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Dr Aphrodite Vasilaki
BSc, PhD, FHEA

Contact

Vasilaki@liverpool.ac.uk

+44 (0)151 794 9069

Publications

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2024

Does lifelong dietary protein restriction contribute to the early onset of sarcopenia?

Ersoy, U., Altinpinar, A. E., Kanakis, I., Peffers, M. J., Jackson, M., Goljanek-Whysall, K., & Vasilaki, A. (2024). Does lifelong dietary protein restriction contribute to the early onset of sarcopenia?. Free Radical Biology and Medicine, 224, S81-S82. doi:10.1016/j.freeradbiomed.2024.10.177

DOI
10.1016/j.freeradbiomed.2024.10.177
Journal article

Maternal Low-Protein Diet Impairs Skeletal Muscle Development, Inflammatory Responses, and Mitochondrial Function in Offspring: Long-Term Effects on Muscle Ageing

Altinpinar, A. E., Ersoy, U., Alameddine, M., Kanakis, I., Pekovic-Vaughan, V., Goljanek-Whysall, K., & Vasilaki, A. (2024). Maternal Low-Protein Diet Impairs Skeletal Muscle Development, Inflammatory Responses, and Mitochondrial Function in Offspring: Long-Term Effects on Muscle Ageing. Free Radical Biology and Medicine, 224, S104. doi:10.1016/j.freeradbiomed.2024.10.230

DOI
10.1016/j.freeradbiomed.2024.10.230
Journal article

Lifelong effects of maternal low protein diet on skeletal muscle development and ageing in male offsprings

Altinpinar, A. E., Ersoy, U., Alameddine, M., Pekovic-Vaughan, V., Kanakis, I., Whysall, K. G., & Vasilaki, A. (2024). Lifelong effects of maternal low protein diet on skeletal muscle development and ageing in male offsprings. Free Radical Biology and Medicine, 218, 39. doi:10.1016/j.freeradbiomed.2024.04.142

DOI
10.1016/j.freeradbiomed.2024.04.142
Journal article

Defining the most potent osteoinductive culture conditions for MC3T3-E1 cells reveals no implication of oxidative stress or energy metabolism

DOI
10.1101/2024.02.28.582483
Preprint

Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis.

Ersoy, U., Kanakis, I., Alameddine, M., Pedraza-Vazquez, G., Ozanne, S. E., Peffers, M. J., . . . Vasilaki, A. (2024). Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis.. Redox biology, 69, 102980. doi:10.1016/j.redox.2023.102980

DOI
10.1016/j.redox.2023.102980
Journal article

2023

Prolonged dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis

Ersoy, U., Vasilaki, A., Jackson, M., Kanakis, I., Peffers, M. J., & Goljanek-Whysall, K. (2023). Prolonged dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis. Free Radical Biology and Medicine, 208, S65. doi:10.1016/j.freeradbiomed.2023.10.146

DOI
10.1016/j.freeradbiomed.2023.10.146
Journal article

Chapter 6 The effect of maternal and early-life nutrition on redox homeostasis

Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). Chapter 6 The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3

DOI
10.1016/b978-0-443-19247-0.00002-3
Chapter

The effect of maternal and early-life nutrition on redox homeostasis

Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3

DOI
10.1016/b978-0-443-19247-0.00002-3
Chapter

Time-of-day secretome profiling reveals rhythmic ECM secretion and altered circadian ECM remodelling during skeletal muscle ageing

Sutton, E., Sarumi, D., Alamedine, M., Fawcett, S., Carter, A., Topping, A., . . . Vaughan, V. P. (2023). Time-of-day secretome profiling reveals rhythmic ECM secretion and altered circadian ECM remodelling during skeletal muscle ageing. In TISSUE ENGINEERING PART A Vol. 29. Retrieved from https://www.webofscience.com/

Conference Paper

2022

MicroRNAs as central regulators of adult myogenesis and proteostasis loss in skeletal muscle aging

Kanakis, I., Myrtziou, I., Vasilaki, A., & Goljanek-Whysall, K. (2022). MicroRNAs as central regulators of adult myogenesis and proteostasis loss in skeletal muscle aging. In Proteostasis and Proteolysis (pp. 45-55). doi:10.1201/9781003048138-4

DOI
10.1201/9781003048138-4
Chapter

Deletion of <i>Sod1</i> in motor neurons exacerbates age-related changes in axons and NMJs associated with premature muscle atrophy in aging mice

DOI
10.1101/2022.01.27.477840
Preprint

2021

Redox cross talk from motor nerves to skeletal muscle regulates muscle redox homeostasis

Jackson, M. J., Pollock, N., Staunton, C., Hemmings, K., Vasilaki, A., & McArdle, A. (2021). Redox cross talk from motor nerves to skeletal muscle regulates muscle redox homeostasis. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 177. doi:10.1016/j.freeradbiomed.2021.08.047

DOI
10.1016/j.freeradbiomed.2021.08.047
Conference Paper

Micrornas as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging

Kanakis, I., Myrtziou, I., Vasilaki, A., & Goljanek-Whysall, K. (2021). Micrornas as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging. In Proteostasis and Proteolysis (pp. 45-56). CRC Press. doi:10.1201/9781003048138-04

DOI
10.1201/9781003048138-04
Chapter

Editorial: Dysregulated Protein Homeostasis in the Aging Organism

Pfirrmann, T., Chondrogianni, N., Olzscha, H., & Vasilaki, A. (2021). Editorial: Dysregulated Protein Homeostasis in the Aging Organism. FRONTIERS IN MOLECULAR BIOSCIENCES, 8. doi:10.3389/fmolb.2021.788118

DOI
10.3389/fmolb.2021.788118
Journal article

Small-RNA Sequencing Reveals Altered Skeletal Muscle microRNAs and snoRNAs Signatures in Weanling Male Offspring from Mouse Dams Fed a Low Protein Diet during Lactation

Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S. E., . . . Vasilaki, A. (2021). Small-RNA Sequencing Reveals Altered Skeletal Muscle microRNAs and snoRNAs Signatures in Weanling Male Offspring from Mouse Dams Fed a Low Protein Diet during Lactation. CELLS, 10(5). doi:10.3390/cells10051166

DOI
10.3390/cells10051166
Journal article

Neuron specific lack of SOD1 leads to accelerated age-related loss of NMJ structure

Pollock, N., Hemmings, K., Staunton, C. A., Owen, E. D., Scalabrin, M., Vasilaki, A., . . . Jackson, M. J. (2021). Neuron specific lack of SOD1 leads to accelerated age-related loss of NMJ structure. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 165. doi:10.1016/j.freeradbiomed.2020.12.304

DOI
10.1016/j.freeradbiomed.2020.12.304
Conference Paper

Small-RNA sequencing reveals altered skeletal muscle microRNAs and snoRNAs signatures in weanling male offspring from mouse dams fed a low protein diet during lactation

Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S., . . . Vasilaki, A. (2021). Small-RNA sequencing reveals altered skeletal muscle microRNAs and snoRNAs signatures in weanling male offspring from mouse dams fed a low protein diet during lactation. doi:10.1101/2021.02.22.432208

DOI
10.1101/2021.02.22.432208
Journal article

2020

Lack of SOD1 In Neuronal Tissue Affects Neuromuscular Junction Stability in Advanced Age

Pollock, N., Hemmings, K., Staunton, C., Owen, E., MacPherson, P., Vasilaki, A., . . . Jackson, M. (2020). Lack of SOD1 In Neuronal Tissue Affects Neuromuscular Junction Stability in Advanced Age. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 159 (pp. S108-S109). doi:10.1016/j.freeradbiomed.2020.10.275

DOI
10.1016/j.freeradbiomed.2020.10.275
Conference Paper

Low protein diet compromises the recovery of lactation-induced bone loss in female mouse dams with no effects on skeletal muscles

Kanakis, I., Alameddine, M., Scalabrin, M., van ’tHof, R., Ozanne, S., Goljanek-Whysall, K., & Vasilaki, A. (2020). Low protein diet compromises the recovery of lactation-induced bone loss in female mouse dams with no effects on skeletal muscles. Bone Reports, 13, 100685. doi:10.1016/j.bonr.2020.100685

DOI
10.1016/j.bonr.2020.100685
Journal article

Low protein intake during reproduction compromises the recovery of lactation‐induced bone loss in female mouse dams without affecting skeletal muscles

Kanakis, I., Alameddine, M., Scalabrin, M., van't Hof, R. J., Liloglou, T., Ozanne, S. E., . . . Vasilaki, A. (2020). Low protein intake during reproduction compromises the recovery of lactation‐induced bone loss in female mouse dams without affecting skeletal muscles. The FASEB Journal. doi:10.1096/fj.202001131R

DOI
10.1096/fj.202001131R
Journal article

Low protein intake compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles

Kanakis, I., Alameddine, M., Scalabrin, M., van ‘t Hof, R., Liloglou, T., Ozanne, S., . . . Vasilaki, A. (2020). Low protein intake compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles. doi:10.1101/2020.05.02.073759

DOI
10.1101/2020.05.02.073759
Journal article

Altered Redox Signalling in both Muscle and Nerve are Required for Neuromuscular Breakdown

Pollock, N., Hemmings, K., Staunton, C., Owen, E., Scalabrin, M., Macpherson, P., . . . Jackson, M. (2020). Altered Redox Signalling in both Muscle and Nerve are Required for Neuromuscular Breakdown. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.05492

DOI
10.1096/fasebj.2020.34.s1.05492
Conference Paper

Genomic Profiling and Physiological Approaches to Understand Aquaporins and their Role in ROS Signalling within Skeletal Muscle

Staunton, C., Vasilaki, A., McArdle, A., Jackson, M., & Barrett-Jolley, R. (2020). Genomic Profiling and Physiological Approaches to Understand Aquaporins and their Role in ROS Signalling within Skeletal Muscle. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.02026

DOI
10.1096/fasebj.2020.34.s1.02026
Conference Paper

The Contribution of Environment to Impair Re-Innervation in Age-Related Failure of Muscle Regeneration Following

Pollock, N., Owen, E., Staunton, C., Davis, C., Vasilaki, A., Richardson, A., . . . McArdle, A. (2020). The Contribution of Environment to Impair Re-Innervation in Age-Related Failure of Muscle Regeneration Following. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.05784

DOI
10.1096/fasebj.2020.34.s1.05784
Conference Paper

Chapter 34 Oxidative stress in skeletal muscle: Unraveling the potential beneficial and deleterious roles of reactive oxygen species

Jackson, M. J., Pollock, N., Staunton, C. A., Stretton, C., Vasilaki, A., & McArdle, A. (2020). Chapter 34 Oxidative stress in skeletal muscle: Unraveling the potential beneficial and deleterious roles of reactive oxygen species. In Oxidative Stress (pp. 713-733). Elsevier. doi:10.1016/b978-0-12-818606-0.00034-1

DOI
10.1016/b978-0-12-818606-0.00034-1
Chapter

2019

Aquaporin transport of hydrogen peroxide in skeletal muscle

Staunton, C. A., Vasilaki, A., McArdle, A., Jackson, M. J., & Barrett‐Jolley, R. (2019). Aquaporin transport of hydrogen peroxide in skeletal muscle. The FASEB Journal, 33(S1). doi:10.1096/fasebj.2019.33.1_supplement.lb644

DOI
10.1096/fasebj.2019.33.1_supplement.lb644
Journal article

Genomic Profiling using RNAseq to identify key drivers of sarcopenia and motor unit turnover in murine skeletal muscle

Staunton, C. A., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. (2019). Genomic Profiling using RNAseq to identify key drivers of sarcopenia and motor unit turnover in murine skeletal muscle. In FASEB JOURNAL Vol. 33. Retrieved from https://www.webofscience.com/

Conference Paper

Neuromuscular Junction Structure and Redox Status of Skeletal Muscle Fiber: Effect on Schwann Cells

Pollock, N., Scalabrin, M., Staunton, C. A., Vasilaki, A., Van Remmen, H., Richardson, A., . . . Jackson, M. J. (2019). Neuromuscular Junction Structure and Redox Status of Skeletal Muscle Fiber: Effect on Schwann Cells. In FASEB JOURNAL Vol. 33. Retrieved from https://www.webofscience.com/

Conference Paper

Oxidative stress in skeletal muscle: Unraveling the potential beneficial and deleterious roles of reactive oxygen species

Jackson, M. J., Pollock, N., Staunton, C. A., Stretton, C., Vasilaki, A., & McArdle, A. (2020). Oxidative stress in skeletal muscle: Unraveling the potential beneficial and deleterious roles of reactive oxygen species. In OXIDATIVE STRESS: EUSTRESS AND DISTRESS (pp. 713-733). doi:10.1016/B978-0-12-818606-0.00034-1

DOI
10.1016/B978-0-12-818606-0.00034-1
Chapter

Reactive oxygen species in age-related decline of skeletal muscle and the musculoskeletal system

Jackson, M., McArdle, A., Pollock, N., Staunton, C., Stretton, C., & Vasilaki, A. (2019). Reactive oxygen species in age-related decline of skeletal muscle and the musculoskeletal system. In EUROPEAN JOURNAL OF CLINICAL INVESTIGATION Vol. 49 (pp. 46). Retrieved from https://www.webofscience.com/

Conference Paper

2018

Aberrant redox signaling in age-related muscle decline

McArdle, A., Pollock, N., Staunton, C. A., Owen, E., Shigdar, S., Scalabrin, M., . . . Jackson, M. J. (2018). Aberrant redox signaling in age-related muscle decline. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 120 (pp. S13-S14). doi:10.1016/j.freeradbiomed.2018.04.059

DOI
10.1016/j.freeradbiomed.2018.04.059
Conference Paper

Redox responses to denervation in skeletal muscle

Scalabrin, M., Pollock, N., McArdle, A., Jackson, M. J., & Vasilaki, A. (2018). Redox responses to denervation in skeletal muscle. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 120 (pp. S36). doi:10.1016/j.freeradbiomed.2018.04.122

DOI
10.1016/j.freeradbiomed.2018.04.122
Conference Paper

CHARACTERISATION OF NF‐KB ACTIVATION IN REGENERATING FIBRES OF OLD MICE

Owen, E. D., Pollock, N., Jackson, M. J., Vasilaki, A., & McArdle, A. (2018). CHARACTERISATION OF NF‐KB ACTIVATION IN REGENERATING FIBRES OF OLD MICE. The FASEB Journal, 32(S1). doi:10.1096/fasebj.2018.32.1_supplement.907.5

DOI
10.1096/fasebj.2018.32.1_supplement.907.5
Journal article

Do senescent cells drive the ageing phenotype of skeletal muscle in vivo?

Shigdar, S., Staunton, C., Vasilaki, A., & McArdle, A. (2018). Do senescent cells drive the ageing phenotype of skeletal muscle in vivo?. The FASEB Journal, 32(S1). doi:10.1096/fasebj.2018.32.1_supplement.907.3

DOI
10.1096/fasebj.2018.32.1_supplement.907.3
Journal article

EFFECT OF DENERVATION ON REDOX‐REGULATION IN SKELETAL MUSCLE

Scalabrin, M., Pollock, N., McArdle, A., Jackson, M. J., & Vasilaki, A. (2018). EFFECT OF DENERVATION ON REDOX‐REGULATION IN SKELETAL MUSCLE. The FASEB Journal, 32(S1). doi:10.1096/fasebj.2018.32.1_supplement.907.1

DOI
10.1096/fasebj.2018.32.1_supplement.907.1
Journal article

Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring

Vasilaki, A., Kanakis, I., Giakoumaki, I., Pollock, N., McArdle, A., Sayer, A. A., & Whysall, K. (2018). Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring. The FASEB Journal, 32(S1). doi:10.1096/fasebj.2018.32.1_supplement.907.6

DOI
10.1096/fasebj.2018.32.1_supplement.907.6
Journal article

Novel intravital assessment of muscle cytosol H<sub>2</sub>0<sub>2</sub> content supports a key role for motor unit remodelling in sarcopenia.

Staunton, C. A., Vasilaki, A., Barrett‐Jolley, R., McArdle, A., & Jackson, M. J. (2018). Novel intravital assessment of muscle cytosol H<sub>2</sub>0<sub>2</sub> content supports a key role for motor unit remodelling in sarcopenia.. The FASEB Journal, 32(S1). doi:10.1096/fasebj.2018.32.1_supplement.907.4

DOI
10.1096/fasebj.2018.32.1_supplement.907.4
Journal article

Senescence in Myoblasts; Role in Age‐Related Muscle Dysfunction

Shigdar, S., Staunton, C., Vasilaki, A., & McArdle, A. (2018). Senescence in Myoblasts; Role in Age‐Related Muscle Dysfunction. The FASEB Journal, 32(S1). doi:10.1096/fasebj.2018.32.1_supplement.907.2

DOI
10.1096/fasebj.2018.32.1_supplement.907.2
Journal article

Comparison of whole body SOD1 knockout with muscle specific SOD1 knockout mice reveals a role for nerve redox signaling in regulation of degenerative pathways in skeletal muscle.

Sakellariou, G. K., McDonagh, B., Porter, H., Giakoumaki, I. I., Earl, K. E., Nye, G. A., . . . Jackson, M. J. (2018). Comparison of whole body SOD1 knockout with muscle specific SOD1 knockout mice reveals a role for nerve redox signaling in regulation of degenerative pathways in skeletal muscle.. Antioxidants and Redox Signaling, 28(4), 275-295. doi:10.1089/ars.2017.7249

DOI
10.1089/ars.2017.7249
Journal article

CHARACTERISATION OF NF-KB ACTIVATION IN REGENERATING FIBRES OF OLD MICE

Owen, E. D., Pollock, N., Jackson, M. J., Vasilaki, A., & McArdle, A. (2018). CHARACTERISATION OF NF-KB ACTIVATION IN REGENERATING FIBRES OF OLD MICE. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/

Conference Paper

Do senescent cells drive the ageing phenotype of skeletal muscle in vivo?

Shigdar, S., Staunton, C., Vasilaki, A., & McArdle, A. (2018). Do senescent cells drive the ageing phenotype of skeletal muscle in vivo?. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/

Conference Paper

EFFECT OF DENERVATION ON REDOX-REGULATION IN SKELETAL MUSCLE

Scalabrin, M., Pollock, N., McArdle, A., Jackson, M. J., & Vasilaki, A. (2018). EFFECT OF DENERVATION ON REDOX-REGULATION IN SKELETAL MUSCLE. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/

Conference Paper

Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring

Vasilaki, A., Kanakis, I., Giakoumaki, I., Pollock, N., McArdle, A., Sayer, A. A., & Whysall, K. (2018). Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/

Conference Paper

Novel intravital assessment of muscle cytosol H<sub>2</sub>0<sub>2</sub> content supports a key role for motor unit remodelling in sarcopenia.

Staunton, C. A., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. J. (2018). Novel intravital assessment of muscle cytosol H<sub>2</sub>0<sub>2</sub> content supports a key role for motor unit remodelling in sarcopenia.. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/

Conference Paper

Senescence in Myoblasts; Role in Age-Related Muscle Dysfunction

Shigdar, S., Staunton, C., Vasilaki, A., & McArdle, A. (2018). Senescence in Myoblasts; Role in Age-Related Muscle Dysfunction. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/

Conference Paper

2017

NRF2/KEAP1-mediated antioxidant defence pathway regulates skeletal muscle circadian clock function

Horton, N. S., Copple, I. M., Vasilaki, A., Jackson, M. J., McArdle, A., & Pekovic-Vaughan, V. (2017). NRF2/KEAP1-mediated antioxidant defence pathway regulates skeletal muscle circadian clock function. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 108 (pp. S48). doi:10.1016/j.freeradbiomed.2017.04.174

DOI
10.1016/j.freeradbiomed.2017.04.174
Conference Paper

Neuromuscular regeneration following whole muscle transplantation

Pollock, N., Davis, C. S., Hassett, C. A., Staunton, C. A., Vasilaki, A., Jackson, M. J., . . . McArdle, A. (2017). Neuromuscular regeneration following whole muscle transplantation. In FASEB JOURNAL Vol. 31. Retrieved from https://www.webofscience.com/

Conference Paper

The role of hydrogen peroxide production in skeletal muscle dysfunction following nerve crush.

Staunton, C. A., Pollock, N., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. J. (2017). The role of hydrogen peroxide production in skeletal muscle dysfunction following nerve crush.. In FASEB JOURNAL Vol. 31. Retrieved from https://www.webofscience.com/

Conference Paper

2016

Effect of Partial Denervation on Mitochondrial ROS Generation in Skeletal Muscle; a Role in Sarcopenia?

Pollock, N., Staunton, C. A., Vasilaki, A., McArdle, A., & Jackson, M. J. (2016). Effect of Partial Denervation on Mitochondrial ROS Generation in Skeletal Muscle; a Role in Sarcopenia?. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 100 (pp. S86-S87). doi:10.1016/j.freeradbiomed.2016.10.216

DOI
10.1016/j.freeradbiomed.2016.10.216
Conference Paper

The Role of Denervation in Cytokine-Mediated Muscle Dysfunction in Old Mice

Staunton, C. A., Pollock, N., McCormick, R., Vasilaki, A., Barrett-Jolley, R., Jackson, M., & McArdle, A. (2016). The Role of Denervation in Cytokine-Mediated Muscle Dysfunction in Old Mice. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 100 (pp. S89). doi:10.1016/j.freeradbiomed.2016.10.222

DOI
10.1016/j.freeradbiomed.2016.10.222
Conference Paper

Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy

Sakellariou, G. K., Pearson, T., Lightfoot, A. P., Nye, G. A., Wells, N., Giakoumaki, I. I., . . . McArdle, A. (2016). Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy. Scientific Reports, 6. doi:10.1038/srep33944

DOI
10.1038/srep33944
Journal article

Cellular mechanisms underlying oxidative stress in human exercise

Jackson, M. J., Vasilaki, A., & McArdle, A. (2016). Cellular mechanisms underlying oxidative stress in human exercise. FREE RADICAL BIOLOGY AND MEDICINE, 98, 13-17. doi:10.1016/j.freeradbiomed.2016.02.023

DOI
10.1016/j.freeradbiomed.2016.02.023
Journal article

Ageing in relation to skeletal muscle dysfunction: redox homoeostasis to regulation of gene expression

Goljanek-Whysall, K., Iwanejko, L. A., Vasilaki, A., Pekovic-Vaughan, V., & McDonagh, B. (2016). Ageing in relation to skeletal muscle dysfunction: redox homoeostasis to regulation of gene expression. MAMMALIAN GENOME, 27(7-8), 341-357. doi:10.1007/s00335-016-9643-x

DOI
10.1007/s00335-016-9643-x
Journal article

Age-related neuromuscular deficits in reactive oxygen species generation in exercising skeletal muscle

Jackson, M. J., Vasilaki, A., Pollock, N., Staunton, C., McDonagh, B., & McArdle, A. (2016). Age-related neuromuscular deficits in reactive oxygen species generation in exercising skeletal muscle. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 96 (pp. S13). doi:10.1016/j.freeradbiomed.2016.04.059

DOI
10.1016/j.freeradbiomed.2016.04.059
Conference Paper

Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage

McDonagh, B., Scullion, S. M., Vasilaki, A., Pollock, N., McArdle, A., & Jackson, M. J. (2016). Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage. Free Radical Biology and Medicine, 94, 27-35. doi:10.1016/j.freeradbiomed.2016.02.008

DOI
10.1016/j.freeradbiomed.2016.02.008
Journal article

Effect of partial denervation mitochondrial ROS generation in skeletal muscle

Pollock, N., Staunton, C. A., Vasilaki, A., McArdle, A., & Jackson, M. (2016). Effect of partial denervation mitochondrial ROS generation in skeletal muscle. In FASEB JOURNAL Vol. 30. Retrieved from https://www.webofscience.com/

Conference Paper

Maternal protein intake as a determinant of the total number of motor units and muscle fibres in mice

Vasilaki, A., Glakoumaki, I., Pollock, N., Goljanek-Whysall, K., McArdle, A., & Sayer, A. A. (2016). Maternal protein intake as a determinant of the total number of motor units and muscle fibres in mice. In FASEB JOURNAL Vol. 30. Retrieved from https://www.webofscience.com/

Conference Paper

The role of denervation in cytokine-mediated muscle dysfunction in muscles of old mice

Staunton, C. A., Pollock, N., Lightfoot, A., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. (2016). The role of denervation in cytokine-mediated muscle dysfunction in muscles of old mice. In FASEB JOURNAL Vol. 30. Retrieved from https://www.webofscience.com/

Conference Paper

2015

Manipulation of Environmental Oxygen Modifies Reactive Oxygen Species Generation during Myogenesis

McCormick, R., McArdle, A., Jackson, M., & Vasilaki, A. (2015). Manipulation of Environmental Oxygen Modifies Reactive Oxygen Species Generation during Myogenesis. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 86 (pp. S39-S40). doi:10.1016/j.freeradbiomed.2015.07.137

DOI
10.1016/j.freeradbiomed.2015.07.137
Conference Paper

<i>In vivo</i> Studies of Motor Nerve Re‐growth in Adult and Old Mice Following Contraction‐induced Injury

Vasilaki, A., Sakellariou, G., Kayani, A., Jackson, M., & McArdle, A. (2015). <i>In vivo</i> Studies of Motor Nerve Re‐growth in Adult and Old Mice Following Contraction‐induced Injury. The FASEB Journal, 29(S1). doi:10.1096/fasebj.29.1_supplement.1055.29

DOI
10.1096/fasebj.29.1_supplement.1055.29
Journal article

Does Manipulation of Environmental Oxygen Modify Reactive Oxygen (ROS) Species Generation During Myogenesis?

McCormick, R., Jackson, M., McArdle, A., & Vasilaki, A. (2015). Does Manipulation of Environmental Oxygen Modify Reactive Oxygen (ROS) Species Generation During Myogenesis?. In FASEB JOURNAL Vol. 29. Retrieved from https://www.webofscience.com/

Conference Paper

Effect of Muscle Fiber Denervation on Mitochondrial Hydrogen Peroxide Generation in Adjacent Innervated Muscle Fibres: Role in Sarcopenia?

Pollock, N., Vasilaki, A., McArdle, A., & Jackson, M. (2015). Effect of Muscle Fiber Denervation on Mitochondrial Hydrogen Peroxide Generation in Adjacent Innervated Muscle Fibres: Role in Sarcopenia?. In FASEB JOURNAL Vol. 29. Retrieved from https://www.webofscience.com/

Conference Paper

Effect of Resveratrol on Chemokine Induced Atrophy

McCormick, R., Ford, C., Jackson, M., McArdle, A., & Vasilaki, A. (2015). Effect of Resveratrol on Chemokine Induced Atrophy. In FASEB JOURNAL Vol. 29. Retrieved from https://www.webofscience.com/

Conference Paper

<i>In vivo</i> Studies of Motor Nerve Re-growth in Adult and Old Mice Following Contraction-induced Injury

Vasilaki, A., Sakellariou, G., Kayani, A., Jackson, M., & McArdle, A. (2015). <i>In vivo</i> Studies of Motor Nerve Re-growth in Adult and Old Mice Following Contraction-induced Injury. In FASEB JOURNAL Vol. 29. Retrieved from https://www.webofscience.com/

Conference Paper

2014

Redox and epigenetic regulation of the APE1 gene in the hippocampus of piglets: The effect of early life exposures

Langie, S. A. S., Kowalczyk, P., Tomaszewski, B., Vasilaki, A., Maas, L. M., Moonen, E. J., . . . Mathers, J. C. (2014). Redox and epigenetic regulation of the APE1 gene in the hippocampus of piglets: The effect of early life exposures. DNA Repair, 18, 52-62. doi:10.1016/j.dnarep.2014.03.011

DOI
10.1016/j.dnarep.2014.03.011
Journal article

NF‐κB activation in hindlimb muscles from adult and old mice at rest and following contractile activity (LB814)

Pollock, N., Vasilaki, A., Lightfoot, A., Jackson, M., & McArdle, A. (2014). NF‐κB activation in hindlimb muscles from adult and old mice at rest and following contractile activity (LB814). The FASEB Journal, 28(S1). doi:10.1096/fasebj.28.1_supplement.lb814

DOI
10.1096/fasebj.28.1_supplement.lb814
Journal article

Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice.

Sakellariou, G. K., Davis, C. S., Shi, Y., Ivannikov, M. V., Zhang, Y., Vasilaki, A., . . . Brooks, S. V. (2014). Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice.. The FASEB Journal, 28(4), 1666-1681. doi:10.1096/fj.13-240390

DOI
10.1096/fj.13-240390
Journal article

Neuron‐specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD knockout mice (1153.3)

Sakellariou, G., Davis, C., Shi, Y., Ivannikov, M., Zhang, Y., Giakoumaki, I., . . . Brooks, S. (2014). Neuron‐specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD knockout mice (1153.3). The FASEB Journal, 28(S1). doi:10.1096/fasebj.28.1_supplement.1153.3

DOI
10.1096/fasebj.28.1_supplement.1153.3
Journal article

Redefining the major contributors to superoxide production in contracting skeletal muscle. The role of NAD(P)H oxidases

Sakellariou, G. K., Jackson, M. J., & Vasilaki, A. (2014). Redefining the major contributors to superoxide production in contracting skeletal muscle. The role of NAD(P)H oxidases. Free Radical Research, 48(1), 12-29. doi:10.3109/10715762.2013.830718

DOI
10.3109/10715762.2013.830718
Journal article

Redefining the major contributors to superoxide production in contracting skeletal muscle. The role of NAD(P)H oxidases

Sakellariou, G. K., Jackson, M. J., & Vasilaki, A. (2014). Redefining the major contributors to superoxide production in contracting skeletal muscle. The role of NAD(P)H oxidases. FREE RADICAL RESEARCH, 48(1), 12-29. doi:10.3109/10715762.2013.830718

DOI
10.3109/10715762.2013.830718
Journal article

2013

Accelerated age-related loss of muscle mass in homozygotic SOD1 knockout mice is not associated with neuronal oxidative damage

Sakellariou, G. K., Lightfoot, A. P., Vasilaki, A., Nye, G., Van Remmen, H., Brooks, S., . . . Jackson, M. J. (2013). Accelerated age-related loss of muscle mass in homozygotic SOD1 knockout mice is not associated with neuronal oxidative damage. FREE RADICAL BIOLOGY AND MEDICINE, 65, S48. doi:10.1016/j.freeradbiomed.2013.08.077

DOI
10.1016/j.freeradbiomed.2013.08.077
Journal article

Are age-related changes in redox biology important contributors to weakness in old age?

Jacksonn, M. J., Vasilaki, A., Pearson, T., Sakellariou, G., Scullion, S., Ford, C., . . . Cardle, A. M. (2013). Are age-related changes in redox biology important contributors to weakness in old age?. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 65 (pp. S1). doi:10.1016/j.freeradbiomed.2013.08.101

DOI
10.1016/j.freeradbiomed.2013.08.101
Conference Paper

Does manipulation of environmental oxygen modify the Reactive Oxygen Species generation during myogenesis?

Vasilaki, A., McCormick, R., McArdle, A., & Jackson, M. J. (2013). Does manipulation of environmental oxygen modify the Reactive Oxygen Species generation during myogenesis?. FREE RADICAL BIOLOGY AND MEDICINE, 65, S53. doi:10.1016/j.freeradbiomed.2013.08.091

DOI
10.1016/j.freeradbiomed.2013.08.091
Journal article

Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions

Palomero, J., Vasilaki, A., Pye, D., McArdle, A., & Jackson, M. J. (2013). Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 305(4), R351-R358. doi:10.1152/ajpregu.00530.2012

DOI
10.1152/ajpregu.00530.2012
Journal article

Role of reactive oxygen species in the defective regeneration seen in aging muscle

Vasilaki, A., & Jackson, M. J. (2013). Role of reactive oxygen species in the defective regeneration seen in aging muscle. FREE RADICAL BIOLOGY AND MEDICINE, 65, 317-323. doi:10.1016/j.freeradbiomed.2013.07.008

DOI
10.1016/j.freeradbiomed.2013.07.008
Journal article

Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model

Robinson, S. M., Mann, J., Vasilaki, A., Mathers, J., Burt, A. D., Oakley, F., . . . Mann, D. A. (2013). Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy model. JOURNAL OF HEPATOLOGY, 59(2), 318-326. doi:10.1016/j.jhep.2013.04.014

DOI
10.1016/j.jhep.2013.04.014
Journal article

Adaptive cytoprotective responses of motor neuron cells to reactive oxygen species generation by muscle cells, in co-culture

Scullion, S. M. J., Vasilaki, A., McArdle, A., & Jackson, M. J. (2013). Adaptive cytoprotective responses of motor neuron cells to reactive oxygen species generation by muscle cells, in co-culture. In FASEB JOURNAL Vol. 27. Retrieved from https://www.webofscience.com/

Conference Paper

Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity

Sakellariou, G. K., Vasilaki, A., Palomero, J., Kayani, A., Zibrik, L., McArdle, A., & Jackson, M. J. (2013). Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity. ANTIOXIDANTS & REDOX SIGNALING, 18(6), 603-621. doi:10.1089/ars.2012.4623

DOI
10.1089/ars.2012.4623
Journal article

2012

A transgenic approach to understanding age-related loss of muscle mass and function

McArdle⁎, A., Kayani, A., Vasilaki, A., Sakellariou, G., & Jackson, M. (2012). A transgenic approach to understanding age-related loss of muscle mass and function. Free Radical Biology and Medicine, 53, S261. doi:10.1016/j.freeradbiomed.2012.08.063

DOI
10.1016/j.freeradbiomed.2012.08.063
Journal article

Investigating the intracellular changes in ROS production and adaptive responses in muscle specific SOD1 knockout mice

Sakellariou, G. K., Kayani, A., Vasilaki, A., Scott, A., Van Remmen, H., Brooks, S., . . . Jackson, M. J. (2012). Investigating the intracellular changes in ROS production and adaptive responses in muscle specific SOD1 knockout mice. FREE RADICAL BIOLOGY AND MEDICINE, 53, S53-S54. doi:10.1016/j.freeradbiomed.2012.08.533

DOI
10.1016/j.freeradbiomed.2012.08.533
Journal article

<i>In vivo</i> studies of motor nerve re‐growth following skeletal muscle damage by lengthening contractions

Vasilaki, A., Kayani, A., Pearson, T., McArdle, A., & Jackson, M. (2012). <i>In vivo</i> studies of motor nerve re‐growth following skeletal muscle damage by lengthening contractions. The FASEB Journal, 26(S1). doi:10.1096/fasebj.26.1_supplement.1141.4

DOI
10.1096/fasebj.26.1_supplement.1141.4
Journal article

Studies of mitochondrial and non-mitochondrial sources implicate NADPH oxidase(s) in the increased skeletal muscle superoxide generation that occurs during contractile activity

Sakellariou, G. K., Vasilaki, A., Palomero, J., Kayani, A., Zibrik, L., McArdle, A., & Jackson, M. J. (2012). Studies of mitochondrial and non-mitochondrial sources implicate NADPH oxidase(s) in the increased skeletal muscle superoxide generation that occurs during contractile activity. In FASEB JOURNAL Vol. 26. Retrieved from https://www.webofscience.com/

Conference Paper

Tissue-dependent changes in oxidative damage with male reproductive effort in house mice

Garratt, M., McArdle, F., Stockley, P., Vasilaki, A., Beynon, R. J., Jackson, M. J., & Hurst, J. L. (2012). Tissue-dependent changes in oxidative damage with male reproductive effort in house mice. FUNCTIONAL ECOLOGY, 26(2), 423-433. doi:10.1111/j.1365-2435.2011.01952.x

DOI
10.1111/j.1365-2435.2011.01952.x
Journal article

Tissue dependent changes in oxidative damage with male reproductive effort in house mice

Garratt, M., McArdle, F., Stockley, P., Vasilaki, A., Beynon, R., Jackson, M. J., & Hurst, J. (2012). Tissue dependent changes in oxidative damage with male reproductive effort in house mice. Functional Ecology, 26, 423-433.

Journal article

2011

Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase

Sakellariou, G. K., Pye, D., Vasilaki, A., Zibrik, L., Palomero, J., Kabayo, T., . . . Jackson, M. J. (2011). Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase. AGING CELL, 10(5), 749-760. doi:10.1111/j.1474-9726.2011.00709.x

DOI
10.1111/j.1474-9726.2011.00709.x
Journal article

Role of superoxide–nitric oxide interactions in the accelerated age‐related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase

Sakellariou, G. K., Pye, D., Vasilaki, A., Zibrik, L., Palomero, J., Kabayo, T., . . . Jackson, M. J. (2011). Role of superoxide–nitric oxide interactions in the accelerated age‐related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase. Aging Cell, 10(5), 749-760. doi:10.1111/j.1474-9726.2011.00709.x

DOI
10.1111/j.1474-9726.2011.00709.x
Journal article

Is oxidative stress a physiological cost of reproduction? An experimental test in house mice

Garratt, M., Vasilaki, A., Stockley, P., McArdle, F., Jackson, M., & Hurst, J. L. (2011). Is oxidative stress a physiological cost of reproduction? An experimental test in house mice. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 278(1708), 1098-1106. doi:10.1098/rspb.2010.1818

DOI
10.1098/rspb.2010.1818
Journal article

Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase

Sakellariou, G. K., Pye, D., Vasilaki, A., Zibrik, L., Palomero, J., Kabayo, T., . . . Jackson, M. J. (2011). Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase. Aging Cell, 10, 749-760.

Journal article

2010

The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase

Vasilaki, A., van der Meulen, J. H., Larkin, L., Harrison, D. C., Pearson, T., Van Remmen, H., . . . McArdle, A. (2010). The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. AGING CELL, 9(6), 979-990. doi:10.1111/j.1474-9726.2010.00635.x

DOI
10.1111/j.1474-9726.2010.00635.x
Journal article

The age‐related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase

Vasilaki, A., van der Meulen, J. H., Larkin, L., Harrison, D. C., Pearson, T., Van Remmen, H., . . . McArdle, A. (2010). The age‐related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. Aging Cell, 9(6), 979-990. doi:10.1111/j.1474-9726.2010.00635.x

DOI
10.1111/j.1474-9726.2010.00635.x
Journal article

Role Of The Redox-sensitive Transcription Factor, NFkB In Skeletal Muscle Cells During Differentiation

Vasilaki, A., Douramani, M. T., Jackson, M. J., & McArdle, A. (2010). Role Of The Redox-sensitive Transcription Factor, NFkB In Skeletal Muscle Cells During Differentiation. Medicine &amp; Science in Sports &amp; Exercise, 42(10), 95. doi:10.1249/01.mss.0000389454.09783.63

DOI
10.1249/01.mss.0000389454.09783.63
Journal article

Reactive oxygen species and loss of muscle fibres during ageing

Jackson, M. J., Pearson, T., Vasilaki, A., Sakellariou, G., Palomero, J., & McArdle, A. (2010). Reactive oxygen species and loss of muscle fibres during ageing. In NEUROMUSCULAR DISORDERS Vol. 20 (pp. S3). doi:10.1016/S0960-8966(10)70009-2

DOI
10.1016/S0960-8966(10)70009-2
Conference Paper

2008

Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor κB activation

Brooks, S. V., Vasilaki, A., Larkin, L. M., McArdle, A., & Jackson, M. J. (2008). Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor κB activation. JOURNAL OF PHYSIOLOGY-LONDON, 586(16), 3979-3990. doi:10.1113/jphysiol.2008.155382

DOI
10.1113/jphysiol.2008.155382
Journal article

2007

Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle

Vasilaki, A., Simpson, D., McArdle, F., McLean, L., Beynon, R. J., Van Remmen, H., . . . Jackson, M. J. (2007). Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle. PROTEOMICS CLINICAL APPLICATIONS, 1(4), 362-372. doi:10.1002/prca.200600702

DOI
10.1002/prca.200600702
Journal article

Formation of 3‐nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle

Vasilaki, A., Simpson, D., McArdle, F., McLean, L., Beynon, R. J., Van Remmen, H., . . . Jackson, M. J. (2007). Formation of 3‐nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle. PROTEOMICS – Clinical Applications, 1(4), 362-372. doi:10.1002/prca.200600702

DOI
10.1002/prca.200600702
Journal article

2006

Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells

Vasilaki, A., Csete, M., Pye, D., Lee, S., Palomero, J., McArdle, F., . . . Jackson, M. J. (2006). Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells. FREE RADICAL BIOLOGY AND MEDICINE, 41(11), 1719-1725. doi:10.1016/j.freeradbiomed.2006.09.008

DOI
10.1016/j.freeradbiomed.2006.09.008
Journal article

Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells.

Vasilaki, A., Csete, M., Pye, D., Lee, S., Palomero, J., McArdle, F., . . . Jackson, M. J. (2006). Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells.. Free radical biology & medicine, 41(11), 1719-1725.

Journal article

Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age

Vasilaki, A., McArdle, F., Iwanejko, L. M., & McArdle, A. (2006). Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age. MECHANISMS OF AGEING AND DEVELOPMENT, 127(11), 830-839. doi:10.1016/j.mad.2006.08.004

DOI
10.1016/j.mad.2006.08.004
Journal article

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective.

Lee, S., Shin, H. S., Shireman, P. K., Vasilaki, A., Van Remmen, H., & Csete, M. E. (2006). Glutathione-peroxidase-1 null muscle progenitor cells are globally defective.. Free radical biology & medicine, 41(7), 1174-1184. doi:10.1016/j.freeradbiomed.2006.07.005

DOI
10.1016/j.freeradbiomed.2006.07.005
Journal article

HSF expression in skeletal muscle during myogenesis: Implications for failed regeneration in old mice

McArdle, A., Broome, C. S., Kayani, A. C., Tully, M. D., Close, G. L., Vasilaki, A., & Jackson, M. J. (2006). HSF expression in skeletal muscle during myogenesis: Implications for failed regeneration in old mice. EXPERIMENTAL GERONTOLOGY, 41(5), 497-500. doi:10.1016/j.exger.2006.02.002

DOI
10.1016/j.exger.2006.02.002
Journal article

Free radical generation by skeletal muscle of adult and old mice: effect of contractile activity

Vasilaki, A., Mansouri, A., Van Remmen, H., van der Meulen, J. H., Larkin, L., Richardson, A. G., . . . Jackson, M. J. (2006). Free radical generation by skeletal muscle of adult and old mice: effect of contractile activity. AGING CELL, 5(2), 109-117. doi:10.1111/j.1474-9726.2006.00198.x

DOI
10.1111/j.1474-9726.2006.00198.x
Journal article

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

Lee, S., Shin, H. S., Shireman, P. K., Vasilaki, A., Van Remmen, H., & Csete, M. E. (2006). Glutathione-peroxidase-1 null muscle progenitor cells are globally defective. FREE RADICAL BIOLOGY AND MEDICINE, 41(7), 1174-1184. doi:10.1016/j.freeradbiomed.2006.07.005

DOI
10.1016/j.freeradbiomed.2006.07.005
Journal article

2005

Intracellular generation of reactive oxygen species by contracting skeletal muscle cells

McArdle, F., Pattwell, D. M., Vasilaki, A., McArdle, A., & Jackson, M. J. (2005). Intracellular generation of reactive oxygen species by contracting skeletal muscle cells. FREE RADICAL BIOLOGY AND MEDICINE, 39(5), 651-657. doi:10.1016/j.freeradbiomed.2005.04.010

DOI
10.1016/j.freeradbiomed.2005.04.010
Journal article

Skeletal muscle damage with exercise and aging

Close, G. L., Kayani, A., Vasilaki, A., & McArdle, A. (2005). Skeletal muscle damage with exercise and aging. SPORTS MEDICINE, 35(5), 413-427. doi:10.2165/00007256-200535050-00004

DOI
10.2165/00007256-200535050-00004
Journal article

2004

Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice

McArdle, F., Spiers, S., Aldemir, H., Vasilaki, A., Beaver, A., Iwanejko, L., . . . Jackson, M. J. (2004). Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice. JOURNAL OF PHYSIOLOGY-LONDON, 561(1), 233-244. doi:10.1113/jphysiol.2004.069914

DOI
10.1113/jphysiol.2004.069914
Journal article

Vitamin E and the oxidative stress of exercise

Jackson, M. J., Khassaf, M., Vasilaki, A., McArdle, F., & McArdle, A. (2004). Vitamin E and the oxidative stress of exercise. VITAMIN E AND HEALTH, 1031, 158-168. doi:10.1196/annals.1331.015

DOI
10.1196/annals.1331.015
Journal article

2003

Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle

Khassaf, M., McArdle, A., Esanu, C., Vasilaki, A., McArdle, F., Griffiths, R. D., . . . Jackson, M. J. (2003). Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. JOURNAL OF PHYSIOLOGY-LONDON, 549(2), 645-652. doi:10.1113/jphysiol.2003.040303

DOI
10.1113/jphysiol.2003.040303
Journal article

Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle

Khassaf, M., McArdle, A., Esanu, C., Vasilaki, A., McArdle, F., Griffiths, R. D., . . . Jackson, M. J. (2003). Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. Journal of Physiology, 549(2), 645-652. doi:10.1113/jphysiol.2003.040303

DOI
10.1113/jphysiol.2003.040303
Journal article

Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins

Maglara, A. A., Vasilaki, A., Jackson, M. J., & McArdle, A. (2003). Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins. The Journal of Physiology, 548(3), 837-846. doi:10.1111/j.1469-7793.2003.00837.x

DOI
10.1111/j.1469-7793.2003.00837.x
Journal article

Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins

Maglara, A. A., Vasilaki, A., Jackson, M. J., & McArdle, A. (2003). Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins. JOURNAL OF PHYSIOLOGY-LONDON, 548(3), 837-846. doi:10.1113/jphysiol.2002.034520

DOI
10.1113/jphysiol.2002.034520
Journal article

Skeletal muscles of aged male mice fail to adapt following contractile activity

Vasilaki, A., Iwanejko, L., McArdle, F., Broome, C. S., Jackson, M. J., & McArdle, A. (2003). Skeletal muscles of aged male mice fail to adapt following contractile activity. BIOCHEMICAL SOCIETY TRANSACTIONS, 31, 455-456. doi:10.1042/BST0310455

DOI
10.1042/BST0310455
Journal article

Skeletal Muscle Aging

Broome, C. S., Vasilaki, A., & McArdle, A. (2003). Skeletal Muscle Aging. In Aging of the Organs and Systems (pp. 73-99). Springer Netherlands. doi:10.1007/978-94-017-0673-5_3

DOI
10.1007/978-94-017-0673-5_3
Chapter

2002

Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity

Vasilaki, A., Jackson, M. J., & McArdle, A. (2002). Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity. MUSCLE & NERVE, 25(6), 902-905. doi:10.1002/mus.10094

DOI
10.1002/mus.10094
Journal article

Exercise and skeletal muscle ageing: cellular and molecular mechanisms

McArdle, A., Vasilaki, A., & Jackson, M. (2002). Exercise and skeletal muscle ageing: cellular and molecular mechanisms. AGEING RESEARCH REVIEWS, 1(1), 79-93. doi:10.1016/S0047-6374(01)00368-2

DOI
10.1016/S0047-6374(01)00368-2
Journal article

2001

Contractile activity-induced oxidative stress: cellular origin and adaptive responses

McArdle, A., Pattwell, D., Vasilaki, A., Griffiths, R. D., & Jackson, M. J. (2001). Contractile activity-induced oxidative stress: cellular origin and adaptive responses. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 280(3), C621-C627. doi:10.1152/ajpcell.2001.280.3.C621

DOI
10.1152/ajpcell.2001.280.3.C621
Journal article

Contractile activity-induced oxidative stress: Cellular origin and adaptive responses

McArdle, A., Pattwell, D., Vasilaki, A., Griffiths, R. D., & Jackson, M. J. (2001). Contractile activity-induced oxidative stress: Cellular origin and adaptive responses. American Journal of Physiology - Cell Physiology, 280(3 49-3). doi:10.1152/ajpcell.2001.280.3.c621

DOI
10.1152/ajpcell.2001.280.3.c621
Journal article

Contractile activity-induced oxidative stress: cellular origin and adaptive responses

McArdle, A., Pattwell, D., Vasilaki, A., Griffiths, R. D., & Jackson, M. J. (2001). Contractile activity-induced oxidative stress: cellular origin and adaptive responses. Am J Physiol Cell Physiol, 280(3)(3), C621-C627.

Journal article

2000

HSP Production in Skeletal Muscle of Young and Old Rats following Exercise

Vasilaki, A., Jackson, M. J., & McArdle, A. (2000). HSP Production in Skeletal Muscle of Young and Old Rats following Exercise. Clinical Science, 99(s43), 22P. doi:10.1042/cs099022pa

DOI
10.1042/cs099022pa
Journal article