First peer-reviewed paper publication of Johannes Petzoldt within OMA project

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Johannes Petzoldt, OMA Fellow from IBA, is happy to announce his first peer-reviewed paper publication within the OMA project. He co-authored the sensitivity study of the prompt-gamma (PG) camera of IBA, which has been published by Lena Nenoff et al., Johannes’ collaboration partners at OncoRay in Dresden, Germany. The paper is being published in a special issue of “Radiotherapy & Oncology”, one of the most prestigious journals in radiation therapy.

Detected range shifts between measurement and simulation for separate spots in 6 consecutive energy layers of the IMPT 1Gy field. Spot size correlates with the number of protons. For each layer, the layer-averaged shifts ± standard deviations are given. For local shifts (black circle), this is done separately in- and outside of the affected area. Source: ‘Sensitivity of a prompt-gamma slit-camera to detect range shifts for proton treatment verification’, Lena Nenoff et al., Radiotherapy and Oncology, Article in press.

Lena Nenoff et al. investigated the limitations of the PG slit camera, delivering clinical treatment plans on an anthropomorphic phantom. During the experiments, local and global range variations of different magnitude were introduced and the ability of the PG camera to detect those range shifts was challenged and further investigated. Johannes contributed mostly with a calibration measurement of the PG camera, which he performed in December 2016 in his first secondment at OncoRay. Based on his results, the PG simulation accuracy could be highly improved and the robustness of the data analysis was increased. The results of the study further strengthen the confidence in range verification measurements using the PG camera. 

 

Full article:

‘Sensitivity of a prompt-gamma slit-camera to detect range shifts for proton treatment verification’, Lena Nenoff, Marlen Priegnitz, Guillaume Janssens, Johannes Petzoldt, Patrick Wohlfahrt, Anna Trezza, Julien Smeets, Guntram Pausch, Christian Richter, Radiotherapy and Oncology, Article in press, DOI: http://dx.doi.org/10.1016/j.radonc.2017.10.013