BIOL316 - Molecular Immunology

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BIOL316 - Molecular Immunology

Module co-ordinator : Dr. B.F. Flanagan, Department of Immunology

Location

Donnan Seminar Room

Times

Monday, Thursday: 11.00

Week
Lecture Content

18
1 Dr G.S. Vince
An Introductin to Immunology

Components of the immune system, the importance of non-self discrimination and specific recognition of antigens.

19-20
3 Dr. B.F. Flanagan
Antibody Structure

Stucture and function of the antibody classes. Antibody production and clonal selection.

Antibody Gene Rearrangments

Genetic mechanisms of antibody gene rearrangement. Why, How and When?

21
1 Dr. P.J. McLaughlin
Genetic Engineering and Antibody Production

Monoclonal and genetically engineered antibodies for treating human disease.

21
1 Dr. B.F. Flanagan
Genetics of the Major Histocompatibility Complex (MHC)

Structure of the MHC class I and class II molecules, genetics and disease associations.

22
2 Dr. S.E. Christmas
Recognition of MHC Plus Peptide by T Cells

T cell recognition MHC. Genetic variation of the immune response.

T Cell Gene Rearrangements

Mechanisms of T cell gene rearrangement, and the recombinase genes.

22
1 Dr. P.J. McLaughlin
Cytokines and their Regulation

Molecules in the control of immunity and inflammation.

23
2 Dr. S.E. Christmas
Immunological Tolerance. B and T Cell Tolerance

Positive and negative selection. The use of transgenic animals as models of B and T cell tolerance.

Molecular Immunology and Disease

Mechanism of immunologically mediated disease and disease models.

CONTENTS | NEXT PAGE

Location	Donnan Seminar Room
Times	Monday, Thursday: 11.00

Week	Lecture	Content
18	1	Dr G.S. Vince An Introductin to Immunology Components of the immune system, the importance of non-self discrimination and specific recognition of antigens.
19-20	3	Dr. B.F. Flanagan Antibody Structure Stucture and function of the antibody classes. Antibody production and clonal selection. Antibody Gene Rearrangments Genetic mechanisms of antibody gene rearrangement. Why, How and When?
21	1	Dr. P.J. McLaughlin Genetic Engineering and Antibody Production Monoclonal and genetically engineered antibodies for treating human disease.
21	1	Dr. B.F. Flanagan Genetics of the Major Histocompatibility Complex (MHC) Structure of the MHC class I and class II molecules, genetics and disease associations.
22	2	Dr. S.E. Christmas Recognition of MHC Plus Peptide by T Cells T cell recognition MHC. Genetic variation of the immune response. T Cell Gene Rearrangements Mechanisms of T cell gene rearrangement, and the recombinase genes.
22	1	Dr. P.J. McLaughlin Cytokines and their Regulation Molecules in the control of immunity and inflammation.
23	2	Dr. S.E. Christmas Immunological Tolerance. B and T Cell Tolerance Positive and negative selection. The use of transgenic animals as models of B and T cell tolerance. Molecular Immunology and Disease Mechanism of immunologically mediated disease and disease models.