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Andrew Sharp

Dr Andrew Sharp
MBBS, MRCOG, PhD, BSc (Hons)

Contact

A.Sharp@liverpool.ac.uk

+44 (0)151 795 9560

Publications

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2024

Diagnosis and management of selective fetal growth restriction in monochorionic twin pregnancies: A cross-sectional international survey.

Prasad, S., Khalil, A., Kirkham, J. J., Sharp, A., Woolfall, K., Mitchell, T. K., . . . FERN Study Team. (2024). Diagnosis and management of selective fetal growth restriction in monochorionic twin pregnancies: A cross-sectional international survey.. BJOG : an international journal of obstetrics and gynaecology, 131(12), 1684-1693. doi:10.1111/1471-0528.17891

DOI
10.1111/1471-0528.17891
Journal article

Neurodevelopmental outcomes at 2 years in children who received sildenafil therapy in utero: The STRIDER randomised controlled trial.

Sharp, A., Cornforth, C., Jackson, R., Harrold, J., Turner, M. A., Kenny, L. C., . . . STRIDER group. (2024). Neurodevelopmental outcomes at 2 years in children who received sildenafil therapy in utero: The STRIDER randomised controlled trial.. BJOG : an international journal of obstetrics and gynaecology, 131(12), 1673-1683. doi:10.1111/1471-0528.17888

DOI
10.1111/1471-0528.17888
Journal article

The efficacy of sildenafil therapy in dismal prognosis early-onset intrauterine growth restriction: the STRIDER RCT

Sharp, A., Cornforth, C., Jackson, R., Harrold, J., Turner, M. A., Kenny, L., . . . Alfirevic, Z. (n.d.). The efficacy of sildenafil therapy in dismal prognosis early-onset intrauterine growth restriction: the STRIDER RCT. Efficacy and Mechanism Evaluation, 1-61. doi:10.3310/wakv3677

DOI
10.3310/wakv3677
Journal article

Study Protocol. The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? A feasibility, cohort study

DOI
10.1101/2024.09.19.24314025
Preprint

Balancing key stakeholder priorities and ethical principles to design a trial comparing intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy: FERN qualitative study.

Mitchell, T. K., Popa, M., Ashcroft, R. E., Prasad, S., Sharp, A., Carnforth, C., . . . Woolfall, K. (2024). Balancing key stakeholder priorities and ethical principles to design a trial comparing intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy: FERN qualitative study.. BMJ open, 14(8), e080488. doi:10.1136/bmjopen-2023-080488

DOI
10.1136/bmjopen-2023-080488
Journal article

FERN: Is it possible to conduct a Randomised controlled trial of Intervention or Expectant Management for Early Onset Selective Fetal Growth Restriction in Monochorionic Twin Pregnancy: protocol for a prospective, mixed methods feasibility study

Sharp, A. (2024). FERN: Is it possible to conduct a Randomised controlled trial of Intervention or Expectant Management for Early Onset Selective Fetal Growth Restriction in Monochorionic Twin Pregnancy: protocol for a prospective, mixed methods feasibility study. BMJ Open.

Journal article

Repeat Placental Growth Factor-Based Testing in Women With Suspected Preterm Preeclampsia: A Stratified Analysis of the PARROT-2 Trial.

Hurrell, A., Webster, L., Sparkes, J., Battersby, C., Brockbank, A., Clark, K., . . . PARROT-2 Trial Group. (2024). Repeat Placental Growth Factor-Based Testing in Women With Suspected Preterm Preeclampsia: A Stratified Analysis of the PARROT-2 Trial.. Hypertension (Dallas, Tex. : 1979), 81(7), 1561-1573. doi:10.1161/hypertensionaha.123.22411

DOI
10.1161/hypertensionaha.123.22411
Journal article

Ethical considerations of a randomised controlled trial of fetal intervention versus expectant management in monochorionic twin pregnancies with early-onset selective fetal growth restriction.

Ashcroft, R., Woolfall, K., Prasad, S., & Khalil, A. (2024). Ethical considerations of a randomised controlled trial of fetal intervention versus expectant management in monochorionic twin pregnancies with early-onset selective fetal growth restriction.. BJOG : an international journal of obstetrics and gynaecology. doi:10.1111/1471-0528.17776

DOI
10.1111/1471-0528.17776
Journal article

Repeat placental growth factor-based testing in women with suspected preterm pre-eclampsia (PARROT-2): a multicentre, parallel-group, superiority, randomised controlled trial.

Hurrell, A., Webster, L., Sparkes, J., Battersby, C., Brockbank, A., Clark, K., . . . PARROT-2 trial group. (2024). Repeat placental growth factor-based testing in women with suspected preterm pre-eclampsia (PARROT-2): a multicentre, parallel-group, superiority, randomised controlled trial.. Lancet (London, England), 403(10427), 619-631. doi:10.1016/s0140-6736(23)02357-7

DOI
10.1016/s0140-6736(23)02357-7
Journal article

2023

Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study (vol 82, E27, 2023)

Liu, S., Sharp, A., Lu, Z., & Ma, Z. F. (2023). Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study (vol 82, E27, 2023). PROCEEDINGS OF THE NUTRITION SOCIETY. doi:10.1017/S0029665123002768

DOI
10.1017/S0029665123002768
Journal article

NOVEL 3D IN VITRO HUMAN PLACENTA-ON-A-CHIP MODEL DERIVED USING HUMAN TROPHOBLAST STEM CELLS DIFFERENTIATED TOWARDS SYNCYTIOTROPHOBLASTS AND EXTRAVILLOUS TROPHOBLASTS TO MIMIC BOTH VILLI AND IMPLANTATION SIDES OF THE PLACENTA

Radziun, K., Sharp, A., Aye, I., Turner, D., Kadioglu, A., & Yang, M. (2023). NOVEL 3D IN VITRO HUMAN PLACENTA-ON-A-CHIP MODEL DERIVED USING HUMAN TROPHOBLAST STEM CELLS DIFFERENTIATED TOWARDS SYNCYTIOTROPHOBLASTS AND EXTRAVILLOUS TROPHOBLASTS TO MIMIC BOTH VILLI AND IMPLANTATION SIDES OF THE PLACENTA. In PLACENTA Vol. 140 (pp. E27-E28). Retrieved from https://www.webofscience.com/

Conference Paper

Pregnancy-Related Complications and Incidence of Atrial Fibrillation: A Systematic Review.

Al Bahhawi, T., Aqeeli, A., Harrison, S. L., Lane, D. A., Skjøth, F., Buchan, I., . . . Lip, G. Y. H. (2023). Pregnancy-Related Complications and Incidence of Atrial Fibrillation: A Systematic Review.. Journal of clinical medicine, 12(4), 1316. doi:10.3390/jcm12041316

DOI
10.3390/jcm12041316
Journal article

2-Year Neurodevelopmental Outcomes in Children Who Received Sildenafil Therapy in Utero: The STRIDER RCT

DOI
10.2139/ssrn.4544766
Preprint

Induction of labour versus expectant management between 36+0 weeks and 40+6 weeks in twins: A systematic review of literature

Oliver, E., Navaratnam, K., & Sharp, A. (2023). Induction of labour versus expectant management between 36+0 weeks and 40+6 weeks in twins: A systematic review of literature. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 130 (pp. 33-34). Retrieved from https://www.webofscience.com/

Conference Paper

Low iodine knowledge in a group of Chinese breastfeeding women with adequate iodine status

Liu, S., Sharp, A., Lu, Z., & Ma, Z. F. (2023). Low iodine knowledge in a group of Chinese breastfeeding women with adequate iodine status. In PROCEEDINGS OF THE NUTRITION SOCIETY Vol. 82. doi:10.1017/S0029665123002975

DOI
10.1017/S0029665123002975
Conference Paper

Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study

Liu, S., Sharp, A., Lu, Z., & Ma, Z. F. (2023). Maternal iodine intake and adherence to iodine supplement recommendations in a group of Chinese women: the results from the WIN cohort study. In PROCEEDINGS OF THE NUTRITION SOCIETY Vol. 82. doi:10.1017/S0029665123000356

DOI
10.1017/S0029665123000356
Conference Paper

Predicting successful vaginal delivery in twin pregnancies

Oliver, E., Navaratnam, K., Bonnett, L., & Sharp, A. (2023). Predicting successful vaginal delivery in twin pregnancies. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 130 (pp. 34). Retrieved from https://www.webofscience.com/

Conference Paper

2022

A nationwide cohort study on the impact of gestational diabetes on future cardiovascular events

Bullough, S., Lip, G. Y. H., Fauchier, G., Herbert, J., Sharp, A., Bisson, A., . . . Fauchier, L. (2022). A nationwide cohort study on the impact of gestational diabetes on future cardiovascular events. In EUROPEAN HEART JOURNAL Vol. 43 (pp. 2599). Retrieved from https://www.webofscience.com/

Conference Paper

Associations between pregnancy complications and incident cardiovascular disease: a nationwide data linkage study in Wales

Al Bahhawi, T., Harrison, S. L., Lane, D. A., Buchan, I., Skjoth, F., Sharp, A., . . . Lip, G. Y. H. (2022). Associations between pregnancy complications and incident cardiovascular disease: a nationwide data linkage study in Wales. In EUROPEAN HEART JOURNAL Vol. 43 (pp. 524). Retrieved from https://www.webofscience.com/

Conference Paper

Role of multiple- and single-pregnancy complications with incident cardiovascular diseases: a nationwide data linkage study in Wales

Al Bahhawi, T., Harrison, S. L., Lane, D. A., Buchan, I., Skjoth, F., Sharp, A., . . . Lip, G. Y. H. (2022). Role of multiple- and single-pregnancy complications with incident cardiovascular diseases: a nationwide data linkage study in Wales. In EUROPEAN HEART JOURNAL Vol. 43 (pp. 2516). Retrieved from https://www.webofscience.com/

Conference Paper

Making decisions about radiological imaging in pregnancy

Wiles, R., Hankinson, B., Benbow, E., & Sharp, A. (2022). Making decisions about radiological imaging in pregnancy. BMJ-BRITISH MEDICAL JOURNAL, 377. doi:10.1136/bmj-2022-070486

DOI
10.1136/bmj-2022-070486
Journal article

2021

Short-term outcomes of phosphodiesterase type 5 inhibitors for fetal growth restriction: a study protocol for a systematic review with individual participant data meta-analysis, aggregate meta-analysis, and trial sequential analysis

Liauw, J., Groom, K., Ganzevoort, W., Gluud, C., McKinlay, C. J. D., Sharp, A., . . . von Dadelszen, P. (2021). Short-term outcomes of phosphodiesterase type 5 inhibitors for fetal growth restriction: a study protocol for a systematic review with individual participant data meta-analysis, aggregate meta-analysis, and trial sequential analysis. Systematic Reviews, 10(1). doi:10.1186/s13643-021-01849-5

DOI
10.1186/s13643-021-01849-5
Journal article

Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study

Goodfellow, L., Verwijs, M. C., Care, A., Sharp, A., Ivandic, J., Poljak, B., . . . van de Wijgert, J. H. H. M. (2021). Vaginal bacterial load in the second trimester is associated with early preterm birth recurrence: a nested case-control study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 128(13), 2061-2072. doi:10.1111/1471-0528.16816

DOI
10.1111/1471-0528.16816
Journal article

Maternal selenium levels and whole genome screen in recurrent spontaneous preterm birth population: a nested case control study

Care, A. G., Gupta, J. K., Goodfellow, L., Zhang, G., Monangi, N., Belling, E., . . . Alfirevic, Z. (2021). Maternal selenium levels and whole genome screen in recurrent spontaneous preterm birth population: a nested case control study. European Journal of Obstetrics & Gynecology and Reproductive Biology. doi:10.1016/j.ejogrb.2021.08.015

DOI
10.1016/j.ejogrb.2021.08.015
Journal article

Pregnancy-related complications and incidence of atrial fibrillation: a systematic review and meta-analysis

Al Bahhawi, T., Aqeeli, A., L Harrison, S., A Lane, D., Buchan, I., Skjoth, F., . . . Lip, G. Y. H. (2021). Pregnancy-related complications and incidence of atrial fibrillation: a systematic review and meta-analysis. EP Europace, 23(Supplement_3). doi:10.1093/europace/euab116.145

DOI
10.1093/europace/euab116.145
Journal article

Vaginal prostaglandin E<sub>2</sub> versus double-balloon catheter for induction of labour for vaginal birth after caesarean section: A retrospective cohort study

Bullough, S., Southward, J., & Sharp, A. (2021). Vaginal prostaglandin E<sub>2</sub> versus double-balloon catheter for induction of labour for vaginal birth after caesarean section: A retrospective cohort study. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 259, 90-94. doi:10.1016/j.ejogrb.2021.02.007

DOI
10.1016/j.ejogrb.2021.02.007
Journal article

Investigation of the outcome of pregnancies complicated by increased fetal movements and their relationship to underlying causes - A prospective cohort study

Sharp, I., Adeyeye, T., Peacock, L., Mahdi, A., Farrant, K., Sharp, A. N., . . . Heazell, A. E. P. (2021). Investigation of the outcome of pregnancies complicated by increased fetal movements and their relationship to underlying causes - A prospective cohort study. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 100(1), 91-100. doi:10.1111/aogs.13961

DOI
10.1111/aogs.13961
Journal article

Pregnancy loss following transabdominal chorionic villus sampling or amniocentesis in twin pregnancies

Khairudin, D., Chilton, R., Navaratnam, K., Alfirevic, Z., & Sharp, A. (2021). Pregnancy loss following transabdominal chorionic villus sampling or amniocentesis in twin pregnancies. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 128 (pp. 46-47). Retrieved from https://www.webofscience.com/

Conference Paper

Socioeconomic determinants of early years respiratory health, and the impact on later life

Busuulwa, P., & Sharp, A. (2021). Socioeconomic determinants of early years respiratory health, and the impact on later life. doi:10.1183/2312508x.10015320

DOI
10.1183/2312508x.10015320
Journal article

2020

The PLANES study: a protocol for a randomised controlled feasibility study of the placental growth factor (PlGF) blood test-informed care versus standard care alone for women with a small for gestational age fetus at or after 32+0weeks' gestation

Gent, J., Bullough, S., Harrold, J., Jackson, R., Woolfall, K., Andronis, L., . . . Sharp, A. (2020). The PLANES study: a protocol for a randomised controlled feasibility study of the placental growth factor (PlGF) blood test-informed care versus standard care alone for women with a small for gestational age fetus at or after 32+0weeks' gestation. PILOT AND FEASIBILITY STUDIES, 6(1). doi:10.1186/s40814-020-00722-x

DOI
10.1186/s40814-020-00722-x
Journal article

Cervical pessary for short cervix in high risk pregnant women: 5 years experience in a single centre.

Ivandic, J., Care, A., Goodfellow, L., Poljak, B., Sharp, A., Roberts, D., & Alfirevic, Z. (2020). Cervical pessary for short cervix in high risk pregnant women: 5 years experience in a single centre.. The Journal of Maternal-Fetal and Neonatal Medicine, 33(8), 1370-1376. doi:10.1080/14767058.2018.1519018

DOI
10.1080/14767058.2018.1519018
Journal article

Effect of sildenafil on maternal hemodynamics in pregnancies complicated by severe early‐onset fetal growth restriction: planned subgroup analysis from a multicenter randomized placebo‐controlled double‐blind trial

Khalil, A., Sharp, A. N., Cornforth, C., Jackson, R., Mousa, H., Stock, S., . . . Alfirevic, Z. (2020). Effect of sildenafil on maternal hemodynamics in pregnancies complicated by severe early‐onset fetal growth restriction: planned subgroup analysis from a multicenter randomized placebo‐controlled double‐blind trial. Ultrasound in Obstetrics and Gynecology, 55(2), 198-209. doi:10.1002/uog.20851

DOI
10.1002/uog.20851
Journal article

2019

OP12.10: Pregnancy loss following chorionic villus sampling or amniocentesis in twin pregnancies: two decades in a UK tertiary fetal medicine centre

Navaratnam, K., Albloushi, D., Alfirevic, Z., & Sharp, A. (2019). OP12.10: Pregnancy loss following chorionic villus sampling or amniocentesis in twin pregnancies: two decades in a UK tertiary fetal medicine centre. Ultrasound in Obstetrics &amp; Gynecology, 54(S1), 126. doi:10.1002/uog.20772

DOI
10.1002/uog.20772
Journal article

Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial

Duhig, K., Myers, J., Seed, P. T., Sparkes, J., Lowe, J., Hunter, R. M., . . . Chappell, L. C. (2019). Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial. Lancet, 393(10183), 1807-1818. doi:10.1016/S0140-6736(18)33212-4

DOI
10.1016/S0140-6736(18)33212-4
Journal article

Mortality in the UK STRIDER trial of sildenafil therapy for the treatment of severe early-onset fetal growth restriction

Sharp, A., Cornforth, C., Jackson, R., Harrold, J., Turner, M. A., Kenny, L., . . . Alfirevic, Z. (2019). Mortality in the UK STRIDER trial of sildenafil therapy for the treatment of severe early-onset fetal growth restriction. LANCET CHILD & ADOLESCENT HEALTH, 3(3), E2-E3. doi:10.1016/S2352-4642(19)30020-3

DOI
10.1016/S2352-4642(19)30020-3
Journal article

Comparison of the Cook cervical ripening balloon and prostaglandin E2 gel for induction of labour in women who have had a previous caesarean section

Southward, J., Sharp, A., Weeks, A., & Barton, A. (2019). Comparison of the Cook cervical ripening balloon and prostaglandin E2 gel for induction of labour in women who have had a previous caesarean section. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 126 (pp. 95). Retrieved from https://www.webofscience.com/

Conference Paper

Repeated placental growth factor measurements in the assessment of women with suspected pre-eclampsia

Duhig, K., Myers, J., Sharp, A., Seed, P., Shennan, A., Chappell, L., & Webster, L. (2019). Repeated placental growth factor measurements in the assessment of women with suspected pre-eclampsia. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 126 (pp. E137-E138). Retrieved from https://www.webofscience.com/

Conference Paper

Suspected pre-eclampsia: the assessment of women with repeated placental growth factor measurements

Duhig, K., Webster, L., Myers, J., Sharp, A., Seed, P., Shennan, A., & Chappell, L. (2019). Suspected pre-eclampsia: the assessment of women with repeated placental growth factor measurements. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 126 (pp. 167). Retrieved from https://www.webofscience.com/

Conference Paper

The assessment of women with suspected preeclampsia with repeated placental growth factor measurements

Duhig, K., Webster, L., Myers, J., Sharp, A., Seed, P., Shennan, A., & Chappell, L. (2019). The assessment of women with suspected preeclampsia with repeated placental growth factor measurements. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 126 (pp. 37-38). Retrieved from https://www.webofscience.com/

Conference Paper

Use of a fetal pillow in caesarean section at full dilatation - a comparative study of maternal and fetal outcomes

Sacre, H., & Sharp, A. (2019). Use of a fetal pillow in caesarean section at full dilatation - a comparative study of maternal and fetal outcomes. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 126 (pp. 93). Retrieved from https://www.webofscience.com/

Conference Paper

2018

138. Placental growth factor to assess and diagnose hypertensive pregnant women: A stepped wedge randomised controlled trial (PARROT)

Duhig, K., Lowe, J., Fetherston, J., Bahl, R., Bambridge, G., Barnfield, S., . . . Chappell, L. (2018). 138. Placental growth factor to assess and diagnose hypertensive pregnant women: A stepped wedge randomised controlled trial (PARROT). Pregnancy Hypertension, 13, S26. doi:10.1016/j.preghy.2018.08.079

DOI
10.1016/j.preghy.2018.08.079
Journal article

81. Maternal cardiovascular changes secondary to sildenafil intake in pregnancies complicated by severe fetal growth restriction: STRIDER trial

Khalil, A., Sharp, A., Cornforth, C., Jackson, R., Mousa, H., Stock, S., . . . Alfirevic, Z. (2018). 81. Maternal cardiovascular changes secondary to sildenafil intake in pregnancies complicated by severe fetal growth restriction: STRIDER trial. Pregnancy Hypertension, 13, S70. doi:10.1016/j.preghy.2018.08.207

DOI
10.1016/j.preghy.2018.08.207
Journal article

OP19.10: Maternal cardiovascular changes secondary to sildenafil intake in pregnancies complicated by severe fetal growth restriction: STRIDER trial

Khalil, A., Sharp, A., Cornforth, C., Jackson, R., Mousa, H., Stock, S., . . . Alfirevic, Z. (2018). OP19.10: Maternal cardiovascular changes secondary to sildenafil intake in pregnancies complicated by severe fetal growth restriction: STRIDER trial. Ultrasound in Obstetrics &amp; Gynecology, 52(S1), 125. doi:10.1002/uog.19574

DOI
10.1002/uog.19574
Journal article

Placental Growth Factor informed management of suspected pre-eclampsia or fetal growth restriction: The MAPPLE cohort study

Sharp, A., Chappell, L. C., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., . . . Alfirevic, Z. (2018). Placental Growth Factor informed management of suspected pre-eclampsia or fetal growth restriction: The MAPPLE cohort study. PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH, 14, 228-233. doi:10.1016/j.preghy.2018.03.013

DOI
10.1016/j.preghy.2018.03.013
Journal article

Maternal sildenafil for severe fetal growth restriction (STRIDER): a multicentre, randomised, placebo-controlled, double-blind trial

Sharp, A., Cornforth, C., Turner, M. A., Harrold, J., Kenny, L. C., Jackson, R., . . . Alfirevic, Z. (2018). Maternal sildenafil for severe fetal growth restriction (STRIDER): a multicentre, randomised, placebo-controlled, double-blind trial. Lancet Child and Adolescent Health, 2(2), 93-102. doi:10.1016/S2352-4642(17)30173-6

DOI
10.1016/S2352-4642(17)30173-6
Journal article

Maternal cardiovascular changes secondary to sildenafil intake in pregnancies complicated by severe fetal growth restriction: STRIDER trial

Khalil, A., Sharp, A., Cornforth, C., Jackson, R., Mousa, H., Stock, S., . . . Alfirevic, Z. (2018). Maternal cardiovascular changes secondary to sildenafil intake in pregnancies complicated by severe fetal growth restriction: STRIDER trial. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 125 (pp. 25). Retrieved from https://www.webofscience.com/

Conference Paper

2017

STRIDER (Sildenafil TheRapy in dismal prognosis early onset fetal growth restriction): an international consortium of randomised placebo-controlled trials

Pels, A., Kenny, L. C., Alfirevic, Z., Baker, P. N., von Dadelszen, P., Gluud, C., . . . Groom, K. M. (2017). STRIDER (Sildenafil TheRapy in dismal prognosis early onset fetal growth restriction): an international consortium of randomised placebo-controlled trials. BMC PREGNANCY AND CHILDBIRTH, 17. doi:10.1186/s12884-017-1594-z

DOI
10.1186/s12884-017-1594-z
Journal article

OC01.05: STRIDER UK: a randomised controlled trial of sildenafil therapy in dismal prognosis early‐onset intrauterine growth restriction

Sharp, A., Comforth, C., Jackson, R., Turner, M., Kenny, L., Baker, P., . . . Alfirevic, Z. (2017). OC01.05: STRIDER UK: a randomised controlled trial of sildenafil therapy in dismal prognosis early‐onset intrauterine growth restriction. Ultrasound in Obstetrics &amp; Gynecology, 50(S1), 3. doi:10.1002/uog.17574

DOI
10.1002/uog.17574
Journal article

OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction – The MAPPLE cohort study

Sharp, A., Chappell, L., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., . . . Alfirevic, Z. (2017). OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction – The MAPPLE cohort study. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 9, 9-10. doi:10.1016/j.preghy.2017.07.025

DOI
10.1016/j.preghy.2017.07.025
Journal article

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Shakur, H., Roberts, I., Fawole, B., Chaudhri, R., El-Sheikh, M., Akintan, A., . . . Coordinators, N. (2017). Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. The Lancet, 389(10084), 2105-2116. doi:10.1016/S0140-6736(17)30638-4

DOI
10.1016/S0140-6736(17)30638-4
Journal article

Audit of the use of revealed PLGF for the management of hypertension in pregnancy

Smith, K., Sharp, A., Agarwal, U., & Alfirevic, Z. (2017). Audit of the use of revealed PLGF for the management of hypertension in pregnancy. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/

Poster

Two year outcome of pregnancies complicated by low PAPP-A (< 0.3 MoM) at a tertiary fetal medicine unit

Sharp, A., Denton-Cardew, L., Agarwal, U., & Alfirevic, Z. (2017). Two year outcome of pregnancies complicated by low PAPP-A (< 0.3 MoM) at a tertiary fetal medicine unit. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/

Poster

2016

Fetal tumors

Sharp, A., & Alfirevic, Z. (2016). Fetal tumors. In Fetal Medicine (pp. 192-200). Cambridge University Press. doi:10.1017/cbo9781107585843.014

DOI
10.1017/cbo9781107585843.014
Chapter

Short versus Standard Mifepristone and Misoprostol Regimen for Second- and Third-Trimester Termination of Pregnancy for Fetal Anomaly

Sharp, A., Navaratnam, K., Abreu, P., & Alfirevic, Z. (2016). Short versus Standard Mifepristone and Misoprostol Regimen for Second- and Third-Trimester Termination of Pregnancy for Fetal Anomaly. Fetal Diagnosis and Therapy: clinical advances and basic research, 39(2), 140-146. doi:10.1159/000436963

DOI
10.1159/000436963
Journal article

Cervical length at 15<SUP>+0</SUP>-16<SUP>+6</SUP> weeks of gestation in women at high risk of preterm birth

Goodfellow, L., Care, A., Sharp, A., & Alfirevic, Z. (2016). Cervical length at 15<SUP>+0</SUP>-16<SUP>+6</SUP> weeks of gestation in women at high risk of preterm birth. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/

Poster

NEONATAL CARDIOVASCULAR AND CEREBRAL FUNCTION AFTER ANTENATAL MATERNAL EXPOSURE TO MAGNESIUM SULFATE

Kotidis, C., Sharp, A., Alfirevic, Z., Weindling, M., & Turner, M. (2016). NEONATAL CARDIOVASCULAR AND CEREBRAL FUNCTION AFTER ANTENATAL MATERNAL EXPOSURE TO MAGNESIUM SULFATE. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/

Poster

2015

Vasodilators for treating intrauterine growth restriction

Sharp, A. N., & Alfirevic, Z. (n.d.). Vasodilators for treating intrauterine growth restriction. doi:10.1002/14651858.cd011978

DOI
10.1002/14651858.cd011978
Journal article

Short versus standard mifepristone and misoprostol regimen for second and third trimester termination of pregnancy for fetal anomaly

Sharp, A., Navaratnam, K., Abreu, P., & Alfirevic, Z. (2015). Short versus standard mifepristone and misoprostol regimen for second and third trimester termination of pregnancy for fetal anomaly. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 122 (pp. 58). Retrieved from https://www.webofscience.com/

Conference Paper

PlGF bedside testing in routine clinical care: 12 months' experience from a large teaching hospital

Sharp, A., Agarwal, U., & Alfirevic, Z. (2015). PlGF bedside testing in routine clinical care: 12 months' experience from a large teaching hospital. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 122, 46. Retrieved from https://www.webofscience.com/

Journal article

2014

First trimester screening can predict adverse pregnancy outcomes

Sharp, A. N., & Alfirevic, Z. (2014). First trimester screening can predict adverse pregnancy outcomes. PRENATAL DIAGNOSIS, 34(7), 660-667. doi:10.1002/pd.4406

DOI
10.1002/pd.4406
Journal article

PFM.36 Arabin Pessary to Prevent Spontaneous Preterm Birth: Experience of a Specialist Preterm Labour Clinic

Care, A., Sharp, A., & Alfirevic, Z. (2014). PFM.36 Arabin Pessary to Prevent Spontaneous Preterm Birth: Experience of a Specialist Preterm Labour Clinic. Archives of Disease in Childhood - Fetal and Neonatal Edition, 99(Suppl 1), A93.2-A93. doi:10.1136/archdischild-2014-306576.266

DOI
10.1136/archdischild-2014-306576.266
Journal article

PFM.38 Clinical Outcomes from a Specialist Preterm Labour Clinic: A 5 Year Overview

Care, A., Perry, C., Roberts, D., Sharp, A., & Alfirevic, Z. (2014). PFM.38 Clinical Outcomes from a Specialist Preterm Labour Clinic: A 5 Year Overview. Archives of Disease in Childhood - Fetal and Neonatal Edition, 99(Suppl 1), A94.1-A94. doi:10.1136/archdischild-2014-306576.268

DOI
10.1136/archdischild-2014-306576.268
Journal article

Provision and practice of specialist preterm labour clinics: a UK survey of practice

Sharp, A. N., & Alfirevic, Z. (2014). Provision and practice of specialist preterm labour clinics: a UK survey of practice. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 121(4), 417-421. doi:10.1111/1471-0528.12512

DOI
10.1111/1471-0528.12512
Journal article

Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast

Sharp, A. N., Heazell, A. E., Baczyk, D., Dunk, C. E., Lacey, H. A., Jones, C. J., . . . Crocker, I. P. (2014). Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast. PLoS ONE, 9(1). doi:10.1371/journal.pone.0087621

DOI
10.1371/journal.pone.0087621
Journal article

Predicting Preterm Birth in Women With Previous Preterm Birth and Cervical Length of ≥25 mm

Care, A. G., Sharp, A. N., Lane, S., Roberts, D., Watkins, L., & Alfirevic, Z. (2014). Predicting Preterm Birth in Women With Previous Preterm Birth and Cervical Length of ≥25 mm. Obstetrical &amp; Gynecological Survey, 69(9), 527-529. doi:10.1097/01.ogx.0000455019.85064.6b

DOI
10.1097/01.ogx.0000455019.85064.6b
Journal article

Predicting preterm birth in women with previous preterm birth and cervical length ≥ 25 mm

Care, A. G., Sharp, A. N., Lane, S., Roberts, D., Watkins, L., & Alfirevic, Z. (2014). Predicting preterm birth in women with previous preterm birth and cervical length ≥ 25 mm. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 43(6), 681-686. doi:10.1002/uog.13241

DOI
10.1002/uog.13241
Journal article

Preterm labour prevention clinics Reply

Sharp, A. N., & Alfirevic, Z. (2014). Preterm labour prevention clinics Reply. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 121(10), 1318. doi:10.1111/1471-0528.12732

DOI
10.1111/1471-0528.12732
Journal article

2013

Vaginal Progesterone, Cerclage or Cervical Pessary for Preventing Preterm Birth in Asymptomatic Singleton Pregnant Women With a History of Preterm Birth and a Sonographic Short Cervix EDITORIAL COMMENT

Alirevic, Z., Owen, J., Carreras Moratonas, E., Sharp, A. N., Szychowski, J. M., & Goya, M. (2013). Vaginal Progesterone, Cerclage or Cervical Pessary for Preventing Preterm Birth in Asymptomatic Singleton Pregnant Women With a History of Preterm Birth and a Sonographic Short Cervix EDITORIAL COMMENT. OBSTETRICAL & GYNECOLOGICAL SURVEY, 68(6), 425-427. doi:10.1097/01.ogx.0000431315.30327.08

DOI
10.1097/01.ogx.0000431315.30327.08
Journal article

Vaginal progesterone, cerclage or cervical pessary for preventing preterm birth in asymptomatic singleton pregnant women with a history of preterm birth and a sonographic short cervix

Alfirevic, Z., Owen, J., Carreras Moratonas, E., Sharp, A. N., Szychowski, J. M., & Goya, M. (2013). Vaginal progesterone, cerclage or cervical pessary for preventing preterm birth in asymptomatic singleton pregnant women with a history of preterm birth and a sonographic short cervix. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 41(2), 146-151. doi:10.1002/uog.12300

DOI
10.1002/uog.12300
Journal article

2012

Can customised sfh charts predict SGA in unexplained stillbirth?

Ingram, E., Sharp, A., & Roberts, D. (2012). Can customised sfh charts predict SGA in unexplained stillbirth?. Archives of Disease in Childhood - Fetal and Neonatal Edition, 97(Suppl 1), A13.2-A13. doi:10.1136/fetalneonatal-2012-301809.39

DOI
10.1136/fetalneonatal-2012-301809.39
Journal article

The relationship between stillbirth, SGA and placental histopathology

Muid, T., Sharp, A., & Roberts, D. (2012). The relationship between stillbirth, SGA and placental histopathology. Archives of Disease in Childhood - Fetal and Neonatal Edition, 97(Suppl 1), A12.3-A13. doi:10.1136/fetalneonatal-2012-301809.37

DOI
10.1136/fetalneonatal-2012-301809.37
Journal article

2011

Inhibition of p53 protects placental trophoblast from hydrogen-peroxide induced apoptosis

Sharp, A. N., Crocker, I. P., Baker, P. N., & Heazell, A. E. P. (2011). Inhibition of p53 protects placental trophoblast from hydrogen-peroxide induced apoptosis. Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Supplement 1), Fa4. doi:10.1136/adc.2011.300160.12

DOI
10.1136/adc.2011.300160.12
Journal article

Intra-uterine growth restriction is associated with increased apoptosis and altered expression of proteins in the p53 pathway in villous trophoblast

Heazell, A. E. P., Sharp, A. N., Baker, P. N., & Crocker, I. P. (2011). Intra-uterine growth restriction is associated with increased apoptosis and altered expression of proteins in the p53 pathway in villous trophoblast. APOPTOSIS, 16(2), 135-144. doi:10.1007/s10495-010-0551-3

DOI
10.1007/s10495-010-0551-3
Journal article

Placental Viral Infection Sensitizes to Endotoxin-Induced Pre-Term Labor: A Double Hit Hypothesis

Cardenas, I., Mor, G., Aldo, P., Lang, S. M., Stabach, P., Sharp, A., . . . Means, R. E. (2011). Placental Viral Infection Sensitizes to Endotoxin-Induced Pre-Term Labor: A Double Hit Hypothesis. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 65(2), 110-117. doi:10.1111/j.1600-0897.2010.00908.x

DOI
10.1111/j.1600-0897.2010.00908.x
Journal article

Modulation of p53 in the human and mouse placenta

Sharp, A., Heazell, A., Baker, P., & Crocker, I. (2011). Modulation of p53 in the human and mouse placenta. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 118(8), 1015. Retrieved from https://www.webofscience.com/

Journal article

The Role of p53 Modulation in Correcting Abberant Placental Apoptosis in Pre-eclampsia and IUGR

Sharp, A. N. (2011). The Role of p53 Modulation in Correcting Abberant Placental Apoptosis in Pre-eclampsia and IUGR. (PhD Thesis, University of Manchester, UK).

Thesis / Dissertation

2010

Placental Apoptosis in Health and Disease

Sharp, A. N., Heazell, A. E. P., Crocker, I. P., & Mor, G. (2010). Placental Apoptosis in Health and Disease. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 64(3), 159-169. doi:10.1111/j.1600-0897.2010.00837.x

DOI
10.1111/j.1600-0897.2010.00837.x
Journal article

Modulation of p53 activity in the pregnant mouse

Sharp, A., Cardenas, I., Heazell, A., Baker, P., Crocker, I., & Mor, G. (2010). Modulation of p53 activity in the pregnant mouse. Archives of Disease in Childhood - Fetal and Neonatal Edition, 95(Supplement 1), Fa36. doi:10.1136/adc.2010.189753.11

DOI
10.1136/adc.2010.189753.11
Journal article

INDUCTION OF P53 PROMOTES APOPTOSIS IN THE VILLOUS TROPHOBLAST

Sharp, A. N., Heazell, A. E. P., Baker, P. N., & Crocker, I. P. (2010). INDUCTION OF P53 PROMOTES APOPTOSIS IN THE VILLOUS TROPHOBLAST. In PLACENTA Vol. 31 (pp. A131). Retrieved from https://www.webofscience.com/

Conference Paper

The Effect of p53 Modulation on Extravillous and Villous Trophoblast Apoptosis.

Sharp, A. N., Heazell, A. E., Crocker, I. P., Baker, P. N., & Mor, G. (2010). The Effect of p53 Modulation on Extravillous and Villous Trophoblast Apoptosis.. In REPRODUCTIVE SCIENCES Vol. 17 (pp. 332A). Retrieved from https://www.webofscience.com/

Conference Paper

The Effect of p53 Modulation on Pregnancy Outcome in Mice

Sharp, A. N., Heazell, A. E., Cardenas, I., Crocker, I. P., Baker, P. N., & Mor, G. (2010). The Effect of p53 Modulation on Pregnancy Outcome in Mice. In REPRODUCTIVE SCIENCES Vol. 17 (pp. 331A). Retrieved from https://www.webofscience.com/

Conference Paper

2009

The Modulation of Trophoblast Apoptosis through p53 Manipulations.

Sharp, A. N., Heazell, A. E., Baker, P. N., & Crocker, I. P. (2009). The Modulation of Trophoblast Apoptosis through p53 Manipulations.. REPRODUCTIVE SCIENCES, 16(3), 351A. Retrieved from https://www.webofscience.com/

Journal article

The modulation of p53-induced apoptosis in BeWo cells and cultured primary trophoblast cells

Sharp, A., Heazell, A., Baker, P., & Crocker, I. (2009). The modulation of p53-induced apoptosis in BeWo cells and cultured primary trophoblast cells. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 116(10), 1412. Retrieved from https://www.webofscience.com/

Journal article

2008

Apoptosis in BeWo cells is p53 dependent and amenable to modulation

Sharp, A. N., Heazell, A. E., Baker, P. N., & Crocker, I. P. (2008). Apoptosis in BeWo cells is p53 dependent and amenable to modulation. In PLACENTA Vol. 29 (pp. A97). Retrieved from https://www.webofscience.com/

Conference Paper

2004

2001

Solid-phase amplification for detection of C282y and H63D hemochromatosis (HFE) gene mutations.

Turner, M. S., Penning, S., Sharp, A., Hyland, V. J., Harris, R., Morris, C. P., & van Daal, A. (2001). Solid-phase amplification for detection of C282y and H63D hemochromatosis (HFE) gene mutations.. Clinical chemistry, 47(8), 1384-1389.

Journal article

Undated

2-Year Neurodevelopmental Outcomes in Children Who Received Sildenafil Therapy in Utero: The STRIDER RCT

Preprint