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2024

2023

Umbilical cord mesenchymal stromal cell-derived extracellular vesicles lack the potency to immunomodulate human monocyte-derived macrophages in vitro.

da Silva, T. B., Rendra, E., David, C. A. W., Bieback, K., Cross, M. J., Wilm, B., . . . Murray, P. (2023). Umbilical cord mesenchymal stromal cell-derived extracellular vesicles lack the potency to immunomodulate human monocyte-derived macrophages in vitro.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 167, 115624. doi:10.1016/j.biopha.2023.115624

DOI
10.1016/j.biopha.2023.115624
Journal article

Mesothelial cells exhibit characteristics of perivascular cells in an<i>in vitro</i>angiogenesis assay

DOI
10.1101/2023.08.11.552910
Preprint

Harmonised culture procedures minimise but do not eliminate mesenchymal stromal cell donor and tissue variability in a decentralised multicentre manufacturing approach

Calcat-i-Cervera, S., Rendra, E., Scaccia, E., Amadeo, F., Hanson, V., Wilm, B., . . . Bieback, K. (2023). Harmonised culture procedures minimise but do not eliminate mesenchymal stromal cell donor and tissue variability in a decentralised multicentre manufacturing approach. STEM CELL RESEARCH & THERAPY, 14(1). doi:10.1186/s13287-023-03352-1

DOI
10.1186/s13287-023-03352-1
Journal article

Deep learning-based evaluation of a mouse model of kidney ischaemia reperfusion injury: classification and segmentation approaches

Luchian, A., Trivino-Cepeda, K., Murray, P., Wilm, B., & Ressel, L. (2023). Deep learning-based evaluation of a mouse model of kidney ischaemia reperfusion injury: classification and segmentation approaches. Journal of Comparative Pathology, 203, 68. doi:10.1016/j.jcpa.2023.03.096

DOI
10.1016/j.jcpa.2023.03.096
Journal article

VEGF Stimulates Activation of ERK5 in the Absence of C-Terminal Phosphorylation Preventing Nuclear Localization and Facilitating AKT Activation in Endothelial Cells

Mondru, A. K., Aljasir, M. A., Alrumayh, A., Nithianandarajah, G. N., Ahmed, K., Muller, J., . . . Cross, M. J. (2023). VEGF Stimulates Activation of ERK5 in the Absence of C-Terminal Phosphorylation Preventing Nuclear Localization and Facilitating AKT Activation in Endothelial Cells. CELLS, 12(6). doi:10.3390/cells12060967

DOI
10.3390/cells12060967
Journal article

Harmonised culture procedures minimise but not eliminate mesenchymal stromal cell donor and tissue variability in a decentralized multicentre manufacturing approach

DOI
10.21203/rs.3.rs-2321328/v1
Preprint

Near infrared conjugated polymer nanoparticles (CPN™) for tracking cells using fluorescence and optoacoustic imaging

DOI
10.1101/2023.01.30.526261
Preprint

2022

Optical Tissue Clearing to Study the Intra-Pulmonary Biodistribution of Intravenously Delivered Mesenchymal Stromal Cells and Their Interactions with Host Lung Cells

Pichardo, A. H., Amadeo, F., Wilm, B., Lévy, R., Ressel, L., Murray, P., & Sée, V. (n.d.). Optical Tissue Clearing to Study the Intra-Pulmonary Biodistribution of Intravenously Delivered Mesenchymal Stromal Cells and Their Interactions with Host Lung Cells. International Journal of Molecular Sciences, 23(22), 14171. doi:10.3390/ijms232214171

DOI
10.3390/ijms232214171
Journal article

Intravenous administration of human umbilical cord mesenchymal stromal cells leads to an inflammatory response in the lung

DOI
10.1101/2022.09.26.509547
Preprint

The transition zone in Hirschsprung’s bowel contains abnormal hybrid ganglia with characteristics of extrinsic nerves

DOI
10.1101/2022.06.15.22276240
Preprint

2021

2020

G324 Expression of neurones and neuronal precursors in the transition zone of short segment hirschsprung’s disease

Doherty, J., Chhabra, S., Smith, M., Edgar, D., Almond, S., Kenny, S. E., & Wilm, B. (2020). G324 Expression of neurones and neuronal precursors in the transition zone of short segment hirschsprung’s disease. In British association for paediatric nephrology (pp. A117.3-A117). BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2020-rcpch.280

DOI
10.1136/archdischild-2020-rcpch.280
Conference Paper

Restricted differentiative capacity of Wt1-expressing peritoneal mesothelium in postnatal and adult mice

DOI
10.1101/2020.08.21.257154
Preprint

Multimodal Imaging Techniques Show Differences in Homing Capacity Between Mesenchymal Stromal Cells and Macrophages in Mouse Renal Injury Models

Taylor, A., Sharkey, J., Harwood, R., Scarfe, L., Barrow, M., Rosseinsky, M. J., . . . Murray, P. (2020). Multimodal Imaging Techniques Show Differences in Homing Capacity Between Mesenchymal Stromal Cells and Macrophages in Mouse Renal Injury Models. MOLECULAR IMAGING AND BIOLOGY, 22(4), 904-913. doi:10.1007/s11307-019-01458-8

DOI
10.1007/s11307-019-01458-8
Journal article

2019

A Noninvasive Imaging Toolbox Indicates Limited Therapeutic Potential of Conditionally Activated Macrophages in a Mouse Model of Multiple Organ Dysfunction

Sharkey, J., Ressel, L., Brillant, N., Scarfe, L., Wilm, B., Park, B. K., & Murray, P. (2019). A Noninvasive Imaging Toolbox Indicates Limited Therapeutic Potential of Conditionally Activated Macrophages in a Mouse Model of Multiple Organ Dysfunction. Stem Cells International, 2019. doi:10.1155/2019/7386954

DOI
10.1155/2019/7386954
Journal article

2018

In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells

Ashraf, S., Taylor, A., Sharkey, J., Barrow, M., Murray, P., Wilm, B., . . . Levy, R. (2018). In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells. Nanoscale Advances. doi:10.1039/C8NA00098K

DOI
10.1039/C8NA00098K
Journal article

Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells in Vivo (vol 10, pg 7106, 2016)

Comenge, J., Fragueiro, O., Sharkey, J., Taylor, A., Held, M., Burton, N. C., . . . Levy, R. (2018). Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells <i>in Vivo</i> (vol 10, pg 7106, 2016). ACS NANO, 12(8), 8831. doi:10.1021/acsnano.8b05577

DOI
10.1021/acsnano.8b05577
Journal article

<i>In vivo</i> fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells

DOI
10.1101/366518
Preprint

Development of an imaging toolbox to assess the therapeutic potential and biodistribution of macrophages in a mouse model of multiple organ dysfunction

DOI
10.1101/372482
Preprint

2017

Non-invasive imaging reveals conditions that impact distribution and persistence of cells after in vivo administration.

Scarfe, L., Taylor, A., Sharkey, J., Harwood, R., Barrow, M., Comenge, J., . . . Wilm, B. (2018). Non-invasive imaging reveals conditions that impact distribution and persistence of cells after in vivo administration. STEM CELL RESEARCH & THERAPY, 9. doi:10.1186/s13287-018-1076-x

DOI
10.1186/s13287-018-1076-x
Journal article

Utilising multispectral optoacoustic tomography (MSOT) to assess organ function and track labelled therapeutic cells for regenerative medicine therapies in vivo

Sharkey, J., Scarfe, L., Comenge, J., Brillant, N., Burton, N., Antoine, D., . . . Murray, P. (2017). Utilising multispectral optoacoustic tomography (MSOT) to assess organ function and track labelled therapeutic cells for regenerative medicine therapies in vivo. HUMAN GENE THERAPY, 28(8), A19. Retrieved from https://www.webofscience.com/

Journal article

Nephron Progenitors

Santeramo, I., Wilm, B., & Murray, P. (2017). Nephron Progenitors. In KIDNEY TRANSPLANTATION, BIOENGINEERING, AND REGENERATION: KIDNEY TRANSPLANTATION IN THE REGENERATIVE MEDICINE ERA (pp. 1053-1065). doi:10.1016/B978-0-12-801734-0.00076-X

DOI
10.1016/B978-0-12-801734-0.00076-X
Chapter

Optimising the use of medicines to reduce acute kidney injury in children and babies

Oni, L., Hawcutt, D. B., Turner, M. A., Beresford, M. W., McWilliam, S., Barton, C., . . . Antoine, D. J. (2017). Optimising the use of medicines to reduce acute kidney injury in children and babies. Pharmacology and Therapeutics, 174, 55-62. doi:10.1016/j.pharmthera.2017.02.018

DOI
10.1016/j.pharmthera.2017.02.018
Journal article

Chapter 76 Nephron Progenitors

Santeramo, I., Wilm, B., & Murray, P. (2017). Chapter 76 Nephron Progenitors. In Kidney Transplantation, Bioengineering and Regeneration (pp. 1053-1065). Elsevier. doi:10.1016/b978-0-12-801734-0.00076-x

DOI
10.1016/b978-0-12-801734-0.00076-x
Chapter

Multimodal stem cell imaging and tracking

Ashraf, S., Barrow, M., Comenge, J., Taylor, A., Sharkey, J., Murray, P., . . . Levy, R. (2017). Multimodal stem cell imaging and tracking. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 254. Retrieved from https://www.webofscience.com/

Conference Paper

2016

Imaging technologies for monitoring the safety, efficacy and mechanisms of action of cell-based regenerative medicine therapies in models of kidney disease

Sharkey, J., Scarfe, L., Santeramo, I., Garcia-Finana, M., Park, B. K., Poptani, H., . . . Murray, P. (2016). Imaging technologies for monitoring the safety, efficacy and mechanisms of action of cell-based regenerative medicine therapies in models of kidney disease. EUROPEAN JOURNAL OF PHARMACOLOGY, 790, 74-82. doi:10.1016/j.ejphar.2016.06.056

DOI
10.1016/j.ejphar.2016.06.056
Journal article

INTEGRATING NOVEL IMAGING TECHNOLOGIES TO INVESTIGATE DRUG-INDUCED KIDNEY TOXICITY

Wilm, B., & Burton, N. C. (2016). INTEGRATING NOVEL IMAGING TECHNOLOGIES TO INVESTIGATE DRUG-INDUCED KIDNEY TOXICITY. In DRUG DISCOVERY TOXICOLOGY: FROM TARGET ASSESSMENT TO TRANSLATIONAL BIOMARKERS (pp. 454-457). Retrieved from https://www.webofscience.com/

Chapter

2015

Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy

Scarfe, L., Rak-Raszewska, A., Geraci, S., Darssan, D., Sharkey, J., Huang, J., . . . Wilm, B. (2015). Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy. Scientific Reports, 5. doi:10.1038/srep13601

DOI
10.1038/srep13601
Journal article

2014

The role of ERK5 in endothelial cell function

Nithianandarajah-Jones, G. N., Wilm, B., Goldring, C. E. P., Mueller, J., & Cross, M. J. (2014). The role of ERK5 in endothelial cell function. BIOCHEMICAL SOCIETY TRANSACTIONS, 42, 1584-1589. doi:10.1042/BST20140276

DOI
10.1042/BST20140276
Journal article

2013

Correction: Stem Cells Derived from Neonatal Mouse Kidney Generate Functional Proximal Tubule-Like Cells and Integrate into Developing Nephrons In Vitro

Ranghini, E., Mora, C. F., Edgar, D., Kenny, S. E., Murray, P., & Wilm, B. (n.d.). Correction: Stem Cells Derived from Neonatal Mouse Kidney Generate Functional Proximal Tubule-Like Cells and Integrate into Developing Nephrons In Vitro. PLoS ONE, 8(6). doi:10.1371/annotation/57bd3cdf-4d63-41a6-972a-904e00c369ad

DOI
10.1371/annotation/57bd3cdf-4d63-41a6-972a-904e00c369ad
Journal article

Regulation of Progenitor Cell Proliferation and Neuronal Differentiation in Enteric Nervous System Neurospheres

Theocharatos, S., Wilkinson, D. J., Darling, S., Wilm, B., Kenny, S. E., & Edgar, D. (2013). Regulation of Progenitor Cell Proliferation and Neuronal Differentiation in Enteric Nervous System Neurospheres. PLOS ONE, 8(1). doi:10.1371/journal.pone.0054809

DOI
10.1371/journal.pone.0054809
Journal article

2012

ERK5: Structure, regulation and function

Nithianandarajah-Jones, G. N., Wilm, B., Goldring, C. E. P., Mueller, J., & Cross, M. J. (2012). ERK5: Structure, regulation and function. CELLULAR SIGNALLING, 24(11), 2187-2196. doi:10.1016/j.cellsig.2012.07.007

DOI
10.1016/j.cellsig.2012.07.007
Journal article

Development of embryonic stem cells in recombinant kidneys

Rak-Raszewska, A., Wilm, B., Edgar, D., Kenny, S., Woolf, A. S., & Murray, P. (2012). Development of embryonic stem cells in recombinant kidneys. ORGANOGENESIS, 8(4), 125-136. doi:10.4161/org.22597

DOI
10.4161/org.22597
Journal article

Integration potential of mouse and human bone marrow-derived mesenchymal stem cells

Kuzma-Kuzniarska, M., Rak-Raszewska, A., Kenny, S., Edgar, D., Wilm, B., Mora, C. F., . . . Murray, P. (2012). Integration potential of mouse and human bone marrow-derived mesenchymal stem cells. DIFFERENTIATION, 83(3), 128-137. doi:10.1016/j.diff.2011.11.004

DOI
10.1016/j.diff.2011.11.004
Journal article

Differentiation of Podocyte and Proximal Tubule-Like Cells from a Mouse Kidney-Derived Stem Cell Line

Mora, C. F., Ranghini, E., Bruno, S., Bussolati, B., Camussi, G., Wilm, B., . . . Murray, P. (2012). Differentiation of Podocyte and Proximal Tubule-Like Cells from a Mouse Kidney-Derived Stem Cell Line. STEM CELLS AND DEVELOPMENT, 21(2), 296-307. doi:10.1089/scd.2010.0470

DOI
10.1089/scd.2010.0470
Journal article

2011

2 Characterising the progenitor cell potential of adult mesothelial cells

Cash, N., Nithianandarajah, G., & Wilm, B. (2011). 2 Characterising the progenitor cell potential of adult mesothelial cells. Heart, 97(20), e7. doi:10.1136/heartjnl-2011-300920b.2

DOI
10.1136/heartjnl-2011-300920b.2
Journal article

Integration potential of mouse and human bone marrow-derived mesenchymal stem cells

Kuzma-Kuzniarska, M., Rak-Raszewska, A., Kenny, S., Edgar, D., Wilm, B., Fuente, M. C., . . . Murray, P. (2011). Integration potential of mouse and human bone marrow-derived mesenchymal stem cells. Differentiation, 83, 128-137.

Journal article

2010

The potential of small chemical functional groups for directing the differentiation of kidney stem cells

Murray, P., Vasilev, K., Mora, C. F., Ranghini, E., Tensaout, H., Rak-Raszewska, A., . . . Kenny, S. E. (2010). The potential of small chemical functional groups for directing the differentiation of kidney stem cells. BIOCHEMICAL SOCIETY TRANSACTIONS, 38, 1062-1066. doi:10.1042/BST0381062

DOI
10.1042/BST0381062
Journal article

A report of the first international WT1 meeting, University of Manchester UK, 2008.

Wilm, B., & Ladomery, M. R. (2010). A report of the first international WT1 meeting, University of Manchester UK, 2008.. International journal of molecular epidemiology and genetics, 1(1), 76-82.

Journal article

The potential of small chemical functional groups for directing the differentiation of kidney stem cells

Murray, P., Vasilev, K., Mora Fuente, C., Ranghini, E., Tensaout, H., Rak-Raszewska, A., . . . Kenny, S. E. (2010). The potential of small chemical functional groups for directing the differentiation of kidney stem cells. Biochem Soc Trans., 38(4), 1062-1066.

Journal article

2008

Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development

Que, J., Wilm, B., Hasegawa, H., Wang, F., Bader, D., & Hogan, B. L. M. (2008). Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(43), 16626-16630. doi:10.1073/pnas.0808649105

DOI
10.1073/pnas.0808649105
Journal article

Serosal mesothelium retains vasculogenic potential (vol 236, pg 2973, 2007)

Kawaguchi, M., Bader, D. M., & Wilm, B. (2008). Serosal mesothelium retains vasculogenic potential (vol 236, pg 2973, 2007). DEVELOPMENTAL DYNAMICS, 237(2), 525. doi:10.1002/dvdy.21443

DOI
10.1002/dvdy.21443
Journal article

2007

Serosal mesothelium retains vasculogenic potential

Kawaguchi, M., Bader, D. M., & Wilm, B. (2007). Serosal mesothelium retains vasculogenic potential. DEVELOPMENTAL DYNAMICS, 236(11), 2973-2979. doi:10.1002/dvdy.21334

DOI
10.1002/dvdy.21334
Journal article

2006

CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis

Shim, J. H., Xiao, C. C., Hayden, M. S., Lee, K. Y., Trombetta, E. S., Pypaert, M., . . . Ghosh, S. (2006). CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. JOURNAL OF CELL BIOLOGY, 172(7), 1045-1056. doi:10.1083/jcb.200509041

DOI
10.1083/jcb.200509041
Journal article

2005

The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature

Wilm, B., Ipenberg, A., Hastie, N. D., Burch, J. B. E., & Bader, D. M. (2005). The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature. DEVELOPMENT, 132(23), 5317-5328. doi:10.1242/dev.02141

DOI
10.1242/dev.02141
Journal article

2004

The forkhead genes, <i>Foxc1</i> and <i>Foxc2</i>, regulate paraxial versus intermediate mesoderm cell fate

Wilm, B., James, R. G., Schultheiss, T. A., & Hogan, B. L. M. (2004). The forkhead genes, <i>Foxc1</i> and <i>Foxc2</i>, regulate paraxial versus intermediate mesoderm cell fate. DEVELOPMENTAL BIOLOGY, 271(1), 176-189. doi:10.1016/j.ydbio.2004.03.034

DOI
10.1016/j.ydbio.2004.03.034
Journal article

2003

<i>Undulated shod-tail</i> deletion mutation in the mouse ablates <i>Pax1</i> and leads to ectopic activation of neighboring <i>Nkx2-2</i> in domains that normally express <i>Pax1</i>

Kokubu, C., Wilm, B., Kokubu, T., Wahl, M., Rodrigo, I., Sakai, N., . . . Imai, K. (2003). <i>Undulated shod-tail</i> deletion mutation in the mouse ablates <i>Pax1</i> and leads to ectopic activation of neighboring <i>Nkx2-2</i> in domains that normally express <i>Pax1</i>. GENETICS, 165(1), 299-307. Retrieved from https://www.webofscience.com/

Journal article

1999

Pax1 and Pax9 synergistically regulate vertebral column development

Peters, H., Wilm, B., Sakai, N., Imai, K., Maas, R., & Balling, R. (1999). Pax1 and Pax9 synergistically regulate vertebral column development. DEVELOPMENT, 126(23), 5399-5408. Retrieved from https://www.webofscience.com/

Journal article

Identification of caspases and apoptosis in the simple metazoan <i>Hydra</i>

Cikala, M., Wilm, B., Hobmayer, E., Böttger, A., & David, C. N. (1999). Identification of caspases and apoptosis in the simple metazoan <i>Hydra</i>. CURRENT BIOLOGY, 9(17), 959-962. doi:10.1016/S0960-9822(99)80423-0

DOI
10.1016/S0960-9822(99)80423-0
Journal article

1998

Targeted disruption of <i>Pax1</i> defines its null phenotype and proves haploinsufficiency

Wilm, B., Dahl, E., Peters, H., Balling, R., & Imai, K. (1998). Targeted disruption of <i>Pax1</i> defines its null phenotype and proves haploinsufficiency. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 95(15), 8692-8697. doi:10.1073/pnas.95.15.8692

DOI
10.1073/pnas.95.15.8692
Journal article