2022
Mellone, M., Piotrowska, K., Venturi, G., James, L., Bzura, A., Lopez, M. A., . . . Thomas, G. J. (2022). ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance. CANCER RESEARCH, 82(24), 4571-4585. doi:10.1158/0008-5472.CAN-22-0435DOI: 10.1158/0008-5472.CAN-22-0435
Gan, C. P., Lee, B. K. B., Lau, S. H., Kallarakkal, T. G., Zaini, Z. M., Lye, B. K. W., . . . Lim, K. P. (2022). Transcriptional analysis highlights three distinct immune profiles of high-risk oral epithelial dysplasia. FRONTIERS IN IMMUNOLOGY, 13. doi:10.3389/fimmu.2022.954567DOI: 10.3389/fimmu.2022.954567
Meleshko, A., Piatrouskaya, N., Vashkevich, K., Lutskovich, D., Wang, C., Dormeshkin, D., . . . Katsin, M. (2022). Safety and Immunogenicity of Combined DNA-Polyethylenimine and Oral Bacterial Idiotypic Vaccine for Patients with B-Cell Non-Hodgkin Lymphoma: A Pilot Study. CANCERS, 14(14). doi:10.3390/cancers14143298DOI: 10.3390/cancers14143298
McCann, K., von Witzleben, A., Thomas, J., Wang, C., Wood, O., Singh, D., . . . Ottensmeier, C. (2022). Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer.. Journal for immunotherapy of cancer, 10(3). doi:10.1136/jitc-2021-003821DOI: 10.1136/jitc-2021-003821
2021
IMMUNE PROFILING REVEALS ENRICHMENT OF DISTINCT IMMUNE SIGNATURES IN HIGH-RISK ORAL POTENTIALLY MALIGNANT DISORDERS (Conference Paper)
Gan, C., Lee, B. K. B., Lau, S. H., Kallarakkal, T. G., Zaini, Z. M., Zain, R. B., . . . Lim, K. P. (2021). IMMUNE PROFILING REVEALS ENRICHMENT OF DISTINCT IMMUNE SIGNATURES IN HIGH-RISK ORAL POTENTIALLY MALIGNANT DISORDERS. In JOURNAL FOR IMMUNOTHERAPY OF CANCER Vol. 9 (pp. A957). doi:10.1136/jitc-2021-SITC2021.911DOI: 10.1136/jitc-2021-SITC2021.911
Wang, C., Zainal, N. S., Chai, S. J., Dickie, J., Gan, C. P., Zulaziz, N., . . . Lim, K. P. (2021). DNA Vaccines Targeting Novel Cancer-Associated Antigens Frequently Expressed in Head and Neck Cancer Enhance the Efficacy of Checkpoint Inhibitor. FRONTIERS IN IMMUNOLOGY, 12. doi:10.3389/fimmu.2021.763086DOI: 10.3389/fimmu.2021.763086
2020
Savelyeva, N., & Ottensmeier, C. H. (2020). Novel players: tissue-resident memory B cells. BLOOD, 136(24), 2722-2723. doi:10.1182/blood.2020007890DOI: 10.1182/blood.2020007890
von Witzleben, A., Wang, C., Laban, S., Savelyeva, N., & Ottensmeier, C. H. (2020). HNSCC: Tumour Antigens and Their Targeting by Immunotherapy. CELLS, 9(9). doi:10.3390/cells9092103DOI: 10.3390/cells9092103
Ford, K., Hanley, C. J., Mellone, M., Szyndralewiez, C., Heitz, F., Wiesel, P., . . . Thomas, G. J. (2020). NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors. CANCER RESEARCH, 80(9), 1846-1860. doi:10.1158/0008-5472.CAN-19-3158DOI: 10.1158/0008-5472.CAN-19-3158
2019
Combination immunotherapy successfully control tumor growth in a transgenic mouse model (Conference Paper)
Lim, K. P., Zainal, S., Zulaziz, N., Gan, C. P., Chai, S. J., Lye, B. K. W., . . . Cheong, S. C. (2019). Combination immunotherapy successfully control tumor growth in a transgenic mouse model. In CANCER RESEARCH Vol. 79. doi:10.1158/1538-7445.AM2019-1466DOI: 10.1158/1538-7445.AM2019-1466
Plant viral particle vaccine induces a potent antitumor response through induction of antigen-specific T-cells and overcoming an immunosuppressive tumor microenvironment (Conference Paper)
Wang, C., Wang, Y., Allen, A. J., Jobsri, J., Thomas, G. J., Ottensmeier, C. H., & Savelyeva, N. (2019). Plant viral particle vaccine induces a potent antitumor response through induction of antigen-specific T-cells and overcoming an immunosuppressive tumor microenvironment. In CANCER IMMUNOLOGY RESEARCH Vol. 7. doi:10.1158/2326-6074.CRICIMTEATIAACR18-B139DOI: 10.1158/2326-6074.CRICIMTEATIAACR18-B139
2018
Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model (Journal article)
Allen, A., Wang, C., Caproni, L. J., Sugiyarto, G., Harden, E., Douglas, L. R., . . . Savelyeva, N. (2018). Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model. CANCER IMMUNOLOGY IMMUNOTHERAPY, 67(4), 627-638. doi:10.1007/s00262-017-2111-yDOI: 10.1007/s00262-017-2111-y
2017
Cancer Vaccines Preface (Chapter)
Savelyeva, N., & Ottensmeier, C. (2017). Cancer Vaccines Preface. In CANCER VACCINES (Vol. 405, pp. V-VI). Retrieved from https://www.webofscience.com/
Linked CD4 T Cell Help: Broadening Immune Attack Against Cancer by Vaccination (Journal article)
Savelyeva, N., Allen, A., Chotprakaikiat, W., Harden, E., Jobsri, J., Godeseth, R., . . . Ottensmeier, C. (2017). Linked CD4 T Cell Help: Broadening Immune Attack Against Cancer by Vaccination. CANCER VACCINES, 405, 123-143. doi:10.1007/82_2016_500DOI: 10.1007/82_2016_500
2016
Wood, O., Woo, J., Seumois, G., Savelyeva, N., McCann, K. J., Singh, D., . . . Consortium, S. P. A. R. C. (2016). Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors. Oncotarget, 7(35), 56781-56797. doi:10.18632/oncotarget.10788DOI: 10.18632/oncotarget.10788
A plant-expressed conjugate vaccine breaks CD4<SUP>+</SUP> tolerance and induces potent immunity against metastatic Her2<SUP>+</SUP> breast cancer (Journal article)
Chotprakaikiat, W., Allen, A., Bui-Minh, D., Harden, E., Jobsri, J., Cavallo, F., . . . Savelyeva, N. (2016). A plant-expressed conjugate vaccine breaks CD4<SUP>+</SUP> tolerance and induces potent immunity against metastatic Her2<SUP>+</SUP> breast cancer. ONCOIMMUNOLOGY, 5(6). doi:10.1080/2162402X.2016.1166323DOI: 10.1080/2162402X.2016.1166323
2015
Plant Virus Particles Carrying Tumour Antigen Activate TLR7 and Induce High Levels of Protective Antibody (Journal article)
Jobsri, J., Allen, A., Rajagopal, D., Shipton, M., Kanyuka, K., Lomonossoff, G. P., . . . Savelyeva, N. (2015). Plant Virus Particles Carrying Tumour Antigen Activate TLR7 and Induce High Levels of Protective Antibody. PLOS ONE, 10(2). doi:10.1371/journal.pone.0118096DOI: 10.1371/journal.pone.0118096
2013
Genetic Vaccines against Cancer (Chapter)
Stevenson, F. K., di Genova, G., Ottensmeier, C. H., & Savelyeva, N. (2013). Genetic Vaccines against Cancer. In Cancer Immunotherapy (pp. 223-239). Elsevier. doi:10.1016/b978-0-12-394296-8.00015-4DOI: 10.1016/b978-0-12-394296-8.00015-4
2007
Cancer Vaccines (Chapter)
Stevenson, F. K., Genova, G. D., Ottensmeier, C., & Savelyeva, N. (2007). Cancer Vaccines. In Cancer Immunotherapy (pp. 183-204). Elsevier. doi:10.1016/b978-012372551-6/50075-4DOI: 10.1016/b978-012372551-6/50075-4
2004
DNA vaccines to attack cancer (Journal article)
Stevenson, F. K., Ottensmeier, C. H., Johnson, P., Zhu, D. L., Buchan, S. L., McCann, K. J., . . . Rice, J. (2004). DNA vaccines to attack cancer. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101, 14646-14652. doi:10.1073/pnas.0404896101DOI: 10.1073/pnas.0404896101