Publications
2024
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19
Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Cornish, K., Huo, J., Jones, L., Sharma, P., Thrush, J. W., Abdelkarim, S., . . . Owens, R. J. (2024). Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.. Open biology, 14(6), 230252. doi:10.1098/rsob.230252
Vascular changes in association with non-suppurative encephalitis in SARS-CoV-2-infected K18-hACE2 mice
De Neck, S., Hetzel, U., Parul, S., Bentley, E. G., Kirby, A., Seehusen, F., . . . Kipar, A. (2024). Vascular changes in association with non-suppurative encephalitis in SARS-CoV-2-infected K18-hACE2 mice. Journal of Comparative Pathology, 210, 59. doi:10.1016/j.jcpa.2024.03.035
Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression.
Zhuang, X., Gallo, G., Sharma, P., Ha, J., Magri, A., Borrmann, H., . . . McKeating, J. A. (2024). Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression.. iScience, 27(1), 108763. doi:10.1016/j.isci.2023.108763
2023
Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression
Recombinant SARS-CoV-2 lacking initiating and internal methionine codons within ORF10 is attenuated<i>in vivo</i>
The Stereotypic Response of the Pulmonary Vasculature to Respiratory Viral Infections: Findings in Mouse Models of SARS-CoV-2, Influenza A and Gammaherpesvirus Infections
De Neck, S., Penrice-Randal, R., Clark, J. J., Sharma, P., Bentley, E. G., Kirby, A., . . . Kipar, A. (2023). The Stereotypic Response of the Pulmonary Vasculature to Respiratory Viral Infections: Findings in Mouse Models of SARS-CoV-2, Influenza A and Gammaherpesvirus Infections. Viruses, 15(8), 1637. doi:10.3390/v15081637
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2
Gaynor, K. U. U., Vaysburd, M., Harman, M. A. J., Albecka, A., Jeffrey, P., Beswick, P., . . . James, L. C. C. (2023). Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2. NATURE COMMUNICATIONS, 14(1). doi:10.1038/s41467-023-39158-1
Myosin Heavy Chain 9 is Involved in Murine Gammaherpesvirus 68 Infection and as a Drug Target for Antiviral Infection
2022
Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse
Seehusen, F., Clark, J. J., Sharma, P., Bentley, E. G., Kirby, A., Subramaniam, K., . . . Kipar, A. (2022). Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse. VIRUSES-BASEL, 14(5). doi:10.3390/v14051020
2021
2020
Pharmacodynamics of the Novel Metallo-beta-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae
Das, S., Johnson, A., McEntee, L., Farrington, N., Kirby, A., Unsworth, J., . . . Hope, W. (2020). Pharmacodynamics of the Novel Metallo-beta-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae. Antimicrobial Agents and Chemotherapy, 64(11). doi:10.1128/AAC.01076-20
Pharmacodynamics of the Novel Metallo-β-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
Das, S., Johnson, A., McEntee, L., Farrington, N., Kirby, A., Unsworth, J., . . . Hope, W. (2020). Pharmacodynamics of the Novel Metallo-β-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.. Antimicrob Agents Chemother, 64(11). doi:10.1128/AAC.01076-20