Publications
2024
Pyro(phospho)mania.
Eyers, C. E., & Clarke, C. J. (2024). Pyro(phospho)mania.. Nature chemical biology, 20(10), 1248-1249. doi:10.1038/s41589-024-01606-4
2023
Considerations for defining+80 Da mass shifts in mass spectrometry-based proteomics: phosphorylation and beyond
Daly, L. A., Clarke, C. J., Po, A., Oswald, S. O., & Eyers, C. E. (2023). Considerations for defining+80 Da mass shifts in mass spectrometry-based proteomics: phosphorylation and beyond. CHEMICAL COMMUNICATIONS, 59(77), 11484-11499. doi:10.1039/d3cc02909c
2020
Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics
Byrne, D. P., Clarke, C. J., Brownridge, P. J., Kalyuzhnyy, A., Perkins, S., Campbell, A., . . . Eyers, C. E. (2020). Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics. The Biochemical journal, 477(13), 2451-2475. doi:10.1042/bcj20200309
2019
Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation
Hardman, G., Perkins, S., Brownridge, P., Clarke, C., Byrne, D., Campbell, A., . . . Eyers, C. (2019). Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation. The EMBO Journal, 38(21). doi:10.15252/embj.2018100847
2017
Activation of tissue plasminogen activator by metastasis-inducing S100P protein
Clarke, C. J., Gross, S. R., Ismail, T. M., Rudland, P. S., Al-Medhtiy, M., Santangeli, M., & Barraclough, R. (2017). Activation of tissue plasminogen activator by metastasis-inducing S100P protein. BIOCHEMICAL JOURNAL, 474, 3227-3240. doi:10.1042/BCJ20170578
2016
Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation
Arecco, N., Clarke, C. J., Jones, F. K., Simpson, D. M., Mason, D., Beynon, R. J., & Pisconti, A. (2016). Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation. SCIENTIFIC REPORTS, 6. doi:10.1038/srep24708
2015
The metastasis-inducing protein AGR2 is <i>O</i>-glycosylated upon secretion from mammary epithelial cells
Clarke, C., Rudland, P., & Barraclough, R. (2015). The metastasis-inducing protein AGR2 is <i>O</i>-glycosylated upon secretion from mammary epithelial cells. MOLECULAR AND CELLULAR BIOCHEMISTRY, 408(1-2), 245-252. doi:10.1007/s11010-015-2502-3
2013
Metastasis-Promoting Anterior Gradient 2 Protein Has a Dimeric Thioredoxin Fold Structure and a Role in Cell Adhesion
Patel, P., Clarke, C., Barraclough, D. L., Jowitt, T. A., Rudland, P. S., Barraclough, R., & Lian, L. -Y. (2013). Metastasis-Promoting Anterior Gradient 2 Protein Has a Dimeric Thioredoxin Fold Structure and a Role in Cell Adhesion. JOURNAL OF MOLECULAR BIOLOGY, 425(5), 929-943. doi:10.1016/j.jmb.2012.12.009
Undated
Characterising the role of anterior gradient protein 2 in cell adhesion and metastasis
Clarke, C. (n.d.). Characterising the role of anterior gradient protein 2 in cell adhesion and metastasis. (PhD Thesis, University of Liverpool).