Netropsin-DNA complex

(Netropsin.pdb)

The window to the left shows a crystallographic structure of the minor groove-binding drug, netropin bound to a double-stranded DNA oligonucleotide. The details of the structure and the relevant papers can be found in the header to the coordinate file. Click and drag in the window to rotate the structure in real time. If you need to find out more about manipulating the structure, which is generated by a Plugin called Chime, go to the following description of How to use Chime.

The buttons below allow you to manipulate the structure in specific ways.

Those at the top are generic for any structure, and allow you to rotate the structure in 90 degree increments, and to change the display of the atoms. The Reset button allows you to start again if everything goes horribly wrong!

In the centre is a set of colour buttons for you to colour in all or part of the structure for emphasis, for example, having 'selected' a portion of it.

At the bottom are buttons specific for this structure, which allow you to select the netropsin, the DNA, or restrict your view to the DNA or Netropsin alone. At any point you can click-drag to rotate the structure. Remember, if in doubt, press Reset.

Go To Buttons

Reset	Reset zoom	Select all
Rotate x 90	Rotate y 90	Rotate z 90
Wireframe	Backbone	Spacefill
Sticks	Ball & Stick
Dots on	Dots off

RED	GREEN	BLUE
CYAN	MAGENTA	YELLOW
WHITE	BLACK	CPK

Select Netropsin	Select DNA	Show DNA alone
Restore Netropsin	Show Netropsin alone	Restore DNA