Publications
Selected publications
- Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study (Journal article - 2018)
- Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia. (Journal article - 2023)
- Factors Associated With Diabetic Ketoacidosis at Onset of Type 1 Diabetes Among Pediatric Patients: A Systematic Review. (Journal article - 2022)
- Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital (Journal article - 2022)
- Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium (Journal article - 2017)
- 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. (Journal article - 2018)
- <i>TPMT</i>, <i>COMT</i> and <i>ACYP2</i> genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity (Journal article - 2017)
- Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment (Journal article - 2016)
- Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression (Journal article - 2023)
- The readability of parent information leaflets in paediatric studies (Journal article - 2023)
2024
Improving safety of unlicenced liquid specials medicines in the UK.
Tse, Y., Dudley, J., Trivedi, A., Crook, J., Hawcutt, D. B., Tomlin, S., & Joint RCPCH/NPPG Medicines committee. (2024). Improving safety of unlicenced liquid specials medicines in the UK.. Archives of disease in childhood, archdischild-2024-327558. doi:10.1136/archdischild-2024-327558
Rapid differentiation of cystic fibrosis-related bacteria via reagentless atmospheric pressure photoionisation mass spectrometry.
Haworth-Duff, A., Smith, B. L., Sham, T. -T., Boisdon, C., Loughnane, P., Burnley, M., . . . Maher, S. (2024). Rapid differentiation of cystic fibrosis-related bacteria via reagentless atmospheric pressure photoionisation mass spectrometry.. Scientific reports, 14(1), 17067. doi:10.1038/s41598-024-66851-y
Urine metabolomics signature reveals novel determinants of adrenal suppression in children taking inhaled corticosteroids to control asthma symptoms.
Tran, D. T., Chen, Y., Zheng, Y., Hecker, J., Hawcutt, D. B., Pirmohamed, M., . . . Dahlin, A. (2024). Urine metabolomics signature reveals novel determinants of adrenal suppression in children taking inhaled corticosteroids to control asthma symptoms.. Immunity, inflammation and disease, 12(7), e1315. doi:10.1002/iid3.1315
Stratified analyses refine association between TLR7 rare variants and severe COVID-19.
Boos, J., van der Made, C. I., Ramakrishnan, G., Coughlan, E., Asselta, R., Löscher, B. -S., . . . Ludwig, K. U. (2024). Stratified analyses refine association between TLR7 rare variants and severe COVID-19.. HGG advances, 5(4), 100323. doi:10.1016/j.xhgg.2024.100323
The Impact of Malnutrition on the Developing Lung and Long-Term Lung Health: A Narrative Review of Global Literature.
Tharumakunarajah, R., Lee, A., Hawcutt, D. B., Harman, N. L., & Sinha, I. P. (2024). The Impact of Malnutrition on the Developing Lung and Long-Term Lung Health: A Narrative Review of Global Literature.. Pulmonary therapy. doi:10.1007/s41030-024-00257-z
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Liew, F., Efstathiou, C., Fontanella, S., Richardson, M., Saunders, R., Swieboda, D., . . . ISARIC investigators. (2024). Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.. Nature immunology, 25(4), 607-621. doi:10.1038/s41590-024-01778-0
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael, B. D., Dunai, C., Needham, E. J., Tharmaratnam, K., Williams, R., Huang, Y., . . . Menon, D. K. (2024). Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.. Nature communications, 15(1), 2918. doi:10.1038/s41467-024-47320-6
Assessing and further developing age-appropriate information for young people about reporting suspected adverse drug reactions.
Bioletti, L., Alder Hey Research Ambassadors., Woodward, C., Jadeja, M., & Hawcutt, D. B. (2024). Assessing and further developing age-appropriate information for young people about reporting suspected adverse drug reactions.. British journal of clinical pharmacology, 90(3), 863-870. doi:10.1111/bcp.15971
Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. (2024). Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.. The Lancet. Child & adolescent health, S2352-4642(23)00316-4. doi:10.1016/s2352-4642(23)00316-4
Impact of indoor environment on children's pulmonary health.
Murphy, J., Tharumakunarajah, R., Holden, K. A., King, C., Lee, A. R., Rose, K., . . . Sinha, I. P. (2024). Impact of indoor environment on children's pulmonary health.. Expert review of respiratory medicine, 1-11. doi:10.1080/17476348.2024.2307561
2023
Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19.
Sidhu, J. K., Siggins, M. K., Liew, F., Russell, C. D., Uruchurtu, A. S. S., Davis, C., . . . ISARIC4C investigators. (2023). Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19.. The Journal of infectious diseases, 230(1), e17-e29. doi:10.1093/infdis/jiad590
Delayed mucosal anti-viral responses despite robust peripheral inflammation in fatal COVID-19.
Sidhu, J. K., Siggins, M. K., Liew, F., Russell, C. D., Uruchurtu, A. S. S., Davis, C., . . . ISARIC4C investigators. (2023). Delayed mucosal anti-viral responses despite robust peripheral inflammation in fatal COVID-19.. The Journal of infectious diseases, jiad590. doi:10.1093/infdis/jiad590
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Michael, B. D., Dunai, C., Needham, E. J., Tharmaratnam, K., Williams, R., Huang, Y., . . . Menon, D. K. (2023). Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.. Nature communications, 14(1), 8487. doi:10.1038/s41467-023-42320-4
Diurnal salivary cortisol and cortisone concentrations in girls with Turner syndrome and healthy controls: a preliminary report.
Jones, L., Park, J., Dliso, S., Hawcutt, D., Shantsila, A., Lip, G. Y. H., & Blair, J. C. (2023). Diurnal salivary cortisol and cortisone concentrations in girls with Turner syndrome and healthy controls: a preliminary report.. Archives of disease in childhood, archdischild-2023-326270. doi:10.1136/archdischild-2023-326270
20 years on - the measurement of blood pressure and detection of hypertension in children and adolescents: a national descriptive survey
Jones, L., Park, J., Blair, J., Hawcutt, D. B. B., Lip, G. Y. H., & Shantsila, A. (2023). 20 years on - the measurement of blood pressure and detection of hypertension in children and adolescents: a national descriptive survey. JOURNAL OF HUMAN HYPERTENSION. doi:10.1038/s41371-023-00846-6
Correction: Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group.
Ramanan, A. V., Modi, N., de Wildt, S. N., & c4c Learning from COVID-19 Group. (2023). Correction: Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group.. Pediatric research, 94(6), 2121. doi:10.1038/s41390-023-02655-6
Laser-cutting: A novel alternative approach for point-of-care manufacturing of bespoke tablets.
Liu, Y., M Leonova, A., Royall, P. G., Abdillah Akbar, B. V. E. B., Cao, Z., Jones, S. A., . . . Alhnan, M. A. (2023). Laser-cutting: A novel alternative approach for point-of-care manufacturing of bespoke tablets.. International journal of pharmaceutics, 647, 123518. doi:10.1016/j.ijpharm.2023.123518
Female paediatric patients with epilepsy who continue to receive valproate in the UK.
Lang, L., Dunbar-Creasey, N., Kneen, R., Neely, L., & Hawcutt, D. B. (2023). Female paediatric patients with epilepsy who continue to receive valproate in the UK.. Archives of disease in childhood, archdischild-2023-326591. doi:10.1136/archdischild-2023-326591
Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators., Adhikari, N. K. J., Hashmi, M., Tirupakuzhi Vijayaraghavan, B. K., Haniffa, R., Beane, A., . . . Lamontagne, F. (2023). Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.. JAMA, 330(18), 1745-1759. doi:10.1001/jama.2023.21407
Participant perceptions and experiences of a novel community-based respiratory longitudinal sampling method in Liverpool, UK: A mixed methods feasibility study.
German, E. L., Nabwera, H. M., Robinson, R., Shiham, F., Liatsikos, K., Parry, C. M., . . . Nikolaou, E. (2023). Participant perceptions and experiences of a novel community-based respiratory longitudinal sampling method in Liverpool, UK: A mixed methods feasibility study.. PloS one, 18(11), e0294133. doi:10.1371/journal.pone.0294133
Assessing the use of minimally invasive self-sampling at home for long-term monitoring of the microbiota within UK families.
Nikolaou, E., German, E. L., Howard, A., Nabwera, H. M., Matope, A., Robinson, R., . . . Ferreira, D. M. (2023). Assessing the use of minimally invasive self-sampling at home for long-term monitoring of the microbiota within UK families.. Scientific reports, 13(1), 18201. doi:10.1038/s41598-023-45574-6
Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. (2023). Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.. The lancet. Diabetes & endocrinology, S2213-8587(23)00253-X. doi:10.1016/s2213-8587(23)00253-x
ATTITUDES OF CHILDREN AND YOUNG PEOPLE AND THEIR PARENTS TOWARDS POLYPHARMACY - PILOT STUDY
Moss, J., Rashed, A., Walker, L., & Hawcutt, D. (2023). ATTITUDES OF CHILDREN AND YOUNG PEOPLE AND THEIR PARENTS TOWARDS POLYPHARMACY - PILOT STUDY. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A11-A12). doi:10.1136/archdischild-2023-ESDPPP.34
DEPRESCRIBING LONG ACTING BETA2 AGONISTS IN CHILDREN AND ADOLESCENTS WITH STABLE ASTHMA: A SYSTEMATIC REVIEW
Drozdz, W., Sinha, I., & Hawcutt, D. (2023). DEPRESCRIBING LONG ACTING BETA2 AGONISTS IN CHILDREN AND ADOLESCENTS WITH STABLE ASTHMA: A SYSTEMATIC REVIEW. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A12-A13). doi:10.1136/archdischild-2023-ESDPPP.37
DEPRESCRIBING LONG ACTING BETA2 AGONISTS INCHILDREN AND ADOLESCENTS WITH STABLE ASTHMA:A SYSTEMATIC REVIEW
Drozdz, W., Sinha, I., & Hawcutt, D. (2023). DEPRESCRIBING LONG ACTING BETA2 AGONISTS INCHILDREN AND ADOLESCENTS WITH STABLE ASTHMA:A SYSTEMATIC REVIEW. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A12). doi:10.1136/archdischild-2023-ESDPPP.32
International Pediatric COVID-19 Severity Over the Course of the Pandemic
Zhu, Y., Almeida, F. J., Baillie, J. K., Bowen, A. C., Britton, P. N., Brizuela, M. E., . . . Short, K. R. (2023). International Pediatric COVID-19 Severity Over the Course of the Pandemic. JAMA PEDIATRICS. doi:10.1001/jamapediatrics.2023.3117
WHAT DOMAINS RELATED TO MEDICINES WERE MEASURED IN STUDIES OF BURDEN OF CARE FOR PAEDIATRIC PATIENTS? A SYSTEMATIC REVIEW
Thatparan, T., Marro, J., & Hawcutt, D. (2023). WHAT DOMAINS RELATED TO MEDICINES WERE MEASURED IN STUDIES OF BURDEN OF CARE FOR PAEDIATRIC PATIENTS? A SYSTEMATIC REVIEW. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A10). doi:10.1136/archdischild-2023-ESDPPP.29
WHAT IS KNOWN ABOUT THE PHARMACOLOGY OF INTRAMUSCULAR THERAPEUTICS IN DUCHENNE MUSCULAR DYSTROPHY? A SYSTEMATIC REVIEW
Roberts, E., Gan, J. Y., Hawcutt, D., & Spinty, S. (2023). WHAT IS KNOWN ABOUT THE PHARMACOLOGY OF INTRAMUSCULAR THERAPEUTICS IN DUCHENNE MUSCULAR DYSTROPHY? A SYSTEMATIC REVIEW. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A12). doi:10.1136/archdischild-2023-ESDPPP.33
WHAT IS KNOWN ABOUT THE PHARMACOLOGY OF INTRAMUSCULAR THERAPEUTICS IN DUCHENNE MUSCULAR DYSTROPHY? A SYSTEMATIC REVIEW
Roberts, E., Gan, J. Y., Hawcutt, D., & Spinty, S. (2023). WHAT IS KNOWN ABOUT THE PHARMACOLOGY OF INTRAMUSCULAR THERAPEUTICS IN DUCHENNE MUSCULAR DYSTROPHY? A SYSTEMATIC REVIEW. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A12). doi:10.1136/archdischild-2023-ESDPPP.35
Real time mapping of particulate matter (PM) concentrations and paediatric asthma emergency department (ED) visits
Holden, K., Lee, A., King, C., Olajide, O., Hawcutt, D., Higham, J., & Sinha, I. (2023). Real time mapping of particulate matter (PM) concentrations and paediatric asthma emergency department (ED) visits. In Paediatric asthma and allergy (pp. PA1621). European Respiratory Society. doi:10.1183/13993003.congress-2023.pa1621
Use of air purifiers in homes to improve asthma outcomes for children: a pilot study protocol
Holden, K., Lee, A., Hawcutt, D., & Sinha, I. (2023). Use of air purifiers in homes to improve asthma outcomes for children: a pilot study protocol. In Paediatric asthma and allergy (pp. PA5370). European Respiratory Society. doi:10.1183/13993003.congress-2023.pa5370
A second update on mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative. (2023). A second update on mapping the human genetic architecture of COVID-19.. Nature, 621(7977), E7-E26. doi:10.1038/s41586-023-06355-3
Emergency Diagnosis Made Easy: Matrix Removal and Analyte Enrichment from Raw Saliva using Paper-Arrow Mass Spectrometry
Zhou, Y., Sham, T. -T., Boisdon, C., Smith, B., Blair, J., Hawcutt, D., & Maher, S. (2023). Emergency Diagnosis Made Easy: Matrix Removal and Analyte Enrichment from Raw Saliva using Paper-Arrow Mass Spectrometry. The Analyst. doi:10.1039/d3an00850a
27 Risk factors of augmented renal clearance in critically ill children using iohexol clearance for renal function assessment
Thatparan, T., Marro, J., & Hawcutt, D. (2023). What domains related to medicines were measured in studies of burden of care for paediatric patients? A systematic review. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A10). doi:10.1136/archdischild-2023-ESDPPP.27
The readability of parent information leaflets in paediatric studies
Nash, E., Bickerstaff, M., Chetwynd, A. J. J., Hawcutt, D. B. B., & Oni, L. (2023). The readability of parent information leaflets in paediatric studies. PEDIATRIC RESEARCH, 94(3), 1166-1171. doi:10.1038/s41390-023-02608-z
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 (vol 617, pg 764, 2023)
Pairo-Castineira, E., Rawlik, K., Bretherick, A. D., Qi, T., Wu, Y., Nassiri, I., . . . Baillie, J. K. (2023). GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 (vol 617, pg 764, 2023). NATURE. doi:10.1038/s41586-023-06383-z
Improvement in medication safety amongst paediatric ward rounds - a systematic review.
King, C., Dudley, J., Mee, A., Tomlin, S., Tse, Y., Trivedi, A., & Hawcutt, D. (2023). Improvement in medication safety amongst paediatric ward rounds - a systematic review.. In BRITISH JOURNAL OF PHARMACOLOGY Vol. 180 (pp. 266-267). Retrieved from https://www.webofscience.com/
POINT PREVALENCE STUDY OF PAEDIATRIC POLYPHARMACY
Moss, J., Rashed, A., Jensen, J., Wilson, J., Walker, L., & Hawcutt, D. (2023). POINT PREVALENCE STUDY OF PAEDIATRIC POLYPHARMACY. In ARCHIVES OF DISEASE IN CHILDHOOD Vol. 108 (pp. A8). doi:10.1136/archdischild-2023-ESDPPP.25
31 The impact of paediatric dose range checking software
Rybka, E., Neame, M., Moss, J., Saez Dominguez, J., Gill, A., Barnes, N., & Hawcutt, D. (2023). 31 The impact of paediatric dose range checking software. Archives of Disease in Childhood, 108(6), A11.1-A11. doi:10.1136/archdischild-2023-esdppp.31
Participant perceptions and experiences of a novel community-based pilot respiratory longitudinal sampling method in Liverpool, UK
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
Pairo-Castineira, E., Rawlik, K., Bretherick, A. D., Qi, T., Wu, Y., Nassiri, I., . . . Baillie, J. K. (2023). GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19. NATURE, 617(7962), 764-+. doi:10.1038/s41586-023-06034-3
Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial
Horby, P. W., Emberson, J. R., Basnyat, B., Campbell, M., Peto, L., Pessoa-Amorim, G., . . . Landray, M. J. (2023). Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 401(10387), 1499-1507. doi:10.1016/S0140-6736(23)00510-X
Urinary Metabolite Signatures Are Associated With Low Cortisol Levels in Children Taking Inhaled Corticosteroids
Tran, D. T., Chen, Y., Hecker, J., Hawcutt, D. B., Pirmohamed, M., Lasky-Su, J. A., . . . Dahlin, A. (2023). Urinary Metabolite Signatures Are Associated With Low Cortisol Levels in Children Taking Inhaled Corticosteroids. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 207. Retrieved from https://www.webofscience.com/
Nirsevimab for Prevention of RSV in Term and Late-Preterm Infants.
Muller, W. J., Madhi, S. A., Seoane Nuñez, B., Baca Cots, M., Bosheva, M., Dagan, R., . . . MELODY Study Group. (2023). Nirsevimab for Prevention of RSV in Term and Late-Preterm Infants.. The New England journal of medicine, 388(16), 1533-1534. doi:10.1056/nejmc2214773
Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19 A Randomized Clinical Trial
Lawler, P. R., Derde, L. P. G., van de Veerdonk, F. L., McVerry, B. J., Huang, D. T., Berry, L. R., . . . Webb, S. A. (2023). Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19 A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 329(14), 1183-1196. doi:10.1001/jama.2023.4480
Implementation of a centralized pharmacovigilance system in academic pan-European clinical trials: Experience from EU-Response and conect4children consortia.
Terzić, V., Levoyer, L., Figarella, M., Bigagli, E., Mercier, N., De Gastines, L., . . . c4c safety group. (2023). Implementation of a centralized pharmacovigilance system in academic pan-European clinical trials: Experience from EU-Response and conect4children consortia.. British journal of clinical pharmacology, 89(4), 1318-1328. doi:10.1111/bcp.15669
The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
Goldswain, H., Dong, X., Penrice-Randal, R., Alruwaili, M., Shawli, G. T., Prince, T., . . . Hiscox, J. A. (2023). The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.. Genome biology, 24(1), 47. doi:10.1186/s13059-023-02881-5
Antenatal determinants of child lung development
Holden, K. A., Gibson, M., Sinha, I. P., & Hawcutt, D. B. (2023). Antenatal determinants of child lung development. doi:10.1183/2312508x.10016222
What causes poverty and how does this contribute to respiratory inequality?
Lee, A., Hawcutt, D. B., & Sinha, I. P. (2023). What causes poverty and how does this contribute to respiratory inequality?. doi:10.1183/2312508x.10003222
For children admitted to hospital, what interventions improve medication safety on ward rounds? A systematic review.
King, C., Dudley, J., Mee, A., Tomlin, S., Tse, Y., Trivedi, A., . . . Royal College of Paediatrics and Child Health/Neonatal and Paediatric Pharmacist Group Joint Standing Committee on Medicines. (2023). For children admitted to hospital, what interventions improve medication safety on ward rounds? A systematic review.. Archives of disease in childhood, archdischild-2022-324772. doi:10.1136/archdischild-2022-324772
Hypertension in Turner syndrome: a review of proposed mechanisms, management and new directions.
Jones, L., Blair, J., Hawcutt, D. B., Lip, G. Y. H., & Shantsila, A. (2023). Hypertension in Turner syndrome: a review of proposed mechanisms, management and new directions.. Journal of hypertension, 41(2), 203-211. doi:10.1097/hjh.0000000000003321
Assessing Paracetamol Overdose in Children: Acceptability and Potential Market for a Non-Invasive Testing Device.
Freitas, D., Parry, C., Seddon, G., Lemke, J., Moss, J., Freeman, N., . . . Hawcutt, D. B. (2023). Assessing Paracetamol Overdose in Children: Acceptability and Potential Market for a Non-Invasive Testing Device.. Biomedical engineering and computational biology, 14, 11795972221140108. doi:10.1177/11795972221140108
Developing and assessing health information technologies: opportunities and challenges.
Neame, M. T., Cresswell, K., Sinha, I., & Hawcutt, D. B. (2023). Developing and assessing health information technologies: opportunities and challenges.. Archives of disease in childhood. Education and practice edition, edpract-2022-324521. doi:10.1136/archdischild-2022-324521
Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.
Hurkmans, E. G. E., Klumpers, M. J., Dello Russo, C., De Witte, W., Guchelaar, H. -J., Gelderblom, H., . . . Te Loo, D. M. W. M. (2023). Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.. Frontiers in pharmacology, 13, 980309. doi:10.3389/fphar.2022.980309
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators., Higgins, A. M., Berry, L. R., Lorenzi, E., Murthy, S., McQuilten, Z., . . . Lawler, P. R. (2023). Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.. JAMA, 329(1), 39-51. doi:10.1001/jama.2022.23257
Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression
Parry, C. M., Chan, L. F., Carr, D. F., & Hawcutt, D. B. (2023). Platelet-derived growth factor D expression in adrenal cells is modulated by corticosteroids: putative role in adrenal suppression. PEDIATRIC RESEARCH, 93(1), 97-101. doi:10.1038/s41390-022-02094-9
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination
Liew, F., Talwar, S., Cross, A., Willett, B. J., Scott, S., Logan, N., . . . Openshaw, P. J. M. (2023). SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination. EBIOMEDICINE, 87. doi:10.1016/j.ebiom.2022.104402
The impact of poor housing and indoor air quality on respiratory health in children
Holden, K. A., Lee, A. R., Hawcutt, D. B., & Sinha, I. P. (2023). The impact of poor housing and indoor air quality on respiratory health in children. BREATHE, 19(2). doi:10.1183/20734735.0058-2023
2022
Factors Associated With Diabetic Ketoacidosis at Onset of Type 1 Diabetes Among Pediatric Patients: A Systematic Review.
Rugg-Gunn, C. E. M., Dixon, E., Jorgensen, A. L., Usher-Smith, J. A., Marcovecchio, M. L., Deakin, M., & Hawcutt, D. B. (2022). Factors Associated With Diabetic Ketoacidosis at Onset of Type 1 Diabetes Among Pediatric Patients A Systematic Review. JAMA PEDIATRICS, 176(12), 1248-1259. doi:10.1001/jamapediatrics.2022.3586
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review
Shamsaee, E., Huws, A., Gill, A., McWilliam, S. J., & Hawcutt, D. B. (n.d.). Ibuprofen efficacy, tolerability and safety in obese children: a systematic review. Archives of Disease in Childhood. doi:10.1136/archdischild-2022-324652
PMON268 A Multicenter, Open Label, Variable Dose, Two-Arm, Pilot Paediatric Phase 1 Pk Study To Evaluate 4.5% Testosterone Nasal Gel In Hypogonadal Boys
Lucas-Herald, A., Hawcutt, D., Thankamony, A., & Faisal Ahmed, S. (2022). PMON268 A Multicenter, Open Label, Variable Dose, Two-Arm, Pilot Paediatric Phase 1 Pk Study To Evaluate 4.5% Testosterone Nasal Gel In Hypogonadal Boys. Journal of the Endocrine Society, 6(Supplement_1), A705. doi:10.1210/jendso/bvac150.1453
Mean glucose concentrations are increased, and cardiovascular risk factors are common in children and young people with secondary adrenal insufficiency (GRACE2)
Park, J., Jones, L., Dliso, S., Hawcutt, D., Shantsila, A., Lip, G., & Blair, J. (n.d.). Mean glucose concentrations are increased, and cardiovascular risk factors are common in children and young people with secondary adrenal insufficiency (GRACE2). Endocrine Abstracts. doi:10.1530/endoabs.85.p3
Salivary adrenal biomarkers differ depending on age and sex in healthy children: preliminary data
Park, J., Jones, L., Dliso, S., Bright, O., Walker, L., Grasim, I., . . . Blair, J. (n.d.). Salivary adrenal biomarkers differ depending on age and sex in healthy children: preliminary data. Endocrine Abstracts. doi:10.1530/endoabs.85.p2
Salivary cortisol and cortisone in healthy children and young people
Dliso, S., Park, J., Jones, L., Bright, O., Shantsila, A., Hawcutt, D., . . . Blair, J. (n.d.). Salivary cortisol and cortisone in healthy children and young people. Endocrine Abstracts. doi:10.1530/endoabs.85.oc5.7
Salivary cortisol is increased in paediatric patients with turner syndrome, and the circadian rhythm is blunted: preliminary data from a pilot study
Jones, L., Blair, J., Park, J., Dliso, S., Hawcutt, D., YH, L. G., & Shantsila, A. (n.d.). Salivary cortisol is increased in paediatric patients with turner syndrome, and the circadian rhythm is blunted: preliminary data from a pilot study. Endocrine Abstracts. doi:10.1530/endoabs.85.p25
Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study
Vink, E., Davis, C., MacLean, A., Pascall, D., McDonald, S. E., Gunson, R., . . . Ho, A. (2022). Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study. OPEN FORUM INFECTIOUS DISEASES, 9(11). doi:10.1093/ofid/ofac531
Pharmacogenomic testing in paediatrics: clinical implementation strategies
Barker, C. I. S., Groeneweg, G., Maitland‐van der Zee, A. H., Rieder, M. J., Hawcutt, D. B., Hubbard, T. J., . . . Carleton, B. C. (n.d.). Pharmacogenomic testing in paediatrics: clinical implementation strategies. British Journal of Clinical Pharmacology. doi:10.1111/bcp.15181
Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19.
Siggins, M. K., Davies, K., Fellows, R., Thwaites, R. S., Baillie, J. K., Semple, M. G., . . . ISARIC4C Investigators. (2022). Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19.. Immunology. doi:10.1111/imm.13585
Paediatric glucocorticoid toxicity index: new possibilities in assessment
King, C., & Hawcutt, D. B. (2022). Paediatric glucocorticoid toxicity index: new possibilities in assessment. NATURE REVIEWS RHEUMATOLOGY. doi:10.1038/s41584-022-00848-7
Amongst chronic conditions, respiratory diseases are most inextricably linked to socioeconomic deprivation
Lee, A., Echevarria, C., Hawcutt, D., & Sinha, I. (2022). Amongst chronic conditions, respiratory diseases are most inextricably linked to socioeconomic deprivation. In EUROPEAN RESPIRATORY JOURNAL Vol. 60. doi:10.1183/13993003.congress-2022.3501
Multi-ancestral meta-analysis yields novel genetic loci for asthma exacerbations
Herrera Luis, E., Ortega, V. E., Ampleford, E. J., Sio, Y. Y., Granell, R., De Roos, E., . . . Pino-Yanes, M. (2022). Multi-ancestral meta-analysis yields novel genetic loci for asthma exacerbations. In EUROPEAN RESPIRATORY JOURNAL Vol. 60. doi:10.1183/13993003.congress-2022.685
Rapid mobilisation of parent champions empowers vulnerable families on bronchiolitis
Lee, A., Blackham, H., Khalil, H., Mlodawska, K., Parry, K., Sefton, K., . . . Sinha, I. (2022). Rapid mobilisation of parent champions empowers vulnerable families on bronchiolitis. In EUROPEAN RESPIRATORY JOURNAL Vol. 60. doi:10.1183/13993003.congress-2022.3605
Fitting to the UK COVID-19 outbreak, short-term forecasts and estimating the reproductive number
Keeling, M. J., Dyson, L., Guyver-Fletcher, G., Holmes, A., Semple, M. G., Tildesley, M. J., & Hill, E. M. (2022). Fitting to the UK COVID-19 outbreak, short-term forecasts and estimating the reproductive number. STATISTICAL METHODS IN MEDICAL RESEARCH, 31(9), 1716-1737. doi:10.1177/09622802211070257
Glucose regulation and cardiovascular health in children and young people with primary adrenal insufficiency
Park, J., Hawcutt, D., Shantsila, A., Lip, G., & Blair, J. (2022). Glucose regulation and cardiovascular health in children and young people with primary adrenal insufficiency. In HORMONE RESEARCH IN PAEDIATRICS Vol. 95 (pp. 132). Retrieved from https://www.webofscience.com/
Outcomes of the low dose short Synacthen test in infancy
Park, J., Jones, L., Dharmaraj, P., Senniappan, S., Morgan, C., Hawcutt, D., & Blair, J. (2022). Outcomes of the low dose short Synacthen test in infancy. In HORMONE RESEARCH IN PAEDIATRICS Vol. 95 (pp. 117). Retrieved from https://www.webofscience.com/
199 Challenges in identification of hypertension in children and young people with Turner Syndrome
Jones, L., Park, J., Blair, J., Hawcutt, D., Shantsila, A., & Lip, G. Y. H. (2022). 199 Challenges in identification of hypertension in children and young people with Turner Syndrome. In British Society of Paediatric Endocrinology and Diabetes (pp. A271.1-A271). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.438
430 Measuring blood pressure in children and adolescents: 20 years of change
Jones, L., Park, J., Blair, J., Hawcutt, D., Shantsila, A., & Lip, G. Y. H. (2022). 430 Measuring blood pressure in children and adolescents: 20 years of change. In British Association of General Paediatrics (pp. A108.2-A109). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.176
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis
Horby, P. W., Emberson, J. R., Mafham, M., Campbell, M., Peto, L., Pessoa-Amorim, G., . . . Landray, M. J. (2022). Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis. LANCET, 400(10349), 359-368. Retrieved from https://www.webofscience.com/
Impact of cardiometabolic multimorbidity and ethnicity on cardiovascular/renal complications in patients with COVID-19
Norris, T., Razieh, C., Zaccardi, F., Yates, T., Islam, N., Gillies, C. L., . . . Khunti, K. (2022). Impact of cardiometabolic multimorbidity and ethnicity on cardiovascular/renal complications in patients with COVID-19. HEART, 108(15), 1200-1208. doi:10.1136/heartjnl-2021-320047
Whole-genome sequencing reveals host factors underlying critical COVID-19
Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., . . . Baillie, J. K. (2022). Whole-genome sequencing reveals host factors underlying critical COVID-19. NATURE, 607(7917), 97-+. doi:10.1038/s41586-022-04576-6
Paediatric polypharmacy and deprescribing: the views of UK healthcare professionals
Moss, J. G., Young, D., Rashed, A. N., Walker, L. E., & Hawcutt, D. B. (2023). Paediatric polypharmacy and deprescribing: the views of UK healthcare professionals. ARCHIVES OF DISEASE IN CHILDHOOD, 108(1), 72-73. doi:10.1136/archdischild-2022-323827
Child poverty and health inequalities in the UK: a guide for paediatricians
Lee, A. R., Kingdon, C. C., Davie, M., Hawcutt, D., & Sinha, I. P. (2023). Child poverty and health inequalities in the UK: a guide for paediatricians. ARCHIVES OF DISEASE IN CHILDHOOD, 108(2), 94-101. doi:10.1136/archdischild-2021-323671
Multi-ancestry genome-wide association study of asthma exacerbations
Herrera-Luis, E., Ortega, V. E., Ampleford, E. J., Sio, Y. Y., Granell, R., de Roos, E., . . . Pino-Yanes, M. (2022). Multi-ancestry genome-wide association study of asthma exacerbations. PEDIATRIC ALLERGY AND IMMUNOLOGY, 33(6). doi:10.1111/pai.13802
Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission
Relph, K. A., Russell, C. D., Fairfield, C. J., Turtle, L., de Silva, T. I., Siggins, M. K., . . . Young, P. (2022). Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission. Open Forum Infectious Diseases, 9(5). doi:10.1093/ofid/ofac179
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study
Millar, J. E., Neyton, L., Seth, S., Dunning, J., Merson, L., Murthy, S., . . . Baillie, J. K. (2022). Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-08032-3
Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial
Bradbury, C. A., Lawler, P. R., Stanworth, S. J., McVerry, B. J., McQuilten, Z., Higgins, A. M., . . . Gordon, A. C. (2022). Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 327(13), 1247-1259. doi:10.1001/jama.2022.2910
Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group.
Ramanan, A. V., Modi, N., de Wildt, S. N., & c4c Learning from COVID-19 Group. (2022). Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group.. Pediatric research, 91(5), 1069-1077. doi:10.1038/s41390-021-01587-3
Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.
Hammitt, L. L., Dagan, R., Yuan, Y., Baca Cots, M., Bosheva, M., Madhi, S. A., . . . MELODY Study Group. (2022). Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.. The New England journal of medicine, 386(9), 837-846. doi:10.1056/nejmoa2110275
Eat or heat: fuel poverty and childhood respiratory health
Barrett, C., Lee, A. R., Abrams, E. M., Mayell, S. J., Hawcutt, D. B., & Sinha, I. P. (2022). Eat or heat: fuel poverty and childhood respiratory health. LANCET RESPIRATORY MEDICINE, 10(3), 229. doi:10.1016/S2213-2600(21)00584-1
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Horby, P. W., Mafham, M., Peto, L., Campbell, M., Pessoa-Amorim, G., Spata, E., . . . Landray, M. J. (2022). Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 399(10325), 665-676. Retrieved from https://www.webofscience.com/
How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper
Neumann, E., Schreeck, F., Herberg, J., Aigrain, E. J., Maitland-van der Zee, A. H., Perez-Martinez, A., . . . Schwab, M. (2022). How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. doi:10.1111/bcp.15216
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.
Dejnirattisai, W., Huo, J., Zhou, D., Zahradník, J., Supasa, P., Liu, C., . . . Screaton, G. R. (2022). SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.. Cell, 185(3), 467-484.e15. doi:10.1016/j.cell.2021.12.046
Deprescribing montelukast in children with asthma: a systematic review
Dixon, E. G., King, C., Lilley, A., Sinha, I. P., & Hawcutt, D. B. (2022). Deprescribing montelukast in children with asthma: a systematic review. BMJ OPEN, 12(1). doi:10.1136/bmjopen-2021-053112
Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study
Sullivan, M. K., Lees, J. S., Drake, T. M., Docherty, A. B., Oates, G., Hardwick, H. E., . . . Mark, P. B. (2022). Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study. NEPHROLOGY DIALYSIS TRANSPLANTATION, 37(2), 271-284. doi:10.1093/ndt/gfab303
Improving the experience of obtaining repeat complex paediatric prescriptions in the UK.
Tse, Y., Trivedi, A., Mee, A., Santosh, P., Moss, J., Batra, D., . . . Joint RCPCH/NPPG Medicines committee. (2022). Improving the experience of obtaining repeat complex paediatric prescriptions in the UK.. Archives of disease in childhood. doi:10.1136/archdischild-2020-320912
Point-of-care testing in Paediatric settings in the UK and Ireland: a cross-sectional study.
Pandey, M., Lyttle, M. D., Cathie, K., Munro, A., Waterfield, T., Roland, D., & GAPRUKI, PERUKI. (2022). Point-of-care testing in Paediatric settings in the UK and Ireland: a cross-sectional study.. BMC emergency medicine, 22(1), 6. doi:10.1186/s12873-021-00556-7
Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Horby, P. W., Pessoa-Amorim, G., Staplin, N., Emberson, J. R., Campbell, M., Spata, E., . . . Landray, M. J. (2022). Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 399(10320), 143-151. doi:10.1016/S0140-6736(21)01825-0
Identifying adolescents with Turner Syndrome at risk of poor cardiovascular outcomes: a pilot study
Jones, L., Park, J., Hawcutt, D. B., Blair, J., Lip, G. Y. H., & Shantsila, A. (2022). Identifying adolescents with Turner Syndrome at risk of poor cardiovascular outcomes: a pilot study. In JOURNAL OF HUMAN HYPERTENSION Vol. 36 (pp. 15). Retrieved from https://www.webofscience.com/
Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital
Hawcutt, D. B., Warner, N., Kenyon, E., Murray, C., Taylor, J., Moss, J., . . . Murdock, N. (2022). Implementing a specialist paediatric clinical pharmacology service in a UK children's hospital. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(1), 206-213. doi:10.1111/bcp.14944
Information for children and young people about reporting suspected adverse drug reactions
Hawcutt, D. B., Jadeja, M., Bhoombla, N., Smith, S., & McWilliam, S. J. (2022). Information for children and young people about reporting suspected adverse drug reactions. ARCHIVES OF DISEASE IN CHILDHOOD, 107(7), 681-685. doi:10.1136/archdischild-2021-323400
Pharmacogenomics and asthma treatment: acceptability to children, families and healthcare professionals.
Parry, C. M., Seddon, G., Rogers, N., Sinha, I. P., Bracken, L., King, C., . . . Hawcutt, D. B. (2022). Pharmacogenomics and asthma treatment: acceptability to children, families and healthcare professionals. ARCHIVES OF DISEASE IN CHILDHOOD, 107(4), 394-399. doi:10.1136/archdischild-2021-322396
Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol
Knight, S. R., Gupta, R. K., Ho, A., Pius, R., Buchan, I., Carson, G., . . . Harrison, E. M. (2022). Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. THORAX, 77(6), 606-615. doi:10.1136/thoraxjnl-2021-217629
2021
Mapping the human genetic architecture of COVID-19
Niemi, M. E. K., Karjalainen, J., Daly, M., Ganna, A., Mehtonen, J., Cordioli, M., . . . Dopazo, X. (2021). Mapping the human genetic architecture of COVID-19. NATURE, 600(7889), 472-+. doi:10.1038/s41586-021-03767-x
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity
Fallerini, C., Picchiotti, N., Baldassarri, M., Zguro, K., Daga, S., Fava, F., . . . Furini, S. (2021). Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity.. Human genetics, 141(1), 147-173. doi:10.1007/s00439-021-02397-7
Beclometasone but not fluticasone modulates PDGFD expression in the H295R adrenal cell line.
Deprescribing montelukast in children with asthma: A systematic review
Dixon, E., King, C., Lilley, A., Sinha, I., & Hawcutt, D. (2021). Deprescribing montelukast in children with asthma: A systematic review. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 4891). Retrieved from https://www.webofscience.com/
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells
de, S. T. I., Liu, G., Lindsey, B. B., Dong, D., Moore, S. C., Hsu, N. S., . . . Dong, T. (2021). The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. ISCIENCE, 24(11). doi:10.1016/j.isci.2021.103353
Glucose regulation and cardiovascular health in children and young people (CYP) with primary adrenal insufficiency: preliminary data (GRACE study)
Park, J., Hawcutt, D., Shantsila, A., Lip, G., & Blair, J. (n.d.). Glucose regulation and cardiovascular health in children and young people (CYP) with primary adrenal insufficiency: preliminary data (GRACE study). Endocrine Abstracts. doi:10.1530/endoabs.78.p2
Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia
Bielicki, J. A., Stohr, W., Barratt, S., Dunn, D., Naufal, N., Roland, D., . . . Sharland, M. (2021). Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia The CAP-IT Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(17), 1713-1724. doi:10.1001/jama.2021.17843
A prenylated dsRNA sensor protects against severe COVID-19
Wickenhagen, A., Sugrue, E., Lytras, S., Kuchi, S., Noerenberg, M., Turnbull, M. L., . . . Wilson, S. J. (2021). A prenylated dsRNA sensor protects against severe COVID-19. SCIENCE, 374(6567). doi:10.1126/science.abj3624
Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study
Hurst, E. A., Mellanby, R. J., Handel, I., Griffith, D. M., Rossi, A. G., Walsh, T. S., . . . Russell, C. D. (2021). Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study. BMJ OPEN, 11(10). doi:10.1136/bmjopen-2021-055435
Adverse drug reactions of leukotriene receptor antagonists in children with asthma: a systematic review
Dixon, E., Rugg-Gunn, C., Sellick, V., Sinha, I., & Hawcutt, D. (2021). Adverse drug reactions of leukotriene receptor antagonists in children with asthma: A systematic review. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(12), 4890-4891. Retrieved from https://www.webofscience.com/
Adverse drug reactions of leukotriene receptor antagonists in children with asthma: a systematic review
Dixon, E., Rugg-Gunn, C., Sinha, I., & Hawcutt, D. (2021). Adverse drug reactions of leukotriene receptor antagonists in children with asthma: a systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 58. doi:10.1183/13993003.congress-2021.PA3919
Deprescribing montelukast in children with asthma: a systematic review
Dixon, E., King, C., Hawcutt, D., & Sinha, I. (2021). Deprescribing montelukast in children with asthma: a systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 58. doi:10.1183/13993003.congress-2021.PA3928
Severity Scores used in the assessment of Bronchiolitis: A systematic review
Bedson, W., Wilkinson, E., Hawcutt, D., & Mcnamara, P. (2021). Severity Scores used in the assessment of Bronchiolitis: A systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 58. doi:10.1183/13993003.congress-2021.OA2846
Severity scores published for acute wheeze in preschool children: a systematic review
Wilkinson, E., Bedson, W., Mcnamara, P., & Hawcutt, D. (2021). Severity scores published for acute wheeze in preschool children: a systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 58. doi:10.1183/13993003.congress-2021.PA2163
Assessment of blood pressure and carotid intima media thickness (CIMT) in children with primary adrenal insufficiency
Park, J., Shantsila, H., Hawcutt, D., Lip, G., & Blair, J. (2021). Assessment of blood pressure and carotid intima media thickness (CIMT) in children with primary adrenal insufficiency. In HORMONE RESEARCH IN PAEDIATRICS Vol. 94 (pp. 197). Retrieved from https://www.webofscience.com/
COVID-19 and the mental health of children with respiratory illness.
Sinha, I. P., Murphy, R., Biffin, H., Gait, L., Abrams, E. M., Lee, A. R., . . . Brown, A. (2021). COVID-19 and the mental health of children with respiratory illness. LANCET RESPIRATORY MEDICINE, 9(9), 952-954. doi:10.1016/S2213-2600(21)00319-2
Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol
Sigfrid, L., Drake, T. M., Pauley, E., Jesudason, E. C., Olliaro, P., Lim, W. S., . . . Scott, J. T. (2021). Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. LANCET REGIONAL HEALTH-EUROPE, 8. doi:10.1016/j.lanepe.2021.100186
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19
Goligher, E. C., Bradbury, C. A., McVerry, B. J., Lawler, P. R., Berger, J. S., Gong, M. N., . . . Zhong, Y. (2021). Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. NEW ENGLAND JOURNAL OF MEDICINE, 385(9), 777-789. doi:10.1056/NEJMoa2103417
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19
Lawler, P. R., Golighe, E. C., Berge, J. S., Neal, M. D., McVerry, B. J., Nicolau, J. C., . . . Zampieri, F. G. (2021). Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. NEW ENGLAND JOURNAL OF MEDICINE, 385(9), 790-802. doi:10.1056/NEJMoa2105911
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study
Russell, C. D., Fairfield, C. J., Drake, T. M., Turtle, L., Seaton, R. A., Wootton, D. G., . . . Ho, A. (2021). Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study. LANCET MICROBE, 2(8), E354-E365. doi:10.1016/S2666-5247(21)00090-2
Genome-wide association studies of exacerbations in children using long-acting beta2-agonists
Slob, E. M. A., Richards, L. B., Vijverberg, S. J. H., Longo, C., Koppelman, G. H., Pijnenburg, M. W. H., . . . Maitland-van der Zee, A. H. (2021). Genome-wide association studies of exacerbations in children using long-acting beta2-agonists. PEDIATRIC ALLERGY AND IMMUNOLOGY, 32(6), 1197-1207. doi:10.1111/pai.13494
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial
Arabi, Y. M., Gordon, A. C., Derde, L. P. G., Nichol, A. D., Murthy, S., Al Beidh, F., . . . Webb, S. A. (2021). Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial. INTENSIVE CARE MEDICINE, 47(8), 867-886. doi:10.1007/s00134-021-06448-5
Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma
Hernandez-Pacheco, N., Gorenjak, M., Li, J., Repnik, K., Vijverberg, S. J., Berce, V., . . . Pino-Yanes, M. (n.d.). Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma. Journal of Personalized Medicine, 11(8), 733. doi:10.3390/jpm11080733
ADRB2 Haplotypes and Asthma Exacerbations in Children and Young Adults: An Individual Participant Data Meta-Analysis.
Karimi, L., Vijverberg, S. J., Engelkes, M., Hernandez-Pacheco, N., Farzan, N., Soares, P., . . . PiCA, SysPharmPedia consortia. (2021). ADRB2 Haplotypes and Asthma Exacerbations in Children and Young Adults: An Individual Participant Data Meta-Analysis.. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. doi:10.1111/cea.13965
Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study
Drake, T. M., Riad, A. M., Fairfield, C. J., Egan, C., Knight, S. R., Pius, R., . . . Semple, M. G. (2021). Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. LANCET, 398(10296), 223-237. Retrieved from https://www.webofscience.com/
Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK
Docherty, A., Mulholland, R., Lone, N. I., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . Semple, M. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 773-785. doi:10.1016/S2213-2600(21)00175-2
Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study
Drake, T. M., Fairfield, C. J., Pius, R., Knight, S. R., Norman, L., Girvan, M., . . . ISARIC4C Investigators. (2021). Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study.. The Lancet. Rheumatology, 3(7), e498-e506. doi:10.1016/s2665-9913(21)00104-1
Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: t: a matched, prospective cohort study
Hawcutt, D. (2021). Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: t: a matched, prospective cohort study. The Lancet Rheumatology.
Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID-19: Analysis of the ISARIC CCP-UK Cohort
Yates, T., Zaccardi, F., Islam, N., Razieh, C., Gillies, C. L., Lawson, C. A., . . . Khunti, K. (2021). Obesity, Ethnicity, and Risk of Critical Care, Mechanical Ventilation, and Mortality in Patients Admitted to Hospital with COVID-19: Analysis of the ISARIC CCP-UK Cohort. OBESITY, 29(7), 1223-1230. doi:10.1002/oby.23178
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK
Bloom, C. I., Drake, T. M., Docherty, A. B., Lipworth, B. J., Johnston, S. L., Nguyen-Van-Tam, J. S., . . . Openshaw, P. J. M. (2021). Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 699-711. doi:10.1016/S2213-2600(21)00013-8
Stepping down asthma treatment in children
King, C., Dixon, E., & Hawcutt, D. B. (2021). Stepping down asthma treatment in children. PEDIATRIC PULMONOLOGY, 56(7), 1823-1824. doi:10.1002/ppul.25410
Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England
Leclerc, Q. J., Fuller, N. M., Keogh, R. H., Diaz-Ordaz, K., Sekula, R., Semple, M. G., . . . Knight, G. M. (2021). Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England. BMC HEALTH SERVICES RESEARCH, 21(1). doi:10.1186/s12913-021-06509-x
Update and harmonisation of guidance for the management of diabetic ketoacidosis in children and young people in the UK
Rugg-Gunn, C. E. M., Deakin, M., & Hawcutt, D. B. (2021). Update and harmonisation of guidance for the management of diabetic ketoacidosis in children and young people in the UK. BMJ PAEDIATRICS OPEN, 5(1). doi:10.1136/bmjpo-2021-001079
Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial
Horby, P. W., Landray, M. J., & Grp, R. E. C. O. V. E. R. Y. C. (2021). Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. LANCET, 397(10289), 2049-2059. doi:10.1016/S0140-6736(21)00897-7
Adverse drug reactions in children and young people
Adverse drug reactions in children and young people (2021). Pharmaceutical Journal. doi:10.1211/pj.2021.1.75935
Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use
Hernandez-Pacheco, N., Vijverberg, S. J., Herrera-Luis, E., Li, J., Sio, Y. Y., Granell, R., . . . Maitland-van der Zee, A. H. (2021). Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use. EUROPEAN RESPIRATORY JOURNAL, 57(5). doi:10.1183/13993003.03388-2020
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Horby, P. W., & Landray, M. J. (2021). Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 397(10285), 1637-1645. Retrieved from https://www.webofscience.com/
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
Gordon, A. C., Al-Beidh, F., Rowan, K. M., Nichol, A. D., Arabi, Y. M., Annane, D., . . . Derde, L. P. G. (2021). Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19. NEW ENGLAND JOURNAL OF MEDICINE, 384(16), 1491-1502. doi:10.1056/NEJMoa2100433
Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma
Hernandez-Pacheco, N., Gorenjak, M., Jurgec, S., Corrales, A., Jorgensen, A., Karimi, L., . . . Pino-Yanes, M. (2021). Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma. ALLERGY, 76(4), 1238-1243. doi:10.1111/all.14552
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
Gupta, R. K., Harrison, E. M., Ho, A., Docherty, A. B., Knight, S. R., van Smeden, M., . . . Noursadeghi, M. (2021). Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study. LANCET RESPIRATORY MEDICINE, 9(4), 349-359. doi:10.1016/S2213-2600(20)30559-2
Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol
Sigfrid, L., Drake, T., Pauley, E., Jesudason, E., Olliaro, P., Lim, W. S., . . . ISARIC4C investigators. (2021). Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. doi:10.1101/2021.03.18.21253888
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19.
Thwaites, R. S., Sanchez Sevilla Uruchurtu, A., Siggins, M. K., Liew, F., Russell, C. D., Moore, S. C., . . . ISARIC4C investigators. (2021). Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19.. Science Immunology, 6(57). doi:10.1126/sciimmunol.abg9873
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
Thomson, E. C., Rosen, L. E., Shepherd, J. G., Spreafico, R., Filipe, A. D. S., Wojcechowskyj, J. A., . . . Snell, G. (2021). Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity. CELL, 184(5), 1171-+. doi:10.1016/j.cell.2021.01.037
Genetic mechanisms of critical illness in COVID-19
Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A. D., Rawlik, K., Pasko, D., . . . Baillie, J. K. (2021). Genetic mechanisms of critical illness in COVID-19. NATURE, 591(7848), 92-+. doi:10.1038/s41586-020-03065-y
Erratum to “COVID-19 in children: what did we learn from the first waveˮ [Paediatr Child Health 30 (2020) 438–443/1496]
Bogiatzopoulou, A., Mayberry, H., Hawcutt, D. B., Whittaker, E., Munro, A., Roland, D., . . . Harwood, R. (2021). Erratum to "COVID-19 in children: what did we learn from the first waveˮ [Paediatr Child Health 30 (2020) 438-443/1496].. Paediatrics and child health, 31(3), 128. doi:10.1016/j.paed.2021.01.001
Prospective identification and causality evaluation of suspected adverse drug reactions in neonates
Roberts, E. K., Hawcutt, D. B., & Turner, M. A. (2021). Prospective identification and causality evaluation of suspected adverse drug reactions in neonates. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(3), 1541-1546. doi:10.1111/bcp.14485
The safety of hydroxychloroquine in paediatric populations: Analysis of worldwide pharmacovigilance reports
Hawcutt, D., McWilliam, S., Rodriguez-Martinez, C., Pacheco, R., Hedrich, C., Sinha, I., & Fernandes, R. (2021). The safety of hydroxychloroquine in paediatric populations: Analysis of worldwide pharmacovigilance reports. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 1622-1623). Retrieved from https://www.webofscience.com/
Thiopurine methyltransferase activity and adverse effects of azathioprine in at risk paediatric inflammatory bowel disease patients
Parry, C., Hawcutt, D., Krishnamurthy, S., & Renji, E. (2021). Thiopurine methyltransferase activity and adverse effects of azathioprine in at risk paediatric inflammatory bowel disease patients. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 1622). Retrieved from https://www.webofscience.com/
Dexamethasone in Hospitalized Patients with Covid-19
Wootton, D., & The RECOVERY Collaborative Group. (2021). Dexamethasone in Hospitalized Patients with Covid-19. New England Journal of Medicine, 384(8), 693-704. doi:10.1056/nejmoa2021436
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Horby, P. W., Roddick, A., Spata, E., Staplin, N., Emberson, J., Pessoa-Amorim, G., . . . Yates, H. (2021). Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. LANCET, 397(10274), 605-612. doi:10.1016/S0140-6736(21)00149-5
Importance of patient bed pathways and length of stay differences in predicting COVID-19 bed occupancy in England
Leclerc, Q., Fuller, N., Keogh, R., Diaz-Ordaz, K., Sekula, R., Semple, M., . . . Knight, G. (2021). Importance of patient bed pathways and length of stay differences in predicting COVID-19 bed occupancy in England. doi:10.1101/2021.01.14.21249791
Glucose regulation in children with primary adrenal insufficiency: preliminary data
Park, J., Hawcutt, D., Shantsila, H., Lip, G., & Blair, J. (2021). Glucose regulation in children with primary adrenal insufficiency: preliminary data. In HORMONE RESEARCH IN PAEDIATRICS Vol. 94 (pp. 70-71). Retrieved from https://www.webofscience.com/
2020
Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19
Horby, P., Mafham, M., Linsell, L., Bell, J. L., Staplin, N., Emberson, J. R., . . . Landray, M. J. (2020). Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19. NEW ENGLAND JOURNAL OF MEDICINE, 383(21), 2030-2040. doi:10.1056/NEJMoa2022926
The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity
Thomson, E., Rosen, L., Shepherd, J., Spreafico, R., da Silva Filipe, A., Wojcechowskyj, J., . . . Snell, G. (2020). The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity. doi:10.1101/2020.11.04.355842
Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020
Thompson, C. P., Grayson, N. E., Paton, R. S., Bolton, J. S., Lourenco, J., Penman, B. S., . . . Simmonds, P. (2020). Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020. EUROSURVEILLANCE, 25(42), 33-41. doi:10.2807/1560-7917.ES.2020.25.42.2000685
Pediatric Asthma and COVID-19: the Known, the Unknown and the Controversial.
Abrams, E. M., Sinha, I., Fernandes, R. M., & Hawcutt, D. B. (2020). Pediatric Asthma and COVID-19: the Known, the Unknown and the Controversial.. Pediatric pulmonology. doi:10.1002/ppul.25117
Elevated antiviral, myeloid and endothelial inflammatory markers in severe COVID-19
Thwaites, R., Sevilla Uruchurtu, A. S., Siggins, M., Liew, F., Russell, C., Moore, S., . . . Openshaw, P. J. M. (2020). Elevated antiviral, myeloid and endothelial inflammatory markers in severe COVID-19. doi:10.1101/2020.10.08.20209411
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Angus, D. C., Derde, L., Al-Beidh, F., Annane, D., Arabi, Y., Beane, A., . . . Summers, C. (2020). Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.. JAMA, 324(13), 1317-1329. doi:10.1001/jama.2020.17022
Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study.
Drake, T. M., Docherty, A. B., Harrison, E. M., Quint, J. K., Adamali, H., Agnew, S., . . . ISARIC4C Investigators. (2020). Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study.. Am J Respir Crit Care Med. doi:10.1164/rccm.202007-2794OC
Pediatric acute asthma scoring systems: a systematic review and survey of UK practice
Chacko, J., King, C., Harkness, D., Messahel, S., Grice, J., Roe, J., . . . Hawcutt, D. B. (2020). Pediatric acute asthma scoring systems: a systematic review and survey of UK practice. JOURNAL OF THE AMERICAN COLLEGE OF EMERGENCY PHYSICIANS OPEN, 1(5), 1000-1008. doi:10.1002/emp2.12083
Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation
King, C., McKenna, A., Farzan, N., Vijverberg, S. J., van der Schee, M. P., Maitland-van der Zee, A. H., . . . Hawcutt, D. B. (2020). Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation. In PHARMACOGENOMICS JOURNAL Vol. 20 (pp. 621-628). doi:10.1038/s41397-019-0140-y
COVID-19 in children: what did we learn from the first wave?
Bogiatzopoulou, A., Mayberry, H., Hawcutt, D. B., Whittaker, E., Munro, A., Roland, D., . . . Harwood, R. (2020). COVID-19 in children: what did we learn from the first wave?. Paediatrics and child health. doi:10.1016/j.paed.2020.09.005
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.
Knight, S. R., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T. M., . . . ISARIC4C investigators. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.. BMJ: British Medical Journal, 370. doi:10.1136/bmj.m3339
A systematic review of the impact of food insecurity on the risk of developing asthma, or having poor asthma control, in childhood
Mahmood, S., Cheetham, S., Brown, L., Hawcutt, D., Lawrence, P., Mayell, S., . . . Sinha, I. (2020). A systematic review of the impact of food insecurity on the risk of developing asthma, or having poor asthma control, in childhood. In EUROPEAN RESPIRATORY JOURNAL Vol. 56. doi:10.1183/13993003.congress-2020.3510
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study
Swann, O., Holden, K., Turtle, L., Pollock, L., Fairfield, C., Drake, T., . . . ISARIC Coronavirus Clinical Characterisation Consortium (ISARIC4C) Investigators. (2020). Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study. BMJ, 370. doi:10.1136/bmj.m3249
Robust, reproducible clinical patterns in hospitalised patients with COVID-19
Millar, J., Neyton, L., Seth, S., Dunning, J., Merson, L., Murthy, S., . . . Baillie, K. (2020). Robust, reproducible clinical patterns in hospitalised patients with COVID-19. doi:10.1101/2020.08.14.20168088
Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol (UK): a prospective observational study
Geretti, A., Stockdale, A., Kelly, S., Villa, G., Turtle, L., Semple, M., & Sabin, C. (2020). Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol (UK): a prospective observational study. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 23, 13-14. Retrieved from https://www.webofscience.com/
Salivary cortisol, cortisone and serum cortisol concentrations are related to age and body mass index in healthy children and young people.
Titman, A., Price, V., Hawcutt, D., Chesters, C., Ali, M., Cacace, G., . . . Blair, J. C. (2020). Salivary cortisol, cortisone and serum cortisol concentrations are related to age and body mass index in healthy children and young people.. Clinical endocrinology. doi:10.1111/cen.14294
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
Knight, S., Ho, A., Pius, R., Buchan, I., Carson, G., Drake, T., . . . Harrison, E. (2020). Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score. doi:10.1101/2020.07.30.20165464
Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic
Sinha, I. P., Lee, A. R., Bennett, D., McGeehan, L., Abrams, E. M., Mayell, S. J., . . . Taylor-Robinson, D. C. (2020). Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic. The Lancet Respiratory Medicine, 8(8), 762-763. doi:10.1016/s2213-2600(20)30280-0
Correction: Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritization
King, C., McKenna, A., Farzan, N., Vijverberg, S. J., van der Schee, M. P., Maitland-van der Zee, A. H., . . . Hawcutt, D. B. (2020). Correction: Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritization. Pharmacogenomics J. doi:10.1038/s41397-020-0178-x
Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study
Swann, O., Holden, K., Turtle, L., Pollock, L., Fairfield, C., Drake, T., . . . Semple, M. (2020). Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study. doi:10.1101/2020.07.14.20153320
Pharmacovigilance Reports Received from Children and Young People, and Development of Information to Aid Future Reporting from this Age Group
Bhoombla, N., Preston, J., Ainsworth, J., Bird, H., Jadeja, M., King, C., & Hawcutt, D. B. (2020). Pharmacovigilance Reports Received from Children and Young People, and Development of Information to Aid Future Reporting from this Age Group. PEDIATRIC DRUGS, 22(3), 335-341. doi:10.1007/s40272-020-00391-6
Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic
Sinha, I. P., Lee, A. R., Bennett, D., McGeehan, L., Abrams, E. M., Mayell, S. J., . . . Taylor-Robinson, D. C. (2020). Child poverty, food insecurity, and respiratory health during the COVID-19 pandemic. LANCET RESPIRATORY MEDICINE, 8(8), 762-763. Retrieved from https://www.webofscience.com/
Efficacy, safety and cost-effectiveness of hydroxychloroquine in children with COVID-19: a call for evidence.
Rodríguez-Martínez, C. E., Fernandes, R. M., Hawcutt, D. B., Sinha, I., & Pacheco, R. L. (2020). Efficacy, safety and cost-effectiveness of hydroxychloroquine in children with COVID-19: a call for evidence.. Acta paediatrica (Oslo, Norway : 1992). doi:10.1111/apa.15373
COVID-19 infection in children
Sinha, I. P., Harwood, R., Semple, M. G., Hawcutt, D. B., Thursfield, R., Narayan, O., . . . Southern, K. W. (2020). COVID-19 infection in children. LANCET RESPIRATORY MEDICINE, 8(5), 446-447. Retrieved from https://www.webofscience.com/
Fifteen-minute consultation: Pharmacogenomics: a guide for busy clinicians
Parry, C. M., & Hawcutt, D. (2020). Fifteen-minute consultation: Pharmacogenomics: a guide for busy clinicians. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 105(2), 107-110. doi:10.1136/archdischild-2019-316971
Ranitidine in short supply: why now, and where next?
Ryan, M. E., Barker, C., & Hawcutt, D. B. (2020). Ranitidine in short supply: why now, and where next?. ARCHIVES OF DISEASE IN CHILDHOOD, 105(4), 382-383. doi:10.1136/archdischild-2019-318447
The impact of paediatric dose range checking software
Neame, M., Moss, J., Saez Dominguez, J., Gill, A., Barnes, N., Sinha, I., & Hawcutt, D. (2020). The impact of paediatric dose range checking software. European Journal of Hospital Pharmacy. doi:10.1136/ejhpharm-2020-002244
Patient-focused outcomes are infrequently reported in pediatric health information technology trials: a systematic review
Neame, M. T., Chacko, J., Kirkham, J. J., Sinha, I. P., & Hawcutt, D. B. (2020). Patient-focused outcomes are infrequently reported in pediatric health information technology trials: a systematic review. JOURNAL OF CLINICAL EPIDEMIOLOGY, 119, 117-125. doi:10.1016/j.jclinepi.2019.11.017
Where next for inhaled corticosteroids in childhood asthma?
Sinha, I. P., Dodd, S. R., Grime, C., Hawcutt, D. B., Fernandes, R. M., Roberts, M. R., . . . Williamson, P. R. (2020). Where next for inhaled corticosteroids in childhood asthma?. LANCET RESPIRATORY MEDICINE, 8(4), 345. doi:10.1016/S2213-2600(20)30013-8
2019
Adverse events and cardiovasular effects of vilanterol in paediatric asthma: a systematic review
Austin, R., Sinha, I., & Hawcutt, D. (2019). Adverse events and cardiovasular effects of vilanterol in paediatric asthma: a systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA960
Dexamethasone or prednisolone for acute asthma exacerbations in children: a meta-analysis
Nitchingham, D., Hawcutt, D., Fernandes, R., Kapitein, B., Andrew, L., Grice, J., . . . Sinha, I. (2019). Dexamethasone or prednisolone for acute asthma exacerbations in children: a meta-analysis. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA952
Meta-analysis of inhaled corticosteroids response in children with asthma
Hernandez-Pacheco, N., Vijverberg, S. J., Gorenjak, M., Flores, C., Francis, B., Farzan, N., . . . Pino-Yanes, M. (2019). Meta-analysis of inhaled corticosteroids response in children with asthma. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA5434
Oral steroids for preschool children with acute wheeze: a systematic review and meta-analysis
Murphy, J., King, C., Kapitein, B., Fernandes, R., Lilley, A., Messahel, S., . . . Sinha, I. (2019). Oral steroids for preschool children with acute wheeze: a systematic review and meta-analysis. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.OA4941
The effects of ambient air pollution on the risk of hospitalisation with acute respiratory illnesses in children: an overview of systematic reviews
King, C., Surace, A. E., Jeffers, G., Hawcutt, D., & Sinha, I. (2019). The effects of ambient air pollution on the risk of hospitalisation with acute respiratory illnesses in children: an overview of systematic reviews. In EUROPEAN RESPIRATORY JOURNAL Vol. 54. doi:10.1183/13993003.congress-2019.PA2834
Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study
DB, H., B, F., DF, C., AL, J., P, Y., N, W., . . . M, P. (n.d.). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. Yearbook of Paediatric Endocrinology. doi:10.1530/ey.16.8.11
Assessing the impact of breathing retraining on asthma symptoms and dysfunctional breathing in children
Hepworth, C., Sinha, I., Saint, G. L., & Hawcutt, D. B. (2019). Assessing the impact of breathing retraining on asthma symptoms and dysfunctional breathing in children. PEDIATRIC PULMONOLOGY, 54(6), 706-712. doi:10.1002/ppul.24300
Genome-wide association study of inhaled corticosteroid response in admixed children with asthma
Hawcutt, D. B., & Pirmohamed, M. (2019). Genome-wide association study of inhaled corticosteroid response in admixed children with asthma. Clinical and Experimental Allergy, 49(6), 789-798. doi:10.1111/cea.13354
P44 Type 2 diabetes mellitus in children: non-insulin medication, where are we up to?
Austin, R., Paul, P., & Hawcutt, D. (2019). P44 Type 2 diabetes mellitus in children: non-insulin medication, where are we up to?. Archives of Disease in Childhood, 104(6), e35.2-e35. doi:10.1136/archdischild-2019-esdppp.82
P45 The acceptability of using genetic information to guide treatment of asthma to children, young people, and parents (pilot study)
King, C., Bracken, L., McDonough, E., Pirmohamed, M., Peak, M., & Hawcutt, D. (2019). P45 The acceptability of using genetic information to guide treatment of asthma to children, young people, and parents (pilot study). Archives of Disease in Childhood, 104(6), e35.3-e36. doi:10.1136/archdischild-2019-esdppp.83
P46 Spontaneous reporting of suspected adverse drug reactions by children and young people: past, present and future
King, C., Bhoombla, N., Clarke, J., Morgan, V., Preston, J., Ainsworth, J., . . . Hawcutt, D. (2019). P46 Spontaneous reporting of suspected adverse drug reactions by children and young people: past, present and future. Archives of Disease in Childhood, 104(6), e36.1-e36. doi:10.1136/archdischild-2019-esdppp.84
P69 Pharmacokinetics of a continuous infusion of piperacillin/tazobactam to children using an elastomeric pump (POPPET Study): pilot data from double lumen central lines
Moss, J., Price, V., Paulus, S., Ramos-Martin, V., Melaine, A., Evans, E., . . . Pizer, B. (2019). P69 Pharmacokinetics of a continuous infusion of piperacillin/tazobactam to children using an elastomeric pump (POPPET Study): pilot data from double lumen central lines. Archives of Disease in Childhood, 104(6), e45.3-e46. doi:10.1136/archdischild-2019-esdppp.107
P70 Identifying and managing problematic polypharmacy in children and young people?
Moss, J., Austin, R., & Hawcutt, D. (2019). P70 Identifying and managing problematic polypharmacy in children and young people?. Archives of Disease in Childhood, 104(6), e46.1-e46. doi:10.1136/archdischild-2019-esdppp.108
G76(P) Paediatric patient portals: variations in perception of benefit and risk amongst key stakeholders
Neame, M., Thompson, H., Sinha, I. P., Hawcutt, D., & Barnes, N. (2019). G76(P) Paediatric patient portals: variations in perception of benefit and risk amongst key stakeholders. In QUALITY IMPROVEMENT; EMBEDDING A CULTURE OF QUALITY IMPROVEMENT (pp. A31.3-A32). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2019-rcpch.75
A systematic review of the effects of implementing clinical pathways supported by health information technologies
Neame, M. T., Chacko, J., Surace, A. E., Sinha, I. P., & Hawcutt, D. B. (2019). A systematic review of the effects of implementing clinical pathways supported by health information technologies. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 26(4), 356-363. doi:10.1093/jamia/ocy176
Working together to deliver stratified medicine research effectively
Attar, S. G., Poustie, V. J., Hawcutt, D. B., Oni, L., Beresford, M. W., & Pirmohamed, M. (2019). Working together to deliver stratified medicine research effectively. British Medical Bulletin. doi:10.1093/bmb/ldz003
Seizures and quinolone antibiotics in children: a systematic review of adverse events
Neame, M., King, C., Iyer, A. S., Kneen, R., Sinha, I., & Hawcutt, D. B. (2019). Seizures and quinolone antibiotics in children: a systematic review of adverse events. European Journal of Hospital Pharmacy. doi:10.1136/ejhpharm-2018-001805
Contribution of respiratory viruses and bacteria to community-acquired pneumonia in highly vaccinated children: a case-control study.
Saint, G. L., Hawcutt, D. B., & McNamara, P. S. (2019). Contribution of respiratory viruses and bacteria to community-acquired pneumonia in highly vaccinated children: a case-control study.. Thorax. doi:10.1136/thoraxjnl-2018-212625
2018
Quantitation of salbutamol using micro-volume blood sampling - applications to exacerbations of pediatric asthma
Cordell, R. L., Valkenburg, T. S. E., Pandya, H. C., Hawcutt, D. B., Semple, M. G., & Monks, P. S. (2018). Quantitation of salbutamol using micro-volume blood sampling - applications to exacerbations of pediatric asthma. JOURNAL OF ASTHMA, 55(11), 1205-1213. doi:10.1080/02770903.2017.1402341
17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use.
Farzan, N., Vijverberg, S. J., Hernandez-Pacheco, N., Bel, E. H. D., Berce, V., Bonnelykke, K., . . . Maitland-van der Zee, A. -H. (2018). 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. ALLERGY, 73(10), 2083-2088. doi:10.1111/all.13499
Identification of a novel locus associated with asthma treatment response with inhaled corticosteroids in African-admixed children
Hernandez-Pacheco, N., Farzan, N., Vijverberg, S., Francis, B., Schieck, M., Pirmohamed, M., . . . Pino-Yanes, M. (2018). Identification of a novel locus associated with asthma treatment response with inhaled corticosteroids in African-admixed children. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 26 (pp. 693-694). Retrieved from https://www.webofscience.com/
The effect of ambient air pollution on the risk of hospitalisation with bronchiolitis in infants: A systematic review.
King, C., Hawcutt, D., Kirkham, J., & Sinha, I. (2018). The effect of ambient air pollution on the risk of hospitalisation with bronchiolitis in infants: A systematic review.. In EUROPEAN RESPIRATORY JOURNAL Vol. 52. doi:10.1183/13993003.congress-2018.PA4648
Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study
DB, H., B, F., DF, C., AL, J., P, Y., N, W., . . . M, P. (n.d.). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. Yearbook of Paediatric Endocrinology. doi:10.1530/ey.15.8.6
Identifying cisplatin-induced kidney damage in paediatric oncology patients
Barton, C. D., Pizer, B., Jones, C., Oni, L., Pirmohamed, M., & Hawcutt, D. B. (2018). Identifying cisplatin-induced kidney damage in paediatric oncology patients. PEDIATRIC NEPHROLOGY, 33(9), 1467-1474. doi:10.1007/s00467-017-3765-6
Adrenal suppression with inhaled corticosteroids: the seed and the soil – Authors' reply
Hawcutt, D. B., Francis, B., & Pirmohamed, M. (2018). Adrenal suppression with inhaled corticosteroids: the seed and the soil reply. LANCET RESPIRATORY MEDICINE, 6(6), E20. doi:10.1016/S2213-2600(18)30149-8
Optimising the dosing of intravenous theophylline in acute severe asthma in children
Saint, G. L., Semple, M., Sinha, I., & Hawcutt, D. B. (2018). Optimising the dosing of intravenous theophylline in acute severe asthma in children. Pediatric Drugs, 20(3), 209-214. doi:10.1007/s40272-017-0281-x
Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study
Hawcutt, D. B., Francis, B., Carr, D., Jorgensen, A. L., Yin, P., Wallin, N., . . . Pirmohamed, M. (2018). Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study. The Lancet Respiratory Medicine, 6(6), 442-450. doi:10.1016/S2213-2600(18)30058-4
Solving the problem of dose optimisation of children’s medicines
McWilliam, S., & Hawcutt, D. B. (2018). Solving the problem of dose optimisation of children’s medicines. Expert Review of Clinical Pharmacology, 11(3), 205-208. doi:10.1080/17512433.2018.1431528
The effect of outdoor air pollution on the risk of hospitalisation for bronchiolitis in infants: a systematic review
King, C., Kirkham, J., Hawcutt, D., & Sinha, I. (2018). The effect of outdoor air pollution on the risk of hospitalisation for bronchiolitis in infants: a systematic review. PEERJ, 6. doi:10.7717/peerj.5352
2017
O-24 Adrin 1 methodology study: adverse drug reactions in neonates: what are the best ways to evaluate suspected adverse drug reactions in neonates?
Roberts., Hawcutt., & Turner. (2017). O-24 Adrin 1 methodology study: adverse drug reactions in neonates: what are the best ways to evaluate suspected adverse drug reactions in neonates?. In Archives of Disease in Childhood Vol. 102 (pp. A11.2-A11). BMJ. doi:10.1136/archdischild-2017-esdppp.24
O-41 Pharmacogenomic studies of corticosteroid effectiveness in paediatric asthma: a systematic review
Hawcutt., & Thomas. (2017). O-41 Pharmacogenomic studies of corticosteroid effectiveness in paediatric asthma: a systematic review. In Archives of Disease in Childhood Vol. 102 (pp. A19.1-A19). BMJ. doi:10.1136/archdischild-2017-esdppp.41
Overview of Systematic Reviews of Therapeutic Ranges: Establishing the Threshold of Increased Drug Toxicity
Moss, J., Cooney, L., Golder, S., Loke, Y., Jorgensen, A., Sinha, I., & Hawcutt, D. (2017). Overview of Systematic Reviews of Therapeutic Ranges: Establishing the Threshold of Increased Drug Toxicity. In DRUG SAFETY Vol. 40 (pp. 985). Retrieved from https://www.webofscience.com/
PP-29 Growth hormone dosing in obese children
Peak., Hawcutt., Bellis., Price., McCoy., Newland., & Blair. (2017). PP-29 Growth hormone dosing in obese children. In Archives of Disease in Childhood Vol. 102 (pp. A38.2-A39). BMJ. doi:10.1136/archdischild-2017-esdppp.84
PP-34 Adverse drug reactions in neonates: comparing retrospective spontaneous yellow card reports to prospectively collected reports
Roberts., Hawcutt., & Turner. (2017). PP-34 Adverse drug reactions in neonates: comparing retrospective spontaneous yellow card reports to prospectively collected reports. In Archives of Disease in Childhood Vol. 102 (pp. A28.1-A28). BMJ. doi:10.1136/archdischild-2017-esdppp.59
PP-43 Pharmacogenomics factors relating to ibuprofen and acute kidney injury in paediatric patients: a systematic review
Unsworth., & Hawcutt. (2017). PP-43 Pharmacogenomics factors relating to ibuprofen and acute kidney injury in paediatric patients: a systematic review. In Archives of Disease in Childhood Vol. 102 (pp. A42.1-A42). BMJ. doi:10.1136/archdischild-2017-esdppp.91
Precision dosing to reduce ADRs in children
Hawcutt, D. (2017). Precision dosing to reduce ADRs in children. In DRUG SAFETY Vol. 40 (pp. 1040-1041). Retrieved from https://www.webofscience.com/
Genome-wide association study of asthma exacerbations in European children treated with inhaled corticosteroids
Vijverberg, S. J. H., Hernandez-Pacheco, N., Farzan, N., Francis, B., Flores, C., Schieck, M., . . . Maitland-Van der Zee, A. -H. (2017). Genome-wide association study of asthma exacerbations in European children treated with inhaled corticosteroids. In EUROPEAN RESPIRATORY JOURNAL Vol. 50. doi:10.1183/1393003.congress-2017.PA1817
Genome-wide association study of inhaled corticosteroid response in African-admixed children with asthma
Hernandez-Pacheco, N., Farzan, N., Vijverberg, S. J., Francis, B., Schieck, M., Pirmohamed, M., . . . Pino-Yanes, M. (2017). Genome-wide association study of inhaled corticosteroid response in African-admixed children with asthma. In EUROPEAN RESPIRATORY JOURNAL Vol. 50. doi:10.1183/1393003.congress-2017.PA4688
Protocol for a prospective observational study of adverse drug reactions of anti-epileptic drugs in children in the UK
Egunsola, O., Sammons, H., Ojha, S., Whitehouse, W., Anderson, M., Hawcutt, D. B., & Choonara, I. (2017). Protocol for a prospective observational study of adverse drug reactions of anti-epileptic drugs in children in the UK. BMJ Paediatrics Open. doi:10.1136/bmjpo-2017-000116
17q21 gene variation increases the risk of exacerbations in asthmatic children treated with inhaled corticosteroids: A meta-analysis in the multi-ethnic pica consortium
Farzan, N., Vijverberg, S. J., Hernandez-Pacheco, N., Berce, V., Burchard, E. G., Canino, G., . . . Maitland-Van der Zee, A. H. (2017). 17q21 gene variation increases the risk of exacerbations in asthmatic children treated with inhaled corticosteroids: A meta-analysis in the multi-ethnic pica consortium. In ALLERGY Vol. 72 (pp. 269-270). Retrieved from https://www.webofscience.com/
Genome-Wide Association Study of Asthma Exacerbations in European Children Treated with Inhaled Corticosteroids
Vijverberg, S. J. H., Hernandez-Pacheco, N., Farzan, N., Francis, B., Flores, C., Schieck, M., . . . Maitland-van der Zee, A. -H. (2017). Genome-Wide Association Study of Asthma Exacerbations in European Children Treated with Inhaled Corticosteroids. In PHARMACOEPIDEMIOLOGY AND DRUG SAFETY Vol. 26 (pp. 25-26). Retrieved from https://www.webofscience.com/
NIHR Clinical Research Networks: what they do and how they help paediatric research
Lythgoe, H., Price, V., Poustie, V., Attar, S., Hawcutt, D., Preston, J., & Beresford, M. W. (2017). NIHR Clinical Research Networks: what they do and how they help paediatric research. ARCHIVES OF DISEASE IN CHILDHOOD, 102(8), 755-759. doi:10.1136/archdischild-2016-311057
Growth hormone prescribing and initial BMI SDS: Increased biochemical adverse effects and costs in obese children without additional gain in height
Hawcutt, D. B., Bellis, J., Price, V., Povall, A., Newland, P., Richardson, P., . . . Blair, J. (2017). Growth hormone prescribing and initial BMI SDS: Increased biochemical adverse effects and costs in obese children without additional gain in height. PLoS One, 12(7). doi:10.1371/journal.pone.0181567
Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium
Hawcutt, D. B., & Pirmohamed, M. (2017). Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium. Pharmacogenomics, 18(10), 931-943. doi:10.2217/pgs-2017-0035
Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice.
Cooney, L., Loke, Y. K., Golder, S., Kirkham, J., Jorgensen, A., Sinha, I., & Hawcutt, D. (2017). Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice.. BMC medical research methodology, 17(1). doi:10.1186/s12874-017-0363-z
Optimising the use of medicines to reduce acute kidney injury in children and babies
Oni, L., Hawcutt, D. B., Turner, M. A., Beresford, M. W., McWilliam, S., Barton, C., . . . Antoine, D. J. (2017). Optimising the use of medicines to reduce acute kidney injury in children and babies. Pharmacology and Therapeutics, 174, 55-62. doi:10.1016/j.pharmthera.2017.02.018
17q21 Gene Variance Increases The Risk Of Exacerbations In Asthmatic Children Treated With Inhaled Corticosteroids: A Meta-Analysis In The Pica Consortium
Farzan, N., Vijverberg, S., Hernandez-Pacheco, N., Berce, V., Burchard, E. G., Canino, G., . . . Maitland-van Der Zee, A. -H. (2017). 17q21 Gene Variance Increases The Risk Of Exacerbations In Asthmatic Children Treated With Inhaled Corticosteroids: A Meta-Analysis In The Pica Consortium. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 195. Washington DC. Retrieved from http://gateway.webofknowledge.com/
Using pharmacokinetic modelling to improve prescribing practices of intravenous aminophylline in childhood asthma exacerbations
Cooney, L., McBride, A., Lilley, A., Sinha, I., Johnson, T. N., & Hawcutt, D. B. (2017). Using pharmacokinetic modelling to improve prescribing practices of intravenous aminophylline in childhood asthma exacerbations. PULMONARY PHARMACOLOGY & THERAPEUTICS, 43, 6-11. doi:10.1016/j.pupt.2017.01.007
<i>TPMT</i>, <i>COMT</i> and <i>ACYP2</i> genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity
Thiesen, S., Yin, P., Jorgensen, A. L., Zhang, J. E., Manzo, V., McEvoy, L., . . . Pirmohamed, M. (2017). <i>TPMT</i>, <i>COMT</i> and <i>ACYP2</i> genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity. PHARMACOGENETICS AND GENOMICS, 27(6), 213-222. doi:10.1097/FPC.0000000000000281
2016
Changes in Height and IGF-I SDS in the first year of GH treatment are related to BMI SDS
Price, V., Blair, J., & Hawcutt, D. (n.d.). Changes in Height and IGF-I SDS in the first year of GH treatment are related to BMI SDS. In Endocrine Abstracts. Bioscientifica. doi:10.1530/endoabs.45.p69
Home Urine Sampling as a Research Methodology in Longitudinal Biological Research Studies in Children with Cancer - Patient, Parent and Scientific Perspectives
Cooper, K., Barton, C., Hemsworth, S., Hincks, E., Hawcutt, D., & Pizer, B. (2016). Home Urine Sampling as a Research Methodology in Longitudinal Biological Research Studies in Children with Cancer - Patient, Parent and Scientific Perspectives. In PEDIATRIC BLOOD & CANCER Vol. 63 (pp. S220-S221). Retrieved from https://www.webofscience.com/
Nephrotoxicity in Children Receiving Chemotherapy - 'Omics and Biomarkers
Barton, C., Pizer, B., Hawcutt, D., Pirmohamed, M., Hemsworth, S., & Hincks, E. (2016). Nephrotoxicity in Children Receiving Chemotherapy - 'Omics and Biomarkers. In PEDIATRIC BLOOD & CANCER Vol. 63 (pp. S121-S122). Retrieved from https://www.webofscience.com/
Defining uncontrolled childhood asthma in the global PiCA consortium
Farzan, N., Vijverberg, S. J., Andiappan, A. K., Blanca-Lopez, N., Bonnelykke, K., Campo, P., . . . Maitland-van der Zee, A. H. (2016). Defining uncontrolled childhood asthma in the global PiCA consortium. In EUROPEAN RESPIRATORY JOURNAL Vol. 48. doi:10.1183/13993003.congress-2016.PA4388
Intravenous theophylline levels in children with acute asthma: A systematic review
Cooney, L., Hawcutt, D., & Sinha, I. (2016). Intravenous theophylline levels in children with acute asthma: A systematic review. In EUROPEAN RESPIRATORY JOURNAL Vol. 48. doi:10.1183/13993003.congress-2016.PA314
Aminophylline Dosage In Asthma Exacerbations in Children: A Systematic Review.
Cooney, L., Sinha, I., & Hawcutt, D. (2016). Aminophylline Dosage In Asthma Exacerbations in Children: A Systematic Review. PLOS ONE, 11(8). doi:10.1371/journal.pone.0159965
Defining uncontrolled childhood asthma in the global PiCA consortium
Farzan, N., Vijverberg, S. J., Andiappan, A., Palmer, C. J., Tantisira, K. G., Duijts, L., . . . Maitland-van der Zee, A. H. (2016). Defining uncontrolled childhood asthma in the global PiCA consortium. In ALLERGY Vol. 71 (pp. 53). Retrieved from https://www.webofscience.com/
Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment
Turner, S., Francis, B., Vijverberg, S., Pino-Yanes, M., Maitland-van der Zee, A. H., Basu, K., . . . Asthma, P. C. (2016). Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 138(1), 107-113.E5. doi:10.1016/j.jaci.2015.10.045
Adrenal responses to a low-dose short synacthen test in children with asthma.
Hawcutt, D. B., Jorgensen, A. L., Wallin, N., Thompson, B., Peak, M., Lacy, D., . . . Smyth, R. L. (2016). Adrenal responses to a low-dose short synacthen test in children with asthma (vol 82, pg 648, 2015). CLINICAL ENDOCRINOLOGY, 84(5), 793. doi:10.1111/cen.13069
The Evidence for Intravenous Theophylline Levels between 10-20mg/L in Children Suffering an Acute Exacerbation of Asthma: A Systematic Review
Cooney., sinha., & Hawcutt, D. B. (2016). The Evidence for Intravenous Theophylline Levels between 10-20mg/L in Children Suffering an Acute Exacerbation of Asthma: A Systematic Review. PLoS ONE. doi:10.1371/journal.pone.0153877
G261 Prescribing practices of rituximab in children: a 5-year retrospective review
Price, V., Lythgoe, H., Oni, L., & Hawcutt, D. (2016). G261 Prescribing practices of rituximab in children: a 5-year retrospective review. In Archives of Disease in Childhood Vol. 101 (pp. A144-A145). BMJ. doi:10.1136/archdischild-2016-310863.253
G444 Growth hormone: Analysis of actual and ideal body weight prescribing
Price, V., Hawcutt, D., Fryer, S., Bellis, J., & Blair, J. (2016). G444 Growth hormone: Analysis of actual and ideal body weight prescribing. In Archives of Disease in Childhood Vol. 101 (pp. A262.2-A262). BMJ. doi:10.1136/archdischild-2016-310863.432
G530(P) Loading doses of IV aminophylline: serum concentrations and clinical outcomes
Cooney, L., Hawcutt, D., Sinha, I., Lilley, A., McBride, A., & Lansdale, R. (2016). G530(P) Loading doses of IV aminophylline: serum concentrations and clinical outcomes. In Archives of Disease in Childhood Vol. 101 (pp. A312.3-A313). BMJ. doi:10.1136/archdischild-2016-310863.517
G90(P) Research exposure for UK junior paediatric trainees
Lythgoe, H., Price, V., Beresford, M. W., Peak, M., & Hawcutt, D. (2016). G90(P) Research exposure for UK junior paediatric trainees. In Archives of Disease in Childhood Vol. 101 (pp. A52-A53). BMJ. doi:10.1136/archdischild-2016-310863.87
Precision Dosing in Children
Hawcutt, D. B., Cooney, L., Oni, L., & Pirmohamed, M. (2016). Precision Dosing in Children. EXPERT REVIEW OF PRECISION MEDICINE AND DRUG DEVELOPMENT, 1(1), 69-78. doi:10.1080/23808993.2016.1138845
Design and conduct of early phase drug studies in children: challenges and opportunities
Rieder, M., & Hawcutt, D. (2016). Design and conduct of early phase drug studies in children: challenges and opportunities. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 82(5), 1308-1314. doi:10.1111/bcp.13058
SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR NEONATES AND INFANTS IN THE UK 2001–2010
Hawcutt, D., Maqsood, H., Gomberg, S., Riordan, A., & Turner, M. (2016). SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR NEONATES AND INFANTS IN THE UK 2001–2010. Archives of Disease in Childhood, 101(1), e1.43-e1. doi:10.1136/archdischild-2015-310148.48
SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR TRANSPLACENTAL AND TRANSMAMMARY ROUTES IN THOSE ≤1 YEAR IN THE UK 2001–2010
Russell, N. -J., Turner, M., & Hawcutt, D. (2016). SPONTANEOUS ADVERSE DRUG REACTION REPORTS FOR TRANSPLACENTAL AND TRANSMAMMARY ROUTES IN THOSE ≤1 YEAR IN THE UK 2001–2010. Archives of Disease in Childhood, 101(1), e1.21-e1. doi:10.1136/archdischild-2015-310148.28
Spontaneous adverse drug reaction reports for neonates and infants in the UK 2001-2010: content and utility analysis
Hawcutt, D. B., Russell, N. J., Maqsood, H., Kouranloo, K., Gomberg, S., Waitt, C., . . . Turner, M. A. (2016). Spontaneous adverse drug reaction reports for neonates and infants in the UK 2001-2010: content and utility analysis. British journal of clinical pharmacology, 82(06), 1601-1612. doi:10.1111/bcp.13067
2015
UK service level audit of insulin pump therapy in paediatrics
Ghatak, A., Paul, P., Hawcutt, D. B., White, H. D., Furlong, N. J., Saunders, S., . . . Weston, P. J. (2015). UK service level audit of insulin pump therapy in paediatrics. DIABETIC MEDICINE, 32(12), 1652-1657. doi:10.1111/dme.12782
Between patient and inter-time point variability in salivary cortisone: cortisol ratios
Park, J., Lancaster, G., Titman, A., Peak, M., Newlands, P., Collingwood, C., . . . Blair, J. (n.d.). Between patient and inter-time point variability in salivary cortisone: cortisol ratios. Endocrine Abstracts. doi:10.1530/endoabs.39.ep2
When to report adverse drug reactions in children?
Barton, C., & Hawcutt, D. B. (2015). When to report adverse drug reactions in children?. ARCHIVES OF DISEASE IN CHILDHOOD, 100(7), 682-683. doi:10.1136/archdischild-2014-307906
Pharmacogenetic Markers of Drug Efficacy and Toxicity.
Yip, V., Hawcutt, D., & Pirmohamed, M. (2015). Pharmacogenetic Markers of Drug Efficacy and Toxicity.. Clinical pharmacology and therapeutics, 98(1), 61-70. doi:10.1002/cpt.135
ST13 polymorphisms and their effect on exacerbations in steroid‐treated asthmatic children and young adults
Vijverberg, S. J. H., Koster, E. S., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., . . . Maitland-van der Zee, A. H. (2015). ST13 polymorphisms and their effect on exacerbations in steroid‐treated asthmatic children and young adults. Clinical and Experimental Allergy, 45(6), 1051-1059. doi:10.1111/cea.12492
Adrenal responses to a low-dose short synacthen test in children with asthma
Hawcutt, D. B., Jorgensen, A. L., Wallin, N., Thompson, B., Peak, M., Lacy, D., . . . Smyth, R. L. (2015). Adrenal responses to a low-dose short synacthen test in children with asthma. CLINICAL ENDOCRINOLOGY, 82(5), 648-656. doi:10.1111/cen.12655
ACUTE KIDNEY INJURY IN PAEDIATRIC ONCOLOGY PATIENTS RECEIVING CISPLATIN
Barton, C., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2015). ACUTE KIDNEY INJURY IN PAEDIATRIC ONCOLOGY PATIENTS RECEIVING CISPLATIN. PEDIATRIC BLOOD & CANCER, 62, S302-S303. Retrieved from https://www.webofscience.com/
Comparing paediatric intravenous phenytoin doses using physiologically based pharmacokinetic (PBPK) modelling software
Batchelor, H., Appleton, R., & Hawcutt, D. B. (2015). Comparing paediatric intravenous phenytoin doses using physiologically based pharmacokinetic (PBPK) modelling software. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 33, 8-12. doi:10.1016/j.seizure.2015.10.006
Implementation of a clinical protocol for measuring early morning salivary cortisol and cortisone, as a screening test for asthmatics at high risk of adrenal crisis
Trinick, R., Doyle, C., McNamara, P., Hawcutt, D., Kelly, E., Worrall, V., & Blair, J. (2015). Implementation of a clinical protocol for measuring early morning salivary cortisol and cortisone, as a screening test for asthmatics at high risk of adrenal crisis. In CLINICAL AND EXPERIMENTAL ALLERGY Vol. 45 (pp. 1908). Retrieved from https://www.webofscience.com/
MARKERS OF TUBULAR RENAL INJURY IN CHILDREN WITH CANCER RECEIVING CISPLATIN AND/OR IFOSFAMIDE
Barton, C., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2015). MARKERS OF TUBULAR RENAL INJURY IN CHILDREN WITH CANCER RECEIVING CISPLATIN AND/OR IFOSFAMIDE. PEDIATRIC BLOOD & CANCER, 62, S302. Retrieved from https://www.webofscience.com/
2014
Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.
Hawcutt, D., Ghani, A., Sutton, L., Jorgensen, A., Zhang, E., Murray, M., . . . Pirmohamed, M. (2014). Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.. The Pharmacogenomics Journal, 14(6), 542-548. doi:10.1038/tpj.2014.31
Adverse drug reactions in neonates: could we be documenting more?
Hawcutt, D. B., O'Connor, O., & Turner, M. A. (2014). Adverse drug reactions in neonates: could we be documenting more?. EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 7(6), 807-820. doi:10.1586/17512433.2014.956090
Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading
Piper, J. D., Hawcutt, D. B., Verghese, G. K., Spinty, S., Newland, P., & Appleton, R. (2014). Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading. ARCHIVES OF DISEASE IN CHILDHOOD, 99(6), 585-586. doi:10.1136/archdischild-2013-305093
G335(P) Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading dose
Piper, J., Hawcutt, D., Verghese, G., Spinty, S., Newland, P., & Appleton, R. (2014). G335(P) Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading dose. Archives of Disease in Childhood, 99(Suppl 1), A138. doi:10.1136/archdischild-2014-306237.318
G365 Medical management of neuropathic pain in complex regional pain syndromes
Hawcutt, D., Whitby, T., & Cleary, G. (2014). G365 Medical management of neuropathic pain in complex regional pain syndromes. Archives of Disease in Childhood, 99(Suppl 1), A150-A151. doi:10.1136/archdischild-2014-306237.348
G409(P) National audit of analgesia post tonsillectomy
O'Connor, O., Hawcutt, D., & Donne, A. (2014). G409(P) National audit of analgesia post tonsillectomy. Archives of Disease in Childhood, 99(Suppl 1), A172. doi:10.1136/archdischild-2014-306237.390
A randomized trial of hyperglycemic control in pediatric intensive care.
Macrae, D., Grieve, R., Allen, E., Sadique, Z., Morris, K., Pappachan, J., . . . CHiP Investigators. (2014). A randomized trial of hyperglycemic control in pediatric intensive care.. The New England journal of medicine, 370(2), 107-118. doi:10.1056/nejmoa1302564
Assessing the reliability of exome sequencing to detect the filaggrin null mutations R501X and 2282del4
Thompson, B., Hawcutt, D., Carr, D., Bloch, K., Swale, A., Smyth, R., & Pirmohamed, M. (2014). Assessing the reliability of exome sequencing to detect the filaggrin null mutations R501X and 2282del4. In BRITISH JOURNAL OF DERMATOLOGY Vol. 171 (pp. 115-116). Retrieved from https://www.webofscience.com/
Early morning salivary cortisol and cortisone, and adrenal responses to a simplified low-dose short Synacthen test in children with asthma
Blair, J., Lancaster, G., Titman, A., Peak, M., Newlands, P., Collingwood, C., . . . Couriel, J. (2014). Early morning salivary cortisol and cortisone, and adrenal responses to a simplified low-dose short Synacthen test in children with asthma. CLINICAL ENDOCRINOLOGY, 80(3), 376-383. doi:10.1111/cen.12302
Efficacy and tolerability of zolmitriptan oro-dispersible wafer in treatment of childhood migraine
Kerrison, C., Wright, F., Piper, J., Kumar, R., & Hawcutt, D. B. (2014). Efficacy and tolerability of zolmitriptan oro-dispersible wafer in treatment of childhood migraine. EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE, 21(2), 84-86. doi:10.1136/ejhpharm-2013-000347
Improving the quality of written information available at weekends in a paediatric hospital: the TRANSMIT sheet.
Hawcutt, D., Green, J., Durand, C., Mehta, F., Christopherson, M., & Sinha, I. (2014). Improving the quality of written information available at weekends in a paediatric hospital: the TRANSMIT sheet.. BMJ quality improvement reports, 2(2), u202302.w1137. doi:10.1136/bmjquality.u202302.w1137
2013
The restrictions to the use of codeine and dilemmas about safe alternatives
Carter, B., Hawcutt, D. B., & Arnott, J. (2013). The restrictions to the use of codeine and dilemmas about safe alternatives. JOURNAL OF CHILD HEALTH CARE, 17(4), 335-337. doi:10.1177/1367493513513663
Paediatric pharmacogenomics: an overview
Hawcutt, D. B., Thompson, B., Smyth, R. L., & Pirmohamed, M. (2013). Paediatric pharmacogenomics: an overview. Archives of Disease in Childhood, 98(3), 232-237. doi:10.1136/archdischild-2012-302852
Paediatric pharmacogenomics: an overview
Hawcutt, D. B., Thompson, B., Smyth, R. L., & Pirmohamed, M. (2013). Paediatric pharmacogenomics: an overview. ARCHIVES OF DISEASE IN CHILDHOOD, 98(3), 232-237. doi:10.1136/archdischild-2012-302852
2012
VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN
Thompson, B., Hawcutt, D. B., Carr, D. F., Jorgensen, A. L., Smyth, R. L., & Pirmohamed, M. (2012). VARIATION AT GLCCI1: ASSOCIATION WITH INCREASED STEROID DOSE BUT NOT ADRENAL SUPPRESSION IN ASTHMATIC CHILDREN. THORAX, 67, A17. doi:10.1136/thoraxjnl-2012-202678.037
Decreased milk drinking causing flecainide toxicity in an older child.
Thompson, B., Mangat, J., Barton, C., & Hawcutt, D. B. (2012). Decreased milk drinking causing flecainide toxicity in an older child.. BMJ case reports, 2012, bcr0220125810. doi:10.1136/bcr.02.2012.5810
Reported paediatric adverse drug reactions in the UK 2000-2009
Hawcutt, D. B., Mainie, P., Riordan, A., Smyth, R. L., & Pirmohamed, M. (2012). Reported paediatric adverse drug reactions in the UK 2000-2009. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 73(3), 437-446. doi:10.1111/j.1365-2125.2011.04113.x
Acute kidney injury in paediatric cancer patients receiving cisplatin
Barton, C., Oates, A., Hawcutt, D., Pirmohamed, M., & Pizer, B. (2012). Acute kidney injury in paediatric cancer patients receiving cisplatin. Journal of the Royal College of Physicians Edinburgh, 42(Sup, 36�50.
Reported Paediatric Adverse Drug Reactions in the UK 2000-2009
Hawcutt, D., Mainie, P., Andrew, R., Smyth, R. L., & Pirmohamed, M. (2012). Reported Paediatric Adverse Drug Reactions in the UK 2000-2009. British Journal of Clinical Pharmacology, 73(3), 437-446.
2011
Treatment of neonatal sepsis with intravenous immune globulin.
INIS Collaborative Group., Brocklehurst, P., Farrell, B., King, A., Juszczak, E., Darlow, B., . . . Tarnow-Mordi, W. (2011). Treatment of neonatal sepsis with intravenous immune globulin.. The New England journal of medicine, 365(13), 1201-1211. doi:10.1056/nejmoa1100441
Serum phenytoin concentrations in paediatric patients following intravenous loading
Hawcutt, D. B., Sampath, S., Timmis, A., Newland, V., Newland, P., & Appleton, R. (2011). Serum phenytoin concentrations in paediatric patients following intravenous loading. ARCHIVES OF DISEASE IN CHILDHOOD, 96(9), 883-884. doi:10.1136/adc.2011.215269
'Lest we forget ...'
Mainie, P., & Hawcutt, D. (2011). 'Lest we forget ...'. ARCHIVES OF DISEASE IN CHILDHOOD, 96(7), 699. doi:10.1136/adc.2010.208363
Twin-twin confusion syndrome: Blood chimerism in opposite sex dizygotic twins
Hawcutt, D., Hammond, B., Sibbring, J., Gokhale, D., Ellis, I., Bricker, L., & Subhedar, N. (2011). Twin-twin confusion syndrome: Blood chimerism in opposite sex dizygotic twins. JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 31(5), 446-448. doi:10.3109/01443615.2011.570813
Adverse drug reactions in children: reports to the UK yellow card scheme 2000-2009
Hawcutt, D. B., Mainie, P., Appleton, R., Smyth, R., & Pirmohamed, M. (2011). Adverse drug reactions in children: reports to the UK yellow card scheme 2000-2009. Archives of Disease in Childhood, 96(Supplement 1), A57. doi:10.1136/adc.2011.212563.130
"Lest we forget" Letter
Mainie, P., & Hawcutt, D. B. (2011). "Lest we forget" Letter. Archives of Disease in Childhood, 96, 699.
Reported Paediatric Adverse Drug Reactions in the UK 2000-2009
Hawcutt, D. B., Mainie, P., Appleton, R., Smyth, R. L., & Pirmohamed, M. (2011). Reported Paediatric Adverse Drug Reactions in the UK 2000-2009. Archives of Disease in Childhood, 96, A5.
Reports to the UK Yellow Card Scheme 2000-2009 for medications used in paediatric rheumatology
Hawcutt, D. B., Pain, C., Mulholland, R., Cann, L. M., Cleary, G., Beresford, M. W., & Baildam, E. (2011). Reports to the UK Yellow Card Scheme 2000-2009 for medications used in paediatric rheumatology. Pediatric rheumatology online journal, 9(Suppl 1), P237. doi:10.1186/1546-0096-9-s1-p237
Serum Levels of Phenytoin in Paediatric Patients following an 18mg/kg Intravenous Loading Dose.
Hawcutt, D. B., Sampath, S., Timmis, A., Newland, V., Newland, P., & Appleton, R. (2011). Serum Levels of Phenytoin in Paediatric Patients following an 18mg/kg Intravenous Loading Dose.. Archives of Disease in Childhood, 96(9), 883-884.
Steroid dose, age and gender affect adrenal responses to a low dose short Synacthen test in children with asthma
Hawcutt, D. B., Jorgensen, A. L., Gardner, C., Peak, M., Couriel, J., Lacy, D., . . . Blair, J. (2011). Steroid dose, age and gender affect adrenal responses to a low dose short Synacthen test in children with asthma. Endocrine Abstracts, 27, 32.
Sulthiame in refractory paediatric epilepsies: An experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit
Swiderska, N., Hawcutt, D., Eaton, V., Stockton, F., Kumar, R., Kneen, R., & Appleton, R. (2011). Sulthiame in refractory paediatric epilepsies: An experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 20(10), 805-808. doi:10.1016/j.seizure.2011.08.006
2010
USE OF STEROIDS IN INOTROPE RESISTANT SEPSIS AND AT EXTUBATION IN UK PAEDIATRIC INTENSIVE CARE UNITS - TELEPHONE AUDIT
Hawcutt, D., Sharpe, J., & Parkins, K. (2010). USE OF STEROIDS IN INOTROPE RESISTANT SEPSIS AND AT EXTUBATION IN UK PAEDIATRIC INTENSIVE CARE UNITS - TELEPHONE AUDIT. PEDIATRIC RESEARCH, 68, 626-627. doi:10.1203/00006450-201011001-01265
Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates
Hawcutt, D. B., Rose, A. C., Fuerst-Recktenwald, S., Nunn, T., & Turner, M. A. (2010). Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates. In GUIDE TO PAEDIATRIC DRUG DEVELOPMENT AND CLINICAL RESEARCH (pp. 97-110). Retrieved from https://www.webofscience.com/
Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon (vol 135, pg 205, 2008)
Lindley, R. M., Hawcutt, D. B., Connell, M. G., & Almond, S. L. (2010). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon (vol 135, pg 205, 2008). GASTROENTEROLOGY, 138(2), 792. Retrieved from https://www.webofscience.com/
MUCOSITIS PREVENTION: EFFICACY OF SUPERSATURATED CALCIUM AND PHOSPHATE SOLUTION IN HIGH RISK PAEDIATRIC ONCOLOGY PATIENTS
Hawcutt, D., Awogbemi, O., Bell, E., & McDowell, H. (2010). MUCOSITIS PREVENTION: EFFICACY OF SUPERSATURATED CALCIUM AND PHOSPHATE SOLUTION IN HIGH RISK PAEDIATRIC ONCOLOGY PATIENTS. PEDIATRIC BLOOD & CANCER, 55(5), 951. Retrieved from https://www.webofscience.com/
Mucositis Prevention: Efficacy of Supersaturated Calcium and Phosphate Solution in High Risk Paediatric Oncology Patients
Hawcutt, D. B., Awogbemi, O., Bell, E., & McDowell, H. (2010). Mucositis Prevention: Efficacy of Supersaturated Calcium and Phosphate Solution in High Risk Paediatric Oncology Patients. Paediatric Blood and Cancer, 5(55), 951.
Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates
Hawcutt, D. B., Rose, A. C., Fuerst-Recktenwald, S., Nunn, T., & Turner, M. A. (2010). Points to Consider when Planning the Collection of Blood or Tissue Samples in Clinical Trials of Investigational Medicinal Products in Children, Infants and Neonates. In Guide to Paediatric Drug Development and Clinical Research (pp. 97-110). KARGER. doi:10.1159/000315578
Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates
Hawcutt, D. B., Rose, A. C., Fuerst-Rectenwald, S., Nunn, A. J., & Turner, M. A. (2010). Points to consider when planning the collection of blood or tissue samples in clinical trials of investigational medicinal products in children, infants and neonates. In K. Rose, & J. van den Anker (Eds.), Guide to Paediatric Drug Development and Clinial Research (pp. 96-110). Basel: Karger.
2009
Prioritising neonatal medicines research: UK Medicines for Children Research Network scoping survey
Turner, M. A., Lewis, S., Hawcutt, D. B., & Field, D. (2009). Prioritising neonatal medicines research: UK Medicines for Children Research Network scoping survey. BMC PEDIATRICS, 9. doi:10.1186/1471-2431-9-50
Properties of secondary and tertiary human enteric nervous system neurospheres
Lindley, R. M., Hawcutt, D. B., Connell, M. G., Edgar, D. H., & Kenny, S. E. (2009). Properties of secondary and tertiary human enteric nervous system neurospheres. JOURNAL OF PEDIATRIC SURGERY, 44(6), 1249-1256. doi:10.1016/j.jpedsurg.2009.02.048
Functional analysis of enteric nervous system progenitor cells
Edgar, D. H., Lindley, R. M., Hawcutt, D. B., Theocharatos, S., & Kenny, S. E. (2009). Functional analysis of enteric nervous system progenitor cells. Neurogastroenterology and Motility, 2(21), XIII.
Functional analysis of enteric nervous system progenitor cells
Edgar, D., Lindley, R., Hawcutt, D., Theocharatos, S., & Kenny, S. (2009). Functional analysis of enteric nervous system progenitor cells. In NEUROGASTROENTEROLOGY AND MOTILITY Vol. 21 (pp. XIII). Retrieved from https://www.webofscience.com/
The Effects of Enteric Nervous System Stem Cell Transplantation on the Behaviour of Cultured Samples of Mammalian Distal Colon
Hawcutt, D. B. (2009). The Effects of Enteric Nervous System Stem Cell Transplantation on the Behaviour of Cultured Samples of Mammalian Distal Colon. (PhD Thesis, University of Liverpool).
2008
Drug development for children: How is pharma tackling an unmet need?
Hawcutt, D. B., & Smyth, R. L. (2008). Drug development for children: How is pharma tackling an unmet need?. IDRUGS, 11(11), 502-507.
Drug development for children: How is pharma tackling an unmet need?
Hawcutt, D. B., & Smyth, R. L. (2008). Drug development for children: How is pharma tackling an unmet need?. In IDRUGS Vol. 11 (pp. 502-507). Retrieved from https://www.webofscience.com/
Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon.
Lindley, R., Hawcutt, D., Connell, G., Almond, S., Vannucchi, M. -G., Faussone-Pellegrini, M. S., . . . Kenny, S. (2008). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon.. Gastroenterology, 135(1), 205-216.
The new European regulation on pediatric medicines: regulatory perspective.
Hawcutt, D. B., & Smyth, R. L. (2008). The new European regulation on pediatric medicines: regulatory perspective.. Paediatric drugs, 10(3), 143-146. doi:10.2165/00148581-200810030-00002
One size does not fit all: getting drug doses right for children
Hawcutt, D. B., & Smyth, R. L. (2008). One size does not fit all: getting drug doses right for children. ARCHIVES OF DISEASE IN CHILDHOOD, 93(3), 190-191. doi:10.1136/adc.2007.127951
Chapter 9: Advances towards the Development of a Stem Cell Therapy for Hirschsprung's Disease
Hawcutt, D. B., Lindley, R. M., Kenny, S. E., & Edgar, D. H. (2008). Chapter 9: Advances towards the Development of a Stem Cell Therapy for Hirschsprung's Disease. In Stem Cell Research Progress (pp. 137-157). New York: Nova Science Publishers.
Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon
Lindley, R. M., Hawcutt, D. B., Connell, M. G., Almond, S. N., Vannucchi, M. -G., Faussone-Pellegrini, M. S., . . . Kenny, S. E. (2008). Human and mouse enteric nervous system neurosphere transplants regulate the function of aganglionic embryonic distal colon. GASTROENTEROLOGY, 135(1), 205-216. doi:10.1053/j.gastro.2008.03.035
Paediatric Pharmacogenomics - Challenges and Opportunities. 2008; 2(1): 13-15
Hawcutt, D. B., & Pirmohamed, M. (2008). Paediatric Pharmacogenomics - Challenges and Opportunities. 2008; 2(1): 13-15. European Paediatrics, 2(1), 13-15.
Points to consider when planning the collection of blood samples in clinical trials of investigational medicinal products.
Hawcutt, D. B., Rose, A. C., Nunn, T., & Turner, M. A. (2008). Points to consider when planning the collection of blood samples in clinical trials of investigational medicinal products.. Liverpool: Medicines for Children Research Network. Retrieved from http://ctuprod.liv.ac.uk/mcrnweb/images/mcrn_guide_for_blood_sampling_v1.0.pdf
The New European Regulation on Paediatric Medicines: Regulatory Perspective
Hawcutt, D. B., & Smyth, R. L. (2008). The New European Regulation on Paediatric Medicines: Regulatory Perspective. Pediatric Drugs, 10(3), 143-146.
2007
Advances towards the development of a stem cell therapy for Hirschsprung's disease
Hawcutt, D. B., Lindley, R. M., Kenny, S. E., & Edgar, D. H. (2007). Advances towards the development of a stem cell therapy for Hirschsprung's disease. Journal of Stem Cells, 2(2), 105-119.
Advances towards a stem cell therapy for Hirschprung's disease
Hawcutt, D. L. R. K. S., & Edgar, D. H. (2007). Advances towards a stem cell therapy for Hirschprung's disease. Journal of Stem Cells, 2, 41-47.
Functional rescue following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease occurs via Nitric Oxide signalling
Hawcutt, D. B., Lindley, R. M., Edgar, D. H., & Kenny, S. E. (2007). Functional rescue following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease occurs via Nitric Oxide signalling. Journal of Perinatology, 27, 626.
Restoration of function following mouse and human enteric nervous system transplants into an <i>in vitro</i> model of Hirschsprung's disease
Hawcutt, D., Lindley, R., Edgar, D., & Kenny, S. (2007). Restoration of function following mouse and human enteric nervous system transplants into an <i>in vitro</i> model of Hirschsprung's disease. GASTROENTEROLOGY, 132(4), A577. Retrieved from https://www.webofscience.com/
Restoration of normal function following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease
Hawcutt, D. B., Lindley, R. M., Edgar, D. H., & Kenny, S. E. (2007). Restoration of normal function following mouse enteric nervous system transplant into an in vitro model of Hirschsprung's disease. Archives of Disease in Childhood, 92(Suppl), A4-A5.
2005
Workload Implications Of Obesity In The Paediatric Outpatient Clinic
Hawcutt, D. B., Casson, D., Williams, S., & Blair, J. C. (2005). Workload Implications Of Obesity In The Paediatric Outpatient Clinic. Archives of Disease in Childhood, 90(Suppl), A14-A18.