Developing the Long-acting Pipeline

Have you ever wondered how scientists use your donated blood?Have you ever wondered how scientists use your donated blood?

Have you ever wondered how scientists use your donated blood?

It’s World Blood Donor Day, and we wanted to let you know how we use blood, donated by healthy volunteers, within the Centre of Excellence for Long-acting Therapeutics (CELT) and how it’s helping to eliminate devastating diseases around the world.

Posted on: 14 June 2024

How does CELT's immunology work consider ageing?How does CELT

How does CELT's immunology work consider ageing?

29 April each year is the International Day of Immunology, to celebrate the benefits of immunology research.

Posted on: 29 April 2024

CELT Celebrates 2024's International Day of Women and Girls in ScienceCELT Celebrates 2024

CELT Celebrates 2024's International Day of Women and Girls in Science

Sunday 11 February was International Day of Women and Girls in Science. This day was implemented in 2015 by UNESCO and UN-Women to celebrate the critical contribution of women and girls to all fields of science and technology.

Posted on: 12 February 2024

The Long-acting Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum (LAMP) StudyThe Long-acting Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum (LAMP) Study

The Long-acting Antipsychotics for Mental Ill-Health in Pregnancy and Postpartum (LAMP) Study

I’m Georgia Duffy, a PhD student in the Perinatal Pharmacology Group within the Centre of Excellence for Long-acting Therapeutics (CELT). I am being supervised by Dr Adeniyi Olagunju and my project is focused is Long-acting Antipsychotics for Mental Ill-health in Pregnancy and Postpartum (LAMP). My project is part of the LAMP study which is a multi-centre cohort study. Its overarching aim is to advance our understanding of the pharmacology of long-acting injectable antipsychotics (LAIA) during pregnancy and lactation.

Posted on: 12 May 2023

Creating Dissolvable Microneedle Arrays as an Alternative Drug Delivery System to Treat GlaucomaCreating Dissolvable Microneedle Arrays as an Alternative Drug Delivery System to Treat Glaucoma

Creating Dissolvable Microneedle Arrays as an Alternative Drug Delivery System to Treat Glaucoma

I’m Elliot Croft, a PhD student based in the Department of Chemistry. I obtained an MChem degree in Medicinal Chemistry with Pharmacology at the University of Liverpool. During my undergraduate studies, I undertook research projects focusing on polymer synthesis and controlling the size of inorganic nanoparticles for targeted drug delivery. Now, my research focuses on the development of bespoke dissolvable microneedle arrays (DMNs) for the treatment of glaucoma which provide sustained drug delivery which cannot be achieved using the typical treatment method – eye drops.

Posted on: 22 February 2023

Assessing the preclinical development of long-acting biodegradable implantsAssessing the preclinical development of long-acting biodegradable implants

Assessing the preclinical development of long-acting biodegradable implants

I’m Dr Meg Neary, a postdoctoral research associate at the Centre of Excellence for Long-acting therapeutics (CELT). My work involves preclinical development of long-acting antiretroviral therapy (LA ART). LA ART provides exposure to a drug over a long period of time. This means instead of taking oral tablets, the contents of which are eliminated by the body over a very short period of time, patients can take LA ART and have effective exposure to the same drug concentration for a period of weeks, months or years.

Posted on: 31 January 2023

Data analysis, Modelling and accelerating development of Long-acting therapeuticsData analysis, Modelling and accelerating development of Long-acting therapeutics

Data analysis, Modelling and accelerating development of Long-acting therapeutics

Data analysis and modelling in pharmacology is an essential technique for understanding and predicting the effects of different drugs on the human body. It allows researchers to interpret large amounts of data from clinical trials, lab experiments, and other sources, in order to understand how drugs interact with different biological systems and how they might be used to treat various diseases or conditions. It is an important part of the drug development process, and helps researchers optimise drug therapies and improve patient outcomes.

Posted on: 13 January 2023

Taking control of the HIV epidemic – How long-acting injectables can help reach ambitious targetsTaking control of the HIV epidemic – How long-acting injectables can help reach ambitious targets

Taking control of the HIV epidemic – How long-acting injectables can help reach ambitious targets

HIV continues to be a global public health concern with approximately 40 million people living with HIV infection in 2021 globally – the epidemic has sadly claimed millions of lives all over the world.

Posted on: 12 September 2022

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