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BIOL404 - Oncogenes and Cancer

Module co-ordinator : Dr. B.R. Barraclough

Location

Life Sciences 5th Floor

Times

Thursday, Friday: 09.00, also Wednesday, weeks 22 & 23

Week

Lecture
Content

13

Dr. B.R. Barraclough

Introduction and aims

Study skills helpful for the course.

13-15

4
Dr. J.A. Smith

Introduction to growth factors and their receptors

Growth factors and the control of growth

Growth factor receptors.

Intracellular signals.

Tutorial: growth factors and relation to cancer.

15-16

3
Dr. M.R.H. White

Introduction to viruses including HIV

DNA viruses

RNA viruses

Human immunodeficiency (AIDS) virus.

17-18

4
Dr. C.D. Green

Introduction to oncogenes

Assays for oncogenes

Oncogenes and normal cellular genes

Anti-oncogenes and tumour suppressor genes.

Tutorial: Viruses and oncogenes (+ Dr. M.R.H. White)

19

2
Prof. P.S. Rudland

Introduction to the biology of human cancer

Biology of human cancer

Classification of human tumours

20

1
Mr. J. Winstanley (Consultant Surgeon, NMGH)

Cancer: the view from the clinic

20-23

7
Dr. B.R. Barraclough

Oncogenes and human cancer

DNA damage and cellular mechanisms for its repair

Mutations in the development of leukaemias/Burkitt’s lymphoma

Mutation and the common cancers

Tumour suppressor genes

Metastasis

Gene transfer and deletion techniques in the development of experimental models of cancer.

Oncogenes and apoptosis. Review of the course. Feedback; the examination

 

23

1
Dr. C.D. Green

Hormones and Cancer

23

1
Dr. B.R. Barraclough

Review of the course. Feedback; the examination

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