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2024

HAP-FAST: a feasibility study incorporating qualitative, mechanistic and costing sub-studies alongside a randomised pilot trial comparing chest x-ray to low-dose CT scan and empirical antibiotics to antibiotics guided by the BIOFIRE® FILM ARRAY® pneumonia <i>plus</i> panel in adults with suspected non-ventilator-associated hospital-cquired pneumonia.

Shafiqa, N., Aston, S., Howard, A., Turtle, L., Abrams, S., Young, B., . . . Wootton, D. G. (2024). HAP-FAST: a feasibility study incorporating qualitative, mechanistic and costing sub-studies alongside a randomised pilot trial comparing chest x-ray to low-dose CT scan and empirical antibiotics to antibiotics guided by the BIOFIRE® FILM ARRAY® pneumonia <i>plus</i> panel in adults with suspected non-ventilator-associated hospital-cquired pneumonia.. BMJ open, 14(7), e088490. doi:10.1136/bmjopen-2024-088490

DOI
10.1136/bmjopen-2024-088490
Journal article

2023

Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial.

Flohr, C., Rosala-Hallas, A., Jones, A. P., Beattie, P., Baron, S., Browne, F., . . . TREAT Trial Investigators. (2023). Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial.. The British journal of dermatology, 189(6), 674-684. doi:10.1093/bjd/ljad281

DOI
10.1093/bjd/ljad281
Journal article

2022

Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop

Rosala-Hallas, A., Jones, A. P., Williamson, P. R., Bedson, E., Compton, V., Fernandes, R. M., . . . McNamara, P. S. (2022). Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop. BMJ Open, 12(3), e052943. doi:10.1136/bmjopen-2021-052943

DOI
10.1136/bmjopen-2021-052943
Journal article

2021

Optimal outcome measures for a trial of not routinely measuring gastric residual volume in neonatal care: a mixed methods consensus process

Gale, C., Dorling, J., Arch, B., Woolfall, K., Deja, E., Roper, L., . . . Tume, L. (2021). Optimal outcome measures for a trial of not routinely measuring gastric residual volume in neonatal care: a mixed methods consensus process. ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 106(3), F292-F297. doi:10.1136/archdischild-2020-319469

DOI
10.1136/archdischild-2020-319469
Journal article

Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol

Setiabudi, W., Hungerford, D., Subramaniam, K., Vaselli, N. M., Shaw, V. E., Wilton, M., . . . French, N. (2021). Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol. BMJ Open, 11(3), e048317. doi:10.1136/bmjopen-2020-048317

DOI
10.1136/bmjopen-2020-048317
Journal article

Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and <i>Pseudomonas</i> <i>aeruginosa</i> infection: the TORPEDO-CF RCT

Hewer, S. C. L., Smyth, A. R., Brown, M., Jones, A. P., Hickey, H., Kenna, D., . . . Williamson, P. R. (2021). Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and <i>Pseudomonas</i> <i>aeruginosa</i> infection: the TORPEDO-CF RCT. HEALTH TECHNOLOGY ASSESSMENT, 25(65), 1-+. doi:10.3310/hta25650

DOI
10.3310/hta25650
Journal article

2020

Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial

Hewer, S. C. L., Smyth, A. R., Brown, M., Jones, A. P., Hickey, H., Kenna, D., . . . Grp, T. O. R. P. E. D. O. -C. F. S. (2020). Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial. LANCET RESPIRATORY MEDICINE, 8(10), 975-986. doi:10.1016/S2213-2600(20)30331-3

DOI
10.1016/S2213-2600(20)30331-3
Journal article

A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis (vol 10, 1796, 2020)

McWilliam, S. J., Rosala-Hallas, A., Jones, A. P., Shaw, V., Greenhalf, W., Jaki, T., . . . Pirmohamed, M. (2020). A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis (vol 10, 1796, 2020). SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-61783-9

DOI
10.1038/s41598-020-61783-9
Journal article

Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial

Ramanan, A. V., Dick, A. D., Guly, C., McKay, A., Jones, A. P., Hardwick, B., . . . APTITUDE Trial Management Group. (2020). Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial. The Lancet Rheumatology, 2(3), e135-e141. doi:10.1016/s2665-9913(20)30008-4

DOI
10.1016/s2665-9913(20)30008-4
Journal article

A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis.

McWilliam, S. J., Rosala-Hallas, A., Jones, A. P., Shaw, V., Greenhalf, W., Jaki, T., . . . Pirmohamed, M. (2020). A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis.. Scientific reports, 10(1). doi:10.1038/s41598-020-58790-1

DOI
10.1038/s41598-020-58790-1
Journal article

Different corticosteroid induction regimens in children and young people with juvenile idiopathic arthritis: the SIRJIA mixed-methods feasibility study.

Jones, A. P., Clayton, D., Nkhoma, G., Sherratt, F. C., Peak, M., Stones, S. R., . . . Baildam, E. M. (2020). Different corticosteroid induction regimens in children and young people with juvenile idiopathic arthritis: the SIRJIA mixed-methods feasibility study.. Health Technology Assessment, 24(36), 1-152. doi:10.3310/hta24360

DOI
10.3310/hta24360
Journal article

2019

Adalimumab in juvenile-idiopathic arthritis-associated uveitis (JIA-U): 5-year follow-up of the Bristol participants of the SYCAMORE trial.

Horton, S., Jones, A. P., Guly, C. M., Hardwick, B., Beresford, M. W., Lee, R. W. J., . . . Ramanan, A. V. (2019). Adalimumab in juvenile-idiopathic arthritis-associated uveitis (JIA-U): 5-year follow-up of the Bristol participants of the SYCAMORE trial.. American journal of ophthalmology. doi:10.1016/j.ajo.2019.06.007

DOI
10.1016/j.ajo.2019.06.007
Journal article

Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO

Ramanan, A. V., Hampson, L. V., Lythgoe, H., Jones, A. P., Hardwick, B., Hind, H., . . . Beresford, M. W. (2019). Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO. PLOS ONE, 14(6). doi:10.1371/journal.pone.0215739

DOI
10.1371/journal.pone.0215739
Journal article

2018

A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT)

Irvine, A. D., Jones, A. P., Beattie, P., Baron, S., Browne, F., Ashoor, F., . . . Flohr, C. (2018). A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT). BRITISH JOURNAL OF DERMATOLOGY, 179(6), 1297-1306. doi:10.1111/bjd.16717

DOI
10.1111/bjd.16717
Journal article

Interventions for helping people recognise early signs of recurrence in depression

Morriss, R. K., Bolton, C. A., McCarthy, J. P., Marshall, M., Williamson, P. R., & Jones, A. P. (n.d.). Interventions for helping people recognise early signs of recurrence in depression. Cochrane Database of Systematic Reviews. doi:10.1002/14651858.cd004855.pub2

DOI
10.1002/14651858.cd004855.pub2
Journal article

A phase II trial protocol of Tocilizumab in anti-TNF refractory patients with JIA-associated uveitis (the APTITUDE trial)

Ramanan, A. V., Dick, A. D., Jones, A. P., Guly, C., Hardwick, B., Hickey, H., . . . Beresford, M. W. (2018). A phase II trial protocol of Tocilizumab in anti-TNF refractory patients with JIA-associated uveitis (the APTITUDE trial). BMC RHEUMATOLOGY, 2(1). doi:10.1186/s41927-018-0010-2

DOI
10.1186/s41927-018-0010-2
Journal article

2017

2016

2014

Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit

Smith, C. T., Williamson, P., Jones, A., Smyth, A., Hewer, S. L., & Gamble, C. (2014). Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit. TRIALS, 15. doi:10.1186/1745-6215-15-127

DOI
10.1186/1745-6215-15-127
Journal article

A Randomised Controlled Trial of the Clinical Effectiveness, Safety and Cost-Effectiveness of Adalimumab in Combination with Methotrexate for the Treatment of Juvenile Idiopathic Arthritis Associated Uveitis

Ramanan, A. V., Dick, A. D., McKay, A., Jones, A., Williamson, P., Compeyrot-Lacassagne, S., . . . Beresford, M. W. (2015). A Randomised Controlled Trial of the Clinical Effectiveness, Safety and Cost-Effectiveness of Adalimumab in Combination with Methotrexate for the Treatment of Juvenile Idiopathic Arthritis Associated Uveitis. ARTHRITIS & RHEUMATOLOGY, 67. Retrieved from https://www.webofscience.com/

Journal article

A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)

Ramanan, A. V., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., . . . The SYCAMORE Trial Management Group. (2014). A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial). Trials, 15. doi:10.1186/1745-6215-15-14

DOI
10.1186/1745-6215-15-14
Journal article

Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit.

Tudur Smith, C., Williamson, P., Jones, A., Smyth, A., Hewer, S. L., & Gamble, C. (2014). Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit.. Trials, 16(15), 127.

Journal article

2013

The use of systematic reviews in the planning,design and condut of randomised trials

Jones, A. P. (2013). The use of systematic reviews in the planning,design and condut of randomised trials [Public Performance].

Performance

2012

Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial

Gringras, P., Gamble, C., Jones, A. P., Wiggs, L., Williamson, P. R., Sutcliffe, A., . . . Appleton, R. (2012). Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial. BRITISH MEDICAL JOURNAL, 345. doi:10.1136/bmj.e6664

DOI
10.1136/bmj.e6664
Journal article

The use of MElatonin in children with Neurodevelopmental Disorders and impaired Sleep: a randomised, double-blind, placebo-controlled, parallel study (MENDS)

Appleton, R. E., Jones, A. P., Gamble, C., Williamson, P. R., Wiggs, L., Montgomery, P., . . . Gringras, P. (2012). The use of MElatonin in children with Neurodevelopmental Disorders and impaired Sleep: a randomised, double-blind, placebo-controlled, parallel study (MENDS). HEALTH TECHNOLOGY ASSESSMENT, 16(40), 1-+. doi:10.3310/hta16400

DOI
10.3310/hta16400
Journal article

The use of Melatonin in chidlren with Neurodevelopmental Disorders and impaired Sleep: a randomised double-blind, placebo-controlled, paralell study (MENDS)

Appleton, R. E., Jones, A. P., Gamble, C., Williamson, P. R., Wiggs, L., Montgomery, P., . . . Gringras, P. (2012). The use of Melatonin in chidlren with Neurodevelopmental Disorders and impaired Sleep: a randomised double-blind, placebo-controlled, paralell study (MENDS). HTA, 16(40).

Journal article

2011

The use of the 5-year-olds' index: comparison between study models and intraoral photographs.

McAuliffe, N. J., Jones, A. P., Cumberbirch, V. C., & Russell, J. I. (2011). The use of the 5-year-olds' index: comparison between study models and intraoral photographs.. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 48(5), 526-531. doi:10.1597/09-265

DOI
10.1597/09-265
Journal article

The use of Systematic reviews in the design of randomised controlled trials

Jones, A. P., Williamson, P. R., Clarke, M., & Gamble, C. (2011). The use of Systematic reviews in the design of randomised controlled trials. In MRC North West Hub for Trials Methodology Research 'Showcase Meeting' Vol. -. Liverpool: -.

Conference Paper

The use of Systematic reviews in the design of randomised controlled trials

Jones, A. P., Williamson, P. R., Clarke, M., & Gamble, C. (2011). The use of Systematic reviews in the design of randomised controlled trials. In Clinical Trials Methodology conference Vol. -. -: MRC Network of HUBS for trials methodology Research.

Conference Paper

2010

Dornase alfa for cystic fibrosis.

Jones, A. P., & Wallis, C. (2010). Dornase alfa for cystic fibrosis.. The Cochrane database of systematic reviews, (3), CD001127. doi:10.1002/14651858.cd001127.pub2

DOI
10.1002/14651858.cd001127.pub2
Journal article

Feasibility study to inform the design of a randomised controlled trial to eradicate <i>Pseudomonas aeruginosa</i> infection in individuals with Cystic Fibrosis

Hickey, H. R., Jones, A. P., Lenney, W., Williamson, P. R., & Smyth, R. L. (2010). Feasibility study to inform the design of a randomised controlled trial to eradicate <i>Pseudomonas aeruginosa</i> infection in individuals with Cystic Fibrosis. TRIALS, 11. doi:10.1186/1745-6215-11-11

DOI
10.1186/1745-6215-11-11
Journal article

2009

Erratum

Erratum (2009). Clinical Trials, 6(3), 288. doi:10.1177/1740774509339555

DOI
10.1177/1740774509339555
Journal article

Meta-analysis of individual patient data versus aggregate data from longitudinal clinical trials

Jones, A. P., Riley, R. D., Williamson, P. R., & Whitehead, A. (2009). Meta-analysis of individual patient data versus aggregate data from longitudinal clinical trials. CLINICAL TRIALS, 6(1), 16-27. doi:10.1177/1740774508100984

DOI
10.1177/1740774508100984
Journal article

2008

Can Western developmental screening tools be modified for use in a rural Malawian setting?

Gladstone, M. J., Lancaster, G. A., Jones, A. P., Maleta, K., Mtitimila, E., Ashorn, P., & Smyth, R. L. (2008). Can Western developmental screening tools be modified for use in a rural Malawian setting?. ARCHIVES OF DISEASE IN CHILDHOOD, 93(1), 23-29. doi:10.1136/adc.2006.095471

DOI
10.1136/adc.2006.095471
Journal article

2007

Non-invasive ventilation for cystic fibrosis.

Moran, F., Bradley, J. M., Jones, A. P., & Piper, A. J. (2007). Non-invasive ventilation for cystic fibrosis.. The Cochrane database of systematic reviews, (4), CD002769. doi:10.1002/14651858.cd002769.pub2

DOI
10.1002/14651858.cd002769.pub2
Journal article

Interventions for helping people recognise early signs of recurrence in bipolar disorder

Morriss, R. K., Faizal, M. A., Jones, A. P., Williamson, P. R., Bolton, C., & McCarthy, J. P. (2007). Interventions for helping people recognise early signs of recurrence in bipolar disorder. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (1). doi:10.1002/14651858.CD004854.pub2

DOI
10.1002/14651858.CD004854.pub2
Journal article

Adalimumab, etanercept and infliximab for the treatment of ankylosing spondylitis: a systematic review and economic evaluation

McLeod, C., Bagust, A., Boland, A., Dagenais, P., Dickson, R., Dundar, Y., . . . Walley, T. (2007). Adalimumab, etanercept and infliximab for the treatment of ankylosing spondylitis: a systematic review and economic evaluation. Unknown Journal, 1-158.

Journal article

Adalimumab, etanercept and infliximab for the treatment of ankylosing spondylitis: a systematic review and economic evaluation.

McLeod, C., Bagust, A., Boland, A., Dagenais, P., Dickson, R., Dundar, Y., . . . Walley, T. (2007). Adalimumab, etanercept and infliximab for the treatment of ankylosing spondylitis: a systematic review and economic evaluation.. Health technology assessment (Winchester, England), 11(28), 1-iv. doi:10.3310/hta11280

DOI
10.3310/hta11280
Journal article

Deworming drugs for treating soil-transmitted intestinal worms in children: effects on growth and school performance

Taylor-Robinson, D. C., Jones, A. P., & Garner, P. (2007). Deworming drugs for treating soil-transmitted intestinal worms in children: effects on growth and school performance. Cochrane Database of Sytematic reviews, (1).

Journal article

Training patients to recognise and manage early warning signs delays recurrence of bipolar disorder

Morriss, R. K., Faizal, M. A., Jones, A. P., Williamson, P. R., Bolton, C., & McCarthy, J. P. (2007). Training patients to recognise and manage early warning signs delays recurrence of bipolar disorder. Evidence-Based Mental Health, 10, 110.

Journal article

2005

A predominantly anti-inflammatory cytokine profile is associated with disease severity in meningococcal sepsis

Carrol, E. D., Thomson, A. P. J., Jones, A. P., Jeffers, G., & Hart, C. A. (2005). A predominantly anti-inflammatory cytokine profile is associated with disease severity in meningococcal sepsis. INTENSIVE CARE MEDICINE, 31(10), 1415-1419. doi:10.1007/s00134-005-2787-x

DOI
10.1007/s00134-005-2787-x
Journal article

High prevalence but low impact of data extraction and reporting errors were found in Cochrane systematic reviews

Jones, A. P., Remmington, T., Williamson, P. R., Ashby, D., & Smyth, R. L. (2005). High prevalence but low impact of data extraction and reporting errors were found in Cochrane systematic reviews. JOURNAL OF CLINICAL EPIDEMIOLOGY, 58(7), 741-742. doi:10.1016/j.jclinepi.2004.11.024

DOI
10.1016/j.jclinepi.2004.11.024
Journal article

2003

Drug therapies for reducing gastric acidity in people with cystic fibrosis.

Ng, S. M., & Jones, A. P. (2003). Drug therapies for reducing gastric acidity in people with cystic fibrosis.. The Cochrane database of systematic reviews, (2), CD003424. doi:10.1002/14651858.cd003424

DOI
10.1002/14651858.cd003424
Journal article

Recombinant human deoxyribonuclease for cystic fibrosis.

Jones, A. P., & Wallis, C. E. (2003). Recombinant human deoxyribonuclease for cystic fibrosis.. The Cochrane database of systematic reviews, (3), CD001127. doi:10.1002/14651858.cd001127

DOI
10.1002/14651858.cd001127
Journal article