Mass spectrometry

In mass spectrometry, we currently perform:

  • LC-MS where we focus on reversed phase for the analysis of lipophilic species; this is performed on our Thermo Scientific Q Exactive, Orbitrap ID-X Tribrid and Orbitrap Exploris 240 or Agilent ion mobility MS system, for untargeted metabolite analysis
  • LC-triple quadrupole systems from Thermo Scientifc, Agilent and SCIEX which are dedicated for the quantification of target metabolites
  • An acoustic ejection based interface from SCIEX (Echo MS) linked to a triple quadrupole for high throughput targeted analyses
  • For the analysis of polar non-volatile metabolites we apply GC-MS using Agilent GC-Q-ToF and Leco Pegasus BT GC x GC-ToF MS incorporating just in time derisatization (methoximation and silylation)
  • For the analysis of volatile organic compounds (VOCs) an Agilent GC-Q-ToF MS system with Markes Thermal Desorption is applied.

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