Dr Roz Jenkins BSc (Hons), PhD
Principal Research Technical Professional and Lab Manager, CDSS Bioanalytical Facility Pharmacology & Therapeutics
- +44 (0)151 794 8214
- Work email R.Jenkins@liverpool.ac.uk
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2024
Amyloid-Fibrinogen Aggregates ("Microclots") Predict Risks of Disseminated Intravascular Coagulation and Mortality. (Journal article)
Schofield, J., Abrams, S. T., Jenkins, R., Lane, S., Wang, G., & Toh, C. -H. (2024). Amyloid-Fibrinogen Aggregates ("Microclots") Predict Risks of Disseminated Intravascular Coagulation and Mortality.. Blood advances, bloodadvances.2023012473. doi:10.1182/bloodadvances.2023012473Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory 'multi-omics' study to identify composite biomarkers. (Journal article)
Clarke, E., Varela, L., Jenkins, R. E., Lozano-Andrés, E., Cywińska, A., Przewozny, M., . . . Wauben, M. H. M. (2024). Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory 'multi-omics' study to identify composite biomarkers.. Biochemistry and biophysics reports, 37, 101635. doi:10.1016/j.bbrep.2023.1016352023
A systems approach reveals species differences in hepatic stress response capacity (Journal article)
Russomanno, G., Sison-Young, R., Livoti, L. A., Coghlan, H., Jenkins, R. E., Kunnen, S. J., . . . Copple, I. M. (2023). A systems approach reveals species differences in hepatic stress response capacity. TOXICOLOGICAL SCIENCES. doi:10.1093/toxsci/kfad085Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis. (Journal article)
Anderson, J. R., Johnson, E., Jenkins, R., Jacobsen, S., Green, D., Walters, M., . . . Peffers, M. J. (2023). Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis.. International journal of molecular sciences, 24(19), 14888. doi:10.3390/ijms241914888Ras protein abundance correlates with Ras isoform mutation patterns in cancer (Journal article)
Hood, F. E., Sahraoui, Y. M., Jenkins, R. E., & Prior, I. A. (2023). Ras protein abundance correlates with Ras isoform mutation patterns in cancer. ONCOGENE, 42(15), 1224-1232. doi:10.1038/s41388-023-02638-12022
Temporal extracellular vesicle protein changes following intraarticular treatment with integrin α10β1-selected mesenchymal stem cells in equine osteoarthritis. (Journal article)
Clarke, E. J., Johnson, E., Caamaño Gutierrez, E., Andersen, C., Berg, L. C., Jenkins, R. E., . . . Peffers, M. J. (2022). Temporal extracellular vesicle protein changes following intraarticular treatment with integrin α10β1-selected mesenchymal stem cells in equine osteoarthritis.. Frontiers in veterinary science, 9, 1057667. doi:10.3389/fvets.2022.10576672021
Glycation of Host Proteins Increases Pathogenic Potential of <i>Porphyromonas gingivalis</i> (Journal article)
Smiga, M., Smalley, J. W., Slezak, P., Brown, J. L., Sieminska, K., Jenkins, R. E., . . . Olczak, T. (2021). Glycation of Host Proteins Increases Pathogenic Potential of <i>Porphyromonas gingivalis</i>. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(21). doi:10.3390/ijms222112084The application of cytokeratin-18 as a biomarker for drug-induced liver injury (Journal article)
Korver, S., Bowen, J., Pearson, K., Gonzalez, R. J., French, N., Park, K., . . . Goldring, C. (2021). The application of cytokeratin-18 as a biomarker for drug-induced liver injury. ARCHIVES OF TOXICOLOGY, 95(11), 3435-3448. doi:10.1007/s00204-021-03121-0Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification (Journal article)
Howell, L., Jenkins, R. E., Lynch, S., Duckworth, C., Kevin Park, B., & Goldring, C. (2021). Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification. ARCHIVES OF TOXICOLOGY, 95(7), 2413-2430. doi:10.1007/s00204-021-03075-3Absolute Quantitation of GTPase Protein Abundance (Journal article)
Hood, F. E., Sahraoui, Y. M., Jenkins, R. E., & Prior, I. (2021). Absolute Quantitation of GTPase Protein Abundance. RAS ACTIVITY AND SIGNALING, 2262, 65-90. doi:10.1007/978-1-0716-1190-6_4The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells (Journal article)
Ide, K., Takahashi, S., Sakai, K., Taga, Y., Ueno, T., Dickens, D., . . . Sakai, T. (2021). The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells. Journal of Biological Chemistry, 100819. doi:10.1016/j.jbc.2021.100819Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells. (Journal article)
Eagle, G. L., Herbert, J. M. J., Zhuang, J., Oates, M., Khan, U. T., Kitteringham, N. R., . . . Falciani, F. (2021). Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells.. Scientific Reports, 11(1), 2932. doi:10.1038/s41598-021-82609-22020
Characterization of Clozapine-Responsive Human T Cells (Journal article)
Ogese, M. O., Lister, A., Jenkins, R. E., Meng, X., Alfirevic, A., Douglas, L., . . . Naisbitt, D. J. (2020). Characterization of Clozapine-Responsive Human T Cells. JOURNAL OF IMMUNOLOGY, 205(9), 2375-+. doi:10.4049/jimmunol.2000646Identification of Flucloxacillin-Haptenated HLA-B*57:01 Ligands: Evidence of Antigen Processing and Presentation (Journal article)
Waddington, J. C., Meng, X., Illing, P. T., Tailor, A., Adair, K., Whitaker, P., . . . Park, B. K. (2020). Identification of Flucloxacillin-Haptenated HLA-B*57:01 Ligands: Evidence of Antigen Processing and Presentation. TOXICOLOGICAL SCIENCES, 177(2), 454-465. doi:10.1093/toxsci/kfaa124The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine. (Journal article)
Jolly, C. E., Douglas, O., Kamalian, L., Jenkins, R. E., Beckett, A. J., Penman, S. L., . . . Chadwick, A. E. (2020). The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine.. Toxicology and applied pharmacology, 403, 115163. doi:10.1016/j.taap.2020.1151632019
Exosomal transport of hepatocyte-derived drug-modified proteins to the immune system. (Journal article)
Ogese, M. O., Jenkins, R. E., Adair, K., Tailor, A., Meng, X., Faulkner, L. L., . . . Betts, C. (2019). Exosomal transport of hepatocyte-derived drug-modified proteins to the immune system.. Hepatology, 70(5), 1732-1749. doi:10.1002/hep.30701Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells (Journal article)
Austin, J. A., Jenkins, R. E., Austin, G. M., Glenn, M. A., Dunn, K., Scott, L., . . . Clark, R. E. (2019). Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells. BIOCHEMICAL JOURNAL, 476, 2255-2269. doi:10.1042/BCJ201901212018
Proteomic profiling of rectal cancer reveals acid ceramidase is implicated in radiation response (Journal article)
Bowden, D. L., Sutton, P. A., Wall, M. A., Jithesh, P. V., Jenkins, R. E., Palmer, D. H., . . . Vimalachandran, D. (2018). Proteomic profiling of rectal cancer reveals acid ceramidase is implicated in radiation response. JOURNAL OF PROTEOMICS, 179, 53-60. doi:10.1016/j.jprot.2018.02.030In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A) (Conference Paper)
Austin, J. A., Lucas, C. M., Jenkins, R. E., Dunn, K., Scott, L. J., Glenn, M. A., . . . Clark, R. E. (2018). In chronic myeloid leukaemia cells, the oncoprotein CIP2A binds directly to and alters expression of many cellular proteins, independent of effects on protein phosphatase 2A (PP2A). In BRITISH JOURNAL OF HAEMATOLOGY Vol. 181 (pp. 52-53). Retrieved from https://www.webofscience.com/Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study (Journal article)
Bell, C. C., Dankers, A. C. A., Lauschke, V. M., Sison-Young, R., Jenkins, R., Rowe, C., . . . Ingelman-Sundberg, M. (2018). Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study. TOXICOLOGICAL SCIENCES, 162(2), 655-666. doi:10.1093/toxsci/kfx2892017
Assessment of Antipiperacillin IgG Binding to Structurally Related Drug Protein Adducts (Journal article)
Amali, M. O., Jenkins, R. E., Meng, X., Faulkner, L., Whitaker, P., Peckham, D., . . . Naisbitt, D. J. (2017). Assessment of Antipiperacillin IgG Binding to Structurally Related Drug Protein Adducts. CHEMICAL RESEARCH IN TOXICOLOGY, 30(12), 2097-2099. doi:10.1021/acs.chemrestox.7b00291Ethanol Stimulates Locomotion via a G(alpha s)-Signaling Pathway in IL2 Neurons in Caenorhabditis elegans (Journal article)
Johnson, J. R., Edwards, M. R., Davies, H., Newman, D., Holden, W., Jenkins, R. E., . . . Barclay, J. W. (2017). Ethanol Stimulates Locomotion via a G(alpha s)-Signaling Pathway in IL2 Neurons in Caenorhabditis elegans. GENETICS, 207(3), 1023-1039. doi:10.1534/genetics.117.300119Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from Epoxide Metabolites of Carbamazepine in Patients (Journal article)
Yip, V. L. M., Meng, X., Maggs, J. L., Jenkins, R., Marlot, P., Marson, A., . . . Pirmohamed, M. (2017). Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from Epoxide Metabolites of Carbamazepine in Patients. Chemical Research in Toxicology, 30(7), 1419-1435. doi:10.1021/acs.chemrestox.7b00063Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells (Journal article)
Ogese, M. O., Faulkner, L., Jenkins, R. E., French, N. S., Copple, I. M., Antoine, D. J., . . . Naisbitt, D. J. (2017). Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells. TOXICOLOGICAL SCIENCES, 158(1), 76-89. doi:10.1093/toxsci/kfx069Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients. (Journal article)
Meng, X., Al-Attar, Z., Yaseen, F. S., Jenkins, R., Earnshaw, C., Whitaker, P., . . . Park, B. K. (2017). Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients.. Journal of Immunology, 198(11), 4217-4227. doi:10.4049/jimmunol.1700209Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways (Journal article)
Brandi, J., Dando, I., Dalla Pozza, E., Biondani, G., Jenkins, R., Elliott, V., . . . Palmieri, M. (2017). Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways. JOURNAL OF PROTEOMICS, 150, 310-322. doi:10.1016/j.jprot.2016.10.002Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile (Journal article)
Heslop, J. A., Rowe, C., Walsh, J., Sison-Young, R., Jenkins, R., Kamalian, L., . . . Kevin Park, B. (2017). Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile. Archives of Toxicology, 91(1), 439-452. doi:10.1007/s00204-016-1694-y2016
Amoxicillin and Clavulanate Form Chemically and Immunologically Distinct Multiple Haptenic Structures in Patients (Journal article)
Meng, X., Earnshaw, C. J., Tailor, A., Jenkins, R. E., Waddington, J. C., Whitaker, P., . . . Park, B. K. (2016). Amoxicillin and Clavulanate Form Chemically and Immunologically Distinct Multiple Haptenic Structures in Patients. CHEMICAL RESEARCH IN TOXICOLOGY, 29(10), 1762-1772. doi:10.1021/acs.chemrestox.6b00253Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease (Journal article)
Bell, C. C., Hendriks, D. F. G., Moro, S. M. L., Ellis, E., Walsh, J., Renblom, A., . . . Ingelman-Sundberg, M. (2016). Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease. Scientific Reports, 6. doi:10.1038/srep25187Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus (Journal article)
Jenkinson, C., Elliott, V., Evans, A., Oldfield, L., Jenkins, R., O'Brien, D., . . . Costello-Goldring, E. (2016). Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus. Clinical Cancer Research, 22(7), 1734-1743. doi:10.1158/1078-0432.ccr-15-0879Design and Synthesis of Irreversible Analogues of Bardoxolone Methyl for the Identification of Pharmacologically Relevant Targets and Interaction Sites (Journal article)
Wong, M. H. L., Bryan, H. K., Copple, I. M., Jenkins, R. E., Chiu, P. H., Bibby, J., . . . Park, B. K. (2016). Design and Synthesis of Irreversible Analogues of Bardoxolone Methyl for the Identification of Pharmacologically Relevant Targets and Interaction Sites. JOURNAL OF MEDICINAL CHEMISTRY, 59(6), 2396-2409. doi:10.1021/acs.jmedchem.5b01292Secretome protein signature of human pancreatic cancer stem-like cells (Journal article)
Brandi, J., Dalla Pozza, E., Dando, I., Biondani, G., Robotti, E., Jenkins, R., . . . Cecconi, D. (2016). Secretome protein signature of human pancreatic cancer stem-like cells. JOURNAL OF PROTEOMICS, 136, 1-12. doi:10.1016/j.jprot.2016.01.0172015
Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney (Journal article)
Shelton, L. M., Lister, A., Walsh, J., Jenkins, R. E., Wong, M. H. L., Rowe, C., . . . Copple, I. M. (2015). Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. KIDNEY INTERNATIONAL, 88(06), 1261-1273. doi:10.1038/ki.2015.286Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome (Journal article)
Eakins, R., Walsh, J., Randle, L., Jenkins, R. E., Schuppe-Koistinen, I., Rowe, C., . . . Park, B. K. (2015). Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome. SCIENTIFIC REPORTS, 5. doi:10.1038/srep16423Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication (Journal article)
Sison-Young, R. L. C., Mitsa, D., Jenkins, R. E., Mottram, D., Alexandre, E., Richert, L., . . . Park, B. K. (2015). Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication. TOXICOLOGICAL SCIENCES, 147(2), 412-424. doi:10.1093/toxsci/kfv136Promiscuous T-cell responses to drugs and drug-haptens (Journal article)
Yaseen, F. S., Saide, K., Kim, S. -H., Monshi, M., Tailor, A., Wood, S., . . . Naisbitt, D. J. (2015). Promiscuous T-cell responses to drugs and drug-haptens. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 136(2), 474-+. doi:10.1016/j.jaci.2015.02.036Total Proteome Analysis Identifies Migration Defects as a Major Pathogenetic Factor in Immunoglobulin Heavy Chain Variable Region (IGHV)-unmutated Chronic Lymphocytic Leukemia (Journal article)
Eagle, G., Zhuang, J., Jenkins, R., Till, K., Jithesh, P., Lin, K., . . . Pettitt, A. (2015). Total Proteome Analysis Identifies Migration Defects as a Major Pathogenetic Factor in Immunoglobulin Heavy Chain Variable Region (IGHV)-unmutated Chronic Lymphocytic Leukemia. Molecular and Cellular Proteomics, 14(4), 933-945. doi:10.1074/mcp.M114.044479Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes (Journal article)
Baxter, M., Withey, S., Harrison, S., Segeritz, C. -P., Zhang, F., Atkinson-Dell, R., . . . Hanley, N. A. (2015). Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes. Journal of Hepatology, 62(3), 581-589. doi:10.1016/j.jhep.2014.10.016Characterization of Peroxidases Expressed in Human AntigenPresenting Cells and Analysis of the Covalent Binding of NitrosoSulfamethoxazole to Myeloperoxidase (Journal article)
Ogese, M. O., Jenkins,, R. E., Maggs, J. L., Meng, X., Whitaker, P., Peckham, D., . . . Naisbitt, D. J. (2015). Characterization of Peroxidases Expressed in Human AntigenPresenting Cells and Analysis of the Covalent Binding of NitrosoSulfamethoxazole to Myeloperoxidase. Chemical Research in Toxicology, 28(1), 144-154. doi:10.1021/tx500458k2014
Antigen exposure required for T cell activation (Journal article)
Meng, X., Yaseen, F., Earnshaw, C., Jenkins, R., Peckham, D., Whitaker, P., . . . Park, K. (2014). Antigen exposure required for T cell activation. Clinical and translational allergy, 4(Suppl 3), P115. doi:10.1186/2045-7022-4-s3-p115Characterization of Flucloxacillin-specific CD8+ T-cells in a mouse model (Journal article)
Nattrass, R., Faulkner, L., Jenkins, R., Nicolas, J., Vocanson, M., Rozieres, A., . . . Naisbitt, D. (2014). Characterization of Flucloxacillin-specific CD8+ T-cells in a mouse model. Clinical and translational allergy, 4(Suppl 3), P41. doi:10.1186/2045-7022-4-s3-p41Characterization of anti-drug antibodies and drug-responsive B-lymphocytes in piperacillin hypersensitive patients with cystic fibrosis (Journal article)
Amali, M., Sullivan, A., Farrell, J., Meng, X., Jenkins, R., Whitaker, P., . . . Naisbitt, D. J. (2014). Characterization of anti-drug antibodies and drug-responsive B-lymphocytes in piperacillin hypersensitive patients with cystic fibrosis. Clinical and translational allergy, 4(Suppl 3), P113. doi:10.1186/2045-7022-4-s3-p113Phenotypic analysis of primary colorectal cancer to inform management of metastatic disease (Conference Paper)
Sutton, P., Jones, R., Rowe, C., Jenkins, R., Malik, H., Vimalachandran, D., . . . Kitteringham, N. (2014). Phenotypic analysis of primary colorectal cancer to inform management of metastatic disease. In LANCET Vol. 383 (pp. 98). Retrieved from https://www.webofscience.com/Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl Glucuronide Metabolite: Multiple Albumin Adductions in Diclofenac Patients (Journal article)
Hammond, T. G., Meng, X., Jenkins, R. E., Maggs, J. L., Castelazo, A. S., Regan, S. L., . . . Williams, D. P. (2014). Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl Glucuronide Metabolite: Multiple Albumin Adductions in Diclofenac Patients. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 350(2), 387-402. doi:10.1124/jpet.114.2150792013
Safety pharmacology - Current and emerging concepts (Journal article)
Hamdam, J., Sethu, S., Smith, T., Alfirevic, A., Alhaidari, M., Atkinson, J., . . . Goldring, C. (2013). Safety pharmacology - Current and emerging concepts. TOXICOLOGY AND APPLIED PHARMACOLOGY, 273(2), 229-241. doi:10.1016/j.taap.2013.04.039Proteomic profiling of a mouse model of acute intestinal <i>Apc</i> deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC) (Journal article)
Hammoudi, A., Song, F., Reed, K. R., Jenkins, R. E., Meniel, V. S., Watson, A. J. M., . . . Jenkins, J. R. (2013). Proteomic profiling of a mouse model of acute intestinal <i>Apc</i> deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 440(3), 364-370. doi:10.1016/j.bbrc.2013.08.076Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study (Journal article)
Jones, R. P., Sutton, P., Greensmith, R. M. D., Santoyo-Castelazo, A., Carr, D. F., Jenkins, R., . . . Kitteringham, N. R. (2013). Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 72(2), 359-368. doi:10.1007/s00280-013-2199-5Proteome-wide analyses of human hepatocytes during differentiation and dedifferentiation. (Journal article)
Rowe, C., Gerrard, D. T., Jenkins, R., Berry, A., Durkin, K., Sundstrom, L., . . . Hanley, N. A. (2013). Proteome-wide analyses of human hepatocytes during differentiation and dedifferentiation.. Hepatology (Baltimore, Md.), 58(2), 799-809. doi:10.1002/hep.26414Oxidative Bioactivation of Abacavir in Subcellular Fractions of Human Antigen Presenting Cells (Journal article)
Bell, C. C., Castelazo, A. S., Yang, E. L., Maggs, J. L., Jeankins, R. E., Tugwood, J., . . . Park, B. K. (2013). Oxidative Bioactivation of Abacavir in Subcellular Fractions of Human Antigen Presenting Cells. CHEMICAL RESEARCH IN TOXICOLOGY, 26(7), 1064-1072. doi:10.1021/tx400041vβ-Lactam Antibiotics Form Distinct Haptenic Structures on Albumin and Activate Drug-Specific T-Lymphocyte Responses in Multiallergic Patients with Cystic Fibrosis (Journal article)
Jenkins, R. E., Yaseen, F. S., Monshi, M. M., Whitaker, P., Meng, X., Farrell, J., . . . Naisbitt, D. J. (2013). β-Lactam Antibiotics Form Distinct Haptenic Structures on Albumin and Activate Drug-Specific T-Lymphocyte Responses in Multiallergic Patients with Cystic Fibrosis. CHEMICAL RESEARCH IN TOXICOLOGY, 26(6), 963-975. doi:10.1021/tx400124miTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance (Journal article)
Tonack, S., Jenkinson, C., Cox, T., Elliott, V., Jenkins, R. E., Kitteringham, N. R., . . . Costello, E. (2013). iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance. BRITISH JOURNAL OF CANCER, 108(9), 1846-1853. doi:10.1038/bjc.2013.150iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance (Journal article)
Tonack, S., Jenkinson, C., Cox, T., Elliott, V., Jenkins, R. E., Kitteringham, N. R., . . . Costello, E. (2013). iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance. British Journal of Cancer, 108(9), 1846-1853. doi:10.1038/bjc.2013.150Detection of Drug Bioactivation in Vivo: Mechanism of Nevirapine-Albumin Conjugate Formation in Patients (Journal article)
Meng, X., Howarth, A., Earnshaw, C. J., Jenkins, R. E., French, N. S., Back, D. J., . . . Park, B. K. (2013). Detection of Drug Bioactivation in Vivo: Mechanism of Nevirapine-Albumin Conjugate Formation in Patients. CHEMICAL RESEARCH IN TOXICOLOGY, 26(4), 575-583. doi:10.1021/tx4000107Human Leukocyte Antigen (HLA)-B<SUP>☆</SUP>57:01-Restricted Activation of Drug-Specific T Cells Provides the Immunological Basis for Flucloxacillin-Induced Liver Injury (Journal article)
Monshi, M. M., Faulkner, L., Gibson, A., Jenkins, R. E., Farrell, J., Earnshaw, C. J., . . . Naisbitt, D. J. (2013). Human Leukocyte Antigen (HLA)-B<SUP>☆</SUP>57:01-Restricted Activation of Drug-Specific T Cells Provides the Immunological Basis for Flucloxacillin-Induced Liver Injury. HEPATOLOGY, 57(2), 727-739. doi:10.1002/hep.260772012
Analysis of the rat primary hepatocyte nuclear proteome through sub-cellular fractionation (Journal article)
Goldring, C., Rowe, C., Jenkins, R. E., Kitteringham, N. R., & Park, K. B. (n.d.). Analysis of the rat primary hepatocyte nuclear proteome through sub-cellular fractionation. Journal of Integrated OMICS, 2(2). doi:10.5584/jiomics.v2i2.102Release of TGFβig-h3 by gastric myofibroblasts slows tumor growth and is decreased with cancer progression. (Journal article)
Holmberg, C., Quante, M., Steele, I., Kumar, J. D., Balabanova, S., Duval, C., . . . Varro, A. (2012). Release of TGFβig-h3 by gastric myofibroblasts slows tumor growth and is decreased with cancer progression.. Carcinogenesis, 33(8), 1553-1562. doi:10.1093/carcin/bgs180Characterization of the Antigen Specificity of T-Cell Clones from Piperacillin-Hypersensitive Patients with Cystic Fibrosis (Journal article)
El-Ghaiesh, S., Monshi, M. M., Whitaker, P., Jenkins, R., Meng, X., Farrell, J., . . . Naisbitt, D. J. (2012). Characterization of the Antigen Specificity of T-Cell Clones from Piperacillin-Hypersensitive Patients with Cystic Fibrosis. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 341(3), 597-610. doi:10.1124/jpet.111.190900PKC-2 Phosphorylation of UNC-18 Ser322 in AFD Neurons Regulates Temperature Dependency of Locomotion (Journal article)
Edwards, M. R., Johnson, J. R., Rankin, K., Jenkins, R. E., Maguire, C., Morgan, A., . . . Barclay, J. W. (2012). PKC-2 Phosphorylation of UNC-18 Ser322 in AFD Neurons Regulates Temperature Dependency of Locomotion. JOURNAL OF NEUROSCIENCE, 32(20), 7042-7051. doi:10.1523/JNEUROSCI.4029-11.2012Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics. (Journal article)
Abdullah, A., Kitteringham, N. R., Jenkins, R. E., Goldring, C., Higgins, L., Yamamoto, M., . . . Park, B. K. (2012). Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics.. Pharmacological reports : PR, 64(3), 680-697. doi:10.1016/s1734-1140(12)70863-0HLA-B*57:01-restricted activation of drug-specific T-cells provides the immunological basis for flucloxacillin-induced liver injury (Journal article)
Monshi, M., Faulkner, L., Gibson, A., Jenkins, R. E., Farrell, J., Earnshaw, C. J., . . . Naisbitt, D. J. (2012). HLA-B*57:01-restricted activation of drug-specific T-cells provides the immunological basis for flucloxacillin-induced liver injury. Hepatology.2011
In vitro assessment of the interactions between diclofenac and tolmetin acyl glucuronide drug metabolites and human serum albumin (Journal article)
Hammond, T. G., Regan, S. L., Meng, X., Maggs, J. L., Jenkins, R. E., Kenna, J. G., . . . Park, B. K. (2011). In vitro assessment of the interactions between diclofenac and tolmetin acyl glucuronide drug metabolites and human serum albumin. Toxicology, 290(2-3), 142-143. doi:10.1016/j.tox.2011.09.072Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients (Journal article)
Meng, X., Jenkins, R. E., Berry, N. G., Maggs, J. L., Farrell, J., Lane, C. S., . . . Park, B. K. (2011). Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients. Journal of Pharmacology and Experimental Therapeutics, 338(3), 841-849. doi:10.1124/jpet.111.183871MDM2 interacts with NME2 (non-metastatic cells 2, protein) and suppresses the ability of NME2 to negatively regulate cell motility (Journal article)
Polanski, R., Maguire, M., Nield, P. C., Jenkins, R. E., Park, B. K., Krawczynska, K., . . . Boyd, M. T. (2011). MDM2 interacts with NME2 (non-metastatic cells 2, protein) and suppresses the ability of NME2 to negatively regulate cell motility. CARCINOGENESIS, 32(8), 1133-1142. doi:10.1093/carcin/bgr070Mass Spectrometric Characterization of Circulating and Functional Antigens Derived from Piperacillin in Patients with Cystic Fibrosis (Journal article)
Whitaker, P., Meng, X., Lavergne, S. N., El-Ghaiesh, S., Monshi, M., Earnshaw, C., . . . Park, B. K. (2011). Mass Spectrometric Characterization of Circulating and Functional Antigens Derived from Piperacillin in Patients with Cystic Fibrosis. JOURNAL OF IMMUNOLOGY, 187(1), 200-211. doi:10.4049/jimmunol.1100647Tetracycline-inducible protein expression in pancreatic cancer cells: Effects of CapG overexpression (Journal article)
Tonack, S., Patel, S., Jalali, M., Nedjadi, T., Jenkins, R. E., Goldring, C., . . . Costello, E. (2011). Tetracycline-inducible protein expression in pancreatic cancer cells: Effects of CapG overexpression. WORLD JOURNAL OF GASTROENTEROLOGY, 17(15), 1947-1960. doi:10.3748/wjg.v17.i15.1947Combined LC-MS/MS and iTRAQ analysis of serum and pancreatic juice for the detection of biomarkers for pancreatic cancer: Influence of biliary obstruction (Journal article)
Tonack, S., Jenkinson, C., Elliot, V., Dajani, K., Jenkins, R. E., Kitteringham, N. R., . . . Costello, E. (2011). Combined LC-MS/MS and iTRAQ analysis of serum and pancreatic juice for the detection of biomarkers for pancreatic cancer: Influence of biliary obstruction. Pancreas, 40, 1358.2010
Protein binding and pharmacokinetics of reactive acyl glucuronide drug metabolites (Journal article)
Hammond, T. G., Regan, S. L., Meng, X., Maggs, J. L., Jenkins, R. E., Kenna, G. L., . . . Park, B. K. (2010). Protein binding and pharmacokinetics of reactive acyl glucuronide drug metabolites. Toxicology, 278(3), 357-358. doi:10.1016/j.tox.2010.08.108Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer (Journal article)
Tweedle, E. M., Khattak, I., Ang, C. W., Nedjadi, T., Jenkins, R., Park, B. K., . . . Costello, E. (2010). Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer. GUT, 59(11), 1501-1510. doi:10.1136/gut.2009.196626Network Analysis of Primary Hepatocyte Dedifferentiation Using a Shotgun Proteomics Approach (Journal article)
Rowe, C., Goldring, C. E. P., Kitteringham, N. R., Jenkins, R. E., Lane, B. S., Sanderson, C., . . . Park, B. K. (2010). Network Analysis of Primary Hepatocyte Dedifferentiation Using a Shotgun Proteomics Approach. Journal of Proteome Research, 9(8), 4313-4314. doi:10.1021/pr100603eSmad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells (Journal article)
Ang, C. W., Nedjadi, T., Sheikh, A. A., Tweedle, E. M., Tonack, S., Honap, S., . . . Costello, E. (2010). Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells. CARCINOGENESIS, 31(9), 1541-1551. doi:10.1093/carcin/bgq137Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver (Journal article)
Kitteringham, N. R., Abdullah, A., Walsh, J., Randle, L., Jenkins, R. E., Sison, R., . . . Park, B. K. (2010). Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver. JOURNAL OF PROTEOMICS, 73(8), 1612-1631. doi:10.1016/j.jprot.2010.03.018Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway (Journal article)
Copple, I. M., Lister, A., Obeng, A. D., Kitteringham, N. R., Jenkins, R. E., Layfield, R., . . . Park, B. K. (2010). Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway. JOURNAL OF BIOLOGICAL CHEMISTRY, 285(22), 16782-16788. doi:10.1074/jbc.M109.096545Characterization of <i>p</i>-Phenylenediamine-Albumin Binding Sites and T-Cell Responses to Hapten-Modified Protein (Journal article)
Jenkinson, C., Jenkins, R. E., Aleksic, M., Pirmohamed, M., Naisbitt, D. J., & Park, B. K. (2010). Characterization of <i>p</i>-Phenylenediamine-Albumin Binding Sites and T-Cell Responses to Hapten-Modified Protein. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 130(3), 732-742. doi:10.1038/jid.2009.2712009
A technically detailed and pragmatic protocol for quantitative serum proteomics using iTRAQ (Journal article)
Tonack, S., Aspinall-O'Dea, M., Jenkins, R. E., Elliot, V., Murray, S., Lane, C. S., . . . Costello, E. (2009). A technically detailed and pragmatic protocol for quantitative serum proteomics using iTRAQ. JOURNAL OF PROTEOMICS, 73(2), 352-356. doi:10.1016/j.jprot.2009.07.009Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA <i>in vitro</i> and <i>in vivo</i> (Journal article)
Jenkins, R. E., Meng, X., Elliott, V. L., Kitteringham, N. R., Pirmohamed, M., & Park, B. K. (2009). Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA <i>in vitro</i> and <i>in vivo</i>. PROTEOMICS CLINICAL APPLICATIONS, 3(6), 720-729. doi:10.1002/prca.200800222S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility (Journal article)
Nedjadi, T., Kitteringham, N., Campbell, F., Jenkins, R. E., Park, B. K., Navarro, P., . . . Costello, E. (2009). S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility. BRITISH JOURNAL OF CANCER, 101(7), 1145-1154. doi:10.1038/sj.bjc.6605289Proteomic Analysis of Metastatic Laryngeal Squamous Cell Carcinoma (Journal article)
Goodyear, P., Jenkins, R., Kitteringham, N., Boyd, M., Hamlett, J., & Jones, T. (2009). Proteomic Analysis of Metastatic Laryngeal Squamous Cell Carcinoma. Clinical Oncology, 21(8), 645.A Mechanistic Investigation into the Irreversible Protein Binding and Antigenicity of <i>p</i>-Phenylenediamine (Journal article)
Jenkinson, C., Jenkins, R. E., Maggs, J. L., Kitteringham, N. R., Aleksic, M., Park, B. K., & Naisbitt, D. J. (2009). A Mechanistic Investigation into the Irreversible Protein Binding and Antigenicity of <i>p</i>-Phenylenediamine. CHEMICAL RESEARCH IN TOXICOLOGY, 22(6), 1172-1180. doi:10.1021/tx900095rMultiple Adduction Reactions of Nitroso Sulfamethoxazole with Cysteinyl Residues of Peptides and Proteins: Implications for Hapten Formation (Journal article)
Callan, H. E., Jenkins, R. E., Maggs, J. L., Lavergne, S. N., Clarke, S. E., Naisbitt, D. J., & Park, B. K. (2009). Multiple Adduction Reactions of Nitroso Sulfamethoxazole with Cysteinyl Residues of Peptides and Proteins: Implications for Hapten Formation. CHEMICAL RESEARCH IN TOXICOLOGY, 22(5), 937-948. doi:10.1021/tx900034rMultiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics. (Journal article)
Kitteringham, N. R., Jenkins, R. E., Lane, C. S., Elliott, V. L., & Park, B. K. (2009). Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(13), 1229-1239. doi:10.1016/j.jchromb.2008.11.013Confounding Effect of Obstructive Jaundice in the Interpretation of Proteomic Plasma Profiling Data for Pancreatic Cancer (Journal article)
Yan, L., Tonack, S., Smith, R., Dodd, S., Jenkins, R. E., Kitteringham, N., . . . Costello, E. (2009). Confounding Effect of Obstructive Jaundice in the Interpretation of Proteomic Plasma Profiling Data for Pancreatic Cancer. JOURNAL OF PROTEOME RESEARCH, 8(1), 142-148. doi:10.1021/pr800451hAn Investigation of the expression of cytochrome P450 3A7 and cytochrome P450 3A4 during stem cell differentiation for use as markers of emerging hepatic phenotype (Conference Paper)
Curley, P., Kelly, L., Shaw, R., Kitteringham, N., Jenkins, R., Alder, J., . . . Park, K. (2009). An Investigation of the expression of cytochrome P450 3A7 and cytochrome P450 3A4 during stem cell differentiation for use as markers of emerging hepatic phenotype. In British Pharmacology Society Winter Meeting. London, UK.2008
Phosphorylation of cysteine string protein on Serine 10 triggers 14-3-3 protein binding (Journal article)
Prescott, G. R., Jenkins, R. E., Walsh, C. M., & Morgan, A. (2008). Phosphorylation of cysteine string protein on Serine 10 triggers 14-3-3 protein binding. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 377(3), 809-814. doi:10.1016/j.bbrc.2008.10.069Proteomic analysis of metastatic laryngeal squamous cell carcinoma (Journal article)
Goodyear, P. W. A., Boyd, M. T., Jenkins, R., Hamlett, J., Kitteringham, N., & Jones, T. M. (2008). Proteomic analysis of metastatic laryngeal squamous cell carcinoma. Clinical Otolaryngology, 33(6), 642. doi:10.1111/j.1749-4486.2008.01843_5.xPROTEOMIC ANALYSIS OF SERUM AND PANCREATIC JUICE FROM PANCREATIC DUCTAL ADENOCARCINOMA PATIENS USING ITRAQ LABELLING (Journal article)
Tonack, S., Aspinall-O'Dea, M., Sheikh, A., Jenkins, R., Elliott, V., Neoptolemos, J., & Costello, E. (2008). PROTEOMIC ANALYSIS OF SERUM AND PANCREATIC JUICE FROM PANCREATIC DUCTAL ADENOCARCINOMA PATIENS USING ITRAQ LABELLING. Pancreas, 37(4), 498. doi:10.1097/01.mpa.0000335401.70046.ebThe hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system (Journal article)
Copple, I. M., Goldring, C. E., Jenkins, R. E., Chia, A. J. L., Randle, L. E., Hayes, J. D., . . . Park, B. K. (2008). The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. HEPATOLOGY, 48(4), 1292-1301. doi:10.1002/hep.22472MDM2 regulates dihydrofolate reductase activity through monoubiquitination (Journal article)
Maguire, M., Nield, P. C., Devling, T., Jenkins, R. E., Park, B. K., Polanski, R., . . . Boyd, M. T. (2008). MDM2 regulates dihydrofolate reductase activity through monoubiquitination. CANCER RESEARCH, 68(9), 3232-3242. doi:10.1158/0008-5472.CAN-07-5271Albumin and immunoglobulin depletion of human plasma (Journal article)
Jenkins, R. E., Kitteringham, N. R., Greenough, C., & Park, B. K. (2008). Albumin and immunoglobulin depletion of human plasma. Methods Mol Biol, 425, 15-25.Albumin and immunoglobulin depletion of human plasma. (Chapter)
Jenkins, R. E., Kitteringham, N. R., Greenough, C., & Park, B. K. (2008). Albumin and immunoglobulin depletion of human plasma.. In Unknown Book (Vol. 425, pp. 15-25). doi:10.1007/978-1-60327-210-0_2Glutathione-S-transferase pi as a model protein for the characterisation of chemically reactive metabolites. (Journal article)
Jenkins, R. E., Kitteringham, N. R., Goldring, C. E. P., Dowdall, S. M. J., Hamlett, J., Lane, C. S., . . . Park, B. K. (2008). Glutathione-S-transferase pi as a model protein for the characterisation of chemically reactive metabolites.. Proteomics, 8(2), 301-315. doi:10.1002/pmic.2007008432007
Cell shape-dependent Control of Ca2+ influx and cell cycle progression in Swiss 3T3 fibroblasts. (Journal article)
Pennington, S. R., Foster, B. J., Hawley, S. R., Jenkins, R. E., Zolle, O., White, M. R. H., . . . Simpson, A. W. M. (2007). Cell shape-dependent Control of Ca2+ influx and cell cycle progression in Swiss 3T3 fibroblasts.. The Journal of biological chemistry, 282(44), 32112-32120. doi:10.1074/jbc.m705067200INVOLVEMENT OF S100A6 (CALCYCLIN) IN PANCREATIC CANCER PROGRESSION (Journal article)
Nedjadi, T., Smith, R., Jenkins, R. E., & Costello, E. (2007). INVOLVEMENT OF S100A6 (CALCYCLIN) IN PANCREATIC CANCER PROGRESSION. Pancreas, 35(4), 419. doi:10.1097/01.mpa.0000297757.44337.a8Interaction between pancreatic cancer cells and tumour stromal monocytes (Journal article)
Sheikh, A. A., Vimalachandran, D., Jenkins, R., Campbell, F., Dodson, A. R., Neoptolemos, J. P., & Costello, E. (2007). Interaction between pancreatic cancer cells and tumour stromal monocytes. PANCREAS, 35(4), 427. doi:10.1097/01.mpa.0000297784.25519.d5Detection and biochemical characterisation of a novel polymorphism in the human <i>GSTP1</i> gene (Journal article)
Kitteringham, N. R., Palmer, L., Owen, A., Lian, L. -Y., Jenkins, R., Dowdall, S., . . . Goldring, C. E. (2007). Detection and biochemical characterisation of a novel polymorphism in the human <i>GSTP1</i> gene. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1770(8), 1240-1247. doi:10.1016/j.bbagen.2007.05.001Characterization of a bifunctional catalase-peroxidase of <i>Burkholderia cenocepacia</i> (Journal article)
Charalabous, P., Risk, J. M., Jenkins, R., Birss, A. J., Hart, C. A., & Smalley, J. W. (2007). Characterization of a bifunctional catalase-peroxidase of <i>Burkholderia cenocepacia</i>. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 50(1), 37-44. doi:10.1111/j.1574-695X.2007.00224.xThe expression of S100A8 in pancreatic cancer-associated monocytes is associated with the Smad4 status of pancreatic cancer cells (Journal article)
Sheikh, A. A., Vimalachandran, D., Thompson, C. C., Jenkins, R. E., Nedjadi, T., Shekouh, A., . . . Costello, E. (2007). The expression of S100A8 in pancreatic cancer-associated monocytes is associated with the Smad4 status of pancreatic cancer cells. PROTEOMICS, 7(11), 1929-1940. doi:10.1002/pmic.200700072Pancreatic cancer cells overexpress gelsolin family-capping proteins, which contribute to their cell motility (Journal article)
Thompson, C. C., Ashcroft, F. J., Patel, S., Saraga, G., Vimalachandran, D., Prime, W., . . . Costello, E. (2007). Pancreatic cancer cells overexpress gelsolin family-capping proteins, which contribute to their cell motility. GUT, 56(1), 95-106. doi:10.1136/gut.2005.0836912006
The expression of S100A8 in tumour-associated monocytes is directly associated with the Smad4 status of pancreatic cancer cells (Conference Paper)
Vimalachandran, D., Sheikh, A., Tweedle, E., Khattak, I., Thompson, C. C., Jenkins, R. E., . . . Costello, E. (2006). The expression of S100A8 in tumour-associated monocytes is directly associated with the Smad4 status of pancreatic cancer cells. In PANCREAS Vol. 33 (pp. 506). doi:10.1097/00006676-200611000-00233Use of proteomics in development of biomarkers and early markers of toxicity (Journal article)
Pennington, S., Kitteringham, N., Jenkins, R., Hunt, T., Webb, S., & Hunter, C. (2006). Use of proteomics in development of biomarkers and early markers of toxicity. Toxicology Letters, 164, S316. doi:10.1016/j.toxlet.2006.07.322Plasticity in cell defence: access to and reactivity of critical protein residues and DNA response elements (Journal article)
Goldring, C., Kitteringham, N., Jenkins, R., Copple, I., Jeannin, J. F., & Park, B. K. (2006). Plasticity in cell defence: access to and reactivity of critical protein residues and DNA response elements. JOURNAL OF EXPERIMENTAL BIOLOGY, 209(12), 2337-2343. doi:10.1242/jeb.02209Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags (Journal article)
Jenkins, R. E., Kitteringham, N. R., Hunter, C. L., Webb, S., Hunt, T. J., Elsby, R., . . . Park, B. K. (2006). Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags. PROTEOMICS, 6(6), 1934-1947. doi:10.1002/pmic.200500432Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes (Journal article)
Goldring, C. E. P., Kitteringham, N. R., Jenkins, R., Lovatt, C. A., Randle, L. E., Abdullah, A., . . . Park, B. K. (2006). Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 290(1), C104-C115. doi:10.1152/ajpcell.00133.2005Protein chip technology in proteomics analysis (Chapter)
Jenkins, R. E., & Pennington, S. R. (2006). Protein chip technology in proteomics analysis. In J. E. Van Eyk, & M. J. Dunn (Eds.), Proteomic and genomic analysis of cardiovascular disease (pp. 235-254). Weinheim: Wiley-VCH Verlag Gmbh & Co..2005
Proteomic analysis of liver protein expression in transgenic mice deficient in the transcription factor Nrf2 (Journal article)
Kitteringham, N., Abdullah, A., Jenkins, R., Goldring, C., Hayes, J. D., & Park, K. (2005). Proteomic analysis of liver protein expression in transgenic mice deficient in the transcription factor Nrf2. Drug Metabolism Reviews, 37, 23.Quantitative profiling of cytochromes P450 by isotope coded affinity tagging (Journal article)
Jenkins, R. E., Kitteringham, N. R., Hunt, T. J., Boucher, B. J., Minkoff, M. S., Elsby, R., . . . Park, B. K. (2005). Quantitative profiling of cytochromes P450 by isotope coded affinity tagging. Toxicology, 213(3), 260-261.Quantitative profiling of cytochromes P450 by isotope coded affinity tagging (Journal article)
Jenkins, R. E., Kitteringham, N. R., Hunt, T. J., Boucher, B. J., Minkoff, M. S., Elsby, R., . . . Park, B. K. (2005). Quantitative profiling of cytochromes P450 by isotope coded affinity tagging. Toxicology, 213(3), 260-261.Separation-independent approaches for protein expression profiling (Chapter)
Jenkins, R. E., & Pennington, S. R. (2005). Separation-independent approaches for protein expression profiling. In M. Dunn (Ed.), Encyclopaedia of Genetics, Genomics, Proteomics and Bioinformatics (pp. 1209-1220). Hoboken: John Wiley & Sons.2004
A method for the rapid depletion of albumin and immunoglobulin from human plasma (Journal article)
Greenough, C., Jenkins, R. E., Kitteringham, N. R., Pirmohamed, M., Park, B. K., & Pennington, S. R. (2004). A method for the rapid depletion of albumin and immunoglobulin from human plasma. PROTEOMICS, 4(10), 3107-3111. doi:10.1002/pmic.2003008152003
Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver. (Journal article)
Kitteringham, N. R., Powell, H., Jenkins, R. E., Hamlett, J., Lovatt, C., Elsby, R., . . . Park, B. K. (2003). Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver.. Proteomics, 3(2), 191-207. doi:10.1002/pmic.2003900282002
Identification of Ca<SUP>2+</SUP>-dependent binding partners for the neuronal calcium sensor protein neurocalcin δ:: interaction with actin, clathrin and tubulin (Journal article)
Ivings, L., Pennington, S. R., Jenkins, R., Weiss, J. L., & Burgoyne, R. D. (2002). Identification of Ca<SUP>2+</SUP>-dependent binding partners for the neuronal calcium sensor protein neurocalcin δ:: interaction with actin, clathrin and tubulin. BIOCHEMICAL JOURNAL, 363, 599-608. doi:10.1042/0264-6021:3630599Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin δ: interaction with actin, clathrin and tubulin (Journal article)
IVINGS, L., PENNINGTON, S. R., JENKINS, R., WEISS, J. L., & BURGOYNE, R. D. (2002). Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin δ: interaction with actin, clathrin and tubulin. Biochemical Journal, 363(3), 599-608. doi:10.1042/bj36305992001
Regulation of growth factor induced gene expression by calcium signalling: Integrated mRNA and protein expression analysis (Journal article)
Jenkins, R. E., Hawley, S. R., Promwikorn, W., Brown, J., Hamlett, J., & Pennington, S. R. (2001). Regulation of growth factor induced gene expression by calcium signalling: Integrated mRNA and protein expression analysis. Proteomics, 1(9), 1092-1104. doi:3.0.CO;2-S">10.1002/1615-9861(200109)1:9<1092::AID-PROT1092>3.0.CO;2-SDOI: 10.1002/1615-9861(200109)1:9<1092::AID-PROT1092>3.0.CO;2-S
Regulation of growth factor induced gene expression by calcium signalling: integrated mRNA and protein expression analysis. (Journal article)
Jenkins, R. E., Hawley, S. R., Promwikorn, W., Brown, J., Hamlett, J., & Pennington, S. R. (2001). Regulation of growth factor induced gene expression by calcium signalling: integrated mRNA and protein expression analysis.. Proteomics, 1(9), 1092-1104. doi:3.0.co;2-s">10.1002/1615-9861(200109)1:9<1092::aid-prot1092>3.0.co;2-sDOI: 10.1002/1615-9861(200109)1:9<1092::aid-prot1092>3.0.co;2-s