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Research

Research grants

Denervation of small numbers of fibres during ageing leads to dysregulation of ROS and functional changes in whole skeletal muscles

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

April 2013 - March 2016

Dietary polyphenols as modulators of redox signalling pathways to reduce chronio inflammation in the elderly

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

April 2011 - January 2015

Centre of Excellence in musculoskeletal ageing research (MRC CIMA)

MEDICAL RESEARCH COUNCIL

June 2012 - December 2017

Translational research into Frailty for the benefit of Older People

THE DOWAGER COUNTESS ELEANOR PEEL TRUST (UK)

February 2009 - April 2012

Molecular mechanisms of preservation of muscle with age by HSP70.

EUROPEAN COMMISSION

August 2002 - July 2004

Extracellular Reactive Oxygen Species as Propagators of Tissue Ageing.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

July 2002 - February 2006

Insulin resistance mediates age-related loss of muscle mass and function

RESEARCH INTO AGEING

February 2007 - February 2010

Pilot Study to investigate the role of glutamine in the early protective stress response.

INTENSIVE CARE SOCIETY (UK)

July 2006 - July 2009

Role of defective mitochondrial function in the loss of skeletal muscle and weakness that occurs in patients with chronic renal failure

MERSEY KIDNEY FIRST (UK)

June 2011 - November 2013

Capacity building award in integrative mammalian biology

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

January 2007 - October 2015

Modulation of aberrant mitochondrial and cytokine production in muscles of patients with CFS by polyphenols

MEDICAL RESEARCH COUNCIL, THE ME ASSOCIATION (UK)

September 2012 - April 2016

Free radical generation by skeletal muscle: signals for adaptation to contractile activity?

WELLCOME TRUST (UK)

February 2001 - February 2004

The role of heat shock proteins in ageing-related loss of muscle function.

RESEARCH INTO AGEING

April 1998 - April 2001

Examination of the effect of antioxidant supplementation on the ability of cells from the elderly to respond to stress.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

August 2001 - July 2002

The role of heat shock proteins in glutamine-induced protection of skeletal muscle during sepsis.

MEDICAL RESEARCH COUNCIL

September 2005 - December 2008

The role of Heat Shock Factor activation in the age related failure of regeneration in skeletal muscles of old mice.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

October 2006 - September 2009

Ageing-Related Skeletal Muscle Weakness: Mechanisms of Prevention by Stress Proteins.

RESEARCH INTO AGEING

October 2001 - September 2006

Are reactive oxygen species a mediator of skeletal muscle damage and weakness in IIM?

THE MYOSITIS ASSOCIATION (TMA) (USA)

January 2015 - December 2020

Motor unit remodelling contributes to the age-related loss of skeletal muscle fibres

MEDICAL RESEARCH COUNCIL

June 2015 - June 2018