Research
Research Interest 1
Insulin resistance, obesity, insulin signalling, AMPK, skeletal muscle, NASH, PCOS, magnetic resonance spectroscopy, MEN
Research grants
Multi-organ abnormality prevalence in type 2 diabetes mellitus
INNOVATE UK (UK)
April 2019 - March 2022
Randomised, single blind study to assess efficacy of combination therapy of dapagliflozin with exanitide LAR versus exanatide LAR monotherapy in obese (BMI>35 kg/m2) patients with type 2 diabetes mellitus (RESILIENT)
ASTRAZENECA LIMITED (UK)
July 2016 - December 2024
Prospective assessment of impact on length of hospital stay, outcome and cost benefit of tolvaptan in patients with aneurysmal subarachnoid haemorrhage with SIADH associated hyponatraemia in a large tertiary neurosurgical centre
OTSUKA PHARMACEUTICAL EUROPE LTD (UK)
June 2011 - May 2013
The effects of exercise training on visceral fat, insulin sensitivity, beta cell function and triglyceride kinetics in patients with non-alcoholic fatty liver disease (NAFLD)
EUROPEAN FOUNDATION FOR THE STUDY OF DIABETES (GERMANY)
October 2008 - March 2013
Characterising the metabolic disruption caused by brief periods of reduced physical activity in people with a family history of type 2 diabetes mellitus (T2DM).
DIABETES UK (UK)
March 2014 - December 2017
The effect of AICAR on skeletal muscle glucose uptake in type 2 diabetes
PEEL MEDICAL RESEARCH TRUST (UK)
February 2008 - January 2009
VIP 2007/08
WELLCOME TRUST (UK)
October 2007 - September 2008
Effects of non-nutritive sweetened (NNS) beverages on appetite during active weight loss: Does the consumption of low calorie sweetened beverages (versus water) support or undermine weight management through effects on hunger, satiety, liking, wanting or changes in food preference?
AMERICAN BEVERAGE ASSOCIATION (ABA) (USA)
November 2014 - December 2024
Zinc-alpha2-glycoprotein (ZAG): A ‘friend or foe’ in obesity-induced insulin resistance and non-alcoholic fatty liver disease (NAFLD)?
DIABETES RESEARCH AND WELLNESS FOUNDATION (UK)
June 2010 - May 2011
Pancreatic and extra-pancreatic effects of glucose-dependent insulinotropic polypeptide (GIP) in humans in health and type 2 diabetes mellitus
THE NOVO NORDISK UK RESEARCH FOUNDATION (UK)
May 2010 - April 2012
Research collaborations
Professor Malcolm Jackson
Dr Graham Kemp
Estimation of intrahepatic fat and intramyocellular fat in insulin resistant states
Professor Paul Trayhurn
Professor John Wilding
Examining aspects of whole body and muscle physiology in obesity
Dr Martin Lombard
Royal Liverpool and Broadgreen University Hospital NHS Trust
Involved in investigation into insulin resistance in NASH and hepatitis C
Professor D.Grahame Hardie
The University of Dundee
Analysis of AMPK activity
Dr Calum Sutherland
The University of Dundee
Molecular biology of insulin resistance
Professor Michael Rennie
The University of Nottingham
Examination of muscle protein synthesis