Publications
Selected publications
- Susceptibility of OXA-48-like-producing Enterobacterales to flomoxef. (Journal article - 2024)
- Molecular pharmacodynamics of meropenem for nosocomial pneumonia caused by <i>Pseudomonas aeruginosa</i>. (Journal article - 2024)
2024
Reevaluating Piperacillin-Tazobactam Mortality.
Darlow, C. A., Gerada, A., & Hope, W. (2024). Reevaluating Piperacillin-Tazobactam Mortality.. JAMA internal medicine, 184(10), 1267-1268. doi:10.1001/jamainternmed.2024.4114
Susceptibility of OXA-48-like-producing Enterobacterales to flomoxef.
Owen, V., Harper, N., Dubey, V., Gerada, A., Boyd, S. E., & Darlow, C. A. (2024). Susceptibility of OXA-48-like-producing Enterobacterales to flomoxef.. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, S1198-743X(24)00346-X. doi:10.1016/j.cmi.2024.07.017
Molecular pharmacodynamics of meropenem for nosocomial pneumonia caused by <i>Pseudomonas aeruginosa</i>.
Farrington, N., Dubey, V., Johnson, A., Horner, I., Stevenson, A., Unsworth, J., . . . Darlow, C. A. (2024). Molecular pharmacodynamics of meropenem for nosocomial pneumonia caused by <i>Pseudomonas aeruginosa</i>.. mBio, 15(2), e0316523. doi:10.1128/mbio.03165-23
2023
26 Fulminant primary EBV infection – Manifestations and complications in a host requiring ECMO
Hey, S., Haigh, D., Darlow, C., Barrera, M., & Garcia, M. (2023). 26 Fulminant primary EBV infection – Manifestations and complications in a host requiring ECMO. Clinical Infection in Practice, 20, 100291. doi:10.1016/j.clinpr.2023.100291
Development and application of neonatal physiology-based pharmacokinetic models of amikacin and fosfomycin to assess pharmacodynamic target attainment.
Darlow, C. A., Parrott, N., Peck, R. W., & Hope, W. (2023). Development and application of neonatal physiology-based pharmacokinetic models of amikacin and fosfomycin to assess pharmacodynamic target attainment.. CPT: pharmacometrics & systems pharmacology. doi:10.1002/psp4.13097
2022
Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings
Darlow, C. A., McEntee, L., Johnson, A., Farrington, N., Unsworth, J., Jimenez-Valverde, A., . . . Hope, W. (2022). Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(12), 3349-3357. doi:10.1093/jac/dkac323
30 Determining a potential alternative empirical antibiotic regimen for the treatment of neonatal sepsis in low- and middle-income settings using pre-clinical in vitro techniques
Darlow, C., Farrington, N., McEntee, L., Johnson, A., Unsworth, J., Jimenez-Valverde, A., . . . Hope, W. (2022). 30 Determining a potential alternative empirical antibiotic regimen for the treatment of neonatal sepsis in low- and middle-income settings using pre-clinical in vitro techniques. Clinical Infection in Practice, 15, 100191. doi:10.1016/j.clinpr.2022.100191
Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales (vol 77, pg 711, 2022)
Darlow, C. A., & Hope, W. (2022). Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales (vol 77, pg 711, 2022). JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(7), 2049. doi:10.1093/jac/dkac153
Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales-authors' response
Darlow, C. A., & Hope, W. (2022). Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales-authors' response. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(7), 2047-2048. doi:10.1093/jac/dkac072
Determining an Alternate Antimicrobial Regimen for the Empiric Treatment of Neonatal Sepsis in Low- and Middle-Income Countries in the Context of Rising Antimicrobial Resistance
Darlow, C. (2022, June 6). Determining an Alternate Antimicrobial Regimen for the Empiric Treatment of Neonatal Sepsis in Low- and Middle-Income Countries in the Context of Rising Antimicrobial Resistance.
Flomoxef and fosfomycin in combination for the treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance
Darlow, C. A., Farrington, N., Johnson, A., McEntee, L., Unsworth, J., Jimenez-Valverde, A., . . . Hope, W. (2022). Flomoxef and fosfomycin in combination for the treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(5), 1334-1343. doi:10.1093/jac/dkac038
Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance
Farrington, N., McEntee, L., Johnson, A., Unsworth, J., Darlow, C., Jimenez-Valverde, A., . . . Hope, W. (2022). Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 66(4). doi:10.1128/aac.02181-21
2021
Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales
Darlow, C. A., & Hope, W. (2021). Flomoxef for neonates: extending options for treatment of neonatal sepsis caused by ESBL-producing Enterobacterales. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(3), 711-718. doi:10.1093/jac/dkab468
Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial (vol 68, pg S67, 2019)
Theiss-Nyland, K., Shakya, M., Colin-Jones, R., Voysey, M., Smith, N., Karkey, A., . . . Pollard, A. J. (2021). Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infections Among Nepalese Children: A Protocol for a Phase III, Randomized Control Trial (vol 68, pg S67, 2019). CLINICAL INFECTIOUS DISEASES, 73(10), 1950. doi:10.1093/cid/ciab802
Potential Antibiotics for the Treatment of Neonatal Sepsis Caused by Multidrug-Resistant Bacteria
Darlow, C. A., da Costa, R. M. A., Ellis, S., Franceschi, F., Sharland, M., Piddock, L., . . . Hope, W. (2021). Potential Antibiotics for the Treatment of Neonatal Sepsis Caused by Multidrug-Resistant Bacteria. PEDIATRIC DRUGS, 23(5), 465-484. doi:10.1007/s40272-021-00465-z
Application of the hollow fibre infection model (HFIM) in antimicrobial development: a systematic review and recommendations of reporting
Sadouki, Z., McHugh, T. D., Aarnoutse, R., Canseco, J. O., Darlow, C., Hope, W., . . . Kloprogge, F. (2021). Application of the hollow fibre infection model (HFIM) in antimicrobial development: a systematic review and recommendations of reporting. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 76(9), 2252-2259. doi:10.1093/jac/dkab160
Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.
Darlow, C. A., Docobo-Perez, F., Farrington, N., Johnson, A., McEntee, L., Unsworth, J., . . . Hope, W. (2021). Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.. Antimicrobial Agents and Chemotherapy. doi:10.1128/aac.00293-21
2020
Microbial aetiology of brain abscess in a UK cohort: Prominent role of Streptococcus intermedius
Darlow, C. A., McGlashan, N., Kerr, R., Oakley, S., Pretorius, P., Jones, N., & Matthews, P. C. (2020). Microbial aetiology of brain abscess in a UK cohort: Prominent role of Streptococcus intermedius. JOURNAL OF INFECTION, 80(6), 623-629. doi:10.1016/j.jinf.2020.03.011
2019
Factors influencing participation in controlled human infection models: a pooled analysis from six enteric fever studies
Oguti, B., Gibani, M., Darlow, C., Waddington, C. S., Jin, C., Plested, E., . . . Pollard, A. J. (n.d.). Factors influencing participation in controlled human infection models: a pooled analysis from six enteric fever studies. Wellcome Open Research, 4, 153. doi:10.12688/wellcomeopenres.15469.1
Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model
Gibani, M. M., Jones, E., Barton, A., Jin, C., Meek, J., Camara, S., . . . Pollard, A. J. (2019). Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model. NATURE MEDICINE, 25(7), 1082-+. doi:10.1038/s41591-019-0505-4
2017
A spinal infection with <i>Staphylococcus pseudintermedius</i>.
Darlow, C. A., Paidakakos, N., Sikander, M., & Atkins, B. (2017). A spinal infection with <i>Staphylococcus pseudintermedius</i>.. BMJ case reports, 2017, bcr-2017-221260. doi:10.1136/bcr-2017-221260
2013
Remembering the Children: Implementation and Success of a Robust Method for Identifying and Testing Children of HIV Patients.
Darlow, C., Tovey, P., Wallis, F., Knowles, C., Fairley, I., Lacey, C., & Martin, F. (2013). Remembering the Children: Implementation and Success of a Robust Method for Identifying and Testing Children of HIV Patients.. Journal of sexually transmitted diseases, 2013, 828024. doi:10.1155/2013/828024
Remembering the children: Implementation and success of a robust method for the identification and testing of children of HIV-positive parents
Darlow, C., Wallis, F., Tovey, P., Knowles, C., Fairley, I., Lacey, C., & Martin, F. (2013). Remembering the children: Implementation and success of a robust method for the identification and testing of children of HIV-positive parents. In HIV MEDICINE Vol. 14 (pp. 32). Retrieved from https://www.webofscience.com/
2011
THE EFFECT OF CORTICOSTEROIDS ON THE T2 APPEARANCE OF GLIOBLASTOMA MULTIFORME
Darlow, C. A., Chapman, S., Mohsen, L. A., & Price, S. J. (2011). THE EFFECT OF CORTICOSTEROIDS ON THE T2 APPEARANCE OF GLIOBLASTOMA MULTIFORME. In NEURO-ONCOLOGY Vol. 13 (pp. 3). Retrieved from https://www.webofscience.com/