Advanced Biological Sciences MRes Research Projects 24/25

If you’re looking to move into a career in science, whether in academia, industry or biomedicine research, the Advanced Biological Sciences MRes will enable you to develop advanced knowledge, skills and understanding in biological sciences. A year-long research project, under the supervision of an expert tutor, forms the central part of the course. Selecting the right project is a key decision and we’ll help you choose a topic relevant to your interests and career plans.

To discuss your research project please email the programme director Dr Svetlana Antonyuk

Project TitleProject TypeSupervisor
Applying Deep Learning-based methods for protein structure prediction. Desk Professor Dan Rigden
Next generation approach for annotating genomes using machine learning. Desk Professor Andy Jones
Mapping post-translational modifications across the Tree of Life. Desk Professor Andy Jones
Body shape and size evolution in tetrapods. Desk Dr Alice Maher
Understanding plasmid evolution through computational biology. Desk Dr James Hall
Climate change and Infectious Disease Outbreaks in Africa and/or Asia. Desk Dr Louise Kelly-Hope
What do animals gain from choosing the right mate? Desk Dr Liam Dougherty
Use of Artificial Intelligence in analysis of endoscopic images following complete response in Rectal Cancer. Desk Dr Muhammad Ahsan Javed
Combining adaptation and physiology to predict the pace of life in diverse animals. Desk Professor David Atkinson
Selective breeding and gait in dogs. Laboratory Professor Karl Bates
Understanding motion in the healthy human wrist. Laboratory Professor Karl Bates
Exploiting the plant root microbiome to promote crop health. Laboratory Dr Daniel Leybourne
What drives re-expression of the latent toolbox of meiotic oncogenes in cancer? Laboratory Dr Urszula McClurg
Understanding the phenotype of genetically induced obesity and cerebellum abnormalities. Laboratory Dr Urszula McClurg
Is meiotic TEX12 a novel regulator of centrosome amplifications in cancer? Laboratory Dr Urszula McClurg
Laminin alternative splicing in cancer - regulation and functional consequences. Laboratory Dr Kevin Hamill
Laminin N Terminus alpha31 signalling studies. Laboratory Dr Kevin Hamill
MuscleGaIn (Muscle-Gut axis Investigation): role or exercise and nutrition as hallmarks of ageing, frailty and muscle health. Laboratory Dr Masoud Isanejad
Microbial evolution, mobile genetic elements, and horizontal gene transfer. Laboratory Dr James Hall
A molecular approach to dissect NF-kappaB signalling in mouse embryonic stem cells. Laboratory Dr David Turner
Mechanisms controlling gene expression in hypoxia and/or inflammation. Laboratory Professor Sonia Rocha
Investigating symbiotic interactions between insects and microbes. Laboratory Professor Greg Hurst
Jekyll and Hyde: Modelling the interaction between insects and heritable microbes that have both beneficial and parasitic phenotypes. Laboratory Professor Greg Hurst
Evolutionary resistance to climate change in plant populations exposed to chronic climate treatments. Laboratory Dr Raj Whitlock
Functional and morphological variation in the masticatory apparatus in primates. Laboratory Dr Alana Sharp
Building giants – soft and hard tissue relationships during skull growth in large mammals. Laboratory Dr Alana Sharp
The evolution of physiological adaptations to toxins. Laboratory Dr Hannah Rowland
Climate change impacts on beneficial species interactions in agriculture. Laboratory Dr Sharon Zytynska
Understanding microbial signalling in the rhizosphere to build healthier soils. Laboratory Dr Sharon Zytynska
Alpaca and llama anatomy. Laboratory Karin Mueller & Dr Zeeshan Durrani
Understanding norovirus polyprotein dynamics. Laboratory Dr Edward Emmott
Exploring the effect of depleting host deaminases on coronavirus replication and transcription. Laboratory Dr Edward Emmott
Bioengineering and Reprogramming of self-assembling protein organelles. Laboratory Professor Luning Liu
Role of epithelial stem progenitor cells in the endometrium of women with gynaecological pathologies. Laboratory Professor Dharani Hapangama
Evaluating the impact of microplastics on kidney cells. Laboratory Dr Louise Oni
The role of the endosymbiont in trypanosomatid parasite infection in Drosophila. Laboratory Dr Venera Tyukmaeva
Application of structure-based drug discovery for treatment of Amyotrophic lateral sclerosis (ALS). Laboratory Dr Svetlana Antonyuk
Do cell clocks drive age-associated tissue stiffness in the eye. Laboratory Dr Carl Sheridan
What extracellular changes occur in the ageing retina? Laboratory Dr Victoria Kearns
Molecular evolution of taste perception and feeding ecology in mammals. Laboratory Professor Soraya Shirazi-Beechey & Dr Michael Berenbrink
Exploring the Liver Homology Receptor-1 (LHR-1) pathway in the maintenance of gut mucosal health. Laboratory Professor Barry Campbell
Understanding costs of phenotypic plasticity in the Water flea, Daphnia magna. Laboratory Dr Stew Plaistow
Ecological and evolutionary consequences of nanoplastic pollution. Laboratory Dr Stew Plaistow
Understanding costs of phenotypic plasticity. Laboratory Dr Stew Plaistow
Fibrillin-1 loss in musculoskeletal health across the life course (growth and ageing). Laboratory Dr Blandine Poulet
Characterising interaction between cell-surface receptor LRP1 and disease-associated molecules. Laboratory Dr Kazuhiro Yamamoto
Evolutionary resistance to climate change in plant populations exposed to chronic climate treatments. Laboratory Dr Raj Whitlock
Genomic responses to climate change in an ecological model plant species. Laboratory Dr Raj Whitlock
Impacts of climate change on plant-soil co-adaptation and ecosystem functioning. Laboratory Dr Raj Whitlock
Evolution of physiological adaptations to toxins. Laboratory Dr Hannah Rowland
Scaling By Death During Adult Organ Growth. Laboratory Dr Marisa Merino
Influence of Extracellular Matrix on Induced Pluripotent Stem Cell Differentiation into Corneal Endothelial Cells for Cell Therapy. Laboratory Emine Bilir
Role of epithelial stem progenitor cells in the endometrium of women with gynaecological pathologies. Laboratory Professor Dharani Hapangama
Characterising the cellular composition of different uterine myometrial subregions in women. Laboratory Professor Dharani Hapangama
Mechanisms of sperm choice in female insects. Laboratory Dr Liam Dougherty
Supramolecular Organisation of Morphogen Signal by Atomic Force Microscope. Laboratory Dr Marisa Merino
Influence of Extracellular Matrix on Induced Pluripotent Stem Cell Differentiation into Corneal Endothelial Cells for Cell Therapy. Laboratory Emine Bilir
Vascular dysfunction related to Heavy Menstrual Bleeding. Laboratory Professor Dharani Hapangama
Genomic mechanisms of RNA surveillance and quality control. Laboratory Dr Manolis Papamichos Chronakis
Oxygen Enhanced (OE) and Dynamic Contrast Enhanced (DCE) Multispectral Optoacoustic Imaging (MSOT) to measure functional changes in a murine tumour model. Laboratory Professor Harish Poptani
Optical and Ultrasound Imaging to monitor treatment response in a murine tumour model. Laboratory Professor Harish Poptani
Correlation of Dynamic contrast Enhance (DCE) Optoacoustic Imaging (OAI) with Magnetic Resonance Imaging (MRI) in an Ischemic Reperfusion Injury murine model. Laboratory Professor Harish Poptani
Multi-modal imaging for assessing tumour hypoxia and treatment response in rodent models. Laboratory Professor Harish Poptani
Assessing cancer metabolism and microenvironment in in ovo. Laboratory Professor Harish Poptani
Dynamic contrast-enhanced MRI to assess treatment response in brain tumours. Laboratory Professor Harish Poptani

 

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