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Claire Eyers

Professor Claire Eyers
BSc, PhD, FRSC

Associate Pro-Vice-Chancellor for Research and Impact (HLS) and Professor of Biological Mass Spectrometry
Biochemistry, Cell and Systems Biology

Publications

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2024

PSKH1 kinase activity is differentially modulated via allosteric binding of Ca<sup>2+</sup>sensor proteins

DOI
10.1101/2024.10.20.619163
Preprint

Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva

DOI
10.26434/chemrxiv-2024-4t52c
Preprint

Celebrating Women in Proteomics and Metabolomics.

Cristea, I. M., & Eyers, C. E. (2024). Celebrating Women in Proteomics and Metabolomics.. Journal of proteome research, 23(8), 2675-2679. doi:10.1021/acs.jproteome.4c00613

DOI
10.1021/acs.jproteome.4c00613
Journal article

Activation loop phosphorylation of Cdk11 is restrained by PNUTS-PP1 and regulates Cdk11 activity and function

DOI
10.1101/2024.05.08.592654
Preprint

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

Bendzunas, G. N., Byrne, D. P., Shrestha, S., Daly, L. A., Oswald, S. O., Katiyar, S., . . . Kannan, N. (2024). Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. doi:10.7554/elife.92536.3

DOI
10.7554/elife.92536.3
Journal article

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

DOI
10.7554/elife.92536
Preprint

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

DOI
10.7554/elife.92536.2
Preprint

2023

Mass Spectrometric Analysis of the Active Site Tryptic Peptide of Recombinant <i>O</i><sup>6</sup>-Methylguanine-DNA Methyltransferase Following Incubation with Human Colorectal DNA Reveals the Presence of an <i>O</i><sup>6</sup>-Alkylguanine Adductome.

Abdelhady, R., Senthong, P., Eyers, C. E., Reamtong, O., Cowley, E., Cannizzaro, L., . . . Povey, A. C. (2023). Mass Spectrometric Analysis of the Active Site Tryptic Peptide of Recombinant <i>O</i><sup>6</sup>-Methylguanine-DNA Methyltransferase Following Incubation with Human Colorectal DNA Reveals the Presence of an <i>O</i><sup>6</sup>-Alkylguanine Adductome.. Chemical research in toxicology, 36(12), 1921-1929. doi:10.1021/acs.chemrestox.3c00207

DOI
10.1021/acs.chemrestox.3c00207
Journal article

Custom Workflow for the Confident Identification of Sulfotyrosine-Containing Peptides and Their Discrimination from Phosphopeptides.

Daly, L. A., Byrne, D. P., Perkins, S., Brownridge, P. J., McDonnell, E., Jones, A. R., . . . Eyers, C. E. (2023). Custom Workflow for the Confident Identification of Sulfotyrosine-Containing Peptides and Their Discrimination from Phosphopeptides.. Journal of proteome research, 22(12), 3754-3772. doi:10.1021/acs.jproteome.3c00425

DOI
10.1021/acs.jproteome.3c00425
Journal article

MicroAge Mission: Examining the Effects of Microgravity and Electrical Stimulation on the Proteome of Human Tissue-Engineered Muscle Constructs

Jones, S., Shigdar, S., Hemmings, K., Hoettges, K., Henstock, J., McArdle, C., . . . McArdle, A. (2023). MicroAge Mission: Examining the Effects of Microgravity and Electrical Stimulation on the Proteome of Human Tissue-Engineered Muscle Constructs. Free Radical Biology and Medicine, 208, S55. doi:10.1016/j.freeradbiomed.2023.10.125

DOI
10.1016/j.freeradbiomed.2023.10.125
Journal article

18P AURKB inhibition radiosensitises NSCLC by altering mitotic fate

Egerton, K., Mitchell, T. A., Gravells, P., Katse, R., Fisher, M., Muthana, M., . . . Bryant, H. E. (2023). 18P AURKB inhibition radiosensitises NSCLC by altering mitotic fate. ESMO Open, 8(1), 101664. doi:10.1016/j.esmoop.2023.101664

DOI
10.1016/j.esmoop.2023.101664
Journal article

Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases.

Venkat, A., Watterson, G., Byrne, D. P., O'Boyle, B., Shrestha, S., Gravel, N., . . . Kannan, N. (2023). Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases.. bioRxiv. doi:10.1101/2023.03.29.534689

DOI
10.1101/2023.03.29.534689
Journal article

Mapping distinct vasodilator-induced phosphorylation patterns in human vascular smooth muscle: A quantitative phosphoproteomic approach

Sloniecka, M., Harris, J., Eyers, C., & Dart, C. (2023). Mapping distinct vasodilator-induced phosphorylation patterns in human vascular smooth muscle: A quantitative phosphoproteomic approach. Physiology, 38(S1). doi:10.1152/physiol.2023.38.s1.5732062

DOI
10.1152/physiol.2023.38.s1.5732062
Journal article

2022

Want to Publish in <i>JPR</i>? This Is What You Need to Know!

Yates, J. R., Cristea, I. M., Dong, M. -Q., Eyers, C. E., LaBaer, J., Li, J. V., . . . Slavov, N. (2022). Want to Publish in <i>JPR</i>? This Is What You Need to Know!. JOURNAL OF PROTEOME RESEARCH, 21(12), 2837-2839. doi:10.1021/acs.jproteome.2c00704

DOI
10.1021/acs.jproteome.2c00704
Journal article

Exploring the conformational landscape and stability of Aurora A using ion-mobility mass spectrometry and molecular modelling

Tomlinson, L. J., Batchelor, M., Sarsby, J., Byrne, D. P., Brownridge, P., Bayliss, R., . . . Eyers, C. E. (2022). Exploring the conformational landscape and stability of Aurora A using ion-mobility mass spectrometry and molecular modelling. Journal of the American Society for Mass Spectrometry. doi:10.1021/jasms.1c00271

DOI
10.1021/jasms.1c00271
Journal article

2021

Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing’s syndrome

DOI
10.1101/2021.10.18.464848
Preprint

2020

Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics

Byrne, D. P., Clarke, C. J., Brownridge, P. J., Kalyuzhnyy, A., Perkins, S., Campbell, A., . . . Eyers, C. E. (2020). Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics. The Biochemical journal, 477(13), 2451-2475. doi:10.1042/bcj20200309

DOI
10.1042/bcj20200309
Journal article

Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signaling networks using SILAC-based phosphoproteomics

DOI
10.1101/2020.05.22.110767
Preprint

Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke Schistosoma mansoni Pinpoints Secreted Proteins for Vaccine Development.

Neves, L. X., Wilson, R. A., Brownridge, P., Harman, V. M., Holman, S. W., Beynon, R. J., . . . Castro-Borges, W. (2020). Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke <i>Schistosoma mansoni</i> Pinpoints Secreted Proteins for Vaccine Development. JOURNAL OF PROTEOME RESEARCH, 19(1), 314-326. doi:10.1021/acs.jproteome.9b00531

DOI
10.1021/acs.jproteome.9b00531
Journal article

High-Throughput Characterization of Histidine Phosphorylation Sites Using UPAX and Tandem Mass Spectrometry

Hardman, G., & Eyers, C. E. (2020). High-Throughput Characterization of Histidine Phosphorylation Sites Using UPAX and Tandem Mass Spectrometry. In HISTIDINE PHOSPHORYLATION (Vol. 2077, pp. 225-235). doi:10.1007/978-1-4939-9884-5_15

DOI
10.1007/978-1-4939-9884-5_15
Chapter

Histidine Phosphorylation Methods and Protocols Preface

Eyers, C. E. (2020). Histidine Phosphorylation Methods and Protocols Preface. In HISTIDINE PHOSPHORYLATION (Vol. 2077, pp. V). Retrieved from https://www.webofscience.com/

Chapter

2019

Myoblast Phosphoproteomics as a Tool to Investigate Global Signaling Events During Myogenesis.

Jones, F. K., Hardman, G. E., Ferries, S., Eyers, C. E., & Pisconti, A. (2019). Myoblast Phosphoproteomics as a Tool to Investigate Global Signaling Events During Myogenesis. MYOGENESIS, 2019 EDITION, 1889, 301-317. doi:10.1007/978-1-4939-8897-6_18

DOI
10.1007/978-1-4939-8897-6_18
Journal article

2018

Covalent Aurora A regulation by the metabolic integrator coenzyme A

DOI
10.1101/469585
Preprint

New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

Byrne, D. P., Li, Y., Ramakrishnan, K., Barsukov, I. L., Yates, E. A., Eyers, C. E., . . . Eyers, P. A. (2018). New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2417-2433. doi:10.1042/BCJ20180265

DOI
10.1042/BCJ20180265
Journal article

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

Byrne, D. P., Li, Y., Ngamlert, P., Ramakrishnan, K., Eyers, C. E., Wells, C., . . . Eyers, P. A. (2018). New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2435-2455. doi:10.1042/BCJ20180266

DOI
10.1042/BCJ20180266
Journal article

2017

2016

RePLiCal: A QconCAT Protein for Retention Time Standardization in Proteomics Studies

Holman, S. W., McLean, L., & Eyers, C. E. (2016). RePLiCal: A QconCAT Protein for Retention Time Standardization in Proteomics Studies. JOURNAL OF PROTEOME RESEARCH, 15(3), 1090-1102. doi:10.1021/acs.jproteome.5b00988

DOI
10.1021/acs.jproteome.5b00988
Journal article

2015

In honour of Professor Simon Gaskell's 65th birthday

Eyers, C. E., & Wysocki, V. H. (2015). In honour of Professor Simon Gaskell's 65th birthday. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 391, 1. doi:10.1016/j.ijms.2015.10.013

DOI
10.1016/j.ijms.2015.10.013
Journal article

Mass spectrometry for structural analysis and quantification of the Major Urinary Proteins of the house mouse

Beynon, R. J., Armstrong, S. D., Claydon, A. J., Davidson, A. J., Eyers, C. E., Langridge, J. I., . . . Woolerton, Y. E. (2015). Mass spectrometry for structural analysis and quantification of the Major Urinary Proteins of the house mouse. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 391, 146-156. doi:10.1016/j.ijms.2015.07.026

DOI
10.1016/j.ijms.2015.07.026
Journal article

Focus on Quantitative Proteomics

Lilley, K. S., Beynon, R. J., Eyers, C. E., & Hubbard, S. J. (2015). Focus on Quantitative Proteomics. PROTEOMICS, 15(18), 3101-3103. doi:10.1002/pmic.201570163

DOI
10.1002/pmic.201570163
Journal article

Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in <i>Saccharomyces cerevisiae</i>

Jamuczak, A. E., Eyers, C. E., Schwartz, J. -M., Grant, C. M., & Hubbard, S. J. (2015). Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in <i>Saccharomyces cerevisiae</i>. PROTEOMICS, 15(18), 3126-3139. doi:10.1002/pmic.201400527

DOI
10.1002/pmic.201400527
Journal article

Protein Structure

Barran, P., Cooper, H., & Eyers, C. (2015). Protein Structure. PROTEOMICS, 15(16), 2731-2732. doi:10.1002/pmic.201570143

DOI
10.1002/pmic.201570143
Journal article

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner

Bailey, F., Byrne, D., Oruganty, K., Eyers, C., Novotny, C. J., Shokat, K. M., . . . Eyers, P. (2015). The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner. Biochemical Journal, 467(1), 47-62. doi:10.1042/BJ20141441

DOI
10.1042/BJ20141441
Journal article

2014

Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling

Wang, X., Regufe da Mota, S., Rui, L., Moore, C. E., XIe, J., Lanucara, F., . . . Proud, C. G. (2014). Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling. Molecular and Cellular Biology, 34(22), 4088-4103. doi:10.1128/MCB.01035-14

DOI
10.1128/MCB.01035-14
Journal article

Probing the exposure of the phosphate group in modified amino acids and peptides by ion-molecule reactions with triethoxyborane in Fourier transform ion cyclotron resonance mass spectrometry

Lanucara, F., Fornarini, S., Eyers, C. E., & Crestoni, M. E. (2014). Probing the exposure of the phosphate group in modified amino acids and peptides by ion-molecule reactions with triethoxyborane in Fourier transform ion cyclotron resonance mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 28(10), 1107-1116. doi:10.1002/rcm.6884

DOI
10.1002/rcm.6884
Journal article

Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing (vol 6, pg 65, 2014)

Both, P., Green, A. P., Gray, C. J., Sardzik, R., Voglmeir, J., Fontana, C., . . . Eyers, C. E. (2014). Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing (vol 6, pg 65, 2014). NATURE CHEMISTRY, 6(4), 368. doi:10.1038/NCHEM.1901

DOI
10.1038/NCHEM.1901
Journal article

Quantitative Proteomics

Quantitative Proteomics (2014). (Vol. 1). doi:10.1039/9781782626985

DOI
10.1039/9781782626985
Book

Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing

Both, P., Green, A. P., Gray, C. J., Sardzik, R., Voglmeir, J., Fontana, C., . . . Eyers, C. E. (2014). Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing. NATURE CHEMISTRY, 6(1), 65-74. doi:10.1038/NCHEM.1817

DOI
10.1038/NCHEM.1817
Journal article

Quantitative Proteomics Preface

Eyers, C. E. (2014). Quantitative Proteomics Preface. In QUANTITATIVE PROTEOMICS (Vol. 1, pp. V-VII). Retrieved from https://www.webofscience.com/

Chapter

2013

ChemInform Abstract: Enzymatic Reactions on Immobilized Substrates

Gray, C. J., Weissenborn, M. J., Eyers, C. E., & Flitsch, S. L. (2013). ChemInform Abstract: Enzymatic Reactions on Immobilized Substrates. ChemInform, 44(40). doi:10.1002/chin.201340262

DOI
10.1002/chin.201340262
Journal article

Enzymatic reactions on immobilised substrates

Gray, C. J., Weissenborn, M. J., Eyers, C. E., & Flitsch, S. L. (2013). Enzymatic reactions on immobilised substrates. CHEMICAL SOCIETY REVIEWS, 42(15), 6378-6405. doi:10.1039/c3cs60018a

DOI
10.1039/c3cs60018a
Journal article

Attempting to rewrite <i>History</i>: challenges with the analysis of histidine-phosphorylated peptides

Gonzalez-Sanchez, M. -B., Lanucara, F., Helm, M., & Eyers, C. E. (2013). Attempting to rewrite <i>History</i>: challenges with the analysis of histidine-phosphorylated peptides. BIOCHEMICAL SOCIETY TRANSACTIONS, 41, 1089-1095. doi:10.1042/BST20130072

DOI
10.1042/BST20130072
Journal article

The nitrosated bile acid DNA lesion <i>O</i><SUP>6</SUP>-carboxymethylguanine is a substrate for the human DNA repair protein <i>O</i><SUP>6</SUP>-methylguanine-DNA methyltransferase

Senthong, P., Millington, C. L., Wilkinson, O. J., Marriott, A. S., Watson, A. J., Reamtong, O., . . . Povey, A. C. (2013). The nitrosated bile acid DNA lesion <i>O</i><SUP>6</SUP>-carboxymethylguanine is a substrate for the human DNA repair protein <i>O</i><SUP>6</SUP>-methylguanine-DNA methyltransferase. NUCLEIC ACIDS RESEARCH, 41(5), 3047-3055. doi:10.1093/nar/gks1476

DOI
10.1093/nar/gks1476
Journal article

A novel approach to the analysis of SUMOylation with the independent use of trypsin and elastase digestion followed by database searching utilising consecutive residue addition to lysine

Chicooree, N., Griffiths, J. R., Connolly, Y., Tan, C. -T., Malliri, A., Eyers, C. E., & Smith, D. L. (2013). A novel approach to the analysis of SUMOylation with the independent use of trypsin and elastase digestion followed by database searching utilising consecutive residue addition to lysine. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 27(1), 127-134. doi:10.1002/rcm.6425

DOI
10.1002/rcm.6425
Journal article

CoPY - Census of the Proteome of Yeast: Quantification of the <i>S</i>. <i>cerevisiae</i> proteome

Lanthaler, K., Holman, S., Lawless, C., Watkins, R., Brownridge, P., Harman, V., . . . Beynon, R. (2013). CoPY - Census of the Proteome of Yeast: Quantification of the <i>S</i>. <i>cerevisiae</i> proteome. In YEAST Vol. 30 (pp. 188). Retrieved from https://www.webofscience.com/

Conference Paper

Top-down mass spectrometry for the analysis of combinatorial post-translational modifications

Lanucara, F., & Eyers, C. E. (2013). Top-down mass spectrometry for the analysis of combinatorial post-translational modifications. MASS SPECTROMETRY REVIEWS, 32(1), 27-42. doi:10.1002/mas.21348

DOI
10.1002/mas.21348
Journal article

2012

Dual purpose <i>S</i>-trityl-linkers for glycoarray fabrication on both polystyrene and gold

Wehner, J. W., Weissenborn, M. J., Hartmann, M., Gray, C. J., Sardzik, R., Eyers, C. E., . . . Lindhorst, T. K. (2012). Dual purpose <i>S</i>-trityl-linkers for glycoarray fabrication on both polystyrene and gold. ORGANIC & BIOMOLECULAR CHEMISTRY, 10(44), 8919-8926. doi:10.1039/c2ob26118a

DOI
10.1039/c2ob26118a
Journal article

QconCAT Standard for Calibration of Ion Mobility-Mass Spectrometry Systems

Chawner, R., McCullough, B., Giles, K., Barran, P. E., Gaskell, S. J., & Eyers, C. E. (2012). QconCAT Standard for Calibration of Ion Mobility-Mass Spectrometry Systems. JOURNAL OF PROTEOME RESEARCH, 11(11), 5564-5572. doi:10.1021/pr3005327

DOI
10.1021/pr3005327
Journal article

The N-Methylated Peptide SEN304 Powerfully Inhibits Aβ(1-42) Toxicity by Perturbing Oligomer Formation

Amijee, H., Bate, C., Williams, A., Virdee, J., Jeggo, R., Spanswick, D., . . . Doig, A. J. (2012). The N-Methylated Peptide SEN304 Powerfully Inhibits Aβ(1-42) Toxicity by Perturbing Oligomer Formation. BIOCHEMISTRY, 51(42), 8338-8352. doi:10.1021/bi300415v

DOI
10.1021/bi300415v
Journal article

The use of selected reaction monitoring in quantitative proteomics

Holman, S. W., Sims, P. F. G., & Eyers, C. E. (2012). The use of selected reaction monitoring in quantitative proteomics. BIOANALYSIS, 4(14), 1763-1786. doi:10.4155/BIO.12.126

DOI
10.4155/BIO.12.126
Journal article

The influence of a C-terminal basic residue on peptide fragmentation pathways

Chawner, R., Eyers, C. E., & Gaskell, S. J. (2012). The influence of a C-terminal basic residue on peptide fragmentation pathways. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 316, 284-291. doi:10.1016/j.ijms.2012.02.017

DOI
10.1016/j.ijms.2012.02.017
Journal article

Proposal for a common nomenclature for peptide fragment ions generated following sequence scrambling during collision-induced dissociation

Chawner, R., Gaskell, S. J., & Eyers, C. E. (2012). Proposal for a common nomenclature for peptide fragment ions generated following sequence scrambling during collision-induced dissociation. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 26(2), 205-206. doi:10.1002/rcm.5294

DOI
10.1002/rcm.5294
Journal article

The Nitrosated Bile Acid DNA Lesion, <i>O</i><SUP>6</SUP>-carboxymethylguanine, Is a Substrate for Human <i>O</i><SUP>6</SUP>-alkylguanine DNA Alkyltransferase

Senthong, P., Williams, D. M., Wilkinson, O., Millington, C., Marriott, A., Watson, A. J., . . . Povey, A. C. (2012). The Nitrosated Bile Acid DNA Lesion, <i>O</i><SUP>6</SUP>-carboxymethylguanine, Is a Substrate for Human <i>O</i><SUP>6</SUP>-alkylguanine DNA Alkyltransferase. In ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 53 (pp. S36). Retrieved from https://www.webofscience.com/

Conference Paper

2011

Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH

Carroll, K. M., Simpson, D. M., Eyers, C. E., Knight, C. G., Brownridge, P., Dunn, W. B., . . . Beynon, R. J. (2011). Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH. MOLECULAR & CELLULAR PROTEOMICS, 10(12). doi:10.1074/mcp.M111.007633

DOI
10.1074/mcp.M111.007633
Journal article

CONSeQuence: Prediction of Reference Peptides for Absolute Quantitative Proteomics Using Consensus Machine Learning Approaches

Eyers, C. E., Lawless, C., Wedge, D. C., Lau, K. W., Gaskell, S. J., & Hubbard, S. J. (2011). CONSeQuence: Prediction of Reference Peptides for Absolute Quantitative Proteomics Using Consensus Machine Learning Approaches. MOLECULAR & CELLULAR PROTEOMICS, 10(11). doi:10.1074/mcp.M110.003384

DOI
10.1074/mcp.M110.003384
Journal article

Identification of a Lacosamide Binding Protein Using an Affinity Bait and Chemical Reporter Strategy: 14-3-3 ζ

Park, K. D., Kim, D., Reamtong, O., Eyers, C., Gaskell, S. J., Liu, R., & Kohn, H. (2011). Identification of a Lacosamide Binding Protein Using an Affinity Bait and Chemical Reporter Strategy: 14-3-3 ζ. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(29), 11320-11330. doi:10.1021/ja2034156

DOI
10.1021/ja2034156
Journal article

MASS SPECTROMETRIC-BASED QUANTITATIVE PROTEOMICS USING SILAC

Lanucara, F., & Eyers, C. E. (2011). MASS SPECTROMETRIC-BASED QUANTITATIVE PROTEOMICS USING SILAC. METHODS IN ENZYMOLOGY, VOL 500, 500, 133-150. doi:10.1016/B978-0-12-385118-5.00008-6

DOI
10.1016/B978-0-12-385118-5.00008-6
Journal article

QUANTIFICATION OF PROTEINS AND THEIR MODIFICATIONS USING QCONCAT TECHNOLOGY

Carroll, K. M., Lanucara, F., & Eyers, C. E. (2011). QUANTIFICATION OF PROTEINS AND THEIR MODIFICATIONS USING QCONCAT TECHNOLOGY. METHODS IN ENZYMOLOGY, VOL 500, 500, 113-131. doi:10.1016/B978-0-12-385118-5.00007-4

DOI
10.1016/B978-0-12-385118-5.00007-4
Journal article

2010

Analysis of Post-translational Modifications by LC-MS/MS

Johnson, H., & Eyers, C. E. (2010). Analysis of Post-translational Modifications by LC-MS/MS. LC-MS/MS IN PROTEOMICS: METHODS AND APPLICATIONS, 658, 93-108. doi:10.1007/978-1-60761-780-8_5

DOI
10.1007/978-1-60761-780-8_5
Journal article

2009

Rigorous determination of the stoichiometry of protein phosphorylation using mass spectrometry

Johnson, H., Eyers, C. E., Eyers, P. A., Beynon, R. J., & Gaskell, S. J. (2009). Rigorous determination of the stoichiometry of protein phosphorylation using mass spectrometry. Journal of the American Society for Mass Spectrometry, 20(12), 2211-2220. doi:10.1016/j.jasms.2009.08.009

DOI
10.1016/j.jasms.2009.08.009
Journal article

2008

QCAL—a novel standard for assessing instrument conditions for proteome analysis

Eyers, C., Simpson, D. M., Wong, C. C. S., Beynon, R. J., & Gaskell, S. J. (2008). QCAL—a novel standard for assessing instrument conditions for proteome analysis. Journal of the American Society for Mass Spectrometry, 19(9), 1275-1280. doi:10.1016/j.jasms.2008.05.019

DOI
10.1016/j.jasms.2008.05.019
Journal article

Mass Spectrometry to Identify Posttranslational Modifications

Eyers, C. E., & Gaskell, S. J. (n.d.). Mass Spectrometry to Identify Posttranslational Modifications. Unknown Journal, 1-34. doi:10.1002/9780470048672.wecb469

DOI
10.1002/9780470048672.wecb469
Journal article

2007

Peptide Detectability following ESI Mass Spectrometry: Prediction using Genetic Programming

Wedge, D. C., Kell, D. B., Gaskell, S. J., Lau, K. W., Hubbard, S. J., & Eyers, C. (2007). Peptide Detectability following ESI Mass Spectrometry: Prediction using Genetic Programming. In GECCO 2007: GENETIC AND EVOLUTIONARY COMPUTATION CONFERENCE, VOL 1 AND 2 (pp. 2219-+). Retrieved from https://www.webofscience.com/

Conference Paper

Proteomic analysis of the adaptation of the host NSO myeloma cell line to a protein-free medium

De La Luz-Hernández, K. R., Rojas-Del Calvo, L., Victores-Sarasola, S., Lage-Castellanos, A., Eyers, C., Hart, S., . . . Gaskell, S. (2007). Proteomic analysis of the adaptation of the host NSO myeloma cell line to a protein-free medium. Biotecnologia Aplicada, 24(3-4), 215-223.

Journal article

2005

The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ

Eyers, C. E., McNeill, H., Knebel, A., Morrice, N., Arthur, S. J. C., Cuenda, A., & Cohen, P. (2005). The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ. BIOCHEMICAL JOURNAL, 389, 127-135. doi:10.1042/BJ20050387

DOI
10.1042/BJ20050387
Journal article

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Fraga, M. F., Ballestar, E., Villar-Garea, A., Boix-Chornet, M., Espada, J., Schotta, G., . . . Esteller, M. (2005). Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. NATURE GENETICS, 37(4), 391-400. doi:10.1038/ng1531

DOI
10.1038/ng1531
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2003

The characterization of protein post-translational modifications by mass spectrometry

Schweppe, R. E., Haydon, C. E., Lewis, T. S., Resing, K. A., & Ahn, N. G. (2003). The characterization of protein post-translational modifications by mass spectrometry. ACCOUNTS OF CHEMICAL RESEARCH, 36(6), 453-461. doi:10.1021/ar020143l

DOI
10.1021/ar020143l
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Identification of novel phosphorylation sites on <i>Xenopus laevis</i> aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography

Haydon, C. E., Eyers, P. A., Aveline-Wolf, L. D., Resing, K. A., Maller, J. L., & Ahn, N. G. (2003). Identification of novel phosphorylation sites on <i>Xenopus laevis</i> aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography. MOLECULAR & CELLULAR PROTEOMICS, 2(10), 1055-1067. doi:10.1074/mcp.M300054-MCP200

DOI
10.1074/mcp.M300054-MCP200
Journal article

2002

Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways

Knebel, A., Haydon, C. E., Morrice, N., & Cohen, P. (2002). Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways. BIOCHEMICAL JOURNAL, 367, 525-532. doi:10.1042/BJ20020916

DOI
10.1042/BJ20020916
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Identification of a phosphorylation site on skeletal muscle myosin light chain kinase that becomes phosphorylated during muscle contraction

Haydon, C. E., Watt, P. W., Morrice, N., Knebel, A., Gaestel, M., & Cohen, P. (2002). Identification of a phosphorylation site on skeletal muscle myosin light chain kinase that becomes phosphorylated during muscle contraction. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 397(2), 224-231. doi:10.1006/abbi.2001.2625

DOI
10.1006/abbi.2001.2625
Journal article