Publications
Selected publications
- Human Papillomavirus Testing in Head and Neck Squamous Cell Carcinoma: Best Practice for Diagnosis (Chapter - 2014)
- Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma (Journal article - 2013)
- Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma (Journal article - 2010)
2024
TNM 8 staging system beyond p16: Double HPV/p16 status is superior to p16 alone in predicting outcome in oropharyngeal squamous cell carcinoma.
von Buchwald, C., Jakobsen, K. K., Carlander, A. -L. F., Tous, S., Grønhøj, C., Rasmussen, J. H., . . . HNCIG-EPIC group. (2024). TNM 8 staging system beyond p16: Double HPV/p16 status is superior to p16 alone in predicting outcome in oropharyngeal squamous cell carcinoma.. European journal of cancer (Oxford, England : 1990), 211, 114329. doi:10.1016/j.ejca.2024.114329
Socioeconomic Deprivation Correlates With Incomplete Radiotherapy Treatment in Head and Neck Cancer.
Brooker, R., Parvulescu, P., Jones, L., Meysner, S., Moore, D., Dailey, Y., . . . Jones, T. (2024). Socioeconomic Deprivation Correlates With Incomplete Radiotherapy Treatment in Head and Neck Cancer.. Clinical oncology (Royal College of Radiologists (Great Britain)), 37, 103649. doi:10.1016/j.clon.2024.10.001
A protocol for the longitudinal investigation of cancer related fatigue in head and neck cancer with an emphasis on the role of physical activity.
Narasimhan, P., Levy, A. R., Rogers, S. N., Schache, A. G., Patterson, J. M., Williams, N. H., . . . Midgley, A. W. (2024). A protocol for the longitudinal investigation of cancer related fatigue in head and neck cancer with an emphasis on the role of physical activity.. PloS one, 19(8), e0308400. doi:10.1371/journal.pone.0308400
The prognostic value of pre-treatment sarcopenia in overall survival in head and neck cancer patients: a systematic review.
Syziu, A., & Schache, A. (2024). The prognostic value of pre-treatment sarcopenia in overall survival in head and neck cancer patients: a systematic review.. International journal of oral and maxillofacial surgery, S0901-5027(24)00221-2. doi:10.1016/j.ijom.2024.07.008
Developing and Validating a Multivariable Prognostic-Predictive Classifier for Treatment Escalation of Oropharyngeal Squamous Cell Carcinoma: The PREDICTR-OPC Study.
Mehanna, H., Rapozo, D., von Zeidler, S. V., Harrington, K. J., Winter, S. C., Hartley, A., . . . Robinson, M. (2024). Developing and Validating a Multivariable Prognostic-Predictive Classifier for Treatment Escalation of Oropharyngeal Squamous Cell Carcinoma: The PREDICTR-OPC Study.. Clinical cancer research : an official journal of the American Association for Cancer Research, 30(2), 356-367. doi:10.1158/1078-0432.ccr-23-1013
Figure 2 from Developing and Validating a Multivariable Prognostic-Predictive Classifier for Treatment Escalation of Oropharyngeal Squamous Cell Carcinoma: The PREDICTR-OPC Study
Mehanna, H., Rapozo, D., von Zeidler, S. V., Harrington, K. J., Winter, S. C., Hartley, A., . . . Robinson, M. (2024). Figure 2 from Developing and Validating a Multivariable Prognostic-Predictive Classifier for Treatment Escalation of Oropharyngeal Squamous Cell Carcinoma: The PREDICTR-OPC Study. doi:10.1158/1078-0432.25011386.v1
2023
Percutaneous tracheostomy in the surgical management of oral malignancy: an emerging standard of care.
Sato, T., Alimadadian, M., Schache, A., & Shaw, R. (2023). Percutaneous tracheostomy in the surgical management of oral malignancy: an emerging standard of care.. The British journal of oral & maxillofacial surgery, 61(10), 696-703. doi:10.1016/j.bjoms.2023.10.006
Health-related quality of life, functional outcomes, and complications after sentinel lymph node biopsy and elective neck dissection in early oral cancer: A systematic review
Mcdonald, C., Kent, S., Schache, A., Rogers, S., & Shaw, R. (2023). Health-related quality of life, functional outcomes, and complications after sentinel lymph node biopsy and elective neck dissection in early oral cancer: A systematic review. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK. doi:10.1002/hed.27495
Determining the Effectiveness of Fibrin Sealants in Reducing Complications in Patients Undergoing Lateral Neck Dissection (DEFeND): A Randomised External Pilot Trial.
Bajwa, M. S., Jackson, R., Dhanda, J., Tudur Smith, C., Shaw, R. J., & Schache, A. G. (2023). Determining the Effectiveness of Fibrin Sealants in Reducing Complications in Patients Undergoing Lateral Neck Dissection (DEFeND): A Randomised External Pilot Trial.. Cancers, 15(20), 5073. doi:10.3390/cancers15205073
ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): Protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer
Midgley, A., Levy, A., Rogers, S., Brooker, R., Bryant, V., Cherry, M., . . . Patterson, J. (2023). ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): Protocol for a feasibility study investigating a patient-centred approach to exercise for people with head and neck cancer. PLoS One.
Head and neck reconstruction in the SARS-CoV-2 pandemic era: outcomes and lessons learned
Ho, M., Hazari, A., Schache, A., Nugent, M., Tighe, D., Smith, A., . . . Shaw, R. (n.d.). Head and neck reconstruction in the SARS-CoV-2 pandemic era: outcomes and lessons learned. Frontiers of Oral and Maxillofacial Medicine, 5, 15. doi:10.21037/fomm-21-4
Lessons learned from the multidisciplinary UK National Flap Registry initiative and plans for the future
Ho, M., Schache, A., Nugent, M., & Hazari, A. (n.d.). Lessons learned from the multidisciplinary UK National Flap Registry initiative and plans for the future. Frontiers of Oral and Maxillofacial Medicine, 5, 16. doi:10.21037/fomm-21-2
Head and neck reconstruction in the vessel depleted neck using robot-assisted harvesting of the internal mammary vessels
Kerai, A., Modi, P., Shackcloth, M., Schache, A. G., & Shaw, R. J. (2023). Head and neck reconstruction in the vessel depleted neck using robot-assisted harvesting of the internal mammary vessels. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 61(5), 368-372. doi:10.1016/j.bjoms.2023.04.004
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis.
Mehanna, H., Taberna, M., von Buchwald, C., Tous, S., Brooks, J., Mena, M., . . . HNCIG-EPIC group. (2023). Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis.. The Lancet. Oncology, 24(3), 239-251. doi:10.1016/s1470-2045(23)00013-x
Academic Training in Oral & Maxillofacial Surgery - when and how to enter the pathway.
Payne, K. F. B., Higginson, J., Basyuni, S., Goodson, A. M. C., Chadha, A., Elledge, R., . . . Schache, A. (2023). Academic Training in Oral & Maxillofacial Surgery - when and how to enter the pathway.. The British journal of oral & maxillofacial surgery, S0266-4356(23)00038-4. doi:10.1016/j.bjoms.2023.01.003
Accuracy of preoperative clinical examination and imaging for mandibular resection in oral cancer: a systematic review of diagnostic test accuracy studies
Brown, J. S., Crowder, L. P., Willcocks, E. J., Bajwa, M. S., & Schache, A. G. (2023). Accuracy of preoperative clinical examination and imaging for mandibular resection in oral cancer: a systematic review of diagnostic test accuracy studies. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 61(1), 28-38. doi:10.1016/j.bjoms.2022.10.005
2022
Value of p53 sequencing in the prognostication of head and neck cancer: a systematic review and meta-analysis
Basyuni, S., Nugent, G., Ferro, A., Barker, E., Reddin, I., Jones, O., . . . Schache, A. (2022). Value of p53 sequencing in the prognostication of head and neck cancer: a systematic review and meta-analysis. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-25291-2
Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors
Gormley, M., Creaney, G., Schache, A., Ingarfield, K., & Conway, D. I. (2022). Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors. BRITISH DENTAL JOURNAL, 233(9), 780-786. doi:10.1038/s41415-022-5166-x
Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries
Glasbey, J. C., Abbott, T. E. F., Ademuyiwa, A., Adisa, A., AlAmeer, E., Alshryda, S., . . . Bhangu, A. (2022). Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries. LANCET, 400(10363), 1607-1617. doi:10.1016/S0140-6736(22)01846-3
Oral cavity cancer
O'Connell, P. R., McCaskie, A. W., & Sayers, R. D. (2022). Oral cavity cancer. In Bailey & Love's Short Practice of Surgery (pp. 813-830). CRC Press. doi:10.1201/9781003106852-60
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs
Eschweiler, S., Ramirez-Suastegui, C., Li, Y., King, E., Chudley, L., Thomas, J., . . . Ottensmeier, C. H. (2022). Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs. NATURE, 605(7911), 741-+. doi:10.1038/s41586-022-04685-2
Immediate postoperative care on high dependency unit or ward following microvascular free tissue transfer: lessons learnt from a change in practice imposed during the COVID-19 pandemic
James, P., Bekiroglu, F., Broderick, D., Khattak, O., Lowe, D., Schache, A., . . . Rogers, S. N. (2022). Immediate postoperative care on high dependency unit or ward following microvascular free tissue transfer: lessons learnt from a change in practice imposed during the COVID-19 pandemic. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 60(3), 343-349. doi:10.1016/j.bjoms.2021.08.002
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
Adamina, M., Ademuyiwa, A., Adisa, A., Bhangu, A. A., Bravo, A. M., Cunha, M. F., . . . Rodrigo, V. S. D. (2022). The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study. COLORECTAL DISEASE, 24(6), 708-726. doi:10.1111/codi.16117
SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
COVIDSurg Collaborative., & GlobalSurg Collaborative. (2022). SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.. Anaesthesia, 77(1), 28-39. doi:10.1111/anae.15563
2021
Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic
McLean, K. A., Kamarajah, S. K., Chaudhry, D., Gujjuri, R. R., Raubenheimer, K., Trout, I., . . . Wischhusen, S. (2021). Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic. BRITISH JOURNAL OF SURGERY, 108(12), 1448-1464. doi:10.1093/bjs/znab336
Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
Khatri, C., Ward, A. E., Nepogodiev, D., Ahmed, I., Chaudhry, D., Dhaif, F., . . . Smart, N. J. (2021). Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study. BMJ OPEN, 11(11). doi:10.1136/bmjopen-2021-050830
Y Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score
Bravo, L., Nepogodiev, D., Glasbey, J. C., Li, E., Simoes, J. F. F., Kamarajah, S. K., . . . Mazingi, D. (2021). Y Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score. BRITISH JOURNAL OF SURGERY, 108(11), 1274-1292. doi:10.1093/bjs/znab183
Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
Schache, A. G., Shaw, R., Ho, M. W. S., Winter, S. C., Glasbey, J., Ganly, I., . . . SICO, I. S. S. O. (2021). Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery. BJS OPEN, 5(6). doi:10.1093/bjsopen/zrab112
Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study
Glasbey, J. C., Ademuyiwa, A., Adisa, A., AlAmeer, E., Arnaud, A. P., Ayasra, F., . . . Aldawbali, M. (2021). Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study. LANCET ONCOLOGY, 22(11), 1507-1517. doi:10.1016/S1470-2045(21)00493-9
Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study
Simoes, J. F. F., Nepogodiev, D., Ademuyiwa, A., Buarque, I., El-Boghdadly, K., Gebreyohanes, M., . . . Vazquez Melero, A. (2021). Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. ANAESTHESIA, 76(11), 1454-1464. doi:10.1111/anae.15560
Outcomes of microvascular composite reconstruction for mandibular osteoradionecrosis
O'Connell, J. E., Brown, J. S., Rogers, S. N., Bekiroglu, F., Schache, A., & Shaw, R. J. (2021). Outcomes of microvascular composite reconstruction for mandibular osteoradionecrosis. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 59(9), 1031-1035. doi:10.1016/j.bjoms.2020.11.013
Adjuvant management of locally advanced oral squamous cell carcinoma – real world challenges and opportunities
Brooker, R. C., Hobkirk, A., Cashman, H., Sato, T., Broderick, D., Wong, H., . . . Schache, A. G. (n.d.). Adjuvant management of locally advanced oral squamous cell carcinoma – real world challenges and opportunities. British Journal of Oral and Maxillofacial Surgery. doi:10.1016/j.bjoms.2020.08.034
NICO Phase II clinical trial - focus on an emerging immunotherapy strategy for the adjuvant treatment of locally-advanced oral cancers
Brooker, R. C., Schache, A. G., & Sacco, J. J. (2021). NICO Phase II clinical trial - focus on an emerging immunotherapy strategy for the adjuvant treatment of locally-advanced oral cancers. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 59(8), 959-962. doi:10.1016/j.bjoms.2020.08.059
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
Schache, A. (2021). SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. British Journal of Surgery, 108(9), 1056-1063. doi:10.1093/bjs/znab101
Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: main results of a cluster preference randomised controlled trial
Rogers, S. N., Allmark, C., Bekiroglu, F., Edwards, R. T., Fabbroni, G., Flavel, R., . . . Kanatas, A. (2021). Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: main results of a cluster preference randomised controlled trial. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 278(9), 3435-3449. doi:10.1007/s00405-020-06533-3
Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study
Akowuah, E., Benson, R. A., Caruana, E. J., Chetty, G., Edwards, J., Forlani, S., . . . Vaja, R. (2021). Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 162(2), E355-E372. doi:10.1016/j.jtcvs.2021.03.091
UK Head and neck cancer surgical capacity during the second wave of the COVID-19 pandemic: Have we learned the lessons? COVIDSurg collaborative
Shaw, R. (2021). UK Head and neck cancer surgical capacity during the second wave of the COVID-19 pandemic: Have we learned the lessons? COVIDSurg collaborative. CLINICAL OTOLARYNGOLOGY, 46(4), 729-735. doi:10.1111/coa.13749
Virtual surgical planning in mandibular reconstruction using scapular free flaps: a technical note
O'Connell, J. E., Schache, A. G., Fleming, S., & Shaw, R. J. (2021). Virtual surgical planning in mandibular reconstruction using scapular free flaps: a technical note. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 59(6), 724-725. doi:10.1016/j.bjoms.2020.09.022
A new classification of mandibular fractures.
Brown, J. S., Khan, A., Wareing, S., & Schache, A. G. (2021). A new classification of mandibular fractures.. International Journal of Oral and Maxillofacial Surgery. doi:10.1016/j.ijom.2021.02.012
Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study
Nepogodiev, D., Simoes, J. F. F., Li, E., Picciochi, M., Glasbey, J. C., Baiocchi, G., . . . Ramos-De la Medina, A. (2021). Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. ANAESTHESIA, 76(6), 748-758. doi:10.1111/anae.15458
Clinical characteristics, treatment intent, and outcome in a consecutive 10-year cohort of oral cancer patients aged 75 years and older*
Chieng, C. Y., Davies, A., Lowe, D., Bekiroglu, F., Khattak, O., Schache, A., . . . Rogers, S. N. (2021). Clinical characteristics, treatment intent, and outcome in a consecutive 10-year cohort of oral cancer patients aged 75 years and older*. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 59(3), 303-311. doi:10.1016/j.bjoms.2020.08.086
COVID-19-related absence among surgeons: development of an international surgical workforce prediction model
Li, E. (2021). COVID-19-related absence among surgeons: development of an international surgical workforce prediction model. BJS OPEN, 5(2). doi:10.1093/bjsopen/zraa021
UK Head and neck cancer surgical capacity during the second wave of the COVID-19
Schache, A. (n.d.). UK Head and neck cancer surgical capacity during the second wave of the COVID-19. Clinical Otolaryngology. doi:10.1111/coa.13749
British Association of Head and Neck Oncologists (BAHNO) standards 2020
Schache, A., Kerawala, C., Ahmed, O., Brennan, P. A., Cook, F., Garrett, M., . . . Winter, S. C. (2021). British Association of Head and Neck Oncologists (BAHNO) standards 2020. JOURNAL OF ORAL PATHOLOGY & MEDICINE, 50(3), 262-273. doi:10.1111/jop.13161
Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic
Glasbey, J. C., Omar, O., Nepogodiev, D., Minaya-Bravo, A., Bankhead-Kendall, B. K., Fiore, M., . . . Scasso, S. (2021). Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. BRITISH JOURNAL OF SURGERY, 108(1), 88-96. doi:10.1093/bjs/znaa051
Elective Cancer Surgery in COVID-19–Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study
Glasbey, J. C., & Bhangu, A. (n.d.). Elective Cancer Surgery in COVID-19–Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study. Journal of Clinical Oncology, JCO.20.01933. doi:10.1200/jco.20.01933
Imaging advances in oral cavity cancer and perspectives from a population in need: Consensus from the UK-India oral cancer imaging group
Subramaniam, N., Poptani, H., Schache, A., Bhat, V., Iyer, S., Sunil, H. V., . . . Mahajan, A. (2021). Imaging advances in oral cavity cancer and perspectives from a population in need: Consensus from the UK-India oral cancer imaging group. JOURNAL OF HEAD & NECK PHYSICIANS AND SURGEONS, 9(1), 4-12. doi:10.4103/jhnps.jhnps_10_21
2020
Head and neck cancer surgery during the COVID-19 pandemic: an international, multicentre, observational cohort study
Shaw, R., Schache, A., Jackson, R., & Ciccone, S. (2020). Head and neck cancer surgery during the COVID-19 pandemic: an international, multicentre, observational cohort study. Cancer. doi:10.1002/cncr.33320
Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: baseline results in a cluster preference randomised controlled trial
Rogers, S. N., Allmark, C., Bekiroglu, F., Edwards, R. T., Fabbroni, G., Flavel, R., . . . Kanatas, A. (2020). Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: baseline results in a cluster preference randomised controlled trial. In EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY Vol. 277 (pp. 3435-3447). doi:10.1007/s00405-020-06077-6
Should we be re-starting elective surgery?
Simoes, J., & Bhangu, A. (2020). Should we be re-starting elective surgery?. ANAESTHESIA, 75(12), 1563-1565. doi:10.1111/anae.15296
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
Bhangu, A. (2021). Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic. COLORECTAL DISEASE, 23(3), 732-749. doi:10.1111/codi.15431
The relevance of surgical margins in clinically early oral squamous cell carcinoma.
Bajwa, M. S., Houghton, D., Java, K., Triantafyllou, A., Khattak, O., Bekiroglu, F., . . . Shaw, R. J. (2020). The relevance of surgical margins in clinically early oral squamous cell carcinoma.. Oral oncology, 110, 104913. doi:10.1016/j.oraloncology.2020.104913
Delaying surgery for patients with a previous SARS-CoV-2 infection
Delaying surgery for patients with a previous SARS-CoV-2 infection (2020). BRITISH JOURNAL OF SURGERY, 107(12), E601-E602. doi:10.1002/bjs.12050
Elective surgery cancellations due to theCOVID-19 pandemic: global predictive modelling to inform surgical recovery plans
Nepogodiev, D., Omar, O. M., Glasbey, J. C., Li, E., Simoes, J. F. F., Abbott, T. E. F., . . . Poelaert, J. (2020). Elective surgery cancellations due to theCOVID-19 pandemic: global predictive modelling to inform surgical recovery plans. BRITISH JOURNAL OF SURGERY, 107(11), 1440-1449. doi:10.1002/bjs.11746
Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study
Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study (2020). LANCET, 396(10243), 27-38. doi:10.1016/S0140-6736(20)31182-X
Determining the effectiveness of fibrin sealants in reducing complications in patients undergoing lateral neck dissection (DEFeND): Study protocol for a randomised external pilot trial
Bajwa, M. S., Carruthers, S., Hanson, R., Jackson, R., Braithwaite, C., Edwards, M., . . . Schache, A. G. (2020). Determining the effectiveness of fibrin sealants in reducing complications in patients undergoing lateral neck dissection (DEFeND): Study protocol for a randomised external pilot trial. Pilot and Feasibility Studies, 6(1). doi:10.1186/s40814-020-00618-w
Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines
Greaney-Davies, F. S. T., Risk, J., Robinson, M., Liloglou, T., Shaw, R., & Schache, A. (2020). Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines. Oral Oncology, 103. doi:10.1016/j.oraloncology.2020.104613
Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland
Craig, S. G., Anderson, L. A., Moran, M., Graham, L., Currie, K., Rooney, K., . . . James, J. A. (2020). Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 29(1), 31-38. doi:10.1158/1055-9965.EPI-19-0538
Overexpression of <i>HURP</i> mRNA in head and neck carcinoma and association with <i>in vitro</i> response to vinorelbine
Al-Khafaji, A. S. K., Pantazi, P., Acha-Sagredo, A., Schache, A., Risk, J. M., Shaw, R. J., & Liloglou, T. (2020). Overexpression of <i>HURP</i> mRNA in head and neck carcinoma and association with <i>in vitro</i> response to vinorelbine. ONCOLOGY LETTERS, 19(3), 2502-2507. doi:10.3892/ol.2020.11339
2019
Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck
Carter, R. J., Milani, M., Butterworth, M., Alotibi, A., Harper, N., Yedida, G., . . . Varadarajan, S. (2019). Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death and Disease, 10(12). doi:10.1038/s41419-019-2150-8
Health-related quality of life in patients with T1N0 oral squamous cell carcinoma: selective neck dissection compared with wait and watch surveillance
McDonald, C., Lowe, D., Bekiroglu, F., Schache, A., Shaw, R., & Rogers, S. N. (2019). Health-related quality of life in patients with T1N0 oral squamous cell carcinoma: selective neck dissection compared with wait and watch surveillance. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 57(7), 649-654. doi:10.1016/j.bjoms.2019.05.021
Hypoxia and HPV Status in Oropharyngeal Squamous Cell Carcinoma
Ben Salah, K., Triantafyllou, A., Schache, A., Shaw, R. J., & Risk, J. M. (2019). Hypoxia and HPV Status in Oropharyngeal Squamous Cell Carcinoma. In JOURNAL OF PATHOLOGY Vol. 249 (pp. S36). Retrieved from https://www.webofscience.com/
Integration of Checkpoint Inhibitors into the Management of Locally Advanced Head and Neck Cancer - Future Perspectives
Brooker, R. C., Sacco, J. J., & Schache, A. G. (2019). Integration of Checkpoint Inhibitors into the Management of Locally Advanced Head and Neck Cancer - Future Perspectives. Clinical Oncology, 31(7), 424-431. doi:10.1016/j.clon.2019.04.011
Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach
Craig, S. G., Anderson, L. A., Schache, A. G., Moran, M., Graham, L., Currie, K., . . . James, J. A. (2019). Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach. BRITISH JOURNAL OF CANCER, 120(8), 827-833. doi:10.1038/s41416-019-0414-9
2018
Metabolic Pathways and Cell Proliferation in the Advancing Front of Oropharyngeal Squamous Cell Carcinoma
Ben Salah, K., Triantafyllou, A., Schache, A., Shaw, R., & Risk, J. (2018). Metabolic Pathways and Cell Proliferation in the Advancing Front of Oropharyngeal Squamous Cell Carcinoma. In BRITISH JOURNAL OF CANCER Vol. 119 (pp. 29-30). Retrieved from https://www.webofscience.com/
Molecular pathogenesis of proliferative verrucous leukoplakia: a systematic review
Okoturo, E. M., Risk, J. M., Schache, A. G., Shaw, R. J., & Boyd, M. T. (2018). Molecular pathogenesis of proliferative verrucous leukoplakia: a systematic review. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 56(09), 780-785. doi:10.1016/j.bjoms.2018.08.010
Socioeconomic Deprivation and the Burden of Head and Neck Cancer- Regional variations of Incidence and Mortality in Merseyside and Cheshire, North West, England
Taib, B. G., Oakley, J., Dailey, Y., Hodge, I., Wright, P., du Plessis, R., . . . Jones, T. (2018). Socioeconomic Deprivation and the Burden of Head and Neck Cancer- Regional variations of Incidence and Mortality in Merseyside and Cheshire, North West, England. Clinical Otolaryngology, 43(3), 846-853. doi:10.1111/coa.13067
A randomised, double-blind, placebo-controlled phase IIa trial of AMG319 given orally as neoadjuvant therapy in patients with human papillomavirus (HPV) positive and negative head and neck squamous cell carcinoma (HNSCC).
Ottensmeier, C. H. H., Jones, T., Sacco, J. J., McCaul, J. A., Brennan, P., Paterson, C., . . . King, E. (2018). A randomised, double-blind, placebo-controlled phase IIa trial of AMG319 given orally as neoadjuvant therapy in patients with human papillomavirus (HPV) positive and negative head and neck squamous cell carcinoma (HNSCC).. In JOURNAL OF CLINICAL ONCOLOGY Vol. 36. doi:10.1200/JCO.2018.36.15_suppl.6068
Oral cavity malignancy
Smith, W. P., & Schache, A. G. (2018). Oral cavity malignancy. In Edition (pp. 760-775). doi:10.1201/9781315111087-48
2017
Head and neck reconstruction with free flaps based on the thoracodorsal system
O'Connell, J. E., Bajwa, M. S., Schache, A. G., & Shaw, R. J. (2017). Head and neck reconstruction with free flaps based on the thoracodorsal system. ORAL ONCOLOGY, 75, 46-53. doi:10.1016/j.oraloncology.2017.10.019
Fibrin sealants in soft tissue surgery of the head and neck: A systematic review and meta‐analysis of randomised controlled trials
Bajwa, M. S., Tudur-Smith, C., Shaw, R. J., & Schache, A. G. (2017). Fibrin sealants in soft tissue surgery of the head and neck: A systematic review and meta‐analysis of randomised controlled trials. Clinical Otolaryngology, 42(6), 1141-1152. doi:10.1111/coa.12837
Sentinel lymph node biopsy for oral squamous cell carcinoma. Where are we now?
Schilling, C., Shaw, R., Schache, A., McMahon, J., Chegini, S., Kerawala, C., & McGurk, M. (2017). Sentinel lymph node biopsy for oral squamous cell carcinoma. Where are we now?. British Journal of Oral and Maxillofacial Surgery, 55(8), 757-762. doi:10.1016/j.bjoms.2017.07.007
Management of proliferative verrucous leukoplakia: Justification for a conservative approach.
Borgna, S. C., Clarke, P. T., Schache, A. G., Lowe, D., Ho, M. W., McCarthy, C. E., . . . Shaw, R. J. (2017). Management of proliferative verrucous leukoplakia: Justification for a conservative approach.. Head & neck, 39(10), 1997-2003. doi:10.1002/hed.24845
Modulating the DNA Damage Response to Improve Treatment Response in Cervical Cancer
Cossar, L. H., Schache, A. G., Risk, J. M., Sacco, J. J., Jones, N. J., & Lord, R. (2017). Modulating the DNA Damage Response to Improve Treatment Response in Cervical Cancer. Clinical Oncology, 29(9), 626-634. doi:10.1016/j.clon.2017.03.002
Mandibular reconstruction with vascularised bone flaps: a systematic review over 25 years
Brown, J. S., Lowe, D., Kanatas, A., & Schache, A. (2017). Mandibular reconstruction with vascularised bone flaps: a systematic review over 25 years. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 55(2), 113-126. doi:10.1016/j.bjoms.2016.12.010
Molecular Biology of Human Papillomavirus–Mediated Head and Neck Cancer
Schache, A. G. (2017). Molecular Biology of Human Papillomavirus–Mediated Head and Neck Cancer. In Maxillofacial Surgery (pp. 275-284). Elsevier. doi:10.1016/b978-0-7020-6056-4.00016-2
2016
HPV-related oropharyngeal cancer in the United Kingdom: an evolution in understanding of disease etiology
Schache, A. G., Powell, N. G., Cuschieri, K. S., Robinson, M., Leary, S., Mehanna, H., . . . Jones, T. M. (2016). HPV-related oropharyngeal cancer in the United Kingdom: an evolution in understanding of disease etiology. Cancer research, 76(22), 6598-6606. doi:10.1158/0008-5472.CAN-16-0633
Liverpool Opinion on Unfavorable Results in Microsurgical Head and Neck Reconstruction Lessons Learned
Brown, J., Schache, A., & Butterworth, C. (2016). Liverpool Opinion on Unfavorable Results in Microsurgical Head and Neck Reconstruction Lessons Learned. CLINICS IN PLASTIC SURGERY, 43(4), 707-+. doi:10.1016/j.cps.2016.05.007
Socioeconomic Deprivation and the Burden of Head and Neck Cancer in Merseyside and Cheshire
Taib, B. G., Oakley, J., Dailey, Y., Hodge, I., Wright, P., du Plessis, R., . . . Jones, T. (2016, November 6). Socioeconomic Deprivation and the Burden of Head and Neck Cancer in Merseyside and Cheshire. In National Cancer Research Institute Conference. BT Convention Centre, Liverpool, UK.
2015
The use of Tisseel™ fibrin sealant in selective neck dissection - a retrospective study in a tertiary Head and Neck Surgery centre
Mushi, E., Kinshuck, A., Svecova, N., Schache, A., Jones, T. M., Tandon, S., & Lancaster, J. (2015). The use of Tisseel™ fibrin sealant in selective neck dissection - a retrospective study in a tertiary Head and Neck Surgery centre. CLINICAL OTOLARYNGOLOGY, 40(2), 93-97. doi:10.1111/coa.12322
2014
Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related.
Upile, N., Shaw, R., Jones, T., Goodyear, P., Liloglou, L., Risk, J., . . . Schache, A. (2014). Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related.. The Laryngoscope, 124(12), 2739-2744. doi:10.1002/lary.24828
Human Papillomavirus Testing in Head and Neck Squamous Cell Carcinoma: Best Practice for Diagnosis
Schache, A., Croud, J., Robinson, M., & Thavaraj, S. (2014). Human Papillomavirus Testing in Head and Neck Squamous Cell Carcinoma: Best Practice for Diagnosis. In HISTOPATHOLOGY: METHODS AND PROTOCOLS (Vol. 1180, pp. 237-255). doi:10.1007/978-1-4939-1050-2_13
2013
Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma
Schache, A. G., Liloglou, T., Risk, J. M., Jones, T. M., Ma, X. -J., Wang, H., . . . Robinson, M. (2013). Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(6), 1332-1339. doi:10.1038/bjc.2013.63
The epigenetic landscape of oral squamous cell carcinoma
Jithesh, P. V., Risk, J. M., Schache, A. G., Dhanda, J., Lane, B., Liloglou, T., & Shaw, R. J. (2013). The epigenetic landscape of oral squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(2), 370-379. doi:10.1038/bjc.2012.568
The molecular and clinical implications of human papillomavirus-16 mediated oropharyngeal squamous cell carcinoma
Schache, A. G. (2013). The molecular and clinical implications of human papillomavirus-16 mediated oropharyngeal squamous cell carcinoma.
2012
HPV specific testing: a requirement for oropharyngeal squamous cell carcinoma patients.
Robinson, M., Schache, A., Sloan, P., & Thavaraj, S. (2012). HPV specific testing: a requirement for oropharyngeal squamous cell carcinoma patients.. Head and neck pathology, 6 Suppl 1, S83-S90. doi:10.1007/s12105-012-0370-7
Epidermal Growth Factor Receptor and the Changing Face of Oropharyngeal Cancer
Gilbert, D. C., Simcock, R., Schache, A., & Shaw, R. (2012). Epidermal Growth Factor Receptor and the Changing Face of Oropharyngeal Cancer. JOURNAL OF CLINICAL ONCOLOGY, 30(8), 890-891. doi:10.1200/JCO.2011.40.4848
2011
HPV associated Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Upile, N., Schache, A., Shaw, R., & Jones, T. M. (2011). HPV associated Oropharyngeal Squamous Cell Carcinoma (OPSCC). Otorhinolaryngologist, 4(2), 57-61.
Reply to: Clinically Significant Human Papilloma Virus in Squamous Cell Carcinoma of the Head and Neck in UK Practice
Schache, A. G., & Shaw, R. J. (2011). Reply to: Clinically Significant Human Papilloma Virus in Squamous Cell Carcinoma of the Head and Neck in UK Practice. CLINICAL ONCOLOGY, 23(10), 718. doi:10.1016/j.clon.2011.09.003
Comparing HPV vaccines Changing face of HPV related cancer in the UK
Schache, A. G., Simcock, R., Gilbert, D. C., & Shaw, R. J. (2011). Comparing HPV vaccines Changing face of HPV related cancer in the UK. BRITISH MEDICAL JOURNAL, 343. doi:10.1136/bmj.d6675
Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination
Schache, A. G., Liloglou, T., Risk, J. M., Filia, A., Jones, T. M., Sheard, J., . . . Shaw, R. J. (2011). Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination. CLINICAL CANCER RESEARCH, 17(19), 6262-6271. doi:10.1158/1078-0432.CCR-11-0388
2010
Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma
Schache, A. G., Hall, G., Woolgar, J. A., Nikolaidis, G., Triantafyllou, A., Lowe, D., . . . Liloglou, T. (2010). Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma. BRITISH JOURNAL OF CANCER, 103(12), 1846-1851. doi:10.1038/sj.bjc.6605953
2009
Total mandibular subapical osteotomy: modification of the technique
Mohammed-Ali, R. I., Schache, A., Walsh, S., & Sneddon, K. (2009). Total mandibular subapical osteotomy: modification of the technique. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 47(8), 629-630. doi:10.1016/j.bjoms.2008.11.017
Predictors of swallowing outcome in patients treated with surgery and radiotherapy for advanced oral and oropharyngeal cancer
Schache, A. G., Lieger, O., Rogers, P., Kelly, A., Newman, L., & Kalavrezos, N. (2009). Predictors of swallowing outcome in patients treated with surgery and radiotherapy for advanced oral and oropharyngeal cancer. ORAL ONCOLOGY, 45(9), 803-808. doi:10.1016/j.oraloncology.2008.12.010
2008
Osseointegrated implants: A potential route of entry for squamous cell carcinoma of the mandible
Schache, A., Thavaraj, S., & Kalavrezos, N. (2008). Osseointegrated implants: A potential route of entry for squamous cell carcinoma of the mandible. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 46(5), 397-399. doi:10.1016/j.bjoms.2007.09.009
2007
Low dose metronomic oral cyclophosphamide for hormone resistant prostate cancer: A phase II study
Lord, R., Nair, S., Schache, A., Spicer, J., Somaihah, N., Khoo, V., & Pandha, H. (2007). Low dose metronomic oral cyclophosphamide for hormone resistant prostate cancer: A phase II study. JOURNAL OF UROLOGY, 177(6), 2136-2140. doi:10.1016/j.juro.2007.01.143