Publications
2024
Titration of RAS alters senescent state and influences tumour initiation.
Chan, A. S. L., Zhu, H., Narita, M., Cassidy, L. D., Young, A. R. J., Bermejo-Rodriguez, C., . . . Narita, M. (2024). Titration of RAS alters senescent state and influences tumour initiation.. Nature. doi:10.1038/s41586-024-07797-z
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.
Bermejo-Rodriguez, C., Araos Henríquez, J., Caligiuri, G., Pinto Teles, S., Park, Y., Evans, A., . . . Perez-Mancera, P. A. (2024). Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.. Cancer research. doi:10.1158/0008-5472.can-23-3419
Chemotherapy Assessment in Advanced Multicellular 3D Models of Pancreatic Cancer: Unravelling the Importance of Spatiotemporal Mimicry of the Tumor Microenvironment
Gupta, P., Bermejo-Rodriguez, C., Kocher, H., Pérez-Mancera, P. A., & Velliou, E. G. (2024). Chemotherapy Assessment in Advanced Multicellular 3D Models of Pancreatic Cancer: Unravelling the Importance of Spatiotemporal Mimicry of the Tumor Microenvironment. Advanced Biology. doi:10.1002/adbi.202300580
2023
Titration of oncogenic RAS alters senescent state and influences tumour initiation
The role of microRNAs in the modulation of cancer-associated fibroblasts activity during pancreatic cancer pathogenesis
Barrera, L. N., Ridley, P. M., Bermejo-Rodriguez, C., Costello, E., & Perez-Mancera, P. A. (2023). The role of microRNAs in the modulation of cancer-associated fibroblasts activity during pancreatic cancer pathogenesis. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 79(1), 193-204. doi:10.1007/s13105-022-00899-0
2022
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence
Tomimatsu, K., Bihary, D., Olan, I., Parry, A. J., Schoenfelder, S., Chan, A. S. L., . . . Narita, M. (2022). Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. NATURE AGING, 2(1), 31-+. doi:10.1038/s43587-021-00147-y
2020
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence
2019
Targeted Cancer Cell Killing by Highly Selective miRNA-Triggered Activation of a Prokaryotic Toxin-Antitoxin System
Turnbull, A., Bermejo-Rodriguez, C., Preston, M. A., Garrido-Barros, M., Pimentel, B., & de la Cueva-Mendez, G. (2019). Targeted Cancer Cell Killing by Highly Selective miRNA-Triggered Activation of a Prokaryotic Toxin-Antitoxin System. ACS SYNTHETIC BIOLOGY, 8(8), 1730-1736. doi:10.1021/acssynbio.9b00172
Targeted cancer cell killing by highly selective miRNA-triggered activation of a prokaryotic toxin-antitoxin system
2017
Generation of Mouse Models of Cancer Using Transposon‐Mediated Approaches
Bermejo‐Rodríguez, C., & Pérez‐Mancera, P. A. (n.d.). Generation of Mouse Models of Cancer Using Transposon‐Mediated Approaches. In Unknown Book (pp. 1-11). Wiley. doi:10.1002/9780470015902.a0026891
2016
Repurposing a Prokaryotic Toxin-Antitoxin System for the Selective Killing of Oncogenically Stressed Human Cells
Preston, M. A., Pimentel, B., Bermejo-Rodriguez, C., Dionne, I., Turnbull, A., & de la Cueva-Mendez, G. (2016). Repurposing a Prokaryotic Toxin-Antitoxin System for the Selective Killing of Oncogenically Stressed Human Cells. ACS SYNTHETIC BIOLOGY, 5(7), 540-546. doi:10.1021/acssynbio.5b00096
Identification of novel signalling pathways dysregulated in pancreatic cancer-associated fibroblasts
Barrera, L., Lane, B., Brumskill, S., Oldfield, F., Lamond, R., Wilkinson, L., . . . Costello, E. (2016). Identification of novel signalling pathways dysregulated in pancreatic cancer-associated fibroblasts. Pancreatology, 16(3), S31. doi:10.1016/j.pan.2016.05.106
2015
Use of DNA transposons for functional genetic screens in mouse models of cancer
Bermejo-Rodriguez, C., & Perez-Mancera, P. A. (2015). Use of DNA transposons for functional genetic screens in mouse models of cancer. CURRENT OPINION IN BIOTECHNOLOGY, 35, 103-110. doi:10.1016/j.copbio.2015.05.005
Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53
Kirschner, K., Samarajiwa, S. A., Cairns, J. M., Menon, S., Perez-Mancera, P. A., Tomimatsu, K., . . . Narita, M. (2015). Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53. PLOS GENETICS, 11(3). doi:10.1371/journal.pgen.1005053
2014
Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in <i>Escherichia coli</i> cells
Pimentel, B., Nair, R., Bermejo-Rodriguez, C., Preston, M. A., Agu, C. A., Wang, X., . . . de la Cueva-Mendez, G. (2014). Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in <i>Escherichia coli</i> cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(7), 2734-2739. doi:10.1073/pnas.1308241111
Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells
Pimentel, B., Nair, R., Bermejo-Rodríguez, C., Preston, M. A., Agu, C. A., Wang, X., . . . De La Cueva-Méndez, G. (2014). Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells. Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2734-2739. doi:10.1073/pnas.1308241111
2011
Waardenburg syndrome (WS)
Vicente-Dueñas, C., Bermejo-Rodrîguez, C., Pérez-Caro, M., González-Herrero, I., Sánchez-Martîn, M., & Sánchez-Garcîa, I. (n.d.). Waardenburg syndrome (WS). Atlas of Genetics and Cytogenetics in Oncology and Haematology, (2). doi:10.4267/2042/38200
2009
Cancer induction by restriction of oncogene expression to the stem cell compartment
Perez-Caro, M., Cobaleda, C., Gonzalez-Herrero, I., Vicente-Duenas, C., Bermejo-Rodriguez, C., Sanchez-Beato, M., . . . Sanchez-Garcia, I. (2009). Cancer induction by restriction of oncogene expression to the stem cell compartment. EMBO JOURNAL, 28(1), 8-20. doi:10.1038/emboj.2008.253
2008
<i>FUS</i>-<i>DDIT3</i> Prevents the Development of Adipocytic Precursors in Liposarcoma by Repressing PPARγ and C/EBPα and Activating eIF4E
Perez-Mancera, P. A., Bermejo-Rodriguez, C., Sanchez-Martin, M., Abollo-Jimenez, F., Pintado, B., & Sanchez-Garcia, I. (2008). <i>FUS</i>-<i>DDIT3</i> Prevents the Development of Adipocytic Precursors in Liposarcoma by Repressing PPARγ and C/EBPα and Activating eIF4E. PLOS ONE, 3(7). doi:10.1371/journal.pone.0002569
Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2)
Perez-Caro, M., Bermejo-Rodriguez, C., Gonzalez-Herrero, I., Sanchez-Beato, M., Piris, M. A., & Sanchez-Garcia, I. (2008). Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2). BRITISH JOURNAL OF CANCER, 98(2), 480-488. doi:10.1038/sj.bjc.6604084
2007
Adipose tissue mass is modulated by <i>SLUG</i> (<i>SNAI2</i>)
Antonio Perez-Mancera, P., Bermejo-Rodriguez, C., Gonzalez-Herrero, I., Herranz, M., Flores, T., Jimenez, R., & Sanchez-Garcia, I. (2007). Adipose tissue mass is modulated by <i>SLUG</i> (<i>SNAI2</i>). HUMAN MOLECULAR GENETICS, 16(23), 2972-2986. doi:10.1093/hmg/ddm278
2006
Mouse cDNA microarray analysis uncovers Slug targets in mouse embryonic fibroblasts
Bermejo-Rodríguez, C., Pérez-Caro, M., Pérez-Mancera, P. A., Sánchez-Beato, M., Piris, M. A., & Sánchez-García, I. (2006). Mouse cDNA microarray analysis uncovers Slug targets in mouse embryonic fibroblasts. GENOMICS, 87(1), 113-118. doi:10.1016/j.ygeno.2005.09.014