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2024

Weight, Anthropometric and Metabolic Changes After Discontinuing Antiretroviral Therapy Containing Tenofovir Alafenamide in People With HIV.

Damas, J., Munting, A., Fellay, J., Haerry, D., Marzolini, C., Tarr, P. E., . . . Swiss HIV Cohort Study (SHCS). (2024). Weight, Anthropometric and Metabolic Changes After Discontinuing Antiretroviral Therapy Containing Tenofovir Alafenamide in People With HIV.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 79(4), 990-998. doi:10.1093/cid/ciae189

DOI
10.1093/cid/ciae189
Journal article

Vancomycin Dosing Strategy for the Treatment of Peritonitis in a Child on Automated Peritoneal Dialysis: A First Pediatric Case Report.

Haefliger, D., Chehade, H., Livio, F., Rodrigues-Veiga, V., Diezi, L., & Marzolini, C. (2024). Vancomycin Dosing Strategy for the Treatment of Peritonitis in a Child on Automated Peritoneal Dialysis: A First Pediatric Case Report.. Seminars in dialysis, 37(6), 461-465. doi:10.1111/sdi.13224

DOI
10.1111/sdi.13224
Journal article

Oritavancin use in patients with recurrent bone infections by methicillin-resistant Staphylococcus aureus with monitoring of concentrations.

Bongiovanni, M., Thoueille, P., Barda, B., Mercier, T., Marzolini, C., Ramponi, N., . . . Bernasconi, E. (2024). Oritavancin use in patients with recurrent bone infections by methicillin-resistant Staphylococcus aureus with monitoring of concentrations.. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 43(7), 1503-1504. doi:10.1007/s10096-024-04844-5

DOI
10.1007/s10096-024-04844-5
Journal article

Population Pharmacokinetics of Cabotegravir Following Oral Administration and Long-Acting Intramuscular Injection in Real-World People with HIV.

Thoueille, P., Saldanha, S. A., Schaller, F., Choong, E., Veuve, F., Munting, A., . . . Swiss HIV Cohort Study. (2024). Population Pharmacokinetics of Cabotegravir Following Oral Administration and Long-Acting Intramuscular Injection in Real-World People with HIV.. Clinical pharmacology and therapeutics, 115(6), 1450-1459. doi:10.1002/cpt.3240

DOI
10.1002/cpt.3240
Journal article

Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods for the therapeutic drug monitoring of cytotoxic anticancer drugs: An update.

Briki, M., Murisier, A., Guidi, M., Seydoux, C., Buclin, T., Marzolini, C., . . . Decosterd, L. A. (2024). Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods for the therapeutic drug monitoring of cytotoxic anticancer drugs: An update.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1236, 124039. doi:10.1016/j.jchromb.2024.124039

DOI
10.1016/j.jchromb.2024.124039
Journal article

Guidance for the Interpretation of Long-Acting Cabotegravir and Rilpivirine Concentrations Based on Real-World Therapeutic Drug Monitoring Data and Documented Failures.

Thoueille, P., Cavassini, M., Guidi, M., Buclin, T., Girardin, F. R., Decosterd, L. A., & Marzolini, C. (2024). Guidance for the Interpretation of Long-Acting Cabotegravir and Rilpivirine Concentrations Based on Real-World Therapeutic Drug Monitoring Data and Documented Failures.. Open forum infectious diseases, 11(2), ofae023. doi:10.1093/ofid/ofae023

DOI
10.1093/ofid/ofae023
Journal article

Antiretroviral Drug Exposure and Response in Obese and Morbidly Obese People With Human Immunodeficiency Virus (HIV): A Study Combining Modelling and Swiss HIV Cohort Data.

Berton, M., Bettonte, S., Stader, F., Decosterd, L., Tarr, P. E., Livio, F., . . . Swiss HIV Cohort Study. (2024). Antiretroviral Drug Exposure and Response in Obese and Morbidly Obese People With Human Immunodeficiency Virus (HIV): A Study Combining Modelling and Swiss HIV Cohort Data.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 78(1), 98-110. doi:10.1093/cid/ciad495

DOI
10.1093/cid/ciad495
Journal article

Real-world trough concentrations and effectiveness of long-acting cabotegravir and rilpivirine: a multicenter prospective observational study in Switzerland.

Thoueille, P., Saldanha, S. A., Schaller, F., Choong, E., Munting, A., Cavassini, M., . . . Swiss HIV Cohort Study. (2024). Real-world trough concentrations and effectiveness of long-acting cabotegravir and rilpivirine: a multicenter prospective observational study in Switzerland.. The Lancet regional health. Europe, 36, 100793. doi:10.1016/j.lanepe.2023.100793

DOI
10.1016/j.lanepe.2023.100793
Journal article

2023

Letter to the Editor: People living with HIV and NAFLD-A population left behind in the global effort for liver fibrosis screening?

Sebastiani, G., Milic, J., Tsochatzis, E. A., Marzolini, C., Betel, M., Bhagani, S., . . . Steatohepatitis in HIV Emerging Research (SHIVER) Network. (2023). Letter to the Editor: People living with HIV and NAFLD-A population left behind in the global effort for liver fibrosis screening?. Hepatology (Baltimore, Md.), 78(5), E87-E88. doi:10.1097/hep.0000000000000465

DOI
10.1097/hep.0000000000000465
Journal article

Effect of SLCO1B1 c.521T>C polymorphism on the lipid response to statins in people living with HIV on a boosted protease inhibitor-containing regimen.

Marzolini, C., Cavassini, M., Braun, D. L., Hachfeld, A., Bernasconi, E., Calmy, A., . . . Swiss HIV Cohort Study. (2023). Effect of SLCO1B1 c.521T>C polymorphism on the lipid response to statins in people living with HIV on a boosted protease inhibitor-containing regimen.. British journal of clinical pharmacology, 89(9), 2739-2746. doi:10.1111/bcp.15754

DOI
10.1111/bcp.15754
Journal article

Management of Drug Interactions with Inducers: Onset and Disappearance of Induction on Cytochrome P450 3A4 and Uridine Diphosphate Glucuronosyltransferase 1A1 Substrates.

Bettonte, S., Berton, M., Stader, F., Battegay, M., & Marzolini, C. (2023). Management of Drug Interactions with Inducers: Onset and Disappearance of Induction on Cytochrome P450 3A4 and Uridine Diphosphate Glucuronosyltransferase 1A1 Substrates.. European journal of drug metabolism and pharmacokinetics, 48(4), 353-362. doi:10.1007/s13318-023-00833-9

DOI
10.1007/s13318-023-00833-9
Journal article

What is the significance of the pharmacokinetic profile and potential drug-drug interactions of long-acting intramuscular cabotegravir and rilpivirine?

Bettonte, S., Berton, M., & Marzolini, C. (2023). What is the significance of the pharmacokinetic profile and potential drug-drug interactions of long-acting intramuscular cabotegravir and rilpivirine?. Expert opinion on drug metabolism & toxicology, 19(5), 243-247. doi:10.1080/17425255.2023.2223961

DOI
10.1080/17425255.2023.2223961
Journal article

Epigenetic ageing accelerates before antiretroviral therapy and decelerates after viral suppression in people with HIV in Switzerland: a longitudinal study over 17 years.

Schoepf, I. C., Esteban-Cantos, A., Thorball, C. W., Rodés, B., Reiss, P., Rodríguez-Centeno, J., . . . Swiss HIV Cohort Study. (2023). Epigenetic ageing accelerates before antiretroviral therapy and decelerates after viral suppression in people with HIV in Switzerland: a longitudinal study over 17 years.. The lancet. Healthy longevity, 4(5), e211-e218. doi:10.1016/s2666-7568(23)00037-5

DOI
10.1016/s2666-7568(23)00037-5
Journal article

Management of Drug-Drug Interactions Between Long-Acting Cabotegravir and Rilpivirine and Comedications With Inducing Properties: A Modeling Study.

Bettonte, S., Berton, M., Stader, F., Battegay, M., & Marzolini, C. (2023). Management of Drug-Drug Interactions Between Long-Acting Cabotegravir and Rilpivirine and Comedications With Inducing Properties: A Modeling Study.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 76(7), 1225-1236. doi:10.1093/cid/ciac901

DOI
10.1093/cid/ciac901
Journal article

Response to "A Case Report of Safe Coadministration of Amioradone With Short-Term Treatment Nirmatrelvir-Ritonavir"

Marzolini, C., & Khoo, S. (2023). Response to "A Case Report of Safe Coadministration of Amioradone With Short-Term Treatment Nirmatrelvir-Ritonavir". CLINICAL PHARMACOLOGY & THERAPEUTICS, 113(4), 770. doi:10.1002/cpt.2809

DOI
10.1002/cpt.2809
Journal article

Prevalence of Potentially Clinically Significant Drug-Drug Interactions With Antiretrovirals Against HIV Over Three Decades: A Systematic Review of the Literature

Hodge, D., Hodel, E. M., Hughes, E., Hazenberg, P., Granana Castillo, S., Gibbons, S., . . . Khoo, S. (2023). Prevalence of Potentially Clinically Significant Drug-Drug Interactions With Antiretrovirals Against HIV Over Three Decades: A Systematic Review of the Literature. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 92(2), 97-105. doi:10.1097/QAI.0000000000003122

DOI
10.1097/QAI.0000000000003122
Journal article

Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study.

Avery, E. F., Kleynhans, J. N., Ledergerber, B., Schoepf, I. C., Thorball, C. W., Kootstra, N. A., . . . Swiss HIV Cohort Study. (2023). Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 76(11), 1969-1979. doi:10.1093/cid/ciad033

DOI
10.1093/cid/ciad033
Journal article

Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons With Human Immunodeficiency Virus (HIV): The Swiss HIV Cohort Study.

Schoepf, I. C., Thorball, C. W., Kovari, H., Ledergerber, B., Buechel, R. R., Calmy, A., . . . Swiss HIV Cohort Study. (2023). Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons With Human Immunodeficiency Virus (HIV): The Swiss HIV Cohort Study.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 76(1), 48-56. doi:10.1093/cid/ciac758

DOI
10.1093/cid/ciac758
Journal article

Real-World Trough Concentrations and Effectiveness of Long-Acting Cabotegravir and Rilpivirine: A Multicenter Prospective Observational Study in Switzerland

DOI
10.2139/ssrn.4584084
Preprint

2022

Recommendations for the Management of Drug-Drug Interactions Between the COVID-19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications

Marzolini, C., Kuritzkes, D. R., Marra, F., Boyle, A., Gibbons, S., Flexner, C., . . . Khoo, S. (2022). Recommendations for the Management of Drug-Drug Interactions Between the COVID-19 Antiviral Nirmatrelvir/Ritonavir (Paxlovid) and Comedications. CLINICAL PHARMACOLOGY & THERAPEUTICS, 112(6), 1191-1200. doi:10.1002/cpt.2646

DOI
10.1002/cpt.2646
Journal article

Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study.

Aebi-Popp, K., Kahlert, C. R., Crisinel, P. -A., Decosterd, L., Saldanha, S. A., Hoesli, I., . . . Swiss Mother and Child HIV Cohort Study (SHCS). (2022). Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study.. The Journal of antimicrobial chemotherapy, 77(12), 3436-3442. doi:10.1093/jac/dkac337

DOI
10.1093/jac/dkac337
Journal article

Anticholinergic and Sedative Medications Are Associated With Neurocognitive Performance of Well Treated People With Human Immunodeficiency Virus.

Jakeman, B., Scherrer, A. U., Darling, K. E. A., Damas, J., Bieler-Aeschlimann, M., Hasse, B., . . . NAMACO Study Group, a Swiss HIV Cohort Study . (2022). Anticholinergic and Sedative Medications Are Associated With Neurocognitive Performance of Well Treated People With Human Immunodeficiency Virus.. Open forum infectious diseases, 9(9), ofac457. doi:10.1093/ofid/ofac457

DOI
10.1093/ofid/ofac457
Journal article

Repository Describing the Anatomical, Physiological, and Biological Changes in an Obese Population to Inform Physiologically Based Pharmacokinetic Models.

Berton, M., Bettonte, S., Stader, F., Battegay, M., & Marzolini, C. (2022). Repository Describing the Anatomical, Physiological, and Biological Changes in an Obese Population to Inform Physiologically Based Pharmacokinetic Models.. Clinical pharmacokinetics, 61(9), 1251-1270. doi:10.1007/s40262-022-01132-3

DOI
10.1007/s40262-022-01132-3
Journal article

Evaluating the risk of drug-drug interactions with pharmacokinetic boosters: the case of ritonavir-enhanced nirmatrelvir to prevent severe COVID-19.

Girardin, F., Manuel, O., Marzolini, C., & Buclin, T. (2022). Evaluating the risk of drug-drug interactions with pharmacokinetic boosters: the case of ritonavir-enhanced nirmatrelvir to prevent severe COVID-19.. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 28(8), 1044-1046. doi:10.1016/j.cmi.2022.03.030

DOI
10.1016/j.cmi.2022.03.030
Journal article

Real-Life Therapeutic Concentration Monitoring of Long-Acting Cabotegravir and Rilpivirine: Preliminary Results of an Ongoing Prospective Observational Study in Switzerland.

Thoueille, P., Alves Saldanha, S., Schaller, F., Munting, A., Cavassini, M., Braun, D., . . . On Behalf Of The Swiss Hiv Cohort Study. (2022). Real-Life Therapeutic Concentration Monitoring of Long-Acting Cabotegravir and Rilpivirine: Preliminary Results of an Ongoing Prospective Observational Study in Switzerland.. Pharmaceutics, 14(8), 1588. doi:10.3390/pharmaceutics14081588

DOI
10.3390/pharmaceutics14081588
Journal article

Practical recommendations to combine small-molecule inhibitors and direct oral anticoagulants in patients with nonsmall cell lung cancer.

Otten, L. S., Piet, B., van den Heuvel, M. M., Marzolini, C., van Geel, R. M. J. M., Gulikers, J. L., . . . Ter Heine, R. (2022). Practical recommendations to combine small-molecule inhibitors and direct oral anticoagulants in patients with nonsmall cell lung cancer.. European respiratory review : an official journal of the European Respiratory Society, 31(164), 220004. doi:10.1183/16000617.0004-2022

DOI
10.1183/16000617.0004-2022
Journal article

Drug interactions: a review of the unseen danger of experimental COVID-19 therapies (vol 75, pg 3417, 2020)

Hodge, D., Marra, F., Marzolini, C., Boyle, A., Gibbons, S., Siccardi, M., . . . Khoo, S. (2022). Drug interactions: a review of the unseen danger of experimental COVID-19 therapies (vol 75, pg 3417, 2020). JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 77(7), 2050. doi:10.1093/jac/dkac111

DOI
10.1093/jac/dkac111
Journal article

Sex-related pharmacokinetic differences with aging.

Stader, F., & Marzolini, C. (2022). Sex-related pharmacokinetic differences with aging.. European geriatric medicine, 13(3), 559-565. doi:10.1007/s41999-021-00587-0

DOI
10.1007/s41999-021-00587-0
Journal article

Telomere Length Declines in Persons With Human Immunodeficiency Virus Before Antiretroviral Therapy Start but Not After Viral Suppression: A Longitudinal Study Over >17 Years.

Schoepf, I. C., Thorball, C. W., Ledergerber, B., Kootstra, N. A., Reiss, P., Raffenberg, M., . . . Tarr, P. E. (2022). Telomere Length Declines in Persons With Human Immunodeficiency Virus Before Antiretroviral Therapy Start but Not After Viral Suppression: A Longitudinal Study Over >17 Years.. The Journal of infectious diseases, 225(9), 1581-1591. doi:10.1093/infdis/jiab603

DOI
10.1093/infdis/jiab603
Journal article

Prescribing Nirmatrelvir-Ritonavir: How to Recognize and Manage Drug-Drug Interactions

Marzolini, C., Kuritzkes, D. R., Marra, F., Boyle, A., Gibbons, S., Flexner, C., . . . Khoo, S. (2022). Prescribing Nirmatrelvir-Ritonavir: How to Recognize and Manage Drug-Drug Interactions. ANNALS OF INTERNAL MEDICINE, 175(5), 744-+. doi:10.7326/M22-0281

DOI
10.7326/M22-0281
Journal article

Drug-Drug Interaction Potential with Once-Weekly Isoniazid/Rifapentine (3HP) for the Treatment of Latent Tuberculosis Infection

Marzolini, C., Gibbons, S., van Oosterhout, J. J., & Khoo, S. (2022). Drug-Drug Interaction Potential with Once-Weekly Isoniazid/Rifapentine (3HP) for the Treatment of Latent Tuberculosis Infection. CLINICAL PHARMACOKINETICS, 61(3), 339-346. doi:10.1007/s40262-021-01098-8

DOI
10.1007/s40262-021-01098-8
Journal article

Fluvoxamine for the treatment of COVID-19

Marzolini, C., Marra, F., Boyle, A., Khoo, S., & Back, D. J. (2022). Fluvoxamine for the treatment of COVID-19. LANCET GLOBAL HEALTH, 10(3), E331. Retrieved from https://www.webofscience.com/

Journal article

Cohort Profile Update: The Swiss HIV Cohort Study (SHCS).

Scherrer, A. U., Traytel, A., Braun, D. L., Calmy, A., Battegay, M., Cavassini, M., . . . Swiss HIV Cohort Study (SHCS). (2022). Cohort Profile Update: The Swiss HIV Cohort Study (SHCS).. International journal of epidemiology, 51(1), 33-34j. doi:10.1093/ije/dyab141

DOI
10.1093/ije/dyab141
Journal article

Anticholinergic medication use in elderly people living with HIV and self-reported neurocognitive impairment: a prospective cohort study.

Jakeman, B., Scherrer, A., Battegay, M., Gunthard, H. F., Hachfeld, A., Calmy, A., . . . Marzolini, C. (2022). Anticholinergic medication use in elderly people living with HIV and self-reported neurocognitive impairment: a prospective cohort study.. The Journal of antimicrobial chemotherapy, 77(2), 492-499. doi:10.1093/jac/dkab386

DOI
10.1093/jac/dkab386
Journal article

Collaborative challenges of multi-cohort project in pharmacogenetics: why time is essential for meaningful collaborations (Preprint)

DOI
10.2196/preprints.36759
Preprint

2021

Coronary Artery Disease-Associated and Longevity-Associated Polygenic Risk Scores for Prediction of Coronary Artery Disease Events in Persons Living With Human Immunodeficiency Virus: The Swiss HIV Cohort Study.

Schoepf, I. C., Thorball, C. W., Ledergerber, B., Engel, T., Raffenberg, M., Kootstra, N. A., . . . Swiss HIV Cohort Study. (2021). Coronary Artery Disease-Associated and Longevity-Associated Polygenic Risk Scores for Prediction of Coronary Artery Disease Events in Persons Living With Human Immunodeficiency Virus: The Swiss HIV Cohort Study.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 73(9), 1597-1604. doi:10.1093/cid/ciab521

DOI
10.1093/cid/ciab521
Journal article

Cohort-Derived Machine Learning Models for Individual Prediction of Chronic Kidney Disease in People Living With Human Immunodeficiency Virus: A Prospective Multicenter Cohort Study.

Roth, J. A., Radevski, G., Marzolini, C., Rauch, A., Günthard, H. F., Kouyos, R. D., . . . Swiss HIV Cohort Study (SHCS). (2021). Cohort-Derived Machine Learning Models for Individual Prediction of Chronic Kidney Disease in People Living With Human Immunodeficiency Virus: A Prospective Multicenter Cohort Study.. The Journal of infectious diseases, 224(7), 1198-1208. doi:10.1093/infdis/jiaa236

DOI
10.1093/infdis/jiaa236
Journal article

Polypharmacy and risk of admission to hospital in people ageing with HIV: what is the contribution of drug-drug interactions?

Allavena, C., & Marzolini, C. (2021). Polypharmacy and risk of admission to hospital in people ageing with HIV: what is the contribution of drug-drug interactions?. The lancet. Healthy longevity, 2(10), e606-e607. doi:10.1016/s2666-7568(21)00227-0

DOI
10.1016/s2666-7568(21)00227-0
Journal article

Recognition and management of clinically significant drug-drug interactions between antiretrovirals and co-medications in a cohort of people living with HIV in rural Tanzania: a prospective questionnaire-based study.

Kuemmerle, A., Sikalengo, G., Vanobberghen, F., Ndege, R. C., Foe, G., Schlaeppi, C., . . . KIULARCO Study Group. (2021). Recognition and management of clinically significant drug-drug interactions between antiretrovirals and co-medications in a cohort of people living with HIV in rural Tanzania: a prospective questionnaire-based study.. The Journal of antimicrobial chemotherapy, 76(10), 2681-2689. doi:10.1093/jac/dkab254

DOI
10.1093/jac/dkab254
Journal article

Lactic acidosis and hyperlactatemia associated with lamivudine accumulation and sepsis in a kidney transplant recipient-a case report and review of the literature.

Hollinger, A., Cueni, N., Marzolini, C., Dickenmann, M., Landmann, E., Battegay, M., . . . Leuppi-Taegtmeyer, A. (2021). Lactic acidosis and hyperlactatemia associated with lamivudine accumulation and sepsis in a kidney transplant recipient-a case report and review of the literature.. AIDS research and therapy, 18(1), 56. doi:10.1186/s12981-021-00382-8

DOI
10.1186/s12981-021-00382-8
Journal article

Population pharmacokinetic modelling to quantify the magnitude of drug-drug interactions between amlodipine and antiretroviral drugs.

Courlet, P., Guidi, M., Alves Saldanha, S., Cavassini, M., Stoeckle, M., Buclin, T., . . . Csajka, C. (2021). Population pharmacokinetic modelling to quantify the magnitude of drug-drug interactions between amlodipine and antiretroviral drugs.. European journal of clinical pharmacology, 77(7), 979-987. doi:10.1007/s00228-020-03060-2

DOI
10.1007/s00228-020-03060-2
Journal article

Cardiovascular adverse effects of lopinavir/ritonavir and hydroxychloroquine in COVID-19 patients: Cases from a single pharmacovigilance centre.

Istampoulouoglou, I., Zimmermanns, B., Grandinetti, T., Marzolini, C., Harings-Kaim, A., Koechlin-Lemke, S., . . . Leuppi-Taegtmeyer, A. B. (2021). Cardiovascular adverse effects of lopinavir/ritonavir and hydroxychloroquine in COVID-19 patients: Cases from a single pharmacovigilance centre.. Global cardiology science & practice, 2021(2), e202111. doi:10.21542/gcsp.2021.11

DOI
10.21542/gcsp.2021.11
Journal article

Physiologically-Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV.

Stader, F., Courlet, P., Decosterd, L. A., Battegay, M., & Marzolini, C. (2021). Physiologically-Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV.. Clinical pharmacology and therapeutics, 109(4), 1025-1029. doi:10.1002/cpt.2178

DOI
10.1002/cpt.2178
Journal article

Pharmacokinetic/Pharmacodynamic Modelling to Describe the Cholesterol Lowering Effect of Rosuvastatin in People Living with HIV.

Courlet, P., Guidi, M., Alves Saldanha, S., Stader, F., Traytel, A., Cavassini, M., . . . and the Swiss HIV Cohort Study. (2021). Pharmacokinetic/Pharmacodynamic Modelling to Describe the Cholesterol Lowering Effect of Rosuvastatin in People Living with HIV.. Clinical pharmacokinetics, 60(3), 379-390. doi:10.1007/s40262-020-00946-3

DOI
10.1007/s40262-020-00946-3
Journal article

Prescribing in COVID-19 patients: Should we take into account inflammation?

Marzolini, C., Battegay, M., Sendi, P., & Back, D. J. (2021). Prescribing in COVID-19 patients: Should we take into account inflammation?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(3), 719-721. doi:10.1111/bcp.14524

DOI
10.1111/bcp.14524
Journal article

Analysis of inappropriate prescribing in elderly patients of the Swiss HIV Cohort Study reveals gender inequity.

Livio, F., Deutschmann, E., Moffa, G., Rrustemi, F., Stader, F., Elzi, L., . . . Swiss HIV Cohort Study. (2021). Analysis of inappropriate prescribing in elderly patients of the Swiss HIV Cohort Study reveals gender inequity.. The Journal of antimicrobial chemotherapy, 76(3), 758-764. doi:10.1093/jac/dkaa505

DOI
10.1093/jac/dkaa505
Journal article

Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation

Stader, F., Courlet, P., Kinvig, H., Battegay, M., Decosterd, L. A., Penny, M. A., . . . Marzolini, C. (2021). Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(2), 458-470. doi:10.1111/bcp.14402

DOI
10.1111/bcp.14402
Journal article

Global surveillance of potential antiviral drug resistance in SARS-CoV-2: proof of concept focussing on the RNA-dependent RNA polymerase

DOI
10.1101/2020.12.28.20248663
Preprint

2020

Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect

Stader, F., Khoo, S., Stoeckle, M., Back, D., Hirsch, H. H., Battegay, M., & Marzolini, C. (2020). Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 75(10), 3084-3086. doi:10.1093/jac/dkaa253

DOI
10.1093/jac/dkaa253
Journal article

Influence of Drug-Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV.

Courlet, P., Decosterd, L. A., Alves Saldanha, S., Cavassini, M., Stader, F., Stoeckle, M., . . . Swiss HIV Cohort Study. (2020). Influence of Drug-Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV.. Clinical pharmacokinetics, 59(8), 1037-1048. doi:10.1007/s40262-020-00876-0

DOI
10.1007/s40262-020-00876-0
Journal article

Changes in Renal Function After Switching From TDF to TAF in HIV-Infected Individuals: A Prospective Cohort Study.

Surial, B., Ledergerber, B., Calmy, A., Cavassini, M., Günthard, H. F., Kovari, H., . . . Swiss HIV Cohort Study. (2020). Changes in Renal Function After Switching From TDF to TAF in HIV-Infected Individuals: A Prospective Cohort Study.. The Journal of infectious diseases, 222(4), 637-645. doi:10.1093/infdis/jiaa125

DOI
10.1093/infdis/jiaa125
Journal article

Polypharmacy and Drug-Drug Interactions in People Living With Human Immunodeficiency Virus in the Region of Madrid, Spain: A Population-Based Study

Lopez-Centeno, B., Badenes-Olmedo, C., Mataix-Sanjuan, A., McAllister, K., Bellon, J. M., Gibbons, S., . . . Berenguer, J. (2020). Polypharmacy and Drug-Drug Interactions in People Living With Human Immunodeficiency Virus in the Region of Madrid, Spain: A Population-Based Study. In CLINICAL INFECTIOUS DISEASES Vol. 71 (pp. 353-362). doi:10.1093/cid/ciz811

DOI
10.1093/cid/ciz811
Conference Paper

Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations

DOI
10.1101/2020.07.05.20146878
Preprint

Real-life management of drug-drug interactions between antiretrovirals and statins.

Courlet, P., Livio, F., Alves Saldanha, S., Scherrer, A., Battegay, M., Cavassini, M., . . . Swiss HIV Cohort Study. (2020). Real-life management of drug-drug interactions between antiretrovirals and statins.. The Journal of antimicrobial chemotherapy, 75(7), 1972-1980. doi:10.1093/jac/dkaa099

DOI
10.1093/jac/dkaa099
Journal article

Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.

Courlet, P., Alves Saldanha, S., Cavassini, M., Marzolini, C., Choong, E., Csajka, C., . . . Decosterd, L. A. (2020). Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.. Journal of mass spectrometry : JMS, 55(6), e4506. doi:10.1002/jms.4506

DOI
10.1002/jms.4506
Journal article

Aging does not impact drug--drug interaction magnitudes with antiretrovirals.

Stader, F., Decosterd, L., Stoeckle, M., Cavassini, M., Battegay, M., Saldanha, S. A., . . . and the Swiss HIV Cohort Study. (2020). Aging does not impact drug--drug interaction magnitudes with antiretrovirals.. AIDS (London, England), 34(6), 949-952. doi:10.1097/qad.0000000000002489

DOI
10.1097/qad.0000000000002489
Journal article

New Drugs for NASH and HIV Infection: Great Expectations for a Great Need.

Guaraldi, G., Maurice, J. B., Marzolini, C., Monteith, K., Milic, J., Tsochatzis, E., . . . SHIVER Network. (2020). New Drugs for NASH and HIV Infection: Great Expectations for a Great Need.. Hepatology (Baltimore, Md.), 71(5), 1831-1844. doi:10.1002/hep.31177

DOI
10.1002/hep.31177
Journal article

Pharmacokinetic profiles of boosted darunavir, dolutegravir and lamivudine in aging people living with HIV.

Courlet, P., Stader, F., Guidi, M., Alves Saldanha, S., Stoeckle, M., Cavassini, M., . . . Swiss HIV Cohort Study. (2020). Pharmacokinetic profiles of boosted darunavir, dolutegravir and lamivudine in aging people living with HIV.. AIDS (London, England), 34(1), 103-108. doi:10.1097/qad.0000000000002372

DOI
10.1097/qad.0000000000002372
Journal article

Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective cohort study.

Schlaeppi, C., Vanobberghen, F., Sikalengo, G., Glass, T. R., Ndege, R. C., Foe, G., . . . Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) study group. (2020). Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective cohort study.. HIV medicine, 21(1), 53-63. doi:10.1111/hiv.12801

DOI
10.1111/hiv.12801
Journal article

2019

Current Challenges and Solutions in Research and Clinical Care of Older Persons Living with HIV: Findings Presented at the 9th International Workshop on HIV and Aging.

Sundermann, E. E., Erlandson, K. M., Pope, C. N., Rubtsova, A., Montoya, J., Moore, A. A., . . . Moore, D. J. (2019). Current Challenges and Solutions in Research and Clinical Care of Older Persons Living with HIV: Findings Presented at the 9th International Workshop on HIV and Aging.. In AIDS research and human retroviruses Vol. 35 (pp. 985-998). doi:10.1089/aid.2019.0100

DOI
10.1089/aid.2019.0100
Conference Paper

Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics.

Brockhaus, L., Goldblum, D., Eggenschwiler, L., Zimmerli, S., & Marzolini, C. (2019). Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics.. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(11), 1364-1369. doi:10.1016/j.cmi.2019.01.017

DOI
10.1016/j.cmi.2019.01.017
Journal article

Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting.

Barcelo, C., Aouri, M., Courlet, P., Guidi, M., Braun, D. L., Günthard, H. F., . . . Swiss HIV Cohort Study. (2019). Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting.. The Journal of antimicrobial chemotherapy, 74(9), 2690-2697. doi:10.1093/jac/dkz217

DOI
10.1093/jac/dkz217
Journal article

UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.

Courlet, P., Spaggiari, D., Desfontaine, V., Cavassini, M., Alves Saldanha, S., Buclin, T., . . . Decosterd, L. -A. (2019). UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1125, 121733. doi:10.1016/j.jchromb.2019.121733

DOI
10.1016/j.jchromb.2019.121733
Journal article

Emtricitabine and lamivudine concentrations in saliva: a simple suitable test for treatment adherence.

Courlet, P., Decosterd, L. A., Brown, J. A., Alves Saldanha, S., Marzolini, C., Cavassini, M., . . . Swiss HIV Cohort Study. (2019). Emtricitabine and lamivudine concentrations in saliva: a simple suitable test for treatment adherence.. The Journal of antimicrobial chemotherapy, 74(8), 2468-2470. doi:10.1093/jac/dkz181

DOI
10.1093/jac/dkz181
Journal article

Prescribing issues in elderly individuals living with HIV.

Marzolini, C., & Livio, F. (2019). Prescribing issues in elderly individuals living with HIV.. Expert review of clinical pharmacology, 12(7), 643-659. doi:10.1080/17512433.2019.1627200

DOI
10.1080/17512433.2019.1627200
Journal article

Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes

Stader, F., Siccardi, M., Battegay, M., Kinvig, H., Penny, M. A., & Marzolini, C. (2019). Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes. CLINICAL PHARMACOKINETICS, 58(4), 483-501. doi:10.1007/s40262-018-0709-7

DOI
10.1007/s40262-018-0709-7
Journal article

Pharmacokinetics, Placental and Breastmilk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV.

Hodel, E. M., Marzolini, C., Waitt, C., & Rakhmanina, N. (2019). Pharmacokinetics, Placental and Breastmilk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV.. Current Pharmaceutical Design. doi:10.2174/1381612825666190320162507

DOI
10.2174/1381612825666190320162507
Journal article

Drug interaction profiles for first line antiretroviral therapy and selected fixed-dose antiretroviral combinations over 20 years of the Liverpool Drug Interaction website

Gibbons, S., Marzolini, C., Moss, C., McAllister, K., Chiong, J., Back, D., & Khoo, S. (2019). Drug interaction profiles for first line antiretroviral therapy and selected fixed-dose antiretroviral combinations over 20 years of the Liverpool Drug Interaction website. In HIV MEDICINE Vol. 20 (pp. 44-45). Retrieved from https://www.webofscience.com/

Conference Paper

Escitalopram population pharmacokinetics in people living with human immunodeficiency virus and in the psychiatric population: Drug-drug interactions and probability of target attainment.

Courlet, P., Guidi, M., Glatard, A., Alves Saldanha, S., Cavassini, M., Buclin, T., . . . Swiss HIV Cohort Study. (2019). Escitalopram population pharmacokinetics in people living with human immunodeficiency virus and in the psychiatric population: Drug-drug interactions and probability of target attainment.. British journal of clinical pharmacology, 85(9), 2022-2032. doi:10.1111/bcp.13994

DOI
10.1111/bcp.13994
Journal article

2018

Boosted darunavir, emtricitabine and tenofovir pharmacokinetics in sthe early and late postgastric bypass surgery periods.

Baettig, V., Courlet, P., Delko, T., Battegay, M., & Marzolini, C. (2018). Boosted darunavir, emtricitabine and tenofovir pharmacokinetics in sthe early and late postgastric bypass surgery periods.. AIDS (London, England), 32(13), 1903-1905. doi:10.1097/qad.0000000000001913

DOI
10.1097/qad.0000000000001913
Journal article

HIV and Aging - Perhaps Not as Dramatic as We Feared?

Engel, T., Raffenberg, M., Marzolini, C., Cavassini, M., Kovari, H., Hasse, B., & Tarr, P. E. (2018). HIV and Aging - Perhaps Not as Dramatic as We Feared?. Gerontology, 64(5), 446-456. doi:10.1159/000489172

DOI
10.1159/000489172
Journal article

Analysis of Clinical Drug-Drug Interaction Data To Predict Magnitudes of Uncharacterized Interactions between Antiretroviral Drugs and Comedications

Stader, F., Kinvig, H., Battegay, M., Khoo, S., Owen, A., Siccardi, M., & Marzolini, C. (2018). Analysis of Clinical Drug-Drug Interaction Data To Predict Magnitudes of Uncharacterized Interactions between Antiretroviral Drugs and Comedications. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(7). doi:10.1128/AAC.00717-18

DOI
10.1128/AAC.00717-18
Journal article

2017

Health care provider communication training in rural Tanzania empowers HIV-infected patients on antiretroviral therapy to discuss adherence problems.

Erb, S., Letang, E., Glass, T. R., Natamatungiro, A., Mnzava, D., Mapesi, H., . . . Kilombero Ulanga Antiretroviral Cohort (KIULARCO) study group. (2017). Health care provider communication training in rural Tanzania empowers HIV-infected patients on antiretroviral therapy to discuss adherence problems.. HIV medicine, 18(9), 623-634. doi:10.1111/hiv.12499

DOI
10.1111/hiv.12499
Journal article

Darunavir concentrations in CSF of HIV-infected individuals when boosted with cobicistat versus ritonavir.

Bartels, H., Decosterd, L., Battegay, M., & Marzolini, C. (2017). Darunavir concentrations in CSF of HIV-infected individuals when boosted with cobicistat versus ritonavir.. The Journal of antimicrobial chemotherapy, 72(9), 2574-2577. doi:10.1093/jac/dkx165

DOI
10.1093/jac/dkx165
Journal article

Adverse events of raltegravir and dolutegravir.

Elzi, L., Erb, S., Furrer, H., Cavassini, M., Calmy, A., Vernazza, P., . . . Swiss HIV Cohort Study Group. (2017). Adverse events of raltegravir and dolutegravir.. AIDS (London, England), 31(13), 1853-1858. doi:10.1097/qad.0000000000001590

DOI
10.1097/qad.0000000000001590
Journal article

Dolutegravir plasma levels after gastric bypass surgery.

Piso, R. J., Battegay, M., & Marzolini, C. (2017). Dolutegravir plasma levels after gastric bypass surgery.. AIDS (London, England), 31(7), 1052-1054. doi:10.1097/qad.0000000000001438

DOI
10.1097/qad.0000000000001438
Journal article

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes

Marzolini, C., Rajoli, R., Battegay, M., Elzi, L., Back, D., & Siccardi, M. (2017). Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes. CLINICAL PHARMACOKINETICS, 56(4), 409-420. doi:10.1007/s40262-016-0447-7

DOI
10.1007/s40262-016-0447-7
Journal article

Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection

Seden, K., Gibbons, S., Marzolini, C., Schapiro, J. M., Burger, D. M., Back, D. J., & Khoo, S. H. (2017). Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection. PLOS ONE, 12(3). doi:10.1371/journal.pone.0173509

DOI
10.1371/journal.pone.0173509
Journal article

2016

Cobicistat versus ritonavir boosting and differences in the drug-drug interaction profiles with co-medications

Marzolini, C., Gibbons, S., Khoo, S., & Back, D. (2016). Cobicistat versus ritonavir boosting and differences in the drug-drug interaction profiles with co-medications. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 71(7), 1755-1758. doi:10.1093/jac/dkw032

DOI
10.1093/jac/dkw032
Journal article

Essentials from the 2015 European AIDS Clinical Society (EACS) guidelines for the treatment of adult HIV-positive persons.

Ryom, L., Boesecke, C., Gisler, V., Manzardo, C., Rockstroh, J. K., Puoti, M., . . . EACS Governing Board. (2016). Essentials from the 2015 European AIDS Clinical Society (EACS) guidelines for the treatment of adult HIV-positive persons.. HIV medicine, 17(2), 83-88. doi:10.1111/hiv.12322

DOI
10.1111/hiv.12322
Journal article

2015

Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies

Moss, D. M., Marzolini, C., Rajoli, R. K. R., & Siccardit, M. (2015). Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 11(8), 1203-1217. doi:10.1517/17425255.2015.1037278

DOI
10.1517/17425255.2015.1037278
Journal article

Etravirine: a good option for concomitant use with chemotherapy for Hodgkin's lymphoma.

Kurz, M., Stoeckle, M., Krasniqi, F., Battegay, M., & Marzolini, C. (2015). Etravirine: a good option for concomitant use with chemotherapy for Hodgkin's lymphoma.. International journal of STD & AIDS, 26(3), 212-214. doi:10.1177/0956462414533517

DOI
10.1177/0956462414533517
Journal article

Impact of body weight on virological and immunological responses to efavirenz-containing regimens in HIV-infected, treatment-naive adults

Marzolini, C., Sabin, C., Raffi, F., Siccardi, M., Mussini, C., Launay, O., . . . Battegay, M. (2015). Impact of body weight on virological and immunological responses to efavirenz-containing regimens in HIV-infected, treatment-naive adults. AIDS, 29(2), 193-200. doi:10.1097/QAD.0000000000000530

DOI
10.1097/QAD.0000000000000530
Journal article

2014

Gastrointestinal bleeding associated with rivaroxaban administration in a treated patient infected with human immunodeficiency virus.

Lakatos, B., Stoeckle, M., Elzi, L., Battegay, M., & Marzolini, C. (2014). Gastrointestinal bleeding associated with rivaroxaban administration in a treated patient infected with human immunodeficiency virus.. Swiss medical weekly, 144, w13906. doi:10.4414/smw.2014.13906

DOI
10.4414/smw.2014.13906
Journal article

2013

Erratum to: Prediction of Drug–Drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach

Siccardi, M., Marzolini, C., Seden, K., Almond, L., Kirov, A., Khoo, S., . . . Back, D. (2013). Erratum to: Prediction of Drug–Drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach. Clinical Pharmacokinetics, 52(7), 613-614. doi:10.1007/s40262-013-0066-5

DOI
10.1007/s40262-013-0066-5
Journal article

Prediction of drug-drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach

Siccardi, M., Marzolini, C., Seden, K., Almond, L., Kirov, A., Khoo, S., . . . Back, D. (2013). Prediction of drug-drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach. CLINICAL PHARMACOKINETICS, 52(7), 583-592. doi:10.1007/s40262-013-0056-7

DOI
10.1007/s40262-013-0056-7
Journal article

The brain entry of HIV-1 protease inhibitors is facilitated when used in combination.

Marzolini, C., Mueller, R., Li-Blatter, X., Battegay, M., & Seelig, A. (2013). The brain entry of HIV-1 protease inhibitors is facilitated when used in combination.. Molecular pharmaceutics, 10(6), 2340-2349. doi:10.1021/mp300712a

DOI
10.1021/mp300712a
Journal article

Pharmacogenetics-based population pharmacokinetic analysis of etravirine in HIV-1 infected individuals.

Lubomirov, R., Arab-Alameddine, M., Rotger, M., Fayet-Mello, A., Martinez, R., Guidi, M., . . . Swiss HIV Cohort Study. (2013). Pharmacogenetics-based population pharmacokinetic analysis of etravirine in HIV-1 infected individuals.. Pharmacogenetics and genomics, 23(1), 9-18. doi:10.1097/fpc.0b013e32835ade82

DOI
10.1097/fpc.0b013e32835ade82
Journal article

2012

Efavirenz in an obese HIV-infected patient - a report and an <i>in vitro</i>-<i>in vivo</i> extrapolation model indicate risk of underdosing

de Roche, M., Siccardi, M., Stoeckle, M., Livio, F., Back, D., Battegay, M., & Marzolini, C. (2012). Efavirenz in an obese HIV-infected patient - a report and an <i>in vitro</i>-<i>in vivo</i> extrapolation model indicate risk of underdosing. ANTIVIRAL THERAPY, 17(7), 1381-1384. doi:10.3851/IMP2107

DOI
10.3851/IMP2107
Journal article

Maternal antiretroviral prophylaxis and breastfeeding.

Marzolini, C., & Gray, G. E. (2012). Maternal antiretroviral prophylaxis and breastfeeding.. Antiviral therapy, 17(8), 1503-1506. doi:10.3851/imp2314

DOI
10.3851/imp2314
Journal article

Prediction of drug-drug interactions between various antidepressants and ritonavir using a physiologically based pharmacokinetic model

Siccardi, M., Marzolini, C., Seden, K., Almond, L., Kirov, A., Khoo, S., . . . Back, D. (2012). Prediction of drug-drug interactions between various antidepressants and ritonavir using a physiologically based pharmacokinetic model. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 15, 60. doi:10.7448/IAS.15.6.18339

DOI
10.7448/IAS.15.6.18339
Journal article

Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an <i>In Vitro</i>-<i>In Vivo</i> Extrapolation Model

Siccardi, M., Almond, L., Schipani, A., Csajka, C., Marzolini, C., Wyen, C., . . . Back, D. (2012). Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an <i>In Vitro</i>-<i>In Vivo</i> Extrapolation Model. CLINICAL PHARMACOLOGY & THERAPEUTICS, 92(4), 494-502. doi:10.1038/clpt.2012.61

DOI
10.1038/clpt.2012.61
Journal article

2011

[Drug-drug interactions with HIV treatments].

Mossdorf, E., Marzolini, C., Fasel, D., Mello Fayet, A., Blum, C., Donath, M., & Battegay, M. (2011). [Drug-drug interactions with HIV treatments].. Praxis, 100(19), 1193-1196. doi:10.1024/1661-8157/a000673

DOI
10.1024/1661-8157/a000673
Journal article

Ageing with HIV: medication use and risk for potential drug-drug interactions

Marzolini, C., Back, D., Weber, R., Furrer, H., Cavassini, M., Calmy, A., . . . Yerly, S. (2011). Ageing with HIV: medication use and risk for potential drug-drug interactions. Journal of Antimicrobial Chemotherapy, 66(9), 2107-2111. doi:10.1093/jac/dkr248

DOI
10.1093/jac/dkr248
Journal article

Ageing with HIV: medication use and risk for potential drug-drug interactions.

Marzolini, C., Back, D., Weber, R., Furrer, H., Cavassini, M., Calmy, A., . . . Swiss HIV Cohort Study Members. (2011). Ageing with HIV: medication use and risk for potential drug-drug interactions.. The Journal of antimicrobial chemotherapy, 66(9), 2107-2111. doi:10.1093/jac/dkr248

DOI
10.1093/jac/dkr248
Journal article

2010

ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir.

Lubomirov, R., di Iulio, J., Fayet, A., Colombo, S., Martinez, R., Marzolini, C., . . . Swiss HIV Cohort Study. (2010). ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir.. Pharmacogenetics and genomics, 20(4), 217-230. doi:10.1097/fpc.0b013e328336eee4

DOI
10.1097/fpc.0b013e328336eee4
Journal article

Prevalence of comedications and effect of potential drug–drug interactions in the Swiss HIV Cohort Study

Marzolini, C., Elzi, L., Gibbons, S., Weber, R., Fux, C., Furrer, H., . . . Battegay, M. (2010). Prevalence of comedications and effect of potential drug–drug interactions in the Swiss HIV Cohort Study. Antiviral Therapy, 15(3), 413-423. doi:10.3851/imp1540

DOI
10.3851/imp1540
Journal article

Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.

Elzi, L., Marzolini, C., Furrer, H., Ledergerber, B., Cavassini, M., Hirschel, B., . . . Swiss HIV Cohort Study. (2010). Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.. Archives of internal medicine, 170(1), 57-65. doi:10.1001/archinternmed.2009.432

DOI
10.1001/archinternmed.2009.432
Journal article

Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study.

Marzolini, C., Elzi, L., Gibbons, S., Weber, R., Fux, C., Furrer, H., . . . Swiss HIV Cohort Study. (2010). Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort Study.. Antiviral therapy, 15(3), 413-423. doi:10.3851/imp1540

DOI
10.3851/imp1540
Journal article

2009

Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus.

Mertz, D., Battegay, M., Marzolini, C., & Mayr, M. (2009). Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus.. American journal of kidney diseases : the official journal of the National Kidney Foundation, 54(1), e1-e4. doi:10.1053/j.ajkd.2009.01.268

DOI
10.1053/j.ajkd.2009.01.268
Journal article

2008

2007

A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression.

Marzolini, C., Tirona, R. G., Gervasini, G., Poonkuzhali, B., Assem, M., Lee, W., . . . Kim, R. B. (2007). A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression.. Molecular endocrinology (Baltimore, Md.), 21(8), 1769-1780. doi:10.1210/me.2007-0025

DOI
10.1210/me.2007-0025
Journal article

2006

Determination of the novel non-peptidic HIV-protease inhibitor tipranavir by HPLC-UV after solid-phase extraction.

Colombo, S., Béguin, A., Marzolini, C., Telenti, A., Biollaz, J., & Decosterd, L. A. (2006). Determination of the novel non-peptidic HIV-protease inhibitor tipranavir by HPLC-UV after solid-phase extraction.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 832(1), 138-143. doi:10.1016/j.jchromb.2005.11.040

DOI
10.1016/j.jchromb.2005.11.040
Journal article

Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study.

Ribaudo, H. J., Haas, D. W., Tierney, C., Kim, R. B., Wilkinson, G. R., Gulick, R. M., . . . Adult AIDS Clinical Trials Group Study. (2006). Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 42(3), 401-407. doi:10.1086/499364

DOI
10.1086/499364
Journal article

2005

Pharmacogenetics of Drug Transporters

Marzolini, C., Kim, R., & Tirona, R. (2005). Pharmacogenetics of Drug Transporters. In Drugs and the Pharmaceutical Sciences (pp. 109-155). CRC Press. doi:10.1201/9780849359507.ch5

DOI
10.1201/9780849359507.ch5
Chapter

Placental transfer of antiretroviral drugs.

Marzolini, C., & Kim, R. B. (2005). Placental transfer of antiretroviral drugs.. Clinical pharmacology and therapeutics, 78(2), 118-122. doi:10.1016/j.clpt.2005.05.002

DOI
10.1016/j.clpt.2005.05.002
Journal article

Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients.

Fellay, J., Marzolini, C., Decosterd, L., Golay, K. P., Baumann, P., Buclin, T., . . . Eap, C. B. (2005). Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients.. European journal of clinical pharmacology, 60(12), 865-873. doi:10.1007/s00228-004-0855-8

DOI
10.1007/s00228-004-0855-8
Journal article

2004

Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

Haas, D. W., Ribaudo, H. J., Kim, R. B., Tierney, C., Wilkinson, G. R., Gulick, R. M., . . . Acosta, E. P. (2004). Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.. AIDS (London, England), 18(18), 2391-2400.

Journal article

Determination of the new HIV-protease inhibitor atazanavir by liquid chromatography after solid-phase extraction

COLOMBO, S., GUIGNARD, N., MARZOLINI, C., TELENTI, A., BIOLLAZ, J., & DECOSTERD, L. (2004). Determination of the new HIV-protease inhibitor atazanavir by liquid chromatography after solid-phase extraction. Journal of Chromatography B, 810(1), 25-34. doi:10.1016/s1570-0232(04)00580-x

DOI
10.1016/s1570-0232(04)00580-x
Journal article

Determination of the new HIV-protease inhibitor atazanavir by liquid chromatography after solid-phase extraction.

Colombo, S., Guignard, N., Marzolini, C., Telenti, A., Biollaz, J., & Decosterd, L. A. (2004). Determination of the new HIV-protease inhibitor atazanavir by liquid chromatography after solid-phase extraction.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 810(1), 25-34. doi:10.1016/j.jchromb.2004.07.008

DOI
10.1016/j.jchromb.2004.07.008
Journal article

Population pharmacokinetics of indinavir in patients infected with human immunodeficiency virus.

Csajka, C., Marzolini, C., Fattinger, K., Décosterd, L. A., Telenti, A., Biollaz, J., & Buclin, T. (2004). Population pharmacokinetics of indinavir in patients infected with human immunodeficiency virus.. Antimicrobial agents and chemotherapy, 48(9), 3226-3232. doi:10.1128/aac.48.9.3226-3232.2004

DOI
10.1128/aac.48.9.3226-3232.2004
Journal article

Pharmacogenomics of the OATP and OAT families.

Marzolini, C., Tirona, R. G., & Kim, R. B. (2004). Pharmacogenomics of the OATP and OAT families.. Pharmacogenomics, 5(3), 273-282. doi:10.1517/phgs.5.3.273.29831

DOI
10.1517/phgs.5.3.273.29831
Journal article

MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment.

Bleiber, G., May, M., Suarez, C., Martinez, R., Marzolini, C., Egger, M., . . . Swiss HIV Cohort Study. (2004). MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment.. The Journal of infectious diseases, 189(4), 583-586. doi:10.1086/380134

DOI
10.1086/380134
Journal article

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance.

Marzolini, C., Paus, E., Buclin, T., & Kim, R. B. (2004). Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance.. Clinical pharmacology and therapeutics, 75(1), 13-33. doi:10.1016/j.clpt.2003.09.012

DOI
10.1016/j.clpt.2003.09.012
Journal article

2003

Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection.

Csajka, C., Marzolini, C., Fattinger, K., Décosterd, L. A., Fellay, J., Telenti, A., . . . Buclin, T. (2003). Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection.. Clinical pharmacology and therapeutics, 73(1), 20-30. doi:10.1067/mcp.2003.22

DOI
10.1067/mcp.2003.22
Journal article

2002

Efficacy and safety of fluvastatin in hyperlipidemic protease inhibitor-treated HIV-infected patients.

Doser, N., Kübli, S., Telenti, A., Marzolini, C., Chave, J. -P., Feihl, F., . . . Mooser, V. (2002). Efficacy and safety of fluvastatin in hyperlipidemic protease inhibitor-treated HIV-infected patients.. AIDS (London, England), 16(14), 1982-1983. doi:10.1097/00002030-200209270-00024

DOI
10.1097/00002030-200209270-00024
Journal article

Determination of lopinavir and nevirapine by high-performance liquid chromatography after solid-phase extraction: application for the assessment of their transplacental passage at delivery.

Marzolini, C., Béguin, A., Telenti, A., Schreyer, A., Buclin, T., Biollaz, J., & Decosterd, L. A. (2002). Determination of lopinavir and nevirapine by high-performance liquid chromatography after solid-phase extraction: application for the assessment of their transplacental passage at delivery.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 774(2), 127-140. doi:10.1016/s1570-0232(02)00169-1

DOI
10.1016/s1570-0232(02)00169-1
Journal article

Transplacental passage of protease inhibitors at delivery.

Marzolini, C., Rudin, C., Decosterd, L. A., Telenti, A., Schreyer, A., Biollaz, J., . . . Swiss Mother + Child HIV Cohort Study. (2002). Transplacental passage of protease inhibitors at delivery.. AIDS (London, England), 16(6), 889-893. doi:10.1097/00002030-200204120-00008

DOI
10.1097/00002030-200204120-00008
Journal article

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

Fellay, J., Marzolini, C., Meaden, E. R., Back, D. J., Buclin, T., Chave, J. P., . . . Telenti, A. (2002). Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. LANCET, 359(9300), 30-36. doi:10.1016/S0140-6736(02)07276-8

DOI
10.1016/S0140-6736(02)07276-8
Journal article

2001

Rote of therapeutic drug monitoring for antiretrovirals in HIV-1 patients care

Marzolini, C., Decosterd, L. A., Buclin, T., Telenti, A., & Biollaz, J. (2001). Rote of therapeutic drug monitoring for antiretrovirals in HIV-1 patients care. Medecine et Hygiene, 59(2369), 2302-2305.

Journal article

Impaired absorption of rifabutin by concomitant administration of didanosine.

Marzolini, C., Chave, J. P., Telenti, A., Brenas-Chinchon, L., & Biollaz, J. (2001). Impaired absorption of rifabutin by concomitant administration of didanosine.. AIDS (London, England), 15(16), 2203-2204. doi:10.1097/00002030-200111090-00022

DOI
10.1097/00002030-200111090-00022
Journal article

Nelfinavir plasma levels under twice-daily and three-times-daily regimens: high interpatient and low intrapatient variability.

Marzolini, C., Buclin, T., Decosterd, L. A., Biollaz, J., & Telenti, A. (2001). Nelfinavir plasma levels under twice-daily and three-times-daily regimens: high interpatient and low intrapatient variability.. Therapeutic drug monitoring, 23(4), 394-398. doi:10.1097/00007691-200108000-00012

DOI
10.1097/00007691-200108000-00012
Journal article

`Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients'

Marzolini, C., Telenti, A., Decosterd, L., Biollaz, J., & Buclin, T. (2001). `Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients'. AIDS, 15(9), 1193-1194. doi:10.1097/00002030-200106150-00023

DOI
10.1097/00002030-200106150-00023
Journal article

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients.

Marzolini, C., Telenti, A., Decosterd, L. A., Greub, G., Biollaz, J., & Buclin, T. (2001). Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients.. AIDS (London, England), 15(1), 71-75. doi:10.1097/00002030-200101050-00011

DOI
10.1097/00002030-200101050-00011
Journal article

2000

Efavirenz decreases methadone blood concentrations.

Marzolini, C., Troillet, N., Telenti, A., Baumann, P., Decosterd, L. A., & Eap, C. B. (2000). Efavirenz decreases methadone blood concentrations.. AIDS (London, England), 14(9), 1291-1292. doi:10.1097/00002030-200006160-00036

DOI
10.1097/00002030-200006160-00036
Journal article

Simultaneous determination of the HIV protease inhibitors indinavir, amprenavir, saquinavir, ritonavir, nelfinavir and the non-nucleoside reverse transcriptase inhibitor efavirenz by high-performance liquid chromatography after solid-phase extraction.

Marzolini, C., Telenti, A., Buclin, T., Biollaz, J., & Decosterd, L. A. (2000). Simultaneous determination of the HIV protease inhibitors indinavir, amprenavir, saquinavir, ritonavir, nelfinavir and the non-nucleoside reverse transcriptase inhibitor efavirenz by high-performance liquid chromatography after solid-phase extraction.. Journal of chromatography. B, Biomedical sciences and applications, 740(1), 43-58. doi:10.1016/s0378-4347(99)00573-3

DOI
10.1016/s0378-4347(99)00573-3
Journal article

1999

Erratum: Cancer Chemother Pharmacol (1998) 42: 433-440

Not Available, N. A. (1999). Erratum: Cancer Chemother Pharmacol (1998) 42: 433-440. Cancer Chemotherapy and Pharmacology, 43(5), 439-440. doi:10.1007/s002800050920

DOI
10.1007/s002800050920
Journal article

Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours.

Gander, M., Leyvraz, S., Decosterd, L., Bonfanti, M., Marzolini, C., Shen, F., . . . D'Incalci, M. (1999). Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours.. Annals of oncology : official journal of the European Society for Medical Oncology, 10(7), 831-838. doi:10.1023/a:1008304032421

DOI
10.1023/a:1008304032421
Journal article

1998

Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration.

Marzolini, C., Decosterd, L. A., Shen, F., Gander, M., Leyvraz, S., Bauer, J., . . . Lejeune, F. (1998). Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration.. Cancer chemotherapy and pharmacology, 42(6), 433-440. doi:10.1007/s002800050842

DOI
10.1007/s002800050842
Journal article