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Professor Carrol Gamble
BSc PhD

Contact

C.Gamble@liverpool.ac.uk

+44 (0)151 794 9759

Research

Research grants

Pilot-Education and training for recruiters to randomised trials

HEALTH RESEARCH BOARD (IRELAND)

January 2018 - December 2021

Extending ORRCA to create a central resource for retention research within clinical trials (ORRCA 2)

MEDICAL RESEARCH COUNCIL

June 2018 - November 2019

The Carboprost or Oxytocin Postpartum haemorrhage Effectiveness Study (COPE)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 2017 - November 2025

MIROR Methods in research on research

EUROPEAN COMMISSION

March 2016 - February 2020

From evidence to guidance on patient recruitment to clinical research in intensive care units.

ECONOMIC AND SOCIAL RESEARCH COUNCIL

September 2016 - May 2020

Methods for Patient and Public Involvement in Clinical Trials: A Research Priority and Agenda Setting Exercise.

MEDICAL RESEARCH COUNCIL

October 2015 - May 2017

TOPS: Timing of Primary Surgery for Cleft Palate (renewal)

NATIONAL INSTITUTES OF HEALTH (USA)

July 2016 - June 2021

The TRECA study: TRials Engagement in Children and Adolescents

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

February 2016 - July 2020

How does treatment with thyroxine for 6 weeks postnatally given to preterm infants born under 28 weeks gestation affect the hypothalamic-pituitary adrenal axix, somatic growth, meylination of white matter and the volumes of key brain structures? An exploratory randomised double blinded placebo controlled clinical trial

MEDICAL RESEARCH COUNCIL

March 2007 - May 2010

Development of an interactive website for outcome reporting bias research

MEDICAL RESEARCH COUNCIL

July 2015 - June 2016

Radiation versus observation following surgical resection of Atypical Meningioma: a randomised controlled trial (ROAM)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

November 2014 - March 2026

ORBIT II: Outcome Reporting Bias In Trials

MEDICAL RESEARCH COUNCIL

June 2012 - December 2013

SLEEPS: Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation: A Comparison of Clonidine and Midazolam

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

July 2007 - November 2012

Understanding the process and impact of within-study selective reporting bias.

MEDICAL RESEARCH COUNCIL

October 2006 - November 2008

Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

October 2012 - May 2015

Evaluation of Corticosteroid therapy in Childhood Severe Sepsis- a randomised pilot study

MENINGITIS RESEARCH FOUNDATION (UK)

October 2013 - June 2014

North West Hub for Trial Methodology Research (NWHTMR)

MEDICAL RESEARCH COUNCIL

October 2008 - August 2014

PREVAIL-Preventing infection using antibiotic impregnated long lines

DEPARTMENT OF HEALTH & SOCIAL CARE (UK), UNIVERSITY COLLEGE LONDON (UK)

June 2014 - August 2019

StePS study

MENINGITIS RESEARCH FOUNDATION (UK)

October 2007 - April 2013

A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic-clonic seizures including convulsive status epilepticus in children, the 'EcLIPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2014 - July 2019

Losing the losses: understanding the reasons for attrition in randomised trials and developing the evidence to prevent it

MEDICAL RESEARCH COUNCIL

October 2013 - July 2015

Onabotulinium toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial OVERT

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

July 2014 - August 2018

Healing Foundation Clinical Trials Unit

THE SCAR FREE FOUNDATION

June 2011 - September 2020

Establishing a database of statistical expertise to support clinical trial oversight committees and develop capacity

MEDICAL RESEARCH COUNCIL

April 2014 - September 2015

TP 165 feasilbility study of enhanced relapse prevention by key workers for people diagnosed with Bipolar Disorder.

MEDICAL RESEARCH COUNCIL

January 2005 - January 2007

The British Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts multi-centre randomised controlled trial (The BASICS trial)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2012 - February 2019

Training key workers to offer enhanced relapse prevention to people with bipolar disorder and their relatives within an NHS setting.

MERSEY CARE NHS FOUNDATION TRUST (UK)

September 2004 - August 2007

Trial steering committees for randomised controlled trials: Updating and redeveloping guidance and terms of reference, informed by current practice and experience

MEDICAL RESEARCH COUNCIL

October 2012 - September 2014

Clinical trial monitoring: establishing best UK practice?

MEDICAL RESEARCH COUNCIL

September 2011 - May 2013

MOMENT The management of otitis media with effusion (OME) in children with cleft palate

CENTRAL MANCHESTER TEACHING HOSPITALS (UK)

August 2012 - August 2013

Development of guidance for statistical analysis plans for clinical trials

MEDICAL RESEARCH COUNCIL

April 2014 - December 2016

Consolidating guidelines for the prevention, detection and appraisal of reporting biases in clinical trials

MEDICAL RESEARCH COUNCIL

May 2012 - October 2013

Medicines for Children Research Network Clinical Trials Unit

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2010 - March 2015

Development of a central resource for research in recruitment in clinical trials

MEDICAL RESEARCH COUNCIL

March 2014 - November 2018

Use of the electronic health record in the design and conduct of clinical trials

MEDICAL RESEARCH COUNCIL

November 2013 - September 2016

    Research collaborations

    Health Research Board Trials Methodology Research Network in Ireland

    Health Research Board Trials Methodology Research Network in Ireland, www.hrb-tmrn.ie – adding value to areas of common scientific interest and training;

    MRC Trials Methodology Research Partnership (TMRP)

    The TMRP brings together a number of networks, institutions and partners working in trials and trials methodology research.The TMRP builds on the achievements of the MRC Hubs for Trials Methodology Research Network to make continued progress in advancing trial methodology, developing capacity and further reducing research waste. https://www.methodologyhubs.mrc.ac.uk/about/tmrp/