Computational models of pain neuroplasticity: From pathology to therapy
1:00pm - 2:00pm /
Wednesday 30th November 2016
/ Venue: Lesley Hearnshaw Lecture Theatre, Ground Floor Eleanor Rathbone Building
- 01517941106
- Dr Craig Thorley
- Suitable for: Staff and students
- Admission: Free
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Speaker: Dr Chris Brown, University of Liverpool
The phenomenon of neuroplasticity in the brain has profound implications for the diagnosis and treatment of patients suffering from chronic pain. Pain is strongly influenced by psychological context such as expectancy, mediated by activity in regions of the cerebral cortex which undergo neuroplastic changes in patients with chronic pain. I will discuss how such changes may contribute to chronic pain and how neurocomputational models of neuroplasticity based on predictive coding could lead to the development of new clinical tests and treatments. This will be illustrated with reference to past, ongoing and planned projects investigating biomarkers of neuroplasticity, brain mechanisms of mindfulness interventions and the development of electroceutical therapies.
The phenomenon of neuroplasticity in the brain has profound implications for the diagnosis and treatment of patients suffering from chronic pain. Pain is strongly influenced by psychological context such as expectancy, mediated by activity in regions of the cerebral cortex which undergo neuroplastic changes in patients with chronic pain. I will discuss how such changes may contribute to chronic pain and how neurocomputational models of neuroplasticity based on predictive coding could lead to the development of new clinical tests and treatments. This will be illustrated with reference to past, ongoing and planned projects investigating biomarkers of neuroplasticity, brain mechanisms of mindfulness interventions and the development of electroceutical therapies.