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Dr Christopher Cheyne
Ph.D.

Contact

C.P.Cheyne@liverpool.ac.uk

+44 (0)151 794 9717

Publications

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2024

Can self-testing be enhanced to hasten safe return of healthcare workers in pandemics? Random order, open label trial using two manufacturers’ SARS-CoV-2 lateral flow devices concurrently

DOI
10.21203/rs.3.rs-4483986/v1
Preprint

COVID-19 risk-mitigation in reopening mass cultural events: population-based observational study for the UK Events Research Programme in Liverpool City Region

Burnside, G., Cheyne, C. P., Leeming, G., Humann, M., Darby, A., Green, M. A., . . . Buchan, I. E. (2024). COVID-19 risk-mitigation in reopening mass cultural events: population-based observational study for the UK Events Research Programme in Liverpool City Region. Journal of the Royal Society of Medicine. doi:10.1177/01410768231182389

DOI
10.1177/01410768231182389
Journal article

2023

Association of SARS-CoV-2 viral load distributions with individual demographics and suspected variant type: Results from the Liverpool Community Testing Pilot - England, 6 November 2020‒8 September 2021

Hughes, D., Cheyne, C., Ashton, M., Coffee, E., Crozier, A., Semple, M., . . . Garcia-Finana, M. (n.d.). Association of SARS-CoV-2 viral load distributions with individual demographics and suspected variant type: Results from the Liverpool Community Testing Pilot - England, 6 November 2020‒8 September 2021. Eurosurveillance. doi:10.2807/1560-7917.ES.2023.28.4.2200129

DOI
10.2807/1560-7917.ES.2023.28.4.2200129
Journal article

2022

Changing patterns of SARS-CoV-2 infection through Delta and Omicron waves by vaccination status, previous infection and neighbourhood deprivation: a cohort analysis of 2.7 M people

Green, M. A., Hungerford, D. J., Hughes, D. M., Garcia-Finana, M., Turtle, L., Cheyne, C., . . . Buchan, I. (2022). Changing patterns of SARS-CoV-2 infection through Delta and Omicron waves by vaccination status, previous infection and neighbourhood deprivation: a cohort analysis of 2.7 M people. BMC INFECTIOUS DISEASES, 22(1). doi:10.1186/s12879-022-07878-2

DOI
10.1186/s12879-022-07878-2
Journal article

Phase I/II Clinical Trials of Donor-Derived Purified Regulatory T Cells for the Treatment of Steroid-Refractory Chronic Graft Versus Host Disease

Soares, M. V., Gomez, V. E., Azevedo, R. I., Pereira, P. N. G., Velazquez, T. C., Garcia-Calderon, C. B., . . . Lacerda, J. F. (2022). Phase I/II Clinical Trials of Donor-Derived Purified Regulatory T Cells for the Treatment of Steroid-Refractory Chronic Graft Versus Host Disease. In BLOOD Vol. 140. doi:10.1182/blood-2022-163394

DOI
10.1182/blood-2022-163394
Conference Paper

Daily testing of contacts of SARS-CoV-2 infected cases as an alternative to quarantine for key workers in Liverpool: A prospective cohort study

Marsden, L., Hughes, D. M., Corcoran, R., Cheyne, C. P., Ashton, M., Buchan, I., . . . Garcia-Finana, M. (2022). Daily testing of contacts of SARS-CoV-2 infected cases as an alternative to quarantine for key workers in Liverpool: A prospective cohort study. ECLINICALMEDICINE, 50. doi:10.1016/j.eclinm.2022.101519

DOI
10.1016/j.eclinm.2022.101519
Journal article

Effectiveness of the BNT162b2 (Pfizer-BioNTech) and the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccines for reducing susceptibility to infection with the Delta variant (B.1.617.2) of SARS-CoV-2

Pattni, K., Hungerford, D., Adams, S., Buchan, I., Cheyne, C. P., García-Fiñana, M., . . . Sharkey, K. J. (n.d.). Effectiveness of the BNT162b2 (Pfizer-BioNTech) and the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccines for reducing susceptibility to infection with the Delta variant (B.1.617.2) of SARS-CoV-2. BMC Infectious Diseases, 22(1). doi:10.1186/s12879-022-07239-z

DOI
10.1186/s12879-022-07239-z
Journal article

2021

Performance of the Innova SARS-CoV-2 antigen rapid lateral flow test in the Liverpool asymptomatic testing pilot: population based cohort study

Garcia-Finana, M., Hughes, D. M., Cheyne, C. P., Burnside, G., Stockbridge, M., Fowler, T. A., . . . Buchan, I. (2021). Performance of the Innova SARS-CoV-2 antigen rapid lateral flow test in the Liverpool asymptomatic testing pilot: population based cohort study. BMJ-BRITISH MEDICAL JOURNAL, 374. doi:10.1136/bmj.n1637

DOI
10.1136/bmj.n1637
Journal article

Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

Docherty, A., Mulholland, R., Lone, N. I., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . Semple, M. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 773-785. doi:10.1016/S2213-2600(21)00175-2

DOI
10.1016/S2213-2600(21)00175-2
Journal article

Evaluating social and spatial inequalities of large scale rapid lateral flow SARS-CoV-2 antigen testing in COVID-19 management: An observational study of Liverpool, UK (November 2020 to January 2021)

Green, M. A., Garcia-Finana, M., Barr, B., Burnside, G., Cheyne, C. P., Hughes, D., . . . Buchan, I. E. (2021). Evaluating social and spatial inequalities of large scale rapid lateral flow SARS-CoV-2 antigen testing in COVID-19 management: An observational study of Liverpool, UK (November 2020 to January 2021). LANCET REGIONAL HEALTH-EUROPE, 6. doi:10.1016/j.lanepe.2021.100107

DOI
10.1016/j.lanepe.2021.100107
Journal article

Evaluating Social and Spatial Inequalities of Large Scale Rapid Lateral Flow SARS-CoV-2 Antigen Testing in COVID-19 Management: An Observational Study of Liverpool, UK (November 2020 to January 2021)

Green, M., Garcia-Finana, M., Barr, B., Burnside, G., Cheyne, C., Hughes, D., . . . Buchan, I. (2021). Evaluating Social and Spatial Inequalities of Large Scale Rapid Lateral Flow SARS-CoV-2 Antigen Testing in COVID-19 Management: An Observational Study of Liverpool, UK (November 2020 to January 2021). doi:10.2139/ssrn.3786003

DOI
10.2139/ssrn.3786003
Journal article

Safety and cost-effectiveness of individualised screening for diabetic retinopathy: the ISDR open-label, equivalence RCT

Broadbent, D., Wang, A., Cheyne, C., James, M., Lathe, J., Stratton, I., . . . Harding, S. (2021). Safety and cost-effectiveness of individualised screening for diabetic retinopathy: the ISDR open-label, equivalence RCT. Diabetologia, 64(1), 56-69. doi:10.1007/s00125-020-05313-2

DOI
10.1007/s00125-020-05313-2
Journal article

2020

Changes in UK hospital mortality in the first wave of COVID-19: the ISARIC WHO Clinical Characterisation Protocol prospective multicentre observational cohort study

Docherty, A., Mulholland, R., Lone, N., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . for ISARIC4C investigators. (2020). Changes in UK hospital mortality in the first wave of COVID-19: the ISARIC WHO Clinical Characterisation Protocol prospective multicentre observational cohort study. doi:10.1101/2020.12.19.20248559

DOI
10.1101/2020.12.19.20248559
Journal article

2019

Methodological aspects of the ISDR RCT: Investigating individualised variable interval screening for diabetic retinopathy in a screening population

Cheyne, C. P., Broadbent, D. M., Moitt, T., Howard, L., Howlin, S., Silvera, K., . . . Garcia-Finana, M. (2019). Methodological aspects of the ISDR RCT: Investigating individualised variable interval screening for diabetic retinopathy in a screening population. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/

Poster

Individualised screening for diabetic retinopathy: the ISDR study - rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening

Broadbent, D. M., Sampson, C. J., Wang, A., Howard, L., Williams, A. E., Howlin, S. U., . . . Harding, S. P. (2019). Individualised screening for diabetic retinopathy: the ISDR study - rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening. BMJ OPEN, 9(6). doi:10.1136/bmjopen-2018-025788

DOI
10.1136/bmjopen-2018-025788
Journal article

2017

Individualised variable interval risk-based screening for sight threatening diabetic retinopathy – the Liverpool Risk Calculation Engine

Harding, S. P., Eleuteri, A., Fisher, A. C., Broadbent, D. M., Garcia-Finana, M., Cheyne, C. P., . . . Seddon, D. (2017). Individualised variable interval risk-based screening for sight threatening diabetic retinopathy – the Liverpool Risk Calculation Engine. Diabetologia, 60(11), 2174-2182. doi:10.1007/s00125-017-4386-0

DOI
10.1007/s00125-017-4386-0
Journal article

A novel multivariate discriminant approach to predict sight threatening diabetic retinopathy (STDR) cases - data from the Liverpool Diabetic Eye Study

Garcia-Finana, M., Hughes, D. M., Cheyne, C. P., Broadbent, D. M., Wang, A., Mobayen-Rahni, M., . . . Harding, S. P. (2017). A novel multivariate discriminant approach to predict sight threatening diabetic retinopathy (STDR) cases - data from the Liverpool Diabetic Eye Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/

Conference Paper

SAFETY OF INDIVIDUALISED VARIABLE INTERVAL SCREENING FOR REFERABLE DIABETIC RETINOPATHY: BASELINE DATA FROM THE ISDR RANDOMISED CONTROLLED STUDY

Harding, S. P., Cheyne, C. P., Broadbent, D. M., Appelbe, D., Wang, A., Rahni, M., . . . Finana, M. G. (2017). SAFETY OF INDIVIDUALISED VARIABLE INTERVAL SCREENING FOR REFERABLE DIABETIC RETINOPATHY: BASELINE DATA FROM THE ISDR RANDOMISED CONTROLLED STUDY. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 27 (pp. E126). Retrieved from https://www.webofscience.com/

Conference Paper

2016

Cognition in school-age children exposed to levetiracetam, topiramate, or sodium valproate

Bromley, R., Calderbank, R., Cheyne, C. P., Rooney, C., Trayner, P., Cohen., . . . Baker, G. A. (2016). Cognition in school-age children exposed to levetiracetam, topiramate, or sodium valproate. Neurology, 87(18). doi:10.1212/WNL.0000000000003157

DOI
10.1212/WNL.0000000000003157
Journal article

Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research

Hughes., Czanner, G., Cox, T., Bonnett, L., Harding, S., Marson, A., . . . Van der Hoek, M. (2016). Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research. Poster session presented at the meeting of 2016 MRC Festival of Medical Science. Liverpool.

Poster

10 YEAR OBSERVATIONAL STUDY OF PATIENT RELATED OUTCOMES DURING EXPANSION TO FULL POPULATION COVERAGE OF A SYSTEMATIC DIABETES EYE CARE PROGRAMME - THE LIVERPOOL DIABETIC EYE STUDY

Harding, S. P., Sampson, C., Cheyne, C. P., Broadbent, D. M., Stratton, I. M., Wang, A., & Garcia Finana, M. (2016). 10 YEAR OBSERVATIONAL STUDY OF PATIENT RELATED OUTCOMES DURING EXPANSION TO FULL POPULATION COVERAGE OF A SYSTEMATIC DIABETES EYE CARE PROGRAMME - THE LIVERPOOL DIABETIC EYE STUDY. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 26 (pp. E98). Retrieved from https://www.webofscience.com/

Conference Paper

10 year observational study of patient related outcomes during expansion to full population coverage of a systematic diabetes eye care programme - the Liverpool Diabetic Eye Study

Harding, S. P., Sampson, C., Cheyne, C., Broadbent, D., Wang, A., Mobayen-Rahni, M., . . . Finana, M. G. (2016). 10 year observational study of patient related outcomes during expansion to full population coverage of a systematic diabetes eye care programme - the Liverpool Diabetic Eye Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 57. Retrieved from https://www.webofscience.com/

Conference Paper

2015

INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY – THE LIVERPOOL RISK CALCULATION ENGINE

Harding, S. P., Eleuteri, A., Broadbent, D. M., Van der Hoek, M., Cheyne, C., Wang, A., . . . Fisher, A. C. (2015, June 26). INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY – THE LIVERPOOL RISK CALCULATION ENGINE. In European Journal of Ophthalmology Vol. 25 (pp. e7-e30). Turin. doi:10.5301/ejo.5000612

DOI
10.5301/ejo.5000612
Conference Paper

INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY: THE LIVERPOOL RISK CALCULATION ENGINE

Harding, S. P., Eleuteri, A., Broadbent, D. M., van der Hoek, M., Cheyne, C. P., Stratton, I. M., & Fisher, A. C. (2015). INDIVIDUALISED RISK-BASED SCREENING FOR DIABETIC RETINOPATHY: THE LIVERPOOL RISK CALCULATION ENGINE. EUROPEAN JOURNAL OF OPHTHALMOLOGY, 25(3), E12-E13. Retrieved from https://www.webofscience.com/

Journal article

2014

In Utero Exposure to Levetiracetam vs Valproate: Development & Language at 3 years of Age

Shallcross, R., Bromley, R. L., Cheyne, C. P., Garci­a-Finana, M., Irwin, B., Morrow, J., & Baker, G. A. (2014). In Utero Exposure to Levetiracetam vs Valproate: Development & Language at 3 years of Age. Neurology, 82(3), 213-221. doi:10.1212/WNL.0000000000000030

DOI
10.1212/WNL.0000000000000030
Journal article

In utero exposure to levetiracetam vs valproate

Shallcross, R., Bromley, R. L., Cheyne, C. P., García-Fiñana, M., Irwin, B., Morrow, J., & Baker, G. A. (2014). In utero exposure to levetiracetam vs valproate. Neurology, 82(3), 213-221. doi:10.1212/wnl.0000000000000030

DOI
10.1212/wnl.0000000000000030
Journal article

Musical ability enhances language skills in men and mathematical skills in women

Cheyne, C. P., Sluming, V., Cowell, P. E., Roberts, N., & Garcia-Finana, M. (2014). Musical ability enhances language skills in men and mathematical skills in women.

Journal article

Octopus and Humphrey perimetry in the detection of visual field loss in pituitary disease: peripheral kinetic versus central static

Rowe, F. J., Cheyne, C. P., García-Fiñana, M., Noonan, C. P., Howard, C., Smith, J., & Adeoye, J. (2014). Octopus and Humphrey perimetry in the detection of visual field loss in pituitary disease: peripheral kinetic versus central static.

Journal article

Prenatal exposure to antiepileptic drugs: Specific cognitive consequences in middle childhood

Bromley, R. L., Gummery, A., Shallcross, R., Mawer, G., Briggs, M., Clayton-Smith, J., . . . Mawer, G. (2014). Prenatal exposure to antiepileptic drugs: Specific cognitive consequences in middle childhood.

Journal article

2013

The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs

Bromley, R. L., Mawer, G. E., Briggs, M., Cheyne, C., Clayton-Smith, J., Garcia-Finana, M., . . . Shallcross, R. (2013). The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs. Journal of Neurology, Neurosurgery & Psychiatry, 84(6), 637-643. doi:10.1136/jnnp-2012-304270

DOI
10.1136/jnnp-2012-304270
Journal article

The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs.

Bromley, R. L., Mawer, G. E., Briggs, M., Cheyne, C., Clayton-Smith, J., García-Fiñana, M., . . . Liverpool and Manchester Neurodevelopment Group. (2013). The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs.. Journal of neurology, neurosurgery, and psychiatry, 84(6), 637-643. doi:10.1136/jnnp-2012-304270

DOI
10.1136/jnnp-2012-304270
Journal article

2011

In utero exposure to antiepileptic drugs: Cognitive development and functioning of the child

Bromley, R. L., Gummery, A., Shallcross, R., Mawer, G., Clayton-Smith, J., Cheyne, C., . . . Baker, G. A. (2011). In utero exposure to antiepileptic drugs: Cognitive development and functioning of the child. Reproductive Toxicology, 32(2), 155-156. doi:10.1016/j.reprotox.2011.06.016

DOI
10.1016/j.reprotox.2011.06.016
Journal article