical pharmacology, 89(4), 1318-1328. doi:10.1111/bcp.15669

DOI
10.1111/bcp.15669
Journal article

For children admitted to hospital, what interventions improve medication safety on ward rounds? A systematic review.

King, C., Dudley, J., Mee, A., Tomlin, S., Tse, Y., Trivedi, A., . . . Royal College of Paediatrics and Child Health/Neonatal and Paediatric Pharmacist Group Joint Standing Committee on Medicines. (2023). For children admitted to hospital, what interventions improve medication safety on ward rounds? A systematic review.. Archives of disease in childhood, archdischild-2022-324772. doi:10.1136/archdischild-2022-324772

DOI
10.1136/archdischild-2022-324772
Journal article

Hypertension in Turner syndrome: a review of proposed mechanisms, management and new directions.

Jones, L., Blair, J., Hawcutt, D. B., Lip, G. Y. H., & Shantsila, A. (2023). Hypertension in Turner syndrome: a review of proposed mechanisms, management and new directions.. Journal of hypertension, 41(2), 203-211. doi:10.1097/hjh.0000000000003321

DOI
10.1097/hjh.0000000000003321
Journal article

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.

Hurkmans, E. G. E., Klumpers, M. J., Dello Russo, C., De Witte, W., Guchelaar, H. -J., Gelderblom, H., . . . Te Loo, D. M. W. M. (2023). Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.. Frontiers in pharmacology, 13, 980309. doi:10.3389/fphar.2022.980309

DOI
10.3389/fphar.2022.980309
Journal article

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.

Writing Committee for the REMAP-CAP Investigators., Higgins, A. M., Berry, L. R., Lorenzi, E., Murthy, S., McQuilten, Z., . . . Lawler, P. R. (2023). Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.. JAMA, 329(1), 39-51. doi:10.1001/jama.2022.23257

DOI
10.1001/jama.2022.23257
Journal article

2022

PMON268 A Multicenter, Open Label, Variable Dose, Two-Arm, Pilot Paediatric Phase 1 Pk Study To Evaluate 4.5% Testosterone Nasal Gel In Hypogonadal Boys

Lucas-Herald, A., Hawcutt, D., Thankamony, A., & Faisal Ahmed, S. (2022). PMON268 A Multicenter, Open Label, Variable Dose, Two-Arm, Pilot Paediatric Phase 1 Pk Study To Evaluate 4.5% Testosterone Nasal Gel In Hypogonadal Boys. Journal of the Endocrine Society, 6(Supplement_1), A705. doi:10.1210/jendso/bvac150.1453

DOI
10.1210/jendso/bvac150.1453
Journal article

Mean glucose concentrations are increased, and cardiovascular risk factors are common in children and young people with secondary adrenal insufficiency (GRACE2)

Park, J., Jones, L., Dliso, S., Hawcutt, D., Shantsila, A., Lip, G., & Blair, J. (n.d.). Mean glucose concentrations are increased, and cardiovascular risk factors are common in children and young people with secondary adrenal insufficiency (GRACE2). Endocrine Abstracts. doi:10.1530/endoabs.85.p3

DOI
10.1530/endoabs.85.p3
Journal article

Salivary adrenal biomarkers differ depending on age and sex in healthy children: preliminary data

Park, J., Jones, L., Dliso, S., Bright, O., Walker, L., Grasim, I., . . . Blair, J. (n.d.). Salivary adrenal biomarkers differ depending on age and sex in healthy children: preliminary data. Endocrine Abstracts. doi:10.1530/endoabs.85.p2

DOI
10.1530/endoabs.85.p2
Journal article

Salivary cortisol and cortisone in healthy children and young people

Dliso, S., Park, J., Jones, L., Bright, O., Shantsila, A., Hawcutt, D., . . . Blair, J. (n.d.). Salivary cortisol and cortisone in healthy children and young people. Endocrine Abstracts. doi:10.1530/endoabs.85.oc5.7

DOI
10.1530/endoabs.85.oc5.7
Journal article

Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study

Vink, E., Davis, C., MacLean, A., Pascall, D., McDonald, S. E., Gunson, R., . . . Ho, A. (2022). Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study. OPEN FORUM INFECTIOUS DISEASES, 9(11). doi:10.1093/ofid/ofac531

DOI
10.1093/ofid/ofac531
Journal article

Outcomes of the low dose short Synacthen test in infancy

Park, J., Jones, L., Dharmaraj, P., Senniappan, S., Morgan, C., Hawcutt, D., & Blair, J. (2022). Outcomes of the low dose short Synacthen test in infancy. In HORMONE RESEARCH IN PAEDIATRICS Vol. 95 (pp. 117). Retrieved from https://www.webofscience.com/

Conference Paper

199 Challenges in identification of hypertension in children and young people with Turner Syndrome

Jones, L., Park, J., Blair, J., Hawcutt, D., Shantsila, A., & Lip, G. Y. H. (2022). 199 Challenges in identification of hypertension in children and young people with Turner Syndrome. In British Society of Paediatric Endocrinology and Diabetes (pp. A271.1-A271). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.438

DOI
10.1136/archdischild-2022-rcpch.438
Conference Paper

430 Measuring blood pressure in children and adolescents: 20 years of change

Jones, L., Park, J., Blair, J., Hawcutt, D., Shantsila, A., & Lip, G. Y. H. (2022). 430 Measuring blood pressure in children and adolescents: 20 years of change. In British Association of General Paediatrics (pp. A108.2-A109). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.176

DOI
10.1136/archdischild-2022-rcpch.176
Conference Paper

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

Horby, P. W., Emberson, J. R., Mafham, M., Campbell, M., Peto, L., Pessoa-Amorim, G., . . . Landray, M. J. (2022). Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis. LANCET, 400(10349), 359-368. Retrieved from https://www.webofscience.com/

Journal article

Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission

Relph, K. A., Russell, C. D., Fairfield, C. J., Turtle, L., de Silva, T. I., Siggins, M. K., . . . Young, P. (2022). Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission. Open Forum Infectious Diseases, 9(5). doi:10.1093/ofid/ofac179

DOI
10.1093/ofid/ofac179
Journal article

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial

Bradbury, C. A., Lawler, P. R., Stanworth, S. J., McVerry, B. J., McQuilten, Z., Higgins, A. M., . . . Gordon, A. C. (2022). Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 327(13), 1247-1259. doi:10.1001/jama.2022.2910

DOI
10.1001/jama.2022.2910
Journal article

Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.

Hammitt, L. L., Dagan, R., Yuan, Y., Baca Cots, M., Bosheva, M., Madhi, S. A., . . . MELODY Study Group. (2022). Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.. The New England journal of medicine, 386(9), 837-846. doi:10.1056/nejmoa2110275

DOI
10.1056/nejmoa2110275
Journal article

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Horby, P. W., Mafham, M., Peto, L., Campbell, M., Pessoa-Amorim, G., Spata, E., . . . Landray, M. J. (2022). Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 399(10325), 665-676. Retrieved from https://www.webofscience.com/

DOI
10.1016/s0140-6736(22)00163-5
Journal article

Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol

Knight, S. R., Gupta, R. K., Ho, A., Pius, R., Buchan, I., Carson, G., . . . Harrison, E. M. (2022). Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. THORAX, 77(6), 606-615. doi:10.1136/thoraxjnl-2021-217629

DOI
10.1136/thoraxjnl-2021-217629
Journal article

2021

Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity

Fallerini, C., Picchiotti, N., Baldassarri, M., Zguro, K., Daga, S., Fava, F., . . . Furini, S. (2021). Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity.. Human genetics, 141(1), 147-173. doi:10.1007/s00439-021-02397-7

DOI
10.1007/s00439-021-02397-7
Journal article

Beclometasone but not fluticasone modulates PDGFD expression in the H295R adrenal cell line.

DOI
10.21203/rs.3.rs-1152078/v1
Preprint

Deprescribing montelukast in children with asthma: A systematic review

Dixon, E., King, C., Lilley, A., Sinha, I., & Hawcutt, D. (2021). Deprescribing montelukast in children with asthma: A systematic review. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 4891). Retrieved from https://www.webofscience.com/

Conference Paper

Glucose regulation and cardiovascular health in children and young people (CYP) with primary adrenal insufficiency: preliminary data (GRACE study)

Park, J., Hawcutt, D., Shantsila, A., Lip, G., & Blair, J. (n.d.). Glucose regulation and cardiovascular health in children and young people (CYP) with primary adrenal insufficiency: preliminary data (GRACE study). Endocrine Abstracts. doi:10.1530/endoabs.78.p2

DOI
10.1530/endoabs.78.p2
Journal article

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia

Bielicki, J. A., Stohr, W., Barratt, S., Dunn, D., Naufal, N., Roland, D., . . . Sharland, M. (2021). Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia The CAP-IT Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(17), 1713-1724. doi:10.1001/jama.2021.17843

DOI
10.1001/jama.2021.17843
Journal article

Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol

Sigfrid, L., Drake, T. M., Pauley, E., Jesudason, E. C., Olliaro, P., Lim, W. S., . . . Scott, J. T. (2021). Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. LANCET REGIONAL HEALTH-EUROPE, 8. doi:10.1016/j.lanepe.2021.100186

DOI
10.1016/j.lanepe.2021.100186
Journal article

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study

Russell, C. D., Fairfield, C. J., Drake, T. M., Turtle, L., Seaton, R. A., Wootton, D. G., . . . Ho, A. (2021). Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study. LANCET MICROBE, 2(8), E354-E365. doi:10.1016/S2666-5247(21)00090-2

DOI
10.1016/S2666-5247(21)00090-2
Journal article

ADRB2 Haplotypes and Asthma Exacerbations in Children and Young Adults: An Individual Participant Data Meta-Analysis.

Karimi, L., Vijverberg, S. J., Engelkes, M., Hernandez-Pacheco, N., Farzan, N., Soares, P., . . . PiCA, SysPharmPedia consortia. (2021). ADRB2 Haplotypes and Asthma Exacerbations in Children and Young Adults: An Individual Participant Data Meta-Analysis.. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. doi:10.1111/cea.13965

DOI
10.1111/cea.13965
Journal article

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

Drake, T. M., Riad, A. M., Fairfield, C. J., Egan, C., Knight, S. R., Pius, R., . . . Semple, M. G. (2021). Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. LANCET, 398(10296), 223-237. Retrieved from https://www.webofscience.com/

Journal article

Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

Docherty, A., Mulholland, R., Lone, N. I., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . Semple, M. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 773-785. doi:10.1016/S2213-2600(21)00175-2

DOI
10.1016/S2213-2600(21)00175-2
Journal article

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study

Drake, T. M., Fairfield, C. J., Pius, R., Knight, S. R., Norman, L., Girvan, M., . . . ISARIC4C Investigators. (2021). Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study.. The Lancet. Rheumatology, 3(7), e498-e506. doi:10.1016/s2665-9913(21)00104-1

DOI
10.1016/s2665-9913(21)00104-1
Journal article

Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID-19: Analysis of the ISARIC CCP-UK Cohort

Yates, T., Zaccardi, F., Islam, N., Razieh, C., Gillies, C. L., Lawson, C. A., . . . Khunti, K. (2021). Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID-19: Analysis of the ISARIC CCP-UK Cohort. OBESITY, 29(7), 1223-1230. doi:10.1002/oby.23178

DOI
10.1002/oby.23178
Journal article

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

Bloom, C. I., Drake, T. M., Docherty, A. B., Lipworth, B. J., Johnston, S. L., Nguyen-Van-Tam, J. S., . . . Openshaw, P. J. M. (2021). Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 699-711. doi:10.1016/S2213-2600(21)00013-8

DOI
10.1016/S2213-2600(21)00013-8
Journal article

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

Gupta, R. K., Harrison, E. M., Ho, A., Docherty, A. B., Knight, S. R., van Smeden, M., . . . Noursadeghi, M. (2021). Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study. LANCET RESPIRATORY MEDICINE, 9(4), 349-359. doi:10.1016/S2213-2600(20)30559-2

DOI
10.1016/S2213-2600(20)30559-2
Journal article

Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol

Sigfrid, L., Drake, T., Pauley, E., Jesudason, E., Olliaro, P., Lim, W. S., . . . ISARIC4C investigators. (2021). Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. doi:10.1101/2021.03.18.21253888

DOI
10.1101/2021.03.18.21253888
Journal article

Erratum to “COVID-19 in children: what did we learn from the first waveˮ [Paediatr Child Health 30 (2020) 438–443/1496]

Bogiatzopoulou, A., Mayberry, H., Hawcutt, D. B., Whittaker, E., Munro, A., Roland, D., . . . Harwood, R. (2021). Erratum to "COVID-19 in children: what did we learn from the first waveˮ [Paediatr Child Health 30 (2020) 438-443/1496].. Paediatrics and child health, 31(3), 128. doi:10.1016/j.paed.2021.01.001

DOI
10.1016/j.paed.2021.01.001
Journal article

Dexamethasone in Hospitalized Patients with Covid-19

Wootton, D., & The RECOVERY Collaborative Group. (2021). Dexamethasone in Hospitalized Patients with Covid-19. New England Journal of Medicine, 384(8), 693-704. doi:10.1056/nejmoa2021436

DOI
10.1056/nejmoa2021436
Journal article

2020

Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020

Thompson, C. P., Grayson, N. E., Paton, R. S., Bolton, J. S., Lourenco, J., Penman, B. S., . . . Simmonds, P. (2020). Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020. EUROSURVEILLANCE, 25(42), 33-41. doi:10.2807/1560-7917.ES.2020.25.42.2000685

DOI
10.2807/1560-7917.ES.2020.25.42.2000685
Journal article

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Angus, D. C., Derde, L., Al-Beidh, F., Annane, D., Arabi, Y., Beane, A., . . . Summers, C. (2020). Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.. JAMA, 324(13), 1317-1329. doi:10.1001/jama.2020.17022

DOI
10.1001/jama.2020.17022
Journal article

COVID-19 in children: what did we learn from the first wave?

Bogiatzopoulou, A., Mayberry, H., Hawcutt, D. B., Whittaker, E., Munro, A., Roland, D., . . . Harwood, R. (2020). COVID-19 in children: what did we learn from the first wave?. Paediatrics and child health. doi:10.1016/j.paed.2020.09.005

DOI
10.1016/j.paed.2020.09.005
Journal article

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.

Knight, S. R., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T. M., . . . ISARIC4C investigators. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.. BMJ: British Medical Journal, 370. doi:10.1136/bmj.m3339

DOI
10.1136/bmj.m3339
Journal article

A systematic review of the impact of food insecurity on the risk of developing asthma, or having poor asthma control, in childhood

Mahmood, S., Cheetham, S., Brown, L., Hawcutt, D., Lawrence, P., Mayell, S., . . . Sinha, I. (2020). A systematic review of the impact of food insecurity on the risk of developing asthma, or having poor asthma control, in childhood. In EUROPEAN RESPIRATORY JOURNAL Vol. 56. doi:10.1183/13993003.congress-2020.3510

DOI
10.1183/13993003.congress-2020.3510
Conference Paper

Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study

Swann, O., Holden, K., Turtle, L., Pollock, L., Fairfield, C., Drake, T., . . . ISARIC Coronavirus Clinical Characterisation Consortium (ISARIC4C) Investigators. (2020). Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study. BMJ, 370. doi:10.1136/bmj.m3249

DOI
10.1136/bmj.m3249
Journal article

Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol (UK): a prospective observational study

Geretti, A., Stockdale, A., Kelly, S., Villa, G., Turtle, L., Semple, M., & Sabin, C. (2020). Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol (UK): a prospective observational study. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 23, 13-14. Retrieved from https://www.webofscience.com/

Journal article

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

Knight, S., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T., . . . Harrison, E. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. doi:10.1101/2020.07.30.20165464

DOI
10.1101/2020.07.30.20165464
Journal article

COVID-19 infection in children

Sinha, I. P., Harwood, R., Semple, M. G., Hawcutt, D. B., Thursfield, R., Narayan, O., . . . Southern, K. W. (2020). COVID-19 infection in children. LANCET RESPIRATORY MEDICINE, 8(5), 446-447. Retrieved from https://www.webofscience.com/

DOI
10.1016/s2213-2600(20)30152-1
Journal article

2019

Oral steroids for preschool children with acute wheeze: a systematic review and meta-analysis

Murphy, J., King, C., Kapitein, B., Fernandes, R., Lilley, A., Messahel, S., . . . Sinha, I. (2019). Oral steroids for preschool children with acute wheeze: a systematic review and meta-analysis. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.OA4941

DOI
10.1183/13993003.congress-2019.OA4941
Conference Paper

The effects of ambient air pollution on the risk of hospitalisation with acute respiratory illnesses in children: an overview of systematic reviews

King, C., Surace, A. E., Jeffers, G., Hawcutt, D., & Sinha, I. (2019). The effects of ambient air pollution on the risk of hospitalisation with acute respiratory illnesses in children: an overview of systematic reviews. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA2834

DOI
10.1183/13993003.congress-2019.PA2834
Conference Paper

Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study

DB, H., B, F., DF, C., AL, J., P, Y., N, W., . . . M, P. (n.d.). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. Yearbook of Paediatric Endocrinology. doi:10.1530/ey.16.8.11

DOI
10.1530/ey.16.8.11
Journal article

P44 Type 2 diabetes mellitus in children: non-insulin medication, where are we up to?

Austin, R., Paul, P., & Hawcutt, D. (2019). P44 Type 2 diabetes mellitus in children: non-insulin medication, where are we up to?. Archives of Disease in Childhood, 104(6), e35.2-e35. doi:10.1136/archdischild-2019-esdppp.82

DOI
10.1136/archdischild-2019-esdppp.82
Journal article

P45 The acceptability of using genetic information to guide treatment of asthma to children, young people, and parents (pilot study)

King, C., Bracken, L., McDonough, E., Pirmohamed, M., Peak, M., & Hawcutt, D. (2019). P45 The acceptability of using genetic information to guide treatment of asthma to children, young people, and parents (pilot study). Archives of Disease in Childhood, 104(6), e35.3-e36. doi:10.1136/archdischild-2019-esdppp.83

DOI
10.1136/archdischild-2019-esdppp.83
Journal article

P46 Spontaneous reporting of suspected adverse drug reactions by children and young people: past, present and future

King, C., Bhoombla, N., Clarke, J., Morgan, V., Preston, J., Ainsworth, J., . . . Hawcutt, D. (2019). P46 Spontaneous reporting of suspected adverse drug reactions by children and young people: past, present and future. Archives of Disease in Childhood, 104(6), e36.1-e36. doi:10.1136/archdischild-2019-esdppp.84

DOI
10.1136/archdischild-2019-esdppp.84
Journal article

P69 Pharmacokinetics of a continuous infusion of piperacillin/tazobactam to children using an elastomeric pump (POPPET Study): pilot data from double lumen central lines

Moss, J., Price, V., Paulus, S., Ramos-Martin, V., Melaine, A., Evans, E., . . . Pizer, B. (2019). P69 Pharmacokinetics of a continuous infusion of piperacillin/tazobactam to children using an elastomeric pump (POPPET Study): pilot data from double lumen central lines. Archives of Disease in Childhood, 104(6), e45.3-e46. doi:10.1136/archdischild-2019-esdppp.107

DOI
10.1136/archdischild-2019-esdppp.107
Journal article

P70 Identifying and managing problematic polypharmacy in children and young people?

Moss, J., Austin, R., & Hawcutt, D. (2019). P70 Identifying and managing problematic polypharmacy in children and young people?. Archives of Disease in Childhood, 104(6), e46.1-e46. doi:10.1136/archdischild-2019-esdppp.108

DOI
10.1136/archdischild-2019-esdppp.108
Journal article

G76(P) Paediatric patient portals: variations in perception of benefit and risk amongst key stakeholders

Neame, M., Thompson, H., Sinha, I. P., Hawcutt, D., & Barnes, N. (2019). G76(P) Paediatric patient portals: variations in perception of benefit and risk amongst key stakeholders. In QUALITY IMPROVEMENT; EMBEDDING A CULTURE OF QUALITY IMPROVEMENT (pp. A31.3-A32). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2019-rcpch.75

DOI
10.1136/archdischild-2019-rcpch.75
Conference Paper

2018

Identification of a novel locus associated with asthma treatment response with inhaled corticosteroids in African-admixed children

Hernandez-Pacheco, N., Farzan, N., Vijverberg, S., Francis, B., Schieck, M., Pirmohamed, M., . . . Pino-Yanes, M. (2018). Identification of a novel locus associated with asthma treatment response with inhaled corticosteroids in African-admixed children. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 26 (pp. 693-694). Retrieved from https://www.webofscience.com/

Conference Paper

Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study

DB, H., B, F., DF, C., AL, J., P, Y., N, W., . . . M, P. (n.d.). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. Yearbook of Paediatric Endocrinology. doi:10.1530/ey.15.8.6

DOI
10.1530/ey.15.8.6
Journal article

Solving the problem of dose optimisation of children’s medicines

McWilliam, S., & Hawcutt, D. B. (2018). Solving the problem of dose optimisation of children’s medicines. Expert Review of Clinical Pharmacology, 11(3), 205-208. doi:10.1080/17512433.2018.1431528

DOI
10.1080/17512433.2018.1431528
Journal article

2017

O-24 Adrin 1 methodology study: adverse drug reactions in neonates: what are the best ways to evaluate suspected adverse drug reactions in neonates?

Roberts., Hawcutt., & Turner. (2017). O-24 Adrin 1 methodology study: adverse drug reactions in neonates: what are the best ways to evaluate suspected adverse drug reactions in neonates?. In Archives of Disease in Childhood Vol. 102 (pp. A11.2-A11). BMJ. doi:10.1136/archdischild-2017-esdppp.24

DOI
10.1136/archdischild-2017-esdppp.24
Conference Paper

Precision dosing to reduce ADRs in children

Hawcutt, D. (2017). Precision dosing to reduce ADRs in children. In DRUG SAFETY Vol. 40 (pp. 1040-1041). Retrieved from https://www.webofscience.com/

Conference Paper

Genome-wide association study of asthma exacerbations in European children treated with inhaled corticosteroids

Vijverberg, S. J. H., Hernandez-Pacheco, N., Farzan, N., Francis, B., Flores, C., Schieck, M., . . . Maitland-Van der Zee, A. -H. (2017). Genome-wide association study of asthma exacerbations in European children treated with inhaled corticosteroids. In EUROPEAN RESPIRATORY JOURNAL Vol. 50. doi:10.1183/1393003.congress-2017.PA1817

DOI
10.1183/1393003.congress-2017.PA1817
Conference Paper

17q21 gene variation increases the risk of exacerbations in asthmatic children treated with inhaled corticosteroids: A meta-analysis in the multi-ethnic pica consortium

Farzan, N., Vijverberg, S. J., Hernandez-Pacheco, N., Berce, V., Burchard, E. G., Canino, G., . . . Maitland-Van der Zee, A. H. (2017). 17q21 gene variation increases the risk of exacerbations in asthmatic children treated with inhaled corticosteroids: A meta-analysis in the multi-ethnic pica consortium. In ALLERGY Vol. 72 (pp. 269-270). Retrieved from https://www.webofscience.com/

Conference Paper

Growth hormone prescribing and initial BMI SDS: Increased biochemical adverse effects and costs in obese children without additional gain in height

Hawcutt, D. B., Bellis, J., Price, V., Povall, A., Newland, P., Richardson, P., . . . Blair, J. (2017). Growth hormone prescribing and initial BMI SDS: Increased biochemical adverse effects and costs in obese children without additional gain in height. PLoS One, 12(7). doi:10.1371/journal.pone.0181567

DOI
10.1371/journal.pone.0181567
Journal article

Optimising the use of medicines to reduce acute kidney injury in children and babies

Oni, L., Hawcutt, D. B., Turner, M. A., Beresford, M. W., McWilliam, S., Barton, C., . . . Antoine, D. J. (2017). Optimising the use of medicines to reduce acute kidney injury in children and babies. Pharmacology and Therapeutics, 174, 55-62. doi:10.1016/j.pharmthera.2017.02.018

DOI
10.1016/j.pharmthera.2017.02.018
Journal article

17q21 Gene Variance Increases The Risk Of Exacerbations In Asthmatic Children Treated With Inhaled Corticosteroids: A Meta-Analysis In The Pica Consortium

Farzan, N., Vijverberg, S., Hernandez-Pacheco, N., Berce, V., Burchard, E. G., Canino, G., . . . Maitland-van Der Zee, A. -H. (2017). 17q21 Gene Variance Increases The Risk Of Exacerbations In Asthmatic Children Treated With Inhaled Corticosteroids: A Meta-Analysis In The Pica Consortium. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 195. Washington DC. Retrieved from http://gateway.webofknowledge.com/

Conference Paper

2016

Home Urine Sampling as a Research Methodology in Longitudinal Biological Research Studies in Children with Cancer - Patient, Parent and Scientific Perspectives

Cooper, K., Barton, C., Hemsworth, S., Hincks, E., Hawcutt, D., & Pizer, B. (2016). Home Urine Sampling as a Research Methodology in Longitudinal Biological Research Studies in Children with Cancer - Patient, Parent and Scientific Perspectives. In PEDIATRIC BLOOD & CANCER Vol. 63 (pp. S220-S221). Retrieved from https://www.webofscience.com/

Conference Paper

Defining uncontrolled childhood asthma in the global PiCA consortium

Farzan, N., Vijverberg, S. J., Andiappan, A., Palmer, C. J., Tantisira, K. G., Duijts, L., . . . Maitland-van der Zee, A. H. (2016). Defining uncontrolled childhood asthma in the global PiCA consortium. In ALLERGY Vol. 71 (pp. 53). Retrieved from https://www.webofscience.com/

Conference Paper

Adrenal responses to a low-dose short synacthen test in children with asthma.

Hawcutt, D. B., Jorgensen, A. L., Wallin, N., Thompson, B., Peak, M., Lacy, D., . . . Smyth, R. L. (2016). Adrenal responses to a low-dose short synacthen test in children with asthma (vol 82, pg 648, 2015). CLINICAL ENDOCRINOLOGY, 84(5), 793. doi:10.1111/cen.13069

DOI
10.1111/cen.13069
Journal article

The Evidence for Intravenous Theophylline Levels between 10-20mg/L in Children Suffering an Acute Exacerbation of Asthma: A Systematic Review

Cooney., sinha., & Hawcutt, D. B. (2016). The Evidence for Intravenous Theophylline Levels between 10-20mg/L in Children Suffering an Acute Exacerbation of Asthma: A Systematic Review. PLoS ONE. doi:10.1371/journal.pone.0153877

DOI
10.1371/journal.pone.0153877
Journal article

SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR NEONATES AND INFANTS IN THE UK 2001–2010

Hawcutt, D., Maqsood, H., Gomberg, S., Riordan, A., & Turner, M. (2016). SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR NEONATES AND INFANTS IN THE UK 2001–2010. Archives of Disease in Childhood, 101(1), e1.43-e1. doi:10.1136/archdischild-2015-310148.48

DOI
10.1136/archdischild-2015-310148.48
Journal article

SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR TRANSPLACENTAL AND TRANSMAMMARY ROUTES IN THOSE ≤1 YEAR IN THE UK 2001–2010

Russell, N. -J., Turner, M., & Hawcutt, D. (2016). SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR TRANSPLACENTAL AND TRANSMAMMARY ROUTES IN THOSE ≤1 YEAR IN THE UK 2001–2010. Archives of Disease in Childhood, 101(1), e1.21-e1. doi:10.1136/archdischild-2015-310148.28

DOI
10.1136/archdischild-2015-310148.28
Journal article

2015

Between patient and inter-time point variability in salivary cortisone: cortisol ratios

Park, J., Lancaster, G., Titman, A., Peak, M., Newlands, P., Collingwood, C., . . . Blair, J. (n.d.). Between patient and inter-time point variability in salivary cortisone: cortisol ratios. Endocrine Abstracts. doi:10.1530/endoabs.39.ep2

DOI
10.1530/endoabs.39.ep2
Journal article

ST13 polymorphisms and their effect on exacerbations in steroid‐treated asthmatic children and young adults

Vijverberg, S. J. H., Koster, E. S., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., . . . Maitland-van der Zee, A. H. (2015). ST13 polymorphisms and their effect on exacerbations in steroid‐treated asthmatic children and young adults. Clinical and Experimental Allergy, 45(6), 1051-1059. doi:10.1111/cea.12492

DOI
10.1111/cea.12492
Journal article

ACUTE KIDNEY INJURY IN PAEDIATRIC ONCOLOGY PATIENTS RECEIVING CISPLATIN

Barton, C., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2015). ACUTE KIDNEY INJURY IN PAEDIATRIC ONCOLOGY PATIENTS RECEIVING CISPLATIN. PEDIATRIC BLOOD & CANCER, 62, S302-S303. Retrieved from https://www.webofscience.com/

Journal article

Implementation of a clinical protocol for measuring early morning salivary cortisol and cortisone, as a screening test for asthmatics at high risk of adrenal crisis

Trinick, R., Doyle, C., McNamara, P., Hawcutt, D., Kelly, E., Worrall, V., & Blair, J. (2015). Implementation of a clinical protocol for measuring early morning salivary cortisol and cortisone, as a screening test for asthmatics at high risk of adrenal crisis. In CLINICAL AND EXPERIMENTAL ALLERGY Vol. 45 (pp. 1908). Retrieved from https://www.webofscience.com/

Conference Paper

MARKERS OF TUBULAR RENAL INJURY IN CHILDREN WITH CANCER RECEIVING CISPLATIN AND/OR IFOSFAMIDE

Barton, C., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2015). MARKERS OF TUBULAR RENAL INJURY IN CHILDREN WITH CANCER RECEIVING CISPLATIN AND/OR IFOSFAMIDE. PEDIATRIC BLOOD & CANCER, 62, S302. Retrieved from https://www.webofscience.com/

Journal article

2014

Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.

Hawcutt, D., Ghani, A., Sutton, L., Jorgensen, A., Zhang, E., Murray, M., . . . Pirmohamed, M. (2014). Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.. The Pharmacogenomics Journal, 14(6), 542-548. doi:10.1038/tpj.2014.31

DOI
10.1038/tpj.2014.31
Journal article

G365 Medical management of neuropathic pain in complex regional pain syndromes

Hawcutt, D., Whitby, T., & Cleary, G. (2014). G365 Medical management of neuropathic pain in complex regional pain syndromes. Archives of Disease in Childhood, 99(Suppl 1), A150-A151. doi:10.1136/archdischild-2014-306237.348

DOI
10.1136/archdischild-2014-306237.348
Journal article

G409(P) National audit of analgesia post tonsillectomy

O'Connor, O., Hawcutt, D., & Donne, A. (2014). G409(P) National audit of analgesia post tonsillectomy. Archives of Disease in Childhood, 99(Suppl 1), A172. doi:10.1136/archdischild-2014-306237.390

DOI
10.1136/archdischild-2014-306237.390
Journal article

A randomized trial of hyperglycemic control in pediatric intensive care.

Macrae, D., Grieve, R., Allen, E., Sadique, Z., Morris, K., Pappachan, J., . . . CHiP Investigators. (2014). A randomized trial of hyperglycemic control in pediatric intensive care.. The New England journal of medicine, 370(2), 107-118. doi:10.1056/nejmoa1302564

DOI
10.1056/nejmoa1302564
Journal article

Assessing the reliability of exome sequencing to detect the filaggrin null mutations R501X and 2282del4

Thompson, B., Hawcutt, D., Carr, D., Bloch, K., Swale, A., Smyth, R., & Pirmohamed, M. (2014). Assessing the reliability of exome sequencing to detect the filaggrin null mutations R501X and 2282del4. In BRITISH JOURNAL OF DERMATOLOGY Vol. 171 (pp. 115-116). Retrieved from https://www.webofscience.com/

Conference Paper

Early morning salivary cortisol and cortisone, and adrenal responses to a simplified low-dose short Synacthen test in children with asthma

Blair, J., Lancaster, G., Titman, A., Peak, M., Newlands, P., Collingwood, C., . . . Couriel, J. (2014). Early morning salivary cortisol and cortisone, and adrenal responses to a simplified low-dose short Synacthen test in children with asthma. CLINICAL ENDOCRINOLOGY, 80(3), 376-383. doi:10.1111/cen.12302

DOI
10.1111/cen.12302
Journal article

2013

Paediatric pharmacogenomics: an overview

Hawcutt, D. B., Thompson, B., Smyth, R. L., & Pirmohamed, M. (2013). Paediatric pharmacogenomics: an overview. Archives of Disease in Childhood, 98(3), 232-237. doi:10.1136/archdischild-2012-302852

DOI
10.1136/archdischild-2012-302852
Journal article

2012

VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN

Thompson, B., Hawcutt, D. B., Carr, D. F., Jorgensen, A. L., Smyth, R. L., & Pirmohamed, M. (2012). VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN. THORAX, 67, A17. doi:10.1136/thoraxjnl-2012-202678.037

DOI
10.1136/thoraxjnl-2012-202678.037
Journal article

Reported paediatric adverse drug reactions in the UK 2000-2009

Hawcutt, D. B., Mainie, P., Riordan, A., Smyth, R. L., & Pirmohamed, M. (2012). Reported paediatric adverse drug reactions in the UK 2000-2009. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 73(3), 437-446. doi:10.1111/j.1365-2125.2011.04113.x

DOI
10.1111/j.1365-2125.2011.04113.x
Journal article

Acute kidney injury in paediatric cancer patients receiving cisplatin

Barton, C., Oates, A., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2012). Acute kidney injury in paediatric cancer patients receiving cisplatin. Journal of the Royal College of Physicians Edinburgh, 42(Sup, 36�50.

Journal article

Reported Paediatric Adverse Drug Reactions in the UK 2000-2009

Hawcutt, D., Mainie, P., Andrew, R., Smyth, R. L., & Pirmohamed, M. (2012). Reported Paediatric Adverse Drug Reactions in the UK 2000-2009. British Journal of Clinical Pharmacology, 73(3), 437-446.

Journal article

2011

Treatment of neonatal sepsis with intravenous immune globulin.

INIS Collaborative Group., Brocklehurst, P., Farrell, B., King, A., Juszczak, E., Darlow, B., . . . Tarnow-Mordi, W. (2011). Treatment of neonatal sepsis with intravenous immune globulin.. The New England journal of medicine, 365(13), 1201-1211. doi:10.1056/nejmoa1100441

DOI
10.1056/nejmoa1100441
Journal article

Serum phenytoin concentrations in paediatric patients following intravenous loading

Hawcutt, D. B., Sampath, S., Timmis, A., Newland, V., Newland, P., & Appleton, R. (2011). Serum phenytoin concentrations in paediatric patients following intravenous loading. ARCHIVES OF DISEASE IN CHILDHOOD, 96(9), 883-884. doi:10.1136/adc.2011.215269

DOI
10.1136/adc.2011.215269
Journal article

'Lest we forget ...'

Mainie, P., & Hawcutt, D. (2011). 'Lest we forget ...'. ARCHIVES OF DISEASE IN CHILDHOOD, 96(7), 699. doi:10.1136/adc.2010.208363

DOI
10.1136/adc.2010.208363
Journal article

Twin-twin confusion syndrome: Blood chimerism in opposite sex dizygotic twins

Hawcutt, D., Hammond, B., Sibbring, J., Gokhale, D., Ellis, I., Bricker, L., & Subhedar, N. (2011). Twin-twin confusion syndrome: Blood chimerism in opposite sex dizygotic twins. JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 31(5), 446-448. doi:10.3109/01443615.2011.570813

DOI
10.3109/01443615.2011.570813
Journal article

Adverse drug reactions in children: reports to the UK yellow card scheme 2000-2009

Hawcutt, D. B., Mainie, P., Appleton, R., Smyth, R., & Pirmohamed, M. (2011). Adverse drug reactions in children: reports to the UK yellow card scheme 2000-2009. Archives of Disease in Childhood, 96(Supplement 1), A57. doi:10.1136/adc.2011.212563.130

DOI
10.1136/adc.2011.212563.130
Journal article

"Lest we forget" Letter

Mainie, P., & Hawcutt, D. B. (2011). "Lest we forget" Letter. Archives of Disease in Childhood, 96, 699.

Journal article

Reported Paediatric Adverse Drug Reactions in the UK 2000-2009

Hawcutt, D. B., Mainie, P., Appleton, R., Smyth, R. L., & Pirmohamed, M. (2011). Reported Paediatric Adverse Drug Reactions in the UK 2000-2009. Archives of Disease in Childhood, 96, A5.

Journal article

Serum Levels of Phenytoin in Paediatric Patients following an 18mg/kg Intravenous Loading Dose.

Hawcutt, D. B., Sampath, S., Timmis, A., Newland, V., Newland, P., & Appleton, R. (2011). Serum Levels of Phenytoin in Paediatric Patients following an 18mg/kg Intravenous Loading Dose.. Archives of Disease in Childhood, 96(9), 883-884.

Journal article

Steroid dose, age and gender affect adrenal responses to a low dose short Synacthen test in children with asthma

Hawcutt, D. B., Jorgensen, A. L., Gardner, C., Peak, M., Couriel, J., Lacy, D., . . . Blair, J. (2011). Steroid dose, age and gender affect adrenal responses to a low dose short Synacthen test in children with asthma. Endocrine Abstracts, 27, 32.

Journal article

Sulthiame in refractory paediatric epilepsies: An experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit

Swiderska, N., Hawcutt, D., Eaton, V., Stockton, F., Kumar, R., Kneen, R., & Appleton, R. (2011). Sulthiame in refractory paediatric epilepsies: An experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 20(10), 805-808. doi:10.1016/j.seizure.2011.08.006

DOI
10.1016/j.seizure.2011.08.006
Journal article

2010

USE OF STEROIDS IN INOTROPE RESISTANT SEPSIS AND AT EXTUBATION IN UK PAEDIATRIC INTENSIVE CARE UNITS - TELEPHONE AUDIT

Hawcutt, D., Sharpe, J., & Parkins, K. (2010). USE OF STEROIDS IN INOTROPE RESISTANT SEPSIS AND AT EXTUBATION IN UK PAEDIATRIC INTENSIVE CARE UNITS - TELEPHONE AUDIT. PEDIATRIC RESEARCH, 68, 626-627. doi:10.1203/00006450-201011001-01265

DOI
10.1203/00006450-201011001-01265
Journal article

Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates

Hawcutt, D. B., Rose, A. C., Fuerst-Recktenwald, S., Nunn, T., & Turner, M. A. (2010). Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates. In GUIDE TO PAEDIATRIC DRUG DEVELOPMENT AND CLINICAL RESEARCH (pp. 97-110). Retrieved from https://www.webofscience.com/

Chapter

Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon (vol 135, pg 205, 2008)

Lindley, R. M., Hawcutt, D. B., Connell, M. G., & Almond, S. L. (2010). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon (vol 135, pg 205, 2008). GASTROENTEROLOGY, 138(2), 792. Retrieved from https://www.webofscience.com/

Journal article

MUCOSITIS PREVENTION: EFFICACY OF SUPERSATURATED CALCIUM AND PHOSPHATE SOLUTION IN HIGH RISK PAEDIATRIC ONCOLOGY PATIENTS

Hawcutt, D., Awogbemi, O., Bell, E., & McDowell, H. (2010). MUCOSITIS PREVENTION: EFFICACY OF SUPERSATURATED CALCIUM AND PHOSPHATE SOLUTION IN HIGH RISK PAEDIATRIC ONCOLOGY PATIENTS. PEDIATRIC BLOOD & CANCER, 55(5), 951. Retrieved from https://www.webofscience.com/

Journal article

Mucositis Prevention: Efficacy of Supersaturated Calcium and Phosphate Solution in High Risk Paediatric Oncology Patients

Hawcutt, D. B., Awogbemi, O., Bell, E., & McDowell, H. (2010). Mucositis Prevention: Efficacy of Supersaturated Calcium and Phosphate Solution in High Risk Paediatric Oncology Patients. Paediatric Blood and Cancer, 5(55), 951.

Journal article

Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates

Hawcutt, D. B., Rose, A. C., Fuerst-Recktenwald, S., Nunn, T., & Turner, M. A. (2010). Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates. In Guide to Paediatric Drug Development and Clinical Research (pp. 97-110). KARGER. doi:10.1159/000315578

DOI
10.1159/000315578
Chapter

Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates

Hawcutt, D. B., Rose, A. C., Fuerst-Rectenwald, S., Nunn, A. J., & Turner, M. A. (2010). Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates. In K. Rose, & J. van den Anker (Eds.), Guide to Paediatric Drug Development and Clinial Research (pp. 96-110). Basel: Karger.

Chapter

2009

Prioritising neonatal medicines research: UK Medicines for Children Research Network scoping survey

Turner, M. A., Lewis, S., Hawcutt, D. B., & Field, D. (2009). Prioritising neonatal medicines research: UK Medicines for Children Research Network scoping survey. BMC PEDIATRICS, 9. doi:10.1186/1471-2431-9-50

DOI
10.1186/1471-2431-9-50
Journal article

Properties of secondary and tertiary human enteric nervous system neurospheres

Lindley, R. M., Hawcutt, D. B., Connell, M. G., Edgar, D. H., & Kenny, S. E. (2009). Properties of secondary and tertiary human enteric nervous system neurospheres. JOURNAL OF PEDIATRIC SURGERY, 44(6), 1249-1256. doi:10.1016/j.jpedsurg.2009.02.048

DOI
10.1016/j.jpedsurg.2009.02.048
Journal article

Functional analysis of enteric nervous system progenitor cells

Edgar, D., Lindley, R., Hawcutt, D., Theocharatos, S., & Kenny, S. (2009). Functional analysis of enteric nervous system progenitor cells. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 21 (pp. XIII). Retrieved from https://www.webofscience.com/

Conference Paper

Functional analysis of enteric nervous system progenitor cells

Edgar, D. H., Lindley, R. M., Hawcutt, D. B., Theocharatos, S., & Kenny, S. E. (2009). Functional analysis of enteric nervous system progenitor cells. Neurogastroenterology and Motility, 2(21), XIII.

Journal article

2008

Drug development for children: How is pharma tackling an unmet need?

Hawcutt, D. B., & Smyth, R. L. (2008). Drug development for children: How is pharma tackling an unmet need?. In IDRUGS Vol. 11 (pp. 502-507). Retrieved from https://www.webofscience.com/

Conference Paper

Drug development for children: How is pharma tackling an unmet need?

Hawcutt, D. B., & Smyth, R. L. (2008). Drug development for children: How is pharma tackling an unmet need?. IDRUGS, 11(11), 502-507.

Journal article

One size does not fit all: getting drug doses right for children

Hawcutt, D. B., & Smyth, R. L. (2008). One size does not fit all: getting drug doses right for children. ARCHIVES OF DISEASE IN CHILDHOOD, 93(3), 190-191. doi:10.1136/adc.2007.127951

DOI
10.1136/adc.2007.127951
Journal article

Chapter 9: Advances towards the Development of a Stem Cell Therapy for Hirschsprung's Disease

Hawcutt, D. B., Lindley, R. M., Kenny, S. E., & Edgar, D. H. (2008). Chapter 9: Advances towards the Development of a Stem Cell Therapy for Hirschsprung's Disease. In Stem Cell Research Progress (pp. 137-157). New York: Nova Science Publishers.

Chapter

Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon

Lindley, R. M., Hawcutt, D. B., Connell, M. G., Almond, S. N., Vannucchi, M. -G., Faussone-Pellegrini, M. S., . . . Kenny, S. E. (2008). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon. GASTROENTEROLOGY, 135(1), 205-216. doi:10.1053/j.gastro.2008.03.035

DOI
10.1053/j.gastro.2008.03.035
Journal article

Paediatric Pharmacogenomics - Challenges and Opportunities. 2008; 2(1): 13-15

Hawcutt, D. B., & Pirmohamed, M. (2008). Paediatric Pharmacogenomics - Challenges and Opportunities. 2008; 2(1): 13-15. European Paediatrics, 2(1), 13-15.

Journal article

Points to consider when planning the collection of blood samples in clinical trials of investigational medicinal products.

Hawcutt, D. B., Rose, A. C., Nunn, T., & Turner, M. A. (2008). Points to consider when planning the collection of blood samples in clinical trials of investigational medicinal products.. Liverpool: Medicines for Children Research Network. Retrieved from http://ctuprod.liv.ac.uk/mcrnweb/images/mcrn_guide_for_blood_sampling_v1.0.pdf

Report

The New European Regulation on Paediatric Medicines: Regulatory Perspective

Hawcutt, D. B., & Smyth, R. L. (2008). The New European Regulation on Paediatric Medicines: Regulatory Perspective. Pediatric Drugs, 10(3), 143-146.

Journal article

2007

Advances towards the development of a stem cell therapy for Hirschsprung's disease

Hawcutt, D. B., Lindley, R. M., Kenny, S. E., & Edgar, D. H. (2007). Advances towards the development of a stem cell therapy for Hirschsprung's disease. Journal of Stem Cells, 2(2), 105-119.

Journal article

Advances towards a stem cell therapy for Hirschprung's disease

Hawcutt, D. L. R. K. S., & Edgar, D. H. (2007). Advances towards a stem cell therapy for Hirschprung's disease. Journal of Stem Cells, 2, 41-47.

Journal article

Functional rescue following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease occurs via Nitric Oxide signalling

Hawcutt, D. B., Lindley, R. M., Edgar, D. H., & Kenny, S. E. (2007). Functional rescue following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease occurs via Nitric Oxide signalling. Journal of Perinatology, 27, 626.

Journal article

Restoration of function following mouse and human enteric nervous system transplants into an <i>in vitro</i> model of Hirschsprung's disease

Hawcutt, D., Lindley, R., Edgar, D., & Kenny, S. (2007). Restoration of function following mouse and human enteric nervous system transplants into an <i>in vitro</i> model of Hirschsprung's disease. GASTROENTEROLOGY, 132(4), A577. Retrieved from https://www.webofscience.com/

Journal article

Restoration of normal function following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease

Hawcutt, D. B., Lindley, R. M., Edgar, D. H., & Kenny, S. E. (2007). Restoration of normal function following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease. Archives of Disease in Childhood, 92(Suppl), A4-A5.

Journal article

2005

Workload Implications Of Obesity In The Paediatric Outpatient Clinic

Hawcutt, D. B., Casson, D., Williams, S., & Blair, J. C. (2005). Workload Implications Of Obesity In The Paediatric Outpatient Clinic. Archives of Disease in Childhood, 90(Suppl), A14-A18.

Journal article