Dr Pradeep Harish PhD

Postdoctoral Research Associate Pharmacology & Therapeutics

Work email Pradeep.Harish@liverpool.ac.uk
Personal Websitehttps://www.linkedin.com/in/drpradeepharish/

Publications

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2023

Novel Metabolomic Approach for Identifying Pathology-Specific Biomarkers in Rare Diseases: A Case Study in Oculopharyngeal Muscular Dystrophy (OPMD) (Journal article)

Harish, P., Malerba, A., Kroon, R. H. M. J. M., Shademan, M., van Engelan, B., Raz, V., . . . Snowden, S. G. G. (2023). Novel Metabolomic Approach for Identifying Pathology-Specific Biomarkers in Rare Diseases: A Case Study in Oculopharyngeal Muscular Dystrophy (OPMD). METABOLITES, 13(6). doi:10.3390/metabo13060769

DOI: 10.3390/metabo13060769

Systemic Delivery of a Monoclonal Antibody to Immunologically Block Myostatin in the A17 Mouse Model of OPMD. (Chapter)

Malerba, A., Harish, P., & Popplewell, L. (2023). Systemic Delivery of a Monoclonal Antibody to Immunologically Block Myostatin in the A17 Mouse Model of OPMD.. In Unknown Book (Vol. 2587, pp. 557-568). doi:10.1007/978-1-0716-2772-3_30

DOI: 10.1007/978-1-0716-2772-3_30

2021

Knockdown of Muscle-Specific Ribosomal Protein L3-Like Enhances Muscle Function in Healthy and Dystrophic Mice (Journal article)

Kao, B. R., Malerba, A., Lu-Nguyen, N. B., Harish, P., McCarthy, J. J., Dickson, G., & Popplewell, L. J. (2021). Knockdown of Muscle-Specific Ribosomal Protein L3-Like Enhances Muscle Function in Healthy and Dystrophic Mice. NUCLEIC ACID THERAPEUTICS, 31(6), 457-464. doi:10.1089/nat.2020.0928

DOI: 10.1089/nat.2020.0928

2020

Age-Associated Salivary MicroRNA Biomarkers for Oculopharyngeal Muscular Dystrophy (Journal article)

Raz, V., Kroon, R. H. M. J. M., Mei, H., Riaz, M., Buermans, H., Lassche, S., . . . van Engelen, B. G. M. (2020). Age-Associated Salivary MicroRNA Biomarkers for Oculopharyngeal Muscular Dystrophy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(17). doi:10.3390/ijms21176059

DOI: 10.3390/ijms21176059

Fast Facts: Gene Therapy (Journal article)

Herzog, R., & Popplewell, L. (2020). Fast Facts: Gene Therapy. doi:10.1159/isbn.978-3-318-06667-8

DOI: 10.1159/isbn.978-3-318-06667-8

Inhibition of Myostatin Reduces Collagen Deposition in a Mouse Model of Oculopharyngeal Muscular Dystrophy (OPMD) With Established Disease (Journal article)

Harish, P., Forrest, L., Herath, S., Dickson, G., Malerba, A., & Popplewell, L. (2020). Inhibition of Myostatin Reduces Collagen Deposition in a Mouse Model of Oculopharyngeal Muscular Dystrophy (OPMD) With Established Disease. FRONTIERS IN PHYSIOLOGY, 11. doi:10.3389/fphys.2020.00184

DOI: 10.3389/fphys.2020.00184

2019

Inhibition of myostatin improves muscle atrophy in oculopharyngeal muscular dystrophy (OPMD) (Journal article)

Harish, P., Malerba, A., Ngoc, L. -N., Forrest, L., Cappellari, O., Roth, F., . . . Dickson, G. (2019). Inhibition of myostatin improves muscle atrophy in oculopharyngeal muscular dystrophy (OPMD). JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 10(5), 1016-1026. doi:10.1002/jcsm.12438

DOI: 10.1002/jcsm.12438

A pilot study to elucidate effects of artificial selection by size on the zebrafish (<i>Danio rerio</i>) fast skeletal muscle transcriptome (Journal article)

Harish, P., Mareco, E. A., & de la Serrana, G. D. (2019). A pilot study to elucidate effects of artificial selection by size on the zebrafish (<i>Danio rerio</i>) fast skeletal muscle transcriptome. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 233, 65-73. doi:10.1016/j.cbpa.2019.03.021

DOI: 10.1016/j.cbpa.2019.03.021

Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy (Journal article)

Malerba, A., Roth, F., Harish, P., Dhiab, J., Ngoc, L. -N., Cappellari, O., . . . Trollet, C. (2019). Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy. HUMAN MOLECULAR GENETICS, 28(10), 1694-1708. doi:10.1093/hmg/ddz007

DOI: 10.1093/hmg/ddz007

Gene Therapy for Oculopharyngeal Muscular Dystrophy (Chapter)

Malerba, A., Roth, F., Strings, V., Harish, P., Suhy, D., Trollet, C., & Dickson, G. (2019). Gene Therapy for Oculopharyngeal Muscular Dystrophy. In Muscle Gene Therapy (pp. 549-564). Springer International Publishing. doi:10.1007/978-3-030-03095-7_31

DOI: 10.1007/978-3-030-03095-7_31

2018

Advances in emerging therapeutics for oculopharyngeal muscular dystrophy (Journal article)

Harish, P., Dickson, G., & Malerba, A. (2018). Advances in emerging therapeutics for oculopharyngeal muscular dystrophy. EXPERT OPINION ON ORPHAN DRUGS, 6(11), 693-701. doi:10.1080/21678707.2018.1536542

DOI: 10.1080/21678707.2018.1536542

2017

Nuclear PABPN1 aggregates in OPMD: correlation study and therapy (Journal article)

Roth, F., Jarmin, S., Oliver, A., Nguyen, N., Chappell, A., Harish, P., . . . Trollet, C. (2017). Nuclear PABPN1 aggregates in OPMD: correlation study and therapy. NEUROMUSCULAR DISORDERS, 27, S202-S203. doi:10.1016/j.nmd.2017.06.394

DOI: 10.1016/j.nmd.2017.06.394

2015

Progress on Gene Therapy, Cell Therapy, and Pharmacological Strategies Toward the Treatment of Oculopharyngeal Muscular Dystrophy (Journal article)

Harish, P., Malerba, A., Dickson, G., & Bachtarzi, H. (2015). Progress on Gene Therapy, Cell Therapy, and Pharmacological Strategies Toward the Treatment of Oculopharyngeal Muscular Dystrophy. HUMAN GENE THERAPY, 26(5), 286-292. doi:10.1089/hum.2015.014

DOI: 10.1089/hum.2015.014