Publications
2024
Single microRNA panel to detect and predict the severity of acute pancreatitis
Sutton, R., Evans, A., Jones, A., Latawiec, D., Cai, W., Kattakayam, A., . . . Szatmary, P. (2024). Single microRNA panel to detect and predict the severity of acute pancreatitis. Pancreatology, 24, e32-e33. doi:10.1016/j.pan.2024.05.075
Gene Expression Dysregulation in Whole Blood of Patients with Clostridioides difficile Infection
Tsakiroglou, M., Evans, A., Doce-Carracedo, A., Little, M., Hornby, R., Roberts, P., . . . Pirmohamed, M. (n.d.). Gene Expression Dysregulation in Whole Blood of Patients with Clostridioides difficile Infection. International Journal of Molecular Sciences, 25(23), 12653. doi:10.3390/ijms252312653
Data from Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis
Bermejo-Rodriguez, C., Araos Henríquez, J., Caligiuri, G., Pinto Teles, S., Park, Y., Evans, A., . . . Perez-Mancera, P. A. (2024). Data from Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis. doi:10.1158/0008-5472.c.7451265
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.
Bermejo-Rodriguez, C., Araos Henríquez, J., Caligiuri, G., Pinto Teles, S., Park, Y., Evans, A., . . . Perez-Mancera, P. A. (2024). Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.. Cancer research. doi:10.1158/0008-5472.can-23-3419
2023
K-Ras independence due to N-Ras expression in cancer cell lines giving resistance to K-Ras specific inhibitors
Ferguson, R., Aughton, K., Evans, A., Shaw, V., Costello, E., & Greenhalf, W. (2023). K-Ras independence due to N-Ras expression in cancer cell lines giving resistance to K-Ras specific inhibitors. Pancreatology, 23, e149. doi:10.1016/j.pan.2023.06.783
Mutant K-Ras in Pancreatic Cancer: An Insight on the Role of Wild-Type N-Ras and K-Ras-Dependent Cell Cycle Regulation
Ferguson, R., Aughton, K., Evans, A., Shaw, V., Armstrong, J., Ware, A., . . . Greenhalf, W. (2023). Mutant K-Ras in Pancreatic Cancer: An Insight on the Role of Wild-Type N-Ras and K-Ras-Dependent Cell Cycle Regulation. CURRENT ISSUES IN MOLECULAR BIOLOGY, 45(3), 2505-2520. doi:10.3390/cimb45030164
Leveraging transcriptomics for precision diagnosis: Lessons learned from cancer and sepsis
Tsakiroglou, M., Evans, A., & Pirmohamed, M. (2023). Leveraging transcriptomics for precision diagnosis: Lessons learned from cancer and sepsis. FRONTIERS IN GENETICS, 14. doi:10.3389/fgene.2023.1100352
2022
Pancreatic cancer-related diabetes mellitus: a clinical perspective
Stott, M., Oldfield, L., Evans, A., Halloran, C., & Costello, E. (2022). Pancreatic cancer-related diabetes mellitus: a clinical perspective. Pancreatology, 22, e63. doi:10.1016/j.pan.2022.06.164
The Effect of Sampling Methodology upon Pancreatic Cancer Microbiome Communities
Hale, J., Evans, A., Lilley, A., Fine, D., Costello-Goldring, E., Halloran, C., . . . Greenhalf, W. (2022). The Effect of Sampling Methodology upon Pancreatic Cancer Microbiome Communities. Pancreatology, 22, e61. doi:10.1016/j.pan.2022.06.157
Blood levels of adiponectin and IL-1Ra distinguish type 3c from type 2 diabetes: Implications for earlier pancreatic cancer detection in new-onset diabetes
Oldfield, L., Evans, A., Rao, R. G., Jenkinson, C., Purewal, T., Psarelli, E. E., . . . Costello, E. (2022). Blood levels of adiponectin and IL-1Ra distinguish type 3c from type 2 diabetes: Implications for earlier pancreatic cancer detection in new-onset diabetes. EBIOMEDICINE, 75. doi:10.1016/j.ebiom.2021.103802
2021
hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA
Aughton, K., Elander, N. O., Evans, A., Jackson, R., Campbell, F., Costello, E., . . . Greenhalf, W. (2021). hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA. CANCERS, 13(22). doi:10.3390/cancers13225758
The holding temperature of blood during a delay to processing can affect serum and plasma protein measurements
Ashworth, M., Small, B., Oldfield, L., Evans, A., Greenhalf, W., Halloran, C., & Costello, E. (2021). The holding temperature of blood during a delay to processing can affect serum and plasma protein measurements. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-85052-5
2020
Fibroblasts from Distinct Pancreatic Pathologies Exhibit Disease-Specific Properties.
Barrera, L. N., Evans, A., Lane, B., Brumskill, S., Oldfield, F. E., Campbell, F., . . . Costello, E. (2020). Fibroblasts from Distinct Pancreatic Pathologies Exhibit Disease-Specific Properties.. Cancer Research, 80(13), 2861-2873. doi:10.1158/0008-5472.can-19-3534
2019
The human equilibrative nucleoside transporter1 evaluated by SP120 and 10D7G2 had the potential to predict the prognosis in the patients with pancreatic cancer treated with adjuvant gemcitabine: Collaborative study of the JASPAC 01 trial
Okamura, Y., Yasukawa, S., Narimatsu, H., Evans, A., Boku, N., Fukutomi, A., . . . Uesaka, K. (2019). The human equilibrative nucleoside transporter1 evaluated by SP120 and 10D7G2 had the potential to predict the prognosis in the patients with pancreatic cancer treated with adjuvant gemcitabine: Collaborative study of the JASPAC 01 trial. Pancreatology, 19, S106. doi:10.1016/j.pan.2019.05.282
2018
S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes
Nedjadi, T., Evans, A., Sheikh, A., Barerra, L., Al-Ghamdi, S., Oldfield, L., . . . Costello, E. (2018). S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes. BMC CANCER, 18. doi:10.1186/s12885-018-5161-4
F<sub>1</sub>F<sub>0</sub>-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation
Tanton, H., Voronina, S., Evans, A., Armstrong, J., Sutton, R., Criddle, D. N., . . . Tepikin, A. V. (2018). F<sub>1</sub>F<sub>0</sub>-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation. FRONTIERS IN PHYSIOLOGY, 9. doi:10.3389/fphys.2018.00833
Biomarker predication of efficacy to gemcitabine plus vandetanib in phase II, double blind multicentre randomised controlled trial of gemcitabine placebo in locally advanced or metastatic pancreatic carcinoma
Evans, A., Jackson, R., Shaw, V. E., Ghaneh, P., Wadsley, J., Valle, J. W., . . . Middleton, G. (2018). Biomarker predication of efficacy to gemcitabine plus vandetanib in phase II, double blind multicentre randomised controlled trial of gemcitabine placebo in locally advanced or metastatic pancreatic carcinoma. Pancreatology, 18(4), S127-S128. doi:10.1016/j.pan.2018.05.343
2017
Vandetanib plus gemcitabine versus placebo plus gemcitabine in locally advanced or metastatic pancreatic carcinoma (ViP): a prospective, randomised, double-blind, multicentre phase 2 trial
Middleton, G., Palmer, D. H., Greenhalf, W., Ghaneh, P., Jackson, R., Cox, T., . . . Neoptolemos, J. P. (2017). Vandetanib plus gemcitabine versus placebo plus gemcitabine in locally advanced or metastatic pancreatic carcinoma (ViP): a prospective, randomised, double-blind, multicentre phase 2 trial. The Lancet Oncology, 18(4), 486-499. doi:10.1016/S1470-2045(17)30084-0
2016
Combined analysis of cytidine deaminase mRNA transcript expression with hENT1 protein expression on tissue microarrays from the ESPAC-3 trial helps predict patient survival with gemcitabine treatment
Aughton, K., Elander, N., Palmer, D., Cox, T., Campbell, F., Garner, E., . . . Greenhalf, W. (2016). Combined analysis of cytidine deaminase mRNA transcript expression with hENT1 protein expression on tissue microarrays from the ESPAC-3 trial helps predict patient survival with gemcitabine treatment. Pancreatology, 16(3), S30. doi:10.1016/j.pan.2016.05.104
Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus
Jenkinson, C., Elliott, V., Evans, A., Oldfield, L., Jenkins, R., O'Brien, D., . . . Costello-Goldring, E. (2016). Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus. Clinical Cancer Research, 22(7), 1734-1743. doi:10.1158/1078-0432.ccr-15-0879
2012
The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion
Evans, A., & Costello, E. (2012). The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion. FRONTIERS IN PHYSIOLOGY, 3. doi:10.3389/fphys.2012.00270