Publications
2024
Anthropometric, Body Composition, and Nutritional Indicators with and without Nutritional Intervention during Nitisinone Therapy in Alkaptonuria.
Ranganath, L. R., Khedr, M., Milan, A. M., Davison, A. S., Hughes, A. T., Norman, B. P., . . . Imrich, R. (2024). Anthropometric, Body Composition, and Nutritional Indicators with and without Nutritional Intervention during Nitisinone Therapy in Alkaptonuria.. Nutrients, 16(16), 2722. doi:10.3390/nu16162722
Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria.
Norman, B. P., Sutherland, H., Wilson, P. J. M., Rutland, D. A., Milan, A. M., Hughes, A. T., . . . Ranganath, L. R. (2024). Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria.. Journal of inherited metabolic disease, 47(4), 664-673. doi:10.1002/jimd.12728
Identification of novel bone-resorption markers by osteoclasts<i>in vitro</i>and<i>in vivo</i>
2023
Bile is a route of excretion for homogentisic acid in alkaptonuria
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways
Haaike, C. -V., Brendan, N. P., Sven, V. L., Andrew, D. S., Lionel, M., Georges, C., . . . Joery, D. K. (2023). Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways. GENES & DISEASES, 10(5), 1759-1762. doi:10.1016/j.gendis.2022.11.013
Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial
Ooi, N., Cooper, I. R., Norman, B., Gallagher, J. A., Sireau, N., Bou-Gharios, G., . . . Savage, V. J. (2023). Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial. CELLS, 12(13). doi:10.3390/cells12131683
Increased prevalence of Parkinson's disease in alkaptonuria
Ranganath, L., Khedr, M., Milan, A. M., Davison, A. S., Norman, B. P., Janssen, M. C. H., . . . Gallagher, J. A. (2023). Increased prevalence of Parkinson's disease in alkaptonuria. JIMD Reports. doi:10.1002/jmd2.12367
Post-Transcriptional Regulatory Crosstalk between MicroRNAs and Canonical TGF-β/BMP Signalling Cascades on Osteoblast Lineage: A Comprehensive Review.
Loh, H. -Y., Norman, B. P., Lai, K. -S., Cheng, W. -H., Nik Abd Rahman, N. M. A., Mohamed Alitheen, N. B., & Osman, M. A. (2023). Post-Transcriptional Regulatory Crosstalk between MicroRNAs and Canonical TGF-β/BMP Signalling Cascades on Osteoblast Lineage: A Comprehensive Review.. International journal of molecular sciences, 24(7), 6423. doi:10.3390/ijms24076423
Alkaptonuria - Past, present and future.
Davison, A. S., & Norman, B. P. (2023). Alkaptonuria - Past, present and future.. In Unknown Book (Vol. 114, pp. 47-81). doi:10.1016/bs.acc.2023.02.005
2022
Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria
Norman, B. P., Davison, A. S., Hickton, B., Ross, G. A., Milan, A. M., Hughes, A. T., . . . Ranganath, L. R. (2022). Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria. METABOLITES, 12(10). doi:10.3390/metabo12100927
Revisiting Quantification of Phenylalanine/Tyrosine Flux in the Ochronotic Pathway during Long-Term Nitisinone Treatment of Alkaptonuria
Ranganath, L. R., Hughes, A. T., Davison, A. S., Khedr, M., Imrich, R., Rudebeck, M., . . . Milan, A. M. (2022). Revisiting Quantification of Phenylalanine/Tyrosine Flux in the Ochronotic Pathway during Long-Term Nitisinone Treatment of Alkaptonuria. METABOLITES, 12(10). doi:10.3390/metabo12100920
Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria
Ranganath, L. R., Milan, A. M., Hughes, A. T., Davison, A. S., Khedr, M., Norman, B. P., . . . Olsson, B. (2022). Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-20424-z
Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment
Ranganath, L. R., Milan, A. M., Hughes, A. T., Davison, A. S., Khedr, M., Imrich, R., . . . Gallagher, J. A. (2022). Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment. METABOLITES, 12(8). doi:10.3390/metabo12080772
Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism
Norman, B. P., Davison, A. S., Hughes, J. H., Sutherland, H., Wilson, P. J. M., Berry, N. G., . . . Gallagher, J. A. (2022). Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism. GENES & DISEASES, 9(4), 1129-1142. doi:10.1016/j.gendis.2021.02.007
Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria.
Ranganath, L. R., Hughes, A. T., Davison, A. S., Khedr, M., Olsson, B., Rudebeck, M., . . . Milan, A. M. (2022). Temporal adaptations in the phenylalanine/tyrosine pathway and related factors during nitisinone-induced tyrosinaemia in alkaptonuria.. Molecular genetics and metabolism, S1096-7192(22)00325-0. doi:10.1016/j.ymgme.2022.05.006
Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria
Davison, A. S., Norman, B. P., Sutherland, H., Milan, A. M., Gallagher, J. A., Jarvis, J. C., & Ranganath, L. R. (2022). Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria. METABOLITES, 12(6). doi:10.3390/metabo12060477
Metabolomic analysis of bone resorption in vitro provides new insights into osteoclastic action and reveals novel biomarkers
Norman, B., Dillon, J., Bou-Gharios, G., Ranganath, L., & Gallagher, J. (2022). Metabolomic analysis of bone resorption in vitro provides new insights into osteoclastic action and reveals novel biomarkers. Bone Reports, 16, 101401. doi:10.1016/j.bonr.2022.101401
Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria
Ranganath, L. R., Milan, A. M., Hughes, A. T., Davison, A. S., Khedr, M., Norman, B. P., . . . Olsson, B. (2022). Characterization of changes in the tyrosine pathway by 24-h profiling during nitisinone treatment in alkaptonuria. Molecular Genetics and Metabolism Reports, 30, 100846. doi:10.1016/j.ymgmr.2022.100846
Altered bone metabolism in the rare inherited disease alkaptonuria
Norman, B. P., Hughes, J. H., Sutherland, H., Wilson, P. J., Ranganath, L. R., Bou-Gharios, G., & Gallagher, J. A. (2022). Altered bone metabolism in the rare inherited disease alkaptonuria. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 103 (pp. A8-A9). Retrieved from https://www.webofscience.com/
Altered bone metabolism in the rare inherited disease alkaptonuria
Norman, B. P., Hughes, J. H., Sutherland, H., Wilson, P. J., Ranganath, L. R., Bou-Gharios, G., & Gallagher, J. A. (2022). Altered bone metabolism in the rare inherited disease alkaptonuria. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 103 (pp. A3). Retrieved from https://www.webofscience.com/
Comparing nitisinone 2 mg and 10 mg in the treatment of alkaptonuria-An approach using statistical modelling.
Ranganath, L. R., Milan, A. M., Hughes, A. T., Khedr, M., Norman, B. P., Alsbou, M., . . . Jackson, R. (2022). Comparing nitisinone 2 mg and 10 mg in the treatment of alkaptonuria-An approach using statistical modelling.. JIMD reports, 63(1), 80-92. doi:10.1002/jmd2.12261
2021
Predicting dying from lung cancer: Urine metabolites predict the last weeks and days of life.
Coyle, S., Chapman, E., Baker, J., Coleman, H., Norman, B., Hughes, D., . . . Probert, C. (2021). Predicting dying from lung cancer: Urine metabolites predict the last weeks and days of life.. In JOURNAL OF CLINICAL ONCOLOGY Vol. 39. doi:10.1200/JCO.2021.39.15_suppl.12030
2020
DEFINING CANDIDATE PARKINSON’S DISEASE GENES THROUGH THE ANALYSIS OF GENOME-WIDE HOMOZYGOSITY
Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial
Ranganath, L. R., Psarelli, E. E., Arnoux, J. -B., Braconi, D., Briggs, M., Broijersen, A., . . . Gallagher, J. A. (2020). Efficacy and safety of once-daily nitisinone for patients with alkaptonuria (SONIA 2): an international, multicentre, open-label, randomised controlled trial. The Lancet Diabetes and Endocrinology, 8(9), 762-772. doi:10.1016/S2213-8587(20)30228-X
Nitisinone causes acquired tyrosinosis in alkaptonuria
Khedr, M., Cooper, M. S., Hughes, A. T., Milan, A. M., Davison, A. S., Norman, B. P., . . . Ranganath, L. R. (2020). Nitisinone causes acquired tyrosinosis in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43(5), 1014-1023. doi:10.1002/jimd.12229
Impact of nitisinone treatment and discontinuation on the metabolome of wild type and hereditary tyrosinemia type 1 mice
Colemonts-Vroninks, H., Norman, B. P., Andrew, D., Neuckermans, J., Lionel, M., Anneleen, M., . . . De Kock, J. (2020). Impact of nitisinone treatment and discontinuation on the metabolome of wild type and hereditary tyrosinemia type 1 mice. Journal of Hepatology, 73, S540-S541. doi:10.1016/s0168-8278(20)31554-3
Innentitelbild: Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose (Angew. Chem. 29/2020)
Chow, W. Y., Norman, B. P., Roberts, N. B., Ranganath, L. R., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Innentitelbild: Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose (Angew. Chem. 29/2020). Angewandte Chemie, 132(29), 11770. doi:10.1002/ange.202005824
Inside Cover: Pigmentation Chemistry and Radical‐Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage (Angew. Chem. Int. Ed. 29/2020)
Chow, W. Y., Norman, B. P., Roberts, N. B., Ranganath, L. R., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Inside Cover: Pigmentation Chemistry and Radical‐Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage (Angew. Chem. Int. Ed. 29/2020). Angewandte Chemie International Edition, 59(29), 11674. doi:10.1002/anie.202005824
Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage
Chow, W. Y., Norman, B. P., Roberts, N. B., Ranganath, L. R., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 59(29), 11937-11942. doi:10.1002/anie.202000618
Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose
Chow, W. Y., Norman, B. P., Roberts, N. B., Ranganath, L. R., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose. Angewandte Chemie, 132(29), 12035-12040. doi:10.1002/ange.202000618
Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria
Ranganath, L. R., Milan, A. M., Hughes, A. T., Khedr, M., Davison, A. S., Shweihdi, E., . . . Gallagher, J. A. (2020). Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria. JOURNAL OF INHERITED METABOLIC DISEASE, 43(4), 737-747. doi:10.1002/jimd.12181
Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage
Chow, W. Y., Norman, B. P., Roberts, N., Ranganath, L., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage. doi:10.26434/chemrxiv.11590950
Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage
Chow, W. Y., Norman, B., Roberts, N., Ranganath, L., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage. doi:10.26434/chemrxiv.11590950.v2
Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage
Chow, W. Y., Norman, B. P., Roberts, N., Ranganath, L., Teutloff, C., Bittl, R., . . . Oschkinat, H. (2020). Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage. doi:10.26434/chemrxiv.11590950.v1
2019
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria
Hughes, J. H., Liu, K., Plagge, A., Wilson, P. J. M., Sutherland, H., Norman, B. P., . . . Bou-Gharios, G. (2019). Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria. Human Molecular Genetics, 28(23), 3928-3939. doi:10.1093/hmg/ddz234
The Regulatory Role of MicroRNAs in Breast Cancer
Loh, H. -Y., Norman, B. P., Lai, K. -S., Abd Rahman, N. M. A. N., Alitheen, N. B. M., & Osman, M. A. (2019). The Regulatory Role of MicroRNAs in Breast Cancer. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(19). doi:10.3390/ijms20194940
Biochemical Investigations in the Rare Disease Alkaptonuria: Studies on the Metabolome and the Nature of Ochronotic Pigment
Norman, B. (2019, September 30). Biochemical Investigations in the Rare Disease Alkaptonuria: Studies on the Metabolome and the Nature of Ochronotic Pigment.
Interference of hydroxyphenylpyruvic acid, hydroxyphenyllactic acid and tyrosine on routine serum and urine clinical chemistry assays; implications for biochemical monitoring of patients with alkaptonuria treated with nitisinone
Curtis, S. L., Norman, B. P., Milan, A. M., Gallagher, J. A., Olsson, B., Ranganath, L. R., & Roberts, N. B. (2019). Interference of hydroxyphenylpyruvic acid, hydroxyphenyllactic acid and tyrosine on routine serum and urine clinical chemistry assays; implications for biochemical monitoring of patients with alkaptonuria treated with nitisinone. CLINICAL BIOCHEMISTRY, 71, 24-30. doi:10.1016/j.clinbiochem.2019.06.010
Ochronotic pigmentation is caused by homogentisic acid and is the key event in alkaptonuria leading to the destructive consequences of the disease-A review
Ranganath, L. R., Norman, B. P., & Gallagher, J. A. (2019). Ochronotic pigmentation is caused by homogentisic acid and is the key event in alkaptonuria leading to the destructive consequences of the disease-A review. JOURNAL OF INHERITED METABOLIC DISEASE, 42(5), 776-792. doi:10.1002/jimd.12152
Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis
Taylor, A. M., Jenks, D. D., Kammath, V. D., Norman, B. P., Dillon, J. P., Gallagher, J. A., . . . Kerns, J. G. (2019). Raman Spectroscopy identifies differences in ochronotic and non-ochronotic cartilage; a potential novel technique for monitoring ochronosis. OSTEOARTHRITIS AND CARTILAGE, 27(8), 1244-1251. doi:10.1016/j.joca.2019.04.012
Evaluation of the serum metabolome of patients with alkaptonuria before and after two years of treatment with nitisinone using LC-QTOF-MS.
Davison, A. S., Norman, B. P., Ross, G. A., Hughes, A. T., Khedr, M., Milan, A. M., . . . Ranganath, L. R. (2019). Evaluation of the serum metabolome of patients with alkaptonuria before and after two years of treatment with nitisinone using LC-QTOF-MS.. JIMD reports, 48(1), 67-74. doi:10.1002/jmd2.12042
EXTRACELLULAR CHEMICAL PROFILING BY LC-QTOF-MS IDENTIFIES NOVEL BONE RESORPTION MARKERS FOR MONITORING PROGRESSION OF OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA
Norman, B. P., Dillon, J. P., Wilson, P. J., Davison, A. S., Milan, A. M., Ross, G. R., . . . Gallagher, J. A. (2019). EXTRACELLULAR CHEMICAL PROFILING BY LC-QTOF-MS IDENTIFIES NOVEL BONE RESORPTION MARKERS FOR MONITORING PROGRESSION OF OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA. In OSTEOARTHRITIS AND CARTILAGE Vol. 27 (pp. S181-S182). doi:10.1016/j.joca.2019.02.274
A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria.
Norman, B. P., Davison, A. S., Ross, G. A., Milan, A. M., Hughes, A. T., Sutherland, H., . . . Ranganath, L. R. (2019). A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria.. Clinical chemistry. doi:10.1373/clinchem.2018.295345
Untargeted extracellular chemical profiling by LC-QTOF-MS identifies novel markers of bone collagen degradation
Norman, B. P., Dillon, J. P., Nzenwa, I., Wilson, P. J., Davison, A. S., Milan, A. M., . . . Gallagher, J. A. (2019). Untargeted extracellular chemical profiling by LC-QTOF-MS identifies novel markers of bone collagen degradation. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A29). Retrieved from https://www.webofscience.com/
2018
Comprehensive targeted LC-QTOF-MS metabolomics identifies novel metabolite changes associated with treatment of the rare bone disease Alkaptonuria
Norman, B., Davison, A., Ross, G., Milan, A., Hughes, A., Roberts, N., . . . Gallagher, J. (2018). Comprehensive targeted LC-QTOF-MS metabolomics identifies novel metabolite changes associated with treatment of the rare bone disease Alkaptonuria. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 33 (pp. 145). Retrieved from http://gateway.webofknowledge.com/
Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone
Davison, A. S., Harrold, J. A., Hughes, G., Norman, B., Devine, J., Usher, J., . . . Ranganath, L. R. (2018). Clinical and biochemical assessment of depressive symptoms in patients with Alkaptonuria before and after two years of treatment with nitisinone. Molecular Genetics and Metabolism, 125(1-2), 135-143. doi:10.1016/j.ymgme.2018.07.008
COMBINED LC-QTOF-MS URINE METABOLOMICS AND 18F-NAF PET IMAGING INDICATES NOVEL COMPOUNDS ASSOCIATED WITH SPINE OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA
Norman, B. P., Taylor, L. F., Davison, A. S., Milan, A. M., Ross, G. A., Roberts, N. B., . . . Gallagher, J. A. (2018). COMBINED LC-QTOF-MS URINE METABOLOMICS AND 18F-NAF PET IMAGING INDICATES NOVEL COMPOUNDS ASSOCIATED WITH SPINE OSTEOARTHROPATHY IN THE RARE DISEASE ALKAPTONURIA. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S170). doi:10.1016/j.joca.2018.02.369
DISRUPTION OF COLLAGEN TRIPLE HELIX HYDROGEN BONDING IN OCHRONOTIC HUMAN CARTILAGE IN ALKAPTONURIA OBSERVED BY DYNAMIC NUCLEAR POLARISATION-ENHANCED SOLID-STATE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Norman, B. P., Ying, C. W., Sutherland, H., Wilson, P. J., Roberts, N. B., Duer, M. J., . . . Gallagher, J. A. (2018). DISRUPTION OF COLLAGEN TRIPLE HELIX HYDROGEN BONDING IN OCHRONOTIC HUMAN CARTILAGE IN ALKAPTONURIA OBSERVED BY DYNAMIC NUCLEAR POLARISATION-ENHANCED SOLID-STATE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S99). doi:10.1016/j.joca.2018.02.214
RAMAN SPECTROSCOPY CAN NON-INVASIVELY DISTINGUISH BETWEEN OCHRONOTIC AND NON-OCHRONOTIC CARTILAGE
Taylor, A. M., Jenks, D., Kammath, V. D., Norman, B., Dillon, J. P., Gallagher, J. A., . . . Kerns, J. G. (2018). RAMAN SPECTROSCOPY CAN NON-INVASIVELY DISTINGUISH BETWEEN OCHRONOTIC AND NON-OCHRONOTIC CARTILAGE. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S105). doi:10.1016/j.joca.2018.02.227
Assessment of the Effect of Once Daily Nitisinone Therapy on 24-h Urinary Metadrenalines and 5-Hydroxyindole Acetic Acid Excretion in Patients with Alkaptonuria After 4 Weeks of Treatment
Davison, A. S., Norman, B., Milan, A. M., Hughes, A. T., Khedr, M., Rovensky, J., . . . Ranganath, L. R. (2018). Assessment of the Effect of Once Daily Nitisinone Therapy on 24-h Urinary Metadrenalines and 5-Hydroxyindole Acetic Acid Excretion in Patients with Alkaptonuria After 4 Weeks of Treatment. JIMD REPORTS: FOCUS ISSUE: ADULTS AND METABOLISM, VOL 41, 41, 1-10. doi:10.1007/8904_2017_72
Serum Amino Acid Profiling in Patients with Alkaptonuria Before and After Treatment with Nitisinone
Davison, A. S., Norman, B. P., Smith, E. A., Devine, J., Usher, J., Hughes, A. T., . . . Ranganath, L. R. (2018). Serum Amino Acid Profiling in Patients with Alkaptonuria Before and After Treatment with Nitisinone. JIMD REPORTS: FOCUS ISSUE: ADULTS AND METABOLISM, VOL 41, 41, 109-117. doi:10.1007/8904_2018_109
2017
Early Onset Parkinson's Disease in a family of Moroccan origin caused by a p.A217D mutation in <i>PINK1</i>: a case report
Norman, B. P., Lubbe, S. J., Tan, M., Warren, N., & Morris, H. R. (2017). Early Onset Parkinson's Disease in a family of Moroccan origin caused by a p.A217D mutation in <i>PINK1</i>: a case report. BMC NEUROLOGY, 17. doi:10.1186/s12883-017-0933-z
URINE METABOLOMICS USING LIQUID CHROMATOGRAPHY QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY INDICATES COMMON MARKERS OF DISEASE IN ALKAPTONURIA AND IDIOPATHIC OSTEOARTHRITIS IN HUMAN
Norman, B., Davison, A., Wilson, P., Ross, G., Milan, A., Roberts, N., . . . Gallagher, J. (2017). URINE METABOLOMICS USING LIQUID CHROMATOGRAPHY QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY INDICATES COMMON MARKERS OF DISEASE IN ALKAPTONURIA AND IDIOPATHIC OSTEOARTHRITIS IN HUMAN. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S97-S98). doi:10.1016/j.joca.2017.02.156
2014
Are mobile phone conversations always so annoying? The 'need-to-listen' effect re-visited
Norman, B., & Bennett, D. (2014). Are mobile phone conversations always so annoying? The 'need-to-listen' effect re-visited. BEHAVIOUR & INFORMATION TECHNOLOGY, 33(12), 1294-1305. doi:10.1080/0144929X.2013.876098