Publications
2023
Prevalence of chronic pain or analgesic use in children and young people and its long-term impact on substance misuse, mental illness, and prescription opioid use: a retrospective longitudinal cohort study.
Lambarth, A., Katsoulis, M., Ju, C., Warwick, A., Takhar, R., Dale, C., . . . Sofat, R. (2023). Prevalence of chronic pain or analgesic use in children and young people and its long-term impact on substance misuse, mental illness, and prescription opioid use: a retrospective longitudinal cohort study.. The Lancet regional health. Europe, 35, 100763. doi:10.1016/j.lanepe.2023.100763
Antipsychotic drug prescribing and mortality in people with dementia before and during the COVID-19 pandemic: a retrospective cohort study in Wales, UK
Schnier, C., McCarthy, A., Morales, D. R., Akbari, A., Sofat, R., Dale, C., . . . Wilkinson, T. (2023). Antipsychotic drug prescribing and mortality in people with dementia before and during the COVID-19 pandemic: a retrospective cohort study in Wales, UK. LANCET HEALTHY LONGEVITY, 4(8), E421-E430. Retrieved from https://www.webofscience.com/
The impact of the COVID-19 pandemic on cardiovascular disease prevention and management
Sofat, R. (2023). The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. Nature Medicine. doi:10.1038/s41591-022-02158-7
Chronic pain in youth and substance misuse, mental illness and long-term prescription opioid use in adulthood: A retrospective longitudinal cohort study
Lambarth, A., Ju, C., Warwick, A., Takhar, R., Dale, C., Morris, A., . . . Sofat, R. (2023). Chronic pain in youth and substance misuse, mental illness and long-term prescription opioid use in adulthood: A retrospective longitudinal cohort study. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 89(3), 1258-1260. Retrieved from https://www.webofscience.com/
Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study
Kuan, V., Denaxas, S., Patalay, P., Nitsch, D., Mathur, R., Gonzalez-Izquierdo, A., . . . MMTRC. (2023). Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study. LANCET DIGITAL HEALTH, 5(1), E16-E27. doi:10.1016/S2589-7500(22)00187-X
Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals.
Chung, S. -C., Providencia, R., Sofat, R., Pujades-Rodriguez, M., Torralbo, A., Fatemifar, G., . . . Denaxas, S. (2023). Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 19(1), 123-135. doi:10.1002/alz.12635
Missed routine cardiovascular treatments during the COVID-19 pandemic
Dale, C., Takhar, R., & Sofat, R. (2023). Missed routine cardiovascular treatments during the COVID-19 pandemic. NATURE MEDICINE, 29(1), 45-46. doi:10.1038/s41591-022-02166-7
Use of Sodium Valproate and Other Anti-Seizure Medications in England and Wales During the COVID-19 Pandemic: A Population-Level Analysis of 60 Million Individuals
2022
COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records.
Thygesen, J. H., Tomlinson, C., Hollings, S., Mizani, M. A., Handy, A., Akbari, A., . . . Longitudinal Health and Wellbeing COVID-19 National Core Study and the CVD-COVID-UK/COVID-IMPACT Consortium. (2022). COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records.. The Lancet. Digital health, 4(7), e542-e557. doi:10.1016/s2589-7500(22)00091-7
Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort
Handy, A., Banerjee, A., Wood, A. M., Dale, C., Sudlow, C. L. M., Tomlinson, C., . . . Consortium, C. V. D. C. O. V. I. D. U. K. (2022). Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort. HEART, 108(12), 923-+. doi:10.1136/heartjnl-2021-320325
2021
Association between sleep quality and type 2 diabetes at 20-year follow-up in the Southall and Brent REvisited (SABRE) cohort: a triethnic analysis.
Ong, Z. L., Chaturvedi, N., Tillin, T., Dale, C., & Garfield, V. (2021). Association between sleep quality and type 2 diabetes at 20-year follow-up in the Southall and Brent REvisited (SABRE) cohort: a triethnic analysis.. Journal of epidemiology and community health, 75(11), 1117-1122. doi:10.1136/jech-2020-215796
2020
Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants.
Borges, M. C., Schmidt, A. F., Jefferis, B., Wannamethee, S. G., Lawlor, D. A., Kivimaki, M., . . . UCLEB Consortium**. (2020). Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants.. Journal of the American Heart Association, 9(5), e013131. doi:10.1161/jaha.119.013131
2019
The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.
Yu, B., Zanetti, K. A., Temprosa, M., Albanes, D., Appel, N., Barrera, C. B., . . . Moore, S. C. (2019). The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.. American journal of epidemiology, 188(6), 991-1012. doi:10.1093/aje/kwz028
The relationship between sleep duration, cognition and dementia: a Mendelian randomization study.
Henry, A., Katsoulis, M., Masi, S., Fatemifar, G., Denaxas, S., Acosta, D., . . . Dale, C. E. (2019). The relationship between sleep duration, cognition and dementia: a Mendelian randomization study.. International journal of epidemiology, 48(3), 849-860. doi:10.1093/ije/dyz071
Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals.
Garfield, V., Fatemifar, G., Dale, C., Smart, M., Bao, Y., Llewellyn, C. H., . . . Kumari, M. (2019). Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals.. Genetic epidemiology, 43(2), 207-214. doi:10.1002/gepi.22174
2018
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Franceschini, N., Giambartolomei, C., de Vries, P. S., Finan, C., Bis, J. C., Huntley, R. P., . . . O'Donnell, C. J. (2018). GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.. Nature communications, 9(1), 5141. doi:10.1038/s41467-018-07340-5
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in <i>PCSK9</i>
2017
Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.
Dale, C. E., Fatemifar, G., Palmer, T. M., White, J., Prieto-Merino, D., Zabaneh, D., . . . Casas, J. P. (2017). Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.. Circulation, 135(24), 2373-2388. doi:10.1161/circulationaha.116.026560
Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.
Bell, S., Daskalopoulou, M., Rapsomaniki, E., George, J., Britton, A., Bobak, M., . . . Hemingway, H. (2017). Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.. BMJ (Clinical research ed.), 356, j909. doi:10.1136/bmj.j909
Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.
Holzinger, E. R., Verma, S. S., Moore, C. B., Hall, M., De, R., Gilbert-Diamond, D., . . . Ritchie, M. D. (2017). Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.. BioData mining, 10, 25. doi:10.1186/s13040-017-0145-5
2016
Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.
Nüesch, E., Dale, C., Palmer, T. M., White, J., Keating, B. J., van Iperen, E. P., . . . Casas, J. P. (2016). Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.. International journal of epidemiology, 45(6), 1927-1937. doi:10.1093/ije/dyv074
Marginal role for 53 common genetic variants in cardiovascular disease prediction.
Morris, R. W., Cooper, J. A., Shah, T., Wong, A., Drenos, F., Engmann, J., . . . UCLEB Consortium. (2016). Marginal role for 53 common genetic variants in cardiovascular disease prediction.. Heart (British Cardiac Society), 102(20), 1640-1647. doi:10.1136/heartjnl-2016-309298
The association between characteristics of fathering in infancy and depressive symptoms in adolescence: A UK birth cohort study.
Scourfield, J., Culpin, I., Gunnell, D., Dale, C., Joinson, C., Heron, J., & Collin, S. M. (2016). The association between characteristics of fathering in infancy and depressive symptoms in adolescence: A UK birth cohort study.. Child abuse & neglect, 58, 119-128. doi:10.1016/j.chiabu.2016.06.013
Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.
Jackson, V. E., Ntalla, I., Sayers, I., Morris, R., Whincup, P., Casas, J. -P., . . . Wain, L. V. (2016). Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.. Thorax, 71(6), 501-509. doi:10.1136/thoraxjnl-2015-207876
Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.
Drenos, F., Davey Smith, G., Ala-Korpela, M., Kettunen, J., Würtz, P., Soininen, P., . . . Timpson, N. J. (2016). Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.. Circulation. Cardiovascular genetics, 9(3), 231-239. doi:10.1161/circgenetics.115.001302
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.
White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., . . . UCLEB (University College London-London School of Hygiene & Tropical Medicine-Edinburgh-Bristol Consortium. (2016). Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.. The lancet. Diabetes & endocrinology, 4(4), 327-336. doi:10.1016/s2213-8587(15)00386-1
2015
Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium.
Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., . . . Sattar, N. (2015). Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium.. BMJ open, 5(8), e008808. doi:10.1136/bmjopen-2015-008808
Incident disability in older adults: prediction models based on two British prospective cohort studies.
Nüesch, E., Pablo, P., Dale, C. E., Prieto-Merino, D., Kumari, M., Bowling, A., . . . Casas, J. P. (2015). Incident disability in older adults: prediction models based on two British prospective cohort studies.. Age and ageing, 44(2), 275-282. doi:10.1093/ageing/afu159
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., . . . Sattar, N. (2015). HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.. Lancet (London, England), 385(9965), 351-361. doi:10.1016/s0140-6736(14)61183-1
Why do thin people have elevated all-cause mortality? Evidence on confounding and reverse causality in the association of adiposity and COPD from the British Women's Heart and Health Study.
Dale, C., Nüesch, E., Prieto-Merino, D., Choi, M., Amuzu, A., Ebrahim, S., . . . Davey-Smith, G. (2015). Why do thin people have elevated all-cause mortality? Evidence on confounding and reverse causality in the association of adiposity and COPD from the British Women's Heart and Health Study.. PloS one, 10(4), e0115446. doi:10.1371/journal.pone.0115446
2014
Social capital, mortality, cardiovascular events and cancer: a systematic review of prospective studies.
Choi, M., Mesa-Frias, M., Nuesch, E., Hargreaves, J., Prieto-Merino, D., Bowling, A., . . . Casas, J. P. (2014). Social capital, mortality, cardiovascular events and cancer: a systematic review of prospective studies.. International journal of epidemiology, 43(6), 1895-1920. doi:10.1093/ije/dyu212
Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers.
Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., . . . Sattar, N. (2014). Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers.. PLoS genetics, 10(12), e1004799. doi:10.1371/journal.pgen.1004799
Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits.
Silverwood, R. J., Holmes, M. V., Dale, C. E., Lawlor, D. A., Whittaker, J. C., Smith, G. D., . . . Alcohol-ADH1B Consortium. (2014). Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits.. International journal of epidemiology, 43(6), 1781-1790. doi:10.1093/ije/dyu187
Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium.
Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Gabrielsen, M. E., Skorpen, F., Marioni, R. E., . . . Munafò, M. R. (2014). Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium.. BMJ open, 4(10), e006141. doi:10.1136/bmjopen-2014-006141
Alcohol consumption and cognitive performance: a Mendelian randomization study.
Kumari, M., Holmes, M. V., Dale, C. E., Hubacek, J. A., Palmer, T. M., Pikhart, H., . . . Bobak, M. (2014). Alcohol consumption and cognitive performance: a Mendelian randomization study.. Addiction (Abingdon, England), 109(9), 1462-1471. doi:10.1111/add.12568
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.
Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., . . . InterAct Consortium. (2014). Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.. BMJ (Clinical research ed.), 349, g4164. doi:10.1136/bmj.g4164
2013
Effect of changes in moderate or vigorous physical activity on changes in health-related quality of life of elderly British women over seven years.
Choi, M., Prieto-Merino, D., Dale, C., Nüesch, E., Amuzu, A., Bowling, A., . . . Casas, J. P. (2013). Effect of changes in moderate or vigorous physical activity on changes in health-related quality of life of elderly British women over seven years.. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 22(8), 2011-2020. doi:10.1007/s11136-012-0332-2
Predictors of patterns of change in health-related quality of life in older women over 7 years: evidence from a prospective cohort study.
Dale, C. E., Bowling, A., Adamson, J., Kuper, H., Amuzu, A., Ebrahim, S., . . . Nüesch, E. (2013). Predictors of patterns of change in health-related quality of life in older women over 7 years: evidence from a prospective cohort study.. Age and ageing, 42(3), 312-318. doi:10.1093/ageing/aft029
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
Shah, T., Engmann, J., Dale, C., Shah, S., White, J., Giambartolomei, C., . . . UCLEB Consortium. (2013). Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.. PloS one, 8(8), e71345. doi:10.1371/journal.pone.0071345
2012
Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women's Heart and Health Study.
Nüesch, E., Dale, C. E., Amuzu, A., Kuper, H., Bowling, A., Ploubidis, G. B., . . . Casas, J. P. (2012). Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women's Heart and Health Study.. European journal of epidemiology, 27(8), 633-645. doi:10.1007/s10654-012-9706-6
Later life health in Europe: how important are country level influences?
Ploubidis, G. B., Dale, C., & Grundy, E. (2012). Later life health in Europe: how important are country level influences?. European journal of ageing, 9(1), 5-13. doi:10.1007/s10433-011-0215-3
Modelling the association of disability according to the WHO International Classification of Functioning, Disability and Health (ICF) with mortality in the British Women's Heart and Health Study.
Dale, C., Prieto-Merino, D., Kuper, H., Adamson, J., Bowling, A., Ebrahim, S., & Casas, J. P. (2012). Modelling the association of disability according to the WHO International Classification of Functioning, Disability and Health (ICF) with mortality in the British Women's Heart and Health Study.. Journal of epidemiology and community health, 66(2), 170-175. doi:10.1136/jech-2011-200078
2010
Re: "Alcohol consumption in young adults and incident hypertension: 20-year follow-up from the Coronary Artery Risk Development in Young Adults Study".
Leon, D. A., Pablo-Casas, J., Dale, C., Polikina, O., Tomkins, S., & McKee, M. (2010). Re: "Alcohol consumption in young adults and incident hypertension: 20-year follow-up from the Coronary Artery Risk Development in Young Adults Study".. American journal of epidemiology, 172(6), 743-746. doi:10.1093/aje/kwq235
The burden of alcohol drinking on co-workers in the Australian workplace.
Dale, C. E., & Livingston, M. J. (2010). The burden of alcohol drinking on co-workers in the Australian workplace.. The Medical journal of Australia, 193(3), 138-140. doi:10.5694/j.1326-5377.2010.tb03831.x
Undated
Investigating the Potential Anti-Viral Effects of Proton Pump Inhibitors on Influenza: Intention-to-Treat Trial Emulation Using Electronic Health Records
Dale, C., Takhar, R., Katsoulis, M., Kuan Po Ai, V., Chung, S. -C., Providencia, R., . . . Sofat, R. (n.d.). Investigating the Potential Anti-Viral Effects of Proton Pump Inhibitors on Influenza: Intention-to-Treat Trial Emulation Using Electronic Health Records.