For learners on the Clinical Anatomy with Education programme, the Principles of Human Anatomy module provides the foundational knowledge on which specialised and applied modules can be based. An introductory week is followed by a gradual progression through the key anatomical features of major body systems. Exploration of each system includes development, gross anatomy and function. Learning is through a mixture of asynchronous lectures, online seminars and independent study, across 11 online weeks. This is supported by guided access to a range of interactive digital anatomy resources. An intensive, on-campus week in the Human Anatomy Resource Centre (HARC) allows the opportunity to apply and contextualise knowledge through practical sessions, including cadaveric examination. Outcomes are assessed through a mixture of assessment types, including an extended written assignment and a spotter style exam.