The Neurology working group aims to evaluate both the clinical phenotype of acute neurological complications and the medium-term neurological symptoms in 800 patients who have developed these complications at or around the time of SARS-CoV2 infection relative to 500 controls. We will then compare these clinical features to genetic, immunologic, virologic, biomarker, and neuroimaging findings to mechanistically stratify patients by underlying biological processes driving these complications.
We are employing standardised neurological assessments:
- We are working with the WHO and World Federation of Neurology to validate our Neurological Case Record Form through an international Inter-Observer Variability study
- We are working with the Global NeuroCOVID Coalition to translate the Core Neurological Assessment:
- English
- Italian - We have produced an accompanying Core Neurological Examination Training video
- We iteratively evaluate the spectrum of neurological (and psychiatric) manifestations of COVID-19 at the COVID-CNS Case Evaluation Panel fortnightly: members please email covidcns@kcl.ac.uk if you would like to be added to the calendar invite list.
Leads
- Professor Benedict Michael, University of Liverpool
- Professor Nicholas Wood, University College London.
Members
- Dr Laura Benjamin, University College London
- Dr David P Breen, University of Edinburgh
- Professor Gerome Breen, King’s College London
- Ceryce Collie, University of Liverpool
- Dr David Cousins, Newcastle University
- Dr Nicholas Davies, Imperial College London
- Dr Stella Hughes, Belfast Health and Social Care Trust
- Dr Tom Jenkins, Sheffield University
- Dr James Lilleker, University of Manchester
- Dr Gavin McDonnell, Belfast Health and Social Care Trust
- Sophie Pendered, University of Liverpool
- Professor Craig J Smith, University of Manchester
- Dr Arina Tamborska, University of Liverpool
- Dr Rhys Thomas, Newcastle University
- Professor Tom Solomon, University of Liverpool
- Dr Michael Zandi, University College London Hospitals.