Dr Rosemary Maher PhD

Personal Statement

Rosie graduated with a BSc in Biomedical Science from the University of Sheffield in 2016 and has recently received her PhD from the University of Liverpool in 2022. During her PhD, Rosie used mass spectrometry-based proteomic methods to assess respiratory disease and pulmonary aspiration in adults with cystic fibrosis, children severe neurodisability and in dogs, idiopathic pulmonary fibrosis. The overall goal of Rosie’s PhD was to provide an understanding of the molecular mechanisms that underpin respiratory disease in these clinical cohorts by highlighting proteins and protein pathways involved in disease pathogenesis and lung function decline. Rosie now holds a postdoctoral position within the Centre for Proteome Research (Emmott Lab) continuing her research into cystic fibrosis lung disease, specifically investigating elexacaftor–tezacaftor–ivacaftor, a novel CFTR modulator treatment that produces dramatic clinical improvements in cystic fibrosis patients, and its effect on the sputum and plasma proteome