Centre for Genomic Research

The Centre for Genomic Research (CGR) offers state-of-the-art, multi-platform sequencing technologies to enhance genomics research.

Photograph of a researcher wearing a lab coat and gloves, holding a piece of equipment

The Centre’s next generation equipment and resources are supported by experienced and knowledgeable technical specialists and renowned academics to help you acquire the data you need.

Click here to access the full Centre for Genomic Research website.

What you'll receive from our facility

We have an international reputation for academic research and industry collaboration, undertaking a broad range of cutting-edge projects across areas as diverse as biotechnology, food security, medical research, metagenomics and zoology
Our facility staff are available to share their expertise, working tirelessly to ensure you obtain results of the highest possible quality, starting from project design and extending through sample preparation, sequencing and data analysis
We offer training in data analysis via the NERC Environmental Omics Facility (NEOF)
We are committed to sustainability and have been certified Silver under the Laboratory Efficiency Assessment Framework (LEAF).

Our equipment and capability includes:

Illumina NovaSeq X Plus
Pacbio Sequel IIe
10x Genomics Chromium and Chromium X
Sample QC using the Bioanalyzer, Fragment analyzer and FEMTOPulse, Qubit, Nanodrop
Library preparation for a wide range of applications
Automated sample and library preparation using the Formulatrix FAST, SPT Labtech Mosquito and OpenTron OT-2 platforms.

Who can use our facilities

University of Liverpool academic staff
Researchers from other universities/ research institutions
Industrial research partners.

What Genomic Research can be used for

Any applications requiring large amounts of high-quality whole genome sequencing data
Microbial taxonomic assignment and functional profiling, such as metagenomics, metatranscriptomics and metabarcoding applications
RNA sequencing applications, including differential gene expression and differential transcript usage analyses
Long-read sequencing applications, such as de novo genome assembly, detection of structural variants, resolution of repetitive genomic regions, IsoSeq and assembly of metagenome-assembled genomes (MAGs)
Single cell transcriptomics, T- and B-cell profiling and ATAC-seq
Bespoke bioinformatics support.

chemistry

Booking our facilities

The best way to contact us is through our enquiry form, but you can also email us directly at CGR.Enquiries@liverpool.ac.uk or call 0151 795 8303.

Equipment

Short-read sequencing

Using Illumina's market-leading sequencing-by-synthesis (SBS) technology, we can keep costs down while producing publication quality data. We use both high and low output platforms to meet the needs of projects of all sizes.

Long-read sequencing

The single-molecule real-time (SMRT) long read sequencing technology developed by PacBio produces the highest quality sequencing data. Long-reads significantly improve the performance of many downstream applications.

Single-cell sequencing

High-resolution analysis of biological material is made possible by microfluidic separation of individual cells or nuclei. We offer transcriptomics, immunological profiling and ATAC seq with the 10x Genomics Chromium platforms.

Library preparation

We generate sequencing libraries tried and tested techniques, tools and materials. Our seasoned and highly-trained sequence production team works industriously to deliver the best outcomes in the shortest possible time.

Quality control

We evaluate the quality of all samples received and advise collaborators on any issues before proceeding with further work. This enables us to avoid sample drop out and ensures the best possible results.

Other laboratory services

In order to maximise the performance of samples in subsequent applications, we provide services to enhance the quality of submitted samples that do not meet our specified requirements.

Data analysis

Our expert bioinformaticians and statisticians use the latest tools and methods to deliver professional data integration and analysis, clear reports and publication quality figures.

Automation

We use an array of tried-and-true automated liquid handling platforms to drive costs down and accelerate project turnaround. Our team strive to implement effective and efficient automation of widely used sample preparation protocols.