Publications
2024
The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk.
McDonnell, E., Orr, S. E., Barter, M. J., Rux, D., Brumwell, A., Wrobel, N., . . . Rice, S. J. (2024). The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk.. American journal of human genetics, 111(12), 2756-2772. doi:10.1016/j.ajhg.2024.10.017
SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesis.
Barter, M. J., Turner, D. A., Rice, S. J., Hines, M., Lin, H., Falconer, A. M. D., . . . Wilkinson, D. J. (2024). SERPINA3 is a marker of cartilage differentiation and is essential for the expression of extracellular matrix genes during early chondrogenesis.. Matrix biology : journal of the International Society for Matrix Biology, S0945-053X(24)00095-7. doi:10.1016/j.matbio.2024.07.004
Epigenetic mechanisms of osteoarthritis risk in human skeletal development.
Epigenomic landscape across human articular cartilage development
McDonnell, E., Brumwell, A., Wrobel, N., Murphy, L., Overmann, L. M., Lisgo, S. N., . . . Rice, S. J. (2024). Epigenomic landscape across human articular cartilage development. Osteoarthritis and Cartilage, 32, S14-S15. doi:10.1016/j.joca.2024.02.023
SERPINA3 (ALPHA-1 ANTICHYMOTRYPSIN) IS ESSENTIAL FOR EXTRACELLULAR MATRIX PRODUCTION DURING CARTILAGE FORMATION AND REGULATES THE CHONDROGENIC TRANSCRIPTION FACTOR SOX9
Barter, M. J., Turner, D. A., Rice, S. J., Hines, M., Lin, H., Falconer, A. M., . . . WILKINSON, D. J. (2024). SERPINA3 (ALPHA-1 ANTICHYMOTRYPSIN) IS ESSENTIAL FOR EXTRACELLULAR MATRIX PRODUCTION DURING CARTILAGE FORMATION AND REGULATES THE CHONDROGENIC TRANSCRIPTION FACTOR SOX9. Osteoarthritis and Cartilage, 32, S389. doi:10.1016/j.joca.2024.02.568
2023
Custom Workflow for the Confident Identification of Sulfotyrosine-Containing Peptides and Their Discrimination from Phosphopeptides.
Daly, L. A., Byrne, D. P., Perkins, S., Brownridge, P. J., McDonnell, E., Jones, A. R., . . . Eyers, C. E. (2023). Custom Workflow for the Confident Identification of Sulfotyrosine-Containing Peptides and Their Discrimination from Phosphopeptides.. Journal of proteome research, 22(12), 3754-3772. doi:10.1021/acs.jproteome.3c00425
Extensible benchmarking of methods that identify and quantify polyadenylation sites from RNA-seq data.
Bryce-Smith, S., Burri, D., Gazzara, M. R., Herrmann, C. J., Danecka, W., Fitzsimmons, C. M., . . . Zavolan, M. (2023). Extensible benchmarking of methods that identify and quantify polyadenylation sites from RNA-seq data.. RNA (New York, N.Y.), 29(12), 1839-1855. doi:10.1261/rna.079849.123
2022
Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication.
Harper, K. L., Mottram, T. J., Anene, C. A., Foster, B., Patterson, M. R., McDonnell, E., . . . Whitehouse, A. (2022). Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication.. EMBO reports, 23(5), e54117. doi:10.15252/embr.202154117
2019
CircRNAs: From anonymity to novel regulators of gene expression in cancer (Review).
Harper, K. L., Mcdonnell, E., & Whitehouse, A. (2019). CircRNAs: From anonymity to novel regulators of gene expression in cancer (Review).. International journal of oncology, 55(6), 1183-1193. doi:10.3892/ijo.2019.4904