Publications
2022
Impact of fluoroquinolones and aminoglycosides on<i> P.</i><i> aeruginosa</i> virulence factor production and
Foulkes, D. M., McLean, K., Sloniecka, M., Rustidge, S., Byrne, D. P., Haneef, A. S., . . . Kaye, S. B. (2022). Impact of fluoroquinolones and aminoglycosides on<i> P.</i><i> aeruginosa</i> virulence factor production and. BIOCHEMICAL JOURNAL, 479(24), 2511-2527. doi:10.1042/BCJ20220527
P-18 Impact of fluoroquinolones and aminoglycosides on P<i>. aeruginosa</i> virulence factor production and cytotoxicity.
Kaye, S., McLean, K., Foulkes, D. M., Sloniecka, M., Byrne, D., Haneef, A. S., . . . Fernig, D. G. (2022). P-18 Impact of fluoroquinolones and aminoglycosides on P<i>. aeruginosa</i> virulence factor production and cytotoxicity.. In BMJ open ophthalmology Vol. 7 (pp. A6). doi:10.1136/bmjophth-2022-bcm.15
2021
Bacterial keratitis: identifying the areas of clinical uncertainty
Tuft, S., Somerville, T. F., Li, J. -P. O., Neal, T., De, S., Horsburgh, M. J., . . . Kaye, S. (2021). Bacterial keratitis: identifying the areas of clinical uncertainty. Progress in Retinal and Eye Research, 101031. doi:10.1016/j.preteyeres.2021.101031
A pipeline to evaluate inhibitors of the <i>Pseudomonas</i> <i>aeruginosa</i> exotoxin U
Foulkes, D. M., McLean, K., Zheng, Y., Sarsby, J., Haneef, A. S., Fernig, D. G., . . . Kaye, S. B. (2021). A pipeline to evaluate inhibitors of the <i>Pseudomonas</i> <i>aeruginosa</i> exotoxin U. BIOCHEMICAL JOURNAL, 478(3), 647-668. doi:10.1042/BCJ20200780
2019
<i>Pseudomonas aeruginosa</i> Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections
Foulkes, D. M., McLean, K., Haneef, A. S., Fernig, D. G., Winstanley, C., Berry, N., & Kaye, S. B. (2019). <i>Pseudomonas aeruginosa</i> Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections. MICROORGANISMS, 7(12). doi:10.3390/microorganisms7120707
Comb-like dextran copolymers: A versatile strategy to coat highly porous MOF nanoparticles with a PEG shell.
Cutrone, G., Qiu, J., Menendez-Miranda, M., Casas-Solvas, J. M., Aykaç, A., Li, X., . . . Gref, R. (2019). Comb-like dextran copolymers: A versatile strategy to coat highly porous MOF nanoparticles with a PEG shell.. Carbohydrate polymers, 223, 115085. doi:10.1016/j.carbpol.2019.115085
Combinatorial Drug Therapy: Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections (Part. Part. Syst. Charact. 3/2019)
Li, X., Semiramoth, N., Hall, S., Tafani, V., Josse, J., Laurent, F., . . . Gref, R. (2019). Combinatorial Drug Therapy: Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections (Part. Part. Syst. Charact. 3/2019). Particle & Particle Systems Characterization, 36(3). doi:10.1002/ppsc.201970009
Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections
Li, X., Semiramoth, N., Hall, S., Tafani, V., Josse, J., Laurent, F., . . . Gref, R. (2019). Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections. Particle & Particle Systems Characterization, 36(3). doi:10.1002/ppsc.201800360
2018
Biochemical analysis of Tribbles 2 pseudokinase using repurposed kinase inhibitors
Foulkes, D. M. (2018, September 28). Biochemical analysis of Tribbles 2 pseudokinase using repurposed kinase inhibitors.
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells
Foulkes, D. M., Byrne, D. P., Yeung, W., Shrestha, S., Bailey, F. P., Ferries, S., . . . Eyers, P. A. (2018). Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells. SCIENCE SIGNALING, 11(549), 14 pages. doi:10.1126/scisignal.aat7951
2017
Pseudokinases: update on their functions and evaluation as new drug targets
Byrne, D. P., Foulkes, D. M., & Eyers, P. A. (2017). Pseudokinases: update on their functions and evaluation as new drug targets. FUTURE MEDICINAL CHEMISTRY, 9(2), 245-265. doi:10.4155/fmc-2016-0207
2015
Tribbles pseudokinases: novel targets for chemical biology and drug discovery?
Foulkes, D. M., Byrne, D. P., Bailey, F. P., & Eyers, P. A. (2015). Tribbles pseudokinases: novel targets for chemical biology and drug discovery?. BIOCHEMICAL SOCIETY TRANSACTIONS, 43, 1095-1103. doi:10.1042/BST20150109