Publications
Selected publications
- Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism (Journal article - 2018)
- Ecological and microbiological diversity of chigger mites, including vectors of scrub typhus, on small mammals across stratified habitats in Thailand (Journal article - 2019)
- Emodepside targets SLO-1 channels of <i>Onchocerca ochengi</i> and induces broad anthelmintic effects in a bovine model of onchocerciasis (Journal article - 2021)
- Diminutive, degraded but dissimilar: <i>Wolbachia</i> genomes from filarial nematodes do not conform to a single paradigm. (Journal article - 2020)
- Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of <i>Wolbachia</i> in Tick Cell Lines. (Journal article - 2020)
2024
Intra- and interspecific variation of Amblyomma ticks from southern Africa
Smit, A., Mulandane, F., Labuschagne, M., Wójick, S. H., Malabwa, C., Sili, G., . . . Neves, L. (n.d.). Intra- and interspecific variation of Amblyomma ticks from southern Africa. Parasites and Vectors, 17(1). doi:10.1186/s13071-024-06394-3
Cappable-Seq reveals the transcriptional landscape of stress responses in the bacterial endosymbiont<i>Wolbachia</i>
Infection Rates and Characterisation of Rickettsia africae (Rickettsiaceae) Detected in Amblyomma Species from Southern Africa
Smit, A., Mulandane, F. C., Wójcik, S. H., Malabwa, C., Sili, G., Mandara, S., . . . Neves, L. (n.d.). Infection Rates and Characterisation of Rickettsia africae (Rickettsiaceae) Detected in Amblyomma Species from Southern Africa. Microorganisms, 12(8), 1663. doi:10.3390/microorganisms12081663
Establishment and partial characterisation of a new cell line derived from adult tissues of the tsetse fly Glossina morsitans morsitans.
Bell-Sakyi, L., Haines, L. R., Petrucci, G., Beliavskaia, A., Hartley, C., Khoo, J. J., . . . Darby, A. C. (2024). Establishment and partial characterisation of a new cell line derived from adult tissues of the tsetse fly Glossina morsitans morsitans.. Parasites & vectors, 17(1), 231. doi:10.1186/s13071-024-06310-9
Microbiome and mitogenomics of the chigger mite Pentidionis agamae: potential role as an Orientia vector and associations with divergent clades of Wolbachia and Borrelia
Alkathiry, H. A., Alghamdi, S. Q., Sinha, A., Margos, G., Stekolnikov, A. A., Alagaili, A. N., . . . Khoo, J. J. (2024). Microbiome and mitogenomics of the chigger mite Pentidionis agamae: potential role as an Orientia vector and associations with divergent clades of Wolbachia and Borrelia. BMC Genomics, 25(1). doi:10.1186/s12864-024-10301-6
Multi-Locus Sequence Analysis Indicates Potential Cryptic Speciation in the Chigger Mite <i>Neoschoengastia gallinarum</i> (Hatori, 1920) Parasitising Birds in Asia.
Rajasegaran, P., Koosakulnirand, S., Tan, K. -K., Khoo, J. J., Suliman, Y., Mansor, M. S., . . . Makepeace, B. L. (2024). Multi-Locus Sequence Analysis Indicates Potential Cryptic Speciation in the Chigger Mite <i>Neoschoengastia gallinarum</i> (Hatori, 1920) Parasitising Birds in Asia.. Animals : an open access journal from MDPI, 14(6), 980. doi:10.3390/ani14060980
2023
On the taxonomy of chigger mites (Acariformes: Trombiculidae) parasitizing birds in Thailand and Malaysia, with the description of a new species
Koosakulnirand, S., Rajasegaran, P., Alkathiry, H. A., Chaisiri, K., Round, P. D., Eiamampai, K., . . . Makepeace, B. L. (2023). On the taxonomy of chigger mites (Acariformes: Trombiculidae) parasitizing birds in Thailand and Malaysia, with the description of a new species. Acarologia, 63(4), 1109-1138. doi:10.24349/yt89-g1ei
Predicting the distribution of Ixodes ricinus and Dermacentor reticulatus in Europe: a comparison of climate niche modelling approaches.
Noll, M., Wall, R., Makepeace, B. L., Newbury, H., Adaszek, L., Bødker, R., . . . Rose Vineer, H. (2023). Predicting the distribution of Ixodes ricinus and Dermacentor reticulatus in Europe: a comparison of climate niche modelling approaches.. Parasites & vectors, 16(1), 384. doi:10.1186/s13071-023-05959-y
Sympatry of Amblyomma eburneum and Amblyomma variegatum on African buffaloes and prevalence of pathogens in ticks.
Smit, A., Mulandane, F. C., Wojcik, S. H., Horak, I. G., Makepeace, B. L., Morar-Leather, D., & Neves, L. (2023). Sympatry of Amblyomma eburneum and Amblyomma variegatum on African buffaloes and prevalence of pathogens in ticks.. Ticks and tick-borne diseases, 14(6), 102247. doi:10.1016/j.ttbdis.2023.102247
The chigger microbiome: big questions in a tiny world
Chaisiri, K., Linsuwanon, P., & Makepeace, B. L. (2023). The chigger microbiome: big questions in a tiny world. TRENDS IN PARASITOLOGY, 39(8), 696-707. doi:10.1016/j.pt.2023.05.002
Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates
Makepeace, B. (2023). Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates. Vaccines, 11(7). doi:10.3390/vaccines11071212
Metagenomics of culture isolates and insect tissue illuminate the evolution of <i>Wolbachia</i>, <i>Rickettsia</i> and <i>Bartonella</i> symbionts in <i>Ctenocephalides</i> spp. fleas.
Beliavskaia, A., Tan, K. -K., Sinha, A., Husin, N. A., Lim, F. S., Loong, S. K., . . . Khoo, J. J. (2023). Metagenomics of culture isolates and insect tissue illuminate the evolution of <i>Wolbachia</i>, <i>Rickettsia</i> and <i>Bartonella</i> symbionts in <i>Ctenocephalides</i> spp. fleas.. Microbial genomics, 9(7). doi:10.1099/mgen.0.001045
The evolution of intramitochondriality in Midichloria bacteria.
Floriano, A. M., Batisti Biffignandi, G., Castelli, M., Olivieri, E., Clementi, E., Comandatore, F., . . . Sassera, D. (2023). The evolution of intramitochondriality in Midichloria bacteria.. Environmental microbiology. doi:10.1111/1462-2920.16446
<i>Wolbachia</i> springs eternal: symbiosis in Collembola is associated with host ecology
Rodrigues, J., Lefoulon, E., Gavotte, L., Perillat-Sanguinet, M., Makepeace, B., Martin, C., & D'Haese, C. A. (2023). <i>Wolbachia</i> springs eternal: symbiosis in Collembola is associated with host ecology. Royal Society Open Science, 10(5). doi:10.1098/rsos.230288
Distribution of ticks in the Western Palearctic: an updated systematic review (2015-2021).
Noll, M., Wall, R., Makepeace, B. L., & Vineer, H. R. (2023). Distribution of ticks in the Western Palearctic: an updated systematic review (2015-2021).. Parasites & vectors, 16(1), 141. doi:10.1186/s13071-023-05773-6
Molecular Detection of<i> Candidatus</i> Orientia chuto in Wildlife, Saudi Arabia
Alkathiry, H. A., Alghamdi, S. Q., Morgan, H. E. J., Noll, M. E., Khoo, J. J., Alagaili, A. N., & Makepeace, B. L. (2023). Molecular Detection of<i> Candidatus</i> Orientia chuto in Wildlife, Saudi Arabia. EMERGING INFECTIOUS DISEASES, 29(2), 402-406. doi:10.3201/eid2902.221131
Molecular Surveillance for Vector-Borne Bacteria in Rodents and Tree Shrews of Peninsular Malaysia Oil Palm Plantations
Mohd-Azami, S. N. I., Loong, S. K., Khoo, J. J., Husin, N. A., Lim, F. S., Mahfodz, N. H., . . . AbuBakar, S. (n.d.). Molecular Surveillance for Vector-Borne Bacteria in Rodents and Tree Shrews of Peninsular Malaysia Oil Palm Plantations. Tropical Medicine and Infectious Disease, 8(2), 74. doi:10.3390/tropicalmed8020074
Additions to the chigger mite fauna (Acariformes: Trombiculidae) of Saudi Arabia, with the description of a new species
Alghamdi, S. Q., Alkathiry, H. A., Stekolnikov, A. A., Alagaili, A. N., & Makepeace, B. L. (2023). Additions to the chigger mite fauna (Acariformes: Trombiculidae) of Saudi Arabia, with the description of a new species. ACAROLOGIA. doi:10.24349/dsrx-oryy
2022
Habitat and Season Drive Chigger Mite Diversity and Abundance on Small Mammals in Peninsular Malaysia
Alkathiry, H., Al-Rofaai, A., Ya'cob, Z., Cutmore, T. S., Mohd-Azami, S. N. I., Husin, N. A., . . . Khoo, J. J. (2022). Habitat and Season Drive Chigger Mite Diversity and Abundance on Small Mammals in Peninsular Malaysia. PATHOGENS, 11(10). doi:10.3390/pathogens11101087
Symbionts on the Brain: How <i>Wolbachia</i> Is Strictly Corralled in Some Neotropical <i>Drosophila</i> spp.
Voronin, D., & Makepeace, B. L. (2022). Symbionts on the Brain: How <i>Wolbachia</i> Is Strictly Corralled in Some Neotropical <i>Drosophila</i> spp.. MBIO, 13(4). doi:10.1128/mbio.01182-22
Co-Administration of Adjuvanted Recombinant <i>Ov</i>-103 and <i>Ov</i>-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine <i>Onchocerca ochengi</i> Infection Model of Human Onchocerciasis
Luu, L., Bah, G. S., Okah-Nnane, N. H., Hartley, C. S., Glover, A. F., Walsh, T. R., . . . Graham-Brown, J. (2022). Co-Administration of Adjuvanted Recombinant <i>Ov</i>-103 and <i>Ov</i>-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine <i>Onchocerca ochengi</i> Infection Model of Human Onchocerciasis. VACCINES, 10(6). doi:10.3390/vaccines10060861
New Cell Lines Derived from European Tick Species
Bell-Sakyi, L., Hartley, C. S., Khoo, J. J., Forth, J. H., Palomar, A. M., & Makepeace, B. L. (2022). New Cell Lines Derived from European Tick Species. MICROORGANISMS, 10(6). doi:10.3390/microorganisms10061086
Molecular evidence of rat bocavirus among rodents in Peninsular Malaysia.
Mohd-Azami, S. N. I., Loong, S. K., Khoo, J. J., Sahimin, N., Lim, F. S., Husin, N. A., . . . Abubakar, S. (2022). Molecular evidence of rat bocavirus among rodents in Peninsular Malaysia.. The Journal of veterinary medical science. doi:10.1292/jvms.22-0037
Onchocerca lupi in imported dogs in the UK: implications for animal and public health
McGarry, J. W., Carrozza, R., Bradley, C., Latrofa, M. S., Makepeace, B. L., & Otranto, D. (n.d.). Onchocerca lupi in imported dogs in the UK: implications for animal and public health. BMC Veterinary Research, 18(1). doi:10.1186/s12917-022-03169-9
2021
A dual endosymbiosis supports nutritional adaptation to hematophagy in the invasive tick <i>Hyalomma marginatum</i>
Buysse, M., Floriano, A. M., Gottlieb, Y., Nardi, T., Comandatore, F., Olivieri, E., . . . Duron, O. (2021). A dual endosymbiosis supports nutritional adaptation to hematophagy in the invasive tick <i>Hyalomma marginatum</i>. ELIFE, 10. doi:10.7554/eLife.72747
Development of a recombinant vaccine against human onchocerciasis
Abraham, D., Graham-Brown, J., Carter, D., Gray, S. A., Hess, J. A., Makepeace, B. L., & Lustigman, S. (2021). Development of a recombinant vaccine against human onchocerciasis. EXPERT REVIEW OF VACCINES, 20(11), 1459-1470. doi:10.1080/14760584.2021.1977125
Automatic barcode gap discovery reveals diverse clades of <i>Rhipicephalus</i> spp. and <i>Haemaphysalis</i> spp. ticks from small mammals in 'Asir, Saudi Arabia
Alghamdi, S. Q., Low, V. L., Alkathiry, H. A., Alagaili, A. N., McGarry, J. W., & Makepeace, B. L. (2021). Automatic barcode gap discovery reveals diverse clades of <i>Rhipicephalus</i> spp. and <i>Haemaphysalis</i> spp. ticks from small mammals in 'Asir, Saudi Arabia. PARASITES & VECTORS, 14(1). doi:10.1186/s13071-021-05049-x
Isolation in Natural Host Cell Lines of Wolbachia Strains wPip from the Mosquito Culex pipiens and wPap from the Sand Fly Phlebotomus papatasi
Bell-Sakyi, L., Beliavskaia, A., Hartley, C. S., Jones, L., Luu, L., Haines, L. R., . . . Makepeace, B. L. (2021). Isolation in Natural Host Cell Lines of Wolbachia Strains wPip from the Mosquito Culex pipiens and wPap from the Sand Fly Phlebotomus papatasi. INSECTS, 12(10). doi:10.3390/insects12100871
Editorial: Genetics Architecture and Underlying Molecular Mechanisms in Host-Pathogen Interactions
Makepeace, B. L., Psifidi, A., Robledo, D., & Xia, D. (2021). Editorial: Genetics Architecture and Underlying Molecular Mechanisms in Host-Pathogen Interactions. FRONTIERS IN GENETICS, 12. doi:10.3389/fgene.2021.695109
Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration
Kruecken, J., Holden-Dye, L., Keiser, J., Prichard, R. K., Townson, S., Makepeace, B. L., . . . Kulke, D. (2021). Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration. PLOS PATHOGENS, 17(7). doi:10.1371/journal.ppat.1009682
Emodepside targets SLO-1 channels of <i>Onchocerca ochengi</i> and induces broad anthelmintic effects in a bovine model of onchocerciasis
Bah, G. S., Schneckener, S., Hahnel, S. R., Bayang, N. H., Fieseler, H., Schmuck, G. M., . . . Makepeace, B. L. (2021). Emodepside targets SLO-1 channels of <i>Onchocerca ochengi</i> and induces broad anthelmintic effects in a bovine model of onchocerciasis. PLOS PATHOGENS, 17(6). doi:10.1371/journal.ppat.1009601
Automatic barcode gap discovery reveals diverse clades of Rhipicephalus spp. and Haemaphysalis spp. ticks from small mammals in 'Asir, Saudi Arabia
Bacterial Pathogens and Symbionts Harboured by Ixodes ricinus Ticks Parasitising Red Squirrels in the United Kingdom
Luu, L., Palomar, A. M., Farrington, G., Schilling, A. -K., Premchand-Branker, S., McGarry, J., . . . Bell-Sakyi, L. (n.d.). Bacterial Pathogens and Symbionts Harboured by Ixodes ricinus Ticks Parasitising Red Squirrels in the United Kingdom. Pathogens, 10(4), 458. doi:10.3390/pathogens10040458
<i>Onchocerca volvulus</i> bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice
Ryan, N. M., Hess, J. A., de Villena, F. P. -M., Leiby, B. E., Shimada, A., Yu, L., . . . Abraham, D. (2021). <i>Onchocerca volvulus</i> bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice. NPJ VACCINES, 6(1). doi:10.1038/s41541-020-00276-2
2020
Diminutive, degraded but dissimilar: <i>Wolbachia</i> genomes from filarial nematodes do not conform to a single paradigm.
Lefoulon, E., Clark, T., Guerrero, R., Cañizales, I., Cardenas-Callirgos, J. M., Junker, K., . . . Slatko, B. E. (2020). Diminutive, degraded but dissimilar: <i>Wolbachia</i> genomes from filarial nematodes do not conform to a single paradigm.. Microbial genomics, 6(12). doi:10.1099/mgen.0.000487
Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of <i>Wolbachia</i> in Tick Cell Lines.
Khoo, J. J., Kurtti, T. J., Husin, N. A., Beliavskaia, A., Lim, F. S., Zulkifli, M. M. S., . . . Bell-Sakyi, L. (2020). Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of <i>Wolbachia</i> in Tick Cell Lines.. Microorganisms, 8(7), E988. doi:10.3390/microorganisms8070988
Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of Wolbachia in Tick Cell Lines
Khoo, J. J., Kurtti, T., Husin, N. A., Beliavskaia, A., Lim, F. S., Zulkifli, M. M. S., . . . Bell-Sakyi, L. (2020). Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of Wolbachia in Tick Cell Lines. Microorganisms, 8(7). doi:10.3390/microorganisms8070988
Marginalized mites: Neglected vectors of neglected diseases.
Weitzel, T., Makepeace, B. L., Elliott, I., Chaisiri, K., Richards, A. L., & Newton, P. N. (2020). Marginalized mites: Neglected vectors of neglected diseases. PLOS NEGLECTED TROPICAL DISEASES, 14(7). doi:10.1371/journal.pntd.0008297
<i>Rickettsia buchneri</i>, symbiont of the deer tick <i>Ixodes scapularis</i>, can colonise the salivary glands of its host
Al-Khafaji, A. M., Armstrong, S. D., Boccazzi, I. V., Gaiarsa, S., Sinha, A., Li, Z., . . . Makepeace, B. L. (2020). <i>Rickettsia buchneri</i>, symbiont of the deer tick <i>Ixodes scapularis</i>, can colonise the salivary glands of its host. TICKS AND TICK-BORNE DISEASES, 11(1). doi:10.1016/j.ttbdis.2019.101299
2019
Ecological and microbiological diversity of chigger mites, including vectors of scrub typhus, on small mammals across stratified habitats in Thailand
Chaisiri, K., Gill, A. C., Stekolnikov, A. A., Hinjoy, S., McGarry, J. W., Darby, A. C., . . . Makepeace, B. (2019). Ecological and microbiological diversity of chigger mites, including vectors of scrub typhus, on small mammals across stratified habitats in Thailand. Animal Microbiome, 1. doi:10.1186/s42523-019-0019-x
First data on chigger mites (Acariformes: Trombiculidae) of Saudi Arabia, with a description of four new species
Stekolnikov, A. A., Al-Ghamdi, S. Q., Alagaili, A. N., & Makepeace, B. L. (n.d.). First data on chigger mites (Acariformes: Trombiculidae) of Saudi Arabia, with a description of four new species. Systematic and Applied Acarology, 24(10), 1937-1963. doi:10.11158/saa.24.10.12
Characterisation of a novel glycosylated glutathione transferase of Onchocerca ochengi, closest relative of the human river blindness parasite.
Rose, C., Praulins, G., Armstrong, S. D., Casas-Sanchez, A., Davis, J., Molyneux, G., . . . Acosta-Serrano, A. (2019). Characterisation of a novel glycosylated glutathione transferase of Onchocerca ochengi, closest relative of the human river blindness parasite.. Parasitology, 1-27. doi:10.1017/s0031182019000763
Aquatic Hemiptera in Southwest Cameroon: Biodiversity of Potential Reservoirs of <i>Mycobacterium ulcerans</i> and Multiple <i>Wolbachia</i> Sequence Types Revealed by Metagenomics
Esemu, S. N., Dong, X., Kfusi, A. J., Hartley, C. S., Ndip, R. N., Ndip, L. M., . . . Makepeace, B. L. (2019). Aquatic Hemiptera in Southwest Cameroon: Biodiversity of Potential Reservoirs of <i>Mycobacterium ulcerans</i> and Multiple <i>Wolbachia</i> Sequence Types Revealed by Metagenomics. DIVERSITY-BASEL, 11(12). doi:10.3390/d11120225
Comparative genomics of the major parasitic worms
Coghlan, A., Tyagi, R., Cotton, J. A., Holroyd, N., Rosa, B. A., Tsai, I. J., . . . Blaxter, M. L. (2019). Comparative genomics of the major parasitic worms. Nature Genetics, 51, 163-174. doi:10.1038/s41588-018-0262-1
Meeting the challenge of tick-borne disease control: A proposal for 1000 <i>Ixodes</i> genomes
Murgia, M. V., Bell-Sakyi, L., de la Fuente, J., Kurtti, T. J., Makepeace, B. L., Mans, B., . . . Hill, C. A. (2019). Meeting the challenge of tick-borne disease control: A proposal for 1000 <i>Ixodes</i> genomes. TICKS AND TICK-BORNE DISEASES, 10(1), 213-218. doi:10.1016/j.ttbdis.2018.08.009
Multi-locus sequence typing of <i>Ixodes ricinus</i> and its symbiont <i>Candidatus</i> Midichloria mitochondrii across Europe reveals evidence of local co-cladogenesis in Scotland
Al-Khafaji, A. M., Clegg, S. R., Pinder, A. C., Luu, L., Hansford, K. M., Seelig, F., . . . Makepeace, B. L. (2019). Multi-locus sequence typing of <i>Ixodes ricinus</i> and its symbiont <i>Candidatus</i> Midichloria mitochondrii across Europe reveals evidence of local co-cladogenesis in Scotland. TICKS AND TICK-BORNE DISEASES, 10(1), 52-62. doi:10.1016/j.ttbdis.2018.08.016
2018
Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism
Dong, X., Chaisiri, K., Xia, D., Armstrong, S. D., Fang, Y., Donnelly, M. J., . . . Makepeace, B. L. (2018). Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism. GigaScience, 7(12), 33 pages. doi:10.1093/gigascience/giy127
The Tick Cell Biobank: A global resource for <i>in vitro</i> research on ticks, other arthropods and the pathogens they transmit
Bell-Sakyi, L., Darby, A., Baylis, M., & Makepeace, B. L. (2018). The Tick Cell Biobank: A global resource for <i>in vitro</i> research on ticks, other arthropods and the pathogens they transmit. TICKS AND TICK-BORNE DISEASES, 9(5), 1364-1371. doi:10.1016/j.ttbdis.2018.05.015
Autofluorescence microscopy for paired-matched morphological and molecular identification of individual chigger mites (Acari: Trombiculidae), the vectors of scrub typhus
Kumlert, R., Chaisiri, K., Anantatat, T., Stekolnikov, A. A., Morand, S., Prasartvit, A., . . . Paris, D. H. (2018). Autofluorescence microscopy for paired-matched morphological and molecular identification of individual chigger mites (Acari: Trombiculidae), the vectors of scrub typhus. PLOS ONE, 13(3). doi:10.1371/journal.pone.0193163
Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism
Dong, X., Chaisiri, K., Xia, D., Armstrong, S., Fang, Y., Donnelly, M., . . . Makepeace, B. (2018). Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism. doi:10.1101/259044
Onchocerca volvulus: The Road from Basic Biology to a Vaccine
Lustigman, S., Makepeace, B. L., Klei, T. R., Babayan, S. A., Hotez, P., Abraham, D., & Bottazzi, M. E. (2018). <i>Onchocerca volvulus</i>: The Road from Basic Biology to a Vaccine. TRENDS IN PARASITOLOGY, 34(1), 64-79. doi:10.1016/j.pt.2017.08.011
2017
Lipid profiling of the filarial nematodes <i>Onchocerca volvulus</i>, <i>Onchocerca ochengi</i> and <i>Litomosoides sigmodontis</i> reveals the accumulation of nematode-specific ether phospholipids in the host
Wewer, V., Makepeace, B. L., Tanya, V. N., Peisker, H., Pfarr, K., Hoerauf, A., & Doermann, P. (2017). Lipid profiling of the filarial nematodes <i>Onchocerca volvulus</i>, <i>Onchocerca ochengi</i> and <i>Litomosoides sigmodontis</i> reveals the accumulation of nematode-specific ether phospholipids in the host. INTERNATIONAL JOURNAL FOR PARASITOLOGY, 47(14), 903-912. doi:10.1016/j.ijpara.2017.06.001
Whence river blindness? The domestication of mammals and host-parasite co-evolution in the nematode genus <i>Onchocerca</i>
Lefoulon, E., Giannelli, A., Makepeace, B. L., Mutafchiev, Y., Townson, S., Uni, S., . . . Martin, C. (2017). Whence river blindness? The domestication of mammals and host-parasite co-evolution in the nematode genus <i>Onchocerca</i>. INTERNATIONAL JOURNAL FOR PARASITOLOGY, 47(8), 457-470. doi:10.1016/j.ijpara.2016.12.009
Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae, is shaped by the parasitic life history
Dong, X., Armstrong, S., Xia, D., Makepeace, B., Darby, A. C., & Kadowaki, T. (2017). Draft genome of the honey bee ectoparasitic mite, Tropilaelaps mercedesae, is shaped by the parasitic life history. GigaScience, 6(3). doi:10.1093/gigascience/gix008
The potential role of Wolbachia in controlling the transmission of emerging human arboviral infections.
Kamtchum-Tatuene, J., Makepeace, B. L., Benjamin, L., Baylis, M., & Solomon, T. (2017). The potential role of <i>Wolbachia</i> in controlling the transmission of emerging human arboviral infections. CURRENT OPINION IN INFECTIOUS DISEASES, 30(1), 108-116. doi:10.1097/QCO.0000000000000342
2016
25 Years of the Onchocerca ochengi Model.
Makepeace, B. L., & Tanya, V. N. (2016). 25 Years of the <i>Onchocerca</i> <i>ochengi</i> Model. TRENDS IN PARASITOLOGY, 32(12), 966-978. doi:10.1016/j.pt.2016.08.013
Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle
Armstrong, S. D., Xia, D., Bah, G. S., Krishna, R., Ngangyung, H. F., LaCourse, E. J., . . . Makepeace, B. L. (2016). Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle. Molecular and Cellular Proteomics, 15(8), 2554-2575. doi:10.1074/mcp.M115.055640
A Revised Checklist of Chigger Mites (Acari: Trombiculidae) From Thailand, with the Description of Three New Species
Chaisiri, K., Stekolnikov, A. A., Makepeace, B. L., & Morand, S. (2016). A Revised Checklist of Chigger Mites (Acari: Trombiculidae) From Thailand, with the Description of Three New Species. JOURNAL OF MEDICAL ENTOMOLOGY, 53(2), 321-342. doi:10.1093/jme/tjv244
Breakdown of coevolution between symbiotic bacteria <i>Wolbachia</i> and their filarial hosts
Lefoulon, E., Bain, O., Makepeace, B. L., d'Haese, C., Uni, S., Martin, C., & Gavotte, L. (2016). Breakdown of coevolution between symbiotic bacteria <i>Wolbachia</i> and their filarial hosts. PEERJ, 4. doi:10.7717/peerj.1840
Wolbachia
Makepeace, B. L., & Gill, A. C. (2016). Wolbachia. In Rickettsiales (pp. 465-512). Springer International Publishing. doi:10.1007/978-3-319-46859-4_21
2015
Supergroup <i>C Wolbachia</i>, mutualist symbionts of filarial nematodes, have a distinct genome structure
Comandatore, F., Cordaux, R., Bandi, C., Blaxter, M., Darby, A., Makepeace, B. L., . . . Sassera, D. (2015). Supergroup <i>C Wolbachia</i>, mutualist symbionts of filarial nematodes, have a distinct genome structure. OPEN BIOLOGY, 5(12). doi:10.1098/rsob.150099
The case for vaccine development in the strategy to eradicate river blindness (onchocerciasis) from Africa
Makepeace, B. L., Babayan, S. A., Lustigman, S., & Taylor, D. W. (2015). The case for vaccine development in the strategy to eradicate river blindness (onchocerciasis) from Africa. EXPERT REVIEW OF VACCINES, 14(9), 1163-1165. doi:10.1586/14760584.2015.1059281
Immunotherapy with mutated onchocystatin fails to enhance the efficacy of a sub-lethal oxytetracycline regimen against <i>Onchocerca ochengi</i>
Bah, G. S., Tanya, V. N., & Makepeace, B. L. (2015). Immunotherapy with mutated onchocystatin fails to enhance the efficacy of a sub-lethal oxytetracycline regimen against <i>Onchocerca ochengi</i>. VETERINARY PARASITOLOGY, 212(1-2), 25-34. doi:10.1016/j.vetpar.2015.06.005
Symbiosis in an overlooked microcosm: a systematic review of the bacterial flora of mites
Chaisiri, K., McGarry, J. W., Morand, S., & Makepeace, B. L. (2015). Symbiosis in an overlooked microcosm: a systematic review of the bacterial flora of mites. PARASITOLOGY, 142(9), 1152-1162. doi:10.1017/S0031182015000530
Extracellular <i>Onchocerca</i>-derived small RNAs in host nodules and blood
Quintana, J. F., Makepeace, B. L., Babayan, S. A., Ivens, A., Pfarr, K. M., Blaxter, M., . . . Buck, A. H. (2015). Extracellular <i>Onchocerca</i>-derived small RNAs in host nodules and blood. PARASITES & VECTORS, 8. doi:10.1186/s13071-015-0656-1
HOW FILARIAL NEMATODE GENOMES HAVE ACCELERATED THE DISCOVERY OF VACCINE AND DIAGNOSTIC BIOMARKER CANDIDATES.
Makepeace, B. L., Buck, A. H., Carlow, C. K. S., Babayan, S. A., Tanya, V. N., Taylor, D. W., & Blaxter, M. L. (2015). HOW FILARIAL NEMATODE GENOMES HAVE ACCELERATED THE DISCOVERY OF VACCINE AND DIAGNOSTIC BIOMARKER CANDIDATES.. JOURNAL OF NEMATOLOGY, 47(3), 253. Retrieved from https://www.webofscience.com/
The Onchocerciasis Vaccine for Africa-TOVA-Initiative
Hotez, P. J., Bottazzi, M. E., Zhan, B., Makepeace, B. L., Klei, T. R., Abraham, D., . . . Lustigman, S. (2015). The Onchocerciasis Vaccine for Africa-TOVA-Initiative. PLOS NEGLECTED TROPICAL DISEASES, 9(1). doi:10.1371/journal.pntd.0003422
2014
A Simple Isothermal DNA Amplification Method to Screen Black Flies for <i>Onchocerca volvulus</i> Infection
Alhassan, A., Makepeace, B. L., LaCourse, E. J., Osei-Atweneboana, M. Y., & Carlow, C. K. S. (2014). A Simple Isothermal DNA Amplification Method to Screen Black Flies for <i>Onchocerca volvulus</i> Infection. PLOS ONE, 9(10). doi:10.1371/journal.pone.0108927
Comparative Analysis of the Secretome from a Model Filarial Nematode (<i>Litomosoides sigmodontis</i>) Reveals Maximal Diversity in Gravid Female Parasites
Armstrong, S. D., Babayan, S. A., Lhermitte-Vallarino, N., Gray, N., Xia, D., Martin, C., . . . Makepeace, B. L. (2014). Comparative Analysis of the Secretome from a Model Filarial Nematode (<i>Litomosoides sigmodontis</i>) Reveals Maximal Diversity in Gravid Female Parasites. MOLECULAR & CELLULAR PROTEOMICS, 13(10), 2527-2544. doi:10.1074/mcp.M114.038539
Palaeosymbiosis Revealed by Genomic Fossils of Wolbachia in a Strongyloidean Nematode
Koutsovoulos, G., Makepeace, B., Ngwang, T., & Blaxter, M. (2014). Palaeosymbiosis Revealed by Genomic Fossils of Wolbachia in a Strongyloidean Nematode. PLoS Genetics, 10(6). doi:10.1371/journal.pgen.1004397
Integrated transcriptomic and proteomic analysis of the global response of <i>Wolbachia</i> to doxycycline-induced stress
Darby, A. C., Gill, A. C., Armstrong, S. D., Hartley, C. S., Xia, D., Wastling, J. M., & Makepeace, B. L. (2014). Integrated transcriptomic and proteomic analysis of the global response of <i>Wolbachia</i> to doxycycline-induced stress. ISME JOURNAL, 8(4), 925-937. doi:10.1038/ismej.2013.192
Efficacy of Three-Week Oxytetracycline or Rifampin Monotherapy Compared with a Combination Regimen against the Filarial Nematode <i>Onchocerca ochengi</i>
Bah, G. S., Ward, E. L., Srivastava, A., Trees, A. J., Tanya, V. N., & Makepeace, B. L. (2014). Efficacy of Three-Week Oxytetracycline or Rifampin Monotherapy Compared with a Combination Regimen against the Filarial Nematode <i>Onchocerca ochengi</i>. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 58(2), 801-810. doi:10.1128/AAC.01995-13
Iron Necessity: The Secret of <i>Wolbachia</i>'s Success?
Gill, A. C., Darby, A. C., & Makepeace, B. L. (2014). Iron Necessity: The Secret of <i>Wolbachia</i>'s Success?. PLOS NEGLECTED TROPICAL DISEASES, 8(10). doi:10.1371/journal.pntd.0003224
Vaccines, Polypeptides, and Nucleic Acids
Makepeace, B. (2014). Vaccines, Polypeptides, and Nucleic Acids.
2013
Phylogenomics and Analysis of Shared Genes Suggest a Single Transition to Mutualism in <i>Wolbachia</i> of Nematodes
Comandatore, F., Sassera, D., Montagna, M., Kumar, S., Koutsovoulos, G., Thomas, G., . . . Blaxter, M. (2013). Phylogenomics and Analysis of Shared Genes Suggest a Single Transition to Mutualism in <i>Wolbachia</i> of Nematodes. GENOME BIOLOGY AND EVOLUTION, 5(9), 1668-1674. doi:10.1093/gbe/evt125
Phylogenomics and Analysis of Shared Genes Suggest a Single Transition to Mutualism in Wolbachia of Nematodes
Comandatore, F., Sassera, D., Montagna, M., Kumar, S., Koutsovoulos, G., Thomas, G., . . . Blaxter, M. (2013). Phylogenomics and Analysis of Shared Genes Suggest a Single Transition to Mutualism in Wolbachia of Nematodes. Genome Biology and Evolution, 5(9), 1668-1674. doi:10.1093/gbe/evt125
2012
Analysis of gene expression from the <i>Wolbachia</i> genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis
Darby, A. C., Armstrong, S. D., Bah, G. S., Kaur, G., Hughes, M. A., Kay, S. M., . . . Makepeace, B. L. (2012). Analysis of gene expression from the <i>Wolbachia</i> genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis. GENOME RESEARCH, 22(12), 2467-2477. doi:10.1101/gr.138420.112
Granulocytes in helminth infection -- who is calling the shots?
Makepeace, B. L., Martin, C., Turner, J. D., & Specht, S. (2012). Granulocytes in helminth infection -- who is calling the shots?. Current medicinal chemistry, 19(10), 1567-1586. doi:10.2174/092986712799828337
2011
A worm's best friend: recruitment of neutrophils by Wolbachia confounds eosinophil degranulation against the filarial nematode Onchocerca ochengi.
Hansen, R. D. E., Trees, A. J., Bah, G. S., Hetzel, U., Martin, C., Bain, O., . . . Makepeace, B. L. (2011). A worm's best friend: recruitment of neutrophils by Wolbachia confounds eosinophil degranulation against the filarial nematode Onchocerca ochengi.. Proceedings. Biological sciences, 278(1716), 2293-2302. doi:10.1098/rspb.2010.2367
2010
Onchocerca armillata contains the endosymbiotic bacterium Wolbachia and elicits a limited inflammatory response.
Neary, J. M., Trees, A. J., Ekale, D. D., Tanya, V. N., Hetzel, U., & Makepeace, B. L. (2010). Onchocerca armillata contains the endosymbiotic bacterium Wolbachia and elicits a limited inflammatory response.. Veterinary parasitology, 174(3-4), 267-276. doi:10.1016/j.vetpar.2010.08.031
2009
Immunisation with a Multivalent, Subunit Vaccine Reduces Patent Infection in a Natural Bovine Model of Onchocerciasis during Intense Field Exposure
Makepeace, B. L., Jensen, S. A., Laney, S. J., Nfon, C. K., Njongmeta, L. M., Tanya, V. N., . . . Trees, A. J. (n.d.). Immunisation with a Multivalent, Subunit Vaccine Reduces Patent Infection in a Natural Bovine Model of Onchocerciasis during Intense Field Exposure. PLoS Neglected Tropical Diseases, 3(11), e544. doi:10.1371/journal.pntd.0000544
2008
UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.
Dec Bronsvoort, B. M., Makepeace, B. L., Renz, A., Tanya, V. N., Fleckenstein, L., Ekale, D., & Trees, A. J. (2008). UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.. Parasites & vectors, 1(1), 18. doi:10.1186/1756-3305-1-18
Of mice, cattle, and humans: the immunology and treatment of river blindness.
Allen, J. E., Adjei, O., Bain, O., Hoerauf, A., Hoffmann, W. H., Makepeace, B. L., . . . Taylor, D. W. (2008). Of mice, cattle, and humans: the immunology and treatment of river blindness.. PLoS neglected tropical diseases, 2(4), e217. doi:10.1371/journal.pntd.0000217
2007
Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline.
Nfon, C. K., Makepeace, B. L., Njongmeta, L. M., Tanya, V. N., & Trees, A. J. (2007). Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline.. The American journal of tropical medicine and hygiene, 76(1), 67-72. doi:10.4269/ajtmh.2007.76.67
2006
Eosinophils contribute to killing of adult Onchocerca ochengi within onchocercomata following elimination of Wolbachia.
Nfon, C. K., Makepeace, B. L., Njongmeta, L. M., Tanya, V. N., Bain, O., & Trees, A. J. (2006). Eosinophils contribute to killing of adult Onchocerca ochengi within onchocercomata following elimination of Wolbachia.. Microbes and infection, 8(12-13), 2698-2705. doi:10.1016/j.micinf.2006.07.017
In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.
Tchakouté, V. L., Graham, S. P., Jensen, S. A., Makepeace, B. L., Nfon, C. K., Njongmeta, L. M., . . . Trees, A. J. (2006). In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.. Proceedings of the National Academy of Sciences of the United States of America, 103(15), 5971-5976. doi:10.1073/pnas.0601385103
Rate of elimination of Wolbachia pipientis by doxycycline in vitro increases following drug withdrawal.
Makepeace, B. L., Rodgers, L., & Trees, A. J. (2006). Rate of elimination of Wolbachia pipientis by doxycycline in vitro increases following drug withdrawal.. Antimicrobial agents and chemotherapy, 50(3), 922-927. doi:10.1128/aac.50.3.922-927.2006